Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	T	V	K	Q	I	E	A	A	K	P	K	E	K	P	Y	R	L	L	D	G	N	G	L	Y	L	Y	V	P	V	S	G	K	K	V	W	Q	L	R	Y	K	I	D	G	K	E	K	I	L	T	V	G	K	Y	P	L	M	T	L
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	E	A	R	D	K	A	W	T	A	R	K	D	I	S	V	G	I	D	P	V	K	A	K	K	A	S	S	N	N	N	S	F	S	A	I	Y	K	E	W	Y	E	H	K	K	Q	V	W	S	V	G	Y	A	T	E	L	A	K	M	F
Secondary structure
SS confidence
Disorder																	?		?	?										?																		?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	D	D	I	L	P	I	I	G	G	L	E	I	Q	D	I	E	P	M	Q	L	L	E	V	I	R	R	F	E	D	R	G	A	M	E	R	A	N	K	A	R	R	R	C	G	E	V	F	R	Y	A	I	V	T	G	R	A	K	Y	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		P	A	P	D	L	A	D	A	M	K	G	Y	R	K	K	N	F	P	F	L	P	A	D	Q	I	P	A	F	N	K	A	L	A	T	F	S	G	S	I	V	S	L	I	A	T	K	V	L	R	Y	T	A	L	R	T	K	E	L	R	S
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		M	L	W	K	N	V	D	F	E	N	R	I	I	T	I	D	A	S	V	M	K	G	R	K	I	H	V	V	P	M	S	D	Q	V	V	E	L	L	T	T	L	S	S	I	T	K	P	V	S	E	F	V	F	A	G	R	N	D	K	K
Secondary structure
SS confidence
Disorder																				?	?	?	?	?																							?												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		K	P	I	C	E	N	A	V	L	L	V	I	K	Q	I	G	Y	E	G	L	E	S	G	H	G	F	R	H	E	F	S	T	I	M	N	E	H	E	W	P	A	D	A	I	E	V	Q	L	A	H	A	N	G	G	S	V	R	G	I	Y
Secondary structure
SS confidence
Disorder		?	?	?																																															?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Sequence		N	H	A	Q	Y	L	D	K	R	R	E	M	M	Q	W	W	A	D	W	L	D	E	K	V	E
Secondary structure
SS confidence
Disorder																									?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1z1b chain A Region: 21 - 364 Aligned: 333 Modelled: 344 Confidence: 100.0% Identity: 16% PDB header:dna binding protein/dna Chain: A: PDB Molecule:integrase; PDBTitle: crystal structure of a lambda integrase dimer bound to a2 coc' core site Phyre2 PDB 1p7d chain A Region: 91 - 363 Aligned: 263 Modelled: 273 Confidence: 99.9% Identity: 13% Fold: DNA breaking-rejoining enzymes Superfamily: DNA breaking-rejoining enzymes Family: Lambda integrase-like, catalytic core Phyre2 PDB 1ma7 chain A Region: 92 - 378 Aligned: 285 Modelled: 287 Confidence: 99.9% Identity: 13% PDB header:hydrolase, ligase/dna Chain: A: PDB Molecule:cre recombinase; PDBTitle: crystal structure of cre site-specific recombinase2 complexed with a mutant dna substrate, loxp-a8/t27 Phyre2 PDB 2a3v chain A Region: 94 - 364 Aligned: 259 Modelled: 261 Confidence: 99.9% Identity: 15% PDB header:recombination Chain: A: PDB Molecule:site-specific recombinase inti4; PDBTitle: structural basis for broad dna-specificity in integron2 recombination Phyre2 PDB 1crx chain A Region: 94 - 378 Aligned: 283 Modelled: 285 Confidence: 99.9% Identity: 13% PDB header:replication/dna Chain: A: PDB Molecule:cre recombinase; PDBTitle: cre recombinase/dna complex reaction intermediate i Phyre2 PDB 3nkh chain B Region: 195 - 378 Aligned: 183 Modelled: 184 Confidence: 99.9% Identity: 16% PDB header:recombination Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of integrase from mrsa strain staphylococcus aureus Phyre2 PDB 1a0p chain A Region: 95 - 374 Aligned: 259 Modelled: 280 Confidence: 99.9% Identity: 14% PDB header:dna recombination Chain: A: PDB Molecule:site-specific recombinase xerd; PDBTitle: site-specific recombinase, xerd Phyre2 PDB 3ju0 chain A Region: 2 - 94 Aligned: 93 Modelled: 93 Confidence: 99.8% Identity: 37% PDB header:dna binding protein Chain: A: PDB Molecule:phage integrase; PDBTitle: structure of the arm-type binding domain of hai7 integrase Phyre2 PDB 3jtz chain A Region: 2 - 77 Aligned: 76 Modelled: 76 Confidence: 99.8% Identity: 38% PDB header:dna binding protein Chain: A: PDB Molecule:integrase; PDBTitle: structure of the arm-type binding domain of hpi integrase Phyre2 PDB 1aih chain A Region: 194 - 376 Aligned: 163 Modelled: 170 Confidence: 99.8% Identity: 15% Fold: DNA breaking-rejoining enzymes Superfamily: DNA breaking-rejoining enzymes Family: Lambda integrase-like, catalytic core Phyre2 PDB 1f44 chain A domain 2 Region: 193 - 378 Aligned: 184 Modelled: 186 Confidence: 99.7% Identity: 14% Fold: DNA breaking-rejoining enzymes Superfamily: DNA breaking-rejoining enzymes Family: Lambda integrase-like, catalytic core Phyre2 PDB 1a0p chain A domain 2 Region: 197 - 374 Aligned: 174 Modelled: 178 Confidence: 99.7% Identity: 15% Fold: DNA breaking-rejoining enzymes Superfamily: DNA breaking-rejoining enzymes Family: Lambda integrase-like, catalytic core Phyre2 PDB 1ae9 chain A Region: 197 - 364 Aligned: 164 Modelled: 168 Confidence: 99.7% Identity: 15% Fold: DNA breaking-rejoining enzymes Superfamily: DNA breaking-rejoining enzymes Family: Lambda integrase-like, catalytic core Phyre2 PDB 5crx chain B domain 2 Region: 193 - 349 Aligned: 157 Modelled: 157 Confidence: 99.4% Identity: 13% Fold: DNA breaking-rejoining enzymes Superfamily: DNA breaking-rejoining enzymes Family: Lambda integrase-like, catalytic core Phyre2 PDB 2kj8 chain A Region: 89 - 198 Aligned: 110 Modelled: 110 Confidence: 99.0% Identity: 98% PDB header:dna binding protein Chain: A: PDB Molecule:putative prophage cps-53 integrase; PDBTitle: nmr structure of fragment 87-196 from the putative phage2 integrase ints of e. coli: northeast structural genomics3 consortium target er652a, psi-2 Phyre2 PDB 2kj9 chain A Region: 82 - 195 Aligned: 113 Modelled: 114 Confidence: 99.0% Identity: 25% PDB header:dna binding protein Chain: A: PDB Molecule:integrase; PDBTitle: nmr structure of intb phage-integrase-like protein fragment2 90-199 from erwinia carotova subsp. atroseptica: northeast3 structural genomics consortium target ewr217e Phyre2 PDB 2kkv chain A Region: 86 - 203 Aligned: 117 Modelled: 118 Confidence: 99.0% Identity: 26% PDB header:dna binding protein Chain: A: PDB Molecule:integrase; PDBTitle: solution nmr structure of an integrase domain from protein2 spa4288 from salmonella enterica, northeast structural3 genomics consortium target slr105h Phyre2 PDB 2kiw chain A Region: 92 - 201 Aligned: 109 Modelled: 110 Confidence: 98.9% Identity: 13% PDB header:dna binding protein Chain: A: PDB Molecule:int protein; PDBTitle: solution nmr structure of the domain n-terminal to the2 integrase domain of sh1003 from staphylococcus3 haemolyticus. northeast structural genomics consortium4 target shr105f (64-166). Phyre2 PDB 2kd1 chain A Region: 87 - 200 Aligned: 114 Modelled: 114 Confidence: 98.8% Identity: 12% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dna integration/recombination/invertion protein; PDBTitle: solution nmr structure of the integrase-like domain from2 bacillus cereus ordered locus bc_1272. northeast3 structural genomics consortium target bcr268f Phyre2 PDB 2khq chain A Region: 91 - 195 Aligned: 104 Modelled: 105 Confidence: 98.7% Identity: 16% PDB header:dna binding protein Chain: A: PDB Molecule:integrase; PDBTitle: solution nmr structure of a phage integrase ssp19472 fragment 59-159 from staphylococcus saprophyticus,3 northeast structural genomics consortium target syr103b Phyre2 1 c1z1bA_ 2 d1p7da_ 3 c1ma7A_ 4 c2a3vA_ 5 c1crxA_ 6 c3nkhB_ 7 c1a0pA_ 8 c3ju0A_ 9 c3jtzA_ 10 d1aiha_ 11 d1f44a2 12 d1a0pa2 13 d1ae9a_ 14 d5crxb2 15 c2kj8A_ 16 c2kj9A_ 17 c2kkvA_ 18 c2kiwA_ 19 c2kd1A_ 20 c2khqA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1z1bA_ 100.0 16 PDB header:dna binding protein/dna Chain: A: PDB Molecule:integrase; PDBTitle: crystal structure of a lambda integrase dimer bound to a2 coc' core site 2 d1p7da_ 99.9 13 Fold:DNA breaking-rejoining enzymes Superfamily:DNA breaking-rejoining enzymes Family:Lambda integrase-like, catalytic core 3 c1ma7A_ 99.9 13 PDB header:hydrolase, ligase/dna Chain: A: PDB Molecule:cre recombinase; PDBTitle: crystal structure of cre site-specific recombinase2 complexed with a mutant dna substrate, loxp-a8/t27 4 c2a3vA_ 99.9 15 PDB header:recombination Chain: A: PDB Molecule:site-specific recombinase inti4; PDBTitle: structural basis for broad dna-specificity in integron2 recombination 5 c1crxA_ 99.9 13 PDB header:replication/dna Chain: A: PDB Molecule:cre recombinase; PDBTitle: cre recombinase/dna complex reaction intermediate i 6 c3nkhB_ 99.9 16 PDB header:recombination Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of integrase from mrsa strain staphylococcus aureus 7 c1a0pA_ 99.9 14 PDB header:dna recombination Chain: A: PDB Molecule:site-specific recombinase xerd; PDBTitle: site-specific recombinase, xerd 8 c3ju0A_ 99.8 37 PDB header:dna binding protein Chain: A: PDB Molecule:phage integrase; PDBTitle: structure of the arm-type binding domain of hai7 integrase 9 c3jtzA_ 99.8 38 PDB header:dna binding protein Chain: A: PDB Molecule:integrase; PDBTitle: structure of the arm-type binding domain of hpi integrase 10 d1aiha_ 99.8 15 Fold:DNA breaking-rejoining enzymes Superfamily:DNA breaking-rejoining enzymes Family:Lambda integrase-like, catalytic core 11 d1f44a2 99.7 14 Fold:DNA breaking-rejoining enzymes Superfamily:DNA breaking-rejoining enzymes Family:Lambda integrase-like, catalytic core 12 d1a0pa2 99.7 15 Fold:DNA breaking-rejoining enzymes Superfamily:DNA breaking-rejoining enzymes Family:Lambda integrase-like, catalytic core 13 d1ae9a_ 99.7 15 Fold:DNA breaking-rejoining enzymes Superfamily:DNA breaking-rejoining enzymes Family:Lambda integrase-like, catalytic core 14 d5crxb2 99.4 13 Fold:DNA breaking-rejoining enzymes Superfamily:DNA breaking-rejoining enzymes Family:Lambda integrase-like, catalytic core 15 c2kj8A_ 99.0 98 PDB header:dna binding protein Chain: A: PDB Molecule:putative prophage cps-53 integrase; PDBTitle: nmr structure of fragment 87-196 from the putative phage2 integrase ints of e. coli: northeast structural genomics3 consortium target er652a, psi-2 16 c2kj9A_ 99.0 25 PDB header:dna binding protein Chain: A: PDB Molecule:integrase; PDBTitle: nmr structure of intb phage-integrase-like protein fragment2 90-199 from erwinia carotova subsp. atroseptica: northeast3 structural genomics consortium target ewr217e 17 c2kkvA_ 99.0 26 PDB header:dna binding protein Chain: A: PDB Molecule:integrase; PDBTitle: solution nmr structure of an integrase domain from protein2 spa4288 from salmonella enterica, northeast structural3 genomics consortium target slr105h 18 c2kiwA_ 98.9 13 PDB header:dna binding protein Chain: A: PDB Molecule:int protein; PDBTitle: solution nmr structure of the domain n-terminal to the2 integrase domain of sh1003 from staphylococcus3 haemolyticus. northeast structural genomics consortium4 target shr105f (64-166). 19 c2kd1A_ 98.8 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dna integration/recombination/invertion protein; PDBTitle: solution nmr structure of the integrase-like domain from2 bacillus cereus ordered locus bc_1272. northeast3 structural genomics consortium target bcr268f 20 c2khqA_ 98.7 16 PDB header:dna binding protein Chain: A: PDB Molecule:integrase; PDBTitle: solution nmr structure of a phage integrase ssp19472 fragment 59-159 from staphylococcus saprophyticus,3 northeast structural genomics consortium target syr103b 21 c2oxoA_ not modelled 98.7 14 PDB header:dna binding protein Chain: A: PDB Molecule:integrase; PDBTitle: crystallization and structure determination of the core-2 binding domain of bacteriophage lambda integrase 22 c2khvA_ not modelled 98.7 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phage integrase; PDBTitle: solution nmr structure of protein nmul_a0922 from2 nitrosospira multiformis. northeast structural genomics3 consortium target nmr38b. 23 c2kj5A_ not modelled 98.7 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phage integrase; PDBTitle: solution nmr structure of a domain from a putative phage2 integrase protein nmul_a0064 from nitrosospira multiformis,3 northeast structural genomics consortium target nmr46c 24 c3lysC_ not modelled 98.7 14 PDB header:recombination Chain: C: PDB Molecule:prophage pi2 protein 01, integrase; PDBTitle: crystal structure of the n-terminal domain of the prophage2 pi2 protein 01 (integrase) from lactococcus lactis,3 northeast structural genomics consortium target kr124f 25 c2kkpA_ not modelled 98.6 11 PDB header:dna binding protein Chain: A: PDB Molecule:phage integrase; PDBTitle: solution nmr structure of the phage integrase sam-like2 domain from moth 1796 from moorella thermoacetica.3 northeast structural genomics consortium target mtr39k4 (residues 64-171). 26 c2kobA_ not modelled 98.6 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of clolep_01837 (fragment 61-160)2 from clostridium leptum. northeast structural genomics3 consortium target qlr8a 27 c2keyA_ not modelled 98.1 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative phage integrase; PDBTitle: solution nmr structure of a domain from a putative phage integrase2 protein bf2284 from bacteroides fragilis, northeast structural3 genomics consortium target bfr257c 28 c3nrwA_ not modelled 97.6 6 PDB header:recombination Chain: A: PDB Molecule:phage integrase/site-specific recombinase; PDBTitle: crystal structure of the n-terminal domain of phage integrase/site-2 specific recombinase (tnp) from haloarcula marismortui, northeast3 structural genomics consortium target hmr208a 29 c2v6eB_ not modelled 97.3 12 PDB header:hydrolase Chain: B: PDB Molecule:protelemorase; PDBTitle: protelomerase telk complexed with substrate dna 30 c2f4qA_ not modelled 93.9 14 PDB header:isomerase Chain: A: PDB Molecule:type i topoisomerase, putative; PDBTitle: crystal structure of deinococcus radiodurans topoisomerase ib 31 d1a0pa1 not modelled 93.7 9 Fold:SAM domain-like Superfamily:lambda integrase-like, N-terminal domain Family:lambda integrase-like, N-terminal domain 32 c3igmA_ not modelled 87.9 13 PDB header:transcription/dna Chain: A: PDB Molecule:pf14_0633 protein; PDBTitle: a 2.2a crystal structure of the ap2 domain of pf14_0633 from p.2 falciparum, bound as a domain-swapped dimer to its cognate dna 33 c2h7fX_ not modelled 82.6 16 PDB header:isomerase/dna Chain: X: PDB Molecule:dna topoisomerase 1; PDBTitle: structure of variola topoisomerase covalently bound to dna 34 d1gcca_ not modelled 75.9 18 Fold:DNA-binding domain Superfamily:DNA-binding domain Family:GCC-box binding domain 35 d1f44a1 not modelled 71.0 13 Fold:SAM domain-like Superfamily:lambda integrase-like, N-terminal domain Family:lambda integrase-like, N-terminal domain 36 c1kjkA_ not modelled 69.9 28 PDB header:viral protein Chain: A: PDB Molecule:integrase; PDBTitle: solution structure of the lambda integrase amino-terminal2 domain 37 d1z1ba1 not modelled 69.9 28 Fold:DNA-binding domain Superfamily:DNA-binding domain Family:lambda integrase N-terminal domain 38 d1qu6a2 not modelled 52.1 28 Fold:dsRBD-like Superfamily:dsRNA-binding domain-like Family:Double-stranded RNA-binding domain (dsRBD) 39 d1x48a1 not modelled 48.1 19 Fold:dsRBD-like Superfamily:dsRNA-binding domain-like Family:Double-stranded RNA-binding domain (dsRBD) 40 d1a41a_ not modelled 45.9 14 Fold:DNA breaking-rejoining enzymes Superfamily:DNA breaking-rejoining enzymes Family:Eukaryotic DNA topoisomerase I, catalytic core 41 d1q08a_ not modelled 33.3 17 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:DNA-binding N-terminal domain of transcription activators 42 d1r8da_ not modelled 28.6 18 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:DNA-binding N-terminal domain of transcription activators 43 c3d6zA_ not modelled 28.4 2 PDB header:transcription regulator/dna Chain: A: PDB Molecule:multidrug-efflux transporter 1 regulator; PDBTitle: crystal structure of r275e mutant of bmrr bound to dna and rhodamine 44 d2gf5a1 not modelled 27.1 13 Fold:DEATH domain Superfamily:DEATH domain Family:DEATH domain, DD 45 c2khxA_ not modelled 24.8 23 PDB header:gene regulation,nuclear protein Chain: A: PDB Molecule:ribonuclease 3; PDBTitle: drosha double-stranded rna binding motif 46 d1r8ea1 not modelled 24.0 2 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:DNA-binding N-terminal domain of transcription activators 47 d1qu6a1 not modelled 22.9 24 Fold:dsRBD-like Superfamily:dsRNA-binding domain-like Family:Double-stranded RNA-binding domain (dsRBD) 48 d1x49a1 not modelled 20.7 26 Fold:dsRBD-like Superfamily:dsRNA-binding domain-like Family:Double-stranded RNA-binding domain (dsRBD) 49 d1uxca_ not modelled 18.7 10 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 50 d1x47a1 not modelled 16.9 20 Fold:dsRBD-like Superfamily:dsRNA-binding domain-like Family:Double-stranded RNA-binding domain (dsRBD) 51 c3qaoA_ not modelled 16.9 13 PDB header:transcription regulator Chain: A: PDB Molecule:merr-like transcriptional regulator; PDBTitle: the crystal structure of the n-terminal domain of a merr-like2 transcriptional regulator from listeria monocytogenes egd-e 52 c3hh0C_ not modelled 16.7 11 PDB header:transcription regulator Chain: C: PDB Molecule:transcriptional regulator, merr family; PDBTitle: crystal strucure of a transcriptional regulator, merr family2 from bacillus cereus 53 c3adjA_ not modelled 16.5 14 PDB header:gene regulation Chain: A: PDB Molecule:f21m12.9 protein; PDBTitle: structure of arabidopsis hyl1 and its molecular implications for mirna2 processing 54 d1o0wa2 not modelled 16.0 22 Fold:dsRBD-like Superfamily:dsRNA-binding domain-like Family:Double-stranded RNA-binding domain (dsRBD) 55 c2zhhA_ not modelled 15.6 16 PDB header:transcription Chain: A: PDB Molecule:redox-sensitive transcriptional activator soxr; PDBTitle: crystal structure of soxr 56 c3adiC_ not modelled 15.3 18 PDB header:gene regulation/rna Chain: C: PDB Molecule:f21m12.9 protein; PDBTitle: structure of arabidopsis hyl1 and its molecular implications for mirna2 processing 57 c2l8nA_ not modelled 14.3 4 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional repressor cytr; PDBTitle: nmr structure of the cytidine repressor dna binding domain in presence2 of operator half-site dna 58 c2yt4A_ not modelled 13.2 20 PDB header:rna binding protein Chain: A: PDB Molecule:protein dgcr8; PDBTitle: crystal structure of human dgcr8 core 59 c2vz4A_ not modelled 12.9 19 PDB header:transcription Chain: A: PDB Molecule:hth-type transcriptional activator tipa; PDBTitle: the n-terminal domain of merr-like protein tipal bound to2 promoter dna 60 d2auwa1 not modelled 12.2 13 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:NE0471 C-terminal domain-like 61 d1rkta1 not modelled 11.8 11 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Tetracyclin repressor-like, N-terminal domain 62 d1uxda_ not modelled 11.6 4 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 63 d1fada_ not modelled 10.7 9 Fold:DEATH domain Superfamily:DEATH domain Family:DEATH domain, DD 64 c3ga7A_ not modelled 10.5 12 PDB header:hydrolase Chain: A: PDB Molecule:acetyl esterase; PDBTitle: 1.55 angstrom crystal structure of an acetyl esterase from salmonella2 typhimurium 65 d2b7va1 not modelled 10.5 22 Fold:dsRBD-like Superfamily:dsRNA-binding domain-like Family:Double-stranded RNA-binding domain (dsRBD) 66 d1lcda_ not modelled 9.6 4 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 67 c2gf5A_ not modelled 9.4 10 PDB header:apoptosis Chain: A: PDB Molecule:fadd protein; PDBTitle: structure of intact fadd (mort1) 68 c2x0lB_ not modelled 8.8 13 PDB header:transcription Chain: B: PDB Molecule:rest corepressor 1; PDBTitle: crystal structure of a neuro-specific splicing variant of2 human histone lysine demethylase lsd1. 69 c2v1dB_ not modelled 8.8 13 PDB header:oxidoreductase/repressor Chain: B: PDB Molecule:rest corepressor 1; PDBTitle: structural basis of lsd1-corest selectivity in histone h32 recognition 70 c2iw5B_ not modelled 8.8 13 PDB header:oxidoreductase/transcription regulator Chain: B: PDB Molecule:rest corepressor 1; PDBTitle: structural basis for corest-dependent demethylation of2 nucleosomes by the human lsd1 histone demethylase 71 c2xajB_ not modelled 8.8 13 PDB header:transcription Chain: B: PDB Molecule:rest corepressor 1; PDBTitle: crystal structure of lsd1-corest in complex with (-)-trans-2 2-phenylcyclopropyl-1-amine 72 c2lcvA_ not modelled 8.4 4 PDB header:transcription regulator Chain: A: PDB Molecule:hth-type transcriptional repressor cytr; PDBTitle: structure of the cytidine repressor dna-binding domain; an alternate2 calculation 73 d2bjca1 not modelled 8.3 4 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 74 d1qpza1 not modelled 7.7 0 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 75 c3gpvA_ not modelled 7.6 5 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, merr family; PDBTitle: crystal structure of a transcriptional regulator, merr2 family from bacillus thuringiensis 76 d2g7la1 not modelled 7.5 11 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Tetracyclin repressor-like, N-terminal domain 77 d2b7ta1 not modelled 7.5 16 Fold:dsRBD-like Superfamily:dsRNA-binding domain-like Family:Double-stranded RNA-binding domain (dsRBD) 78 d2iw5b1 not modelled 7.4 13 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Myb/SANT domain 79 d2csba1 not modelled 7.4 17 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Topoisomerase V repeat domain 80 c3ol0C_ not modelled 7.3 18 PDB header:de novo protein Chain: C: PDB Molecule:de novo designed monomer trefoil-fold sub-domain which PDBTitle: crystal structure of monofoil-4p homo-trimer: de novo designed monomer2 trefoil-fold sub-domain which forms homo-trimer assembly 81 c1yd2A_ not modelled 7.3 17 PDB header:dna binding protein Chain: A: PDB Molecule:uvrabc system protein c; PDBTitle: crystal structure of the giy-yig n-terminal endonuclease domain of2 uvrc from thermotoga maritima: point mutant y19f bound to the3 catalytic divalent cation 82 c2eqrA_ not modelled 7.2 16 PDB header:transcription Chain: A: PDB Molecule:nuclear receptor corepressor 1; PDBTitle: solution structure of the first sant domain from human2 nuclear receptor corepressor 1 83 d1xc5a1 not modelled 7.0 15 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Myb/SANT domain 84 c2k4zA_ not modelled 7.0 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dsrr; PDBTitle: solution nmr structure of allochromatium vinosum dsrr:2 northeast structural genomics consortium target op5 85 d1j6xa_ not modelled 6.8 18 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:Autoinducer-2 production protein LuxS 86 c2j8pA_ not modelled 6.7 33 PDB header:nuclear protein Chain: A: PDB Molecule:cleavage stimulation factor 64 kda subunit; PDBTitle: nmr structure of c-terminal domain of human cstf-64 87 c1qu6A_ not modelled 6.7 24 PDB header:transferase Chain: A: PDB Molecule:protein kinase pkr; PDBTitle: structure of the double-stranded rna-binding domain of the2 protein kinase pkr reveals the molecular basis of its3 dsrna-mediated activation 88 d1wi9a_ not modelled 6.7 21 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:PCI domain (PINT motif) 89 d1bb8a_ not modelled 6.5 23 Fold:DNA-binding domain Superfamily:DNA-binding domain Family:DNA-binding domain from tn916 integrase 90 c2l3jA_ not modelled 6.4 22 PDB header:hydrolase/rna Chain: A: PDB Molecule:double-stranded rna-specific editase 1; PDBTitle: the solution structure of the adar2 dsrbm-rna complex reveals a2 sequence-specific read out of the minor groove 91 d1vmha_ not modelled 6.4 17 Fold:YjbQ-like Superfamily:YjbQ-like Family:YjbQ-like 92 c2ae3A_ not modelled 6.3 7 PDB header:hydrolase Chain: A: PDB Molecule:glutaryl 7-aminocephalosporanic acid acylase; PDBTitle: glutaryl 7-aminocephalosporanic acid acylase: mutational study of2 activation mechanism 93 d2hsga1 not modelled 6.2 4 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 94 d1vz0a1 not modelled 6.2 10 Fold:DNA/RNA-binding 3-helical bundle Superfamily:KorB DNA-binding domain-like Family:KorB DNA-binding domain-like 95 d1zk8a1 not modelled 6.2 16 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Tetracyclin repressor-like, N-terminal domain 96 c3lgbB_ not modelled 6.1 10 PDB header:transferase Chain: B: PDB Molecule:dna primase large subunit; PDBTitle: crystal structure of the fe-s domain of the yeast dna primase 97 d1j6wa_ not modelled 6.1 24 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:Autoinducer-2 production protein LuxS 98 d1efaa1 not modelled 6.1 4 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:GalR/LacI-like bacterial regulator 99 d2g39a2 not modelled 6.1 13 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:CoA transferase alpha subunit-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0