Email l.a.kelley@imperial.ac.uk Description P00888 Date Thu Jan 5 10:56:59 GMT 2012 Unique Job ID cfc2e7f9f51b6dff

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1n8fa_ 100.0 54 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 2 c3tqkA_ 100.0 46 PDB header:transferase Chain: A: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: structure of phospho-2-dehydro-3-deoxyheptonate aldolase from2 francisella tularensis schu s4 3 d1of8a_ 100.0 52 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 4 c1ofaB_ 100.0 52 PDB header:lyase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: crystal structure of the tyrosine-regulated2 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase3 from saccharomyces cerevisiae in complex with4 phosphoenolpyruvate and cobalt(ii) 5 d1vr6a1 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 6 c1vs1B_ 100.0 23 PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep 7 c1zcoA_ 100.0 21 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase; PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase 8 d2a21a1 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 9 c3nvtA_ 100.0 24 PDB header:transferase/isomerase Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e 10 c3stgA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis 11 c3fs2A_ 100.0 21 PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate2 aldolase from bruciella melitensis at 1.85a resolution 12 d1d9ea_ 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 13 d1o60a_ 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 14 c3t4cD_ 100.0 18 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria 15 c3sz8D_ 100.0 14 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei 16 c3pg8B_ 100.0 21 PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima 17 d2zdra2 99.6 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 18 d1vlia2 99.4 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 19 c1xuzA_ 99.0 14 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 20 c1vliA_ 98.8 15 PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution 21 d2b7oa1 not modelled 98.6 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class-II DAHP synthetase 22 c3g8rA_ not modelled 98.3 11 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 23 d1ad1a_ not modelled 94.6 13 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 24 d1ajza_ not modelled 92.7 21 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 25 c3eb2A_ not modelled 87.3 15 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 26 c2y5sA_ not modelled 86.8 24 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of burkholderia cenocepacia dihydropteroate2 synthase complexed with 7,8-dihydropteroate. 27 c2bmbA_ not modelled 82.7 14 PDB header:transferase Chain: A: PDB Molecule:folic acid synthesis protein fol1; PDBTitle: x-ray structure of the bifunctional 6-hydroxymethyl-7,8-2 dihydroxypterin pyrophosphokinase dihydropteroate synthase3 from saccharomyces cerevisiae 28 d1dxha1 not modelled 80.7 28 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 29 c2otcA_ not modelled 80.2 23 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine 30 c1ortD_ not modelled 78.6 29 PDB header:transferase Chain: D: PDB Molecule:ornithine transcarbamoylase; PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa 31 d1tx2a_ not modelled 77.8 17 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 32 c1tx2A_ not modelled 77.8 17 PDB header:transferase Chain: A: PDB Molecule:dhps, dihydropteroate synthase; PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis 33 d1duvg1 not modelled 67.1 23 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 34 c3updA_ not modelled 63.6 22 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus 35 d1eyea_ not modelled 63.5 16 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 36 c3e5bB_ not modelled 62.7 17 PDB header:lyase Chain: B: PDB Molecule:isocitrate lyase; PDBTitle: 2.4 a crystal structure of isocitrate lyase from brucella2 melitensis 37 d1sq5a_ not modelled 60.3 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Phosphoribulokinase/pantothenate kinase 38 d1f74a_ not modelled 57.6 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 39 c3fa4D_ not modelled 57.4 15 PDB header:lyase Chain: D: PDB Molecule:2,3-dimethylmalate lyase; PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form 40 c2hjpA_ not modelled 56.9 15 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 41 c1a1sA_ not modelled 56.2 26 PDB header:transcarbamylase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus 42 d1vlva1 not modelled 56.1 22 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 43 d1o5ka_ not modelled 55.0 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 44 c2p2gD_ not modelled 54.1 29 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form 45 c2ehhE_ not modelled 53.5 18 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 46 c3d6nB_ not modelled 53.2 19 PDB header:hydrolase/transferase Chain: B: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase 47 c1vlvA_ not modelled 52.6 21 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution 48 c3grfA_ not modelled 52.1 20 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia 49 c3si9B_ not modelled 51.3 16 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from bartonella2 henselae 50 c3gd5D_ not modelled 50.8 23 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus 51 c3noeA_ not modelled 50.4 17 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa 52 c2e3zB_ not modelled 47.4 27 PDB header:hydrolase Chain: B: PDB Molecule:beta-glucosidase; PDBTitle: crystal structure of intracellular family 1 beta-2 glucosidase bgl1a from the basidiomycete phanerochaete3 chrysosporium in substrate-free form 53 c3tqcB_ not modelled 46.7 11 PDB header:transferase Chain: B: PDB Molecule:pantothenate kinase; PDBTitle: structure of the pantothenate kinase (coaa) from coxiella burnetii 54 c3pueA_ not modelled 46.0 21 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution 55 c2v9dB_ not modelled 45.8 17 PDB header:lyase Chain: B: PDB Molecule:yage; PDBTitle: crystal structure of yage, a prophage protein belonging to2 the dihydrodipicolinic acid synthase family from e. coli3 k12 56 d1pvva1 not modelled 45.7 26 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 57 c2ze3A_ not modelled 44.2 15 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 58 c2w37A_ not modelled 42.8 24 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic; PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii 59 c3b4uB_ not modelled 42.5 16 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58 60 d1muma_ not modelled 40.3 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 61 c3bi8A_ not modelled 39.9 13 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of dihydrodipicolinate synthase from clostridium2 botulinum 62 c1fvoB_ not modelled 39.7 24 PDB header:transferase Chain: B: PDB Molecule:ornithine transcarbamylase; PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate 63 c3igxA_ not modelled 39.2 19 PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: 1.85 angstrom resolution crystal structure of transaldolase b (tala)2 from francisella tularensis. 64 c2vqqA_ not modelled 38.2 19 PDB header:hydrolase Chain: A: PDB Molecule:histone deacetylase 4; PDBTitle: structure of hdac4 catalytic domain (a double cysteine-to-2 alanine mutant) bound to a trifluoromethylketone inhbitor 65 c2ef0A_ not modelled 38.1 27 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus 66 c2ze5A_ not modelled 37.4 21 PDB header:transferase Chain: A: PDB Molecule:isopentenyl transferase; PDBTitle: crystal structure of adenosine phosphate-isopentenyltransferase 67 d2v3za1 not modelled 36.8 18 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 68 c2yxgD_ not modelled 36.8 23 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihyrodipicolinate synthase (dapa) 69 c3ptkB_ not modelled 36.7 23 PDB header:hydrolase Chain: B: PDB Molecule:beta-glucosidase os4bglu12; PDBTitle: the crystal structure of rice (oryza sativa l.) os4bglu12 70 d1igwa_ not modelled 36.4 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 71 c2qw5B_ not modelled 34.1 14 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase-like tim barrel; PDBTitle: crystal structure of a putative sugar phosphate isomerase/epimerase2 (ava4194) from anabaena variabilis atcc 29413 at 1.78 a resolution 72 d1pffa_ not modelled 34.0 18 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 73 c3g0sA_ not modelled 33.0 18 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 74 c3cprB_ not modelled 31.9 18 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 75 c3a8tA_ not modelled 31.7 26 PDB header:transferase Chain: A: PDB Molecule:adenylate isopentenyltransferase; PDBTitle: plant adenylate isopentenyltransferase in complex with atp 76 c3daqB_ not modelled 31.6 18 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus 77 c3oixA_ not modelled 31.2 15 PDB header:oxidoreductase Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans 78 c2p2sA_ not modelled 30.7 19 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase (yp_050235.1) from2 erwinia carotovora atroseptica scri1043 at 1.25 a resolution 79 c1f9cA_ not modelled 29.8 14 PDB header:isomerase Chain: A: PDB Molecule:protein (muconate cycloisomerase i); PDBTitle: crystal structure of mle d178n variant 80 c3fluD_ not modelled 29.4 16 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis 81 d2a6na1 not modelled 27.7 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 82 c3na8A_ not modelled 27.5 13 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of a putative dihydrodipicolinate synthetase from2 pseudomonas aeruginosa 83 c3ahyD_ not modelled 27.0 17 PDB header:hydrolase Chain: D: PDB Molecule:beta-glucosidase; PDBTitle: crystal structure of beta-glucosidase 2 from fungus trichoderma reesei2 in complex with tris 84 d1f05a_ not modelled 26.6 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 85 d2e1da1 not modelled 26.5 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 86 c2wamB_ not modelled 26.4 13 PDB header:unknown function Chain: B: PDB Molecule:conserved hypothetical alanine and leucine rich PDBTitle: crystal structure of mycobacterium tuberculosis unknown2 function protein rv2714 87 c2dzaA_ not modelled 25.8 16 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of dihydropteroate synthase from thermus2 thermophilus hb8 in complex with 4-aminobenzoate 88 c3s5oA_ not modelled 25.7 13 PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial; PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate 89 c2gqnB_ not modelled 25.3 18 PDB header:lyase Chain: B: PDB Molecule:cystathionine beta-lyase; PDBTitle: cystathionine beta-lyase (cbl) from escherichia coli in complex with2 n-hydrazinocarbonylmethyl-2-nitro-benzamide 90 d1e5ea_ not modelled 25.3 27 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 91 c3m16A_ not modelled 25.0 17 PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: structure of a transaldolase from oleispira antarctica 92 d1piia2 not modelled 24.9 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 93 c2cb1A_ not modelled 24.5 20 PDB header:lyase Chain: A: PDB Molecule:o-acetyl homoserine sulfhydrylase; PDBTitle: crystal structure of o-actetyl homoserine sulfhydrylase2 from thermus thermophilus hb8,oah2. 94 d1tuga1 not modelled 24.1 18 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 95 c2nmpC_ not modelled 23.5 24 PDB header:lyase Chain: C: PDB Molecule:cystathionine gamma-lyase; PDBTitle: crystal structure of human cystathionine gamma lyase 96 d1n8pa_ not modelled 23.4 35 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 97 c3d3qB_ not modelled 23.3 36 PDB header:transferase Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of trna delta(2)-isopentenylpyrophosphate2 transferase (se0981) from staphylococcus epidermidis.3 northeast structural genomics consortium target ser100 98 c3exaD_ not modelled 22.6 24 PDB header:transferase Chain: D: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of the full-length trna2 isopentenylpyrophosphate transferase (bh2366) from3 bacillus halodurans, northeast structural genomics4 consortium target bhr41. 99 c3gndC_ not modelled 22.2 17 PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate 100 d1qgna_ not modelled 22.1 29 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 101 c2rgwD_ not modelled 22.0 13 PDB header:transferase Chain: D: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase 102 d1ujqa_ not modelled 21.9 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 103 c3tr9A_ not modelled 21.6 15 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii 104 d2auwa1 not modelled 21.4 63 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:NE0471 C-terminal domain-like 105 c2jf7B_ not modelled 21.2 18 PDB header:hydrolase Chain: B: PDB Molecule:strictosidine-o-beta-d-glucosidase; PDBTitle: structure of strictosidine glucosidase 106 c2vc6A_ not modelled 20.2 19 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of mosa from s. meliloti with pyruvate bound