Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ46836
DateThu Jan 5 12:35:03 GMT 2012
Unique Job IDf78d5a9abe5aba3b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3s0xB_
Top template information
PDB header:hydrolase
Chain: B: PDB Molecule:peptidase a24b, flak domain protein;
PDBTitle: the crystal structure of gxgd membrane protease flak
Confidence and coverage
Confidence: 98.7% Coverage: 52%
141 residues ( 52% of your sequence) have been modelled with 98.7% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLFDVFQQYPTAMPVLATVGGLIIGSFLNVVIWRYPIMLRQQMAEFHGEMSSAQSKISLA
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Disorder  ?





































????????????????




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   .........70.........80.........90.........100.........110.........120
Sequence  LPRSHCPHCQQTIRIRDNIPLFSWLMLKGRCRDCQAKISKRYPLVELLTALAFLLASLVW
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   .........130.........140.........150.........160.........170.........180
Sequence  PESGWGLAVMILSAWLIAASVIDLDHQWLPDVFTQGVLWTGLIAAWAQQSPLTLQDAVTG
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?








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   .........190.........200.........210.........220.........230.........240
Sequence  VLVGFITFYSLRWIAGIVLRKEALGMGDVLLFAALGGWVGALSLPNVALIASCCGLIYAV
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   .........250.........260.........
Sequence  ITKRGSTTLPFGPCLSLGGIATLYLQALF
Secondary structure 










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????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3s0x chain B

3D model

Region: 123 - 267
Aligned: 141
Modelled: 145
Confidence: 98.7%
Identity: 19%
PDB header:hydrolase
Chain: B: PDB Molecule:peptidase a24b, flak domain protein;
PDBTitle: the crystal structure of gxgd membrane protease flak

Phyre2

PDB 2owo chain A

3D model

Region: 51 - 97
Aligned: 37
Modelled: 47
Confidence: 86.6%
Identity: 16%
PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase;
PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate

Phyre2

PDB 1v9p chain B

3D model

Region: 51 - 75
Aligned: 25
Modelled: 25
Confidence: 81.9%
Identity: 12%
PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase

Phyre2

PDB 2k5c chain A

3D model

Region: 64 - 79
Aligned: 16
Modelled: 16
Confidence: 81.7%
Identity: 25%
PDB header:metal binding protein
Chain: A: PDB Molecule:uncharacterized protein pf0385;
PDBTitle: nmr structure for pf0385

Phyre2

PDB 3py7 chain A

3D model

Region: 56 - 94
Aligned: 39
Modelled: 39
Confidence: 78.6%
Identity: 21%
PDB header:viral protein
Chain: A: PDB Molecule:maltose-binding periplasmic protein,paxillin ld1,protein e6
PDBTitle: crystal structure of full-length bovine papillomavirus oncoprotein e62 in complex with ld1 motif of paxillin at 2.3a resolution

Phyre2

PDB 1dgs chain B

3D model

Region: 51 - 73
Aligned: 23
Modelled: 23
Confidence: 76.6%
Identity: 17%
PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis

Phyre2

PDB 1dgs chain A domain 1

3D model

Region: 63 - 73
Aligned: 11
Modelled: 11
Confidence: 74.9%
Identity: 27%
Fold: SAM domain-like
Superfamily: RuvA domain 2-like
Family: NAD+-dependent DNA ligase, domain 3

Phyre2

PDB 2fk4 chain A domain 1

3D model

Region: 56 - 97
Aligned: 42
Modelled: 42
Confidence: 69.5%
Identity: 19%
Fold: E6 C-terminal domain-like
Superfamily: E6 C-terminal domain-like
Family: E6 C-terminal domain-like

Phyre2

PDB 1vd4 chain A

3D model

Region: 66 - 98
Aligned: 33
Modelled: 33
Confidence: 69.2%
Identity: 27%
Fold: Rubredoxin-like
Superfamily: Zinc beta-ribbon
Family: Transcriptional factor domain

Phyre2

PDB 2fiy chain A domain 1

3D model

Region: 65 - 102
Aligned: 27
Modelled: 38
Confidence: 66.5%
Identity: 22%
Fold: FdhE-like
Superfamily: FdhE-like
Family: FdhE-like

Phyre2

PDB 2qgp chain A

3D model

Region: 86 - 102
Aligned: 17
Modelled: 17
Confidence: 66.5%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:hnh endonuclease;
PDBTitle: x-ray structure of the nhn endonuclease from geobacter2 metallireducens. northeast structural genomics consortium3 target gmr87.

Phyre2

PDB 3zyq chain A

3D model

Region: 38 - 96
Aligned: 49
Modelled: 59
Confidence: 64.9%
Identity: 18%
PDB header:signaling
Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine kinase
PDBTitle: crystal structure of the tandem vhs and fyve domains of hepatocyte2 growth factor-regulated tyrosine kinase substrate (hgs-hrs) at 1.483 a resolution

Phyre2

PDB 1vfy chain A

3D model

Region: 60 - 96
Aligned: 28
Modelled: 37
Confidence: 63.6%
Identity: 29%
Fold: FYVE/PHD zinc finger
Superfamily: FYVE/PHD zinc finger
Family: FYVE, a phosphatidylinositol-3-phosphate binding domain

Phyre2

PDB 1pfv chain A domain 3

3D model

Region: 65 - 79
Aligned: 15
Modelled: 15
Confidence: 63.0%
Identity: 27%
Fold: Rubredoxin-like
Superfamily: Methionyl-tRNA synthetase (MetRS), Zn-domain
Family: Methionyl-tRNA synthetase (MetRS), Zn-domain

Phyre2

PDB 2ea6 chain A

3D model

Region: 65 - 101
Aligned: 34
Modelled: 37
Confidence: 62.8%
Identity: 21%
PDB header:transcription
Chain: A: PDB Molecule:ring finger protein 4;
PDBTitle: solution structure of the ring domain of the human ring2 finger protein 4

Phyre2

PDB 2jne chain A domain 1

3D model

Region: 65 - 96
Aligned: 23
Modelled: 32
Confidence: 62.1%
Identity: 43%
Fold: Rubredoxin-like
Superfamily: YfgJ-like
Family: YfgJ-like

Phyre2

PDB 2jne chain A

3D model

Region: 65 - 96
Aligned: 23
Modelled: 32
Confidence: 62.1%
Identity: 43%
PDB header:metal binding protein
Chain: A: PDB Molecule:hypothetical protein yfgj;
PDBTitle: nmr structure of e.coli yfgj modelled with two zn+2 bound.2 northeast structural genomics consortium target er317.

Phyre2

PDB 2lcq chain A

3D model

Region: 62 - 74
Aligned: 13
Modelled: 13
Confidence: 62.0%
Identity: 31%
PDB header:metal binding protein
Chain: A: PDB Molecule:putative toxin vapc6;
PDBTitle: solution structure of the endonuclease nob1 from p.horikoshii

Phyre2

PDB 1wfp chain A

3D model

Region: 40 - 96
Aligned: 45
Modelled: 57
Confidence: 61.6%
Identity: 18%
Fold: AN1-like Zinc finger
Superfamily: AN1-like Zinc finger
Family: AN1-like Zinc finger

Phyre2

PDB 1dvp chain A domain 2

3D model

Region: 51 - 96
Aligned: 37
Modelled: 46
Confidence: 59.7%
Identity: 19%
Fold: FYVE/PHD zinc finger
Superfamily: FYVE/PHD zinc finger
Family: FYVE, a phosphatidylinositol-3-phosphate binding domain

Phyre2

PDB 3flo chain D

3D model

Region: 65 - 111
Aligned: 44
Modelled: 44
Confidence: 55.8%
Identity: 18%
PDB header:transferase
Chain: D: PDB Molecule:dna polymerase alpha catalytic subunit a;
PDBTitle: crystal structure of the carboxyl-terminal domain of yeast2 dna polymerase alpha in complex with its b subunit

Phyre2
1

c3s0xB_
2

c2owoA_
3

c1v9pB_
4

c2k5cA_
5

c3py7A_
6

c1dgsB_
7

d1dgsa1
8

d2fk4a1
9

d1vd4a_
10

d2fiya1
11

c2qgpA_
12

c3zyqA_
13

d1vfya_
14

d1pfva3
15

c2ea6A_
16

d2jnea1
17

c2jneA_
18

c2lcqA_
19

d1wfpa_
20

d1dvpa2
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c3floD_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3s0xB_



98.7 19 PDB header:hydrolase
Chain: B: PDB Molecule:peptidase a24b, flak domain protein;
PDBTitle: the crystal structure of gxgd membrane protease flak
2c2owoA_



86.6 16 PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase;
PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate
3c1v9pB_



81.9 12 PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase
4c2k5cA_



81.7 25 PDB header:metal binding protein
Chain: A: PDB Molecule:uncharacterized protein pf0385;
PDBTitle: nmr structure for pf0385
5c3py7A_



78.6 21 PDB header:viral protein
Chain: A: PDB Molecule:maltose-binding periplasmic protein,paxillin ld1,protein e6
PDBTitle: crystal structure of full-length bovine papillomavirus oncoprotein e62 in complex with ld1 motif of paxillin at 2.3a resolution
6c1dgsB_



76.6 17 PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis
7d1dgsa1



74.9 27 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:NAD+-dependent DNA ligase, domain 3
8d2fk4a1



69.5 19 Fold:E6 C-terminal domain-like
Superfamily:E6 C-terminal domain-like
Family:E6 C-terminal domain-like
9d1vd4a_



69.2 27 Fold:Rubredoxin-like
Superfamily:Zinc beta-ribbon
Family:Transcriptional factor domain
10d2fiya1



66.5 22 Fold:FdhE-like
Superfamily:FdhE-like
Family:FdhE-like
11c2qgpA_



66.5 18 PDB header:hydrolase
Chain: A: PDB Molecule:hnh endonuclease;
PDBTitle: x-ray structure of the nhn endonuclease from geobacter2 metallireducens. northeast structural genomics consortium3 target gmr87.
12c3zyqA_



64.9 18 PDB header:signaling
Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine kinase
PDBTitle: crystal structure of the tandem vhs and fyve domains of hepatocyte2 growth factor-regulated tyrosine kinase substrate (hgs-hrs) at 1.483 a resolution
13d1vfya_



63.6 29 Fold:FYVE/PHD zinc finger
Superfamily:FYVE/PHD zinc finger
Family:FYVE, a phosphatidylinositol-3-phosphate binding domain
14d1pfva3



63.0 27 Fold:Rubredoxin-like
Superfamily:Methionyl-tRNA synthetase (MetRS), Zn-domain
Family:Methionyl-tRNA synthetase (MetRS), Zn-domain
15c2ea6A_



62.8 21 PDB header:transcription
Chain: A: PDB Molecule:ring finger protein 4;
PDBTitle: solution structure of the ring domain of the human ring2 finger protein 4
16d2jnea1



62.1 43 Fold:Rubredoxin-like
Superfamily:YfgJ-like
Family:YfgJ-like
17c2jneA_



62.1 43 PDB header:metal binding protein
Chain: A: PDB Molecule:hypothetical protein yfgj;
PDBTitle: nmr structure of e.coli yfgj modelled with two zn+2 bound.2 northeast structural genomics consortium target er317.
18c2lcqA_



62.0 31 PDB header:metal binding protein
Chain: A: PDB Molecule:putative toxin vapc6;
PDBTitle: solution structure of the endonuclease nob1 from p.horikoshii
19d1wfpa_



61.6 18 Fold:AN1-like Zinc finger
Superfamily:AN1-like Zinc finger
Family:AN1-like Zinc finger
20d1dvpa2



59.7 19 Fold:FYVE/PHD zinc finger
Superfamily:FYVE/PHD zinc finger
Family:FYVE, a phosphatidylinositol-3-phosphate binding domain
21c3nw0A_



not modelled 59.4 18 PDB header:metal binding protein
Chain: A: PDB Molecule:non-structural maintenance of chromosomes element 1
PDBTitle: crystal structure of mageg1 and nse1 complex
22c3llkA_



not modelled 58.7 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:sulfhydryl oxidase 1;
PDBTitle: sulfhydryl oxidase fragment of human qsox1
23d1wg2a_



not modelled 58.6 18 Fold:AN1-like Zinc finger
Superfamily:AN1-like Zinc finger
Family:AN1-like Zinc finger
24c1dvpA_



not modelled 58.5 24 PDB header:transferase
Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine
PDBTitle: crystal structure of the vhs and fyve tandem domains of hrs,2 a protein involved in membrane trafficking and signal3 transduction
25d1wfka_



not modelled 57.6 36 Fold:FYVE/PHD zinc finger
Superfamily:FYVE/PHD zinc finger
Family:FYVE, a phosphatidylinositol-3-phosphate binding domain
26c2kr6A_



not modelled 57.4 21 PDB header:hydrolase
Chain: A: PDB Molecule:presenilin-1;
PDBTitle: solution structure of presenilin-1 ctf subunit
27c3floD_



55.8 18 PDB header:transferase
Chain: D: PDB Molecule:dna polymerase alpha catalytic subunit a;
PDBTitle: crystal structure of the carboxyl-terminal domain of yeast2 dna polymerase alpha in complex with its b subunit
28c3pfqA_



not modelled 55.7 18 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
29c2ecmA_



not modelled 55.1 26 PDB header:metal binding protein
Chain: A: PDB Molecule:ring finger and chy zinc finger domain-
PDBTitle: solution structure of the ring domain of the ring finger2 and chy zinc finger domain-containing protein 1 from mus3 musculus
30c3odeA_



not modelled 54.3 33 PDB header:dna binding protein/dna
Chain: A: PDB Molecule:poly [adp-ribose] polymerase 1;
PDBTitle: human parp-1 zinc finger 2 (zn2) bound to dna
31c3k1lA_



not modelled 54.3 43 PDB header:ligase
Chain: A: PDB Molecule:fancl;
PDBTitle: crystal structure of fancl
32c2dmjA_



not modelled 54.2 25 PDB header:transferase
Chain: A: PDB Molecule:poly (adp-ribose) polymerase family, member 1;
PDBTitle: solution structure of the first zf-parp domain of human2 poly(adp-ribose)polymerase-1
33c2hr5B_



not modelled 53.6 17 PDB header:metal binding protein
Chain: B: PDB Molecule:rubrerythrin;
PDBTitle: pf1283- rubrerythrin from pyrococcus furiosus iron bound form
34c2ep4A_



not modelled 53.6 21 PDB header:protein binding
Chain: A: PDB Molecule:ring finger protein 24;
PDBTitle: solution structure of ring finger from human ring finger2 protein 24
35d1wfha_



not modelled 53.5 26 Fold:AN1-like Zinc finger
Superfamily:AN1-like Zinc finger
Family:AN1-like Zinc finger
36c2kizA_



not modelled 52.8 26 PDB header:metal binding protein
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase arkadia;
PDBTitle: solution structure of arkadia ring-h2 finger domain
37c2jrpA_



not modelled 52.6 22 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative cytoplasmic protein;
PDBTitle: solution nmr structure of yfgj from salmonella typhimurium2 modeled with two zn+2 bound, northeast structural genomics3 consortium target str86
38d2baya1



not modelled 50.4 11 Fold:RING/U-box
Superfamily:RING/U-box
Family:U-box
39d2gmga1



not modelled 50.3 25 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:PF0610-like
40c1x4wA_



not modelled 50.2 35 PDB header:metal binding protein
Chain: A: PDB Molecule:hypothetical protein flj13222;
PDBTitle: solution structure of the zf-an1 domain from human2 hypothetical protein flj13222
41c1z2qA_



not modelled 49.8 16 PDB header:membrane protein
Chain: A: PDB Molecule:lm5-1;
PDBTitle: high-resolution solution structure of the lm5-1 fyve domain2 from leishmania major
42c2l0bA_



not modelled 49.6 25 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase praja-1;
PDBTitle: solution nmr structure of zinc finger domain of e3 ubiquitin-protein2 ligase praja-1 from homo sapiens, northeast structural genomics3 consortium (nesg) target hr4710b
43c2ja6L_



not modelled 49.4 28 PDB header:transferase
Chain: L: PDB Molecule:dna-directed rna polymerases i, ii, and iii 7.7
PDBTitle: cpd lesion containing rna polymerase ii elongation complex2 b
44c2k9hA_



not modelled 48.4 17 PDB header:metal binding protein
Chain: A: PDB Molecule:glycoprotein;
PDBTitle: the hantavirus glycoprotein g1 tail contains a dual cchc-2 type classical zinc fingers
45c2d8tA_



not modelled 47.4 22 PDB header:metal binding protein
Chain: A: PDB Molecule:ring finger protein 146;
PDBTitle: solution structure of the ring domain of the human ring2 finger protein 146
46d1iyma_



not modelled 46.9 20 Fold:RING/U-box
Superfamily:RING/U-box
Family:RING finger domain, C3HC4
47c2ct0A_



not modelled 46.6 20 PDB header:gene regulation
Chain: A: PDB Molecule:non-smc element 1 homolog;
PDBTitle: solution structure of the ring domain of the non-smc2 element 1 protein
48c2kdxA_



not modelled 46.5 25 PDB header:metal-binding protein
Chain: A: PDB Molecule:hydrogenase/urease nickel incorporation protein
PDBTitle: solution structure of hypa protein
49c2vjfB_



not modelled 46.4 16 PDB header:ligase
Chain: B: PDB Molecule:mdm4 protein;
PDBTitle: crystal structure of the mdm2-mdmx ring domain heterodimer
50c1dvbA_



not modelled 46.0 17 PDB header:electron transport
Chain: A: PDB Molecule:rubrerythrin;
PDBTitle: rubrerythrin
51c3axtA_



not modelled 45.4 30 PDB header:transferase
Chain: A: PDB Molecule:probable n(2),n(2)-dimethylguanosine trna methyltransferase
PDBTitle: complex structure of trna methyltransferase trm1 from aquifex aeolicus2 with s-adenosyl-l-methionine
52c2cs2A_



not modelled 45.2 33 PDB header:transferase
Chain: A: PDB Molecule:poly [adp-ribose] polymerase-1;
PDBTitle: solution structure of the second zn-finger domain of2 poly(adp-ribose) polymerase-1
53c3a44D_



not modelled 44.6 14 PDB header:metal binding protein
Chain: D: PDB Molecule:hydrogenase nickel incorporation protein hypa;
PDBTitle: crystal structure of hypa in the dimeric form
54c3h0gL_



not modelled 44.4 28 PDB header:transcription
Chain: L: PDB Molecule:dna-directed rna polymerases i, ii, and iii
PDBTitle: rna polymerase ii from schizosaccharomyces pombe
55c3bjiA_



not modelled 44.0 31 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: structural basis of promiscuous guanine nucleotide exchange2 by the t-cell essential vav1
56c3ky9B_



not modelled 43.9 29 PDB header:apoptosis
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: autoinhibited vav1
57d2ctda2



not modelled 43.9 44 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
58d2gnra1



not modelled 43.8 29 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:SSO2064-like
59c2xeuA_



not modelled 43.7 26 PDB header:transcription
Chain: A: PDB Molecule:ring finger protein 4;
PDBTitle: ring domain
60d1rmda2



not modelled 43.7 35 Fold:RING/U-box
Superfamily:RING/U-box
Family:RING finger domain, C3HC4
61d2ayja1



not modelled 43.6 17 Fold:Rubredoxin-like
Superfamily:Zn-binding ribosomal proteins
Family:Ribosomal protein L40e
62c1v9xA_



not modelled 42.7 25 PDB header:transferase
Chain: A: PDB Molecule:poly (adp-ribose) polymerase;
PDBTitle: solution structure of the first zn-finger domain of2 poly(adp-ribose) polymerase-1
63c2djbA_



not modelled 42.5 16 PDB header:gene regulation
Chain: A: PDB Molecule:polycomb group ring finger protein 6;
PDBTitle: solution structure of the ring domain of the human polycomb2 group ring finger protein 6
64c1x4jA_



not modelled 42.0 24 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:ring finger protein 38;
PDBTitle: solution structure of ring finger in ring finger protein 38
65c2qkdA_



not modelled 41.9 24 PDB header:signaling protein, cell cycle
Chain: A: PDB Molecule:zinc finger protein zpr1;
PDBTitle: crystal structure of tandem zpr1 domains
66c2f9iD_



not modelled 41.9 16 PDB header:transferase
Chain: D: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl
PDBTitle: crystal structure of the carboxyltransferase subunit of acc2 from staphylococcus aureus
67d1faqa_



not modelled 41.4 37 Fold:Cysteine-rich domain
Superfamily:Cysteine-rich domain
Family:Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)
68c2ectA_



not modelled 41.4 19 PDB header:metal binding protein
Chain: A: PDB Molecule:ring finger protein 126;
PDBTitle: solution structure of the zinc finger, c3hc4 type (ring2 finger) domain of ring finger protein 126
69c2i5oA_



not modelled 41.2 25 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase eta;
PDBTitle: solution structure of the ubiquitin-binding zinc finger2 (ubz) domain of the human dna y-polymerase eta
70c3cngC_



not modelled 41.0 20 PDB header:hydrolase
Chain: C: PDB Molecule:nudix hydrolase;
PDBTitle: crystal structure of nudix hydrolase from nitrosomonas europaea
71c2f42A_



not modelled 40.8 17 PDB header:chaperone
Chain: A: PDB Molecule:stip1 homology and u-box containing protein 1;
PDBTitle: dimerization and u-box domains of zebrafish c-terminal of hsp702 interacting protein
72c3lrqB_



not modelled 40.7 32 PDB header:ligase
Chain: B: PDB Molecule:e3 ubiquitin-protein ligase trim37;
PDBTitle: crystal structure of the u-box domain of human ubiquitin-2 protein ligase (e3), northeast structural genomics3 consortium target hr4604d.
73d1uw0a_



not modelled 40.6 33 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:PARP-type zinc finger
74c2zkr2_



not modelled 40.4 23 PDB header:ribosomal protein/rna
Chain: 2: PDB Molecule:60s ribosomal protein l37e;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
75d1vqo11



not modelled 39.5 30 Fold:Rubredoxin-like
Superfamily:Zn-binding ribosomal proteins
Family:Ribosomal protein L37e
76d1wjva1



not modelled 39.2 26 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:C2HC finger
77c2rowA_



not modelled 39.1 35 PDB header:transferase
Chain: A: PDB Molecule:rho-associated protein kinase 2;
PDBTitle: the c1 domain of rock ii
78c3tsuA_



not modelled 38.8 12 PDB header:transferase
Chain: A: PDB Molecule:transcriptional regulatory protein;
PDBTitle: crystal structure of e. coli hypf with amp-pnp and carbamoyl phosphate
79d1wffa_



not modelled 38.5 28 Fold:AN1-like Zinc finger
Superfamily:AN1-like Zinc finger
Family:AN1-like Zinc finger
80c3t7lA_



not modelled 38.5 22 PDB header:transport protein
Chain: A: PDB Molecule:zinc finger fyve domain-containing protein 16;
PDBTitle: crystal structure of the fyve domain of endofin (zfyve16) at 1.1a2 resolution
81d2cu8a1



not modelled 38.4 36 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
82d2ct1a1



not modelled 38.1 60 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
83c2jr6A_



not modelled 37.7 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:upf0434 protein nma0874;
PDBTitle: solution structure of upf0434 protein nma0874. northeast structural2 genomics target mr32
84c2pmzB_



not modelled 37.6 19 PDB header:translation, transferase
Chain: B: PDB Molecule:dna-directed rna polymerase subunit b;
PDBTitle: archaeal rna polymerase from sulfolobus solfataricus
85c2jmdA_



not modelled 37.4 17 PDB header:ligase
Chain: A: PDB Molecule:tnf receptor-associated factor 6;
PDBTitle: solution structure of the ring domain of human traf6
86c3jywY_



not modelled 35.8 36 PDB header:ribosome
Chain: Y: PDB Molecule:60s ribosomal protein l37(a);
PDBTitle: structure of the 60s proteins for eukaryotic ribosome based on cryo-em2 map of thermomyces lanuginosus ribosome at 8.9a resolution
87d1tjla2



not modelled 35.7 33 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:Prokaryotic DksA/TraR C4-type zinc finger
88d1q1aa_



not modelled 35.5 17 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Sir2 family of transcriptional regulators
89d1xa6a3



not modelled 35.4 35 Fold:Cysteine-rich domain
Superfamily:Cysteine-rich domain
Family:Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)
90c1jocA_



not modelled 35.3 28 PDB header:membrane protein
Chain: A: PDB Molecule:early endosomal autoantigen 1;
PDBTitle: eea1 homodimer of c-terminal fyve domain bound to inositol2 1,3-diphosphate
91c2y43B_



not modelled 35.0 14 PDB header:ligase
Chain: B: PDB Molecule:e3 ubiquitin-protein ligase rad18;
PDBTitle: rad18 ubiquitin ligase ring domain structure
92c1hk8A_



not modelled 33.7 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:anaerobic ribonucleotide-triphosphate reductase;
PDBTitle: structural basis for allosteric substrate specificity2 regulation in class iii ribonucleotide reductases:3 nrdd in complex with dgtp
93d1hk8a_



not modelled 33.7 27 Fold:PFL-like glycyl radical enzymes
Superfamily:PFL-like glycyl radical enzymes
Family:Class III anaerobic ribonucleotide reductase NRDD subunit
94c3t6pA_



not modelled 33.7 40 PDB header:apoptosis
Chain: A: PDB Molecule:baculoviral iap repeat-containing protein 2;
PDBTitle: iap antagonist-induced conformational change in ciap1 promotes e32 ligase activation via dimerization
95c1s1iY_



not modelled 33.6 36 PDB header:ribosome
Chain: Y: PDB Molecule:60s ribosomal protein l37-a;
PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1i,4 contains 60s subunit. the 40s ribosomal subunit is in file5 1s1h.
96c2db6A_



not modelled 33.5 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 and cysteine rich domain 3;
PDBTitle: solution structure of rsgi ruh-051, a c1 domain of stac32 from human cdna
97d1s5pa_



not modelled 32.9 8 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Sir2 family of transcriptional regulators
98c2csyA_



not modelled 32.8 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:zinc finger protein 183-like 1;
PDBTitle: solution structure of the ring domain of the zinc finger2 protein 183-like 1
99d2cona1



not modelled 32.7 36 Fold:Rubredoxin-like
Superfamily:NOB1 zinc finger-like
Family:NOB1 zinc finger-like
100d1chca_



not modelled 32.3 16 Fold:RING/U-box
Superfamily:RING/U-box
Family:RING finger domain, C3HC4
101c2eluA_



not modelled 32.0 50 PDB header:transcription
Chain: A: PDB Molecule:zinc finger protein 406;
PDBTitle: solution structure of the 5th c2h2 zinc finger of human2 zinc finger protein 406
102c2ecvA_



not modelled 31.5 24 PDB header:ligase
Chain: A: PDB Molecule:tripartite motif-containing protein 5;
PDBTitle: solution structure of the zinc finger, c3hc4 type (ring2 finger) domain of tripartite motif-containing protein 5
103d1zbdb_



not modelled 31.4 18 Fold:FYVE/PHD zinc finger
Superfamily:FYVE/PHD zinc finger
Family:FYVE, a phosphatidylinositol-3-phosphate binding domain
104c2eciA_



not modelled 31.4 16 PDB header:metal binding protein
Chain: A: PDB Molecule:tnf receptor-associated factor 6;
PDBTitle: solution structure of the ring domain of the human tnf2 receptor-associated factor 6 protein
105c1u5kA_



not modelled 31.0 18 PDB header:recombination,replication
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: recombinational repair protein reco
106c2kgoA_



not modelled 30.9 36 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein ybii;
PDBTitle: solution nmr structure of zn finger protein ybil from escherichia2 coli. nesg target et107, ocsp target ec0402
107c1z6uA_



not modelled 30.8 19 PDB header:ligase
Chain: A: PDB Molecule:np95-like ring finger protein isoform b;
PDBTitle: np95-like ring finger protein isoform b [homo sapiens]
108d1jm7a_



not modelled 30.8 32 Fold:RING/U-box
Superfamily:RING/U-box
Family:RING finger domain, C3HC4
109d2c2la2



not modelled 30.7 17 Fold:RING/U-box
Superfamily:RING/U-box
Family:U-box
110c1tjlD_



not modelled 30.7 33 PDB header:transcription
Chain: D: PDB Molecule:dnak suppressor protein;
PDBTitle: crystal structure of transcription factor dksa from e. coli
111d1wfla_



not modelled 29.9 19 Fold:AN1-like Zinc finger
Superfamily:AN1-like Zinc finger
Family:AN1-like Zinc finger
112c3u50C_



not modelled 29.9 19 PDB header:dna binding protein
Chain: C: PDB Molecule:telomerase-associated protein 82;
PDBTitle: crystal structure of the tetrahymena telomerase processivity factor2 teb1 ob-c
113d1x3ha1



not modelled 29.7 23 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
114c2hcnA_



not modelled 29.5 22 PDB header:transferase
Chain: A: PDB Molecule:rna-directed rna polymerase (ns5);
PDBTitle: crystal structure of rna dependent rna polymerase domain from west2 nile virus
115d1iyca_



not modelled 29.4 35 Fold:Invertebrate chitin-binding proteins
Superfamily:Invertebrate chitin-binding proteins
Family:Antifungal peptide scarabaecin
116c2cszA_



not modelled 29.0 19 PDB header:signaling protein
Chain: A: PDB Molecule:synaptotagmin-like protein 4;
PDBTitle: solution structure of the ring domain of the synaptotagmin-2 like protein 4
117d1kbea_



not modelled 28.9 33 Fold:Cysteine-rich domain
Superfamily:Cysteine-rich domain
Family:Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)
118d1yc5a1



not modelled 28.7 23 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Sir2 family of transcriptional regulators
119c2klxA_



not modelled 28.5 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:glutaredoxin;
PDBTitle: solution structure of glutaredoxin from bartonella henselae str.2 houston
120d1dsva_



not modelled 28.4 29 Fold:Retrovirus zinc finger-like domains
Superfamily:Retrovirus zinc finger-like domains
Family:Retrovirus zinc finger-like domains

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0