Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0C0V0
DateThu Jan 5 11:30:02 GMT 2012
Unique Job ID39500de3398df43d

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c4a8aI_
Top template information
PDB header:hydrolase/hydrolase
Chain: I: PDB Molecule:periplasmic ph-dependent serine endoprotease degq;
PDBTitle: asymmetric cryo-em reconstruction of e. coli degq 12-mer in complex2 with lysozyme
Confidence and coverage
Confidence:100.0% Coverage: 81%
385 residues ( 81% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPMLEKVMPSVVSINVEGS
Secondary structure 
SS confidence 
Disorder  ?????
??????????????????????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  TTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGNGGGQQQKFMALGSGVIID
Secondary structure 
SS confidence 
Disorder 
?????????????
???????????????????????????????????????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  ADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRSDIALIQIQNPKNLTAIKMAD
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  SDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNAENYENFIQTDAAINRGNSGGAL
Secondary structure 
SS confidence 
Disorder 
?????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  VNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNLTSQMVEYGQVKRGELGIMGTELNS
Secondary structure 
SS confidence 
Disorder 
???????
?
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  ELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGDVITSLNGKPISSFAALRAQVGTMPVG
Secondary structure 
SS confidence 
Disorder 
?
????
????
?
???
????
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  SKLTLGLLRDGKQVNVNLELQQSSQNQVDSSSIFNGIEGAEMSNKGKDQGVVVNNVKTGT
Secondary structure 
SS confidence 
Disorder 
???????????????????????????
????
Disorder confidence 
 
   .........430.........440.........450.........460.........470....
Sequence  PAAQIGLKKGDVIIGANQQAVKNIAELRKVLDSKPSVLALNIQRGDSTIYLLMQ
Secondary structure 
SS confidence 
Disorder 
??
?
?
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 4a8a chain I

3D model

Region: 37 - 474
Aligned: 385
Modelled: 392
Confidence: 100.0%
Identity: 62%
PDB header:hydrolase/hydrolase
Chain: I: PDB Molecule:periplasmic ph-dependent serine endoprotease degq;
PDBTitle: asymmetric cryo-em reconstruction of e. coli degq 12-mer in complex2 with lysozyme

Phyre2

PDB 3pv5 chain B

3D model

Region: 39 - 473
Aligned: 374
Modelled: 389
Confidence: 100.0%
Identity: 46%
PDB header:hydrolase
Chain: B: PDB Molecule:degq;
PDBTitle: structure of legionella fallonii degq (n189g/p190g variant)

Phyre2

PDB 3stj chain C

3D model

Region: 37 - 383
Aligned: 300
Modelled: 300
Confidence: 100.0%
Identity: 70%
PDB header:hydrolase
Chain: C: PDB Molecule:protease degq;
PDBTitle: crystal structure of the protease + pdz1 domain of degq from2 escherichia coli

Phyre2

PDB 1ky9 chain A

3D model

Region: 37 - 379
Aligned: 311
Modelled: 310
Confidence: 100.0%
Identity: 94%
PDB header:hydrolase
Chain: A: PDB Molecule:protease do;
PDBTitle: crystal structure of degp (htra)

Phyre2

PDB 3pv4 chain A

3D model

Region: 38 - 382
Aligned: 280
Modelled: 301
Confidence: 100.0%
Identity: 52%
PDB header:hydrolase
Chain: A: PDB Molecule:degq;
PDBTitle: structure of legionella fallonii degq (delta-pdz2 variant)

Phyre2

PDB 3gds chain A

3D model

Region: 33 - 379
Aligned: 291
Modelled: 307
Confidence: 100.0%
Identity: 41%
PDB header:hydrolase/hydrolase activator
Chain: A: PDB Molecule:protease degs;
PDBTitle: crystal structure of degs h198p/d320a mutant modified by dfp in2 complex with dnrdgnvyyf peptide

Phyre2

PDB 3qo6 chain B

3D model

Region: 31 - 386
Aligned: 313
Modelled: 319
Confidence: 100.0%
Identity: 36%
PDB header:photosynthesis
Chain: B: PDB Molecule:protease do-like 1, chloroplastic;
PDBTitle: crystal structure analysis of the plant protease deg1

Phyre2

PDB 1lcy chain A

3D model

Region: 30 - 384
Aligned: 290
Modelled: 314
Confidence: 100.0%
Identity: 34%
PDB header:hydrolase
Chain: A: PDB Molecule:htra2 serine protease;
PDBTitle: crystal structure of the mitochondrial serine protease htra2

Phyre2

PDB 2z9i chain B

3D model

Region: 37 - 374
Aligned: 267
Modelled: 272
Confidence: 100.0%
Identity: 45%
PDB header:hydrolase
Chain: B: PDB Molecule:probable serine protease pepd;
PDBTitle: crystal structure of rv0983 from mycobacterium tuberculosis-2 proteolytically active form

Phyre2

PDB 2r3y chain C

3D model

Region: 37 - 384
Aligned: 271
Modelled: 285
Confidence: 100.0%
Identity: 44%
PDB header:hydrolase/hydrolase activator
Chain: C: PDB Molecule:protease degs;
PDBTitle: crystal structure of the degs protease in complex with the2 ywf activating peptide

Phyre2

PDB 1ky9 chain A domain 2

3D model

Region: 37 - 285
Aligned: 217
Modelled: 222
Confidence: 100.0%
Identity: 98%
Fold: Trypsin-like serine proteases
Superfamily: Trypsin-like serine proteases
Family: Prokaryotic proteases

Phyre2

PDB 1l1j chain A

3D model

Region: 39 - 280
Aligned: 217
Modelled: 219
Confidence: 100.0%
Identity: 44%
Fold: Trypsin-like serine proteases
Superfamily: Trypsin-like serine proteases
Family: Prokaryotic proteases

Phyre2

PDB 2rce chain I

3D model

Region: 33 - 283
Aligned: 195
Modelled: 205
Confidence: 100.0%
Identity: 44%
PDB header:hydrolase
Chain: I: PDB Molecule:protease degs;
PDBTitle: dfp modified degs delta pdz

Phyre2

PDB 3sti chain C

3D model

Region: 37 - 283
Aligned: 183
Modelled: 192
Confidence: 100.0%
Identity: 75%
PDB header:hydrolase
Chain: C: PDB Molecule:protease degq;
PDBTitle: crystal structure of the protease domain of degq from escherichia coli

Phyre2

PDB 2qf3 chain A domain 1

3D model

Region: 37 - 284
Aligned: 189
Modelled: 204
Confidence: 100.0%
Identity: 51%
Fold: Trypsin-like serine proteases
Superfamily: Trypsin-like serine proteases
Family: Prokaryotic proteases

Phyre2

PDB 3nzi chain A

3D model

Region: 41 - 283
Aligned: 196
Modelled: 202
Confidence: 100.0%
Identity: 46%
PDB header:hydrolase/hydrolase substrate
Chain: A: PDB Molecule:serine protease htra1;
PDBTitle: substrate induced remodeling of the active site regulates htra12 activity

Phyre2

PDB 2z9i chain A domain 2

3D model

Region: 40 - 285
Aligned: 192
Modelled: 194
Confidence: 100.0%
Identity: 47%
Fold: Trypsin-like serine proteases
Superfamily: Trypsin-like serine proteases
Family: Prokaryotic proteases

Phyre2

PDB 1lcy chain A domain 2

3D model

Region: 30 - 277
Aligned: 195
Modelled: 207
Confidence: 100.0%
Identity: 42%
Fold: Trypsin-like serine proteases
Superfamily: Trypsin-like serine proteases
Family: Prokaryotic proteases

Phyre2

PDB 3nwu chain B

3D model

Region: 31 - 277
Aligned: 182
Modelled: 198
Confidence: 100.0%
Identity: 48%
PDB header:hydrolase
Chain: B: PDB Molecule:serine protease htra1;
PDBTitle: substrate induced remodeling of the active site regulates htra12 activity

Phyre2

PDB 3k6z chain A

3D model

Region: 31 - 280
Aligned: 189
Modelled: 197
Confidence: 100.0%
Identity: 26%
PDB header:hydrolase
Chain: A: PDB Molecule:possible membrane-associated serine protease;
PDBTitle: crystal structure of rv3671c protease, inactive form

Phyre2
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c4a8aI_
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c3pv5B_
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c3stjC_
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c1ky9A_
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c3pv4A_
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c3gdsA_
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c3qo6B_
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c1lcyA_
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c2z9iB_
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c2r3yC_
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d1ky9a2
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d1l1ja_
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c2rceI_
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c3stiC_
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d2qf3a1
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c3nziA_
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d2z9ia2
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d1lcya2
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c3nwuB_
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c3k6zA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c4a8aI_
100.0 62 PDB header:hydrolase/hydrolase
Chain: I: PDB Molecule:periplasmic ph-dependent serine endoprotease degq;
PDBTitle: asymmetric cryo-em reconstruction of e. coli degq 12-mer in complex2 with lysozyme
2c3pv5B_
100.0 46 PDB header:hydrolase
Chain: B: PDB Molecule:degq;
PDBTitle: structure of legionella fallonii degq (n189g/p190g variant)
3c3stjC_
100.0 70 PDB header:hydrolase
Chain: C: PDB Molecule:protease degq;
PDBTitle: crystal structure of the protease + pdz1 domain of degq from2 escherichia coli
4c1ky9A_
100.0 94 PDB header:hydrolase
Chain: A: PDB Molecule:protease do;
PDBTitle: crystal structure of degp (htra)
5c3pv4A_
100.0 52 PDB header:hydrolase
Chain: A: PDB Molecule:degq;
PDBTitle: structure of legionella fallonii degq (delta-pdz2 variant)
6c3gdsA_
100.0 41 PDB header:hydrolase/hydrolase activator
Chain: A: PDB Molecule:protease degs;
PDBTitle: crystal structure of degs h198p/d320a mutant modified by dfp in2 complex with dnrdgnvyyf peptide
7c3qo6B_
100.0 36 PDB header:photosynthesis
Chain: B: PDB Molecule:protease do-like 1, chloroplastic;
PDBTitle: crystal structure analysis of the plant protease deg1
8c1lcyA_
100.0 34 PDB header:hydrolase
Chain: A: PDB Molecule:htra2 serine protease;
PDBTitle: crystal structure of the mitochondrial serine protease htra2
9c2z9iB_
100.0 45 PDB header:hydrolase
Chain: B: PDB Molecule:probable serine protease pepd;
PDBTitle: crystal structure of rv0983 from mycobacterium tuberculosis-2 proteolytically active form
10c2r3yC_
100.0 44 PDB header:hydrolase/hydrolase activator
Chain: C: PDB Molecule:protease degs;
PDBTitle: crystal structure of the degs protease in complex with the2 ywf activating peptide
11d1ky9a2
100.0 98 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
12d1l1ja_
100.0 44 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
13c2rceI_
100.0 44 PDB header:hydrolase
Chain: I: PDB Molecule:protease degs;
PDBTitle: dfp modified degs delta pdz
14c3stiC_
100.0 75 PDB header:hydrolase
Chain: C: PDB Molecule:protease degq;
PDBTitle: crystal structure of the protease domain of degq from escherichia coli
15d2qf3a1
100.0 51 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
16c3nziA_
100.0 46 PDB header:hydrolase/hydrolase substrate
Chain: A: PDB Molecule:serine protease htra1;
PDBTitle: substrate induced remodeling of the active site regulates htra12 activity
17d2z9ia2
100.0 47 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
18d1lcya2
100.0 42 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
19c3nwuB_
100.0 48 PDB header:hydrolase
Chain: B: PDB Molecule:serine protease htra1;
PDBTitle: substrate induced remodeling of the active site regulates htra12 activity
20c3k6zA_
100.0 26 PDB header:hydrolase
Chain: A: PDB Molecule:possible membrane-associated serine protease;
PDBTitle: crystal structure of rv3671c protease, inactive form
21c3mmgB_
not modelled 100.0 20 PDB header:viral protein, hydrolase
Chain: B: PDB Molecule:nuclear inclusion protein a;
PDBTitle: crystal structure of tobacco vein mottling virus protease
22c1zyoA_
not modelled 99.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:serine protease;
PDBTitle: crystal structure of the serine protease domain of sesbania mosaic2 virus polyprotein
23d1q31a_
not modelled 99.9 16 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Viral proteases
24c2w5eB_
not modelled 99.9 21 PDB header:hydrolase
Chain: B: PDB Molecule:putative serine protease;
PDBTitle: structural and biochemical analysis of human pathogenic2 astrovirus serine protease at 2.0 angstrom resolution
25d1lvmb_
not modelled 99.9 17 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Viral proteases
26d1qtfa_
not modelled 99.9 26 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
27c2qt5A_
not modelled 99.9 21 PDB header:peptide binding protein
Chain: A: PDB Molecule:glutamate receptor-interacting protein 1;
PDBTitle: crystal structure of grip1 pdz12 in complex with the fras12 peptide
28c2ka9A_
not modelled 99.9 20 PDB header:cell adhesion
Chain: A: PDB Molecule:disks large homolog 4;
PDBTitle: solution structure of psd-95 pdz12 complexed with cypin2 peptide
29c1p1dA_
not modelled 99.9 17 PDB header:protein binding
Chain: A: PDB Molecule:glutamate receptor interacting protein;
PDBTitle: structural insights into the inter-domain chaperoning of2 tandem pdz domains in glutamate receptor interacting3 proteins
30d1agja_
not modelled 99.9 26 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
31c3rleA_
not modelled 99.9 21 PDB header:membrane protein
Chain: A: PDB Molecule:golgi reassembly-stacking protein 2;
PDBTitle: crystal structure of grasp55 grasp domain (residues 7-208)
32c3r0hA_
not modelled 99.9 16 PDB header:peptide binding protein
Chain: A: PDB Molecule:inactivation-no-after-potential d protein;
PDBTitle: structure of inad pdz45 in complex with ng2 peptide
33c2vidA_
not modelled 99.9 20 PDB header:hydrolase
Chain: A: PDB Molecule:serine protease splb;
PDBTitle: serine protease splb from staphylococcus aureus at 1.8a2 resolution
34c2xkxB_
not modelled 99.9 20 PDB header:structural protein
Chain: B: PDB Molecule:disks large homolog 4;
PDBTitle: single particle analysis of psd-95 in negative stain
35c1u3bA_
not modelled 99.8 19 PDB header:protein transport
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding,
PDBTitle: auto-inhibition mechanism of x11s/mints family scaffold2 proteins revealed by the closed conformation of the tandem3 pdz domains
36c1w9qB_
not modelled 99.8 22 PDB header:cell adhesion
Chain: B: PDB Molecule:syntenin 1;
PDBTitle: crystal structure of the pdz tandem of human syntenin in2 complex with tnefaf peptide
37c2w7uC_
not modelled 99.8 21 PDB header:hydrolase
Chain: C: PDB Molecule:serine protease spla;
PDBTitle: spla serine protease of staphylococcus aureus (2.4a)
38c2as9B_
not modelled 99.8 21 PDB header:hydrolase
Chain: B: PDB Molecule:serine protease;
PDBTitle: functional and structural characterization of spl proteases2 from staphylococcus aureus
39c2b0fA_
not modelled 99.8 21 PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:picornain 3c (protease 3c) (p3c);
PDBTitle: nmr structure of the human rhinovirus 3c protease (serotype 14) with2 covalently bound ace-lealfq-ethylpropionate inhibitor
40d1cqqa_
not modelled 99.8 15 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Viral cysteine protease of trypsin fold
41d2qaaa1
not modelled 99.8 17 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
42d1l1na_
not modelled 99.8 16 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Viral cysteine protease of trypsin fold
43d2h5ca1
not modelled 99.7 17 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
44c2ouaA_
not modelled 99.7 17 PDB header:hydrolase
Chain: A: PDB Molecule:serine protease;
PDBTitle: crystal structure of nocardiopsis protease (napase)
45c2p3wB_
not modelled 99.7 28 PDB header:protein binding
Chain: B: PDB Molecule:probable serine protease htra3;
PDBTitle: crystal structure of the htra3 pdz domain bound to a phage-derived2 ligand (fgrwv)
46d1ky9a1
not modelled 99.7 97 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:HtrA-like serine proteases
47c2joaA_
not modelled 99.7 25 PDB header:protein binding
Chain: A: PDB Molecule:serine protease htra1;
PDBTitle: htra1 bound to an optimized peptide: nmr assignment of pdz2 domain and ligand resonances
48d1lcya1
not modelled 99.7 22 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:HtrA-like serine proteases
49c2o8lA_
not modelled 99.7 21 PDB header:hydrolase
Chain: A: PDB Molecule:v8 protease;
PDBTitle: structure of v8 protease from staphylococcus aureus
50d2o8la1
not modelled 99.7 21 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
51c1qy6A_
not modelled 99.7 21 PDB header:protease
Chain: A: PDB Molecule:serine protease;
PDBTitle: structue of v8 protease from staphylococcus aureus
52d2sfaa_
not modelled 99.7 17 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
53d2sgaa_
not modelled 99.6 17 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
54c2pfeA_
not modelled 99.6 18 PDB header:hydrolase
Chain: A: PDB Molecule:alkaline serine protease;
PDBTitle: crystal structure of thermobifida fusca protease a (tfpa)
55c1wczA_
not modelled 99.6 22 PDB header:hydrolase
Chain: A: PDB Molecule:glutamyl endopeptidase;
PDBTitle: crystal structure of an alkaline form of v8 protease from2 staphylococcus aureus
56d2z9ia1
not modelled 99.6 32 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:HtrA-like serine proteases
57c2ea3A_
not modelled 99.5 18 PDB header:hydrolase
Chain: A: PDB Molecule:chymotrypsin;
PDBTitle: crystal structure of cellulomonas bogoriensis chymotrypsin
58d1hpga_
not modelled 99.5 17 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
59c1z87A_
not modelled 99.5 14 PDB header:protein binding
Chain: A: PDB Molecule:alpha-1-syntrophin;
PDBTitle: solution structure of the split ph-pdz supramodule of alpha-2 syntrophin
60d1p3ca_
not modelled 99.5 15 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
61d1ky9b2
not modelled 99.5 99 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:HtrA-like serine proteases
62c2kl1A_
not modelled 99.4 28 PDB header:protein binding
Chain: A: PDB Molecule:ylbl protein;
PDBTitle: solution structure of gtr34c from geobacillus thermodenitrificans.2 northeast structural genomics consortium target gtr34c
63d1arba_
not modelled 99.4 12 Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Prokaryotic proteases
64d1ozia_
not modelled 99.4 17 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
65c2krgA_
not modelled 99.4 18 PDB header:signaling protein
Chain: A: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf1;
PDBTitle: solution structure of human sodium/ hydrogen exchange2 regulatory factor 1(150-358)
66c3i18A_
not modelled 99.4 22 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lmo2051 protein;
PDBTitle: crystal structure of the pdz domain of the sdrc-like protein2 (lmo2051) from listeria monocytogenes, northeast structural3 genomics consortium target lmr166b
67c3eggC_
not modelled 99.4 18 PDB header:hydrolase
Chain: C: PDB Molecule:spinophilin;
PDBTitle: crystal structure of a complex between protein phosphatase 1 alpha2 (pp1) and the pp1 binding and pdz domains of spinophilin
68d2i4sa1
not modelled 99.4 18 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:EpsC C-terminal domain-like
69d1p1da2
not modelled 99.4 19 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
70d1sota1
not modelled 99.3 34 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:HtrA-like serine proteases
71c2kjpA_
not modelled 99.3 32 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein ylbl;
PDBTitle: solution structure of protein ylbl (bsu15050) from bacillus2 subtilis, northeast structural genomics consortium target3 sr713a
72d1fc6a3
not modelled 99.3 22 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:Tail specific protease PDZ domain
73c2kjdA_
not modelled 99.3 18 PDB header:signaling protein
Chain: A: PDB Molecule:sodium/hydrogen exchange regulatory cofactor nhe-
PDBTitle: solution structure of extended pdz2 domain from nherf1 (150-2 270)
74c2jikB_
not modelled 99.3 21 PDB header:membrane protein
Chain: B: PDB Molecule:synaptojanin-2 binding protein;
PDBTitle: crystal structure of pdz domain of synaptojanin-2 binding2 protein
75c3diwB_
not modelled 99.3 24 PDB header:signaling protein/cell adhesion
Chain: B: PDB Molecule:tax1-binding protein 3;
PDBTitle: c-terminal beta-catenin bound tip-1 structure
76c2jilA_
not modelled 99.3 21 PDB header:membrane protein
Chain: A: PDB Molecule:glutamate receptor interacting protein-1;
PDBTitle: crystal structure of 2nd pdz domain of glutamate receptor2 interacting protein-1 (grip1)
77c3l4fD_
not modelled 99.3 19 PDB header:signaling protein/protein binding
Chain: D: PDB Molecule:sh3 and multiple ankyrin repeat domains protein
PDBTitle: crystal structure of betapix coiled-coil domain and shank2 pdz complex
78d1x5qa1
not modelled 99.3 27 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
79c2v90E_
not modelled 99.3 18 PDB header:protein-binding
Chain: E: PDB Molecule:pdz domain-containing protein 3;
PDBTitle: crystal structure of the 3rd pdz domain of intestine- and2 kidney-enriched pdz domain ikepp (pdzd3)
80d1um1a_
not modelled 99.3 20 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
81d2fe5a1
not modelled 99.3 16 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
82d1uhpa_
not modelled 99.3 25 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
83d1rgwa_
not modelled 99.3 18 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
84d1d5ga_
not modelled 99.3 17 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
85d1wfga_
not modelled 99.3 15 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
86d1wh1a_
not modelled 99.3 26 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
87c2iwnA_
not modelled 99.3 19 PDB header:signaling protein
Chain: A: PDB Molecule:multiple pdz domain protein;
PDBTitle: 3rd pdz domain of multiple pdz domain protein mpdz (casp2 target)
88d1t2ma1
not modelled 99.3 19 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
89d2byga1
not modelled 99.3 18 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
90d1q7xa_
not modelled 99.3 16 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
91d1m5za_
not modelled 99.3 22 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
92c2db5A_
not modelled 99.3 20 PDB header:protein binding
Chain: A: PDB Molecule:inad-like protein;
PDBTitle: solution structure of the first pdz domain of inad-like2 protein
93c3qglD_
not modelled 99.3 23 PDB header:protein binding
Chain: D: PDB Molecule:sorting nexin-27;
PDBTitle: crystal structure of pdz domain of sorting nexin 27 (snx27) in complex2 with the eseskv peptide corresponding to the c-terminal tail of girk3
94d2f0aa1
not modelled 99.3 24 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
95c2o2tB_
not modelled 99.3 28 PDB header:structural protein
Chain: B: PDB Molecule:multiple pdz domain protein;
PDBTitle: the crystal structure of the 1st pdz domain of mpdz
96d1ujda_
not modelled 99.3 15 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
97d1ry4a_
not modelled 99.3 20 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
98c2vwrA_
not modelled 99.3 21 PDB header:protein-binding
Chain: A: PDB Molecule:ligand of numb protein x 2;
PDBTitle: crystal structure of the second pdz domain of numb-binding2 protein 2
99d1ihja_
not modelled 99.3 21 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
100c2djtA_
not modelled 99.2 19 PDB header:signaling protein
Chain: A: PDB Molecule:unnamed protein product;
PDBTitle: solution structures of the pdz domain of human unnamed2 protein product
101d1wf8a1
not modelled 99.2 17 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
102c2ogpA_
not modelled 99.2 26 PDB header:signaling protein
Chain: A: PDB Molecule:partitioning-defective 3 homolog;
PDBTitle: solution structure of the second pdz domain of par-3
103c2q3gA_
not modelled 99.2 17 PDB header:structural genomics
Chain: A: PDB Molecule:pdz and lim domain protein 7;
PDBTitle: structure of the pdz domain of human pdlim7 bound to a c-2 terminal extension from human beta-tropomyosin
104d2hgaa1
not modelled 99.2 26 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:MTH1368 C-terminal domain-like
105d1whaa_
not modelled 99.2 22 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
106c2komA_
not modelled 99.2 24 PDB header:signaling protein
Chain: A: PDB Molecule:partitioning defective 3 homolog;
PDBTitle: solution structure of humar par-3b pdz2 (residues 451-549)
107d1q3oa_
not modelled 99.2 21 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
108c2gzvA_
not modelled 99.2 24 PDB header:signaling protein
Chain: A: PDB Molecule:prkca-binding protein;
PDBTitle: the cystal structure of the pdz domain of human pick1 (casp target)
109c3k1rA_
not modelled 99.2 16 PDB header:structural protein
Chain: A: PDB Molecule:harmonin;
PDBTitle: structure of harmonin npdz1 in complex with the sam-pbm of2 sans
110d1rzxa_
not modelled 99.2 18 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
111d2f5ya1
not modelled 99.2 28 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
112c2k1zA_
not modelled 99.2 22 PDB header:signaling protein
Chain: A: PDB Molecule:partitioning-defective 3 homolog;
PDBTitle: solution structure of par-3 pdz3
113c2fneB_
not modelled 99.2 22 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:multiple pdz domain protein;
PDBTitle: the crystal structure of the 13th pdz domain of mpdz
114c2v1wB_
not modelled 99.2 16 PDB header:structural protein
Chain: B: PDB Molecule:pdz and lim domain protein 4;
PDBTitle: crystal structure of human lim protein ril (pdlim4) pdz2 domain bound to the c-terminal peptide of human alpha-3 actinin-1
115c2iwoA_
not modelled 99.2 18 PDB header:signaling protein
Chain: A: PDB Molecule:multiple pdz domain protein;
PDBTitle: 12th pdz domain of multiple pdz domain protein mpdz (casp2 target)
116c2dm8A_
not modelled 99.2 20 PDB header:protein binding
Chain: A: PDB Molecule:inad-like protein;
PDBTitle: solution structure of the eighth pdz domain of human inad-2 like protein
117c2dazA_
not modelled 99.2 19 PDB header:protein binding
Chain: A: PDB Molecule:inad-like protein;
PDBTitle: solution structure of the 7th pdz domain of inad-like2 protein
118c2jreA_
not modelled 99.2 23 PDB header:de novo protein
Chain: A: PDB Molecule:c60-1 pdz domain peptide;
PDBTitle: c60-1, a pdz domain designed using statistical coupling2 analysis
119d1nf3c_
not modelled 99.2 17 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
120c2iwqA_
not modelled 99.2 15 PDB header:signaling protein
Chain: A: PDB Molecule:multiple pdz domain protein;
PDBTitle: 7th pdz domain of multiple pdz domain protein mpdz

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0