Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	V	S	K	K	P	M	V	L	V	I	L	D	G	Y	G	Y	R	E	E	Q	Q	D	N	A	I	F	S	A	K	T	P	V	M	D	A	L	W	A	N	R	P	H	T	L	I	D	A	S	G	L	E	V	G	L	P	D	R	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?															?		?		?																										?			?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	G	N	S	E	V	G	H	V	N	L	G	A	G	R	I	V	Y	Q	D	L	T	R	L	D	V	E	I	K	D	R	A	F	F	A	N	P	V	L	T	G	A	V	D	K	A	K	N	A	G	K	A	V	H	I	M	G	L	L	S
Secondary structure
SS confidence
Disorder			?	?																										?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	G	G	V	H	S	H	E	D	H	I	M	A	M	V	E	L	A	A	E	R	G	A	E	K	I	Y	L	H	A	F	L	D	G	R	D	T	P	P	R	S	A	E	S	S	L	K	K	F	E	E	K	F	A	A	L	G	K	G	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	A	S	I	I	G	R	Y	Y	A	M	D	R	D	N	R	W	D	R	V	E	K	A	Y	D	L	L	T	L	A	Q	G	E	F	Q	A	D	T	A	V	A	G	L	Q	A	A	Y	A	R	D	E	N	D	E	F	V	K	A	T	V
Secondary structure
SS confidence
Disorder																																	?	?																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		I	R	A	E	G	Q	P	D	A	A	M	E	D	G	D	A	L	I	F	M	N	F	R	A	D	R	A	R	E	I	T	R	A	F	V	N	A	D	F	D	G	F	A	R	K	K	V	V	N	V	D	F	V	M	L	T	E	Y	A	A
Secondary structure
SS confidence
Disorder							?																																																					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		D	I	K	T	A	V	A	Y	P	P	A	S	L	V	N	T	F	G	E	W	M	A	K	N	D	K	T	Q	L	R	I	S	E	T	E	K	Y	A	H	V	T	F	F	F	N	G	G	V	E	E	S	F	K	G	E	D	R	I	L	I
Secondary structure
SS confidence
Disorder			?									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		N	S	P	K	V	A	T	Y	D	L	Q	P	E	M	S	S	A	E	L	T	E	K	L	V	A	A	I	K	S	G	K	Y	D	T	I	I	C	N	Y	P	N	G	D	M	V	G	H	T	G	V	M	E	A	A	V	K	A	V	E	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		L	D	H	C	V	E	E	V	A	K	A	V	E	S	V	G	G	Q	L	L	I	T	A	D	H	G	N	A	E	Q	M	R	D	P	A	T	G	Q	A	H	T	A	H	T	N	L	P	V	P	L	I	Y	V	G	D	K	N	V	K	A
Secondary structure
SS confidence
Disorder																																		?	?	?	?	?	?	?																	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.
Sequence		V	E	G	G	K	L	S	D	I	A	P	T	M	L	S	L	M	G	M	E	I	P	Q	E	M	T	G	K	P	L	F	I	V	E
Secondary structure
SS confidence
Disorder		?	?																											?		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1o98 chain A Region: 4 - 512 Aligned: 506 Modelled: 509 Confidence: 100.0% Identity: 50% PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate Phyre2 PDB 3igz chain B Region: 1 - 514 Aligned: 512 Modelled: 514 Confidence: 100.0% Identity: 34% PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration Phyre2 PDB 1o98 chain A domain 1 Region: 79 - 310 Aligned: 231 Modelled: 232 Confidence: 100.0% Identity: 42% Fold: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Superfamily: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Family: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Phyre2 PDB 3idd chain A Region: 6 - 498 Aligned: 348 Modelled: 424 Confidence: 100.0% Identity: 20% PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: cofactor-independent phosphoglycerate mutase from2 thermoplasma acidophilum dsm 1728 Phyre2 PDB 1o98 chain A domain 2 Region: 4 - 512 Aligned: 275 Modelled: 277 Confidence: 100.0% Identity: 60% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain Phyre2 PDB 2zkt chain B Region: 5 - 501 Aligned: 357 Modelled: 373 Confidence: 100.0% Identity: 21% PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii Phyre2 PDB 2i09 chain A Region: 4 - 511 Aligned: 364 Modelled: 384 Confidence: 100.0% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans Phyre2 PDB 3m8y chain C Region: 372 - 511 Aligned: 130 Modelled: 140 Confidence: 99.9% Identity: 25% PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation Phyre2 PDB 2i09 chain A domain 1 Region: 377 - 511 Aligned: 125 Modelled: 135 Confidence: 99.9% Identity: 26% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: DeoB catalytic domain-like Phyre2 PDB 3lxq chain B Region: 316 - 511 Aligned: 185 Modelled: 196 Confidence: 99.8% Identity: 19% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a Phyre2 PDB 1fsu chain A Region: 316 - 511 Aligned: 191 Modelled: 195 Confidence: 99.8% Identity: 13% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 3q3q chain A Region: 388 - 510 Aligned: 123 Modelled: 123 Confidence: 99.8% Identity: 29% PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 Phyre2 PDB 1hdh chain A Region: 316 - 511 Aligned: 192 Modelled: 195 Confidence: 99.8% Identity: 21% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 3b5q chain B Region: 316 - 511 Aligned: 187 Modelled: 196 Confidence: 99.7% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution Phyre2 PDB 1auk chain A Region: 377 - 511 Aligned: 135 Modelled: 135 Confidence: 99.7% Identity: 16% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 2qzu chain A Region: 287 - 511 Aligned: 224 Modelled: 224 Confidence: 99.7% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 Phyre2 PDB 3ed4 chain A Region: 316 - 511 Aligned: 194 Modelled: 196 Confidence: 99.7% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli Phyre2 PDB 1p49 chain A Region: 368 - 511 Aligned: 144 Modelled: 144 Confidence: 99.7% Identity: 19% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 2vqr chain A Region: 374 - 511 Aligned: 137 Modelled: 138 Confidence: 99.7% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily Phyre2 PDB 2w5t chain A Region: 377 - 511 Aligned: 135 Modelled: 135 Confidence: 99.7% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. Phyre2 1 c1o98A_ 2 c3igzB_ 3 d1o98a1 4 c3iddA_ 5 d1o98a2 6 c2zktB_ 7 c2i09A_ 8 c3m8yC_ 9 d2i09a1 10 c3lxqB_ 11 d1fsua_ 12 c3q3qA_ 13 d1hdha_ 14 c3b5qB_ 15 d1auka_ 16 c2qzuA_ 17 c3ed4A_ 18 d1p49a_ 19 c2vqrA_ 20 c2w5tA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1o98A_ 100.0 50 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate 2 c3igzB_ 100.0 34 PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration 3 d1o98a1 100.0 42 Fold:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Superfamily:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain 4 c3iddA_ 100.0 20 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: cofactor-independent phosphoglycerate mutase from2 thermoplasma acidophilum dsm 1728 5 d1o98a2 100.0 60 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain 6 c2zktB_ 100.0 21 PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii 7 c2i09A_ 100.0 18 PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans 8 c3m8yC_ 99.9 25 PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation 9 d2i09a1 99.9 26 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:DeoB catalytic domain-like 10 c3lxqB_ 99.8 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a 11 d1fsua_ 99.8 13 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 12 c3q3qA_ 99.8 29 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 13 d1hdha_ 99.8 21 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 14 c3b5qB_ 99.7 21 PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution 15 d1auka_ 99.7 16 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 16 c2qzuA_ 99.7 13 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 17 c3ed4A_ 99.7 17 PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli 18 d1p49a_ 99.7 19 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 19 c2vqrA_ 99.7 20 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily 20 c2w5tA_ 99.7 14 PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. 21 c2xrgA_ not modelled 99.7 13 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor 22 c2w8dB_ not modelled 99.7 13 PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis 23 c2xr9A_ not modelled 99.7 13 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) 24 d1y6va1 not modelled 99.5 20 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 25 c2iucB_ not modelled 99.4 12 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: structure of alkaline phosphatase from the antarctic2 bacterium tab5 26 c3a52A_ not modelled 99.4 26 PDB header:hydrolase Chain: A: PDB Molecule:cold-active alkaline phosphatase; PDBTitle: crystal structure of cold-active alkailne phosphatase from2 psychrophile shewanella sp. 27 c1ew2A_ not modelled 99.4 17 PDB header:hydrolase Chain: A: PDB Molecule:phosphatase; PDBTitle: crystal structure of a human phosphatase 28 d1k7ha_ not modelled 99.4 21 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 29 d1zeda1 not modelled 99.4 17 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 30 c2gsoB_ not modelled 99.3 25 PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate 31 c2w0yB_ not modelled 99.3 15 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 32 c2x98A_ not modelled 99.3 16 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 33 c3e2dB_ not modelled 99.0 19 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: the 1.4 a crystal structure of the large and cold-active2 vibrio sp. alkaline phosphatase 34 d1ei6a_ not modelled 98.2 16 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Phosphonoacetate hydrolase 35 c3szzA_ not modelled 97.7 24 PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate 36 c2d1gB_ not modelled 97.4 9 PDB header:hydrolase Chain: B: PDB Molecule:acid phosphatase; PDBTitle: structure of francisella tularensis acid phosphatase a (acpa) bound to2 orthovanadate 37 c3m0zD_ not modelled 91.9 15 PDB header:lyase Chain: D: PDB Molecule:putative aldolase; PDBTitle: crystal structure of putative aldolase from klebsiella2 pneumoniae. 38 c3m6yA_ not modelled 79.6 18 PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase; PDBTitle: structure of 4-hydroxy-2-oxoglutarate aldolase from bacillus cereus at2 1.45 a resolution. 39 c3muxB_ not modelled 75.3 18 PDB header:lyase Chain: B: PDB Molecule:putative 4-hydroxy-2-oxoglutarate aldolase; PDBTitle: the crystal structure of a putative 4-hydroxy-2-oxoglutarate aldolase2 from bacillus anthracis to 1.45a 40 c1qzwC_ not modelled 47.3 18 PDB header:signaling protein/rna Chain: C: PDB Molecule:signal recognition 54 kda protein; PDBTitle: crystal structure of the complete core of archaeal srp and2 implications for inter-domain communication 41 d1vyva2 not modelled 46.8 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 42 c3ib7A_ not modelled 46.1 16 PDB header:hydrolase Chain: A: PDB Molecule:icc protein; PDBTitle: crystal structure of full length rv0805 43 c3tovB_ not modelled 44.0 29 PDB header:transferase Chain: B: PDB Molecule:glycosyl transferase family 9; PDBTitle: the crystal structure of the glycosyl transferase family 9 from2 veillonella parvula dsm 2008 44 c2j37W_ not modelled 43.9 17 PDB header:ribosome Chain: W: PDB Molecule:signal recognition particle 54 kda protein PDBTitle: model of mammalian srp bound to 80s rncs 45 c2iy3A_ not modelled 28.9 15 PDB header:rna-binding Chain: A: PDB Molecule:signal recognition particle protein ffh; PDBTitle: structure of the e. coli signal recognition particle2 bound to a translating ribosome 46 d2nxfa1 not modelled 27.8 16 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:ADPRibase-Mn-like 47 d1vyua2 not modelled 26.9 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 48 d2z3va1 not modelled 24.3 22 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 49 d1iq0a1 not modelled 24.0 33 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 50 d1whua_ not modelled 23.8 55 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Family:Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 51 d1o57a1 not modelled 23.8 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:N-terminal domain of Bacillus PurR 52 d1f7ua1 not modelled 23.3 17 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 53 d1ydga_ not modelled 22.7 9 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:WrbA-like 54 c2ip1A_ not modelled 22.1 16 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure analysis of s. cerevisiae tryptophanyl trna2 synthetase 55 c2j289_ not modelled 21.2 15 PDB header:ribosome Chain: 9: PDB Molecule:signal recognition particle 54; PDBTitle: model of e. coli srp bound to 70s rncs 56 c3dm5A_ not modelled 20.0 17 PDB header:rna binding protein, transport protein Chain: A: PDB Molecule:signal recognition 54 kda protein; PDBTitle: structures of srp54 and srp19, the two proteins assembling2 the ribonucleic core of the signal recognition particle3 from the archaeon pyrococcus furiosus. 57 d1pkxa1 not modelled 19.9 17 Fold:Methylglyoxal synthase-like Superfamily:Methylglyoxal synthase-like Family:Inosicase 58 c4a1oB_ not modelled 18.6 12 PDB header:transferase-hydrolase Chain: B: PDB Molecule:bifunctional purine biosynthesis protein purh; PDBTitle: crystal structure of mycobacterium tuberculosis purh complexed with2 aicar and a novel nucleotide cfair, at 2.48 a resolution. 59 d2a9pa1 not modelled 17.6 14 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 60 c3m6mF_ not modelled 17.5 26 PDB header:lyase/transferase Chain: F: PDB Molecule:sensory/regulatory protein rpfc; PDBTitle: crystal structure of rpff complexed with rec domain of rpfc 61 d1s8na_ not modelled 15.3 17 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 62 d1ys7a2 not modelled 14.9 11 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 63 c3cwoX_ not modelled 14.4 25 PDB header:de novo protein Chain: X: PDB Molecule:beta/alpha-barrel protein based on 1thf and 1tmy; PDBTitle: a beta/alpha-barrel built by the combination of fragments2 from different folds 64 c3oaaO_ not modelled 14.0 21 PDB header:hydrolase/transport protein Chain: O: PDB Molecule:atp synthase gamma chain; PDBTitle: structure of the e.coli f1-atp synthase inhibited by subunit epsilon 65 d1u0sy_ not modelled 14.0 22 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 66 c2nwqA_ not modelled 14.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:probable short-chain dehydrogenase; PDBTitle: short chain dehydrogenase from pseudomonas aeruginosa 67 d1g8fa3 not modelled 13.6 23 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ATP sulfurylase C-terminal domain 68 c2vy9A_ not modelled 13.2 16 PDB header:gene regulation Chain: A: PDB Molecule:anti-sigma-factor antagonist; PDBTitle: molecular architecture of the stressosome, a signal2 integration and transduction hub 69 c3qg5D_ not modelled 13.2 15 PDB header:hydrolase Chain: D: PDB Molecule:mre11; PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair 70 c3dzdA_ not modelled 13.2 14 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of sigma54 activator ntrc4 in the inactive2 state 71 d2enda_ not modelled 12.6 63 Fold:T4 endonuclease V Superfamily:T4 endonuclease V Family:T4 endonuclease V 72 d1q74a_ not modelled 12.6 16 Fold:LmbE-like Superfamily:LmbE-like Family:LmbE-like 73 d2f99a1 not modelled 12.6 16 Fold:Cystatin-like Superfamily:NTF2-like Family:SnoaL-like polyketide cyclase 74 c2qy9A_ not modelled 11.8 13 PDB header:protein transport Chain: A: PDB Molecule:cell division protein ftsy; PDBTitle: structure of the ng+1 construct of the e. coli srp receptor2 ftsy 75 d2b7oa1 not modelled 11.8 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class-II DAHP synthetase 76 d1c8ba_ not modelled 11.7 24 Fold:Phosphorylase/hydrolase-like Superfamily:HybD-like Family:Germination protease 77 c3hv0A_ not modelled 11.6 10 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from cryptosporidium parvum 78 c2q8uA_ not modelled 11.3 13 PDB header:hydrolase Chain: A: PDB Molecule:exonuclease, putative; PDBTitle: crystal structure of mre11 from thermotoga maritima msb8 (tm1635) at2 2.20 a resolution 79 c3lcmB_ not modelled 10.6 13 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of smu.1420 from streptococcus mutans ua159 80 c1iq0A_ not modelled 10.3 35 PDB header:ligase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: thermus thermophilus arginyl-trna synthetase 81 c2j48A_ not modelled 10.1 11 PDB header:transferase Chain: A: PDB Molecule:two-component sensor kinase; PDBTitle: nmr structure of the pseudo-receiver domain of the cika2 protein. 82 c3t8yA_ not modelled 10.0 19 PDB header:hydrolase Chain: A: PDB Molecule:chemotaxis response regulator protein-glutamate PDBTitle: crystal structure of the response regulator domain of thermotoga2 maritima cheb 83 c2gwrA_ not modelled 9.9 12 PDB header:signaling protein Chain: A: PDB Molecule:dna-binding response regulator mtra; PDBTitle: crystal structure of the response regulator protein mtra from2 mycobacterium tuberculosis 84 c2g2qB_ not modelled 9.7 27 PDB header:oxidoreductase Chain: B: PDB Molecule:glutaredoxin-2; PDBTitle: the crystal structure of g4, the poxviral disulfide oxidoreductase2 essential for cytoplasmic disulfide bond formation 85 c3grcD_ not modelled 9.5 10 PDB header:transferase Chain: D: PDB Molecule:sensor protein, kinase; PDBTitle: crystal structure of a sensor protein from polaromonas sp.2 js666 86 c2xmoB_ not modelled 9.3 23 PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 87 c2og2A_ not modelled 9.3 16 PDB header:protein transport Chain: A: PDB Molecule:putative signal recognition particle receptor; PDBTitle: crystal structure of chloroplast ftsy from arabidopsis2 thaliana 88 c2zwmA_ not modelled 9.1 15 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein yycf; PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis 89 d1fs0g_ not modelled 8.9 15 Fold:Pyruvate kinase C-terminal domain-like Superfamily:ATP synthase (F1-ATPase), gamma subunit Family:ATP synthase (F1-ATPase), gamma subunit 90 c3a0rB_ not modelled 8.9 26 PDB header:transferase Chain: B: PDB Molecule:response regulator; PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360) 91 d1lpbb2 not modelled 8.8 44 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 92 d2qwxa1 not modelled 8.8 11 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Quinone reductase 93 d1mb3a_ not modelled 8.7 15 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 94 c3cu5B_ not modelled 8.7 7 PDB header:transcription regulator Chain: B: PDB Molecule:two component transcriptional regulator, arac family; PDBTitle: crystal structure of a two component transcriptional regulator arac2 from clostridium phytofermentans isdg 95 c3bh1A_ not modelled 8.6 26 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0371 protein dip2346; PDBTitle: crystal structure of protein dip2346 from corynebacterium diphtheriae 96 c2qv0A_ not modelled 8.6 15 PDB header:transcription Chain: A: PDB Molecule:protein mrke; PDBTitle: crystal structure of the response regulatory domain of2 protein mrke from klebsiella pneumoniae 97 d1dz3a_ not modelled 8.4 7 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 98 d1hska2 not modelled 8.4 23 Fold:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain Superfamily:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain Family:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 99 c2xokG_ not modelled 8.4 33 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: refined structure of yeast f1c10 atpase complex to 3 a2 resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0