Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP24555
DateThu Jan 5 11:41:42 GMT 2012
Unique Job ID377270598b8dd693

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2xe4A_
Top template information
PDB header:hydrolase/inhibitor
Chain: A: PDB Molecule:oligopeptidase b;
PDBTitle: structure of oligopeptidase b from leishmania major
Confidence and coverage
Confidence:100.0% Coverage: 99%
678 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQENSYGHRVMASQQALQDR
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Disorder  ???????






















???


























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   .........70.........80.........90.........100.........110.........120
Sequence  ILKEIIDRIPQREVSAPYIKNGYRYRHIYEPGCEYAIYQRQSAFSEEWDEWETLLDANKR
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??????












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   .........130.........140.........150.........160.........170.........180
Sequence  AAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNLETGNWYPELLDNVEPSFVWA
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   .........190.........200.........210.........220.........230.........240
Sequence  NDSWIFYYVRKHPVTLLPYQVWRHAIGTPASQDKLIYEEKDDTYYVSLHKTTSKHYVVIH
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   .........250.........260.........270.........280.........290.........300
Sequence  LASATTSEVRLLDAEMADAEPFVFLPRRKDHEYSLDHYQHRFYLRSNRHGKNFGLYRTRM
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?

?








































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   .........310.........320.........330.........340.........350.........360
Sequence  RDEQQWEELIPPRENIMLEGFTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAY
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   .........370.........380.........390.........400.........410.........420
Sequence  VTWIAYNPEPETARLRYGYSSMTTPDTLFELDMDTGERRVLKQTEVPGFYAANYRSEHLW
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???

?









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   .........430.........440.........450.........460.........470.........480
Sequence  IVARDGVEVPVSLVYHRKHFRKGHNPLLVYGYGSYGASIDADFSFSRLSLLDRGFVYAIV
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?








































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   .........490.........500.........510.........520.........530.........540
Sequence  HVRGGGELGQQWYEDGKFLKKKNTFNDYLDACDALLKLGYGSPSLCYAMGGSAGGMLMGV
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Disorder 














??
??







































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   .........550.........560.........570.........580.........590.........600
Sequence  AINQRPELFHGVIAQVPFVDVVTTMLDESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDN
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   .........610.........620.........630.........640.........650.........660
Sequence  VTAQAYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDDHLLLLCTDMDSGHGGKSGRFK
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?????????


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   .........670.........680......
Sequence  SYEGVAMEYAFLVALAQGTLPATPAD
Secondary structure 










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Disorder 
















?
???????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2xe4 chain A

3D model

Region: 2 - 680
Aligned: 678
Modelled: 679
Confidence: 100.0%
Identity: 37%
PDB header:hydrolase/inhibitor
Chain: A: PDB Molecule:oligopeptidase b;
PDBTitle: structure of oligopeptidase b from leishmania major

Phyre2

PDB 1yr2 chain A

3D model

Region: 2 - 683
Aligned: 658
Modelled: 682
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase
Chain: A: PDB Molecule:prolyl oligopeptidase;
PDBTitle: structural and mechanistic analysis of two prolyl endopeptidases: role2 of inter-domain dynamics in catalysis and specificity

Phyre2

PDB 2bkl chain B

3D model

Region: 3 - 678
Aligned: 661
Modelled: 676
Confidence: 100.0%
Identity: 26%
PDB header:hydrolase
Chain: B: PDB Molecule:prolyl endopeptidase;
PDBTitle: structural and mechanistic analysis of two prolyl2 endopeptidases: role of inter-domain dynamics in3 catalysis and specificity

Phyre2

PDB 3ium chain A

3D model

Region: 2 - 683
Aligned: 659
Modelled: 667
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:prolyl endopeptidase;
PDBTitle: appep_wtx opened state

Phyre2

PDB 1qfm chain A

3D model

Region: 2 - 682
Aligned: 665
Modelled: 677
Confidence: 100.0%
Identity: 24%
PDB header:hydrolase
Chain: A: PDB Molecule:protein (prolyl oligopeptidase);
PDBTitle: prolyl oligopeptidase from porcine muscle

Phyre2

PDB 2ecf chain A

3D model

Region: 129 - 677
Aligned: 522
Modelled: 547
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase iv;
PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia

Phyre2

PDB 2g5t chain A

3D model

Region: 129 - 677
Aligned: 532
Modelled: 546
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag

Phyre2

PDB 2eep chain A

3D model

Region: 129 - 676
Aligned: 516
Modelled: 548
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative;
PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor

Phyre2

PDB 2qtb chain B

3D model

Region: 129 - 679
Aligned: 532
Modelled: 548
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: B: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor

Phyre2

PDB 1z68 chain A

3D model

Region: 62 - 677
Aligned: 586
Modelled: 612
Confidence: 100.0%
Identity: 16%
PDB header:lyase
Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit;
PDBTitle: crystal structure of human fibroblast activation protein alpha

Phyre2

PDB 3azq chain A

3D model

Region: 73 - 684
Aligned: 600
Modelled: 612
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase;
PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg

Phyre2

PDB 2hu7 chain A

3D model

Region: 112 - 678
Aligned: 530
Modelled: 559
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:acylamino-acid-releasing enzyme;
PDBTitle: binding of inhibitors by acylaminoacyl peptidase

Phyre2

PDB 1xfd chain D

3D model

Region: 103 - 678
Aligned: 552
Modelled: 569
Confidence: 100.0%
Identity: 13%
PDB header:membrane protein
Chain: D: PDB Molecule:dipeptidyl aminopeptidase-like protein 6;
PDBTitle: structure of a human a-type potassium channel accelerating factor2 dppx, a member of the dipeptidyl aminopeptidase family

Phyre2

PDB 1qfm chain A domain 1

3D model

Region: 2 - 409
Aligned: 397
Modelled: 408
Confidence: 100.0%
Identity: 19%
Fold: 7-bladed beta-propeller
Superfamily: Peptidase/esterase 'gauge' domain
Family: Prolyl oligopeptidase, N-terminal domain

Phyre2

PDB 1qfm chain A domain 2

3D model

Region: 410 - 682
Aligned: 269
Modelled: 273
Confidence: 100.0%
Identity: 29%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Prolyl oligopeptidase, C-terminal domain

Phyre2

PDB 3doi chain A

3D model

Region: 281 - 677
Aligned: 359
Modelled: 360
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:esterase;
PDBTitle: crystal structure of a thermostable esterase complex with2 paraoxon

Phyre2

PDB 2hu7 chain A domain 2

3D model

Region: 406 - 678
Aligned: 259
Modelled: 273
Confidence: 99.9%
Identity: 20%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Acylamino-acid-releasing enzyme, C-terminal donain

Phyre2

PDB 1orv chain A domain 2

3D model

Region: 414 - 679
Aligned: 255
Modelled: 266
Confidence: 99.9%
Identity: 16%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: DPP6 catalytic domain-like

Phyre2

PDB 2bgr chain A domain 2

3D model

Region: 414 - 679
Aligned: 255
Modelled: 266
Confidence: 99.9%
Identity: 15%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: DPP6 catalytic domain-like

Phyre2

PDB 3k2i chain A

3D model

Region: 309 - 680
Aligned: 350
Modelled: 372
Confidence: 99.9%
Identity: 11%
PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 4;
PDBTitle: human acyl-coenzyme a thioesterase 4

Phyre2
1

c2xe4A_
2

c1yr2A_
3

c2bklB_
4

c3iumA_
5

c1qfmA_
6

c2ecfA_
7

c2g5tA_
8

c2eepA_
9

c2qtbB_
10

c1z68A_
11

c3azqA_
12

c2hu7A_
13

c1xfdD_
14

d1qfma1
15

d1qfma2
16

c3doiA_
17

d2hu7a2
18

d1orva2
19

d2bgra2
20

c3k2iA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2xe4A_



100.0 37 PDB header:hydrolase/inhibitor
Chain: A: PDB Molecule:oligopeptidase b;
PDBTitle: structure of oligopeptidase b from leishmania major
2c1yr2A_



100.0 22 PDB header:hydrolase
Chain: A: PDB Molecule:prolyl oligopeptidase;
PDBTitle: structural and mechanistic analysis of two prolyl endopeptidases: role2 of inter-domain dynamics in catalysis and specificity
3c2bklB_



100.0 26 PDB header:hydrolase
Chain: B: PDB Molecule:prolyl endopeptidase;
PDBTitle: structural and mechanistic analysis of two prolyl2 endopeptidases: role of inter-domain dynamics in3 catalysis and specificity
4c3iumA_



100.0 23 PDB header:hydrolase
Chain: A: PDB Molecule:prolyl endopeptidase;
PDBTitle: appep_wtx opened state
5c1qfmA_



100.0 24 PDB header:hydrolase
Chain: A: PDB Molecule:protein (prolyl oligopeptidase);
PDBTitle: prolyl oligopeptidase from porcine muscle
6c2ecfA_



100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase iv;
PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia
7c2g5tA_



100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
8c2eepA_



100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative;
PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor
9c2qtbB_



100.0 15 PDB header:hydrolase
Chain: B: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor
10c1z68A_



100.0 16 PDB header:lyase
Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit;
PDBTitle: crystal structure of human fibroblast activation protein alpha
11c3azqA_



100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase;
PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg
12c2hu7A_



100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:acylamino-acid-releasing enzyme;
PDBTitle: binding of inhibitors by acylaminoacyl peptidase
13c1xfdD_



100.0 13 PDB header:membrane protein
Chain: D: PDB Molecule:dipeptidyl aminopeptidase-like protein 6;
PDBTitle: structure of a human a-type potassium channel accelerating factor2 dppx, a member of the dipeptidyl aminopeptidase family
14d1qfma1



100.0 19 Fold:7-bladed beta-propeller
Superfamily:Peptidase/esterase 'gauge' domain
Family:Prolyl oligopeptidase, N-terminal domain
15d1qfma2



100.0 29 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Prolyl oligopeptidase, C-terminal domain
16c3doiA_



100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:esterase;
PDBTitle: crystal structure of a thermostable esterase complex with2 paraoxon
17d2hu7a2



99.9 20 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acylamino-acid-releasing enzyme, C-terminal donain
18d1orva2



99.9 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:DPP6 catalytic domain-like
19d2bgra2



99.9 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:DPP6 catalytic domain-like
20c3k2iA_



99.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 4;
PDBTitle: human acyl-coenzyme a thioesterase 4
21d2jbwa1



not modelled 99.9 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:2,6-dihydropseudooxynicotine hydrolase-like
22c2jbwB_



not modelled 99.9 17 PDB header:hydrolase
Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase;
PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase.
23d1vlqa_



not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetyl xylan esterase-like
24d2b9va2



not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
25c3fnbB_



not modelled 99.9 13 PDB header:hydrolase
Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737;
PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159
26d1xfda2



not modelled 99.8 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:DPP6 catalytic domain-like
27c3hlkB_



not modelled 99.8 13 PDB header:hydrolase
Chain: B: PDB Molecule:acyl-coenzyme a thioesterase 2, mitochondrial;
PDBTitle: crystal structure of human mitochondrial acyl-coa2 thioesterase (acot2)
28d1mpxa2



not modelled 99.8 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
29c2b9vB_



not modelled 99.8 14 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-amino acid ester hydrolase;
PDBTitle: acetobacter turbidans alpha-amino acid ester hydrolase
30d1ju3a2



not modelled 99.8 21 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
31c1l7qA_



not modelled 99.8 21 PDB header:hydrolase
Chain: A: PDB Molecule:cocaine esterase;
PDBTitle: ser117ala mutant of bacterial cocaine esterase coce
32c3ls2D_



not modelled 99.8 14 PDB header:hydrolase
Chain: D: PDB Molecule:s-formylglutathione hydrolase;
PDBTitle: crystal structure of an s-formylglutathione hydrolase from2 pseudoalteromonas haloplanktis tac125
33d1l7aa_



not modelled 99.8 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetyl xylan esterase-like
34c3h2iA_



not modelled 99.8 15 PDB header:hydrolase
Chain: A: PDB Molecule:esterase;
PDBTitle: crystal structure of n228w mutant of the rice cell wall2 degrading esterase lipa from xanthomonas oryzae
35c3bxpA_



not modelled 99.8 9 PDB header:hydrolase
Chain: A: PDB Molecule:putative lipase/esterase;
PDBTitle: crystal structure of a putative carboxylesterase (lp_2923) from2 lactobacillus plantarum wcfs1 at 1.70 a resolution
36c2o2gA_



not modelled 99.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:dienelactone hydrolase;
PDBTitle: crystal structure of dienelactone hydrolase (yp_324580.1) from2 anabaena variabilis atcc 29413 at 1.92 a resolution
37d1lnsa3



not modelled 99.8 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
38c2veoA_



not modelled 99.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:lipase a;
PDBTitle: x-ray structure of candida antarctica lipase a in its2 closed state.
39c3ib3A_



not modelled 99.8 14 PDB header:hydrolase
Chain: A: PDB Molecule:coce/nond family hydrolase;
PDBTitle: crystal structure of sacol2612 - coce/nond family hydrolase from2 staphylococcus aureus
40c3i6yA_



not modelled 99.8 13 PDB header:hydrolase
Chain: A: PDB Molecule:esterase apc40077;
PDBTitle: structure of an esterase from the oil-degrading bacterium oleispira2 antarctica
41c1mpxB_



not modelled 99.8 17 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-amino acid ester hydrolase;
PDBTitle: alpha-amino acid ester hydrolase labeled with selenomethionine
42d1jkma_



not modelled 99.8 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase
43c3fcxA_



not modelled 99.8 15 PDB header:hydrolase
Chain: A: PDB Molecule:s-formylglutathione hydrolase;
PDBTitle: crystal structure of human esterase d
44c3mveB_



not modelled 99.8 11 PDB header:lyase
Chain: B: PDB Molecule:upf0255 protein vv1_0328;
PDBTitle: crystal structure of a novel pyruvate decarboxylase
45c3ksrA_



not modelled 99.8 14 PDB header:hydrolase
Chain: A: PDB Molecule:putative serine hydrolase;
PDBTitle: crystal structure of a putative serine hydrolase (xcc3885) from2 xanthomonas campestris pv. campestris at 2.69 a resolution
46c2zshA_



not modelled 99.7 15 PDB header:hormone receptor
Chain: A: PDB Molecule:probable gibberellin receptor gid1l1;
PDBTitle: structural basis of gibberellin(ga3)-induced della2 recognition by the gibberellin receptor
47c3ed1E_



not modelled 99.7 12 PDB header:hydrolase receptor
Chain: E: PDB Molecule:gibberellin receptor gid1;
PDBTitle: crystal structure of rice gid1 complexed with ga3
48c2o7vA_



not modelled 99.7 17 PDB header:hydrolase
Chain: A: PDB Molecule:cxe carboxylesterase;
PDBTitle: carboxylesterase aecxe1 from actinidia eriantha covalently inhibited2 by paraoxon
49c3f67A_



not modelled 99.7 13 PDB header:hydrolase
Chain: A: PDB Molecule:putative dienelactone hydrolase;
PDBTitle: crystal structure of putative dienelactone hydrolase from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578
50c3fcyB_



not modelled 99.7 15 PDB header:hydrolase
Chain: B: PDB Molecule:xylan esterase 1;
PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485
51d1sfra_



not modelled 99.7 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Mycobacterial antigens
52c2i3dA_



not modelled 99.7 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein atu1826;
PDBTitle: crystal structure of protein of unknown function atu1826, a putative2 alpha/beta hydrolase from agrobacterium tumefaciens
53d2i3da1



not modelled 99.7 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Atu1826-like
54c3e4dD_



not modelled 99.7 14 PDB header:hydrolase
Chain: D: PDB Molecule:esterase d;
PDBTitle: structural and kinetic study of an s-formylglutathione2 hydrolase from agrobacterium tumefaciens
55c3qh4A_



not modelled 99.7 18 PDB header:hydrolase
Chain: A: PDB Molecule:esterase lipw;
PDBTitle: crystal structure of esterase lipw from mycobacterium marinum
56c3d0kA_



not modelled 99.7 13 PDB header:hydrolase
Chain: A: PDB Molecule:putative poly(3-hydroxybutyrate) depolymerase lpqc;
PDBTitle: crystal structure of the lpqc, poly(3-hydroxybutyrate) depolymerase2 from bordetella parapertussis
57c3ga7A_



not modelled 99.7 10 PDB header:hydrolase
Chain: A: PDB Molecule:acetyl esterase;
PDBTitle: 1.55 angstrom crystal structure of an acetyl esterase from salmonella2 typhimurium
58c2wtmC_



not modelled 99.7 18 PDB header:hydrolase
Chain: C: PDB Molecule:est1e;
PDBTitle: est1e from butyrivibrio proteoclasticus
59d1pv1a_



not modelled 99.7 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hypothetical esterase YJL068C
60d1lzla_



not modelled 99.7 20 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase
61d1jjfa_



not modelled 99.7 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase
62d1dina_



not modelled 99.7 20 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Dienelactone hydrolase
63d1f0na_



not modelled 99.7 10 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Mycobacterial antigens
64d1dqza_



not modelled 99.7 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Mycobacterial antigens
65d2fuka1



not modelled 99.7 18 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Atu1826-like
66c1lnsA_



not modelled 99.7 17 PDB header:hydrolase
Chain: A: PDB Molecule:x-prolyl dipeptidyl aminopetidase;
PDBTitle: crystal structure analysis of the x-prolyl dipeptidyl2 aminopeptidase from lactococcus lactis
67d2gzsa1



not modelled 99.7 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:IroE-like
68c3trdA_



not modelled 99.6 15 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase;
PDBTitle: structure of an alpha-beta serine hydrolase homologue from coxiella2 burnetii
69c3hxkB_



not modelled 99.6 16 PDB header:hydrolase
Chain: B: PDB Molecule:sugar hydrolase;
PDBTitle: crystal structure of a sugar hydrolase (yeeb) from2 lactococcus lactis, northeast structural genomics3 consortium target kr108
70c3d7rB_



not modelled 99.6 13 PDB header:hydrolase
Chain: B: PDB Molecule:esterase;
PDBTitle: crystal structure of a putative esterase from staphylococcus aureus
71c3dnmA_



not modelled 99.6 15 PDB header:hydrolase
Chain: A: PDB Molecule:esterase/lipase;
PDBTitle: crystal structure hormone-sensitive lipase from a2 metagenome library
72c2qm0B_



not modelled 99.6 10 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:bes;
PDBTitle: crystal structure of bes protein from bacillus cereus
73c3fakA_



not modelled 99.6 15 PDB header:hydrolase
Chain: A: PDB Molecule:esterase/lipase;
PDBTitle: structural and functional analysis of a hormone-sensitive2 lipase like este5 from a metagenome library
74d2pbla1



not modelled 99.6 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase
75c3bjrA_



not modelled 99.6 11 PDB header:hydrolase
Chain: A: PDB Molecule:putative carboxylesterase;
PDBTitle: crystal structure of a putative carboxylesterase (lp_1002) from2 lactobacillus plantarum wcfs1 at 2.09 a resolution
76c2c7bA_



not modelled 99.6 18 PDB header:hydrolase
Chain: A: PDB Molecule:carboxylesterase;
PDBTitle: the crystal structure of este1, a new thermophilic and2 thermostable carboxylesterase cloned from a metagenomic3 library
77c3llcA_



not modelled 99.6 14 PDB header:hydrolase
Chain: A: PDB Molecule:putative hydrolase;
PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution
78d1jfra_



not modelled 99.6 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Lipase
79c3qm1A_



not modelled 99.6 13 PDB header:hydrolase
Chain: A: PDB Molecule:cinnamoyl esterase;
PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii
80d1vkha_



not modelled 99.6 10 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Putative serine hydrolase Ydr428c
81d1u4na_



not modelled 99.6 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase
82c3h04A_



not modelled 99.6 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50
83d1wb4a1



not modelled 99.6 9 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase
84d1jjia_



not modelled 99.6 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase
85c2wirB_



not modelled 99.6 19 PDB header:hydrolase
Chain: B: PDB Molecule:alpha/beta hydrolase fold-3 domain protein;
PDBTitle: hyperthermophilic esterase from the archeon pyrobaculum2 calidifontis
86c2qruA_



not modelled 99.6 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis
87c3c8dA_



not modelled 99.6 15 PDB header:hydrolase
Chain: A: PDB Molecule:enterochelin esterase;
PDBTitle: crystal structure of the enterobactin esterase fes from2 shigella flexneri in the presence of 2,3-di-hydroxy-n-3 benzoyl-glycine
88c2hdwB_



not modelled 99.5 14 PDB header:hydrolase
Chain: B: PDB Molecule:hypothetical protein pa2218;
PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa
89d1ufoa_



not modelled 99.5 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hypothetical protein TT1662
90c3aikB_



not modelled 99.5 11 PDB header:hydrolase
Chain: B: PDB Molecule:303aa long hypothetical esterase;
PDBTitle: crystal structure of a hsl-like carboxylesterase from sulfolobus2 tokodaii
91c2q0xA_



not modelled 99.5 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: alpha/beta hydrolase fold protein of unknown function
92c2gopB_



not modelled 99.5 15 PDB header:hydrolase
Chain: B: PDB Molecule:trilobed protease;
PDBTitle: the beta-propeller domain of the trilobed protease from pyrococcus2 furiosus reveals an open velcro topology
93d1r88a_



not modelled 99.5 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Mycobacterial antigens
94c2uz0B_



not modelled 99.5 12 PDB header:hydrolase
Chain: B: PDB Molecule:tributyrin esterase;
PDBTitle: the crystal crystal structure of the esta protein, a2 virulence factor esta protein from streptococcus pneumonia
95d1hlga_



not modelled 99.5 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
96c3g8yA_



not modelled 99.5 12 PDB header:hydrolase
Chain: A: PDB Molecule:susd/ragb-associated esterase-like protein;
PDBTitle: crystal structure of a putative hydrolase (bvu_4111) from bacteroides2 vulgatus atcc 8482 at 1.90 a resolution
97c2fx5A_



not modelled 99.5 17 PDB header:hydrolase
Chain: A: PDB Molecule:lipase;
PDBTitle: pseudomonas mendocina lipase
98d3c8da2



not modelled 99.5 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase
99c2h1iA_



not modelled 99.5 12 PDB header:hydrolase
Chain: A: PDB Molecule:carboxylesterase;
PDBTitle: crystal structure of the bacillus cereus carboxylesterase
100d1fj2a_



not modelled 99.5 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase/thioesterase 1
101c1wb4A_



not modelled 99.5 9 PDB header:hydrolase
Chain: A: PDB Molecule:endo-1,4-beta-xylanase y;
PDBTitle: s954a mutant of the feruloyl esterase module from2 clostridium thermocellum complexed with sinapinate
102d2h1ia1



not modelled 99.4 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase/thioesterase 1
103d1k8qa_



not modelled 99.4 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
104c3u0vA_



not modelled 99.4 13 PDB header:hydrolase
Chain: A: PDB Molecule:lysophospholipase-like protein 1;
PDBTitle: crystal structure analysis of human lyplal1
105c3jw8A_



not modelled 99.4 15 PDB header:hydrolase
Chain: A: PDB Molecule:mgll protein;
PDBTitle: crystal structure of human mono-glyceride lipase
106c3nuzF_



not modelled 99.4 12 PDB header:hydrolase
Chain: F: PDB Molecule:putative acetyl xylan esterase;
PDBTitle: crystal structure of a putative acetyl xylan esterase (bf1801) from2 bacteroides fragilis nctc 9343 at 2.30 a resolution
107d3b5ea1



not modelled 99.4 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase/thioesterase 1
108c3hjuB_



not modelled 99.4 15 PDB header:hydrolase
Chain: B: PDB Molecule:monoglyceride lipase;
PDBTitle: crystal structure of human monoglyceride lipase
109c2w8bB_



not modelled 99.4 8 PDB header:protein transport/membrane protein
Chain: B: PDB Molecule:protein tolb;
PDBTitle: crystal structure of processed tolb in complex with pal
110c3og9A_



not modelled 99.4 15 PDB header:hydrolase
Chain: A: PDB Molecule:protein yahd a copper inducible hydrolase;
PDBTitle: structure of yahd with malic acid
111c3dyvA_



not modelled 99.4 13 PDB header:hydrolase
Chain: A: PDB Molecule:esterase d;
PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism
112c3cn9B_



not modelled 99.4 16 PDB header:hydrolase
Chain: B: PDB Molecule:carboxylesterase;
PDBTitle: crystal structure analysis of the carboxylesterase pa3859 from2 pseudomonas aeruginosa pao1- orthorhombic crystal form
113d2bgra1



not modelled 99.3 10 Fold:8-bladed beta-propeller
Superfamily:DPP6 N-terminal domain-like
Family:DPP6 N-terminal domain-like
114c3picB_



not modelled 99.3 16 PDB header:hydrolase
Chain: B: PDB Molecule:cip2;
PDBTitle: glucuronoyl esterase catalytic domain (cip2_ge) from hypocrea jecorina
115d1k32a2



not modelled 99.3 9 Fold:6-bladed beta-propeller
Superfamily:Tricorn protease N-terminal domain
Family:Tricorn protease N-terminal domain
116d1orva1



not modelled 99.3 11 Fold:8-bladed beta-propeller
Superfamily:DPP6 N-terminal domain-like
Family:DPP6 N-terminal domain-like
117d2d81a1



not modelled 99.3 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PHB depolymerase-like
118c3d59B_



not modelled 99.3 21 PDB header:hydrolase
Chain: B: PDB Molecule:platelet-activating factor acetylhydrolase;
PDBTitle: crystal structure of human plasma platelet activating2 factor acetylhydrolase
119c3pe7A_



not modelled 99.3 11 PDB header:lyase
Chain: A: PDB Molecule:oligogalacturonate lyase;
PDBTitle: oligogalacturonate lyase in complex with manganese
120d2b61a1



not modelled 99.3 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0