Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	K	F	D	T	R	T	F	Q	G	L	I	L	T	L	Q	D	Y	W	A	R	Q	G	C	T	I	V	Q	P	L	D	M	E	V	G	A	G	T	S	H	P	M	T	C	L	R	E	L	G	P	E	P	M	A	A	A	Y	V	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																								?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	S	R	R	P	T	D	G	R	Y	G	E	N	P	N	R	L	Q	H	Y	Y	Q	F	Q	V	V	I	K	P	S	P	D	N	I	Q	E	L	Y	L	G	S	L	K	E	L	G	M	D	P	T	I	H	D	I	R	F	V	E	D	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		W	E	N	P	T	L	G	A	W	G	L	G	W	E	V	W	L	N	G	M	E	V	T	Q	F	T	Y	F	Q	Q	V	G	G	L	E	C	K	P	V	T	G	E	I	T	Y	G	L	E	R	L	A	M	Y	I	Q	G	V	D	S	V
Secondary structure
SS confidence
Disorder																																						?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Y	D	L	V	W	S	D	G	P	L	G	K	T	T	Y	G	D	V	F	H	Q	N	E	V	E	Q	S	T	Y	N	F	E	Y	A	D	V	D	F	L	F	T	C	F	E	Q	Y	E	K	E	A	Q	Q	L	L	A	L	E	N	P	L
Secondary structure
SS confidence
Disorder										?	?																																														?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	L	P	A	Y	E	R	I	L	K	A	A	H	S	F	N	L	L	D	A	R	K	A	I	S	V	T	E	R	Q	R	Y	I	L	R	I	R	T	L	T	K	A	V	A	E	A	Y	Y	A	S	R	E	A	L	G	F	P	M	C	N
Secondary structure
SS confidence
Disorder																																																										?	?	?	?
Disorder confidence
		.	.	.
Sequence		K	D	K
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1j5w chain A Region: 9 - 293 Aligned: 274 Modelled: 285 Confidence: 100.0% Identity: 59% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 3rf1 chain B Region: 8 - 294 Aligned: 282 Modelled: 284 Confidence: 100.0% Identity: 65% PDB header:ligase Chain: B: PDB Molecule:glycyl-trna synthetase alpha subunit; PDBTitle: the crystal structure of glycyl-trna synthetase subunit alpha from2 campylobacter jejuni subsp. jejuni nctc 11168 Phyre2 PDB 2zzf chain A Region: 8 - 301 Aligned: 280 Modelled: 294 Confidence: 100.0% Identity: 23% PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of alanyl-trna synthetase without2 oligomerization domain Phyre2 PDB 2ztg chain A Region: 8 - 290 Aligned: 270 Modelled: 279 Confidence: 100.0% Identity: 21% PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus alanyl-trna2 synthetase lacking the c-terminal dimerization domain in3 complex with ala-sa Phyre2 PDB 3hxx chain A Region: 7 - 301 Aligned: 252 Modelled: 260 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of catalytic fragment of e. coli alars in complex2 with amppcp Phyre2 PDB 1yfs chain B Region: 8 - 301 Aligned: 255 Modelled: 270 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: B: PDB Molecule:alanyl-trna synthetase; PDBTitle: the crystal structure of alanyl-trna synthetase in complex2 with l-alanine Phyre2 PDB 1riq chain A domain 2 Region: 8 - 181 Aligned: 171 Modelled: 173 Confidence: 100.0% Identity: 20% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1riq chain A domain 1 Region: 182 - 301 Aligned: 84 Modelled: 100 Confidence: 99.7% Identity: 17% Fold: Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Superfamily: Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Family: Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Phyre2 PDB 1b70 chain A Region: 9 - 198 Aligned: 178 Modelled: 190 Confidence: 97.7% Identity: 19% PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase; PDBTitle: phenylalanyl trna synthetase complexed with phenylalanine Phyre2 PDB 2znj chain B Region: 5 - 180 Aligned: 165 Modelled: 176 Confidence: 97.5% Identity: 18% PDB header:ligase Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of pyrrolysyl-trna synthetase from2 desulfitobacterium hafniense Phyre2 PDB 1jjc chain A Region: 9 - 198 Aligned: 178 Modelled: 190 Confidence: 97.3% Identity: 19% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 3pco chain C Region: 9 - 195 Aligned: 173 Modelled: 186 Confidence: 97.2% Identity: 20% PDB header:ligase Chain: C: PDB Molecule:phenylalanyl-trna synthetase, alpha subunit; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp Phyre2 PDB 2du4 chain B Region: 46 - 238 Aligned: 175 Modelled: 185 Confidence: 97.2% Identity: 17% PDB header:ligase/rna Chain: B: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus o-phosphoseryl-2 trna synthetase complexed with trnacys Phyre2 PDB 1wyd chain B Region: 10 - 192 Aligned: 176 Modelled: 182 Confidence: 97.1% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii Phyre2 PDB 2du7 chain C Region: 35 - 188 Aligned: 145 Modelled: 150 Confidence: 96.9% Identity: 19% PDB header:ligase Chain: C: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of methanococcus jannacshii o-phosphoseryl-trna2 synthetase Phyre2 PDB 1b8a chain A domain 2 Region: 6 - 187 Aligned: 176 Modelled: 182 Confidence: 96.9% Identity: 17% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 3i7f chain A Region: 6 - 192 Aligned: 180 Modelled: 187 Confidence: 96.9% Identity: 19% PDB header:ligase Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: aspartyl trna synthetase from entamoeba histolytica Phyre2 PDB 1asy chain A Region: 6 - 187 Aligned: 174 Modelled: 182 Confidence: 96.7% Identity: 20% PDB header:complex (aminoacyl-trna synthase/trna) Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: class ii aminoacyl transfer rna synthetases: crystal2 structure of yeast aspartyl-trna synthetase complexed with3 trna asp Phyre2 PDB 3l4g chain I Region: 50 - 203 Aligned: 143 Modelled: 154 Confidence: 96.6% Identity: 17% PDB header:ligase Chain: I: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase Phyre2 PDB 1ati chain A domain 2 Region: 53 - 174 Aligned: 121 Modelled: 121 Confidence: 96.4% Identity: 17% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 1 d1j5wa_ 2 c3rf1B_ 3 c2zzfA_ 4 c2ztgA_ 5 c3hxxA_ 6 c1yfsB_ 7 d1riqa2 8 d1riqa1 9 c1b70A_ 10 c2znjB_ 11 d1jjca_ 12 c3pcoC_ 13 c2du4B_ 14 c1wydB_ 15 c2du7C_ 16 d1b8aa2 17 c3i7fA_ 18 c1asyA_ 19 c3l4gI_ 20 d1atia2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1j5wa_ 100.0 59 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 2 c3rf1B_ 100.0 65 PDB header:ligase Chain: B: PDB Molecule:glycyl-trna synthetase alpha subunit; PDBTitle: the crystal structure of glycyl-trna synthetase subunit alpha from2 campylobacter jejuni subsp. jejuni nctc 11168 3 c2zzfA_ 100.0 23 PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of alanyl-trna synthetase without2 oligomerization domain 4 c2ztgA_ 100.0 21 PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus alanyl-trna2 synthetase lacking the c-terminal dimerization domain in3 complex with ala-sa 5 c3hxxA_ 100.0 20 PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of catalytic fragment of e. coli alars in complex2 with amppcp 6 c1yfsB_ 100.0 18 PDB header:ligase Chain: B: PDB Molecule:alanyl-trna synthetase; PDBTitle: the crystal structure of alanyl-trna synthetase in complex2 with l-alanine 7 d1riqa2 100.0 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 8 d1riqa1 99.7 17 Fold:Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Superfamily:Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Family:Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 9 c1b70A_ 97.7 19 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase; PDBTitle: phenylalanyl trna synthetase complexed with phenylalanine 10 c2znjB_ 97.5 18 PDB header:ligase Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of pyrrolysyl-trna synthetase from2 desulfitobacterium hafniense 11 d1jjca_ 97.3 19 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 12 c3pcoC_ 97.2 20 PDB header:ligase Chain: C: PDB Molecule:phenylalanyl-trna synthetase, alpha subunit; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp 13 c2du4B_ 97.2 17 PDB header:ligase/rna Chain: B: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus o-phosphoseryl-2 trna synthetase complexed with trnacys 14 c1wydB_ 97.1 20 PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii 15 c2du7C_ 96.9 19 PDB header:ligase Chain: C: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of methanococcus jannacshii o-phosphoseryl-trna2 synthetase 16 d1b8aa2 96.9 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 17 c3i7fA_ 96.9 19 PDB header:ligase Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: aspartyl trna synthetase from entamoeba histolytica 18 c1asyA_ 96.7 20 PDB header:complex (aminoacyl-trna synthase/trna) Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: class ii aminoacyl transfer rna synthetases: crystal2 structure of yeast aspartyl-trna synthetase complexed with3 trna asp 19 c3l4gI_ 96.6 17 PDB header:ligase Chain: I: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase 20 d1atia2 96.4 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 21 c2zimA_ not modelled 96.2 16 PDB header:ligase Chain: A: PDB Molecule:pyrrolysyl-trna synthetase; PDBTitle: pyrrolysyl-trna synthetase bound to adenylated pyrrolysine and2 pyrophosphate 22 d1b76a2 not modelled 95.9 14 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 23 c2rhqA_ not modelled 95.9 15 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies 24 c2dq3A_ not modelled 95.6 20 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of aq_298 25 c1sryB_ not modelled 94.7 21 PDB header:ligase(synthetase) Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: refined crystal structure of the seryl-trna synthetase from2 thermus thermophilus at 2.5 angstroms resolution 26 d2g4ca2 not modelled 93.9 14 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 27 d1g5ha2 not modelled 93.9 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 28 c3lssA_ not modelled 93.9 20 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp 29 d1n9wa2 not modelled 93.8 26 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 30 d1seta2 not modelled 92.7 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 31 c1wleB_ not modelled 91.1 21 PDB header:ligase Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of mammalian mitochondrial seryl-trna2 synthetase complexed with seryl-adenylate 32 c2dq0A_ not modelled 91.0 21 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of seryl-trna synthetase from pyrococcus2 horikoshii complexed with a seryl-adenylate analog 33 d1h4vb2 not modelled 90.2 21 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 34 c3qo8A_ not modelled 89.1 18 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of seryl-trna synthetase from candida albicans 35 c1e22A_ not modelled 86.8 19 PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase (lysu) hexagonal form complexed with2 lysine and the non-hydrolysable atp analogue amp-pcp 36 d1eova2 not modelled 86.7 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 37 c3bjuB_ not modelled 86.5 23 PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of tetrameric form of human lysyl-trna2 synthetase 38 c1g5hA_ not modelled 86.4 16 PDB header:dna binding protein Chain: A: PDB Molecule:mitochondrial dna polymerase accessory subunit; PDBTitle: crystal structure of the accessory subunit of murine mitochondrial2 polymerase gamma 39 d1c0aa3 not modelled 86.3 30 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 40 c1efwA_ not modelled 85.9 30 PDB header:ligase/rna Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from thermus2 thermophilus complexed to trnaasp from escherichia coli 41 c3e9hB_ not modelled 85.5 32 PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase from bacillus stearothermophilus2 complexed with l-lysylsulfamoyl adenosine 42 c3errB_ not modelled 85.4 17 PDB header:ligase Chain: B: PDB Molecule:fusion protein of microtubule binding domain from PDBTitle: microtubule binding domain from mouse cytoplasmic dynein as2 a fusion with seryl-trna synthetase 43 c2xgtB_ not modelled 85.1 19 PDB header:ligase Chain: B: PDB Molecule:asparaginyl-trna synthetase, cytoplasmic; PDBTitle: asparaginyl-trna synthetase from brugia malayi complexed2 with the sulphamoyl analogue of asparaginyl-adenylate 44 c1n9wA_ not modelled 84.5 28 PDB header:biosynthetic protein Chain: A: PDB Molecule:aspartyl-trna synthetase 2; PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus 45 c1eqrC_ not modelled 84.5 30 PDB header:ligase Chain: C: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of free aspartyl-trna synthetase from2 escherichia coli 46 d1nnha_ not modelled 84.1 21 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 47 d1l0wa3 not modelled 83.3 30 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 48 c3g1zB_ not modelled 83.2 26 PDB header:ligase Chain: B: PDB Molecule:putative lysyl-trna synthetase; PDBTitle: structure of idp01693/yjea, a potential t-rna synthetase from2 salmonella typhimurium 49 c1b8aB_ not modelled 83.2 20 PDB header:ligase Chain: B: PDB Molecule:protein (aspartyl-trna synthetase); PDBTitle: aspartyl-trna synthetase 50 c2cj9A_ not modelled 82.5 15 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of methanosarcina barkeri seryl-trna2 synthetase complexed with an analog of seryladenylate 51 c1x55A_ not modelled 82.4 19 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase; PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue 52 c3m4qA_ not modelled 82.2 25 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase, putative; PDBTitle: entamoeba histolytica asparaginyl-trna synthetase (asnrs) 53 d1qf6a4 not modelled 81.2 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 54 c3mf2B_ not modelled 70.0 15 PDB header:ligase Chain: B: PDB Molecule:bll0957 protein; PDBTitle: crystal structure of class ii aars homologue (bll0957) complexed with2 amp 55 d1e1oa2 not modelled 69.7 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 56 d1kmma2 not modelled 67.0 23 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 57 d1bbua2 not modelled 62.6 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 58 c3nrlB_ not modelled 58.5 22 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein rumgna_01417; PDBTitle: crystal structure of protein rumgna_01417 from ruminococcus gnavus,2 northeast structural genomics consortium target ugr76 59 c1z7nB_ not modelled 52.5 14 PDB header:transferase Chain: B: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: atp phosphoribosyl transferase (hiszg atp-prtase) from2 lactococcus lactis with bound prpp substrate 60 d1wdia_ not modelled 42.8 29 Fold:QueA-like Superfamily:QueA-like Family:QueA-like 61 c3ikmC_ not modelled 41.9 17 PDB header:transferase Chain: C: PDB Molecule:dna polymerase subunit gamma-2; PDBTitle: crystal structure of human mitochondrial dna polymerase2 holoenzyme 62 c3od1A_ not modelled 33.7 16 PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: the crystal structure of an atp phosphoribosyltransferase regulatory2 subunit/histidyl-trna synthetase from bacillus halodurans c 63 d1usya_ not modelled 32.6 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 64 c3racA_ not modelled 30.6 16 PDB header:ligase Chain: A: PDB Molecule:histidine-trna ligase; PDBTitle: crystal strucutre of histidine--trna ligase subunit from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446. 65 d1z7ma1 not modelled 26.2 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 66 d1nj1a3 not modelled 25.5 14 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 67 d1nj8a3 not modelled 23.6 12 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 68 d1wu7a2 not modelled 23.2 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 69 d1gjia1 not modelled 20.8 35 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain 70 c2xczA_ not modelled 20.6 21 PDB header:immune system Chain: A: PDB Molecule:possible atls1-like light-inducible protein; PDBTitle: crystal structure of macrophage migration inhibitory factor2 homologue from prochlorococcus marinus 71 c3cmqA_ not modelled 20.3 16 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase, mitochondrial; PDBTitle: crystal structure of human mitochondrial phenylalanine trna2 synthetase 72 d1eaqa_ not modelled 16.8 31 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:p53-like transcription factors Family:RUNT domain 73 c1gjiA_ not modelled 15.6 33 PDB header:transcription/dna Chain: A: PDB Molecule:c-rel proto-oncogene protein; PDBTitle: crystal structure of c-rel bound to dna 74 d1ljma_ not modelled 15.5 31 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:p53-like transcription factors Family:RUNT domain 75 d1k3zb_ not modelled 13.6 17 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain 76 c3gacD_ not modelled 12.6 15 PDB header:cytokine Chain: D: PDB Molecule:macrophage migration inhibitory factor-like PDBTitle: structure of mif with hpp 77 d1hfoa_ not modelled 11.9 17 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:MIF-related 78 d1my7a_ not modelled 11.2 17 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain 79 d1wh4a_ not modelled 11.1 23 Fold:DEATH domain Superfamily:DEATH domain Family:DEATH domain, DD 80 d1oy3c_ not modelled 10.8 17 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain 81 d1oq1a_ not modelled 10.3 29 Fold:Concanavalin A-like lectins/glucanases Superfamily:Concanavalin A-like lectins/glucanases Family:Hypothetical protein YesU 82 d1dpta_ not modelled 10.0 24 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:MIF-related 83 c3b64A_ not modelled 9.9 11 PDB header:cytokine Chain: A: PDB Molecule:macrophage migration inhibitory factor-like PDBTitle: macrophage migration inhibitory factor (mif) from2 /leishmania major 84 c3t5sA_ not modelled 9.5 16 PDB header:immune system Chain: A: PDB Molecule:macrophage migration inhibitory factor; PDBTitle: structure of macrophage migration inhibitory factor from giardia2 lamblia 85 d2gdga1 not modelled 9.4 17 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:MIF-related 86 d1gd0a_ not modelled 8.8 17 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:MIF-related 87 c2os5C_ not modelled 8.7 15 PDB header:cytokine Chain: C: PDB Molecule:acemif; PDBTitle: macrophage migration inhibitory factor from ancylostoma ceylanicum 88 c3jrtA_ not modelled 7.8 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:integron cassette protein vpc_cass2; PDBTitle: structure from the mobile metagenome of v. paracholerae:2 integron cassette protein vpc_cass2 89 c1zkaA_ not modelled 7.7 13 PDB header:transcription Chain: A: PDB Molecule:transcription factor relb; PDBTitle: nf-kb relb forms an intertwined homodimer, y300s mutant 90 d1vcoa2 not modelled 7.6 29 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 91 d2e1za2 not modelled 7.6 14 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Acetokinase-like 92 c3iacA_ not modelled 7.5 16 PDB header:isomerase Chain: A: PDB Molecule:glucuronate isomerase; PDBTitle: 2.2 angstrom crystal structure of glucuronate isomerase from2 salmonella typhimurium. 93 c3mopM_ not modelled 7.5 15 PDB header:signaling protein, immune system Chain: M: PDB Molecule:interleukin-1 receptor-associated kinase-like 2; PDBTitle: the ternary death domain complex of myd88, irak4, and irak2 94 d1d2zb_ not modelled 7.4 28 Fold:DEATH domain Superfamily:DEATH domain Family:DEATH domain, DD 95 d1uiza_ not modelled 7.0 16 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:MIF-related 96 d1fima_ not modelled 6.8 17 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:MIF-related 97 c1x3nA_ not modelled 6.8 14 PDB header:transferase Chain: A: PDB Molecule:propionate kinase; PDBTitle: crystal structure of amppnp bound propionate kinase (tdcd) from2 salmonella typhimurium 98 d1s1ma2 not modelled 6.8 23 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 99 c1nj8C_ not modelled 6.4 11 PDB header:ligase Chain: C: PDB Molecule:proline-trna synthetase; PDBTitle: crystal structure of prolyl-trna synthetase from2 methanocaldococcus janaschii

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0