Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37595
DateThu Jan 5 11:55:41 GMT 2012
Unique Job IDbdb45a0974b871d2

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2zakB_
Top template information
PDB header:hydrolase
Chain: B: PDB Molecule:l-asparaginase precursor;
PDBTitle: orthorhombic crystal structure of precursor e. coli isoaspartyl2 peptidase/l-asparaginase (ecaiii) with active-site t179a mutation
Confidence and coverage
Confidence:100.0% Coverage: 91%
293 residues ( 91% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MGKAVIAIHGGAGAISRAQMSLQQELRYIEALSAIVETGQKMLEAGESALDVVTEAVRLL
Secondary structure 















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Disorder  ??














????






















?














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   .........70.........80.........90.........100.........110.........120
Sequence  EECPLFNAGIGAVFTRDETHELDACVMDGNTLKAGAVAGVSHLRNPVLAARLVMEQSPHV
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   .........130.........140.........150.........160.........170.........180
Sequence  MMIGEGAENFAFARGMERVSPEIFSTSLRYEQLLAARKEGATVLDHSGAPLDEKQKMGTV
Secondary structure 


































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Disorder 



















?
??












???????????????







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   .........190.........200.........210.........220.........230.........240
Sequence  GAVALDLDGNLAAATSTGGMTNKLPGRVGDSPLVGAGCYANNASVAVSCTGTGEVFIRAL
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?





































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   .........250.........260.........270.........280.........290.........300
Sequence  AAYDIAALMDYGGLSLAEACERVVMEKLPALGGSGGLIAIDHEGNVALPFNTEGMYRAWG
Secondary structure 















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Disorder 










??















??




























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   .........310.........320.
Sequence  YAGDTPTTGIYREKGDTVATQ
Secondary structure 












SS confidence 




















Disorder 











?????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2zak chain B

3D model

Region: 2 - 313
Aligned: 293
Modelled: 293
Confidence: 100.0%
Identity: 99%
PDB header:hydrolase
Chain: B: PDB Molecule:l-asparaginase precursor;
PDBTitle: orthorhombic crystal structure of precursor e. coli isoaspartyl2 peptidase/l-asparaginase (ecaiii) with active-site t179a mutation

Phyre2

PDB 1p4v chain A

3D model

Region: 33 - 315
Aligned: 272
Modelled: 282
Confidence: 100.0%
Identity: 34%
PDB header:hydrolase
Chain: A: PDB Molecule:n(4)-(beta-n-acetylglucosaminyl)-l-asparaginase
PDBTitle: crystal structure of the glycosylasparaginase precursor2 d151n mutant with glycine

Phyre2

PDB 2a8l chain B

3D model

Region: 3 - 321
Aligned: 275
Modelled: 281
Confidence: 100.0%
Identity: 36%
PDB header:hydrolase
Chain: B: PDB Molecule:threonine aspartase 1;
PDBTitle: crystal structure of human taspase1 (t234a mutant)

Phyre2

PDB 1t3m chain A

3D model

Region: 2 - 157
Aligned: 156
Modelled: 156
Confidence: 100.0%
Identity: 100%
PDB header:hydrolase
Chain: A: PDB Molecule:putative l-asparaginase;
PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli

Phyre2

PDB 2gez chain E

3D model

Region: 2 - 167
Aligned: 165
Modelled: 166
Confidence: 100.0%
Identity: 40%
PDB header:hydrolase
Chain: E: PDB Molecule:l-asparaginase alpha subunit;
PDBTitle: crystal structure of potassium-independent plant asparaginase

Phyre2

PDB 2zal chain D

3D model

Region: 179 - 314
Aligned: 136
Modelled: 135
Confidence: 100.0%
Identity: 99%
PDB header:hydrolase
Chain: D: PDB Molecule:l-asparaginase;
PDBTitle: crystal structure of e. coli isoaspartyl aminopeptidase/l-asparaginase2 in complex with l-aspartate

Phyre2

PDB 2zal chain B

3D model

Region: 179 - 316
Aligned: 138
Modelled: 135
Confidence: 100.0%
Identity: 99%
PDB header:hydrolase
Chain: B: PDB Molecule:l-asparaginase;
PDBTitle: crystal structure of e. coli isoaspartyl aminopeptidase/l-asparaginase2 in complex with l-aspartate

Phyre2

PDB 1k2x chain B

3D model

Region: 179 - 313
Aligned: 135
Modelled: 135
Confidence: 100.0%
Identity: 100%
PDB header:hydrolase
Chain: B: PDB Molecule:putative l-asparaginase;
PDBTitle: crystal structure of putative asparaginase encoded by escherichia coli2 ybik gene

Phyre2

PDB 1k2x chain D

3D model

Region: 179 - 313
Aligned: 135
Modelled: 135
Confidence: 100.0%
Identity: 100%
PDB header:hydrolase
Chain: D: PDB Molecule:putative l-asparaginase;
PDBTitle: crystal structure of putative asparaginase encoded by escherichia coli2 ybik gene

Phyre2

PDB 1jn9 chain D

3D model

Region: 179 - 313
Aligned: 135
Modelled: 135
Confidence: 100.0%
Identity: 100%
PDB header:hydrolase
Chain: D: PDB Molecule:putative l-asparaginase;
PDBTitle: structure of putative asparaginase encoded by escherichia coli ybik2 gene

Phyre2

PDB 1t3m chain D

3D model

Region: 179 - 312
Aligned: 134
Modelled: 134
Confidence: 100.0%
Identity: 100%
PDB header:hydrolase
Chain: D: PDB Molecule:putative l-asparaginase;
PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli

Phyre2

PDB 1jn9 chain B

3D model

Region: 179 - 312
Aligned: 134
Modelled: 134
Confidence: 100.0%
Identity: 100%
PDB header:hydrolase
Chain: B: PDB Molecule:putative l-asparaginase;
PDBTitle: structure of putative asparaginase encoded by escherichia coli ybik2 gene

Phyre2

PDB 1t3m chain B

3D model

Region: 179 - 312
Aligned: 134
Modelled: 134
Confidence: 100.0%
Identity: 100%
PDB header:hydrolase
Chain: B: PDB Molecule:putative l-asparaginase;
PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli

Phyre2

PDB 1apy chain A

3D model

Region: 33 - 173
Aligned: 141
Modelled: 141
Confidence: 100.0%
Identity: 26%
PDB header:hydrolase
Chain: A: PDB Molecule:aspartylglucosaminidase;
PDBTitle: human aspartylglucosaminidase

Phyre2

PDB 2gez chain F

3D model

Region: 179 - 311
Aligned: 130
Modelled: 133
Confidence: 100.0%
Identity: 55%
PDB header:hydrolase
Chain: F: PDB Molecule:l-asparaginase beta subunit;
PDBTitle: crystal structure of potassium-independent plant asparaginase

Phyre2

PDB 2gac chain A

3D model

Region: 33 - 155
Aligned: 122
Modelled: 123
Confidence: 100.0%
Identity: 36%
PDB header:hydrolase
Chain: A: PDB Molecule:glycosylasparaginase;
PDBTitle: t152c mutant glycosylasparaginase from flavobacterium2 meningosepticum

Phyre2

PDB 2gac chain D

3D model

Region: 180 - 305
Aligned: 125
Modelled: 126
Confidence: 100.0%
Identity: 34%
PDB header:hydrolase
Chain: D: PDB Molecule:glycosylasparaginase;
PDBTitle: t152c mutant glycosylasparaginase from flavobacterium2 meningosepticum

Phyre2

PDB 1apz chain B

3D model

Region: 179 - 309
Aligned: 130
Modelled: 131
Confidence: 100.0%
Identity: 32%
PDB header:complex (hydrolase/peptide)
Chain: B: PDB Molecule:aspartylglucosaminidase;
PDBTitle: human aspartylglucosaminidase complex with reaction product

Phyre2

PDB 2e0w chain A

3D model

Region: 139 - 261
Aligned: 120
Modelled: 123
Confidence: 97.0%
Identity: 19%
PDB header:transferase
Chain: A: PDB Molecule:gamma-glutamyltranspeptidase;
PDBTitle: t391a precursor mutant protein of gamma-glutamyltranspeptidase from2 escherichia coli

Phyre2

PDB 2e0y chain B

3D model

Region: 179 - 261
Aligned: 68
Modelled: 83
Confidence: 95.0%
Identity: 37%
PDB header:transferase
Chain: B: PDB Molecule:gamma-glutamyltranspeptidase;
PDBTitle: crystal structure of the samarium derivative of mature gamma-2 glutamyltranspeptidase from escherichia coli

Phyre2
1

c2zakB_
2

c1p4vA_
3

c2a8lB_
4

c1t3mA_
5

c2gezE_
6

c2zalD_
7

c2zalB_
8

c1k2xB_
9

c1k2xD_
10

c1jn9D_
11

c1t3mD_
12

c1jn9B_
13

c1t3mB_
14

c1apyA_
15

c2gezF_
16

c2gacA_
17

c2gacD_
18

c1apzB_
19

c2e0wA_
20

c2e0yB_
21



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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2zakB_



100.0 99 PDB header:hydrolase
Chain: B: PDB Molecule:l-asparaginase precursor;
PDBTitle: orthorhombic crystal structure of precursor e. coli isoaspartyl2 peptidase/l-asparaginase (ecaiii) with active-site t179a mutation
2c1p4vA_



100.0 34 PDB header:hydrolase
Chain: A: PDB Molecule:n(4)-(beta-n-acetylglucosaminyl)-l-asparaginase
PDBTitle: crystal structure of the glycosylasparaginase precursor2 d151n mutant with glycine
3c2a8lB_



100.0 36 PDB header:hydrolase
Chain: B: PDB Molecule:threonine aspartase 1;
PDBTitle: crystal structure of human taspase1 (t234a mutant)
4c1t3mA_



100.0 100 PDB header:hydrolase
Chain: A: PDB Molecule:putative l-asparaginase;
PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli
5c2gezE_



100.0 40 PDB header:hydrolase
Chain: E: PDB Molecule:l-asparaginase alpha subunit;
PDBTitle: crystal structure of potassium-independent plant asparaginase
6c2zalD_



100.0 99 PDB header:hydrolase
Chain: D: PDB Molecule:l-asparaginase;
PDBTitle: crystal structure of e. coli isoaspartyl aminopeptidase/l-asparaginase2 in complex with l-aspartate
7c2zalB_



100.0 99 PDB header:hydrolase
Chain: B: PDB Molecule:l-asparaginase;
PDBTitle: crystal structure of e. coli isoaspartyl aminopeptidase/l-asparaginase2 in complex with l-aspartate
8c1k2xB_



100.0 100 PDB header:hydrolase
Chain: B: PDB Molecule:putative l-asparaginase;
PDBTitle: crystal structure of putative asparaginase encoded by escherichia coli2 ybik gene
9c1k2xD_



100.0 100 PDB header:hydrolase
Chain: D: PDB Molecule:putative l-asparaginase;
PDBTitle: crystal structure of putative asparaginase encoded by escherichia coli2 ybik gene
10c1jn9D_



100.0 100 PDB header:hydrolase
Chain: D: PDB Molecule:putative l-asparaginase;
PDBTitle: structure of putative asparaginase encoded by escherichia coli ybik2 gene
11c1t3mD_



100.0 100 PDB header:hydrolase
Chain: D: PDB Molecule:putative l-asparaginase;
PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli
12c1jn9B_



100.0 100 PDB header:hydrolase
Chain: B: PDB Molecule:putative l-asparaginase;
PDBTitle: structure of putative asparaginase encoded by escherichia coli ybik2 gene
13c1t3mB_



100.0 100 PDB header:hydrolase
Chain: B: PDB Molecule:putative l-asparaginase;
PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli
14c1apyA_



100.0 26 PDB header:hydrolase
Chain: A: PDB Molecule:aspartylglucosaminidase;
PDBTitle: human aspartylglucosaminidase
15c2gezF_



100.0 55 PDB header:hydrolase
Chain: F: PDB Molecule:l-asparaginase beta subunit;
PDBTitle: crystal structure of potassium-independent plant asparaginase
16c2gacA_



100.0 36 PDB header:hydrolase
Chain: A: PDB Molecule:glycosylasparaginase;
PDBTitle: t152c mutant glycosylasparaginase from flavobacterium2 meningosepticum
17c2gacD_



100.0 34 PDB header:hydrolase
Chain: D: PDB Molecule:glycosylasparaginase;
PDBTitle: t152c mutant glycosylasparaginase from flavobacterium2 meningosepticum
18c1apzB_



100.0 32 PDB header:complex (hydrolase/peptide)
Chain: B: PDB Molecule:aspartylglucosaminidase;
PDBTitle: human aspartylglucosaminidase complex with reaction product
19c2e0wA_



97.0 19 PDB header:transferase
Chain: A: PDB Molecule:gamma-glutamyltranspeptidase;
PDBTitle: t391a precursor mutant protein of gamma-glutamyltranspeptidase from2 escherichia coli
20c2e0yB_



95.0 37 PDB header:transferase
Chain: B: PDB Molecule:gamma-glutamyltranspeptidase;
PDBTitle: crystal structure of the samarium derivative of mature gamma-2 glutamyltranspeptidase from escherichia coli
21d2nlza1



not modelled 94.6 26 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Gamma-glutamyltranspeptidase-like
22c2z8jA_



not modelled 94.5 14 PDB header:transferase
Chain: A: PDB Molecule:gamma-glutamyltranspeptidase;
PDBTitle: crystal structure of escherichia coli gamma-2 glutamyltranspeptidase in complex with azaserine prepared3 in the dark
23c2qm6C_



not modelled 93.3 32 PDB header:transferase
Chain: C: PDB Molecule:gamma-glutamyltranspeptidase;
PDBTitle: crystal structure of helicobacter pylori gamma-glutamyltranspeptidase2 in complex with glutamate
24c2v36A_



not modelled 92.9 25 PDB header:transferase
Chain: A: PDB Molecule:gamma-glutamyltranspeptidase large chain;
PDBTitle: crystal structure of gamma-glutamyl transferase from2 bacillus subtilis
25c3g9kD_



not modelled 92.8 35 PDB header:hydrolase
Chain: D: PDB Molecule:capsule biosynthesis protein capd;
PDBTitle: crystal structure of bacillus anthracis transpeptidase enzyme capd
26d2i3oa1



not modelled 92.6 14 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Gamma-glutamyltranspeptidase-like
27c3ga9S_



not modelled 91.9 24 PDB header:hydrolase
Chain: S: PDB Molecule:capsule biosynthesis protein capd;
PDBTitle: crystal structure of bacillus anthracis transpeptidase enzyme capd,2 crystal form ii
28d2imha1



not modelled 91.7 20 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:SPO2555-like
29c2v36D_



not modelled 88.3 22 PDB header:transferase
Chain: D: PDB Molecule:gamma-glutamyltranspeptidase small chain;
PDBTitle: crystal structure of gamma-glutamyl transferase from2 bacillus subtilis
30c2nqoB_



not modelled 78.9 22 PDB header:transferase
Chain: B: PDB Molecule:gamma-glutamyltranspeptidase;
PDBTitle: crystal structure of helicobacter pylori gamma-glutamyltranspeptidase
31d1k4ia_



not modelled 48.1 17 Fold:YrdC/RibB
Superfamily:YrdC/RibB
Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
32c2otdC_



not modelled 31.1 26 PDB header:hydrolase
Chain: C: PDB Molecule:glycerophosphodiester phosphodiesterase;
PDBTitle: the crystal structure of the glycerophosphodiester phosphodiesterase2 from shigella flexneri 2a
33d1hw8a2



not modelled 23.7 27 Fold:Substrate-binding domain of HMG-CoA reductase
Superfamily:Substrate-binding domain of HMG-CoA reductase
Family:Substrate-binding domain of HMG-CoA reductase
34c3mioA_



not modelled 23.2 13 PDB header:lyase
Chain: A: PDB Molecule:3,4-dihydroxy-2-butanone 4-phosphate synthase;
PDBTitle: crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase2 domain from mycobacterium tuberculosis at ph 6.00
35c1yy3A_



not modelled 21.5 22 PDB header:isomerase
Chain: A: PDB Molecule:s-adenosylmethionine:trna ribosyltransferase-
PDBTitle: structure of s-adenosylmethionine:trna ribosyltransferase-2 isomerase (quea)
36d1tqha_



not modelled 21.0 22 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase/lipase
37c3cdkD_



not modelled 19.0 32 PDB header:transferase
Chain: D: PDB Molecule:succinyl-coa:3-ketoacid-coenzyme a transferase
PDBTitle: crystal structure of the co-expressed succinyl-coa2 transferase a and b complex from bacillus subtilis
38d1tksa_



not modelled 19.0 11 Fold:YrdC/RibB
Superfamily:YrdC/RibB
Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
39d1g57a_



not modelled 18.5 19 Fold:YrdC/RibB
Superfamily:YrdC/RibB
Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
40d2nn6h2



not modelled 16.6 20 Fold:Barrel-sandwich hybrid
Superfamily:Ribosomal L27 protein-like
Family:ECR1 N-terminal domain-like
41d2djia1



not modelled 16.6 21 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
42d1k25a4



not modelled 16.2 13 Fold:beta-lactamase/transpeptidase-like
Superfamily:beta-lactamase/transpeptidase-like
Family:beta-Lactamase/D-ala carboxypeptidase
43c3m1eA_



not modelled 16.1 18 PDB header:transcription regulator
Chain: A: PDB Molecule:hth-type transcriptional regulator benm;
PDBTitle: crystal structure of benm_dbd
44d2ihta1



not modelled 15.8 25 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
45d1azwa_



not modelled 15.4 54 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
46d1t9ba1



not modelled 15.3 19 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
47d1dqaa4



not modelled 15.2 27 Fold:Substrate-binding domain of HMG-CoA reductase
Superfamily:Substrate-binding domain of HMG-CoA reductase
Family:Substrate-binding domain of HMG-CoA reductase
48d2phna1



not modelled 14.8 25 Fold:CofE-like
Superfamily:CofE-like
Family:CofE-like
49d1kyqa2



not modelled 14.8 30 Fold:Siroheme synthase middle domains-like
Superfamily:Siroheme synthase middle domains-like
Family:Siroheme synthase middle domains-like
50c2qruA_



not modelled 14.7 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis
51c1qgeD_



not modelled 14.6 46 PDB header:hydrolase
Chain: D: PDB Molecule:protein (triacylglycerol hydrolase);
PDBTitle: new crystal form of pseudomonas glumae (formerly chromobacterium2 viscosum atcc 6918) lipase
52c3hxkB_



not modelled 14.5 17 PDB header:hydrolase
Chain: B: PDB Molecule:sugar hydrolase;
PDBTitle: crystal structure of a sugar hydrolase (yeeb) from2 lactococcus lactis, northeast structural genomics3 consortium target kr108
53c3fnbB_



not modelled 14.3 18 PDB header:hydrolase
Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737;
PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159
54d1n9ba_



not modelled 14.0 19 Fold:beta-lactamase/transpeptidase-like
Superfamily:beta-lactamase/transpeptidase-like
Family:beta-Lactamase/D-ala carboxypeptidase
55c3ms6A_



not modelled 13.9 27 PDB header:protein binding
Chain: A: PDB Molecule:hepatitis b virus x-interacting protein;
PDBTitle: crystal structure of hepatitis b x-interacting protein (hbxip)
56d1zpda1



not modelled 13.8 19 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
57d2nn6i2



not modelled 13.8 25 Fold:Barrel-sandwich hybrid
Superfamily:Ribosomal L27 protein-like
Family:ECR1 N-terminal domain-like
58d1hw8c2



not modelled 13.7 27 Fold:Substrate-binding domain of HMG-CoA reductase
Superfamily:Substrate-binding domain of HMG-CoA reductase
Family:Substrate-binding domain of HMG-CoA reductase
59c3bitA_



not modelled 13.6 19 PDB header:transcription
Chain: A: PDB Molecule:fact complex subunit spt16;
PDBTitle: crystal structure of yeast spt16 n-terminal domain
60d2ez9a1



not modelled 13.5 16 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
61d1wjsa_



not modelled 13.3 13 Fold:SH3-like barrel
Superfamily:Tudor/PWWP/MBT
Family:MBT repeat
62c3ue3A_



not modelled 13.3 20 PDB header:transferase
Chain: A: PDB Molecule:septum formation, penicillin binding protein 3,
PDBTitle: crystal structure of acinetobacter baumanni pbp3
63c2op8A_



not modelled 13.2 14 PDB header:isomerase
Chain: A: PDB Molecule:probable tautomerase ywhb;
PDBTitle: crystal structure of ywhb- homologue of 4-oxalocrotonate tautomerase
64c2gzqA_



not modelled 13.0 12 PDB header:lipid binding protein
Chain: A: PDB Molecule:phosphatidylethanolamine-binding protein;
PDBTitle: phosphatidylethanolamine-binding protein from plasmodium vivax
65c1kyqC_



not modelled 12.9 28 PDB header:oxidoreductase, lyase
Chain: C: PDB Molecule:siroheme biosynthesis protein met8;
PDBTitle: met8p: a bifunctional nad-dependent dehydrogenase and2 ferrochelatase involved in siroheme synthesis.
66c1w7vD_



not modelled 12.9 24 PDB header:hydrolase
Chain: D: PDB Molecule:xaa-pro aminopeptidase;
PDBTitle: znmg substituted aminopeptidase p from e. coli
67c1alnA_



not modelled 12.6 19 PDB header:hydrolase
Chain: A: PDB Molecule:cytidine deaminase;
PDBTitle: crystal structure of cytidine deaminase complexed with 3-deazacytidine
68d1qlwa_



not modelled 12.5 27 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:A novel bacterial esterase
69c1hwjB_



not modelled 12.3 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:hmg-coa reductase;
PDBTitle: complex of the catalytic portion of human hmg-coa reductase2 with cerivastatin
70c3dclC_



not modelled 12.2 27 PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:tm1086;
PDBTitle: crystal structure of tm1086
71c3cd0B_



not modelled 12.2 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxy-3-methylglutaryl-coenzyme a reductase;
PDBTitle: thermodynamic and structure guided design of statin hmg-coa2 reductase inhibitors
72d1pvda1



not modelled 12.1 13 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
73d2ji7a1



not modelled 12.0 34 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
74c2l09A_



not modelled 12.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:asr4154 protein;
PDBTitle: solution nmr structure of protein asr4154 from nostoc sp. pcc71202 northeast structural genomics consortium target id nsr143
75d2bgra2



not modelled 11.8 9 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:DPP6 catalytic domain-like
76d1dosa_



not modelled 11.7 24 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
77c3cb5A_



not modelled 11.7 14 PDB header:transcription
Chain: A: PDB Molecule:fact complex subunit spt16;
PDBTitle: crystal structure of the s. pombe peptidase homology domain of fact2 complex subunit spt16 (form a)
78c3h04A_



not modelled 11.4 50 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50
79c2x4kB_



not modelled 11.3 25 PDB header:isomerase
Chain: B: PDB Molecule:4-oxalocrotonate tautomerase;
PDBTitle: crystal structure of sar1376, a putative 4-oxalocrotonate2 tautomerase from the methicillin-resistant staphylococcus3 aureus (mrsa)
80d1bjpa_



not modelled 11.0 23 Fold:Tautomerase/MIF
Superfamily:Tautomerase/MIF
Family:4-oxalocrotonate tautomerase-like
81c2g6pA_



not modelled 11.0 2 PDB header:hydrolase
Chain: A: PDB Molecule:methionine aminopeptidase 1;
PDBTitle: crystal structure of truncated (delta 1-89) human methionine2 aminopeptidase type 1 in complex with pyridyl pyrimidine derivative
82c2gz5A_



not modelled 11.0 2 PDB header:hydrolase
Chain: A: PDB Molecule:methionine aminopeptidase 1;
PDBTitle: human type 1 methionine aminopeptidase in complex with ovalicin at 1.12 ang
83d1alna1



not modelled 10.7 19 Fold:Cytidine deaminase-like
Superfamily:Cytidine deaminase-like
Family:Cytidine deaminase
84d1pjaa_



not modelled 10.6 42 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Thioesterases
85c1pjaA_



not modelled 10.6 42 PDB header:hydrolase
Chain: A: PDB Molecule:palmitoyl-protein thioesterase 2 precursor;
PDBTitle: the crystal structure of palmitoyl protein thioesterase-2 reveals the2 basis for divergent substrate specificities of the two lysosomal3 thioesterases (ppt1 and ppt2)
86d1snna_



not modelled 10.4 16 Fold:YrdC/RibB
Superfamily:YrdC/RibB
Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
87c3oc2A_



not modelled 10.3 23 PDB header:penicillin-binding protein
Chain: A: PDB Molecule:penicillin-binding protein 3;
PDBTitle: crystal structure of penicillin-binding protein 3 from pseudomonas2 aeruginosa
88d1oxwa_



not modelled 10.3 45 Fold:FabD/lysophospholipase-like
Superfamily:FabD/lysophospholipase-like
Family:Patatin
89d2pmra1



not modelled 10.2 14 Fold:immunoglobulin/albumin-binding domain-like
Superfamily:AF1782-like
Family:AF1782-like
90c3llcA_



not modelled 10.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:putative hydrolase;
PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution
91d1q6za1



not modelled 9.9 9 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
92c2jz5A_



not modelled 9.8 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein vpa0419;
PDBTitle: nmr solution structure of protein vpa0419 from vibrio2 parahaemolyticus. northeast structural genomics target3 vpr68
93c3dgsA_



not modelled 9.6 31 PDB header:viral protein
Chain: A: PDB Molecule:coat protein a;
PDBTitle: changing the determinants of protein stability from2 covalent to non-covalent interactions by in-vitro3 evolution: a structural and energetic analysis
94c1chmA_



not modelled 9.6 22 PDB header:creatinase
Chain: A: PDB Molecule:creatine amidinohydrolase;
PDBTitle: enzymatic mechanism of creatine amidinohydrolase as deduced2 from crystal structures
95c2kdvA_



not modelled 9.6 22 PDB header:hydrolase
Chain: A: PDB Molecule:rna pyrophosphohydrolase;
PDBTitle: solution structure of rna pyrophosphohydrolase rpph from2 escherichia coli
96d2nn6c2



not modelled 9.6 17 Fold:Ribonuclease PH domain 2-like
Superfamily:Ribonuclease PH domain 2-like
Family:Ribonuclease PH domain 2-like
97c3gy9A_



not modelled 9.6 21 PDB header:transferase
Chain: A: PDB Molecule:gcn5-related n-acetyltransferase;
PDBTitle: crystal structure of putative acetyltransferase (yp_001815201.1) from2 exiguobacterium sp. 255-15 at 1.52 a resolution
98c2z0rA_



not modelled 9.5 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative uncharacterized protein ttha0547;
PDBTitle: crystal structure of hypothetical protein ttha0547
99d1xkla_



not modelled 9.5 31 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hydroxynitrile lyase-like

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0