Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	N	S	R	L	F	R	L	S	R	I	V	I	A	L	T	A	A	S	G	M	M	V	N	T	A	N	A	K	E	E	A	K	A	A	T	Q	Y	T	Q	Q	V	N	Q	N	Y	A	K	S	L	P	F	S	D	R	Q	D	F	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?												?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?																			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	A	Q	R	G	F	I	A	P	L	L	D	E	G	I	L	R	D	A	N	G	K	V	Y	Y	R	A	D	D	Y	K	F	D	I	N	A	A	A	P	E	T	V	N	P	S	L	W	R	Q	S	Q	I	N	G	I	S	G	L	F	K
Secondary structure
SS confidence
Disorder																																?	?	?	?		?	?	?	?	?	?										?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	T	D	K	M	Y	Q	V	R	G	Q	D	I	S	N	I	T	F	V	E	G	E	K	G	I	I	V	I	D	P	L	V	T	P	P	A	A	K	A	A	L	D	L	Y	F	Q	H	R	P	Q	K	P	I	V	A	V	I	Y	T	H
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	H	T	D	H	Y	G	G	V	K	G	I	I	S	E	A	D	V	K	S	G	K	V	Q	V	I	A	P	A	G	F	M	D	E	A	I	S	E	N	V	L	A	G	N	I	M	S	R	R	A	L	Y	S	Y	G	L	L	L	P	H
Secondary structure
SS confidence
Disorder																																										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		N	A	Q	G	N	V	G	N	G	L	G	V	T	L	A	T	G	D	P	S	I	I	A	P	T	K	T	I	V	R	T	G	E	K	M	I	I	D	G	L	E	F	D	F	L	M	T	P	G	S	E	A	P	A	E	M	H	F	Y	I
Secondary structure
SS confidence
Disorder													?	?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		P	A	L	K	A	L	C	T	A	E	N	A	T	H	T	L	H	N	F	Y	T	L	R	G	A	K	T	R	D	T	S	K	W	T	E	Y	L	N	E	T	L	D	M	W	G	N	D	A	E	V	L	F	M	P	H	T	W	P	V	W
Secondary structure
SS confidence
Disorder																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	N	K	H	I	N	D	Y	I	G	K	Y	R	D	T	I	K	Y	I	H	D	Q	T	L	H	L	A	N	Q	G	Y	T	M	N	E	I	G	D	M	I	K	L	P	P	A	L	A	N	N	W	A	S	R	G	Y	Y	G	S	V	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		H	N	A	R	A	V	Y	N	F	Y	L	G	Y	Y	D	G	N	P	A	N	L	H	P	Y	G	Q	V	E	M	G	K	R	Y	V	Q	A	L	G	G	S	A	R	V	I	N	L	A	Q	E	A	N	K	Q	G	D	Y	R	W	S	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		E	L	L	K	Q	V	I	A	A	N	P	G	D	Q	V	A	K	N	L	Q	A	N	N	F	E	Q	L	G	Y	Q	A	E	S	A	T	W	R	G	F	Y	L	T	G	A	K	E	L	R	E	G	V	H	K	F	S	H	G	T	T	G
Secondary structure
SS confidence
Disorder																																																	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		S	P	D	T	I	R	G	M	S	V	E	M	L	F	D	F	M	A	V	R	L	D	S	A	K	A	A	G	K	N	I	S	L	N	F	N	M	S	N	G	D	N	L	N	L	T	L	N	D	S	V	L	N	Y	R	K	T	L	Q	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		Q	A	D	A	S	F	Y	I	S	R	E	D	L	H	A	V	L	T	G	Q	A	K	M	A	D	L	V	K	A	K	K	A	K	I	I	G	N	G	A	K	L	E	E	I	I	A	C	L	D	N	F	D	L	W	V	N	I	V	T	P
Secondary structure
SS confidence
Disorder																				?			?							?	?	?																												?	?
Disorder confidence
		.
Sequence		N
Secondary structure
SS confidence
Disorder		?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2cfu chain A Region: 30 - 660 Aligned: 623 Modelled: 631 Confidence: 100.0% Identity: 45% PDB header:hydrolase Chain: A: PDB Molecule:sdsa1; PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid. Phyre2 PDB 2cfu chain A domain 2 Region: 30 - 533 Aligned: 500 Modelled: 504 Confidence: 100.0% Identity: 47% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Alkylsulfatase-like Phyre2 PDB 2q0i chain A domain 1 Region: 119 - 431 Aligned: 277 Modelled: 294 Confidence: 100.0% Identity: 17% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: PqsE-like Phyre2 PDB 3spu chain B Region: 102 - 377 Aligned: 225 Modelled: 237 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase ndm-1; PDBTitle: apo ndm-1 crystal structure Phyre2 PDB 2zo4 chain A Region: 121 - 400 Aligned: 257 Modelled: 280 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:metallo-beta-lactamase family protein; PDBTitle: crystal structure of metallo-beta-lactamase family protein ttha14292 from thermus thermophilus hb8 Phyre2 PDB 1ych chain D Region: 119 - 510 Aligned: 335 Modelled: 352 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: D: PDB Molecule:nitric oxide reductase; PDBTitle: x-ray crystal structures of moorella thermoacetica fpra.2 novel diiron site structure and mechanistic insights into3 a scavenging nitric oxide reductase Phyre2 PDB 2ohi chain B Region: 114 - 507 Aligned: 341 Modelled: 355 Confidence: 100.0% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:type a flavoprotein fpra; PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state Phyre2 PDB 1jjt chain A Region: 118 - 376 Aligned: 200 Modelled: 218 Confidence: 100.0% Identity: 16% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 PDB 1m2x chain A Region: 118 - 377 Aligned: 206 Modelled: 218 Confidence: 100.0% Identity: 15% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 PDB 1ko3 chain A Region: 118 - 376 Aligned: 207 Modelled: 221 Confidence: 100.0% Identity: 17% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 PDB 3sd9 chain B Region: 118 - 375 Aligned: 222 Modelled: 235 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of serratia fonticola sfh-i: source of the2 nucleophile in the catalytic mechanism of mono-zinc metallo-beta-3 lactamases Phyre2 PDB 1e5d chain A Region: 120 - 481 Aligned: 313 Modelled: 322 Confidence: 100.0% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:rubredoxin\:oxygen oxidoreductase; PDBTitle: rubredoxin oxygen:oxidoreductase (roo) from anaerobe2 desulfovibrio gigas Phyre2 PDB 1x8h chain A Region: 118 - 377 Aligned: 220 Modelled: 237 Confidence: 100.0% Identity: 22% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 PDB 2q9u chain B Region: 120 - 378 Aligned: 210 Modelled: 219 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:a-type flavoprotein; PDBTitle: crystal structure of the flavodiiron protein from giardia2 intestinalis Phyre2 PDB 2fhx chain B Region: 118 - 377 Aligned: 228 Modelled: 244 Confidence: 100.0% Identity: 16% PDB header:hydrolase, metal binding protein Chain: B: PDB Molecule:spm-1; PDBTitle: pseudomonas aeruginosa spm-1 metallo-beta-lactamase Phyre2 PDB 1e5d chain A domain 2 Region: 120 - 377 Aligned: 211 Modelled: 214 Confidence: 100.0% Identity: 18% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: ROO N-terminal domain-like Phyre2 PDB 3rkj chain A Region: 118 - 379 Aligned: 211 Modelled: 227 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase ndm-1; PDBTitle: crystal structure of new delhi metallo-beta-lactamase-1 from2 klebsiella pnueumoniae Phyre2 PDB 1znb chain A Region: 118 - 379 Aligned: 208 Modelled: 220 Confidence: 100.0% Identity: 16% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 PDB 1vme chain B Region: 118 - 450 Aligned: 280 Modelled: 287 Confidence: 100.0% Identity: 20% PDB header:electron transport Chain: B: PDB Molecule:flavoprotein; PDBTitle: crystal structure of flavoprotein (tm0755) from thermotoga maritima at2 1.80 a resolution Phyre2 PDB 1mqo chain A Region: 118 - 370 Aligned: 199 Modelled: 211 Confidence: 100.0% Identity: 14% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 1 c2cfuA_ 2 d2cfua2 3 d2q0ia1 4 c3spuB_ 5 c2zo4A_ 6 c1ychD_ 7 c2ohiB_ 8 d1jjta_ 9 d1m2xa_ 10 d1ko3a_ 11 c3sd9B_ 12 c1e5dA_ 13 d1x8ha_ 14 c2q9uB_ 15 c2fhxB_ 16 d1e5da2 17 c3rkjA_ 18 d1znba_ 19 c1vmeB_ 20 d1mqoa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235