Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37769
DateThu Jan 5 11:57:37 GMT 2012
Unique Job ID26bbe21a52ee4f79

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d2ae2a_
Top template information
Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
Confidence and coverage
Confidence:100.0% Coverage: 98%
248 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVEPTETIEQVTALGRRFL
Secondary structure 
SS confidence 
Disorder  ???????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  SLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDALEFSEKDWDDVMNLNIKSV
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  FFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTASKSGVMGVTRLMANEWAKHN
Secondary structure 
SS confidence 
Disorder 
??
?
????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  INVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRWGLPSDLMGPIVFLASSASDYVN
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250...
Sequence  GYTIAVDGGWLAR
Secondary structure 
SS confidence 
Disorder 
?
???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2ae2 chain A

3D model

Region: 5 - 252
Aligned: 248
Modelled: 248
Confidence: 100.0%
Identity: 26%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3cxt chain A

3D model

Region: 1 - 252
Aligned: 245
Modelled: 252
Confidence: 100.0%
Identity: 42%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2

Phyre2

PDB 1gee chain A

3D model

Region: 7 - 252
Aligned: 246
Modelled: 246
Confidence: 100.0%
Identity: 33%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2q2q chain G

3D model

Region: 7 - 253
Aligned: 246
Modelled: 247
Confidence: 100.0%
Identity: 36%
PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida

Phyre2

PDB 2zat chain C

3D model

Region: 7 - 253
Aligned: 247
Modelled: 247
Confidence: 100.0%
Identity: 28%
PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase/reductase sdr family member 4;
PDBTitle: crystal structure of a mammalian reductase

Phyre2

PDB 3svt chain A

3D model

Region: 7 - 253
Aligned: 247
Modelled: 247
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans

Phyre2

PDB 3uf0 chain A

3D model

Region: 5 - 252
Aligned: 246
Modelled: 248
Confidence: 100.0%
Identity: 40%
PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a putative nad(p) dependent gluconate 5-2 dehydrogenase from beutenbergia cavernae(efi target efi-502044) with3 bound nadp (low occupancy)

Phyre2

PDB 1fmc chain A

3D model

Region: 1 - 253
Aligned: 250
Modelled: 253
Confidence: 100.0%
Identity: 28%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1ae1 chain A

3D model

Region: 6 - 252
Aligned: 238
Modelled: 247
Confidence: 100.0%
Identity: 26%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3rih chain B

3D model

Region: 4 - 251
Aligned: 246
Modelled: 248
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase or reductase;
PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus

Phyre2

PDB 1w6u chain A

3D model

Region: 2 - 252
Aligned: 246
Modelled: 251
Confidence: 100.0%
Identity: 28%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1pr9 chain A

3D model

Region: 3 - 252
Aligned: 243
Modelled: 250
Confidence: 100.0%
Identity: 28%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2pd4 chain A domain 1

3D model

Region: 8 - 252
Aligned: 245
Modelled: 245
Confidence: 100.0%
Identity: 16%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1k2w chain A

3D model

Region: 6 - 251
Aligned: 245
Modelled: 246
Confidence: 100.0%
Identity: 31%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3nug chain A

3D model

Region: 7 - 252
Aligned: 244
Modelled: 246
Confidence: 100.0%
Identity: 29%
PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti

Phyre2

PDB 3ak4 chain C

3D model

Region: 5 - 251
Aligned: 246
Modelled: 247
Confidence: 100.0%
Identity: 32%
PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh-dependent quinuclidinone reductase;
PDBTitle: crystal structure of nadh-dependent quinuclidinone reductase from2 agrobacterium tumefaciens

Phyre2

PDB 3icc chain A

3D model

Region: 4 - 251
Aligned: 248
Modelled: 248
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase;
PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution

Phyre2

PDB 2cfc chain B

3D model

Region: 10 - 252
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 28%
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases

Phyre2

PDB 3tox chain G

3D model

Region: 7 - 252
Aligned: 245
Modelled: 246
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021

Phyre2

PDB 3k31 chain B

3D model

Region: 2 - 252
Aligned: 244
Modelled: 251
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution

Phyre2

PDB 3t7c chain C

3D model

Region: 6 - 253
Aligned: 248
Modelled: 248
Confidence: 100.0%
Identity: 33%
PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nad

Phyre2
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d2ae2a_
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c3cxtA_
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d1geea_
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c2q2qG_
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c2zatC_
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c3svtA_
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c3uf0A_
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d1fmca_
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d1ae1a_
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c3rihB_
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d1w6ua_
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d1pr9a_
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d2pd4a1
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d1k2wa_
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c3nugA_
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c3ak4C_
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c3iccA_
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c2cfcB_
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c3toxG_
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c3k31B_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2ae2a_
100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
2c3cxtA_
100.0 42 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2
3d1geea_
100.0 33 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
4c2q2qG_
100.0 36 PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida
5c2zatC_
100.0 28 PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase/reductase sdr family member 4;
PDBTitle: crystal structure of a mammalian reductase
6c3svtA_
100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans
7c3uf0A_
100.0 40 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a putative nad(p) dependent gluconate 5-2 dehydrogenase from beutenbergia cavernae(efi target efi-502044) with3 bound nadp (low occupancy)
8d1fmca_
100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
9d1ae1a_
100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
10c3rihB_
100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase or reductase;
PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus
11d1w6ua_
100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
12d1pr9a_
100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
13d2pd4a1
100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
14d1k2wa_
100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
15c3nugA_
100.0 29 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti
16c3ak4C_
100.0 32 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh-dependent quinuclidinone reductase;
PDBTitle: crystal structure of nadh-dependent quinuclidinone reductase from2 agrobacterium tumefaciens
17c3iccA_
100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase;
PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution
18c2cfcB_
100.0 28 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases
19c3toxG_
100.0 27 PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021
20c3k31B_
100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
21c3lf2B_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain oxidoreductase q9hya2;
PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center
22c3t7cC_
100.0 33 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nad
23c3pk0B_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of short-chain dehydrogenase/reductase sdr from2 mycobacterium smegmatis
24c3gvcB_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable short-chain type
PDBTitle: crystal structure of probable short-chain dehydrogenase-2 reductase from mycobacterium tuberculosis
25d1iy8a_
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
26d1qsga_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
27d1zk4a1
not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
28d1ja9a_
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
29c3gdfA_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable nadp-dependent mannitol dehydrogenase;
PDBTitle: crystal structure of the nadp-dependent mannitol dehydrogenase from2 cladosporium herbarum.
30d1g0oa_
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
31c3gr6A_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of the staphylococcus aureus enoyl-acyl2 carrier protein reductase (fabi) in complex with nadp and3 triclosan
32c1w4zA_
not modelled 100.0 31 PDB header:antibiotic biosynthesis
Chain: A: PDB Molecule:ketoacyl reductase;
PDBTitle: structure of actinorhodin polyketide (actiii) reductase
33d2rhca1
not modelled 100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
34d1hdca_
not modelled 100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
35d1zema1
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
36c2c07A_
not modelled 100.0 35 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: oxoacyl-acp reductase of plasmodium falciparum
37d2c07a1
not modelled 100.0 35 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
38c3grkE_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
39c3itdA_
not modelled 100.0 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:17beta-hydroxysteroid dehydrogenase;
PDBTitle: crystal structure of an inactive 17beta-hydroxysteroid dehydrogenase2 (y167f mutated form) from fungus cochliobolus lunatus
40c3pgxB_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: B: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of a putative carveol dehydrogenase from2 mycobacterium paratuberculosis bound to nicotinamide adenine3 dinucleotide
41c3ijrF_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+
42c3oecA_
not modelled 100.0 38 PDB header:oxidoreductase
Chain: A: PDB Molecule:carveol dehydrogenase (mytha.01326.c, a0r518 homolog);
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium2 thermoresistibile
43c3r3sD_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase;
PDBTitle: structure of the ygha oxidoreductase from salmonella enterica
44c3imfA_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:short chain dehydrogenase;
PDBTitle: 1.99 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor'
45d1vl8a_
not modelled 100.0 36 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
46d1gega_
not modelled 100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
47d1yxma1
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
48d1xhla_
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
49c3v2gA_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of a dehydrogenase/reductase from sinorhizobium2 meliloti 1021
50c2jjyD_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of francisella tularensis enoyl reductase2 (ftfabi) with bound nad
51c3ai3A_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph-sorbose reductase;
PDBTitle: the crystal structure of l-sorbose reductase from gluconobacter2 frateurii complexed with nadph and l-sorbose
52c3afnC_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: C: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of aldose reductase a1-r complexed with nadp
53c2b4qB_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:rhamnolipids biosynthesis 3-oxoacyl-[acyl-
PDBTitle: pseudomonas aeruginosa rhlg/nadp active-site complex
54d1h5qa_
not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
55c3oidA_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadph];
PDBTitle: crystal structure of enoyl-acp reductases iii (fabl) from b. subtilis2 (complex with nadp and tcl)
56d2ew8a1
not modelled 100.0 34 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
57c3ek2D_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b
58d1ulua_
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
59c3sjuA_
not modelled 100.0 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:keto reductase;
PDBTitle: hedamycin polyketide ketoreductase bound to nadph
60c2uvdE_
not modelled 100.0 39 PDB header:oxidoreductase
Chain: E: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: the crystal structure of a 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis (ba3989)
61c3bmrA_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:pteridine reductase;
PDBTitle: structure of pteridine reductase 1 (ptr1) from trypanosoma2 brucei in ternary complex with cofactor (nadp+) and3 inhibitor (compound ax6)
62c3emkA_
not modelled 100.0 36 PDB header:oxidoreductase
Chain: A: PDB Molecule:glucose/ribitol dehydrogenase;
PDBTitle: 2.5a crystal structure of glucose/ribitol dehydrogenase2 from brucella melitensis
63c2pd6D_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8;
PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8
64d1q7ba_
not modelled 100.0 34 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
65d1cyda_
not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
66c3gk3D_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: D: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetoacetyl-coa reductase from2 burkholderia pseudomallei 1710b
67d1nffa_
not modelled 100.0 32 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
68c2qioA_
not modelled 100.0 23 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
69c3uveC_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase ((+)-trans-carveol dehydrogenase);
PDBTitle: crystal structure of carveol dehydrogenase ((+)-trans-carveol2 dehydrogenase) from mycobacterium avium
70c3r1iB_
not modelled 100.0 36 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: crystal structure of a short-chain type dehydrogenase/reductase from2 mycobacterium marinum
71c2et6A_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:(3r)-hydroxyacyl-coa dehydrogenase;
PDBTitle: (3r)-hydroxyacyl-coa dehydrogenase domain of candida tropicalis2 peroxisomal multifunctional enzyme type 2
72d1bdba_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
73d1xkqa_
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
74c2p68A_
not modelled 100.0 33 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5
75c3ftpD_
not modelled 100.0 34 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein)2 reductase from burkholderia pseudomallei at 2.05 a3 resolution
76c2dteB_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:glucose 1-dehydrogenase related protein;
PDBTitle: structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt)2 in complex with nadh
77c3ezlA_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: A: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetyacetyl-coa reductase from2 burkholderia pseudomallei 1710b
78c2wdzD_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: D: PDB Molecule:short-chain dehydrogenase/reductase;
PDBTitle: crystal structure of the short chain dehydrogenase2 galactitol-dehydrogenase (gatdh) of rhodobacter3 sphaeroides in complex with nad+ and 1,2-pentandiol
79d2bgka1
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
80d1x1ta1
not modelled 100.0 41 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
81c3lylB_
not modelled 100.0 35 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis
82c2p91A_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of enoyl-[acyl-carrier-protein] reductase (nadh)2 from aquifex aeolicus vf5
83c3o38D_
not modelled 100.0 33 PDB header:oxidoreductase
Chain: D: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 smegmatis
84c3ctmH_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: H: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of a carbonyl reductase from candida2 parapsilosis with anti-prelog stereo-specificity
85c2z1nA_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure of ape0912 from aeropyrum pernix k1
86d1ydea1
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
87d1hxha_
not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
88d2d1ya1
not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
89c3osuA_
not modelled 100.0 35 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of the 3-oxoacyl-acyl carrier protein reductase,2 fabg, from staphylococcus aureus
90c3sx2F_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative 3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of a putative 3-ketoacyl-(acyl-carrier-protein)2 reductase from mycobacterium paratuberculosis in complex with nad
91c3ppiA_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium
92d1o5ia_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
93d1edoa_
not modelled 100.0 38 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
94d1ulsa_
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
95c3uxyC_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: C: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: the crystal structure of short chain dehydrogenase from rhodobacter2 sphaeroides
96c3rkuC_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: C: PDB Molecule:oxidoreductase ymr226c;
PDBTitle: substrate fingerprint and the structure of nadp+ dependent serine2 dehydrogenase from saccharomyces cerevisiae complexed with nadp+
97c3v2hB_
not modelled 100.0 33 PDB header:oxidoreductase
Chain: B: PDB Molecule:d-beta-hydroxybutyrate dehydrogenase;
PDBTitle: the crystal structure of d-beta-hydroxybutyrate dehydrogenase from2 sinorhizobium meliloti
98d1e6wa_
not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
99c3i4fD_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: structure of putative 3-oxoacyl-reductase from bacillus thuringiensis
100c3sc4A_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:short chain dehydrogenase (a0qtm2 homolog);
PDBTitle: crystal structure of a short chain dehydrogenase (a0qtm2 homolog)2 mycobacterium thermoresistibile
101c3v8bC_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dehydrogenase, possibly 3-oxoacyl-[acyl-carrier
PDBTitle: crystal structure of a 3-ketoacyl-acp reductase from sinorhizobium2 meliloti 1021
102c3llsB_
not modelled 100.0 30 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 mycobacterium tuberculosis
103d2a4ka1
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
104c3pxxE_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: E: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nicotinamide adenine dinucleotide
105c2ph3B_
not modelled 100.0 30 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-[acyl carrier protein] reductase;
PDBTitle: crystal structure of 3-oxoacyl-[acyl carrier protein] reductase2 ttha0415 from thermus thermophilus
106d1mxha_
not modelled 100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
107c2ekqB_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-deoxy-d-gluconate 3-dehydrogenase;
PDBTitle: structure of tt0495 protein from thermus thermophilus
108c3omlA_
not modelled 100.0 30 PDB header:oxidoreductase, hydrolase
Chain: A: PDB Molecule:peroxisomal multifunctional enzyme type 2, cg3415;
PDBTitle: structure of full-length peroxisomal multifunctional enzyme type 22 from drosophila melanogaster
109d1p33a_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
110c3n74A_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 brucella melitensis
111c3f9iB_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase2 rickettsia prowazekii
112c2qhxB_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:pteridine reductase 1;
PDBTitle: structure of pteridine reductase from leishmania major2 complexed with a ligand
113c3un1D_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: D: PDB Molecule:probable oxidoreductase;
PDBTitle: crystal structure of an oxidoreductase from sinorhizobium meliloti2 1021
114c3s55F_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative short-chain dehydrogenase/reductase;
PDBTitle: crystal structure of a putative short-chain dehydrogenase/reductase2 from mycobacterium abscessus bound to nad
115c3diiB_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a carbohydrate specific scor enzyme2 from clostridium thermocellum, ligand-free form
116c3ksuA_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-acyl carrier protein reductase;
PDBTitle: crystal structure of short-chain dehydrogenase from2 oenococcus oeni psu-1
117c3e03C_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: C: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a putative dehydrogenase from2 xanthomonas campestris
118d1spxa_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
119d1uh5a_
not modelled 100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
120d2ag5a1
not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0