PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3nziA_

Fold library id	PDB Header	Molecule	Title
c3nziA_	PDB header: hydrolase/hydrolase substrate	Chain: A: PDB Molecule: serine protease htra1;	PDBTitle: substrate induced remodeling of the active site regulates htra12 activity

Links to external resources
Added to library: Sat Feb 26 08:49:02 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence E D P N S L R H K Y N F I A D V V E K I A P A V V H I E L F R K L P F S K R E V P V A S G S G F I V S E D G L I V T N A H V V T N K H R V K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
G G G
S S S S
S S S
S S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V E L K N G A T Y E A K I K D V D E K A D I A L I K I D H Q G K L P V L L L G R S S E L R P G E F V V A I G S P F S L Q N T V T T G I V S T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
B T T T T
S S
B
G G G
T T
G G G
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence T Q R G G K E L G L R N S D M D Y I Q T D A I I N Y G N S G G P L V N L D G E V I G I N T L K V T A G I S F A I P S D K I K K F L T E S H D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S
S
T T
T T
T T S
T T

.

Sequence R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	E	D	P	N	S	L	R	H	K	Y	N	F	I	A	D	V	V	E	K	I	A	P	A	V	V	H	I	E	L	F	R	K	L	P	F	S	K	R	E	V	P	V	A	S	G	S	G	F	I	V	S	E	D	G	L	I	V	T	N	A	H	V	V	T	N	K	H	R	V	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	S																G	G	G											S	S	S	S														S	S	S											S	S		S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	E	L	K	N	G	A	T	Y	E	A	K	I	K	D	V	D	E	K	A	D	I	A	L	I	K	I	D	H	Q	G	K	L	P	V	L	L	L	G	R	S	S	E	L	R	P	G	E	F	V	V	A	I	G	S	P	F	S	L	Q	N	T	V	T	T	G	I	V	S	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S	S					B							T	T	T	T									S	S							B			G	G	G			T	T									G	G	G		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	T	Q	R	G	G	K	E	L	G	L	R	N	S	D	M	D	Y	I	Q	T	D	A	I	I	N	Y	G	N	S	G	G	P	L	V	N	L	D	G	E	V	I	G	I	N	T	L	K	V	T	A	G	I	S	F	A	I	P	S	D	K	I	K	K	F	L	T	E	S	H	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T		S	S										S				T	T		T	T						T	T	S												T	T
	.
Sequence	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)