Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	V	Q	R	I	T	I	A	P	Q	G	P	E	F	S	R	F	V	M	G	Y	W	R	L	M	D	W	N	M	S	A	R	Q	L	V	S	F	I	E	E	H	L	D	L	G	V	T	T	V	D	H	A	D	I	Y	G	G	Y	Q	C
Secondary structure
SS confidence
Disorder		?	?	?	?			?																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	A	A	F	G	E	A	L	K	L	A	P	H	L	R	E	R	M	E	I	V	S	K	C	G	I	A	T	T	A	R	E	E	N	V	I	G	H	Y	I	T	D	R	D	H	I	I	K	S	A	E	Q	S	L	I	N	L	A	T	D
Secondary structure
SS confidence
Disorder																															?	?	?	?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		H	L	D	L	L	L	I	H	R	P	D	P	L	M	D	A	D	E	V	A	D	A	F	K	H	L	H	Q	S	G	K	V	R	H	F	G	V	S	N	F	T	P	A	Q	F	A	L	L	Q	S	R	L	P	F	T	L	A	T	N	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	E	I	S	P	V	H	Q	P	L	L	L	D	G	T	L	D	Q	L	Q	Q	L	R	V	R	P	M	A	W	S	C	L	G	G	G	R	L	F	N	D	D	Y	F	Q	P	L	R	D	E	L	A	V	V	A	E	E	L	N	A	G
Secondary structure
SS confidence
Disorder																																						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
Sequence		S	I	E	Q	V	V	Y	A	W	V	L	R	L	P	S	Q	P	L	P	I	I	G	S	G	K	I	E	R	V	R	A	A	V	E	A	E	T	L	K	M	T	R	Q	Q	W	F	R	I	R	K	A	A	L	G	Y	D	V	P
Secondary structure
SS confidence
Disorder																																																						?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1ur3 chain M Region: 1 - 297 Aligned: 297 Modelled: 297 Confidence: 100.0% Identity: 97% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1lqa chain A Region: 2 - 298 Aligned: 293 Modelled: 297 Confidence: 100.0% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 3eau chain A domain 1 Region: 1 - 297 Aligned: 291 Modelled: 297 Confidence: 100.0% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 3lut chain A Region: 1 - 297 Aligned: 291 Modelled: 297 Confidence: 100.0% Identity: 22% PDB header:membrane protein Chain: A: PDB Molecule:voltage-gated potassium channel subunit beta-2; PDBTitle: a structural model for the full-length shaker potassium channel kv1.2 Phyre2 PDB 3erp chain A Region: 2 - 294 Aligned: 287 Modelled: 289 Confidence: 100.0% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of idp01002, a putative oxidoreductase from and essential2 gene of salmonella typhimurium Phyre2 PDB 3n6q chain F Region: 2 - 297 Aligned: 292 Modelled: 296 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: F: PDB Molecule:yghz aldo-keto reductase; PDBTitle: crystal structure of yghz from e. coli Phyre2 PDB 3n2t chain A Region: 1 - 298 Aligned: 290 Modelled: 298 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of the glycerol dehydrogenase akr11b4 from gluconobacter2 oxydans Phyre2 PDB 1pyf chain A Region: 3 - 293 Aligned: 281 Modelled: 291 Confidence: 100.0% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1pz1 chain A Region: 2 - 298 Aligned: 289 Modelled: 296 Confidence: 100.0% Identity: 26% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 3h7u chain A Region: 2 - 298 Aligned: 270 Modelled: 285 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:aldo-keto reductase; PDBTitle: crystal structure of the plant stress-response enzyme akr4c9 Phyre2 PDB 1ynp chain A Region: 2 - 298 Aligned: 269 Modelled: 279 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: aldo-keto reductase akr11c1 from bacillus halodurans (apo form) Phyre2 PDB 1gve chain A Region: 15 - 292 Aligned: 266 Modelled: 278 Confidence: 100.0% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1q5m chain A Region: 2 - 297 Aligned: 272 Modelled: 283 Confidence: 100.0% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 3up8 chain B Region: 6 - 293 Aligned: 256 Modelled: 281 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: B: PDB Molecule:putative 2,5-diketo-d-gluconic acid reductase b; PDBTitle: crystal structure of a putative 2,5-diketo-d-gluconic acid reductase b Phyre2 PDB 3f7j chain B Region: 1 - 298 Aligned: 264 Modelled: 298 Confidence: 100.0% Identity: 25% PDB header:oxidoreductase Chain: B: PDB Molecule:yvgn protein; PDBTitle: b.subtilis yvgn Phyre2 PDB 1mi3 chain A Region: 2 - 298 Aligned: 270 Modelled: 285 Confidence: 100.0% Identity: 25% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1j96 chain A Region: 2 - 297 Aligned: 273 Modelled: 296 Confidence: 100.0% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1us0 chain A Region: 2 - 298 Aligned: 273 Modelled: 285 Confidence: 100.0% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1qwk chain A Region: 3 - 297 Aligned: 268 Modelled: 283 Confidence: 100.0% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1afs chain A Region: 2 - 298 Aligned: 274 Modelled: 297 Confidence: 100.0% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 1 d1ur3m_ 2 d1lqaa_ 3 d3eaua1 4 c3lutA_ 5 c3erpA_ 6 c3n6qF_ 7 c3n2tA_ 8 d1pyfa_ 9 d1pz1a_ 10 c3h7uA_ 11 c1ynpA_ 12 d1gvea_ 13 d1q5ma_ 14 c3up8B_ 15 c3f7jB_ 16 d1mi3a_ 17 d1j96a_ 18 d1us0a_ 19 d1qwka_ 20 d1afsa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1ur3m_ 100.0 97 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 2 d1lqaa_ 100.0 23 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 3 d3eaua1 100.0 22 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 4 c3lutA_ 100.0 22 PDB header:membrane protein Chain: A: PDB Molecule:voltage-gated potassium channel subunit beta-2; PDBTitle: a structural model for the full-length shaker potassium channel kv1.2 5 c3erpA_ 100.0 25 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of idp01002, a putative oxidoreductase from and essential2 gene of salmonella typhimurium 6 c3n6qF_ 100.0 22 PDB header:oxidoreductase Chain: F: PDB Molecule:yghz aldo-keto reductase; PDBTitle: crystal structure of yghz from e. coli 7 c3n2tA_ 100.0 26 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of the glycerol dehydrogenase akr11b4 from gluconobacter2 oxydans 8 d1pyfa_ 100.0 23 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 9 d1pz1a_ 100.0 26 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 10 c3h7uA_ 100.0 26 PDB header:oxidoreductase Chain: A: PDB Molecule:aldo-keto reductase; PDBTitle: crystal structure of the plant stress-response enzyme akr4c9 11 c1ynpA_ 100.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: aldo-keto reductase akr11c1 from bacillus halodurans (apo form) 12 d1gvea_ 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 13 d1q5ma_ 100.0 21 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 14 c3up8B_ 100.0 27 PDB header:oxidoreductase Chain: B: PDB Molecule:putative 2,5-diketo-d-gluconic acid reductase b; PDBTitle: crystal structure of a putative 2,5-diketo-d-gluconic acid reductase b 15 c3f7jB_ 100.0 25 PDB header:oxidoreductase Chain: B: PDB Molecule:yvgn protein; PDBTitle: b.subtilis yvgn 16 d1mi3a_ 100.0 25 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 17 d1j96a_ 100.0 21 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 18 d1us0a_ 100.0 22 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 19 d1qwka_ 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 20 d1afsa_ 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 21 d1frba_ not modelled 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 22 d1hqta_ not modelled 100.0 23 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 23 c2bp1C_ not modelled 100.0 22 PDB header:oxidoreductase Chain: C: PDB Molecule:aflatoxin b1 aldehyde reductase member 2; PDBTitle: structure of the aflatoxin aldehyde reductase in complex2 with nadph 24 c1zgdB_ not modelled 100.0 24 PDB header:plant protein Chain: B: PDB Molecule:chalcone reductase; PDBTitle: chalcone reductase complexed with nadp+ at 1.7 angstrom2 resolution 25 c2wztA_ not modelled 100.0 24 PDB header:oxidoreductase Chain: A: PDB Molecule:aldo-keto reductase; PDBTitle: crystal structure of a mycobacterium aldo-keto reductase in2 its apo and liganded form 26 d1mzra_ not modelled 100.0 24 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 27 c3h7rA_ not modelled 100.0 27 PDB header:oxidoreductase Chain: A: PDB Molecule:aldo-keto reductase; PDBTitle: crystal structure of the plant stress-response enzyme akr4c8 28 d1hw6a_ not modelled 100.0 24 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 29 c3o0kB_ not modelled 100.0 27 PDB header:oxidoreductase Chain: B: PDB Molecule:aldo/keto reductase; PDBTitle: crystal structure of aldo/keto reductase from brucella melitensis 30 c3buvB_ not modelled 100.0 20 PDB header:oxidoreductase Chain: B: PDB Molecule:3-oxo-5-beta-steroid 4-dehydrogenase; PDBTitle: crystal structure of human delta(4)-3-ketosteroid 5-beta-reductase in2 complex with nadp and hepes. resolution: 1.35 a. 31 c1vbjB_ not modelled 100.0 23 PDB header:oxidoreductase Chain: B: PDB Molecule:prostaglandin f synthase; PDBTitle: the crystal structure of prostaglandin f synthase from2 trypanosoma brucei 32 d1s1pa_ not modelled 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 33 d1ah4a_ not modelled 100.0 22 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 34 d2alra_ not modelled 100.0 24 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 35 c3b3dA_ not modelled 100.0 27 PDB header:oxidoreductase Chain: A: PDB Molecule:putative morphine dehydrogenase; PDBTitle: b.subtilis ytbe 36 d1vp5a_ not modelled 100.0 24 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 37 d1c9wa_ not modelled 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 38 c2bgsA_ not modelled 100.0 25 PDB header:oxidoreductase Chain: A: PDB Molecule:aldose reductase; PDBTitle: holo aldose reductase from barley 39 c3krbB_ not modelled 100.0 25 PDB header:oxidoreductase Chain: B: PDB Molecule:aldose reductase; PDBTitle: structure of aldose reductase from giardia lamblia at 1.75a resolution 40 c3ln3A_ not modelled 100.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrodiol dehydrogenase; PDBTitle: crystal structure of putative reductase (np_038806.2) from2 mus musculus at 1.18 a resolution 41 c3ktcB_ not modelled 82.1 12 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_050048.1) from2 erwinia carotovora atroseptica scri1043 at 1.54 a resolution 42 c3l23A_ not modelled 58.0 11 PDB header:isomerase Chain: A: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of sugar phosphate isomerase/epimerase2 (yp_001303399.1) from parabacteroides distasonis atcc 8503 at 1.70 a3 resolution 43 d1jpma1 not modelled 50.6 15 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 44 d3bofa2 not modelled 49.9 9 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 45 c3ezxA_ not modelled 41.7 14 PDB header:transferase Chain: A: PDB Molecule:monomethylamine corrinoid protein 1; PDBTitle: structure of methanosarcina barkeri monomethylamine2 corrinoid protein 46 c2ph5A_ not modelled 40.3 16 PDB header:transferase Chain: A: PDB Molecule:homospermidine synthase; PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54 47 d2gjxa1 not modelled 30.8 17 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 48 c3g8rA_ not modelled 30.1 19 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 49 c1jpmB_ not modelled 29.7 14 PDB header:isomerase Chain: B: PDB Molecule:l-ala-d/l-glu epimerase; PDBTitle: l-ala-d/l-glu epimerase 50 c3a5vA_ not modelled 25.7 18 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: crystal structure of alpha-galactosidase i from mortierella vinacea 51 c2pz0B_ not modelled 24.1 8 PDB header:hydrolase Chain: B: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of glycerophosphodiester phosphodiesterase (gdpd)2 from t. tengcongensis 52 c3lmyA_ not modelled 23.1 17 PDB header:hydrolase Chain: A: PDB Molecule:beta-hexosaminidase subunit beta; PDBTitle: the crystal structure of beta-hexosaminidase b in complex with2 pyrimethamine 53 c1b8hA_ not modelled 22.7 4 PDB header:transferase Chain: A: PDB Molecule:dna polymerase processivity component; PDBTitle: sliding clamp, dna polymerase 54 c2k6xA_ not modelled 22.4 15 PDB header:transcription Chain: A: PDB Molecule:rna polymerase sigma factor rpod; PDBTitle: autoregulation of a group 1 bacterial sigma factor involves2 the formation of a region 1.1- induced compacted structure 55 c3obeB_ not modelled 21.4 10 PDB header:isomerase Chain: B: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of a sugar phosphate isomerase/epimerase (bdi_3400)2 from parabacteroides distasonis atcc 8503 at 1.70 a resolution 56 c2zvrA_ not modelled 21.3 9 PDB header:isomerase Chain: A: PDB Molecule:uncharacterized protein tm_0416; PDBTitle: crystal structure of a d-tagatose 3-epimerase-related2 protein from thermotoga maritima 57 d1qbaa3 not modelled 21.1 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 58 c2gjxE_ not modelled 20.9 13 PDB header:hydrolase Chain: E: PDB Molecule:beta-hexosaminidase alpha chain; PDBTitle: crystallographic structure of human beta-hexosaminidase a 59 c2jlhA_ not modelled 20.2 15 PDB header:protein transport Chain: A: PDB Molecule:yop proteins translocation protein u; PDBTitle: crystal structure of the cytoplasmic domain of yersinia2 pestis yscu n263a mutant 60 c1nouA_ not modelled 20.1 17 PDB header:hydrolase Chain: A: PDB Molecule:beta-hexosaminidase beta chain; PDBTitle: native human lysosomal beta-hexosaminidase isoform b 61 d1nowa1 not modelled 19.8 17 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 62 c3dx5A_ not modelled 19.6 9 PDB header:lyase Chain: A: PDB Molecule:uncharacterized protein asbf; PDBTitle: crystal structure of the probable 3-dhs dehydratase asbf involved in2 the petrobactin synthesis from bacillus anthracis 63 c1uasA_ not modelled 19.0 11 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: crystal structure of rice alpha-galactosidase 64 d1yx1a1 not modelled 17.7 13 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:KguE-like 65 d2d0oa1 not modelled 17.3 12 Fold:The "swivelling" beta/beta/alpha domain Superfamily:Swiveling domain of dehydratase reactivase alpha subunit Family:Swiveling domain of dehydratase reactivase alpha subunit 66 d2nu7a1 not modelled 17.0 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 67 c2ylaA_ not modelled 16.9 8 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: inhibition of the pneumococcal virulence factor strh and2 molecular insights into n-glycan recognition and3 hydrolysis 68 c1wlzD_ not modelled 16.8 22 PDB header:unknown function Chain: D: PDB Molecule:cap-binding protein complex interacting protein PDBTitle: crystal structure of djbp fragment which was obtained by2 limited proteolysis 69 d1wlza1 not modelled 16.8 22 Fold:EF Hand-like Superfamily:EF-hand Family:EF-hand modules in multidomain proteins 70 d1k77a_ not modelled 16.1 11 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Hypothetical protein YgbM (EC1530) 71 c3qy6A_ not modelled 15.6 10 PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase ywqe; PDBTitle: crystal structures of ywqe from bacillus subtilis and cpsb from2 streptococcus pneumoniae, unique metal-dependent tyrosine3 phosphatases 72 c2wjeA_ not modelled 15.3 21 PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase cpsb; PDBTitle: crystal structure of the tyrosine phosphatase cps4b from2 steptococcus pneumoniae tigr4. 73 c3t7yB_ not modelled 15.2 12 PDB header:protein transport Chain: B: PDB Molecule:yop proteins translocation protein u; PDBTitle: structure of an autocleavage-inactive mutant of the cytoplasmic domain2 of ct091, the yscu homologue of chlamydia trachomatis 74 c3rcnA_ not modelled 15.0 13 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: crystal structure of beta-n-acetylhexosaminidase from arthrobacter2 aurescens 75 c1vliA_ not modelled 14.8 12 PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution 76 c3c00B_ not modelled 14.5 8 PDB header:membrane protein, protein transport Chain: B: PDB Molecule:escu; PDBTitle: crystal structural of the mutated g247t escu/spas c-terminal domain 77 c3nsnA_ not modelled 14.4 14 PDB header:hydrolase Chain: A: PDB Molecule:n-acetylglucosaminidase; PDBTitle: crystal structure of insect beta-n-acetyl-d-hexosaminidase ofhex12 complexed with tmg-chitotriomycin 78 c2yl8A_ not modelled 14.4 16 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: inhibition of the pneumococcal virulence factor strh and2 molecular insights into n-glycan recognition and3 hydrolysis 79 c1t0oA_ not modelled 14.3 13 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: the structure of alpha-galactosidase from trichoderma reesei complexed2 with beta-d-galactose 80 c3ic5A_ not modelled 14.3 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative saccharopine dehydrogenase; PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi. 81 c3bzrA_ not modelled 13.9 8 PDB header:membrane protein, protein transport Chain: A: PDB Molecule:escu; PDBTitle: crystal structure of escu c-terminal domain with n262d mutation, space2 group p 41 21 2 82 d3bzra1 not modelled 13.9 8 Fold:EscU C-terminal domain-like Superfamily:EscU C-terminal domain-like Family:EscU C-terminal domain-like 83 c3js3C_ not modelled 13.6 17 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of type i 3-dehydroquinate dehydratase (arod) from2 clostridium difficile with covalent reaction intermediate 84 d1yhta1 not modelled 13.1 24 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 85 d1jw2a_ not modelled 12.9 13 Fold:Open three-helical up-and-down bundle Superfamily:Hemolysin expression modulating protein HHA Family:Hemolysin expression modulating protein HHA 86 d1qwga_ not modelled 12.8 17 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 87 d1lk3a_ not modelled 12.8 16 Fold:4-helical cytokines Superfamily:4-helical cytokines Family:Interferons/interleukin-10 (IL-10) 88 d1szna2 not modelled 12.7 17 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 89 c2p10D_ not modelled 12.7 12 PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution 90 d1bxni_ not modelled 12.6 19 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 91 c2vwtA_ not modelled 12.4 21 PDB header:lyase Chain: A: PDB Molecule:yfau, 2-keto-3-deoxy sugar aldolase; PDBTitle: crystal structure of yfau, a metal ion dependent class ii2 aldolase from escherichia coli k12 - mg-pyruvate product3 complex 92 d1bwvs_ not modelled 12.0 13 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 93 c3rpmA_ not modelled 11.9 16 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetyl-hexosaminidase; PDBTitle: crystal structure of the first gh20 domain of a novel beta-n-acetyl-2 hexosaminidase strh from streptococcus pneumoniae r6 94 d1vlia2 not modelled 11.7 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 95 c3pjwA_ not modelled 11.6 13 PDB header:lyase Chain: A: PDB Molecule:cyclic dimeric gmp binding protein; PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23 96 d2p10a1 not modelled 11.4 12 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Mll9387-like 97 c1m04A_ not modelled 11.1 4 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: mutant streptomyces plicatus beta-hexosaminidase (d313n) in complex2 with product (glcnac) 98 c2ksnA_ not modelled 11.0 21 PDB header:signaling protein Chain: A: PDB Molecule:ubiquitin domain-containing protein 2; PDBTitle: solution structure of the n-terminal domain of dc-ubp/ubtd2 99 c1ydnA_ not modelled 11.0 20 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35.

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0