Secondary structure and disorder prediction

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Sequence		M	T	S	P	V	N	V	D	V	K	L	G	V	N	K	F	N	V	D	E	E	H	P	H	I	V	V	K	A	D	A	D	K	Q	A	L	E	L	L	V	K	A	C	P	A	G	L	Y	K	K	Q	D	D	G	S	V	R	F	D	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.
Sequence		A	G	C	L	E	C	G	T	C	R	I	L	G	L	G	S	A	L	E	Q	W	E	Y	P	R	G	T	F	G	V	E	F	R	Y	G
Secondary structure
SS confidence
Disorder																														?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2gmh chain A domain 3 Region: 6 - 94 Aligned: 88 Modelled: 89 Confidence: 99.8% Identity: 19% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: ETF-QO domain-like Phyre2 PDB 2gmh chain A Region: 17 - 94 Aligned: 76 Modelled: 78 Confidence: 99.7% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:electron transfer flavoprotein-ubiquinone PDBTitle: structure of porcine electron transfer flavoprotein-2 ubiquinone oxidoreductase in complexed with ubiquinone Phyre2 PDB 2ivf chain B Region: 19 - 86 Aligned: 67 Modelled: 68 Confidence: 99.5% Identity: 21% PDB header:oxidoreductase Chain: B: PDB Molecule:ethylbenzene dehydrogenase beta-subunit; PDBTitle: ethylbenzene dehydrogenase from aromatoleum aromaticum Phyre2 PDB 1y5i chain B domain 1 Region: 14 - 86 Aligned: 72 Modelled: 73 Confidence: 99.4% Identity: 19% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 PDB 1gth chain D Region: 26 - 79 Aligned: 53 Modelled: 54 Confidence: 99.3% Identity: 9% PDB header:oxidoreductase Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase; PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil Phyre2 PDB 1ti2 chain F Region: 27 - 86 Aligned: 58 Modelled: 60 Confidence: 99.3% Identity: 12% PDB header:oxidoreductase Chain: F: PDB Molecule:pyrogallol hydroxytransferase small subunit; PDBTitle: crystal structure of pyrogallol-phloroglucinol2 transhydroxylase from pelobacter acidigallici Phyre2 PDB 1hfe chain L domain 2 Region: 20 - 80 Aligned: 60 Modelled: 61 Confidence: 99.3% Identity: 12% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 PDB 7fd1 chain A Region: 27 - 79 Aligned: 52 Modelled: 53 Confidence: 99.3% Identity: 17% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: 7-Fe ferredoxin Phyre2 PDB 3gyx chain J Region: 25 - 79 Aligned: 54 Modelled: 55 Confidence: 99.2% Identity: 19% PDB header:oxidoreductase Chain: J: PDB Molecule:adenylylsulfate reductase; PDBTitle: crystal structure of adenylylsulfate reductase from2 desulfovibrio gigas Phyre2 PDB 1hfe chain L Region: 9 - 82 Aligned: 73 Modelled: 74 Confidence: 99.2% Identity: 10% PDB header:hydrogenase Chain: L: PDB Molecule:protein (fe-only hydrogenase (e.c.1.18.99.1) PDBTitle: 1.6 a resolution structure of the fe-only hydrogenase from2 desulfovibrio desulfuricans Phyre2 PDB 3c7b chain B domain 1 Region: 22 - 83 Aligned: 62 Modelled: 62 Confidence: 99.2% Identity: 27% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 PDB 2fug chain G Region: 19 - 79 Aligned: 60 Modelled: 61 Confidence: 99.2% Identity: 22% PDB header:oxidoreductase Chain: G: PDB Molecule:nadh-quinone oxidoreductase chain 9; PDBTitle: crystal structure of the hydrophilic domain of respiratory complex i2 from thermus thermophilus Phyre2 PDB 2fug chain 9 domain 1 Region: 19 - 79 Aligned: 60 Modelled: 61 Confidence: 99.2% Identity: 22% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 PDB 1jnr chain B Region: 26 - 79 Aligned: 54 Modelled: 54 Confidence: 99.2% Identity: 19% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 PDB 1bc6 chain A Region: 27 - 79 Aligned: 52 Modelled: 53 Confidence: 99.2% Identity: 23% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: 7-Fe ferredoxin Phyre2 PDB 1h98 chain A Region: 26 - 84 Aligned: 58 Modelled: 58 Confidence: 99.2% Identity: 19% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: 7-Fe ferredoxin Phyre2 PDB 1gx7 chain A Region: 24 - 82 Aligned: 58 Modelled: 59 Confidence: 99.2% Identity: 12% PDB header:oxidoreductase Chain: A: PDB Molecule:periplasmic [fe] hydrogenase large subunit; PDBTitle: best model of the electron transfer complex between2 cytochrome c3 and [fe]-hydrogenase Phyre2 PDB 1xer chain A Region: 22 - 84 Aligned: 61 Modelled: 63 Confidence: 99.2% Identity: 20% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Archaeal ferredoxins Phyre2 PDB 1kqf chain B Region: 19 - 86 Aligned: 67 Modelled: 68 Confidence: 99.2% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:formate dehydrogenase, nitrate-inducible, iron-sulfur PDBTitle: formate dehydrogenase n from e. coli Phyre2 PDB 1kqf chain B domain 1 Region: 19 - 86 Aligned: 67 Modelled: 68 Confidence: 99.2% Identity: 19% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 1 d2gmha3 2 c2gmhA_ 3 c2ivfB_ 4 d1y5ib1 5 c1gthD_ 6 c1ti2F_ 7 d1hfel2 8 d7fd1a_ 9 c3gyxJ_ 10 c1hfeL_ 11 d3c7bb1 12 c2fugG_ 13 d2fug91 14 d1jnrb_ 15 d1bc6a_ 16 d1h98a_ 17 c1gx7A_ 18 d1xera_ 19 c1kqfB_ 20 d1kqfb1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2gmha3 99.8 19 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:ETF-QO domain-like 2 c2gmhA_ 99.7 21 PDB header:oxidoreductase Chain: A: PDB Molecule:electron transfer flavoprotein-ubiquinone PDBTitle: structure of porcine electron transfer flavoprotein-2 ubiquinone oxidoreductase in complexed with ubiquinone 3 c2ivfB_ 99.5 21 PDB header:oxidoreductase Chain: B: PDB Molecule:ethylbenzene dehydrogenase beta-subunit; PDBTitle: ethylbenzene dehydrogenase from aromatoleum aromaticum 4 d1y5ib1 99.4 19 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 5 c1gthD_ 99.3 9 PDB header:oxidoreductase Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase; PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil 6 c1ti2F_ 99.3 12 PDB header:oxidoreductase Chain: F: PDB Molecule:pyrogallol hydroxytransferase small subunit; PDBTitle: crystal structure of pyrogallol-phloroglucinol2 transhydroxylase from pelobacter acidigallici 7 d1hfel2 99.3 12 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 8 d7fd1a_ 99.3 17 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:7-Fe ferredoxin 9 c3gyxJ_ 99.2 19 PDB header:oxidoreductase Chain: J: PDB Molecule:adenylylsulfate reductase; PDBTitle: crystal structure of adenylylsulfate reductase from2 desulfovibrio gigas 10 c1hfeL_ 99.2 10 PDB header:hydrogenase Chain: L: PDB Molecule:protein (fe-only hydrogenase (e.c.1.18.99.1) PDBTitle: 1.6 a resolution structure of the fe-only hydrogenase from2 desulfovibrio desulfuricans 11 d3c7bb1 99.2 27 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 12 c2fugG_ 99.2 22 PDB header:oxidoreductase Chain: G: PDB Molecule:nadh-quinone oxidoreductase chain 9; PDBTitle: crystal structure of the hydrophilic domain of respiratory complex i2 from thermus thermophilus 13 d2fug91 99.2 22 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 14 d1jnrb_ 99.2 19 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 15 d1bc6a_ 99.2 23 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:7-Fe ferredoxin 16 d1h98a_ 99.2 19 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:7-Fe ferredoxin 17 c1gx7A_ 99.2 12 PDB header:oxidoreductase Chain: A: PDB Molecule:periplasmic [fe] hydrogenase large subunit; PDBTitle: best model of the electron transfer complex between2 cytochrome c3 and [fe]-hydrogenase 18 d1xera_ 99.2 20 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Archaeal ferredoxins 19 c1kqfB_ 99.2 19 PDB header:oxidoreductase Chain: B: PDB Molecule:formate dehydrogenase, nitrate-inducible, iron-sulfur PDBTitle: formate dehydrogenase n from e. coli 20 d1kqfb1 99.2 19 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 21 c3bk7A_ not modelled 99.1 22 PDB header:hydrolyase/translation Chain: A: PDB Molecule:abc transporter atp-binding protein; PDBTitle: structure of the complete abce1/rnaase-l inhibitor protein2 from pyrococcus abysii 22 c2vpyB_ not modelled 99.1 19 PDB header:oxidoreductase Chain: B: PDB Molecule:nrfc protein; PDBTitle: polysulfide reductase with bound quinone inhibitor,2 pentachlorophenol (pcp) 23 d3c8ya3 not modelled 99.1 26 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 24 d1fcaa_ not modelled 99.1 23 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Short-chain ferredoxins 25 d2fdna_ not modelled 99.1 23 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Short-chain ferredoxins 26 d1gtea5 not modelled 99.1 12 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 27 c2c3yA_ not modelled 99.1 18 PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate-ferredoxin oxidoreductase; PDBTitle: crystal structure of the radical form of2 pyruvate:ferredoxin oxidoreductase from desulfovibrio3 africanus 28 c2v2kB_ not modelled 99.1 16 PDB header:electron transport Chain: B: PDB Molecule:ferredoxin; PDBTitle: the crystal structure of fdxa, a 7fe ferredoxin from2 mycobacterium smegmatis 29 d1dura_ not modelled 99.1 22 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Short-chain ferredoxins 30 d1jb0c_ not modelled 99.0 23 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:7-Fe ferredoxin 31 d1clfa_ not modelled 99.0 22 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Short-chain ferredoxins 32 c2zvsB_ not modelled 98.9 15 PDB header:electron transport Chain: B: PDB Molecule:uncharacterized ferredoxin-like protein yfhl; PDBTitle: crystal structure of the 2[4fe-4s] ferredoxin from escherichia coli 33 d1vlfn2 not modelled 98.9 12 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 34 d2fug34 not modelled 98.9 11 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 35 c2fgoA_ not modelled 98.9 17 PDB header:electron transport Chain: A: PDB Molecule:ferredoxin; PDBTitle: structure of the 2[4fe-4s] ferredoxin from pseudomonas2 aeruginosa 36 c1c4cA_ not modelled 98.9 31 PDB header:oxidoreductase Chain: A: PDB Molecule:protein (fe-only hydrogenase); PDBTitle: binding of exogenously added carbon monoxide at the active2 site of the fe-only hydrogenase (cpi) from clostridium3 pasteurianum 37 d1blua_ not modelled 98.9 17 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Short-chain ferredoxins 38 c3c7bE_ not modelled 98.8 25 PDB header:oxidoreductase Chain: E: PDB Molecule:sulfite reductase, dissimilatory-type subunit beta; PDBTitle: structure of the dissimilatory sulfite reductase from archaeoglobus2 fulgidus 39 d1rgva_ not modelled 98.8 22 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Short-chain ferredoxins 40 d2c42a5 not modelled 98.8 18 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 41 d1h0hb_ not modelled 98.8 7 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 42 c2v4jE_ not modelled 98.8 20 PDB header:oxidoreductase Chain: E: PDB Molecule:sulfite reductase, dissimilatory-type subunit PDBTitle: the crystal structure of desulfovibrio vulgaris2 dissimilatory sulfite reductase bound to dsrc provides3 novel insights into the mechanism of sulfate respiration 43 d1iqza_ not modelled 98.7 11 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Single 4Fe-4S cluster ferredoxin 44 d1vjwa_ not modelled 98.7 17 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Single 4Fe-4S cluster ferredoxin 45 c3c7bA_ not modelled 98.6 26 PDB header:oxidoreductase Chain: A: PDB Molecule:sulfite reductase, dissimilatory-type subunit alpha; PDBTitle: structure of the dissimilatory sulfite reductase from archaeoglobus2 fulgidus 46 c2v4jA_ not modelled 98.5 20 PDB header:oxidoreductase Chain: A: PDB Molecule:sulfite reductase, dissimilatory-type subunit PDBTitle: the crystal structure of desulfovibrio vulgaris2 dissimilatory sulfite reductase bound to dsrc provides3 novel insights into the mechanism of sulfate respiration 47 c1dwlA_ not modelled 98.5 14 PDB header:electron transfer Chain: A: PDB Molecule:ferredoxin i; PDBTitle: the ferredoxin-cytochrome complex using heteronuclear nmr2 and docking simulation 48 c2fugC_ not modelled 98.3 11 PDB header:oxidoreductase Chain: C: PDB Molecule:nadh-quinone oxidoreductase chain 3; PDBTitle: crystal structure of the hydrophilic domain of respiratory complex i2 from thermus thermophilus 49 d1sj1a_ not modelled 98.2 13 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Single 4Fe-4S cluster ferredoxin 50 d1fxra_ not modelled 98.1 18 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Single 4Fe-4S cluster ferredoxin 51 d2v4jb1 not modelled 97.5 20 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 52 d2v4ja1 not modelled 96.6 24 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 53 d3c7ba1 not modelled 96.5 29 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Ferredoxin domains from multidomain proteins 54 d1kf6b1 not modelled 96.3 23 Fold:Globin-like Superfamily:alpha-helical ferredoxin Family:Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain 55 d2bs2b1 not modelled 96.2 17 Fold:Globin-like Superfamily:alpha-helical ferredoxin Family:Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain 56 d1nekb1 not modelled 95.7 15 Fold:Globin-like Superfamily:alpha-helical ferredoxin Family:Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain 57 c2bs2E_ not modelled 95.5 14 PDB header:oxidoreductase Chain: E: PDB Molecule:quinol-fumarate reductase iron-sulfur subunit b; PDBTitle: quinol:fumarate reductase from wolinella succinogenes 58 c1nekB_ not modelled 95.4 15 PDB header:oxidoreductase/electron transport Chain: B: PDB Molecule:succinate dehydrogenase iron-sulfur protein; PDBTitle: complex ii (succinate dehydrogenase) from e. coli with2 ubiquinone bound 59 c2b76N_ not modelled 95.1 25 PDB header:oxidoreductase Chain: N: PDB Molecule:fumarate reductase iron-sulfur protein; PDBTitle: e. coli quinol fumarate reductase frda e49q mutation 60 c3cf4A_ not modelled 94.7 17 PDB header:oxidoreductase Chain: A: PDB Molecule:acetyl-coa decarboxylase/synthase alpha subunit; PDBTitle: structure of the codh component of the m. barkeri acds complex 61 c2h89B_ not modelled 87.7 15 PDB header:oxidoreductase Chain: B: PDB Molecule:succinate dehydrogenase ip subunit; PDBTitle: avian respiratory complex ii with malonate bound 62 d1fxda_ not modelled 79.8 26 Fold:Ferredoxin-like Superfamily:4Fe-4S ferredoxins Family:Single 4Fe-4S cluster ferredoxin 63 c2vdcI_ not modelled 68.5 29 PDB header:oxidoreductase Chain: I: PDB Molecule:glutamate synthase [nadph] small chain; PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications. 64 c1g8jC_ not modelled 37.9 15 PDB header:oxidoreductase Chain: C: PDB Molecule:arsenite oxidase; PDBTitle: crystal structure analysis of arsenite oxidase from2 alcaligenes faecalis 65 c2pmzS_ not modelled 25.7 22 PDB header:translation, transferase Chain: S: PDB Molecule:dna-directed rna polymerase subunit d; PDBTitle: archaeal rna polymerase from sulfolobus solfataricus 66 d1g8ka2 not modelled 17.3 17 Fold:Formate dehydrogenase/DMSO reductase, domains 1-3 Superfamily:Formate dehydrogenase/DMSO reductase, domains 1-3 Family:Formate dehydrogenase/DMSO reductase, domains 1-3 67 d1gtea1 not modelled 15.6 24 Fold:Globin-like Superfamily:alpha-helical ferredoxin Family:Dihydropyrimidine dehydrogenase, N-terminal domain 68 d1h6ua1 not modelled 14.9 13 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Internalin Ig-like domain 69 d1h6ta1 not modelled 11.7 31 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Internalin Ig-like domain 70 d1j9ia_ not modelled 10.6 40 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:Terminase gpNU1 subunit domain 71 d2omza1 not modelled 10.2 25 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Internalin Ig-like domain 72 c1igrA_ not modelled 8.2 24 PDB header:hormone receptor Chain: A: PDB Molecule:insulin-like growth factor receptor 1; PDBTitle: type 1 insulin-like growth factor receptor (domains 1-3) 73 d1qpma_ not modelled 6.2 30 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:Excisionase-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0