Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	R	T	D	E	L	R	T	A	R	I	E	S	L	V	T	P	A	E	L	A	L	R	Y	P	V	T	P	G	V	A	T	H	V	T	D	S	R	R	R	I	E	K	I	L	N	G	E	D	K	R	L	L	V	I	I	G	P	C
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?			?	?	?	?	?	?	?	?										?																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	I	H	D	L	T	A	A	M	E	Y	A	T	R	L	Q	S	L	R	N	Q	Y	Q	S	R	L	E	I	V	M	R	T	Y	F	E	K	P	R	T	V	V	G	W	K	G	L	I	S	D	P	D	L	N	G	S	Y	R	V	N	H
Secondary structure
SS confidence
Disorder																								?																													?		?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	L	E	L	A	R	K	L	L	L	Q	V	N	E	L	G	V	P	T	A	T	E	F	L	D	M	V	T	G	Q	F	I	A	D	L	I	S	W	G	A	I	G	A	R	T	T	E	S	Q	I	H	R	E	M	A	S	A	L	S	C
Secondary structure
SS confidence
Disorder																																															?				?	?					?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		P	V	G	F	K	N	G	T	D	G	N	T	R	I	A	V	D	A	I	R	A	A	R	A	S	H	M	F	L	S	P	D	K	N	G	Q	M	T	I	Y	Q	T	S	G	N	P	Y	G	H	I	I	M	R	G	G	K	K	P	N	Y
Secondary structure
SS confidence
Disorder													?																																													?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		H	A	D	D	I	A	A	A	C	D	T	L	H	E	F	D	L	P	E	H	L	V	V	D	F	S	H	G	N	C	Q	K	Q	H	R	R	Q	L	E	V	C	E	D	I	C	Q	Q	I	R	N	G	S	T	A	I	A	G	I	M	A
Secondary structure
SS confidence
Disorder																?		?													?	?	?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.
Sequence		E	S	F	L	R	E	G	T	Q	K	I	V	G	S	Q	P	L	T	Y	G	Q	S	I	T	D	P	C	L	G	W	E	D	T	E	R	L	V	E	K	L	A	S	A	V	D	T	R	F
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?	?	?												?																	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1n8f chain A Region: 7 - 347 Aligned: 341 Modelled: 341 Confidence: 100.0% Identity: 57% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 3tqk chain A Region: 8 - 347 Aligned: 338 Modelled: 340 Confidence: 100.0% Identity: 46% PDB header:transferase Chain: A: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: structure of phospho-2-dehydro-3-deoxyheptonate aldolase from2 francisella tularensis schu s4 Phyre2 PDB 1of8 chain A Region: 7 - 347 Aligned: 334 Modelled: 341 Confidence: 100.0% Identity: 51% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 1ofa chain B Region: 7 - 347 Aligned: 332 Modelled: 341 Confidence: 100.0% Identity: 51% PDB header:lyase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: crystal structure of the tyrosine-regulated2 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase3 from saccharomyces cerevisiae in complex with4 phosphoenolpyruvate and cobalt(ii) Phyre2 PDB 1vr6 chain A domain 1 Region: 6 - 348 Aligned: 289 Modelled: 309 Confidence: 100.0% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 1vs1 chain B Region: 42 - 340 Aligned: 241 Modelled: 274 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep Phyre2 PDB 1zco chain A Region: 42 - 347 Aligned: 246 Modelled: 281 Confidence: 100.0% Identity: 24% PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase; PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase Phyre2 PDB 2a21 chain A domain 1 Region: 51 - 343 Aligned: 245 Modelled: 275 Confidence: 100.0% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 3nvt chain A Region: 42 - 343 Aligned: 244 Modelled: 277 Confidence: 100.0% Identity: 19% PDB header:transferase/isomerase Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e Phyre2 PDB 3stg chain A Region: 42 - 347 Aligned: 249 Modelled: 263 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis Phyre2 PDB 3fs2 chain A Region: 42 - 340 Aligned: 240 Modelled: 273 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate2 aldolase from bruciella melitensis at 1.85a resolution Phyre2 PDB 1d9e chain A Region: 42 - 347 Aligned: 251 Modelled: 274 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 1o60 chain A Region: 42 - 346 Aligned: 257 Modelled: 286 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 3sz8 chain D Region: 48 - 347 Aligned: 244 Modelled: 281 Confidence: 100.0% Identity: 14% PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei Phyre2 PDB 3t4c chain D Region: 42 - 346 Aligned: 249 Modelled: 277 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria Phyre2 PDB 3pg8 chain B Region: 42 - 348 Aligned: 241 Modelled: 262 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima Phyre2 PDB 2zdr chain A domain 2 Region: 42 - 343 Aligned: 247 Modelled: 267 Confidence: 99.4% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: NeuB-like Phyre2 PDB 1vli chain A domain 2 Region: 42 - 346 Aligned: 246 Modelled: 286 Confidence: 99.1% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: NeuB-like Phyre2 PDB 1xuz chain A Region: 42 - 346 Aligned: 248 Modelled: 265 Confidence: 98.7% Identity: 15% PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol Phyre2 PDB 2b7o chain A domain 1 Region: 158 - 346 Aligned: 163 Modelled: 188 Confidence: 98.1% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class-II DAHP synthetase Phyre2 1 d1n8fa_ 2 c3tqkA_ 3 d1of8a_ 4 c1ofaB_ 5 d1vr6a1 6 c1vs1B_ 7 c1zcoA_ 8 d2a21a1 9 c3nvtA_ 10 c3stgA_ 11 c3fs2A_ 12 d1d9ea_ 13 d1o60a_ 14 c3sz8D_ 15 c3t4cD_ 16 c3pg8B_ 17 d2zdra2 18 d1vlia2 19 c1xuzA_ 20 d2b7oa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1n8fa_ 100.0 57 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 2 c3tqkA_ 100.0 46 PDB header:transferase Chain: A: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: structure of phospho-2-dehydro-3-deoxyheptonate aldolase from2 francisella tularensis schu s4 3 d1of8a_ 100.0 51 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 4 c1ofaB_ 100.0 51 PDB header:lyase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: crystal structure of the tyrosine-regulated2 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase3 from saccharomyces cerevisiae in complex with4 phosphoenolpyruvate and cobalt(ii) 5 d1vr6a1 100.0 22 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 6 c1vs1B_ 100.0 24 PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep 7 c1zcoA_ 100.0 24 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase; PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase 8 d2a21a1 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 9 c3nvtA_ 100.0 19 PDB header:transferase/isomerase Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e 10 c3stgA_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis 11 c3fs2A_ 100.0 22 PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate2 aldolase from bruciella melitensis at 1.85a resolution 12 d1d9ea_ 100.0 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 13 d1o60a_ 100.0 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 14 c3sz8D_ 100.0 14 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei 15 c3t4cD_ 100.0 18 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria 16 c3pg8B_ 100.0 24 PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima 17 d2zdra2 99.4 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 18 d1vlia2 99.1 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 19 c1xuzA_ 98.7 15 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 20 d2b7oa1 98.1 23 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class-II DAHP synthetase 21 c1vliA_ not modelled 98.0 15 PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution 22 c3g8rA_ not modelled 97.5 13 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 23 d1ajza_ not modelled 93.7 17 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 24 d1ad1a_ not modelled 93.5 10 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 25 c2y5sA_ not modelled 86.6 19 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of burkholderia cenocepacia dihydropteroate2 synthase complexed with 7,8-dihydropteroate. 26 c3eb2A_ not modelled 84.2 12 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 27 d1dxha1 not modelled 82.5 22 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 28 c2otcA_ not modelled 79.8 18 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine 29 c3tr9A_ not modelled 79.2 17 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii 30 c1ortD_ not modelled 76.3 21 PDB header:transferase Chain: D: PDB Molecule:ornithine transcarbamoylase; PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa 31 c1tx2A_ not modelled 74.6 15 PDB header:transferase Chain: A: PDB Molecule:dhps, dihydropteroate synthase; PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis 32 d1tx2a_ not modelled 74.6 15 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 33 c1ml4A_ not modelled 71.2 24 PDB header:transferase Chain: A: PDB Molecule:aspartate transcarbamoylase; PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi 34 d1sq5a_ not modelled 70.8 18 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Phosphoribulokinase/pantothenate kinase 35 c3updA_ not modelled 69.7 21 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus 36 d1duvg1 not modelled 69.0 22 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 37 c2vqqA_ not modelled 64.7 18 PDB header:hydrolase Chain: A: PDB Molecule:histone deacetylase 4; PDBTitle: structure of hdac4 catalytic domain (a double cysteine-to-2 alanine mutant) bound to a trifluoromethylketone inhbitor 38 d1eyea_ not modelled 64.6 12 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 39 c3d6nB_ not modelled 63.8 20 PDB header:hydrolase/transferase Chain: B: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase 40 c3tqcB_ not modelled 60.0 14 PDB header:transferase Chain: B: PDB Molecule:pantothenate kinase; PDBTitle: structure of the pantothenate kinase (coaa) from coxiella burnetii 41 c3e5bB_ not modelled 59.6 23 PDB header:lyase Chain: B: PDB Molecule:isocitrate lyase; PDBTitle: 2.4 a crystal structure of isocitrate lyase from brucella2 melitensis 42 d1vlva1 not modelled 57.9 16 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 43 d1f74a_ not modelled 57.0 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 44 d1ml4a1 not modelled 56.8 24 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 45 d1otha1 not modelled 56.3 22 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 46 c2p2gD_ not modelled 56.2 28 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form 47 c2e3zB_ not modelled 56.1 16 PDB header:hydrolase Chain: B: PDB Molecule:beta-glucosidase; PDBTitle: crystal structure of intracellular family 1 beta-2 glucosidase bgl1a from the basidiomycete phanerochaete3 chrysosporium in substrate-free form 48 c3gd5D_ not modelled 54.3 23 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus 49 c1a1sA_ not modelled 52.5 21 PDB header:transcarbamylase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus 50 c3si9B_ not modelled 50.9 17 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from bartonella2 henselae 51 d1o5ka_ not modelled 49.8 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 52 d1pvva1 not modelled 49.7 20 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 53 c3grfA_ not modelled 47.8 22 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia 54 c1vlvA_ not modelled 47.2 15 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution 55 c2ze5A_ not modelled 47.1 25 PDB header:transferase Chain: A: PDB Molecule:isopentenyl transferase; PDBTitle: crystal structure of adenosine phosphate-isopentenyltransferase 56 c3bi8A_ not modelled 47.0 16 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of dihydrodipicolinate synthase from clostridium2 botulinum 57 c3ptkB_ not modelled 46.2 18 PDB header:hydrolase Chain: B: PDB Molecule:beta-glucosidase os4bglu12; PDBTitle: the crystal structure of rice (oryza sativa l.) os4bglu12 58 c2w37A_ not modelled 45.5 21 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic; PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii 59 c3pueA_ not modelled 44.8 18 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution 60 c1fvoB_ not modelled 44.5 22 PDB header:transferase Chain: B: PDB Molecule:ornithine transcarbamylase; PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate 61 d1tuga1 not modelled 43.8 19 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 62 c2ef0A_ not modelled 41.3 26 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus 63 c2hjpA_ not modelled 40.3 17 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 64 d2e1da1 not modelled 38.6 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 65 c2p2sA_ not modelled 38.1 22 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase (yp_050235.1) from2 erwinia carotovora atroseptica scri1043 at 1.25 a resolution 66 c3a8tA_ not modelled 37.6 19 PDB header:transferase Chain: A: PDB Molecule:adenylate isopentenyltransferase; PDBTitle: plant adenylate isopentenyltransferase in complex with atp 67 c3ahyD_ not modelled 36.9 10 PDB header:hydrolase Chain: D: PDB Molecule:beta-glucosidase; PDBTitle: crystal structure of beta-glucosidase 2 from fungus trichoderma reesei2 in complex with tris 68 c2ehhE_ not modelled 36.3 19 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 69 c3noeA_ not modelled 36.0 17 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa 70 c3daqB_ not modelled 35.3 15 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus 71 c2bmbA_ not modelled 35.1 15 PDB header:transferase Chain: A: PDB Molecule:folic acid synthesis protein fol1; PDBTitle: x-ray structure of the bifunctional 6-hydroxymethyl-7,8-2 dihydroxypterin pyrophosphokinase dihydropteroate synthase3 from saccharomyces cerevisiae 72 c3cprB_ not modelled 33.6 18 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 73 d2v3za1 not modelled 33.4 21 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 74 d1u1ia1 not modelled 33.0 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 75 d1igwa_ not modelled 33.0 23 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 76 c3b4uB_ not modelled 32.0 7 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58 77 d2v89a1 not modelled 31.5 21 Fold:FYVE/PHD zinc finger Superfamily:FYVE/PHD zinc finger Family:PHD domain 78 c3d3qB_ not modelled 29.1 28 PDB header:transferase Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of trna delta(2)-isopentenylpyrophosphate2 transferase (se0981) from staphylococcus epidermidis.3 northeast structural genomics consortium target ser100 79 d1pffa_ not modelled 29.1 25 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 80 c2jf7B_ not modelled 28.7 13 PDB header:hydrolase Chain: B: PDB Molecule:strictosidine-o-beta-d-glucosidase; PDBTitle: structure of strictosidine glucosidase 81 c2yxgD_ not modelled 28.3 19 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihyrodipicolinate synthase (dapa) 82 d1ulza3 not modelled 28.3 11 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 83 c3u57A_ not modelled 28.0 16 PDB header:hydrolase Chain: A: PDB Molecule:raucaffricine-o-beta-d-glucosidase; PDBTitle: structures of alkaloid biosynthetic glucosidases decode substrate2 specificity 84 c1h6dL_ not modelled 27.8 18 PDB header:protein translocation Chain: L: PDB Molecule:precursor form of glucose-fructose PDBTitle: oxidized precursor form of glucose-fructose oxidoreductase2 from zymomonas mobilis complexed with glycerol 85 c3exaD_ not modelled 27.1 28 PDB header:transferase Chain: D: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of the full-length trna2 isopentenylpyrophosphate transferase (bh2366) from3 bacillus halodurans, northeast structural genomics4 consortium target bhr41. 86 c2qt7B_ not modelled 26.9 36 PDB header:hydrolase Chain: B: PDB Molecule:receptor-type tyrosine-protein phosphatase-like PDBTitle: crystallographic structure of the mature ectodomain of the2 human receptor-type protein-tyrosine phosphatase ia-2 at3 1.30 angstroms 87 c1v02F_ not modelled 26.8 21 PDB header:hydrolase Chain: F: PDB Molecule:dhurrinase; PDBTitle: crystal structure of the sorghum bicolor dhurrinase 1 88 d1v02a_ not modelled 26.8 21 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Family 1 of glycosyl hydrolase 89 c3fluD_ not modelled 26.6 18 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis 90 c3oqbF_ not modelled 26.0 20 PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase from bradyrhizobium2 japonicum usda 110 91 c3na8A_ not modelled 25.4 13 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of a putative dihydrodipicolinate synthetase from2 pseudomonas aeruginosa 92 c2ixaA_ not modelled 24.4 15 PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase; PDBTitle: a-zyme, n-acetylgalactosaminidase 93 d2auwa1 not modelled 24.4 75 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:NE0471 C-terminal domain-like 94 c2h9aA_ not modelled 24.3 20 PDB header:oxidoreductase Chain: A: PDB Molecule:carbon monoxide dehydrogenase corrinoid/iron- PDBTitle: corrinoid iron-sulfur protein 95 c1ofgF_ not modelled 24.3 19 PDB header:oxidoreductase Chain: F: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: glucose-fructose oxidoreductase 96 c3btuD_ not modelled 23.0 18 PDB header:transcription Chain: D: PDB Molecule:galactose/lactose metabolism regulatory protein PDBTitle: crystal structure of the super-repressor mutant of gal80p2 from saccharomyces cerevisiae; gal80(s2) [e351k] 97 c2wamB_ not modelled 22.6 13 PDB header:unknown function Chain: B: PDB Molecule:conserved hypothetical alanine and leucine rich PDBTitle: crystal structure of mycobacterium tuberculosis unknown2 function protein rv2714 98 c2auwB_ not modelled 22.5 75 PDB header:unknown function Chain: B: PDB Molecule:hypothetical protein ne0471; PDBTitle: crystal structure of putative dna binding protein ne0471 from2 nitrosomonas europaea atcc 19718 99 d1ryda1 not modelled 21.9 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 100 c3crqA_ not modelled 21.8 24 PDB header:transferase Chain: A: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: structure of trna dimethylallyltransferase: rna2 modification through a channel 101 c3cdzB_ not modelled 21.7 10 PDB header:blood clotting Chain: B: PDB Molecule:coagulation factor viii light chain; PDBTitle: crystal structure of human factor viii 102 c3g0sA_ not modelled 21.7 16 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 103 c3fhlC_ not modelled 21.4 20 PDB header:oxidoreductase Chain: C: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase from bacteroides2 fragilis nctc 9343 104 c3fa4D_ not modelled 21.4 13 PDB header:lyase Chain: D: PDB Molecule:2,3-dimethylmalate lyase; PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form 105 d1ydwa1 not modelled 21.2 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 106 c3fozB_ not modelled 21.1 20 PDB header:transferase/rna Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate transferase; PDBTitle: structure of e. coli isopentenyl-trna transferase in complex with e.2 coli trna(phe) 107 d1f05a_ not modelled 20.6 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 108 c3m16A_ not modelled 20.4 14 PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: structure of a transaldolase from oleispira antarctica

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0