Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	K	I	S	L	P	K	I	G	I	R	P	V	I	D	G	R	R	M	G	V	R	E	S	L	E	E	Q	T	M	N	M	A	K	A	T	A	A	L	L	T	E	K	L	R	H	A	C	G	A	A	V	E	C	V	I	S	D	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?									?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		C	I	A	G	M	A	E	A	A	A	C	E	E	K	F	S	S	Q	N	V	G	L	T	I	T	V	T	P	C	W	C	Y	G	S	E	T	I	D	M	D	P	T	R	P	K	A	I	W	G	F	N	G	T	E	R	P	G	A	V	Y
Secondary structure
SS confidence
Disorder			?	?	?																																			?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	A	A	A	L	A	A	H	S	Q	K	G	I	P	A	F	S	I	Y	G	H	D	V	Q	D	A	D	D	T	S	I	P	A	D	V	E	E	K	L	L	R	F	A	R	A	G	L	A	V	A	S	M	K	G	K	S	Y	L	S	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	G	V	S	M	G	I	A	G	S	I	V	D	H	N	F	F	E	S	W	L	G	M	K	V	Q	A	V	D	M	T	E	L	R	R	R	I	D	Q	K	I	Y	D	E	A	E	L	E	M	A	L	A	W	A	D	K	N	F	R	Y
Secondary structure
SS confidence
Disorder																																								?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	E	D	E	N	N	K	Q	Y	Q	R	N	A	E	Q	S	R	A	V	L	R	E	S	L	L	M	A	M	C	I	R	D	M	M	Q	G	N	S	K	L	A	D	I	G	R	V	E	E	S	L	G	Y	N	A	I	A	A	G	F	Q
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?	?																								?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	Q	R	H	W	T	D	Q	Y	P	N	G	D	T	A	E	A	I	L	N	S	S	F	D	W	N	G	V	R	E	P	F	V	V	A	T	E	N	D	S	L	N	G	V	A	M	L	M	G	H	Q	L	T	G	T	A	Q	V	F	A
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		D	V	R	T	Y	W	S	P	E	A	I	E	R	V	T	G	H	K	L	D	G	L	A	E	H	G	I	I	H	L	I	N	S	G	S	A	A	L	D	G	S	C	K	Q	R	D	S	E	G	N	P	T	M	K	P	H	W	E	I	S
Secondary structure
SS confidence
Disorder																						?																					?	?	?	?	?	?	?	?	?	?				?				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		Q	Q	E	A	D	A	C	L	A	A	T	E	W	C	P	A	I	H	E	Y	F	R	G	G	G	Y	S	S	R	F	L	T	E	G	G	V	P	F	T	M	T	R	V	N	I	I	K	G	L	G	P	V	L	Q	I	A	E	G	W	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?			?		?					?	?	?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		V	E	L	P	K	D	V	H	D	I	L	N	K	R	T	N	S	T	W	P	T	T	W	F	A	P	R	L	T	G	K	G	P	F	T	D	V	Y	S	V	M	A	N	W	G	A	N	H	G	V	L	T	I	G	H	V	G	A	D	F
Secondary structure
SS confidence
Disorder														?	?																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.
Sequence		I	T	L	A	S	M	L	R	I	P	V	C	M	H	N	V	E	E	T	K	V	Y	R	P	S	A	W	A	A	H	G	M	D	I	E	G	Q	D	Y	R	A	C	Q	N	Y	G	P	L	Y	K	R
Secondary structure
SS confidence
Disorder																											?		?	?	?	?			?	?				?							?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1fui chain B Region: 1 - 591 Aligned: 591 Modelled: 591 Confidence: 100.0% Identity: 100% PDB header:isomerase Chain: B: PDB Molecule:l-fucose isomerase; PDBTitle: l-fucose isomerase from escherichia coli Phyre2 PDB 3a9r chain A Region: 6 - 582 Aligned: 572 Modelled: 577 Confidence: 100.0% Identity: 65% PDB header:isomerase Chain: A: PDB Molecule:d-arabinose isomerase; PDBTitle: x-ray structures of bacillus pallidus d-arabinose2 isomerasecomplex with (4r)-2-methylpentane-2,4-diol Phyre2 PDB 1fui chain A domain 1 Region: 356 - 591 Aligned: 236 Modelled: 236 Confidence: 100.0% Identity: 100% Fold: Reductase/isomerase/elongation factor common domain Superfamily: FucI/AraA C-terminal domain-like Family: L-fucose isomerase, C-terminal domain Phyre2 PDB 1fui chain A domain 2 Region: 1 - 355 Aligned: 355 Modelled: 355 Confidence: 100.0% Identity: 100% Fold: FucI/AraA N-terminal and middle domains Superfamily: FucI/AraA N-terminal and middle domains Family: L-fucose isomerase, N-terminal and second domains Phyre2 PDB 2ajt chain A domain 2 Region: 1 - 357 Aligned: 309 Modelled: 342 Confidence: 100.0% Identity: 11% Fold: FucI/AraA N-terminal and middle domains Superfamily: FucI/AraA N-terminal and middle domains Family: AraA N-terminal and middle domain-like Phyre2 PDB 2hxg chain B Region: 14 - 559 Aligned: 440 Modelled: 487 Confidence: 100.0% Identity: 15% PDB header:isomerase Chain: B: PDB Molecule:l-arabinose isomerase; PDBTitle: crystal structure of mn2+ bound ecai Phyre2 PDB 2ajt chain A domain 1 Region: 442 - 559 Aligned: 106 Modelled: 118 Confidence: 83.6% Identity: 19% Fold: Reductase/isomerase/elongation factor common domain Superfamily: FucI/AraA C-terminal domain-like Family: AraA C-terminal domain-like Phyre2 PDB 1kfi chain A domain 1 Region: 16 - 164 Aligned: 127 Modelled: 137 Confidence: 83.0% Identity: 15% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 3pmg chain A domain 1 Region: 20 - 164 Aligned: 115 Modelled: 123 Confidence: 82.4% Identity: 15% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 1mkz chain A Region: 8 - 89 Aligned: 67 Modelled: 80 Confidence: 78.6% Identity: 16% Fold: Molybdenum cofactor biosynthesis proteins Superfamily: Molybdenum cofactor biosynthesis proteins Family: MogA-like Phyre2 PDB 1xi8 chain A domain 3 Region: 7 - 86 Aligned: 57 Modelled: 61 Confidence: 77.0% Identity: 18% Fold: Molybdenum cofactor biosynthesis proteins Superfamily: Molybdenum cofactor biosynthesis proteins Family: MoeA central domain-like Phyre2 PDB 3lft chain A Region: 7 - 117 Aligned: 96 Modelled: 109 Confidence: 73.4% Identity: 13% PDB header:structure genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the abc domain in complex with l-trp from2 streptococcus pneumonia to 1.35a Phyre2 PDB 2iea chain A domain 3 Region: 64 - 232 Aligned: 127 Modelled: 139 Confidence: 72.1% Identity: 16% Fold: TK C-terminal domain-like Superfamily: TK C-terminal domain-like Family: Transketolase C-terminal domain-like Phyre2 PDB 3qfe chain B Region: 30 - 135 Aligned: 101 Modelled: 103 Confidence: 70.8% Identity: 9% PDB header:lyase Chain: B: PDB Molecule:putative dihydrodipicolinate synthase family protein; PDBTitle: crystal structures of a putative dihydrodipicolinate synthase family2 protein from coccidioides immitis Phyre2 PDB 2p10 chain D Region: 2 - 88 Aligned: 75 Modelled: 85 Confidence: 69.2% Identity: 15% PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution Phyre2 PDB 2pjk chain A Region: 7 - 89 Aligned: 69 Modelled: 83 Confidence: 68.8% Identity: 9% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:178aa long hypothetical molybdenum cofactor PDBTitle: structure of hypothetical molybdenum cofactor biosynthesis2 protein b from sulfolobus tokodaii Phyre2 PDB 2p10 chain A domain 1 Region: 2 - 89 Aligned: 76 Modelled: 77 Confidence: 67.0% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Mll9387-like Phyre2 PDB 1r9d chain A Region: 437 - 499 Aligned: 62 Modelled: 63 Confidence: 66.2% Identity: 19% Fold: PFL-like glycyl radical enzymes Superfamily: PFL-like glycyl radical enzymes Family: PFL-like Phyre2 PDB 3m9y chain B Region: 186 - 265 Aligned: 77 Modelled: 80 Confidence: 63.6% Identity: 17% PDB header:isomerase Chain: B: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase from methicillin2 resistant staphylococcus aureus at 1.9 angstrom resolution Phyre2 PDB 2f7w chain A domain 1 Region: 5 - 89 Aligned: 74 Modelled: 85 Confidence: 63.5% Identity: 20% Fold: Molybdenum cofactor biosynthesis proteins Superfamily: Molybdenum cofactor biosynthesis proteins Family: MogA-like Phyre2 1 c1fuiB_ 2 c3a9rA_ 3 d1fuia1 4 d1fuia2 5 d2ajta2 6 c2hxgB_ 7 d2ajta1 8 d1kfia1 9 d3pmga1 10 d1mkza_ 11 d1xi8a3 12 c3lftA_ 13 d2ieaa3 14 c3qfeB_ 15 c2p10D_ 16 c2pjkA_ 17 d2p10a1 18 d1r9da_ 19 c3m9yB_ 20 d2f7wa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130