Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP06971
DateThu Jan 5 10:59:36 GMT 2012
Unique Job IDd477b2f0ffa241fb

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1by5a_
Top template information
Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
Confidence and coverage
Confidence:100.0% Coverage: 93%
697 residues ( 93% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAAT
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Disorder  ??????????????









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   .........70.........80.........90.........100.........110.........120
Sequence  IAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEALSYTPGVSVGTRGASNTY
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   .........130.........140.........150.........160.........170.........180
Sequence  DHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLERAEIMRGPVSVLYGKSSPGG
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   .........190.........200.........210.........220.........230.........240
Sequence  LLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLDDDGVYSYRLTGLARSANAQQKG
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   .........250.........260.........270.........280.........290.........300
Sequence  SEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFN
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   .........310.........320.........330.........340.........350.........360
Sequence  EGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLRFAENKTSQNSVYGYGVCSDPANAYSK
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   .........370.........380.........390.........400.........410.........420
Sequence  QCAALAPADKGHYLARKYVVDDEKLQNFSVDTQLQSKFATGDIDHTLLTGVDFMRMRNDI
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   .........430.........440.........450.........460.........470.........480
Sequence  NAWFGYDDSVPLLNLYNPVNTDFDFNAKDPANSGPYRILNKQKQTGVYVQDQAQWDKVLV
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   .........490.........500.........510.........520.........530.........540
Sequence  TLGGRYDWADQESLNRVAGTTDKRDDKQFTWRGGVNYLFDNGVTPYFSYSESFEPSSQVG
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   .........550.........560.........570.........580.........590.........600
Sequence  KDGNIFAPSKGKQYEVGVKYVPEDRPIVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRA
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   .........610.........620.........630.........640.........650.........660
Sequence  RGVEIEAKAALSASVNVVGSYTYTDAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPL
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   .........670.........680.........690.........700.........710.........720
Sequence  SGLTLGTGGRYTGSSYGDPANSFKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDRE
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   .........730.........740.......
Sequence  YVASCFNTYGCFWGAERQVVATATFRF
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?
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1by5 chain A

3D model

Region: 51 - 747
Aligned: 697
Modelled: 697
Confidence: 100.0%
Identity: 100%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 2grx chain B

3D model

Region: 52 - 747
Aligned: 691
Modelled: 691
Confidence: 100.0%
Identity: 100%
PDB header:metal transport
Chain: B: PDB Molecule:ferrichrome-iron receptor;
PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome

Phyre2

PDB 3qlb chain A

3D model

Region: 51 - 747
Aligned: 669
Modelled: 674
Confidence: 100.0%
Identity: 35%
PDB header:metal transport
Chain: A: PDB Molecule:enantio-pyochelin receptor;
PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin

Phyre2

PDB 2iah chain A

3D model

Region: 3 - 747
Aligned: 697
Modelled: 716
Confidence: 100.0%
Identity: 19%
PDB header:membrane protein
Chain: A: PDB Molecule:ferripyoverdine receptor;
PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine.

Phyre2

PDB 1xkh chain C

3D model

Region: 44 - 747
Aligned: 665
Modelled: 652
Confidence: 100.0%
Identity: 19%
PDB header:membrane protein
Chain: C: PDB Molecule:ferripyoverdine receptor;
PDBTitle: pyoverdine outer membrane receptor fpva from pseudomonas aeruginosa2 pao1 bound to pyoverdine

Phyre2

PDB 1xkw chain A

3D model

Region: 56 - 747
Aligned: 646
Modelled: 671
Confidence: 100.0%
Identity: 20%
PDB header:membrane protein
Chain: A: PDB Molecule:fe(iii)-pyochelin receptor;
PDBTitle: pyochelin outer membrane receptor fpta from pseudomonas2 aeruginosa

Phyre2

PDB 1kmo chain A

3D model

Region: 64 - 747
Aligned: 623
Modelled: 629
Confidence: 100.0%
Identity: 17%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 3fhh chain A

3D model

Region: 63 - 747
Aligned: 582
Modelled: 604
Confidence: 100.0%
Identity: 18%
PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane heme receptor shua;
PDBTitle: crystal structure of the heme/hemoglobin outer membrane2 transporter shua from shigella dysenteriae

Phyre2

PDB 1po3 chain A

3D model

Region: 74 - 747
Aligned: 613
Modelled: 619
Confidence: 100.0%
Identity: 16%
PDB header:membrane protein
Chain: A: PDB Molecule:iron(iii) dicitrate transport protein feca
PDBTitle: crystal structure of ferric citrate transporter feca in2 complex with ferric citrate

Phyre2

PDB 3efm chain A

3D model

Region: 50 - 726
Aligned: 561
Modelled: 586
Confidence: 100.0%
Identity: 20%
PDB header:membrane protein
Chain: A: PDB Molecule:ferric alcaligin siderophore receptor;
PDBTitle: structure of the alcaligin outer membrane recepteur faua from2 bordetella pertussis

Phyre2

PDB 2hdi chain A

3D model

Region: 63 - 747
Aligned: 564
Modelled: 595
Confidence: 100.0%
Identity: 16%
PDB header:protein transport,antimicrobial protein
Chain: A: PDB Molecule:colicin i receptor;
PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.

Phyre2

PDB 3csl chain B

3D model

Region: 73 - 747
Aligned: 640
Modelled: 649
Confidence: 100.0%
Identity: 16%
PDB header:membrane protein/heme binding protein
Chain: B: PDB Molecule:hasr protein;
PDBTitle: structure of the serratia marcescens hemophore receptor hasr in2 complex with its hemophore hasa and heme

Phyre2

PDB 2guf chain A domain 1

3D model

Region: 63 - 747
Aligned: 533
Modelled: 571
Confidence: 100.0%
Identity: 19%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 1fep chain A

3D model

Region: 63 - 747
Aligned: 626
Modelled: 633
Confidence: 100.0%
Identity: 15%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 1t16 chain A

3D model

Region: 509 - 747
Aligned: 230
Modelled: 239
Confidence: 99.5%
Identity: 13%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Outer membrane protein transport protein

Phyre2

PDB 3dwo chain X

3D model

Region: 462 - 700
Aligned: 236
Modelled: 239
Confidence: 98.8%
Identity: 11%
PDB header:membrane protein
Chain: X: PDB Molecule:probable outer membrane protein;
PDBTitle: crystal structure of a pseudomonas aeruginosa fadl homologue

Phyre2

PDB 3brz chain A

3D model

Region: 509 - 699
Aligned: 175
Modelled: 191
Confidence: 96.9%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:todx;
PDBTitle: crystal structure of the pseudomonas putida toluene2 transporter todx

Phyre2

PDB 2x27 chain X

3D model

Region: 564 - 747
Aligned: 180
Modelled: 184
Confidence: 95.6%
Identity: 13%
PDB header:membrane protein
Chain: X: PDB Molecule:outer membrane protein oprg;
PDBTitle: crystal structure of the outer membrane protein oprg from2 pseudomonas aeruginosa

Phyre2

PDB 2f1t chain B

3D model

Region: 602 - 747
Aligned: 140
Modelled: 146
Confidence: 95.3%
Identity: 15%
PDB header:membrane protein
Chain: B: PDB Molecule:outer membrane protein w;
PDBTitle: outer membrane protein ompw

Phyre2

PDB 3qra chain A

3D model

Region: 601 - 747
Aligned: 124
Modelled: 134
Confidence: 91.9%
Identity: 14%
PDB header:cell invasion
Chain: A: PDB Molecule:attachment invasion locus protein;
PDBTitle: the crystal structure of ail, the attachment invasion locus protein of2 yersinia pestis

Phyre2
1

d1by5a_
2

c2grxB_
3

c3qlbA_
4

c2iahA_
5

c1xkhC_
6

c1xkwA_
7

d1kmoa_
8

c3fhhA_
9

c1po3A_
10

c3efmA_
11

c2hdiA_
12

c3cslB_
13

d2gufa1
14

d1fepa_
15

d1t16a_
16

c3dwoX_
17

c3brzA_
18

c2x27X_
19

c2f1tB_
20

c3qraA_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1by5a_



100.0 100 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
2c2grxB_



100.0 100 PDB header:metal transport
Chain: B: PDB Molecule:ferrichrome-iron receptor;
PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome
3c3qlbA_



100.0 35 PDB header:metal transport
Chain: A: PDB Molecule:enantio-pyochelin receptor;
PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin
4c2iahA_



100.0 19 PDB header:membrane protein
Chain: A: PDB Molecule:ferripyoverdine receptor;
PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine.
5c1xkhC_



100.0 19 PDB header:membrane protein
Chain: C: PDB Molecule:ferripyoverdine receptor;
PDBTitle: pyoverdine outer membrane receptor fpva from pseudomonas aeruginosa2 pao1 bound to pyoverdine
6c1xkwA_



100.0 20 PDB header:membrane protein
Chain: A: PDB Molecule:fe(iii)-pyochelin receptor;
PDBTitle: pyochelin outer membrane receptor fpta from pseudomonas2 aeruginosa
7d1kmoa_



100.0 17 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
8c3fhhA_



100.0 18 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane heme receptor shua;
PDBTitle: crystal structure of the heme/hemoglobin outer membrane2 transporter shua from shigella dysenteriae
9c1po3A_



100.0 16 PDB header:membrane protein
Chain: A: PDB Molecule:iron(iii) dicitrate transport protein feca
PDBTitle: crystal structure of ferric citrate transporter feca in2 complex with ferric citrate
10c3efmA_



100.0 20 PDB header:membrane protein
Chain: A: PDB Molecule:ferric alcaligin siderophore receptor;
PDBTitle: structure of the alcaligin outer membrane recepteur faua from2 bordetella pertussis
11c2hdiA_



100.0 16 PDB header:protein transport,antimicrobial protein
Chain: A: PDB Molecule:colicin i receptor;
PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.
12c3cslB_



100.0 16 PDB header:membrane protein/heme binding protein
Chain: B: PDB Molecule:hasr protein;
PDBTitle: structure of the serratia marcescens hemophore receptor hasr in2 complex with its hemophore hasa and heme
13d2gufa1



100.0 19 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
14d1fepa_



100.0 15 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
15d1t16a_



99.5 13 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Outer membrane protein transport protein
16c3dwoX_



98.8 11 PDB header:membrane protein
Chain: X: PDB Molecule:probable outer membrane protein;
PDBTitle: crystal structure of a pseudomonas aeruginosa fadl homologue
17c3brzA_



96.9 11 PDB header:transport protein
Chain: A: PDB Molecule:todx;
PDBTitle: crystal structure of the pseudomonas putida toluene2 transporter todx
18c2x27X_



95.6 13 PDB header:membrane protein
Chain: X: PDB Molecule:outer membrane protein oprg;
PDBTitle: crystal structure of the outer membrane protein oprg from2 pseudomonas aeruginosa
19c2f1tB_



95.3 15 PDB header:membrane protein
Chain: B: PDB Molecule:outer membrane protein w;
PDBTitle: outer membrane protein ompw
20c3qraA_



91.9 14 PDB header:cell invasion
Chain: A: PDB Molecule:attachment invasion locus protein;
PDBTitle: the crystal structure of ail, the attachment invasion locus protein of2 yersinia pestis
21d1qj8a_



not modelled 84.0 11 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
22c2k0lA_



not modelled 83.6 11 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein a;
PDBTitle: nmr structure of the transmembrane domain of the outer2 membrane protein a from klebsiella pneumoniae in dhpc3 micelles.
23c3kvnA_



not modelled 83.0 10 PDB header:hydrolase
Chain: A: PDB Molecule:esterase esta;
PDBTitle: crystal structure of the full-length autotransporter esta from2 pseudomonas aeruginosa
24c3nb3C_



not modelled 82.2 10 PDB header:virus
Chain: C: PDB Molecule:outer membrane protein a;
PDBTitle: the host outer membrane proteins ompa and ompc are packed at specific2 sites in the shigella phage sf6 virion as structural components
25d1g90a_



not modelled 80.8 8 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
26d1qjpa_



not modelled 79.4 14 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
27c2wjqA_



not modelled 79.4 19 PDB header:transport protein
Chain: A: PDB Molecule:probable n-acetylneuraminic acid outer membrane channel
PDBTitle: nanc porin structure in hexagonal crystal form.
28c2jmmA_



not modelled 77.0 15 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein a;
PDBTitle: nmr solution structure of a minimal transmembrane beta-2 barrel platform protein
29d1p4ta_



not modelled 68.6 18 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
30d1uynx_



not modelled 67.9 9 Fold:Transmembrane beta-barrels
Superfamily:Autotransporter
Family:Autotransporter
31c2lhfA_



not modelled 67.4 27 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein h1;
PDBTitle: solution structure of outer membrane protein h (oprh) from p.2 aeruginosa in dhpc micelles
32c3bryB_



not modelled 60.1 12 PDB header:transport protein
Chain: B: PDB Molecule:tbux;
PDBTitle: crystal structure of the ralstonia pickettii toluene2 transporter tbux
33d2fgqx1



not modelled 55.9 14 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Porin
34c2y0kA_



not modelled 47.0 15 PDB header:transport protein
Chain: A: PDB Molecule:pyroglutatmate porin opdo;
PDBTitle: crystal structure of pseudomonas aeruginosa opdo
35c3k07A_



not modelled 42.9 10 PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
36d1osma_



not modelled 42.3 11 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Porin
37c3jtyB_



not modelled 42.1 12 PDB header:transport protein
Chain: B: PDB Molecule:benf-like porin;
PDBTitle: crystal structure of a benf-like porin from pseudomonas fluorescens2 pf-5
38c3fcgB_



not modelled 39.6 11 PDB header:membrane protein, protein transport
Chain: B: PDB Molecule:f1 capsule-anchoring protein;
PDBTitle: crystal structure analysis of the middle domain of the2 caf1a usher
39d1phoa_



not modelled 35.8 12 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Porin
40d1w0na_



not modelled 22.8 10 Fold:Galactose-binding domain-like
Superfamily:Galactose-binding domain-like
Family:Family 36 carbohydrate binding module, CBM36
41d2a1ja1



not modelled 17.0 40 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
42c2vqiA_



not modelled 15.7 16 PDB header:transport
Chain: A: PDB Molecule:outer membrane usher protein papc;
PDBTitle: structure of the p pilus usher (papc) translocation pore
43c3ohnA_



not modelled 14.2 15 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane usher protein fimd;
PDBTitle: crystal structure of the fimd translocation domain
44c2y0hA_



not modelled 14.0 13 PDB header:transport protein
Chain: A: PDB Molecule:probable porin;
PDBTitle: crystal structure of pseudomonas aeruginosa opdl
45d2zfga1



not modelled 10.5 15 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Porin
46c2iwvD_



not modelled 9.9 13 PDB header:ion channel
Chain: D: PDB Molecule:outer membrane protein g;
PDBTitle: structure of the monomeric outer membrane porin ompg in the2 open and closed conformation
47d1iwga6



not modelled 9.7 9 Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
48c3sljA_



not modelled 7.7 9 PDB header:protein transport
Chain: A: PDB Molecule:serine protease espp;
PDBTitle: pre-cleavage structure of the autotransporter espp - n1023a mutant
49c3nsgA_



not modelled 6.0 12 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein f;
PDBTitle: crystal structure of ompf, an outer membrane protein from salmonella2 typhi
50c2odjA_



not modelled 5.4 10 PDB header:membrane protein
Chain: A: PDB Molecule:porin d;
PDBTitle: crystal structure of the outer membrane protein oprd from pseudomonas2 aeruginosa
51d1gm5a2



not modelled 5.4 10 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:RecG "wedge" domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0