Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP38753
DateMon Jul 2 19:20:20 BST 2012
Unique Job ID574dcf2a2f45462e

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1dvpA_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine
PDBTitle: crystal structure of the vhs and fyve tandem domains of hrs,2 a protein involved in membrane trafficking and signal3 transduction
Confidence and coverage
Confidence:100.0% Coverage: 41%
187 residues ( 41% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
310 residues ( 69%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
Warning: 51% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSSSAIKIRNALLKATDPKLRSDNWQYILDVCDLVKEDPEDNGQEVMSLIEKRLEQQDAN
Secondary structure 

























SS confidence 



























































Disorder  ???????





























???



















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   .........70.........80.........90.........100.........110.........120
Sequence  VILRTLSLTVSLAENCGSRLRQEISSKNFTSLLYALIESHSVHITLKKAVTDVVKQLSDS
Secondary structure 





SS confidence 



























































Disorder 





































?????
















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   .........130.........140.........150.........160.........170.........180
Sequence  FKDDPSLRAMGDLYDKIKRKAPYLVQPNVPEKHNMSTQADNSDDEELQKALKMSLFEYEK
Secondary structure 

















SS confidence 



























































Disorder 




?

?









?

??





?
?


???????
?














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   .........190.........200.........210.........220.........230.........240
Sequence  QKKLQEQEKESAEVLPQQQQQHQQQNQAPAHKIPAQTVVRRVRALYDLTTNEPDELSFRK
Secondary structure 


















































SS confidence 



























































Disorder  ??
?
??

??
????
????????????????
???








???????????


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   .........250.........260.........270.........280.........290.........300
Sequence  GDVITVLEQVYRDWWKGALRGNMGIFPLNYVTPIVEPSKEEIEKEKNKEAIVFSQKTTID
Secondary structure 







































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Disorder 





























??????????????????????????????
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   .........310.........320.........330.........340.........350.........360
Sequence  QLHNSLNAASKTGNSNEVLQDPHIGDMYGSVTPLRPQVTRMLGKYAKEKEDMLSLRQVLA
Secondary structure 


























SS confidence 



























































Disorder  ??????????????????????
??
???????????????????
?????








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   .........370.........380.........390.........400.........410.........420
Sequence  NAERSYNQLMDRAANAHISPPVPGPALYAGMTHANNTPVMPPQRQSYQSNEYSPYPSNLP
Secondary structure 












































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Disorder 










?????????????????????????????????????????????????
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   .........430.........440.........450..
Sequence  IQHPTNSANNTPQYGYDLGYSVVSQPPPGYEQ
Secondary structure 































SS confidence 































Disorder  ????????????????????????????????
Disorder confidence 































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1dvp chain A

3D model

Region: 1 - 198
Aligned: 187
Modelled: 198
Confidence: 100.0%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine
PDBTitle: crystal structure of the vhs and fyve tandem domains of hrs,2 a protein involved in membrane trafficking and signal3 transduction

Phyre2

PDB 3zyq chain A

3D model

Region: 8 - 198
Aligned: 185
Modelled: 187
Confidence: 100.0%
Identity: 17%
PDB header:signaling
Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine kinase
PDBTitle: crystal structure of the tandem vhs and fyve domains of hepatocyte2 growth factor-regulated tyrosine kinase substrate (hgs-hrs) at 1.483 a resolution

Phyre2

PDB 1x5b chain A

3D model

Region: 4 - 156
Aligned: 151
Modelled: 153
Confidence: 100.0%
Identity: 21%
PDB header:protein binding
Chain: A: PDB Molecule:signal transducing adaptor molecule 2;
PDBTitle: the solution structure of the vhs domain of human signal2 transducing adaptor molecule 2

Phyre2

PDB 1dvp chain A domain 1

3D model

Region: 1 - 149
Aligned: 145
Modelled: 149
Confidence: 100.0%
Identity: 18%
Fold: alpha-alpha superhelix
Superfamily: ENTH/VHS domain
Family: VHS domain

Phyre2

PDB 1elk chain A

3D model

Region: 3 - 145
Aligned: 142
Modelled: 143
Confidence: 100.0%
Identity: 20%
Fold: alpha-alpha superhelix
Superfamily: ENTH/VHS domain
Family: VHS domain

Phyre2

PDB 1juq chain A

3D model

Region: 8 - 155
Aligned: 144
Modelled: 148
Confidence: 100.0%
Identity: 22%
Fold: alpha-alpha superhelix
Superfamily: ENTH/VHS domain
Family: VHS domain

Phyre2

PDB 1mhq chain A

3D model

Region: 8 - 149
Aligned: 138
Modelled: 142
Confidence: 100.0%
Identity: 20%
Fold: alpha-alpha superhelix
Superfamily: ENTH/VHS domain
Family: VHS domain

Phyre2

PDB 1ujk chain A

3D model

Region: 4 - 143
Aligned: 136
Modelled: 140
Confidence: 100.0%
Identity: 15%
Fold: alpha-alpha superhelix
Superfamily: ENTH/VHS domain
Family: VHS domain

Phyre2

PDB 3rru chain A

3D model

Region: 5 - 140
Aligned: 135
Modelled: 136
Confidence: 100.0%
Identity: 21%
PDB header:signaling protein
Chain: A: PDB Molecule:tom1l1 protein;
PDBTitle: x-ray crystal structure of the vhs domain of human tom1-like protein,2 northeast structural genomics consortium target hr3050e

Phyre2

PDB 2dcp chain A

3D model

Region: 2 - 117
Aligned: 114
Modelled: 116
Confidence: 99.8%
Identity: 17%
PDB header:unknown function
Chain: A: PDB Molecule:hypothetical protein (rafl09-17-b18);
PDBTitle: fully automated nmr structure determination of the enth-vhs2 domain at3g16270 from arabidopsis thaliana

Phyre2

PDB 1inz chain A

3D model

Region: 1 - 117
Aligned: 115
Modelled: 117
Confidence: 99.5%
Identity: 15%
Fold: alpha-alpha superhelix
Superfamily: ENTH/VHS domain
Family: ENTH domain

Phyre2

PDB 1mv3 chain A

3D model

Region: 193 - 275
Aligned: 83
Modelled: 83
Confidence: 99.4%
Identity: 25%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2

PDB 1hf8 chain A domain 2

3D model

Region: 6 - 87
Aligned: 81
Modelled: 82
Confidence: 99.3%
Identity: 16%
Fold: alpha-alpha superhelix
Superfamily: ENTH/VHS domain
Family: Phosphoinositide-binding clathrin adaptor, N-terminal domain

Phyre2

PDB 1hx8 chain A domain 2

3D model

Region: 8 - 88
Aligned: 80
Modelled: 81
Confidence: 99.3%
Identity: 19%
Fold: alpha-alpha superhelix
Superfamily: ENTH/VHS domain
Family: Phosphoinositide-binding clathrin adaptor, N-terminal domain

Phyre2

PDB 1eyh chain A

3D model

Region: 6 - 139
Aligned: 132
Modelled: 134
Confidence: 99.2%
Identity: 14%
Fold: alpha-alpha superhelix
Superfamily: ENTH/VHS domain
Family: ENTH domain

Phyre2

PDB 1gri chain A

3D model

Region: 199 - 277
Aligned: 79
Modelled: 79
Confidence: 99.1%
Identity: 35%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 2dx1 chain A

3D model

Region: 222 - 279
Aligned: 58
Modelled: 58
Confidence: 99.1%
Identity: 36%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Phyre2

PDB 2qy7 chain A

3D model

Region: 6 - 119
Aligned: 112
Modelled: 114
Confidence: 99.0%
Identity: 17%
PDB header:protein binding
Chain: A: PDB Molecule:clathrin interactor 1;
PDBTitle: crystal structure of human epsinr enth domain

Phyre2

PDB 1ng2 chain A domain 2

3D model

Region: 221 - 311
Aligned: 91
Modelled: 91
Confidence: 99.0%
Identity: 19%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 2eyz chain A

3D model

Region: 177 - 281
Aligned: 105
Modelled: 105
Confidence: 99.0%
Identity: 18%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 3nmz chain D

3D model

Region: 199 - 278
Aligned: 80
Modelled: 80
Confidence: 99.0%
Identity: 29%
PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef

Phyre2

PDB 2yun chain A

3D model

Region: 214 - 290
Aligned: 77
Modelled: 77
Confidence: 99.0%
Identity: 29%
PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin

Phyre2
1

c1dvpA_
2

c3zyqA_
3

c1x5bA_
4

d1dvpa1
5

d1elka_
6

d1juqa_
7

d1mhqa_
8

d1ujka_
9

c3rruA_
10

c2dcpA_
11

d1inza_
12

c1mv3A_
13

d1hf8a2
14

d1hx8a2
15

d1eyha_
16

c1griA_
17

c2dx1A_
18

c2qy7A_
19

d1ng2a2
20

c2eyzA_
21



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c3nmzD_
24

c2yunA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1dvpA_



100.0 16 PDB header:transferase
Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine
PDBTitle: crystal structure of the vhs and fyve tandem domains of hrs,2 a protein involved in membrane trafficking and signal3 transduction
2c3zyqA_



100.0 17 PDB header:signaling
Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine kinase
PDBTitle: crystal structure of the tandem vhs and fyve domains of hepatocyte2 growth factor-regulated tyrosine kinase substrate (hgs-hrs) at 1.483 a resolution
3c1x5bA_



100.0 21 PDB header:protein binding
Chain: A: PDB Molecule:signal transducing adaptor molecule 2;
PDBTitle: the solution structure of the vhs domain of human signal2 transducing adaptor molecule 2
4d1dvpa1



100.0 18 Fold:alpha-alpha superhelix
Superfamily:ENTH/VHS domain
Family:VHS domain
5d1elka_



100.0 20 Fold:alpha-alpha superhelix
Superfamily:ENTH/VHS domain
Family:VHS domain
6d1juqa_



100.0 22 Fold:alpha-alpha superhelix
Superfamily:ENTH/VHS domain
Family:VHS domain
7d1mhqa_



100.0 20 Fold:alpha-alpha superhelix
Superfamily:ENTH/VHS domain
Family:VHS domain
8d1ujka_



100.0 15 Fold:alpha-alpha superhelix
Superfamily:ENTH/VHS domain
Family:VHS domain
9c3rruA_



100.0 21 PDB header:signaling protein
Chain: A: PDB Molecule:tom1l1 protein;
PDBTitle: x-ray crystal structure of the vhs domain of human tom1-like protein,2 northeast structural genomics consortium target hr3050e
10c2dcpA_



99.8 17 PDB header:unknown function
Chain: A: PDB Molecule:hypothetical protein (rafl09-17-b18);
PDBTitle: fully automated nmr structure determination of the enth-vhs2 domain at3g16270 from arabidopsis thaliana
11d1inza_



99.5 15 Fold:alpha-alpha superhelix
Superfamily:ENTH/VHS domain
Family:ENTH domain
12c1mv3A_



99.4 25 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
13d1hf8a2



99.3 16 Fold:alpha-alpha superhelix
Superfamily:ENTH/VHS domain
Family:Phosphoinositide-binding clathrin adaptor, N-terminal domain
14d1hx8a2



99.3 19 Fold:alpha-alpha superhelix
Superfamily:ENTH/VHS domain
Family:Phosphoinositide-binding clathrin adaptor, N-terminal domain
15d1eyha_



99.2 14 Fold:alpha-alpha superhelix
Superfamily:ENTH/VHS domain
Family:ENTH domain
16c1griA_



99.1 35 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
17c2dx1A_



99.1 36 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
18c2qy7A_



99.0 17 PDB header:protein binding
Chain: A: PDB Molecule:clathrin interactor 1;
PDBTitle: crystal structure of human epsinr enth domain
19d1ng2a2



99.0 19 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
20c2eyzA_



99.0 18 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
21c2l3sA_



not modelled 99.0 16 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
22c3onlB_



not modelled 99.0 15 PDB header:protein transport
Chain: B: PDB Molecule:epsin-3;
PDBTitle: yeast ent3_enth-vti1p_habc complex structure
23c3nmzD_



99.0 29 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
24c2yunA_



99.0 29 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
25d1udla_



not modelled 98.9 37 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
26c2eyyA_



not modelled 98.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
27c2ed0A_



not modelled 98.9 33 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
28c1wi7A_



not modelled 98.9 32 PDB header:protein binding
Chain: A: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: solution structure of the sh3 domain of sh3-domain kinase2 binding protein 1
29c2o2oA_



not modelled 98.9 33 PDB header:protein binding
Chain: A: PDB Molecule:sh3-domain kinase-binding protein 1;
PDBTitle: solution structure of domain b from human cin85 protein
30c1xgwA_



not modelled 98.9 16 PDB header:endocytosis
Chain: A: PDB Molecule:epsin 4;
PDBTitle: the crystal structure of human enthoprotin n-terminal domain
31c1x2qA_



not modelled 98.9 32 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
32c2l0aA_



not modelled 98.9 41 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 1;
PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
33c2nwmA_



not modelled 98.9 34 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
34c2ysqA_



not modelled 98.9 34 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
35c2rqrA_



not modelled 98.9 15 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
36c2yuoA_



not modelled 98.9 36 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
37c1ng2A_



not modelled 98.9 24 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
38d1k4us_



not modelled 98.9 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
39c2dl3A_



not modelled 98.9 30 PDB header:cell adhesion, signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1
40c2ed1A_



not modelled 98.9 31 PDB header:signaling protein
Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate-
PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein
41c2dlpA_



not modelled 98.9 28 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
42c2djqA_



not modelled 98.9 35 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
43c2jxbA_



not modelled 98.9 21 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
44c2lqnA_



not modelled 98.9 14 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
45c2dmoA_



not modelled 98.9 28 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
46c2dilA_



not modelled 98.9 31 PDB header:cell adhesion
Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting
PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1
47c2dl4A_



not modelled 98.8 36 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
48c2cubA_



not modelled 98.8 32 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
49c2ebpA_



not modelled 98.8 27 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
50d2hspa_



not modelled 98.8 35 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
51c2oi3A_



not modelled 98.8 27 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
52d1uj0a_



not modelled 98.8 47 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
53c2xmfA_



not modelled 98.8 41 PDB header:motor protein
Chain: A: PDB Molecule:myosin 1e sh3;
PDBTitle: myosin 1e sh3
54c1w70A_



not modelled 98.8 45 PDB header:sh3 domain
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox
55c2ekhA_



not modelled 98.8 20 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
56c2dbkA_



not modelled 98.8 18 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
57c2dnuA_



not modelled 98.8 20 PDB header:structural genomics, structural protein
Chain: A: PDB Molecule:sh3 multiple domains 1;
PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
58c1z9qA_



not modelled 98.8 42 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: solution structure of sh3 domain of p40phox
59d1sema_



not modelled 98.8 44 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
60d1gria2



not modelled 98.8 48 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
61c2dbmA_



not modelled 98.8 38 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:sh3-containing grb2-like protein 2;
PDBTitle: solution structures of the sh3 domain of human sh3-2 containing grb2-like protein 2
62c2kymA_



not modelled 98.8 19 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
63c2pqhA_



not modelled 98.8 33 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal
64c2bz8B_



not modelled 98.8 30 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
65d1ujya_



not modelled 98.8 43 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
66c1x2pA_



not modelled 98.8 31 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 2;
PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2
67c2bzxA_



not modelled 98.8 22 PDB header:sh3 domain
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: atomic model of crkl-sh3c monomer
68d1gcqa_



not modelled 98.8 51 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
69d1ov3a2



not modelled 98.8 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
70c2yt6A_



not modelled 98.8 25 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
71c2df6A_



not modelled 98.8 45 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
72c2drmB_



not modelled 98.8 44 PDB header:contractile protein
Chain: B: PDB Molecule:acanthamoeba myosin ib;
PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125
73d1awwa_



not modelled 98.8 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
74c2eyxA_



not modelled 98.8 19 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
75c2e5kA_



not modelled 98.8 23 PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
76c2rqvA_



not modelled 98.8 16 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of sh3ci domain of bem1p
77c2egaA_



not modelled 98.8 19 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the first sh3 domain from human2 kiaa0418 protein
78c2d1xD_



not modelled 98.8 40 PDB header:cell invasion
Chain: D: PDB Molecule:cortactin isoform a;
PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex
79d1uhfa_



not modelled 98.8 35 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
80c2yupA_



not modelled 98.8 27 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
81d1utia_



not modelled 98.8 49 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
82c2dl8A_



not modelled 98.8 26 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
83c2epdA_



not modelled 98.8 35 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
84d1oeba_



not modelled 98.8 48 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
85c2eqiA_



not modelled 98.8 36 PDB header:immune system, hydrolase
Chain: A: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2
86c1zx6A_



not modelled 98.8 40 PDB header:protein binding
Chain: A: PDB Molecule:ypr154wp;
PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain
87d1ng2a1



not modelled 98.8 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
88c1zlmA_



not modelled 98.8 42 PDB header:signaling protein
Chain: A: PDB Molecule:osteoclast stimulating factor 1;
PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
89c2csqA_



not modelled 98.8 25 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
90d1awja_



not modelled 98.8 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
91d1nega_



not modelled 98.8 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
92c1negA_



not modelled 98.8 33 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin
93d1ov3a1



not modelled 98.8 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
94c3qwxX_



not modelled 98.8 22 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
95d1uuea_



not modelled 98.7 40 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
96c2js0A_



not modelled 98.7 34 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of second sh3 domain of adaptor nck
97c1x43A_



not modelled 98.7 27 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
98d1ugva_



not modelled 98.7 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
99c2fpeB_



not modelled 98.7 25 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
100d1j3ta_



not modelled 98.7 35 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
101d1phta_



not modelled 98.7 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
102c1wyxA_



not modelled 98.7 46 PDB header:cell adhesion
Chain: A: PDB Molecule:crk-associated substrate;
PDBTitle: the crystal structure of the p130cas sh3 domain at 1.1 a2 resolution
103d1uffa_



not modelled 98.7 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
104c1x69A_



not modelled 98.7 36 PDB header:signaling protein
Chain: A: PDB Molecule:cortactin isoform a;
PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin
105c2krnA_



not modelled 98.7 39 PDB header:signaling protein
Chain: A: PDB Molecule:cd2-associated protein;
PDBTitle: high resolution structure of the second sh3 domain of cd2ap
106c2i0nA_



not modelled 98.7 23 PDB header:structural protein
Chain: A: PDB Molecule:class vii unconventional myosin;
PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
107c3qwyA_



not modelled 98.7 25 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
108c2dvjA_



not modelled 98.7 21 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
109c2ke9A_



not modelled 98.7 43 PDB header:protein binding
Chain: A: PDB Molecule:caskin-2;
PDBTitle: nmr solution structure of the caskin sh3 domain
110d1pwta_



not modelled 98.7 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
111d1u06a1



not modelled 98.7 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
112c2ct3A_



not modelled 98.7 33 PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein
113d1spka_



not modelled 98.7 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
114d1wiea_



not modelled 98.7 20 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
115c3rnjA_



not modelled 98.7 33 PDB header:protein binding
Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein
PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2)
116d1ue9a_



not modelled 98.7 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
117c2csiA_



not modelled 98.7 38 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the third sh3 domain of human rim-2 binding protein 2
118d1wlpb2



not modelled 98.7 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
119d1gbra_



not modelled 98.7 35 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
120d1qlya_



not modelled 98.7 37 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain

Binding site prediction 

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below