Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	T	V	Y	T	L	V	S	W	L	A	I	L	G	Y	W	L	L	I	A	G	V	T	L	R	I	L	M	K	R	R	A	V	P	S	A	M	A	W	L	L	I	I	Y	I	L	P	L	V	G	I	I	A	Y	L	A	V	G	E
Secondary structure
SS confidence
Disorder		?	?	?																											?																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	H	L	G	K	R	R	A	E	R	A	R	A	M	W	P	S	T	A	K	W	L	N	D	L	K	A	C	K	H	I	F	A	E	E	N	S	S	V	A	A	P	L	F	K	L	C	E	R	R	Q	G	I	A	G	V	K	G	N	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?																		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	Q	L	M	T	E	S	D	D	V	M	Q	A	L	I	R	D	I	Q	L	A	R	H	N	I	E	M	V	F	Y	I	W	Q	P	G	G	M	A	D	Q	V	A	E	S	L	M	A	A	A	R	R	G	I	H	C	R	L	M	L	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	A	G	S	V	A	F	F	R	S	P	W	P	E	L	M	R	N	A	G	I	E	V	V	E	A	L	K	V	N	L	M	R	V	F	L	R	R	M	D	L	R	Q	H	R	K	M	I	M	I	D	N	Y	I	A	Y	T	G	S	M
Secondary structure
SS confidence
Disorder										?																						?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		N	M	V	D	P	R	Y	F	K	Q	D	A	G	V	G	Q	W	I	D	L	M	A	R	M	E	G	P	I	A	T	A	M	G	I	I	Y	S	C	D	W	E	I	E	T	G	K	R	I	L	P	P	P	P	D	V	N	I	M	P	F
Secondary structure
SS confidence
Disorder										?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		E	Q	A	S	G	H	T	I	H	T	I	A	S	G	P	G	F	P	E	D	L	I	H	Q	A	L	L	T	A	A	Y	S	A	R	E	Y	L	I	M	T	T	P	Y	F	V	P	S	D	D	L	L	H	A	I	C	T	A	A	Q	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	V	D	V	S	I	I	L	P	R	K	N	D	S	M	L	V	G	W	A	S	R	A	F	F	T	E	L	L	A	A	G	V	K	I	Y	Q	F	E	G	G	L	L	H	T	K	S	V	L	V	D	G	E	L	S	L	V	G	T	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		N	L	D	M	R	S	L	W	L	N	F	E	I	T	L	A	I	D	D	K	G	F	G	A	D	L	A	A	V	Q	D	D	Y	I	S	R	S	R	L	L	D	A	R	L	W	L	K	R	P	L	W	Q	R	V	A	E	R	L	F	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.
Sequence		F	F	S	P	L	L
Secondary structure
SS confidence
Disorder					?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3hsi chain C Region: 100 - 486 Aligned: 382 Modelled: 385 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: C: PDB Molecule:phosphatidylserine synthase; PDBTitle: crystal structure of phosphatidylserine synthase haemophilus2 influenzae rd kw20 Phyre2 PDB 1v0s chain A Region: 115 - 467 Aligned: 346 Modelled: 353 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:phospholipase d; PDBTitle: uninhibited form of phospholipase d from streptomyces sp.2 strain pmf Phyre2 PDB 1xdo chain B Region: 123 - 459 Aligned: 278 Modelled: 291 Confidence: 100.0% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of escherichia coli polyphosphate kinase Phyre2 PDB 1v0w chain A domain 1 Region: 125 - 292 Aligned: 165 Modelled: 168 Confidence: 100.0% Identity: 15% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Phospholipase D Phyre2 PDB 1xdp chain A domain 3 Region: 310 - 463 Aligned: 151 Modelled: 154 Confidence: 99.9% Identity: 19% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 1byr chain A Region: 305 - 460 Aligned: 148 Modelled: 156 Confidence: 99.9% Identity: 23% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Nuclease Phyre2 PDB 2o8r chain A Region: 123 - 459 Aligned: 279 Modelled: 293 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of polyphosphate kinase from2 porphyromonas gingivalis Phyre2 PDB 1v0w chain A domain 2 Region: 321 - 467 Aligned: 144 Modelled: 147 Confidence: 99.9% Identity: 23% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Phospholipase D Phyre2 PDB 2o8r chain A domain 3 Region: 310 - 459 Aligned: 144 Modelled: 150 Confidence: 99.1% Identity: 22% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 1xdp chain A domain 4 Region: 315 - 459 Aligned: 129 Modelled: 130 Confidence: 99.1% Identity: 15% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 2o8r chain A domain 4 Region: 314 - 459 Aligned: 132 Modelled: 146 Confidence: 98.9% Identity: 11% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 1q32 chain C Region: 223 - 437 Aligned: 213 Modelled: 215 Confidence: 97.7% Identity: 13% PDB header:replication,transcription,hydrolase Chain: C: PDB Molecule:tyrosyl-dna phosphodiesterase; PDBTitle: crystal structure analysis of the yeast tyrosyl-dna2 phosphodiesterase Phyre2 PDB 2c1l chain A Region: 350 - 444 Aligned: 92 Modelled: 95 Confidence: 97.6% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:restriction endonuclease; PDBTitle: structure of the bfii restriction endonuclease Phyre2 PDB 3sq3 chain C Region: 223 - 437 Aligned: 213 Modelled: 215 Confidence: 97.2% Identity: 15% PDB header:hydrolase Chain: C: PDB Molecule:tyrosyl-dna phosphodiesterase 1; PDBTitle: crystal structure analysis of the yeast tyrosyl-dna phosphodiesterase2 h182a mutant Phyre2 PDB 1jy1 chain A domain 2 Region: 399 - 437 Aligned: 39 Modelled: 39 Confidence: 95.3% Identity: 18% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Tyrosyl-DNA phosphodiesterase TDP1 Phyre2 PDB 1nop chain B Region: 399 - 437 Aligned: 39 Modelled: 39 Confidence: 95.1% Identity: 23% PDB header:hydrolase/dna Chain: B: PDB Molecule:tyrosyl-dna phosphodiesterase 1; PDBTitle: crystal structure of human tyrosyl-dna phosphodiesterase2 (tdp1) in complex with vanadate, dna and a human3 topoisomerase i-derived peptide Phyre2 PDB 1q32 chain A domain 2 Region: 403 - 437 Aligned: 35 Modelled: 35 Confidence: 94.6% Identity: 23% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Tyrosyl-DNA phosphodiesterase TDP1 Phyre2 PDB 2f5t chain X domain 2 Region: 317 - 373 Aligned: 56 Modelled: 57 Confidence: 81.2% Identity: 23% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: TrmB middle domain-like Phyre2 PDB 2f5t chain X Region: 317 - 373 Aligned: 56 Modelled: 57 Confidence: 75.7% Identity: 23% PDB header:transcription Chain: X: PDB Molecule:archaeal transcriptional regulator trmb; PDBTitle: crystal structure of the sugar binding domain of the archaeal2 transcriptional regulator trmb Phyre2 PDB 3mk7 chain F Region: 1 - 58 Aligned: 58 Modelled: 58 Confidence: 69.0% Identity: 19% PDB header:oxidoreductase Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p; PDBTitle: the structure of cbb3 cytochrome oxidase Phyre2 1 c3hsiC_ 2 c1v0sA_ 3 c1xdoB_ 4 d1v0wa1 5 d1xdpa3 6 d1byra_ 7 c2o8rA_ 8 d1v0wa2 9 d2o8ra3 10 d1xdpa4 11 d2o8ra4 12 c1q32C_ 13 c2c1lA_ 14 c3sq3C_ 15 d1jy1a2 16 c1nopB_ 17 d1q32a2 18 d2f5tx2 19 c2f5tX_ 20 c3mk7F_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3hsiC_ 100.0 15 PDB header:transferase Chain: C: PDB Molecule:phosphatidylserine synthase; PDBTitle: crystal structure of phosphatidylserine synthase haemophilus2 influenzae rd kw20 2 c1v0sA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:phospholipase d; PDBTitle: uninhibited form of phospholipase d from streptomyces sp.2 strain pmf 3 c1xdoB_ 100.0 14 PDB header:transferase Chain: B: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of escherichia coli polyphosphate kinase 4 d1v0wa1 100.0 15 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Phospholipase D 5 d1xdpa3 99.9 19 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 6 d1byra_ 99.9 23 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Nuclease 7 c2o8rA_ 99.9 15 PDB header:transferase Chain: A: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of polyphosphate kinase from2 porphyromonas gingivalis 8 d1v0wa2 99.9 23 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Phospholipase D 9 d2o8ra3 99.1 22 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 10 d1xdpa4 99.1 15 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 11 d2o8ra4 98.9 11 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 12 c1q32C_ 97.7 13 PDB header:replication,transcription,hydrolase Chain: C: PDB Molecule:tyrosyl-dna phosphodiesterase; PDBTitle: crystal structure analysis of the yeast tyrosyl-dna2 phosphodiesterase 13 c2c1lA_ 97.6 25 PDB header:hydrolase Chain: A: PDB Molecule:restriction endonuclease; PDBTitle: structure of the bfii restriction endonuclease 14 c3sq3C_ 97.2 15 PDB header:hydrolase Chain: C: PDB Molecule:tyrosyl-dna phosphodiesterase 1; PDBTitle: crystal structure analysis of the yeast tyrosyl-dna phosphodiesterase2 h182a mutant 15 d1jy1a2 95.3 18 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Tyrosyl-DNA phosphodiesterase TDP1 16 c1nopB_ 95.1 23 PDB header:hydrolase/dna Chain: B: PDB Molecule:tyrosyl-dna phosphodiesterase 1; PDBTitle: crystal structure of human tyrosyl-dna phosphodiesterase2 (tdp1) in complex with vanadate, dna and a human3 topoisomerase i-derived peptide 17 d1q32a2 94.6 23 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Tyrosyl-DNA phosphodiesterase TDP1 18 d2f5tx2 81.2 23 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:TrmB middle domain-like 19 c2f5tX_ 75.7 23 PDB header:transcription Chain: X: PDB Molecule:archaeal transcriptional regulator trmb; PDBTitle: crystal structure of the sugar binding domain of the archaeal2 transcriptional regulator trmb 20 c3mk7F_ 69.0 19 PDB header:oxidoreductase Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p; PDBTitle: the structure of cbb3 cytochrome oxidase 21 d1qzqa1 not modelled 66.2 36 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Tyrosyl-DNA phosphodiesterase TDP1 22 d1o98a1 not modelled 65.2 10 Fold:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Superfamily:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain 23 d1q32a1 not modelled 63.4 13 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Tyrosyl-DNA phosphodiesterase TDP1 24 d1jy1a1 not modelled 61.2 8 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Tyrosyl-DNA phosphodiesterase TDP1 25 c2a5hC_ not modelled 56.7 18 PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). 26 c2l82A_ not modelled 56.5 12 PDB header:de novo protein Chain: A: PDB Molecule:designed protein or32; PDBTitle: solution nmr structure of de novo designed protein, p-loop ntpase2 fold, northeast structural genomics consortium target or32 27 d1tfra2 not modelled 55.7 10 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 28 c3kgkA_ not modelled 54.1 11 PDB header:chaperone Chain: A: PDB Molecule:arsenical resistance operon trans-acting repressor arsd; PDBTitle: crystal structure of arsd 29 c2b34C_ not modelled 45.3 19 PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans 30 c1o98A_ not modelled 39.9 10 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate 31 d1yaca_ not modelled 36.5 21 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 32 c3ktbD_ not modelled 35.9 15 PDB header:transcription regulator Chain: D: PDB Molecule:arsenical resistance operon trans-acting repressor; PDBTitle: crystal structure of arsenical resistance operon trans-acting2 repressor from bacteroides vulgatus atcc 8482 33 c2yv5A_ not modelled 35.9 17 PDB header:hydrolase Chain: A: PDB Molecule:yjeq protein; PDBTitle: crystal structure of yjeq from aquifex aeolicus 34 d2r6gf1 not modelled 34.2 18 Fold:MalF N-terminal region-like Superfamily:MalF N-terminal region-like Family:MalF N-terminal region-like 35 c3gbcA_ not modelled 27.9 26 PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide 36 d1x9ga_ not modelled 27.6 14 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 37 c2nytB_ not modelled 27.0 12 PDB header:hydrolase Chain: B: PDB Molecule:probable c->u-editing enzyme apobec-2; PDBTitle: the apobec2 crystal structure and functional implications2 for aid 38 d1un8a4 not modelled 26.9 13 Fold:DAK1/DegV-like Superfamily:DAK1/DegV-like Family:DAK1 39 d1gz0a2 not modelled 24.7 15 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:RNA 2'-O ribose methyltransferase substrate binding domain 40 c1yzvA_ not modelled 23.3 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: hypothetical protein from trypanosoma cruzi 41 d1im5a_ not modelled 22.7 16 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 42 d1fftb2 not modelled 20.5 17 Fold:Transmembrane helix hairpin Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region Family:Cytochrome c oxidase subunit II-like, transmembrane region 43 c1pt9B_ not modelled 20.1 16 PDB header:oxidoreductase Chain: B: PDB Molecule:nad(p) transhydrogenase, mitochondrial; PDBTitle: crystal structure analysis of the diii component of transhydrogenase2 with a thio-nicotinamide nucleotide analogue 44 c2r60A_ not modelled 20.0 33 PDB header:transferase Chain: A: PDB Molecule:glycosyl transferase, group 1; PDBTitle: structure of apo sucrose phosphate synthase (sps) of2 halothermothrix orenii 45 c2bruC_ not modelled 20.0 16 PDB header:oxidoreductase Chain: C: PDB Molecule:nad(p) transhydrogenase subunit beta; PDBTitle: complex of the domain i and domain iii of escherichia coli2 transhydrogenase 46 c3l2iB_ not modelled 19.8 13 PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.85 angstrom crystal structure of the 3-dehydroquinate dehydratase2 (arod) from salmonella typhimurium lt2. 47 d1d4oa_ not modelled 19.5 16 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Transhydrogenase domain III (dIII) 48 d1pnoa_ not modelled 19.4 10 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Transhydrogenase domain III (dIII) 49 d1ueha_ not modelled 17.9 16 Fold:Undecaprenyl diphosphate synthase Superfamily:Undecaprenyl diphosphate synthase Family:Undecaprenyl diphosphate synthase 50 d1gz0f2 not modelled 17.8 15 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:RNA 2'-O ribose methyltransferase substrate binding domain 51 c2x7mA_ not modelled 17.1 5 PDB header:hydrolase Chain: A: PDB Molecule:archaemetzincin; PDBTitle: crystal structure of archaemetzincin (amza) from methanopyrus2 kandleri at 1.5 a resolution 52 c2q5cA_ not modelled 16.6 9 PDB header:transcription Chain: A: PDB Molecule:ntrc family transcriptional regulator; PDBTitle: crystal structure of ntrc family transcriptional regulator from2 clostridium acetobutylicum 53 c2b8eB_ not modelled 16.4 13 PDB header:membrane protein Chain: B: PDB Molecule:cation-transporting atpase; PDBTitle: copa atp binding domain 54 c3dy0B_ not modelled 16.0 40 PDB header:blood clotting, hydrolase inhibitor Chain: B: PDB Molecule:c-terminus plasma serine protease inhibitor; PDBTitle: crystal structure of cleaved pci bound to heparin 55 c2h0rD_ not modelled 15.5 17 PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p 56 c1lq8H_ not modelled 14.9 40 PDB header:blood clotting Chain: H: PDB Molecule:plasma serine protease inhibitor; PDBTitle: crystal structure of cleaved protein c inhibitor 57 c2pjuD_ not modelled 14.9 14 PDB header:transcription Chain: D: PDB Molecule:propionate catabolism operon regulatory protein; PDBTitle: crystal structure of propionate catabolism operon2 regulatory protein prpr 58 c1s21A_ not modelled 14.5 23 PDB header:chaperone Chain: A: PDB Molecule:orf2; PDBTitle: crystal structure of avrpphf orf2, a type iii effector from2 p. syringae 59 d1s21a_ not modelled 14.5 23 Fold:ADP-ribosylation Superfamily:ADP-ribosylation Family:AvrPphF ORF2, a type III effector 60 c1t3gB_ not modelled 13.9 11 PDB header:membrane protein Chain: B: PDB Molecule:x-linked interleukin-1 receptor accessory PDBTitle: crystal structure of the toll/interleukin-1 receptor (tir)2 domain of human il-1rapl 61 d1ay7b_ not modelled 13.9 12 Fold:Barstar-like Superfamily:Barstar-related Family:Barstar-related 62 c2wtaA_ not modelled 13.8 14 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: acinetobacter baumanii nicotinamidase pyrazinamidease 63 c2yvkA_ not modelled 13.8 11 PDB header:isomerase Chain: A: PDB Molecule:methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of 5-methylthioribose 1-phosphate2 isomerase product complex from bacillus subtilis 64 c3hu5B_ not modelled 13.7 14 PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough 65 d1x94a_ not modelled 13.6 15 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 66 d1pjqa2 not modelled 13.6 13 Fold:Tetrapyrrole methylase Superfamily:Tetrapyrrole methylase Family:Tetrapyrrole methylase 67 d1o57a2 not modelled 13.5 14 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 68 d1t5oa_ not modelled 13.4 13 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 69 c3js3C_ not modelled 13.4 8 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of type i 3-dehydroquinate dehydratase (arod) from2 clostridium difficile with covalent reaction intermediate 70 c2rddB_ not modelled 13.4 17 PDB header:membrane protein/transport protein Chain: B: PDB Molecule:upf0092 membrane protein yajc; PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix. 71 d1nvmb1 not modelled 13.4 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 72 d3dtub2 not modelled 13.3 7 Fold:Transmembrane helix hairpin Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region Family:Cytochrome c oxidase subunit II-like, transmembrane region 73 c3igzB_ not modelled 13.2 9 PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration 74 c2iksA_ not modelled 13.0 8 PDB header:transcription Chain: A: PDB Molecule:dna-binding transcriptional dual regulator; PDBTitle: crystal structure of n-terminal truncated dna-binding transcriptional2 dual regulator from escherichia coli k12 75 d2fcja1 not modelled 12.9 7 Fold:Toprim domain Superfamily:Toprim domain Family:Toprim domain 76 d1t9ka_ not modelled 12.7 20 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 77 d1s4da_ not modelled 12.6 10 Fold:Tetrapyrrole methylase Superfamily:Tetrapyrrole methylase Family:Tetrapyrrole methylase 78 c3r2jC_ not modelled 12.5 15 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate 79 c2hqbA_ not modelled 12.2 8 PDB header:transcription Chain: A: PDB Molecule:transcriptional activator of comk gene; PDBTitle: crystal structure of a transcriptional activator of comk2 gene from bacillus halodurans 80 c2voyC_ not modelled 12.2 38 PDB header:hydrolase Chain: C: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus 81 c3brqA_ not modelled 12.0 5 PDB header:transcription regulator Chain: A: PDB Molecule:hth-type transcriptional regulator ascg; PDBTitle: crystal structure of the escherichia coli transcriptional repressor2 ascg 82 c3zvmA_ not modelled 11.9 20 PDB header:hydrolase/transferase/dna Chain: A: PDB Molecule:bifunctional polynucleotide phosphatase/kinase; PDBTitle: the structural basis for substrate recognition by mammalian2 polynucleotide kinase 3' phosphatase 83 c1hf2A_ not modelled 11.8 14 PDB header:cell division protein Chain: A: PDB Molecule:septum site-determining protein minc; PDBTitle: crystal structure of the bacterial cell-division inhibitor2 minc from t. maritima 84 c3a11D_ not modelled 11.7 10 PDB header:isomerase Chain: D: PDB Molecule:translation initiation factor eif-2b, delta PDBTitle: crystal structure of ribose-1,5-bisphosphate isomerase from2 thermococcus kodakaraensis kod1 85 c3h75A_ not modelled 11.6 7 PDB header:sugar binding protein Chain: A: PDB Molecule:periplasmic sugar-binding domain protein; PDBTitle: crystal structure of a periplasmic sugar-binding protein from the2 pseudomonas fluorescens 86 d1acoa2 not modelled 11.5 10 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 87 d1gpja3 not modelled 11.4 15 Fold:Ferredoxin-like Superfamily:Glutamyl tRNA-reductase catalytic, N-terminal domain Family:Glutamyl tRNA-reductase catalytic, N-terminal domain 88 d1nr3a_ not modelled 11.4 21 Fold:DNA-binding protein Tfx Superfamily:DNA-binding protein Tfx Family:DNA-binding protein Tfx 89 c2rchA_ not modelled 11.3 19 PDB header:lyase Chain: A: PDB Molecule:cytochrome p450 74a; PDBTitle: crystal structure of arabidopsis thaliana allene oxide synthase (aos,2 cytochrome p450 74a, cyp74a) complexed with 13(s)-hod at 1.85 a3 resolution 90 d1ecfa1 not modelled 11.0 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 91 c3ny7A_ not modelled 10.9 13 PDB header:membrane protein Chain: A: PDB Molecule:sulfate transporter; PDBTitle: stas domain of ychm bound to acp 92 d1j5pa4 not modelled 10.7 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 93 c3h5oB_ not modelled 10.7 15 PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator gntr; PDBTitle: the crystal structure of transcription regulator gntr from2 chromobacterium violaceum 94 c3ecsD_ not modelled 10.5 13 PDB header:translation Chain: D: PDB Molecule:translation initiation factor eif-2b subunit PDBTitle: crystal structure of human eif2b alpha 95 c3bblA_ not modelled 10.4 11 PDB header:regulatory protein Chain: A: PDB Molecule:regulatory protein of laci family; PDBTitle: crystal structure of a regulatory protein of laci family from2 chloroflexus aggregans 96 d1qyda_ not modelled 10.2 6 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 97 d1gqna_ not modelled 10.0 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 98 c1o57A_ not modelled 10.0 14 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 99 d1wdea_ not modelled 10.0 14 Fold:Tetrapyrrole methylase Superfamily:Tetrapyrrole methylase Family:Tetrapyrrole methylase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0