Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	Q	I	A	R	S	V	A	L	A	F	N	N	L	P	R	P	H	R	V	M	L	G	S	L	T	V	L	T	L	A	V	A	V	W	R	P	Y	V	Y	H	R	D	A	T	P	I	V	K	T	I	E	L	E	Q	N	E	I	R
Secondary structure
SS confidence
Disorder		?	?																																		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	L	L	P	E	A	S	E	P	I	D	Q	A	A	Q	E	D	E	A	I	P	Q	D	E	L	D	D	K	I	A	G	E	A	G	V	H	E	Y	V	V	S	T	G	D	T	L	S	S	I	L	N	Q	Y	G	I	D	M	G	D	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	Q	L	A	A	A	D	K	E	L	R	N	L	K	I	G	Q	Q	L	S	W	T	L	T	A	D	G	E	L	Q	R	L	T	W	E	V	S	R	R	E	T	R	T	Y	D	R	T	A	A	N	G	F	K	M	T	S	E	M	Q	Q
Secondary structure
SS confidence
Disorder							?			?			?																											?													?					?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	E	W	V	N	N	L	L	K	G	T	V	G	G	S	F	V	A	S	A	R	N	A	G	L	T	S	A	E	V	S	A	V	I	K	A	M	Q	W	Q	M	D	F	R	K	L	K	K	G	D	E	F	A	V	L	M	S	R	E	M
Secondary structure
SS confidence
Disorder		?	?	?																				?		?																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	D	G	K	R	E	Q	S	Q	L	L	G	V	R	L	R	S	E	G	K	D	Y	Y	A	I	R	A	E	D	G	K	F	Y	D	R	N	G	T	G	L	A	K	G	F	L	R	F	P	T	A	K	Q	F	R	I	S	S	N	F	N
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																						?	?	?	?	?	?	?	?			?	?	?								?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		P	R	R	T	N	P	V	T	G	R	V	A	P	H	R	G	V	D	F	A	M	P	Q	G	T	P	V	L	S	V	G	D	G	E	V	V	V	A	K	R	S	G	A	A	G	Y	Y	V	A	I	R	H	G	R	S	Y	T	T	R	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		M	H	L	R	K	I	L	V	K	P	G	Q	K	V	K	R	G	D	R	I	A	L	S	G	N	T	G	R	S	T	G	P	H	L	H	Y	E	V	W	I	N	Q	Q	A	V	N	P	L	T	A	K	L	P	R	T	E	G	L	T	G
Secondary structure
SS confidence
Disorder										?	?	?																																								?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440
Sequence		S	D	R	R	E	F	L	A	Q	A	K	E	I	V	P	Q	L	R	F	D
Secondary structure
SS confidence
Disorder																		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2gu1 chain A Region: 96 - 413 Aligned: 318 Modelled: 318 Confidence: 100.0% Identity: 42% PDB header:hydrolase Chain: A: PDB Molecule:zinc peptidase; PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae Phyre2 PDB 2hsi chain B Region: 272 - 414 Aligned: 128 Modelled: 143 Confidence: 100.0% Identity: 37% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative peptidase m23; PDBTitle: crystal structure of putative peptidase m23 from2 pseudomonas aeruginosa, new york structural genomics3 consortium Phyre2 PDB 3nyy chain A Region: 208 - 411 Aligned: 203 Modelled: 204 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:putative glycyl-glycine endopeptidase lytm; PDBTitle: crystal structure of a putative glycyl-glycine endopeptidase lytm2 (rumgna_02482) from ruminococcus gnavus atcc 29149 at 1.60 a3 resolution Phyre2 PDB 1qwy chain A Region: 271 - 411 Aligned: 138 Modelled: 141 Confidence: 100.0% Identity: 33% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Peptidoglycan hydrolase LytM Phyre2 PDB 2b44 chain A Region: 285 - 411 Aligned: 119 Modelled: 127 Confidence: 100.0% Identity: 38% PDB header:hydrolase Chain: A: PDB Molecule:glycyl-glycine endopeptidase lytm; PDBTitle: truncated s. aureus lytm, p 32 2 1 crystal form Phyre2 PDB 3it5 chain B Region: 279 - 410 Aligned: 128 Modelled: 132 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:protease lasa; PDBTitle: crystal structure of the lasa virulence factor from pseudomonas2 aeruginosa Phyre2 PDB 3csq chain C Region: 286 - 409 Aligned: 112 Modelled: 119 Confidence: 99.9% Identity: 23% PDB header:hydrolase Chain: C: PDB Molecule:morphogenesis protein 1; PDBTitle: crystal and cryoem structural studies of a cell wall2 degrading enzyme in the bacteriophage phi29 tail Phyre2 PDB 2f3g chain A Region: 304 - 383 Aligned: 75 Modelled: 80 Confidence: 97.1% Identity: 20% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 1gla chain F Region: 304 - 383 Aligned: 75 Modelled: 80 Confidence: 97.0% Identity: 19% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 2gpr chain A Region: 304 - 383 Aligned: 75 Modelled: 80 Confidence: 96.7% Identity: 17% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 1gpr chain A Region: 304 - 383 Aligned: 75 Modelled: 80 Confidence: 96.7% Identity: 15% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 2auk chain A Region: 319 - 382 Aligned: 64 Modelled: 64 Confidence: 95.8% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of e. coli rna polymerase beta' g/g' insert Phyre2 PDB 1brw chain A domain 3 Region: 321 - 383 Aligned: 55 Modelled: 63 Confidence: 93.8% Identity: 24% Fold: alpha/beta-Hammerhead Superfamily: Pyrimidine nucleoside phosphorylase C-terminal domain Family: Pyrimidine nucleoside phosphorylase C-terminal domain Phyre2 PDB 1dcz chain A Region: 320 - 384 Aligned: 65 Modelled: 65 Confidence: 93.3% Identity: 20% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1ci3 chain M domain 2 Region: 329 - 380 Aligned: 51 Modelled: 52 Confidence: 93.3% Identity: 18% Fold: Barrel-sandwich hybrid Superfamily: Rudiment single hybrid motif Family: Cytochrome f, small domain Phyre2 PDB 1e2w chain A domain 2 Region: 329 - 380 Aligned: 52 Modelled: 52 Confidence: 93.2% Identity: 19% Fold: Barrel-sandwich hybrid Superfamily: Rudiment single hybrid motif Family: Cytochrome f, small domain Phyre2 PDB 2tpt chain A domain 3 Region: 321 - 383 Aligned: 55 Modelled: 63 Confidence: 92.5% Identity: 20% Fold: alpha/beta-Hammerhead Superfamily: Pyrimidine nucleoside phosphorylase C-terminal domain Family: Pyrimidine nucleoside phosphorylase C-terminal domain Phyre2 PDB 2kcc chain A Region: 325 - 395 Aligned: 71 Modelled: 71 Confidence: 92.2% Identity: 21% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 Phyre2 PDB 2ejg chain D Region: 327 - 384 Aligned: 58 Modelled: 58 Confidence: 91.9% Identity: 21% PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 Phyre2 PDB 1otp chain A Region: 321 - 383 Aligned: 55 Modelled: 63 Confidence: 91.6% Identity: 20% PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase Phyre2 1 c2gu1A_ 2 c2hsiB_ 3 c3nyyA_ 4 d1qwya_ 5 c2b44A_ 6 c3it5B_ 7 c3csqC_ 8 d2f3ga_ 9 d1glaf_ 10 d2gpra_ 11 d1gpra_ 12 c2aukA_ 13 d1brwa3 14 d1dcza_ 15 d1ci3m2 16 d1e2wa2 17 d2tpta3 18 c2kccA_ 19 c2ejgD_ 20 c1otpA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2gu1A_ 100.0 42 PDB header:hydrolase Chain: A: PDB Molecule:zinc peptidase; PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae 2 c2hsiB_ 100.0 37 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative peptidase m23; PDBTitle: crystal structure of putative peptidase m23 from2 pseudomonas aeruginosa, new york structural genomics3 consortium 3 c3nyyA_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:putative glycyl-glycine endopeptidase lytm; PDBTitle: crystal structure of a putative glycyl-glycine endopeptidase lytm2 (rumgna_02482) from ruminococcus gnavus atcc 29149 at 1.60 a3 resolution 4 d1qwya_ 100.0 33 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Peptidoglycan hydrolase LytM 5 c2b44A_ 100.0 38 PDB header:hydrolase Chain: A: PDB Molecule:glycyl-glycine endopeptidase lytm; PDBTitle: truncated s. aureus lytm, p 32 2 1 crystal form 6 c3it5B_ 100.0 21 PDB header:hydrolase Chain: B: PDB Molecule:protease lasa; PDBTitle: crystal structure of the lasa virulence factor from pseudomonas2 aeruginosa 7 c3csqC_ 99.9 23 PDB header:hydrolase Chain: C: PDB Molecule:morphogenesis protein 1; PDBTitle: crystal and cryoem structural studies of a cell wall2 degrading enzyme in the bacteriophage phi29 tail 8 d2f3ga_ 97.1 20 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 9 d1glaf_ 97.0 19 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 10 d2gpra_ 96.7 17 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 11 d1gpra_ 96.7 15 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 12 c2aukA_ 95.8 16 PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of e. coli rna polymerase beta' g/g' insert 13 d1brwa3 93.8 24 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 14 d1dcza_ 93.3 20 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 15 d1ci3m2 93.3 18 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 16 d1e2wa2 93.2 19 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 17 d2tpta3 92.5 20 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 18 c2kccA_ 92.2 21 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 19 c2ejgD_ 91.9 21 PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 20 c1otpA_ 91.6 20 PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase 21 c2j0fC_ not modelled 91.6 25 PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design 22 c1e2vB_ not modelled 91.4 17 PDB header:electron transport proteins Chain: B: PDB Molecule:cytochrome f; PDBTitle: n153q mutant of cytochrome f from chlamydomonas reinhardtii 23 c1ctmA_ not modelled 91.1 17 PDB header:electron transport(cytochrome) Chain: A: PDB Molecule:cytochrome f; PDBTitle: crystal structure of chloroplast cytochrome f reveals a2 novel cytochrome fold and unexpected heme ligation 24 c1q90A_ not modelled 90.7 17 PDB header:photosynthesis Chain: A: PDB Molecule:apocytochrome f; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii 25 c3h5qA_ not modelled 90.6 20 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase; PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus 26 c2jxmB_ not modelled 90.2 16 PDB header:electron transport Chain: B: PDB Molecule:cytochrome f; PDBTitle: ensemble of twenty structures of the prochlorothrix2 hollandica plastocyanin- cytochrome f complex 27 d1bdoa_ not modelled 90.0 18 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 28 c2b8gA_ not modelled 90.0 17 PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) 29 d1uoua3 not modelled 89.9 22 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 30 c3n6rK_ not modelled 89.5 25 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 31 c2dsjA_ not modelled 88.2 37 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase; PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8 32 c1tu2B_ not modelled 87.2 16 PDB header:electron transport Chain: B: PDB Molecule:apocytochrome f; PDBTitle: the complex of nostoc cytochrome f and plastocyanin determin with2 paramagnetic nmr. based on the structures of cytochrome f and3 plastocyanin, 10 structures 33 d1ghja_ not modelled 87.2 19 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 34 c3lnnB_ not modelled 87.1 22 PDB header:metal transport Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux PDBTitle: crystal structure of zneb from cupriavidus metallidurans 35 c1t5eB_ not modelled 86.8 30 PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa 36 c2k33A_ not modelled 86.2 30 PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation 37 c2f1mA_ not modelled 86.1 17 PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra 38 c1brwB_ not modelled 85.7 22 PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation 39 d1o78a_ not modelled 85.2 39 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 40 c3fppB_ not modelled 84.7 26 PDB header:membrane protein Chain: B: PDB Molecule:macrolide-specific efflux protein maca; PDBTitle: crystal structure of e.coli maca 41 d1vf7a_ not modelled 84.7 27 Fold:HlyD-like secretion proteins Superfamily:HlyD-like secretion proteins Family:HlyD-like secretion proteins 42 d1iyua_ not modelled 84.2 24 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 43 c2aujD_ not modelled 83.4 20 PDB header:transferase Chain: D: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of thermus aquaticus rna polymerase beta'-subunit2 insert 44 d1qjoa_ not modelled 83.4 24 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 45 c2ejmA_ not modelled 82.5 13 PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase 46 c3camB_ not modelled 82.4 23 PDB header:gene regulation Chain: B: PDB Molecule:cold-shock domain family protein; PDBTitle: crystal structure of the cold shock domain protein from neisseria2 meningitidis 47 c2q8iB_ not modelled 81.0 26 PDB header:transferase Chain: B: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase component of PDBTitle: pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug2 radicicol 48 d1tu2b2 not modelled 80.8 23 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 49 c2qf7A_ not modelled 80.3 21 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase protein; PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli 50 c2dn8A_ not modelled 80.1 22 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase 51 c2l5tA_ not modelled 79.6 17 PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase; PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum 52 d1y8ob1 not modelled 79.2 26 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 53 d1laba_ not modelled 78.5 17 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 54 d1gjxa_ not modelled 77.8 16 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 55 c2e75C_ not modelled 75.6 17 PDB header:photosynthesis Chain: C: PDB Molecule:apocytochrome f; PDBTitle: crystal structure of the cytochrome b6f complex with 2-nonyl-4-2 hydroxyquinoline n-oxide (nqno) from m.laminosus 56 d1k8ma_ not modelled 75.3 13 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 57 c3fmcC_ not modelled 75.3 20 PDB header:hydrolase Chain: C: PDB Molecule:putative succinylglutamate desuccinylase / aspartoacylase; PDBTitle: crystal structure of a putative succinylglutamate desuccinylase /2 aspartoacylase family protein (sama_0604) from shewanella amazonensis3 sb2b at 1.80 a resolution 58 d2pnrc1 not modelled 74.7 26 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 59 c2qj8B_ not modelled 74.2 8 PDB header:hydrolase Chain: B: PDB Molecule:mlr6093 protein; PDBTitle: crystal structure of an aspartoacylase family protein (mlr6093) from2 mesorhizobium loti maff303099 at 2.00 a resolution 60 c2dneA_ not modelled 73.8 30 PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: solution structure of rsgi ruh-058, a lipoyl domain of2 human 2-oxoacid dehydrogenase 61 c2dncA_ not modelled 73.4 30 PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase protein x component; PDBTitle: solution structure of rsgi ruh-054, a lipoyl domain from2 human 2-oxoacid dehydrogenase 62 c3h9iB_ not modelled 72.5 22 PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli 63 d1h95a_ not modelled 72.5 20 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 64 c3aqqD_ not modelled 71.9 20 PDB header:dna binding protein Chain: D: PDB Molecule:calcium-regulated heat stable protein 1; PDBTitle: crystal structure of human crhsp-24 65 c2vbcA_ not modelled 69.2 19 PDB header:hydrolase Chain: A: PDB Molecule:dengue 4 ns3 full-length protein; PDBTitle: crystal structure of the ns3 protease-helicase from dengue2 virus 66 c3a0jB_ not modelled 68.6 18 PDB header:transcription Chain: B: PDB Molecule:cold shock protein; PDBTitle: crystal structure of cold shock protein 1 from thermus2 thermophilus hb8 67 c2jkuA_ not modelled 67.0 37 PDB header:ligase Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain, PDBTitle: crystal structure of the n-terminal region of the biotin2 acceptor domain of human propionyl-coa carboxylase 68 d2es2a1 not modelled 66.9 14 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 69 d1pmra_ not modelled 66.3 22 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 70 c3na6A_ not modelled 62.2 27 PDB header:hydrolase Chain: A: PDB Molecule:succinylglutamate desuccinylase/aspartoacylase; PDBTitle: crystal structure of a succinylglutamate desuccinylase (tm1040_2694)2 from silicibacter sp. tm1040 at 2.00 a resolution 71 d1mjca_ not modelled 59.9 16 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 72 d1c9oa_ not modelled 58.8 18 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 73 c2ytyA_ not modelled 57.7 24 PDB header:rna binding protein Chain: A: PDB Molecule:cold shock domain-containing protein e1; PDBTitle: solution structure of the fourth cold-shock domain of the human2 kiaa0885 protein (unr protein) 74 c3cdxB_ not modelled 56.7 15 PDB header:hydrolase Chain: B: PDB Molecule:succinylglutamatedesuccinylase/aspartoacylase; PDBTitle: crystal structure of2 succinylglutamatedesuccinylase/aspartoacylase from3 rhodobacter sphaeroides 75 d1g6pa_ not modelled 56.4 18 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 76 c2bh8B_ not modelled 56.2 18 PDB header:transcription Chain: B: PDB Molecule:1b11; PDBTitle: combinatorial protein 1b11 77 c3ozxA_ not modelled 56.1 15 PDB header:hydrolase, translation Chain: A: PDB Molecule:rnase l inhibitor; PDBTitle: crystal structure of abce1 of sulfolubus solfataricus (-fes domain) 78 c2k5nA_ not modelled 56.1 26 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative cold-shock protein; PDBTitle: solution nmr structure of the n-terminal domain of protein2 eca1580 from erwinia carotovora, northeast structural3 genomics consortium target ewr156a 79 c2q6oB_ not modelled 54.7 31 PDB header:biosynthetic protein Chain: B: PDB Molecule:hypothetical protein; PDBTitle: sall-y70t with sam and cl 80 c2zbvC_ not modelled 54.6 22 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized conserved protein; PDBTitle: crystal structure of uncharacterized conserved protein from thermotoga2 maritima 81 d1o4ua2 not modelled 53.7 21 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 82 c2xoaA_ not modelled 52.8 34 PDB header:metal transport Chain: A: PDB Molecule:ryanodine receptor 1; PDBTitle: crystal structure of the n-terminal three domains of the2 skeletal muscle ryanodine receptor (ryr1) 83 c1rqrA_ not modelled 51.8 16 PDB header:transferase Chain: A: PDB Molecule:5'-fluoro-5'-deoxyadenosine synthase; PDBTitle: crystal structure and mechanism of a bacterial fluorinating enzyme,2 product complex 84 c1xjvA_ not modelled 51.1 12 PDB header:transcription/dna Chain: A: PDB Molecule:protection of telomeres 1; PDBTitle: crystal structure of human pot1 bound to telomeric single-2 stranded dna (ttagggttag) 85 d1qapa2 not modelled 48.3 11 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 86 c3ilaG_ not modelled 48.0 34 PDB header:signaling protein Chain: G: PDB Molecule:ryanodine receptor 1; PDBTitle: crystal structure of rabbit ryanodine receptor 1 n-terminal domain (9-2 205) 87 c3n9tA_ not modelled 46.4 15 PDB header:oxidoreductase Chain: A: PDB Molecule:pnpc; PDBTitle: cryatal structure of hydroxyquinol 1,2-dioxygenase from pseudomonas2 putida dll-e4 88 c3trzE_ not modelled 46.0 14 PDB header:rna binding protein/rna Chain: E: PDB Molecule:protein lin-28 homolog a; PDBTitle: mouse lin28a in complex with let-7d microrna pre-element 89 d1e0ga_ not modelled 45.9 31 Fold:LysM domain Superfamily:LysM domain Family:LysM domain 90 c2l9yA_ not modelled 45.7 24 PDB header:sugar binding protein Chain: A: PDB Molecule:cvnh-lysm lectin; PDBTitle: solution structure of the mocvnh-lysm module from the rice blast2 fungus magnaporthe oryzae protein (mgg_03307) 91 c1wu8B_ not modelled 44.6 20 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein ph0463; PDBTitle: crystal structure of project ph0463 from pyrococcus horikoshii ot3 92 c1wydB_ not modelled 44.5 15 PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii 93 d2ns0a1 not modelled 43.5 33 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:RHA1 ro06458-like 94 d1qpoa2 not modelled 41.5 21 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 95 c3a5dB_ not modelled 41.5 20 PDB header:hydrolase Chain: B: PDB Molecule:v-type atp synthase alpha chain; PDBTitle: inter-subunit interaction and quaternary rearrangement2 defined by the central stalk of prokaryotic v1-atpase 96 d1mzya2 not modelled 41.3 30 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Multidomain cupredoxins 97 c1fpyE_ not modelled 40.0 35 PDB header:ligase Chain: E: PDB Molecule:glutamine synthetase; PDBTitle: crystal structure of glutamine synthetase from salmonella2 typhimurium with inhibitor phosphinothricin 98 c1b8aB_ not modelled 39.9 22 PDB header:ligase Chain: B: PDB Molecule:protein (aspartyl-trna synthetase); PDBTitle: aspartyl-trna synthetase 99 c1htoB_ not modelled 39.2 35 PDB header:ligase Chain: B: PDB Molecule:glutamine synthetase; PDBTitle: crystallographic structure of a relaxed glutamine synthetase from2 mycobacterium tuberculosis 100 d1hcza2 not modelled 39.0 13 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 101 c2djpA_ not modelled 37.5 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein sb145; PDBTitle: the solution structure of the lysm domain of human2 hypothetical protein sb145 102 c3imiB_ not modelled 37.5 10 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hit family protein; PDBTitle: 2.01 angstrom resolution crystal structure of a hit family protein2 from bacillus anthracis str. 'ames ancestor' 103 c2ywfA_ not modelled 36.7 19 PDB header:translation Chain: A: PDB Molecule:gtp-binding protein lepa; PDBTitle: crystal structure of gmppnp-bound lepa from aquifex aeolicus 104 d2ijob1 not modelled 35.7 31 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Viral proteases 105 c3n7xA_ not modelled 35.3 23 PDB header:virus Chain: A: PDB Molecule:capsid protein; PDBTitle: crystal structure of penaeus stylirostris densovirus capsid 106 c3qr5B_ not modelled 35.3 27 PDB header:signaling protein Chain: B: PDB Molecule:cardiac ca2+ release channel; PDBTitle: structure of the first domain of a cardiac ryanodine receptor mutant2 with exon 3 deleted 107 c3o0mB_ not modelled 35.1 37 PDB header:hydrolase Chain: B: PDB Molecule:hit family protein; PDBTitle: crystal structure of a zn-bound histidine triad family protein from2 mycobacterium smegmatis 108 d1f52a2 not modelled 35.0 30 Fold:Glutamine synthetase/guanido kinase Superfamily:Glutamine synthetase/guanido kinase Family:Glutamine synthetase catalytic domain 109 d1rqpa1 not modelled 33.9 14 Fold:Bacterial fluorinating enzyme, C-terminal domain Superfamily:Bacterial fluorinating enzyme, C-terminal domain Family:Bacterial fluorinating enzyme, C-terminal domain 110 d1uwfa1 not modelled 33.9 23 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:Bacterial adhesins Family:Pilus subunits 111 d2awna2 not modelled 33.8 20 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 112 c2kcmA_ not modelled 33.8 18 PDB header:nucleic acid binding protein Chain: A: PDB Molecule:cold shock domain family protein; PDBTitle: solution nmr structure of the n-terminal ob-domain of so_1732 from2 shewanella oneidensis. northeast structural genomics consortium3 target sor210a. 113 d1k82a2 not modelled 32.8 14 Fold:N-terminal domain of MutM-like DNA repair proteins Superfamily:N-terminal domain of MutM-like DNA repair proteins Family:N-terminal domain of MutM-like DNA repair proteins 114 c2ghiD_ not modelled 32.4 34 PDB header:transport protein Chain: D: PDB Molecule:transport protein; PDBTitle: crystal structure of plasmodium yoelii multidrug resistance2 protein 2 115 c2xhaB_ not modelled 32.0 26 PDB header:transcription Chain: B: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of domain 2 of thermotoga maritima n-utilization2 substance g (nusg) 116 d3pccm_ not modelled 31.8 20 Fold:Prealbumin-like Superfamily:Aromatic compound dioxygenase Family:Aromatic compound dioxygenase 117 c1x65A_ not modelled 31.7 22 PDB header:rna binding protein Chain: A: PDB Molecule:unr protein; PDBTitle: solution structure of the third cold-shock domain of the human2 kiaa0885 protein (unr protein) 118 c3e3xA_ not modelled 31.6 15 PDB header:hydrolase Chain: A: PDB Molecule:bipa; PDBTitle: the c-terminal part of bipa protein from vibrio parahaemolyticus rimd2 2210633 119 c2quoA_ not modelled 31.1 17 PDB header:toxin Chain: A: PDB Molecule:heat-labile enterotoxin b chain; PDBTitle: crystal structure of c terminal fragment of clostridium2 perfringens enterotoxin 120 c2j9iL_ not modelled 30.7 20 PDB header:ligase Chain: L: PDB Molecule:glutamate-ammonia ligase domain-containing PDBTitle: lengsin is a survivor of an ancient family of class i2 glutamine synthetases in eukaryotes that has undergone3 evolutionary re-engineering for a tissue-specific role4 in the vertebrate eye lens.

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0