Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	S	A	L	K	K	S	V	V	S	T	S	I	S	L	I	L	A	S	G	M	A	A	F	A	A	H	A	A	D	D	V	K	L	K	A	T	K	T	N	V	A	F	S	D	F	T	P	T	E	Y	S	T	K	G	K	P	N	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?																																			?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	V	L	T	M	D	D	L	G	Y	G	Q	L	P	F	D	K	G	S	F	D	P	K	T	M	E	N	R	E	V	V	D	T	Y	K	I	G	I	D	K	A	I	E	A	A	Q	K	S	T	P	T	L	L	S	L	M	D	E	G	V
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	F	T	N	G	Y	V	A	H	G	V	S	G	P	S	R	A	A	I	M	T	G	R	A	P	A	R	F	G	V	Y	S	N	T	D	A	Q	D	G	I	P	L	T	E	T	F	L	P	E	L	F	Q	N	H	G	Y	Y	T	A	A
Secondary structure
SS confidence
Disorder																																				?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	G	K	W	H	L	S	K	I	S	N	V	P	V	P	E	D	K	Q	T	R	D	Y	H	D	N	F	T	T	F	S	A	E	E	W	Q	P	Q	N	R	G	F	D	Y	F	M	G	F	H	A	A	G	T	A	Y	Y	N	S	P	S
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?																			?		?																	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	F	K	N	R	E	R	V	P	A	K	G	Y	I	S	D	Q	L	T	D	E	A	I	G	V	V	D	R	A	K	T	L	D	Q	P	F	M	L	Y	L	A	Y	N	A	P	H	L	P	N	D	N	P	A	P	D	Q	Y	Q	K	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		F	N	T	G	S	Q	T	A	D	N	Y	Y	A	S	V	Y	S	V	D	Q	G	V	K	R	I	L	E	Q	L	K	K	N	G	Q	Y	D	N	T	I	I	L	F	T	S	D	N	G	A	V	I	D	G	P	L	P	L	N	G	A	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?																																									?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		K	G	Y	K	S	Q	T	Y	P	G	G	T	H	T	P	M	F	M	W	W	K	G	K	L	Q	P	G	N	Y	D	K	L	I	S	A	M	D	F	Y	P	T	A	L	D	A	A	D	I	S	I	P	K	D	L	K	L	D	G	V	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		L	L	P	W	L	Q	D	K	K	Q	G	E	P	H	K	N	L	T	W	I	T	S	Y	S	H	W	F	D	E	E	N	I	P	F	W	D	N	Y	H	K	F	V	R	H	Q	S	D	D	Y	P	H	N	P	N	T	E	D	L	S	Q
Secondary structure
SS confidence
Disorder									?	?	?		?	?										?	?	?	?		?	?	?	?								?	?	?		?	?	?	?	?	?	?						?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		F	S	Y	T	V	R	N	N	D	Y	S	L	V	Y	T	V	E	N	N	Q	L	G	L	Y	K	L	T	D	L	Q	Q	K	D	N	L	A	A	A	N	P	Q	V	V	K	E	M	Q	G	V	V	R	E	F	I	D	S	S	Q	P	P
Secondary structure
SS confidence
Disorder																																		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence		L	S	E	V	N	Q	E	K	F	N	N	I	K	K	A	L	S	E	A	K
Secondary structure
SS confidence
Disorder																			?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3ed4 chain A Region: 57 - 540 Aligned: 422 Modelled: 427 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli Phyre2 PDB 1hdh chain A Region: 56 - 538 Aligned: 392 Modelled: 396 Confidence: 100.0% Identity: 29% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 2qzu chain A Region: 50 - 544 Aligned: 426 Modelled: 429 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 Phyre2 PDB 1fsu chain A Region: 55 - 550 Aligned: 418 Modelled: 423 Confidence: 100.0% Identity: 27% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 1p49 chain A Region: 54 - 545 Aligned: 429 Modelled: 449 Confidence: 100.0% Identity: 30% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 1auk chain A Region: 56 - 544 Aligned: 420 Modelled: 430 Confidence: 100.0% Identity: 26% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 2vqr chain A Region: 57 - 540 Aligned: 431 Modelled: 445 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily Phyre2 PDB 3b5q chain B Region: 56 - 547 Aligned: 389 Modelled: 395 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution Phyre2 PDB 3lxq chain B Region: 33 - 538 Aligned: 380 Modelled: 401 Confidence: 100.0% Identity: 18% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a Phyre2 PDB 2w8d chain B Region: 54 - 547 Aligned: 379 Modelled: 384 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis Phyre2 PDB 2w5t chain A Region: 54 - 532 Aligned: 365 Modelled: 372 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. Phyre2 PDB 2zkt chain B Region: 57 - 409 Aligned: 269 Modelled: 273 Confidence: 100.0% Identity: 19% PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii Phyre2 PDB 3m8y chain C Region: 56 - 425 Aligned: 314 Modelled: 327 Confidence: 100.0% Identity: 16% PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation Phyre2 PDB 3q3q chain A Region: 50 - 430 Aligned: 337 Modelled: 338 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 Phyre2 PDB 2gso chain B Region: 56 - 426 Aligned: 275 Modelled: 292 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate Phyre2 PDB 2i09 chain A Region: 55 - 426 Aligned: 312 Modelled: 331 Confidence: 100.0% Identity: 15% PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans Phyre2 PDB 1o98 chain A domain 2 Region: 56 - 422 Aligned: 274 Modelled: 293 Confidence: 100.0% Identity: 18% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain Phyre2 PDB 3szz chain A Region: 53 - 403 Aligned: 291 Modelled: 291 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate Phyre2 PDB 2i09 chain A domain 1 Region: 59 - 426 Aligned: 246 Modelled: 273 Confidence: 100.0% Identity: 20% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: DeoB catalytic domain-like Phyre2 PDB 1ei6 chain A Region: 52 - 403 Aligned: 296 Modelled: 305 Confidence: 100.0% Identity: 16% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Phosphonoacetate hydrolase Phyre2 1 c3ed4A_ 2 d1hdha_ 3 c2qzuA_ 4 d1fsua_ 5 d1p49a_ 6 d1auka_ 7 c2vqrA_ 8 c3b5qB_ 9 c3lxqB_ 10 c2w8dB_ 11 c2w5tA_ 12 c2zktB_ 13 c3m8yC_ 14 c3q3qA_ 15 c2gsoB_ 16 c2i09A_ 17 d1o98a2 18 c3szzA_ 19 d2i09a1 20 d1ei6a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3ed4A_ 100.0 27 PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli 2 d1hdha_ 100.0 29 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 3 c2qzuA_ 100.0 23 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 4 d1fsua_ 100.0 27 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 5 d1p49a_ 100.0 30 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 6 d1auka_ 100.0 26 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 7 c2vqrA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily 8 c3b5qB_ 100.0 24 PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution 9 c3lxqB_ 100.0 18 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a 10 c2w8dB_ 100.0 19 PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis 11 c2w5tA_ 100.0 19 PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. 12 c2zktB_ 100.0 19 PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii 13 c3m8yC_ 100.0 16 PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation 14 c3q3qA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 15 c2gsoB_ 100.0 24 PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate 16 c2i09A_ 100.0 15 PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans 17 d1o98a2 100.0 18 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain 18 c3szzA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate 19 d2i09a1 100.0 20 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:DeoB catalytic domain-like 20 d1ei6a_ 100.0 16 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Phosphonoacetate hydrolase 21 c2xrgA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor 22 c2xr9A_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) 23 c2d1gB_ not modelled 99.9 11 PDB header:hydrolase Chain: B: PDB Molecule:acid phosphatase; PDBTitle: structure of francisella tularensis acid phosphatase a (acpa) bound to2 orthovanadate 24 c1o98A_ not modelled 99.9 22 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate 25 c3igzB_ not modelled 99.8 14 PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration 26 d1y6va1 not modelled 99.6 19 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 27 c2iucB_ not modelled 99.6 14 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: structure of alkaline phosphatase from the antarctic2 bacterium tab5 28 c2w0yB_ not modelled 99.5 14 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 29 c2x98A_ not modelled 99.5 16 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 30 c1ew2A_ not modelled 99.5 17 PDB header:hydrolase Chain: A: PDB Molecule:phosphatase; PDBTitle: crystal structure of a human phosphatase 31 d1k7ha_ not modelled 99.5 17 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 32 d1zeda1 not modelled 99.5 17 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 33 c3a52A_ not modelled 99.4 14 PDB header:hydrolase Chain: A: PDB Molecule:cold-active alkaline phosphatase; PDBTitle: crystal structure of cold-active alkailne phosphatase from2 psychrophile shewanella sp. 34 c3e2dB_ not modelled 99.3 16 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: the 1.4 a crystal structure of the large and cold-active2 vibrio sp. alkaline phosphatase 35 c3iddA_ not modelled 95.8 30 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: cofactor-independent phosphoglycerate mutase from2 thermoplasma acidophilum dsm 1728 36 d1b4ub_ not modelled 59.3 24 Fold:Phosphorylase/hydrolase-like Superfamily:LigB-like Family:LigB-like 37 d3cu0a1 not modelled 40.3 35 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:1,3-glucuronyltransferase 38 d2iw0a1 not modelled 33.7 34 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:NodB-like polysaccharide deacetylase 39 c2d0jD_ not modelled 33.4 24 PDB header:transferase Chain: D: PDB Molecule:galactosylgalactosylxylosylprotein 3-beta- PDBTitle: crystal structure of human glcat-s apo form 40 c2r1fB_ not modelled 32.7 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:predicted aminodeoxychorismate lyase; PDBTitle: crystal structure of predicted aminodeoxychorismate lyase from2 escherichia coli 41 d1v82a_ not modelled 30.8 34 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:1,3-glucuronyltransferase 42 c3oaaO_ not modelled 25.4 6 PDB header:hydrolase/transport protein Chain: O: PDB Molecule:atp synthase gamma chain; PDBTitle: structure of the e.coli f1-atp synthase inhibited by subunit epsilon 43 d1xo1a2 not modelled 24.2 15 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 44 c2iw0A_ not modelled 24.2 36 PDB header:hydrolase Chain: A: PDB Molecule:chitin deacetylase; PDBTitle: structure of the chitin deacetylase from the fungal2 pathogen colletotrichum lindemuthianum 45 d1h7na_ not modelled 21.1 20 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 46 d1j33a_ not modelled 18.6 11 Fold:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 47 d1mm0a_ not modelled 18.0 6 Fold:Knottins (small inhibitors, toxins, lectins) Superfamily:Scorpion toxin-like Family:Insect defensins 48 d1okga1 not modelled 17.9 15 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 49 d1dc1a_ not modelled 17.9 16 Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Restriction endonuclease BsobI 50 d1l5oa_ not modelled 16.9 20 Fold:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 51 d1skyb3 not modelled 16.5 33 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 52 d1tfra2 not modelled 15.2 19 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 53 d1fx0a3 not modelled 14.4 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 54 c3oaaC_ not modelled 14.1 19 PDB header:hydrolase/transport protein Chain: C: PDB Molecule:atp synthase subunit alpha; PDBTitle: structure of the e.coli f1-atp synthase inhibited by subunit epsilon 55 d1uzdc1 not modelled 13.9 19 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 56 c2vyoA_ not modelled 11.7 19 PDB header:hydrolase Chain: A: PDB Molecule:chitooligosaccharide deacetylase; PDBTitle: chitin deacetylase family member from encephalitozoon2 cuniculi 57 d1v7ba2 not modelled 11.7 21 Fold:Tetracyclin repressor-like, C-terminal domain Superfamily:Tetracyclin repressor-like, C-terminal domain Family:Tetracyclin repressor-like, C-terminal domain 58 c3k6sB_ not modelled 11.6 18 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-2; PDBTitle: structure of integrin alphaxbeta2 ectodomain 59 d2cz4a1 not modelled 11.6 19 Fold:Ferredoxin-like Superfamily:GlnB-like Family:Prokaryotic signal transducing protein 60 d1l6sa_ not modelled 11.5 33 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 61 d1skye3 not modelled 11.1 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 62 c3k1tA_ not modelled 10.9 17 PDB header:ligase Chain: A: PDB Molecule:glutamate--cysteine ligase gsha; PDBTitle: crystal structure of putative gamma-glutamylcysteine synthetase2 (yp_546622.1) from methylobacillus flagellatus kt at 1.90 a3 resolution 63 d1ej7s_ not modelled 10.4 21 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 64 c1kmhA_ not modelled 10.3 15 PDB header:hydrolase Chain: A: PDB Molecule:atpase alpha subunit; PDBTitle: crystal structure of spinach chloroplast f1-atpase2 complexed with tentoxin 65 c3nrxB_ not modelled 10.2 11 PDB header:protein binding Chain: B: PDB Molecule:protein regulator of cytokinesis 1; PDBTitle: insights into anti-parallel microtubule crosslinking by prc1, a2 conserved non-motor microtubule binding protein 66 c2w6jG_ not modelled 10.1 25 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: low resolution structures of bovine mitochondrial f1-atpase2 during controlled dehydration: hydration state 5. 67 d2b8ea1 not modelled 9.8 32 Fold:HAD-like Superfamily:HAD-like Family:Meta-cation ATPase, catalytic domain P 68 c2wl8D_ not modelled 9.0 24 PDB header:protein transport Chain: D: PDB Molecule:peroxisomal biogenesis factor 19; PDBTitle: x-ray crystal structure of pex19p 69 d1gzga_ not modelled 8.9 26 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 70 c1w0jB_ not modelled 8.7 15 PDB header:hydrolase Chain: B: PDB Molecule:atp synthase alpha chain heart isoform, PDBTitle: beryllium fluoride inhibited bovine f1-atpase 71 d2c1ha1 not modelled 8.7 26 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 72 c2ihnA_ not modelled 8.7 16 PDB header:hydrolase/dna Chain: A: PDB Molecule:ribonuclease h; PDBTitle: co-crystal of bacteriophage t4 rnase h with a fork dna2 substrate 73 c3tixB_ not modelled 8.6 50 PDB header:gene regulation/protein binding Chain: B: PDB Molecule:chromo domain-containing protein 1; PDBTitle: crystal structure of the chp1-tas3 complex core 74 c1okgA_ not modelled 8.4 14 PDB header:transferase Chain: A: PDB Molecule:possible 3-mercaptopyruvate sulfurtransferase; PDBTitle: 3-mercaptopyruvate sulfurtransferase from leishmania major 75 c2qe7G_ not modelled 8.1 44 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma; PDBTitle: crystal structure of the f1-atpase from the thermoalkaliphilic2 bacterium bacillus sp. ta2.a1 76 c2c61A_ not modelled 8.0 7 PDB header:hydrolase Chain: A: PDB Molecule:a-type atp synthase non-catalytic subunit b; PDBTitle: crystal structure of the non-catalytic b subunit of a-type2 atpase from m. mazei go1 77 c2pw0A_ not modelled 7.8 15 PDB header:unknown function Chain: A: PDB Molecule:prpf methylaconitate isomerase; PDBTitle: crystal structure of trans-aconitate bound to methylaconitate2 isomerase prpf from shewanella oneidensis 78 d2jdig1 not modelled 7.7 38 Fold:Pyruvate kinase C-terminal domain-like Superfamily:ATP synthase (F1-ATPase), gamma subunit Family:ATP synthase (F1-ATPase), gamma subunit 79 c3olhA_ not modelled 7.6 12 PDB header:transferase Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase; PDBTitle: human 3-mercaptopyruvate sulfurtransferase 80 d8ruci_ not modelled 7.6 19 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 81 c3obkH_ not modelled 7.3 41 PDB header:lyase Chain: H: PDB Molecule:delta-aminolevulinic acid dehydratase; PDBTitle: crystal structure of delta-aminolevulinic acid dehydratase2 (porphobilinogen synthase) from toxoplasma gondii me49 in complex3 with the reaction product porphobilinogen 82 c2qe7C_ not modelled 7.2 26 PDB header:hydrolase Chain: C: PDB Molecule:atp synthase subunit alpha; PDBTitle: crystal structure of the f1-atpase from the thermoalkaliphilic2 bacterium bacillus sp. ta2.a1 83 c2r9vA_ not modelled 7.1 22 PDB header:hydrolase Chain: A: PDB Molecule:atp synthase subunit alpha; PDBTitle: crystal structure of atp synthase subunit alpha (tm1612) from2 thermotoga maritima at 2.10 a resolution 84 c2xokG_ not modelled 7.0 26 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: refined structure of yeast f1c10 atpase complex to 3 a2 resolution 85 c2fa5B_ not modelled 6.9 25 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator marr/emrr family; PDBTitle: the crystal structure of an unliganded multiple antibiotic-2 resistance repressor (marr) from xanthomonas campestris 86 c2w6fA_ not modelled 6.6 15 PDB header:hydrolase Chain: A: PDB Molecule:atp synthase subunit alpha heart isoform, PDBTitle: low resolution structures of bovine mitochondrial f1-atpase2 during controlled dehydration: hydration state 2. 87 c2go4A_ not modelled 6.5 24 PDB header:hydrolase Chain: A: PDB Molecule:udp-3-o-[3-hydroxymyristoyl] n-acetylglucosamine PDBTitle: crystal structure of aquifex aeolicus lpxc complexed with tu-514 88 c1u8cB_ not modelled 6.5 23 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; PDBTitle: a novel adaptation of the integrin psi domain revealed from its2 crystal structure 89 c3p3vB_ not modelled 6.5 38 PDB header:transferase Chain: B: PDB Molecule:pts system, n-acetylgalactosamine-specific iib component; PDBTitle: crystal structure of a pts dependent n-acetyl-galactosamine-iib2 component (agav, spy_0631) from streptococcus pyogenes at 1.65 a3 resolution 90 d1szpb1 not modelled 6.5 14 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 91 c3ov5A_ not modelled 5.9 13 PDB header:protein transport Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: atomic structure of the xanthomonas citri virb7 globular domain. 92 c3iydC_ not modelled 5.9 16 PDB header:transcription/dna Chain: C: PDB Molecule:dna-directed rna polymerase subunit beta; PDBTitle: three-dimensional em structure of an intact activator-dependent2 transcription initiation complex 93 c2eceA_ not modelled 5.8 4 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:462aa long hypothetical selenium-binding protein; PDBTitle: x-ray structure of hypothetical selenium-binding protein2 from sulfolobus tokodaii, st0059 94 d2jdia3 not modelled 5.5 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 95 c2vocA_ not modelled 5.5 29 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: thioredoxin a active site mutants form mixed disulfide2 dimers that resemble enzyme-substrate reaction3 intermediate 96 c3ippA_ not modelled 5.4 16 PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase ynje; PDBTitle: crystal structure of sulfur-free ynje 97 d1qopb_ not modelled 5.4 11 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 98 d1g8fa3 not modelled 5.3 22 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ATP sulfurylase C-terminal domain 99 d1tg7a2 not modelled 5.2 25 Fold:Galactose-binding domain-like Superfamily:Galactose-binding domain-like Family:Beta-galactosidase LacA, domains 4 and 5

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0