Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	C	G	I	V	G	I	A	G	V	M	P	V	N	Q	S	I	Y	D	A	L	T	V	L	Q	H	R	G	Q	D	A	A	G	I	I	T	I	D	A	N	N	C	F	R	L	R	K	A	N	G	L	V	S	D	V	F	E	A	R	H
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	Q	R	L	Q	G	N	M	G	I	G	H	V	R	Y	P	T	A	G	S	S	S	A	S	E	A	Q	P	F	Y	V	N	S	P	Y	G	I	T	L	A	H	N	G	N	L	T	N	A	H	E	L	R	K	K	L	F	E	E	K	R
Secondary structure
SS confidence
Disorder		?			?																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	H	I	N	T	T	S	D	S	E	I	L	L	N	I	F	A	S	E	L	D	N	F	R	H	Y	P	L	E	A	D	N	I	F	A	A	I	A	A	T	N	R	L	I	R	G	A	Y	A	C	V	A	M	I	I	G	H	G	M	V
Secondary structure
SS confidence
Disorder																										?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	F	R	D	P	N	G	I	R	P	L	V	L	G	K	R	D	I	D	E	N	R	T	E	Y	M	V	A	S	E	S	V	A	L	D	T	L	G	F	D	F	L	R	D	V	A	P	G	E	A	I	Y	I	T	E	E	G	Q	L	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	R	Q	C	A	D	N	P	V	S	N	P	C	L	F	E	Y	V	Y	F	A	R	P	D	S	F	I	D	K	I	S	V	Y	S	A	R	V	N	M	G	T	K	L	G	E	K	I	A	R	E	W	E	D	L	D	I	D	V	V	I
Secondary structure
SS confidence
Disorder							?	?	?	?																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		P	I	P	E	T	S	C	D	I	A	L	E	I	A	R	I	L	G	K	P	Y	R	Q	G	F	V	K	N	R	Y	V	G	R	T	F	I	M	P	G	Q	Q	L	R	R	K	S	V	R	R	K	L	N	A	N	R	A	E	F	R	D
Secondary structure
SS confidence
Disorder																																						?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		K	N	V	L	L	V	D	D	S	I	V	R	G	T	T	S	E	Q	I	I	E	M	A	R	E	A	G	A	K	K	V	Y	L	A	S	A	A	P	E	I	R	F	P	N	V	Y	G	I	D	M	P	S	A	T	E	L	I	A	H	G
Secondary structure
SS confidence
Disorder										?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		R	E	V	D	E	I	R	Q	I	I	G	A	D	G	L	I	F	Q	D	L	N	D	L	I	D	A	V	R	A	E	N	P	D	I	Q	Q	F	E	C	S	V	F	N	G	V	Y	V	T	K	D	V	D	Q	G	Y	L	D	F	L	D
Secondary structure
SS confidence
Disorder																													?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.
Sequence		T	L	R	N	D	D	A	K	A	V	Q	R	Q	N	E	V	E	N	L	E	M	H	N	E	G
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1ecj chain B Region: 2 - 493 Aligned: 492 Modelled: 492 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer Phyre2 PDB 1gph chain 1 Region: 2 - 483 Aligned: 459 Modelled: 482 Confidence: 100.0% Identity: 41% PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis Phyre2 PDB 1ecf chain A domain 1 Region: 251 - 493 Aligned: 243 Modelled: 243 Confidence: 100.0% Identity: 100% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1gph chain 1 domain 1 Region: 252 - 483 Aligned: 227 Modelled: 232 Confidence: 100.0% Identity: 45% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1ecf chain A domain 2 Region: 2 - 248 Aligned: 247 Modelled: 247 Confidence: 100.0% Identity: 100% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1gph chain 1 domain 2 Region: 2 - 251 Aligned: 232 Modelled: 250 Confidence: 100.0% Identity: 38% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1jxa chain A Region: 2 - 253 Aligned: 231 Modelled: 242 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:glucosamine 6-phosphate synthase; PDBTitle: glucosamine 6-phosphate synthase with glucose 6-phosphate Phyre2 PDB 1xff chain A Region: 2 - 252 Aligned: 230 Modelled: 238 Confidence: 100.0% Identity: 29% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1ofd chain A domain 3 Region: 2 - 240 Aligned: 226 Modelled: 232 Confidence: 100.0% Identity: 27% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1ea0 chain A domain 3 Region: 2 - 240 Aligned: 227 Modelled: 238 Confidence: 100.0% Identity: 32% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1ct9 chain D Region: 2 - 322 Aligned: 244 Modelled: 263 Confidence: 100.0% Identity: 25% PDB header:ligase Chain: D: PDB Molecule:asparagine synthetase b; PDBTitle: crystal structure of asparagine synthetase b from2 escherichia coli Phyre2 PDB 1ct9 chain A domain 2 Region: 2 - 243 Aligned: 186 Modelled: 197 Confidence: 100.0% Identity: 28% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1te5 chain A Region: 2 - 242 Aligned: 228 Modelled: 235 Confidence: 100.0% Identity: 22% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 3mdn chain D Region: 2 - 246 Aligned: 212 Modelled: 244 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: D: PDB Molecule:glutamine aminotransferase class-ii domain protein; PDBTitle: structure of glutamine aminotransferase class-ii domain protein2 (spo2029) from silicibacter pomeroyi Phyre2 PDB 1m1z chain B Region: 24 - 322 Aligned: 227 Modelled: 263 Confidence: 99.9% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:beta-lactam synthetase; PDBTitle: beta-lactam synthetase apo enzyme Phyre2 PDB 1q15 chain A Region: 23 - 312 Aligned: 212 Modelled: 233 Confidence: 99.9% Identity: 15% PDB header:biosynthetic protein Chain: A: PDB Molecule:cara; PDBTitle: carbapenam synthetase Phyre2 PDB 1jgt chain A domain 2 Region: 29 - 246 Aligned: 183 Modelled: 196 Confidence: 99.9% Identity: 20% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1q15 chain A domain 2 Region: 22 - 238 Aligned: 155 Modelled: 168 Confidence: 99.9% Identity: 16% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 2vdc chain F Region: 15 - 239 Aligned: 213 Modelled: 225 Confidence: 99.9% Identity: 21% PDB header:oxidoreductase Chain: F: PDB Molecule:glutamate synthase [nadph] large chain; PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications. Phyre2 PDB 1lm1 chain A Region: 15 - 234 Aligned: 206 Modelled: 219 Confidence: 99.9% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:ferredoxin-dependent glutamate synthase; PDBTitle: structural studies on the synchronization of catalytic centers in2 glutamate synthase: native enzyme Phyre2 1 c1ecjB_ 2 c1gph1_ 3 d1ecfa1 4 d1gph11 5 d1ecfa2 6 d1gph12 7 c1jxaA_ 8 d1xffa_ 9 d1ofda3 10 d1ea0a3 11 c1ct9D_ 12 d1ct9a2 13 d1te5a_ 14 c3mdnD_ 15 c1m1zB_ 16 c1q15A_ 17 d1jgta2 18 d1q15a2 19 c2vdcF_ 20 c1lm1A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499