Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	K	K	I	H	S	L	A	L	L	V	N	L	G	I	Y	G	V	A	Q	A	Q	E	P	T	D	T	P	V	S	H	D	D	T	I	V	V	T	A	A	E	Q	N	L	Q	A	P	G	V	S	T	I	T	A	D	E	I	R	K
Secondary structure
SS confidence
Disorder		?	?	?	?														?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?									?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		N	P	V	A	R	D	V	S	K	I	I	R	T	M	P	G	V	N	L	T	G	N	S	T	S	G	Q	R	G	N	N	R	Q	I	D	I	R	G	M	G	P	E	N	T	L	I	L	I	D	G	K	P	V	S	S	R	N	S	V	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?											?					?	?	?	?	?	?	?	?	?	?	?	?	?																				?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	G	W	R	G	E	R	D	T	R	G	D	T	S	W	V	P	P	E	M	I	E	R	I	E	V	L	R	G	P	A	A	A	R	Y	G	N	G	A	A	G	G	V	V	N	I	I	T	K	K	G	S	G	E	W	H	G	S	W	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?											?												?	?																			?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	Y	F	N	A	P	E	H	K	E	E	G	A	T	K	R	T	N	F	S	L	T	G	P	L	G	D	E	F	S	F	R	L	Y	G	N	L	D	K	T	Q	A	D	A	W	D	I	N	Q	G	H	Q	S	A	R	A	G	T	Y	A
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?	?	?	?																								?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	T	L	P	A	G	R	E	G	V	I	N	K	D	I	N	G	V	V	R	W	D	F	A	P	L	Q	S	L	E	L	E	A	G	Y	S	R	Q	G	N	L	Y	A	G	D	T	Q	N	T	N	S	D	S	Y	T	R	S	K	Y	G
Secondary structure
SS confidence
Disorder		?	?		?	?	?	?																															?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		D	E	T	N	R	L	Y	R	Q	N	Y	A	L	T	W	N	G	G	W	D	N	G	V	T	T	S	N	W	V	Q	Y	E	H	T	R	N	S	R	I	P	E	G	L	A	G	G	T	E	G	K	F	N	E	K	A	T	Q	D	F	V
Secondary structure
SS confidence
Disorder		?																								?									?	?	?	?	?	?	?	?	?	?		?	?	?	?	?	?	?		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		D	I	D	L	D	D	V	M	L	H	S	E	V	N	L	P	I	D	F	L	V	N	Q	T	L	T	L	G	T	E	W	N	Q	Q	R	M	K	D	L	S	S	N	T	Q	A	L	T	G	T	N	T	G	G	A	I	D	G	V	S	T
Secondary structure
SS confidence
Disorder		?																																					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		T	D	R	S	P	Y	S	K	A	E	I	F	S	L	F	A	E	N	N	M	E	L	T	D	S	T	I	V	T	P	G	L	R	F	D	H	H	S	I	V	G	N	N	W	S	P	A	L	N	I	S	Q	G	L	G	D	D	F	T	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		K	M	G	I	A	R	A	Y	K	A	P	S	L	Y	Q	T	N	P	N	Y	I	L	Y	S	K	G	Q	G	C	Y	A	S	A	G	G	C	Y	L	Q	G	N	D	D	L	K	A	E	T	S	I	N	K	E	I	G	L	E	F	K	R
Secondary structure
SS confidence
Disorder																							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		D	G	W	L	A	G	V	T	W	F	R	N	D	Y	R	N	K	I	E	A	G	Y	V	A	V	G	Q	N	A	V	G	T	D	L	Y	Q	W	D	N	V	P	K	A	V	V	E	G	L	E	G	S	L	N	V	P	V	S	E	T	V
Secondary structure
SS confidence
Disorder																									?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		M	W	T	N	N	I	T	Y	M	L	K	S	E	N	K	T	T	G	D	R	L	S	I	I	P	E	Y	T	L	N	S	T	L	S	W	Q	A	R	E	D	L	S	M	Q	T	T	F	T	W	Y	G	K	Q	Q	P	K	K	Y	N	Y
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?																																					?	?		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence		K	G	Q	P	A	V	G	P	E	T	K	E	I	S	P	Y	S	I	V	G	L	S	A	T	W	D	V	T	K	N	V	S	L	T	G	G	V	D	N	L	F	D	K	R	L	W	R	A	G	N	A	Q	T	T	G	D	L	A	G	A
Secondary structure
SS confidence
Disorder					?	?		?	?	?	?																																									?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.
Sequence		N	Y	I	A	G	A	G	A	Y	T	Y	N	E	P	G	R	T	W	Y	M	S	V	N	T	H	F
Secondary structure
SS confidence
Disorder		?		?	?	?	?	?	?	?																	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1fep chain A Region: 34 - 746 Aligned: 679 Modelled: 679 Confidence: 100.0% Identity: 97% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Ligand-gated protein channel Phyre2 PDB 2iah chain A Region: 22 - 746 Aligned: 671 Modelled: 686 Confidence: 100.0% Identity: 14% PDB header:membrane protein Chain: A: PDB Molecule:ferripyoverdine receptor; PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine. Phyre2 PDB 1xkh chain C Region: 24 - 746 Aligned: 669 Modelled: 686 Confidence: 100.0% Identity: 14% PDB header:membrane protein Chain: C: PDB Molecule:ferripyoverdine receptor; PDBTitle: pyoverdine outer membrane receptor fpva from pseudomonas aeruginosa2 pao1 bound to pyoverdine Phyre2 PDB 3qlb chain A Region: 23 - 746 Aligned: 641 Modelled: 662 Confidence: 100.0% Identity: 15% PDB header:metal transport Chain: A: PDB Molecule:enantio-pyochelin receptor; PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin Phyre2 PDB 1xkw chain A Region: 27 - 746 Aligned: 642 Modelled: 662 Confidence: 100.0% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:fe(iii)-pyochelin receptor; PDBTitle: pyochelin outer membrane receptor fpta from pseudomonas2 aeruginosa Phyre2 PDB 1by5 chain A Region: 23 - 746 Aligned: 674 Modelled: 677 Confidence: 100.0% Identity: 14% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Ligand-gated protein channel Phyre2 PDB 2grx chain B Region: 23 - 746 Aligned: 675 Modelled: 675 Confidence: 100.0% Identity: 12% PDB header:metal transport Chain: B: PDB Molecule:ferrichrome-iron receptor; PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome Phyre2 PDB 3fhh chain A Region: 34 - 746 Aligned: 606 Modelled: 642 Confidence: 100.0% Identity: 18% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane heme receptor shua; PDBTitle: crystal structure of the heme/hemoglobin outer membrane2 transporter shua from shigella dysenteriae Phyre2 PDB 1kmo chain A Region: 35 - 746 Aligned: 645 Modelled: 652 Confidence: 100.0% Identity: 15% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Ligand-gated protein channel Phyre2 PDB 2hdi chain A Region: 34 - 746 Aligned: 577 Modelled: 584 Confidence: 100.0% Identity: 30% PDB header:protein transport,antimicrobial protein Chain: A: PDB Molecule:colicin i receptor; PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia. Phyre2 PDB 1po3 chain A Region: 44 - 746 Aligned: 636 Modelled: 646 Confidence: 100.0% Identity: 15% PDB header:membrane protein Chain: A: PDB Molecule:iron(iii) dicitrate transport protein feca PDBTitle: crystal structure of ferric citrate transporter feca in2 complex with ferric citrate Phyre2 PDB 2guf chain A domain 1 Region: 34 - 746 Aligned: 543 Modelled: 570 Confidence: 100.0% Identity: 24% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Ligand-gated protein channel Phyre2 PDB 3efm chain A Region: 21 - 711 Aligned: 566 Modelled: 586 Confidence: 100.0% Identity: 15% PDB header:membrane protein Chain: A: PDB Molecule:ferric alcaligin siderophore receptor; PDBTitle: structure of the alcaligin outer membrane recepteur faua from2 bordetella pertussis Phyre2 PDB 3csl chain B Region: 41 - 746 Aligned: 674 Modelled: 687 Confidence: 100.0% Identity: 15% PDB header:membrane protein/heme binding protein Chain: B: PDB Molecule:hasr protein; PDBTitle: structure of the serratia marcescens hemophore receptor hasr in2 complex with its hemophore hasa and heme Phyre2 PDB 1t16 chain A Region: 375 - 746 Aligned: 349 Modelled: 357 Confidence: 99.0% Identity: 11% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Outer membrane protein transport protein Phyre2 PDB 3dwo chain X Region: 416 - 688 Aligned: 267 Modelled: 273 Confidence: 97.6% Identity: 13% PDB header:membrane protein Chain: X: PDB Molecule:probable outer membrane protein; PDBTitle: crystal structure of a pseudomonas aeruginosa fadl homologue Phyre2 PDB 3qra chain A Region: 587 - 746 Aligned: 124 Modelled: 132 Confidence: 96.8% Identity: 7% PDB header:cell invasion Chain: A: PDB Molecule:attachment invasion locus protein; PDBTitle: the crystal structure of ail, the attachment invasion locus protein of2 yersinia pestis Phyre2 PDB 3brz chain A Region: 449 - 687 Aligned: 218 Modelled: 239 Confidence: 95.9% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:todx; PDBTitle: crystal structure of the pseudomonas putida toluene2 transporter todx Phyre2 PDB 2k0l chain A Region: 587 - 746 Aligned: 139 Modelled: 140 Confidence: 95.7% Identity: 16% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane protein a; PDBTitle: nmr structure of the transmembrane domain of the outer2 membrane protein a from klebsiella pneumoniae in dhpc3 micelles. Phyre2 PDB 2x27 chain X Region: 586 - 746 Aligned: 153 Modelled: 153 Confidence: 95.5% Identity: 7% PDB header:membrane protein Chain: X: PDB Molecule:outer membrane protein oprg; PDBTitle: crystal structure of the outer membrane protein oprg from2 pseudomonas aeruginosa Phyre2 1 d1fepa_ 2 c2iahA_ 3 c1xkhC_ 4 c3qlbA_ 5 c1xkwA_ 6 d1by5a_ 7 c2grxB_ 8 c3fhhA_ 9 d1kmoa_ 10 c2hdiA_ 11 c1po3A_ 12 d2gufa1 13 c3efmA_ 14 c3cslB_ 15 d1t16a_ 16 c3dwoX_ 17 c3qraA_ 18 c3brzA_ 19 c2k0lA_ 20 c2x27X_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63