Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	K	T	L	Y	E	K	L	F	D	A	H	V	V	Y	E	A	E	N	E	T	P	L	L	Y	I	D	R	H	L	V	H	E	V	T	S	P	Q	A	F	D	G	L	R	A	H	G	R	P	V	R	Q	P	G	K	T	F	A	T
Secondary structure
SS confidence
Disorder		?	?	?	?										?		?	?	?																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	D	H	N	V	S	T	Q	T	K	D	I	N	A	C	G	E	M	A	R	I	Q	M	Q	E	L	I	K	N	C	K	E	F	G	V	E	L	Y	D	L	N	H	P	Y	Q	G	I	V	H	V	M	G	P	E	Q	G	V	T	L	P
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	M	T	I	V	C	G	D	S	H	T	A	T	H	G	A	F	G	A	L	A	F	G	I	G	T	S	E	V	E	H	V	L	A	T	Q	T	L	K	Q	G	R	A	K	T	M	K	I	E	V	Q	G	K	A	A	P	G	I	T	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	D	I	V	L	A	I	I	G	K	T	G	S	A	G	G	T	G	H	V	V	E	F	C	G	E	A	I	R	D	L	S	M	E	G	R	M	T	L	C	N	M	A	I	E	M	G	A	K	A	G	L	V	A	P	D	E	T	T	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		N	Y	V	K	G	R	L	H	A	P	K	G	K	D	F	D	D	A	V	A	Y	W	K	T	L	Q	T	D	E	G	A	T	F	D	T	V	V	T	L	Q	A	E	E	I	S	P	Q	V	T	W	G	T	N	P	G	Q	V	I	S	V
Secondary structure
SS confidence
Disorder											?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		N	D	N	I	P	D	P	A	S	F	A	D	P	V	E	R	A	S	A	E	K	A	L	A	Y	M	G	L	K	P	G	I	P	L	T	E	V	A	I	D	K	V	F	I	G	S	C	T	N	S	R	I	E	D	L	R	A	A	A	E
Secondary structure
SS confidence
Disorder					?						?		?	?	?	?	?	?	?										?	?		?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		I	A	K	G	R	K	V	A	P	G	V	Q	A	L	V	V	P	G	S	G	P	V	K	A	Q	A	E	A	E	G	L	D	K	I	F	I	E	A	G	F	E	W	R	L	P	G	C	S	M	C	L	A	M	N	N	D	R	L	N	P
Secondary structure
SS confidence
Disorder				?																																																	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.
Sequence		G	E	R	C	A	S	T	S	N	R	N	F	E	G	R	Q	G	R	G	G	R	T	H	L	V	S	P	A	M	A	A	A	A	A	V	T	G	H	F	A	D	I	R	N	I	K
Secondary structure
SS confidence
Disorder																																									?	?		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1aco chain A domain 2 Region: 2 - 464 Aligned: 431 Modelled: 439 Confidence: 100.0% Identity: 25% Fold: Aconitase iron-sulfur domain Superfamily: Aconitase iron-sulfur domain Family: Aconitase iron-sulfur domain Phyre2 PDB 1l5j chain A domain 3 Region: 1 - 466 Aligned: 418 Modelled: 429 Confidence: 100.0% Identity: 25% Fold: Aconitase iron-sulfur domain Superfamily: Aconitase iron-sulfur domain Family: Aconitase iron-sulfur domain Phyre2 PDB 2b3y chain A domain 2 Region: 6 - 464 Aligned: 455 Modelled: 459 Confidence: 100.0% Identity: 25% Fold: Aconitase iron-sulfur domain Superfamily: Aconitase iron-sulfur domain Family: Aconitase iron-sulfur domain Phyre2 PDB 2b3y chain B Region: 6 - 466 Aligned: 457 Modelled: 461 Confidence: 100.0% Identity: 25% PDB header:lyase Chain: B: PDB Molecule:iron-responsive element binding protein 1; PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1) Phyre2 PDB 5acn chain A Region: 2 - 466 Aligned: 433 Modelled: 442 Confidence: 100.0% Identity: 25% PDB header:lyase(carbon-oxygen) Chain: A: PDB Molecule:aconitase; PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal Phyre2 PDB 1l5j chain B Region: 1 - 466 Aligned: 416 Modelled: 431 Confidence: 100.0% Identity: 25% PDB header:lyase Chain: B: PDB Molecule:aconitate hydratase 2; PDBTitle: crystal structure of e. coli aconitase b. Phyre2 PDB 3bol chain B Region: 343 - 403 Aligned: 61 Modelled: 61 Confidence: 69.9% Identity: 23% PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ Phyre2 PDB 3bof chain A domain 2 Region: 343 - 369 Aligned: 27 Modelled: 27 Confidence: 61.6% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Homocysteine S-methyltransferase Family: Homocysteine S-methyltransferase Phyre2 PDB 3iz5 chain Q Region: 82 - 156 Aligned: 66 Modelled: 75 Confidence: 40.4% Identity: 12% PDB header:ribosome Chain: Q: PDB Molecule:60s ribosomal protein l5 (l18p); PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome Phyre2 PDB 1lt7 chain A Region: 343 - 366 Aligned: 24 Modelled: 24 Confidence: 31.1% Identity: 29% Fold: TIM beta/alpha-barrel Superfamily: Homocysteine S-methyltransferase Family: Homocysteine S-methyltransferase Phyre2 PDB 1umy chain A Region: 343 - 369 Aligned: 27 Modelled: 27 Confidence: 28.3% Identity: 26% Fold: TIM beta/alpha-barrel Superfamily: Homocysteine S-methyltransferase Family: Homocysteine S-methyltransferase Phyre2 PDB 1ni5 chain A Region: 37 - 98 Aligned: 52 Modelled: 62 Confidence: 26.9% Identity: 17% PDB header:cell cycle Chain: A: PDB Molecule:putative cell cycle protein mesj; PDBTitle: structure of the mesj pp-atpase from escherichia coli Phyre2 PDB 2o2q chain A Region: 202 - 249 Aligned: 47 Modelled: 48 Confidence: 21.8% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp Phyre2 PDB 2e21 chain A Region: 37 - 98 Aligned: 52 Modelled: 62 Confidence: 20.4% Identity: 15% PDB header:ligase Chain: A: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus. Phyre2 PDB 3io1 chain B Region: 345 - 456 Aligned: 109 Modelled: 112 Confidence: 19.9% Identity: 13% PDB header:hydrolase Chain: B: PDB Molecule:aminobenzoyl-glutamate utilization protein; PDBTitle: crystal structure of aminobenzoyl-glutamate utilization2 protein from klebsiella pneumoniae Phyre2 PDB 1pt1 chain B Region: 343 - 380 Aligned: 36 Modelled: 38 Confidence: 19.9% Identity: 19% PDB header:lyase Chain: B: PDB Molecule:aspartate 1-decarboxylase; PDBTitle: unprocessed pyruvoyl dependent aspartate decarboxylase with histidine2 11 mutated to alanine Phyre2 PDB 1ml4 chain A domain 2 Region: 333 - 390 Aligned: 50 Modelled: 58 Confidence: 19.4% Identity: 16% Fold: ATC-like Superfamily: Aspartate/ornithine carbamoyltransferase Family: Aspartate/ornithine carbamoyltransferase Phyre2 PDB 1ppy chain A Region: 343 - 380 Aligned: 36 Modelled: 38 Confidence: 19.4% Identity: 19% Fold: Double psi beta-barrel Superfamily: ADC-like Family: Pyruvoyl dependent aspartate decarboxylase, ADC Phyre2 PDB 1o60 chain A Region: 195 - 360 Aligned: 111 Modelled: 109 Confidence: 19.3% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 2oxl chain A Region: 175 - 191 Aligned: 17 Modelled: 17 Confidence: 18.6% Identity: 24% PDB header:gene regulation Chain: A: PDB Molecule:hypothetical protein ymgb; PDBTitle: structure and function of the e. coli protein ymgb: a protein critical2 for biofilm formation and acid resistance Phyre2 1 d1acoa2 2 d1l5ja3 3 d2b3ya2 4 c2b3yB_ 5 c5acnA_ 6 c1l5jB_ 7 c3bolB_ 8 d3bofa2 9 c3iz5Q_ 10 d1lt7a_ 11 d1umya_ 12 c1ni5A_ 13 c2o2qA_ 14 c2e21A_ 15 c3io1B_ 16 c1pt1B_ 17 d1ml4a2 18 d1ppya_ 19 d1o60a_ 20 c2oxlA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1acoa2 100.0 25 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 2 d1l5ja3 100.0 25 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 3 d2b3ya2 100.0 25 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 4 c2b3yB_ 100.0 25 PDB header:lyase Chain: B: PDB Molecule:iron-responsive element binding protein 1; PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1) 5 c5acnA_ 100.0 25 PDB header:lyase(carbon-oxygen) Chain: A: PDB Molecule:aconitase; PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal 6 c1l5jB_ 100.0 25 PDB header:lyase Chain: B: PDB Molecule:aconitate hydratase 2; PDBTitle: crystal structure of e. coli aconitase b. 7 c3bolB_ 69.9 23 PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ 8 d3bofa2 61.6 19 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 9 c3iz5Q_ 40.4 12 PDB header:ribosome Chain: Q: PDB Molecule:60s ribosomal protein l5 (l18p); PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 10 d1lt7a_ 31.1 29 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 11 d1umya_ 28.3 26 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 12 c1ni5A_ 26.9 17 PDB header:cell cycle Chain: A: PDB Molecule:putative cell cycle protein mesj; PDBTitle: structure of the mesj pp-atpase from escherichia coli 13 c2o2qA_ 21.8 26 PDB header:oxidoreductase Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp 14 c2e21A_ 20.4 15 PDB header:ligase Chain: A: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus. 15 c3io1B_ 19.9 13 PDB header:hydrolase Chain: B: PDB Molecule:aminobenzoyl-glutamate utilization protein; PDBTitle: crystal structure of aminobenzoyl-glutamate utilization2 protein from klebsiella pneumoniae 16 c1pt1B_ 19.9 19 PDB header:lyase Chain: B: PDB Molecule:aspartate 1-decarboxylase; PDBTitle: unprocessed pyruvoyl dependent aspartate decarboxylase with histidine2 11 mutated to alanine 17 d1ml4a2 19.4 16 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 18 d1ppya_ 19.4 19 Fold:Double psi beta-barrel Superfamily:ADC-like Family:Pyruvoyl dependent aspartate decarboxylase, ADC 19 d1o60a_ 19.3 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 20 c2oxlA_ 18.6 24 PDB header:gene regulation Chain: A: PDB Molecule:hypothetical protein ymgb; PDBTitle: structure and function of the e. coli protein ymgb: a protein critical2 for biofilm formation and acid resistance 21 c3fseB_ not modelled 17.7 10 PDB header:hydrolase Chain: B: PDB Molecule:two-domain protein containing dj-1/thij/pfpi-like and PDBTitle: crystal structure of a two-domain protein containing dj-1/thij/pfpi-2 like and ferritin-like domains (ava_4496) from anabaena variabilis3 atcc 29413 at 1.90 a resolution 22 c2zkrn_ not modelled 17.6 18 PDB header:ribosomal protein/rna Chain: N: PDB Molecule:rna expansion segment es27; PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map 23 c2xivA_ not modelled 17.6 15 PDB header:structural protein Chain: A: PDB Molecule:hypothetical invasion protein; PDBTitle: structure of rv1477, hypothetical invasion protein of2 mycobacterium tuberculosis 24 c2c45F_ not modelled 15.8 28 PDB header:lyase Chain: F: PDB Molecule:aspartate 1-decarboxylase precursor; PDBTitle: native precursor of pyruvoyl dependent aspartate2 decarboxylase 25 c2gp4A_ not modelled 15.6 19 PDB header:lyase Chain: A: PDB Molecule:6-phosphogluconate dehydratase; PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis 26 d1ejba_ not modelled 14.9 21 Fold:Lumazine synthase Superfamily:Lumazine synthase Family:Lumazine synthase 27 c2duwA_ not modelled 14.0 26 PDB header:ligand binding protein Chain: A: PDB Molecule:putative coa-binding protein; PDBTitle: solution structure of putative coa-binding protein of2 klebsiella pneumoniae 28 c2w9mB_ not modelled 13.6 20 PDB header:dna replication Chain: B: PDB Molecule:polymerase x; PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans 29 c4a1aM_ not modelled 13.5 20 PDB header:ribosome Chain: M: PDB Molecule:60s ribosomal protein l5; PDBTitle: t.thermophila 60s ribosomal subunit in complex with2 initiation factor 6. this file contains 5s rrna,3 5.8s rrna and proteins of molecule 3. 30 c1htrP_ not modelled 13.3 19 PDB header:aspartyl protease Chain: P: PDB Molecule:progastricsin (pro segment); PDBTitle: crystal and molecular structures of human progastricsin at 1.622 angstroms resolution 31 c3izcQ_ not modelled 13.0 18 PDB header:ribosome Chain: Q: PDB Molecule:60s ribosomal protein rpl5 (l18p); PDBTitle: localization of the large subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome 32 d1oi4a1 not modelled 12.0 30 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:DJ-1/PfpI 33 c2jz2A_ not modelled 11.5 28 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ssl0352 protein; PDBTitle: solution nmr structure of ssl0352 protein from synechocystis sp. pcc2 6803. northeast structural genomics consortium target sgr42 34 d1rvv1_ not modelled 11.4 15 Fold:Lumazine synthase Superfamily:Lumazine synthase Family:Lumazine synthase 35 c3uk7B_ not modelled 11.3 26 PDB header:transferase Chain: B: PDB Molecule:class i glutamine amidotransferase-like domain-containing PDBTitle: crystal structure of arabidopsis thaliana dj-1d 36 d1c0aa2 not modelled 10.9 27 Fold:DCoH-like Superfamily:GAD domain-like Family:GAD domain 37 c2ebbA_ not modelled 10.6 18 PDB header:lyase Chain: A: PDB Molecule:pterin-4-alpha-carbinolamine dehydratase; PDBTitle: crystal structure of pterin-4-alpha-carbinolamine2 dehydratase (pterin carbinolamine dehydratase) from3 geobacillus kaustophilus hta426 38 c3hazA_ not modelled 10.5 13 PDB header:oxidoreductase Chain: A: PDB Molecule:proline dehydrogenase; PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein 39 c2jzfA_ not modelled 10.3 39 PDB header:viral protein Chain: A: PDB Molecule:replicase polyprotein 1ab; PDBTitle: nmr conformer closest to the mean coordinates of the domain 513-651 of2 the sars-cov nonstructural protein nsp3 40 d2ga5a1 not modelled 9.7 29 Fold:N domain of copper amine oxidase-like Superfamily:Frataxin/Nqo15-like Family:Frataxin-like 41 c3zquA_ not modelled 9.6 19 PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: structure of a probable aromatic acid decarboxylase 42 d1obra_ not modelled 9.5 33 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Carboxypeptidase T 43 c2fgxA_ not modelled 9.5 30 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative thioredoxin; PDBTitle: solution nmr structure of protein ne2328 from nitrosomonas2 europaea. northeast structural genomics consortium target3 net3. 44 c2x24B_ not modelled 9.5 8 PDB header:ligase Chain: B: PDB Molecule:acetyl-coa carboxylase; PDBTitle: bovine acc2 ct domain in complex with inhibitor 45 c1xovA_ not modelled 9.5 8 PDB header:hydrolase Chain: A: PDB Molecule:ply protein; PDBTitle: the crystal structure of the listeria monocytogenes bacteriophage psa2 endolysin plypsa 46 d1skye2 not modelled 9.3 8 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:N-terminal domain of alpha and beta subunits of F1 ATP synthase Family:N-terminal domain of alpha and beta subunits of F1 ATP synthase 47 d1d3va_ not modelled 8.9 28 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 48 c3m1rF_ not modelled 8.9 28 PDB header:hydrolase Chain: F: PDB Molecule:formimidoylglutamase; PDBTitle: the crystal structure of formimidoylglutamase from bacillus2 subtilis subsp. subtilis str. 168 49 d1woha_ not modelled 8.8 28 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 50 c3h8aF_ not modelled 8.7 17 PDB header:lyase/protein binding Chain: F: PDB Molecule:rnase e; PDBTitle: crystal structure of e. coli enolase bound to its cognate rnase e2 recognition domain 51 c2yb1A_ not modelled 8.6 20 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase; PDBTitle: structure of an amidohydrolase from chromobacterium violaceum (efi2 target efi-500202) with bound mn, amp and phosphate. 52 d1v8ba2 not modelled 8.6 21 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:S-adenosylhomocystein hydrolase 53 d1sqda2 not modelled 8.5 25 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family:Extradiol dioxygenases 54 d2gp4a2 not modelled 8.5 19 Fold:IlvD/EDD N-terminal domain-like Superfamily:IlvD/EDD N-terminal domain-like Family:lvD/EDD N-terminal domain-like 55 c3h8aE_ not modelled 8.2 18 PDB header:lyase/protein binding Chain: E: PDB Molecule:rnase e; PDBTitle: crystal structure of e. coli enolase bound to its cognate rnase e2 recognition domain 56 c3qpbB_ not modelled 8.2 18 PDB header:transferase Chain: B: PDB Molecule:uridine phosphorylase; PDBTitle: crystal structure of streptococcus pyogenes uridine phosphorylase2 reveals a subclass of the np-i superfamily 57 d1c41a_ not modelled 8.0 17 Fold:Lumazine synthase Superfamily:Lumazine synthase Family:Lumazine synthase 58 d1tska_ not modelled 8.0 71 Fold:Knottins (small inhibitors, toxins, lectins) Superfamily:Scorpion toxin-like Family:Short-chain scorpion toxins 59 c2ejbA_ not modelled 7.9 14 PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: crystal structure of phenylacrylic acid decarboxylase from2 aquifex aeolicus 60 d1ru0a_ not modelled 7.8 15 Fold:DCoH-like Superfamily:PCD-like Family:PCD-like 61 c2k89A_ not modelled 7.8 29 PDB header:protein binding Chain: A: PDB Molecule:phospholipase a-2-activating protein; PDBTitle: solution structure of a novel ubiquitin-binding domain from2 human plaa (pfuc, gly76-pro77 cis isomer) 62 d2z06a1 not modelled 7.7 15 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TTHA0625-like 63 d1iuka_ not modelled 7.6 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 64 c3pbiA_ not modelled 7.5 14 PDB header:hydrolase Chain: A: PDB Molecule:invasion protein; PDBTitle: structure of the peptidoglycan hydrolase ripb (rv1478) from2 mycobacterium tuberculosis at 1.6 resolution 65 c2wwaJ_ not modelled 7.5 21 PDB header:ribosome Chain: J: PDB Molecule:60s ribosomal protein l19; PDBTitle: cryo-em structure of idle yeast ssh1 complex bound to the2 yeast 80s ribosome 66 d2evra2 not modelled 7.3 17 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:NlpC/P60 67 d1w44a_ not modelled 7.1 23 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 68 c3cdxB_ not modelled 7.1 57 PDB header:hydrolase Chain: B: PDB Molecule:succinylglutamatedesuccinylase/aspartoacylase; PDBTitle: crystal structure of2 succinylglutamatedesuccinylase/aspartoacylase from3 rhodobacter sphaeroides 69 c3cmwA_ not modelled 7.1 18 PDB header:recombination/dna Chain: A: PDB Molecule:protein reca; PDBTitle: mechanism of homologous recombination from the reca-2 ssdna/dsdna structures 70 d2fqla1 not modelled 7.1 29 Fold:N domain of copper amine oxidase-like Superfamily:Frataxin/Nqo15-like Family:Frataxin-like 71 d1li4a2 not modelled 7.0 21 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:S-adenosylhomocystein hydrolase 72 d2hs5a1 not modelled 7.0 15 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:GntR-like transcriptional regulators 73 d1ew4a_ not modelled 7.0 21 Fold:N domain of copper amine oxidase-like Superfamily:Frataxin/Nqo15-like Family:Frataxin-like 74 d1awda_ not modelled 7.0 30 Fold:beta-Grasp (ubiquitin-like) Superfamily:2Fe-2S ferredoxin-like Family:2Fe-2S ferredoxin-related 75 c1od4C_ not modelled 6.9 8 PDB header:ligase Chain: C: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: acetyl-coa carboxylase carboxyltransferase domain 76 c1x0uB_ not modelled 6.9 10 PDB header:lyase Chain: B: PDB Molecule:hypothetical methylmalonyl-coa decarboxylase alpha subunit; PDBTitle: crystal structure of the carboxyl transferase subunit of putative pcc2 of sulfolobus tokodaii 77 c3f3bA_ not modelled 6.8 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phage-like element pbsx protein xkdh; PDBTitle: structure of the phage-like element pbsx protein xkdh from2 bacillus subtilus. northeast structural genomics3 consortium target sr352. 78 c3jtoE_ not modelled 6.8 21 PDB header:protein binding Chain: E: PDB Molecule:adapter protein meca 2; PDBTitle: crystal structure of the c-terminal domain of ypbh 79 c3mk3L_ not modelled 6.8 15 PDB header:transferase Chain: L: PDB Molecule:6,7-dimethyl-8-ribityllumazine synthase; PDBTitle: crystal structure of lumazine synthase from salmonella typhimurium lt2 80 d2ac7a1 not modelled 6.7 12 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 81 c3a2kB_ not modelled 6.7 18 PDB header:ligase/rna Chain: B: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils complexed with trna 82 d1sp8a2 not modelled 6.7 15 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family:Extradiol dioxygenases 83 d1sbza_ not modelled 6.7 18 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 84 d2aeba1 not modelled 6.5 28 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 85 c2v6uB_ not modelled 6.5 23 PDB header:lyase Chain: B: PDB Molecule:pterin-4a-carbinolamine dehydratase; PDBTitle: high resolution crystal structure of pterin-4a-2 carbinolamine dehydratase from toxoplasma gondii 86 c3gt2A_ not modelled 6.5 16 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the p60 domain from m. avium2 paratuberculosis antigen map1272c 87 d1ni5a1 not modelled 6.4 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PP-loop ATPase 88 d1ws6a1 not modelled 6.3 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 89 c2crcA_ not modelled 6.1 83 PDB header:ligase Chain: A: PDB Molecule:ubiquitin conjugating enzyme 7 interacting PDBTitle: solution structure of the zf-ranbp domain of the protein2 hbv associated factor 90 d1usma_ not modelled 6.0 18 Fold:DCoH-like Superfamily:PCD-like Family:PCD-like 91 c2vs1A_ not modelled 5.9 24 PDB header:transferase Chain: A: PDB Molecule:uncharacterized rna methyltransferase pyrab10780; PDBTitle: the crystal structure of pyrococcus abyssi trna (uracil-54,2 c5)-methyltransferase in complex with s-adenosyl-l-3 homocysteine 92 c2kmfA_ not modelled 5.9 31 PDB header:photosynthesis Chain: A: PDB Molecule:photosystem ii 11 kda protein; PDBTitle: solution structure of psb27 from cyanobacterial photosystem2 ii 93 d1wdva_ not modelled 5.9 10 Fold:YbaK/ProRS associated domain Superfamily:YbaK/ProRS associated domain Family:YbaK/ProRS associated domain 94 d2ceva_ not modelled 5.9 28 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 95 c2nvgA_ not modelled 5.8 10 PDB header:oxidoreductase Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit; PDBTitle: soluble domain of rieske iron sulfur protein. 96 c2vroB_ not modelled 5.8 14 PDB header:oxidoreductase Chain: B: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from2 burkholderia xenovorans lb400 97 c1hvwA_ not modelled 5.7 67 PDB header:toxin Chain: A: PDB Molecule:omega-atracotoxin-hv1a; PDBTitle: hairpinless mutant of omega-atracotoxin-hv1a 98 d1hvwa_ not modelled 5.7 67 Fold:Knottins (small inhibitors, toxins, lectins) Superfamily:omega toxin-like Family:Spider toxins 99 d2a7sa1 not modelled 5.7 8 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0