Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	I	L	H	T	S	D	W	H	L	G	Q	N	F	Y	S	K	S	R	E	A	E	H	Q	A	F	L	D	W	L	L	E	T	A	Q	T	H	Q	V	D	A	I	I	V	A	G	D	V	F	D	T	G	S	P	P	S	Y	A	R
Secondary structure
SS confidence
Disorder		?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	L	Y	N	R	F	V	V	N	L	Q	Q	T	G	C	H	L	V	V	L	A	G	N	H	D	S	V	A	T	L	N	E	S	R	D	I	M	A	F	L	N	T	T	V	V	A	S	A	G	H	A	P	Q	I	L	P	R	R	D	G
Secondary structure
SS confidence
Disorder																													?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	P	G	A	V	L	C	P	I	P	F	L	R	P	R	D	I	I	T	S	Q	A	G	L	N	G	I	E	K	Q	Q	H	L	L	A	A	I	T	D	Y	Y	Q	Q	H	Y	A	D	A	C	K	L	R	G	D	Q	P	L	P	I	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	T	G	H	L	T	T	V	G	A	S	K	S	D	A	V	R	D	I	Y	I	G	T	L	D	A	F	P	A	Q	N	F	P	P	A	D	Y	I	A	L	G	H	I	H	R	A	Q	I	I	G	G	M	E	H	V	R	Y	C	G	S
Secondary structure
SS confidence
Disorder											?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	I	P	L	S	F	D	E	C	G	K	S	K	Y	V	H	L	V	T	F	S	N	G	K	L	E	S	V	E	N	L	N	V	P	V	T	Q	P	M	A	V	L	K	G	D	L	A	S	I	T	A	Q	L	E	Q	W	R	D	V	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Q	E	P	P	V	W	L	D	I	E	I	T	T	D	E	Y	L	H	D	I	Q	R	K	I	Q	A	L	T	E	S	L	P	V	E	V	L	L	V	R	R	S	R	E	Q	R	E	R	V	L	A	S	Q	Q	R	E	T	L	S	E	L
Secondary structure
SS confidence
Disorder																																												?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400
Sequence		S	V	E	E	V	F	N	R	R	L	A	L	E	E	L	D	E	S	Q	Q	Q	R	L	Q	H	L	F	T	T	T	L	H	T	L	A	G	E	H	E	A
Secondary structure
SS confidence
Disorder													?	?	?	?	?																				?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3qg5 chain D Region: 1 - 398 Aligned: 361 Modelled: 397 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: D: PDB Molecule:mre11; PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair Phyre2 PDB 3t1i chain C Region: 1 - 333 Aligned: 303 Modelled: 314 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: C: PDB Molecule:double-strand break repair protein mre11a; PDBTitle: crystal structure of human mre11: understanding tumorigenic mutations Phyre2 PDB 2q8u chain A Region: 1 - 317 Aligned: 276 Modelled: 297 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:exonuclease, putative; PDBTitle: crystal structure of mre11 from thermotoga maritima msb8 (tm1635) at2 2.20 a resolution Phyre2 PDB 3av0 chain A Region: 1 - 389 Aligned: 340 Modelled: 361 Confidence: 100.0% Identity: 19% PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11-rad50 bound to atp s Phyre2 PDB 3auz chain A Region: 1 - 310 Aligned: 273 Modelled: 293 Confidence: 100.0% Identity: 21% PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11 with manganese Phyre2 PDB 1ii7 chain A Region: 1 - 340 Aligned: 307 Modelled: 310 Confidence: 100.0% Identity: 18% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: DNA double-strand break repair nuclease Phyre2 PDB 3ib7 chain A Region: 2 - 279 Aligned: 245 Modelled: 258 Confidence: 99.9% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:icc protein; PDBTitle: crystal structure of full length rv0805 Phyre2 PDB 2yvt chain A domain 1 Region: 2 - 272 Aligned: 231 Modelled: 241 Confidence: 99.9% Identity: 13% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: TT1561-like Phyre2 PDB 3d03 chain A domain 1 Region: 1 - 270 Aligned: 240 Modelled: 252 Confidence: 99.9% Identity: 16% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: GpdQ-like Phyre2 PDB 2xmo chain B Region: 2 - 274 Aligned: 261 Modelled: 273 Confidence: 99.9% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 Phyre2 PDB 1ush chain A domain 2 Region: 2 - 264 Aligned: 246 Modelled: 259 Confidence: 99.9% Identity: 15% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain Phyre2 PDB 1uf3 chain A Region: 2 - 271 Aligned: 221 Modelled: 247 Confidence: 99.9% Identity: 14% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: TT1561-like Phyre2 PDB 3qfn chain A Region: 1 - 274 Aligned: 213 Modelled: 222 Confidence: 99.8% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of streptococcal asymmetric ap4a hydrolase and2 phosphodiesterase spr1479/saph in complex with inorganic phosphate Phyre2 PDB 1ute chain A Region: 1 - 285 Aligned: 272 Modelled: 285 Confidence: 99.8% Identity: 14% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: Purple acid phosphatase-like Phyre2 PDB 1qhw chain A Region: 1 - 274 Aligned: 262 Modelled: 274 Confidence: 99.8% Identity: 14% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: Purple acid phosphatase-like Phyre2 PDB 1qhw chain A Region: 1 - 274 Aligned: 262 Modelled: 274 Confidence: 99.8% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:protein (purple acid phosphatase); PDBTitle: purple acid phosphatase from rat bone Phyre2 PDB 1s3l chain A Region: 1 - 269 Aligned: 163 Modelled: 180 Confidence: 99.8% Identity: 18% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: YfcE-like Phyre2 PDB 1s3m chain A Region: 1 - 269 Aligned: 163 Modelled: 180 Confidence: 99.8% Identity: 18% PDB header:phosphodiesterase Chain: A: PDB Molecule:hypothetical protein mj0936; PDBTitle: structural and functional characterization of a novel2 archaeal phosphodiesterase Phyre2 PDB 2nxf chain A domain 1 Region: 2 - 279 Aligned: 274 Modelled: 278 Confidence: 99.8% Identity: 9% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: ADPRibase-Mn-like Phyre2 PDB 2hy1 chain A Region: 1 - 272 Aligned: 220 Modelled: 243 Confidence: 99.7% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:rv0805; PDBTitle: crystal structure of rv0805 Phyre2 1 c3qg5D_ 2 c3t1iC_ 3 c2q8uA_ 4 c3av0A_ 5 c3auzA_ 6 d1ii7a_ 7 c3ib7A_ 8 d2yvta1 9 d3d03a1 10 c2xmoB_ 11 d1usha2 12 d1uf3a_ 13 c3qfnA_ 14 d1utea_ 15 d1qhwa_ 16 c1qhwA_ 17 d1s3la_ 18 c1s3mA_ 19 d2nxfa1 20 c2hy1A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3qg5D_ 100.0 21 PDB header:hydrolase Chain: D: PDB Molecule:mre11; PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair 2 c3t1iC_ 100.0 17 PDB header:hydrolase Chain: C: PDB Molecule:double-strand break repair protein mre11a; PDBTitle: crystal structure of human mre11: understanding tumorigenic mutations 3 c2q8uA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:exonuclease, putative; PDBTitle: crystal structure of mre11 from thermotoga maritima msb8 (tm1635) at2 2.20 a resolution 4 c3av0A_ 100.0 19 PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11-rad50 bound to atp s 5 c3auzA_ 100.0 21 PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11 with manganese 6 d1ii7a_ 100.0 18 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DNA double-strand break repair nuclease 7 c3ib7A_ 99.9 21 PDB header:hydrolase Chain: A: PDB Molecule:icc protein; PDBTitle: crystal structure of full length rv0805 8 d2yvta1 99.9 13 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like 9 d3d03a1 99.9 16 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:GpdQ-like 10 c2xmoB_ 99.9 14 PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 11 d1usha2 99.9 15 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 12 d1uf3a_ 99.9 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like 13 c3qfnA_ 99.8 21 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of streptococcal asymmetric ap4a hydrolase and2 phosphodiesterase spr1479/saph in complex with inorganic phosphate 14 d1utea_ 99.8 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 15 d1qhwa_ 99.8 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 16 c1qhwA_ 99.8 14 PDB header:hydrolase Chain: A: PDB Molecule:protein (purple acid phosphatase); PDBTitle: purple acid phosphatase from rat bone 17 d1s3la_ 99.8 18 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 18 c1s3mA_ 99.8 18 PDB header:phosphodiesterase Chain: A: PDB Molecule:hypothetical protein mj0936; PDBTitle: structural and functional characterization of a novel2 archaeal phosphodiesterase 19 d2nxfa1 99.8 9 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:ADPRibase-Mn-like 20 c2hy1A_ 99.7 22 PDB header:hydrolase Chain: A: PDB Molecule:rv0805; PDBTitle: crystal structure of rv0805 21 d2hy1a1 not modelled 99.7 22 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:GpdQ-like 22 d1su1a_ not modelled 99.7 21 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 23 c1su1A_ not modelled 99.7 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein yfce; PDBTitle: structural and biochemical characterization of yfce, a2 phosphoesterase from e. coli 24 c1oidA_ not modelled 99.6 16 PDB header:hydrolase Chain: A: PDB Molecule:protein usha; PDBTitle: 5'-nucleotidase (e. coli) with an engineered disulfide2 bridge (s228c, p513c) 25 d1nnwa_ not modelled 99.6 10 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Phosphoesterase-related 26 d1z2wa1 not modelled 99.6 16 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 27 d2a22a1 not modelled 99.6 19 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 28 d2z1aa2 not modelled 99.6 18 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 29 c3rqzC_ not modelled 99.5 19 PDB header:hydrolase Chain: C: PDB Molecule:metallophosphoesterase; PDBTitle: crystal structure of metallophosphoesterase from sphaerobacter2 thermophilus 30 c3qfkA_ not modelled 99.5 15 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: 2.05 angstrom crystal structure of putative 5'-nucleotidase from2 staphylococcus aureus in complex with alpha-ketoglutarate 31 c3rl4A_ not modelled 99.4 17 PDB header:hydrolase Chain: A: PDB Molecule:metallophosphoesterase mpped2; PDBTitle: rat metallophosphodiesterase mpped2 g252h mutant 32 c2kknA_ not modelled 99.4 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of themotoga maritima protein tm1076:2 northeast structural genomics consortium target vt57 33 c2z1aA_ not modelled 99.4 18 PDB header:hydrolase Chain: A: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase precursor from thermus2 thermophilus hb8 34 c3ivdA_ not modelled 99.4 16 PDB header:hydrolase Chain: A: PDB Molecule:nucleotidase; PDBTitle: putative 5'-nucleotidase (c4898) from escherichia coli in2 complex with uridine 35 d1xzwa2 not modelled 99.4 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 36 c3gveB_ not modelled 99.4 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:yfkn protein; PDBTitle: crystal structure of calcineurin-like phosphoesterase yfkn from2 bacillus subtilis 37 d3ck2a1 not modelled 99.3 24 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 38 d1xm7a_ not modelled 99.3 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Hypothetical protein aq 1666 39 d2qfra2 not modelled 99.2 13 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 40 d3c9fa2 not modelled 99.2 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 41 c3jyfB_ not modelled 99.2 15 PDB header:hydrolase Chain: B: PDB Molecule:2',3'-cyclic nucleotide 2'-phosphodiesterase/3'- PDBTitle: the crystal structure of a 2,3-cyclic nucleotide 2-2 phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor3 protein from klebsiella pneumoniae subsp. pneumoniae mgh 78578 42 c3zu0A_ not modelled 99.2 15 PDB header:hydrolase Chain: A: PDB Molecule:nad nucleotidase; PDBTitle: structure of haemophilus influenzae nad nucleotidase (nadn) 43 c2wdfA_ not modelled 99.2 18 PDB header:hydrolase Chain: A: PDB Molecule:sulfur oxidation protein soxb; PDBTitle: termus thermophilus sulfate thiohydrolase soxb 44 c3c9fB_ not modelled 99.2 14 PDB header:hydrolase Chain: B: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase from candida albicans sc5314 45 c1kbpB_ not modelled 98.9 15 PDB header:hydrolase (phosphoric monoester) Chain: B: PDB Molecule:purple acid phosphatase; PDBTitle: kidney bean purple acid phosphatase 46 c1xzwB_ not modelled 98.8 13 PDB header:hydrolase Chain: B: PDB Molecule:purple acid phosphatase; PDBTitle: sweet potato purple acid phosphatase/phosphate complex 47 d1t70a_ not modelled 98.8 16 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DR1281-like 48 d1g5ba_ not modelled 98.8 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 49 d1t71a_ not modelled 98.6 16 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DR1281-like 50 d2z06a1 not modelled 98.5 15 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TTHA0625-like 51 c2zbmA_ not modelled 98.4 25 PDB header:hydrolase Chain: A: PDB Molecule:protein-tyrosine-phosphatase; PDBTitle: crystal structure of i115m mutant cold-active protein2 tyrosine phosphatase 52 c2qjcA_ not modelled 98.3 30 PDB header:hydrolase Chain: A: PDB Molecule:diadenosine tetraphosphatase, putative; PDBTitle: crystal structure of a putative diadenosine tetraphosphatase 53 c3e0jG_ not modelled 98.2 17 PDB header:transferase Chain: G: PDB Molecule:dna polymerase subunit delta-2; PDBTitle: x-ray structure of the complex of regulatory subunits of2 human dna polymerase delta 54 c2dfjA_ not modelled 98.1 28 PDB header:hydrolase Chain: A: PDB Molecule:diadenosinetetraphosphatase; PDBTitle: crystal structure of the diadenosine tetraphosphate2 hydrolase from shigella flexneri 2a 55 d1jk7a_ not modelled 97.6 23 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 56 d3c5wc1 not modelled 97.5 25 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 57 d1s70a_ not modelled 97.4 23 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 58 d1s95a_ not modelled 97.3 29 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 59 c2jogA_ not modelled 97.3 25 PDB header:hydrolase Chain: A: PDB Molecule:calmodulin-dependent calcineurin a subunit alpha PDBTitle: structure of the calcineurin-nfat complex 60 c3floG_ not modelled 97.2 14 PDB header:transferase Chain: G: PDB Molecule:dna polymerase alpha subunit b; PDBTitle: crystal structure of the carboxyl-terminal domain of yeast2 dna polymerase alpha in complex with its b subunit 61 c3icfB_ not modelled 97.2 24 PDB header:hydrolase Chain: B: PDB Molecule:serine/threonine-protein phosphatase t; PDBTitle: structure of protein serine/threonine phosphatase from saccharomyces2 cerevisiae with similarity to human phosphatase pp5 62 c1auiA_ not modelled 97.1 25 PDB header:hydrolase Chain: A: PDB Molecule:serine/threonine phosphatase 2b; PDBTitle: human calcineurin heterodimer 63 d1auia_ not modelled 97.1 25 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 64 c2p6bC_ not modelled 97.0 25 PDB header:hydrolase/hydrolase regulator Chain: C: PDB Molecule:calmodulin-dependent calcineurin a subunit alpha PDBTitle: crystal structure of human calcineurin in complex with2 pvivit peptide 65 d2p6ba1 not modelled 97.0 25 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 66 c1wao4_ not modelled 97.0 29 PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure 67 c3lmaC_ not modelled 90.0 16 PDB header:membrane protein Chain: C: PDB Molecule:stage v sporulation protein ad (spovad); PDBTitle: crystal structure of the stage v sporulation protein ad2 (spovad) from bacillus licheniformis. northeast structural3 genomics consortium target bir6. 68 c2ftpA_ not modelled 85.5 22 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 69 d2qeda1 not modelled 73.5 9 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Glyoxalase II (hydroxyacylglutathione hydrolase) 70 d2vgna3 not modelled 73.4 16 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:ERF1/Dom34 C-terminal domain-like 71 c2vgmA_ not modelled 71.3 16 PDB header:cell cycle Chain: A: PDB Molecule:dom34; PDBTitle: structure of yeast dom34 : a protein related to translation2 termination factor erf1 and involved in no-go decay. 72 d1mqoa_ not modelled 69.8 18 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 73 d1a9xb2 not modelled 67.3 13 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 74 d1b74a1 not modelled 65.9 19 Fold:ATC-like Superfamily:Aspartate/glutamate racemase Family:Aspartate/glutamate racemase 75 c3menC_ not modelled 65.7 14 PDB header:hydrolase Chain: C: PDB Molecule:acetylpolyamine aminohydrolase; PDBTitle: crystal structure of acetylpolyamine aminohydrolase from burkholderia2 pseudomallei, iodide soak 76 d1x52a1 not modelled 64.4 12 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:ERF1/Dom34 C-terminal domain-like 77 c3obwA_ not modelled 64.3 13 PDB header:hydrolase Chain: A: PDB Molecule:protein pelota homolog; PDBTitle: crystal structure of two archaeal pelotas reveal inter-domain2 structural plasticity 78 c3e96B_ not modelled 63.0 12 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii 79 c3s5oA_ not modelled 62.8 17 PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial; PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate 80 c3mcaB_ not modelled 62.3 13 PDB header:translation regulation/hydrolase Chain: B: PDB Molecule:protein dom34; PDBTitle: structure of the dom34-hbs1 complex and implications for its role in2 no-go decay 81 d3bzka5 not modelled 61.0 16 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Tex RuvX-like domain-like 82 c1keeH_ not modelled 58.6 19 PDB header:ligase Chain: H: PDB Molecule:carbamoyl-phosphate synthetase small chain; PDBTitle: inactivation of the amidotransferase activity of carbamoyl phosphate2 synthetase by the antibiotic acivicin 83 c3d0cB_ not modelled 57.9 15 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 oceanobacillus iheyensis at 1.9 a resolution 84 c2gcuD_ not modelled 57.5 17 PDB header:hydrolase Chain: D: PDB Molecule:putative hydroxyacylglutathione hydrolase 3; PDBTitle: x-ray structure of gene product from arabidopsis thaliana2 at1g53580 85 c3eb2A_ not modelled 57.4 12 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 86 c3b4uB_ not modelled 57.1 10 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58 87 c3bi8A_ not modelled 56.8 22 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of dihydrodipicolinate synthase from clostridium2 botulinum 88 d2g2ca1 not modelled 56.2 14 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 89 c3lciA_ not modelled 56.1 17 PDB header:lyase Chain: A: PDB Molecule:n-acetylneuraminate lyase; PDBTitle: the d-sialic acid aldolase mutant v251w 90 d1hl2a_ not modelled 55.9 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 91 c2rfgB_ not modelled 55.0 14 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from hahella2 chejuensis at 1.5a resolution 92 c2ohoA_ not modelled 55.0 20 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: structural basis for glutamate racemase inhibitor 93 d1a3xa2 not modelled 54.2 18 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 94 c1s1hB_ not modelled 53.9 17 PDB header:ribosome Chain: B: PDB Molecule:40s ribosomal protein s0-a; PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1h,4 contains 40s subunit. the 60s ribosomal subunit is in file5 1s1i. 95 c3qfeB_ not modelled 53.7 8 PDB header:lyase Chain: B: PDB Molecule:putative dihydrodipicolinate synthase family protein; PDBTitle: crystal structures of a putative dihydrodipicolinate synthase family2 protein from coccidioides immitis 96 d1e0ta2 not modelled 53.5 21 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 97 d2aama1 not modelled 52.9 17 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:TM1410-like 98 c2aamA_ not modelled 52.9 17 PDB header:hydrolase Chain: A: PDB Molecule:hypothetical protein tm1410; PDBTitle: crystal structure of a putative glycosidase (tm1410) from thermotoga2 maritima at 2.20 a resolution 99 c3qf7D_ not modelled 52.7 21 PDB header:hydrolase Chain: D: PDB Molecule:mre11; PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair 100 c1uz5A_ not modelled 52.1 25 PDB header:molybdopterin biosynthesis Chain: A: PDB Molecule:402aa long hypothetical molybdopterin PDBTitle: the crystal structure of molybdopterin biosynthesis moea2 protein from pyrococcus horikosii 101 d1jjta_ not modelled 51.4 13 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 102 d1xfka_ not modelled 50.9 21 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 103 d1znba_ not modelled 50.6 14 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 104 c3cprB_ not modelled 50.4 12 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 105 c3opyE_ not modelled 49.9 16 PDB header:transferase Chain: E: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 106 c3i4tA_ not modelled 49.7 38 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:diphthine synthase; PDBTitle: crystal structure of putative diphthine synthase from2 entamoeba histolytica 107 d1wdea_ not modelled 49.6 17 Fold:Tetrapyrrole methylase Superfamily:Tetrapyrrole methylase Family:Tetrapyrrole methylase 108 c3g0sA_ not modelled 49.4 12 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 109 c2zwrA_ not modelled 49.4 20 PDB header:hydrolase Chain: A: PDB Molecule:metallo-beta-lactamase superfamily protein; PDBTitle: crystal structure of ttha1623 from thermus thermophilus hb8 110 d2g50a2 not modelled 49.0 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 111 c3o8nA_ not modelled 48.9 8 PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase, muscle type; PDBTitle: structure of phosphofructokinase from rabbit skeletal muscle 112 c2r8wB_ not modelled 48.3 12 PDB header:lyase Chain: B: PDB Molecule:agr_c_1641p; PDBTitle: the crystal structure of dihydrodipicolinate synthase (atu0899) from2 agrobacterium tumefaciens str. c58 113 d1xm8a_ not modelled 47.7 15 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Glyoxalase II (hydroxyacylglutathione hydrolase) 114 c3opyH_ not modelled 47.0 15 PDB header:transferase Chain: H: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 115 c3opyB_ not modelled 47.0 15 PDB header:transferase Chain: B: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 116 c3h5dD_ not modelled 46.8 18 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from drug-resistant streptococcus2 pneumoniae 117 d2gm3a1 not modelled 46.8 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 118 c3u5cM_ not modelled 46.6 10 PDB header:ribosome Chain: M: PDB Molecule:40s ribosomal protein s12; PDBTitle: the structure of the eukaryotic ribosome at 3.0 a resolution 119 c3q9cF_ not modelled 46.6 20 PDB header:hydrolase Chain: F: PDB Molecule:acetylpolyamine amidohydrolase; PDBTitle: crystal structure of h159a apah complexed with n8-acetylspermidine 120 c3obyB_ not modelled 46.4 13 PDB header:hydrolase Chain: B: PDB Molecule:protein pelota homolog; PDBTitle: crystal structure of archaeoglobus fulgidus pelota reveals inter-2 domain structural plasticity

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0