Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP76633
DateThu Jan 5 12:25:09 GMT 2012
Unique Job IDaed1d5fa81c478a2

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3cxtA_
Top template information
PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2
Confidence and coverage
Confidence:100.0% Coverage: 94%
246 residues ( 94% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEM
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Disorder  ?????????


















































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   .........70.........80.........90.........100.........110.........120
Sequence  IEKQGVEVDFMQVGITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDP
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   .........130.........140.........150.........160.........170.........180
Sequence  MIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAY
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?









?

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   .........190.........200.........210.........220.........230.........240
Sequence  CDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLA
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   .........250.........260.
Sequence  SPASNYVNGHLLVVDGGYLVR
Secondary structure 











SS confidence 




















Disorder 















?

??
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3cxt chain A

3D model

Region: 9 - 260
Aligned: 246
Modelled: 252
Confidence: 100.0%
Identity: 45%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2

Phyre2

PDB 3svt chain A

3D model

Region: 15 - 261
Aligned: 247
Modelled: 247
Confidence: 100.0%
Identity: 28%
PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans

Phyre2

PDB 1fmc chain A

3D model

Region: 9 - 261
Aligned: 251
Modelled: 253
Confidence: 100.0%
Identity: 33%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2ae2 chain A

3D model

Region: 13 - 261
Aligned: 249
Modelled: 249
Confidence: 100.0%
Identity: 30%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2zat chain C

3D model

Region: 15 - 261
Aligned: 247
Modelled: 247
Confidence: 100.0%
Identity: 28%
PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase/reductase sdr family member 4;
PDBTitle: crystal structure of a mammalian reductase

Phyre2

PDB 2q2q chain G

3D model

Region: 15 - 261
Aligned: 246
Modelled: 247
Confidence: 100.0%
Identity: 34%
PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida

Phyre2

PDB 1gee chain A

3D model

Region: 11 - 260
Aligned: 249
Modelled: 250
Confidence: 100.0%
Identity: 30%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3uf0 chain A

3D model

Region: 14 - 260
Aligned: 246
Modelled: 247
Confidence: 100.0%
Identity: 37%
PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a putative nad(p) dependent gluconate 5-2 dehydrogenase from beutenbergia cavernae(efi target efi-502044) with3 bound nadp (low occupancy)

Phyre2

PDB 3k31 chain B

3D model

Region: 9 - 260
Aligned: 244
Modelled: 252
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution

Phyre2

PDB 3rih chain B

3D model

Region: 13 - 261
Aligned: 247
Modelled: 249
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase or reductase;
PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus

Phyre2

PDB 3lf2 chain B

3D model

Region: 14 - 260
Aligned: 247
Modelled: 247
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain oxidoreductase q9hya2;
PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center

Phyre2

PDB 2c07 chain A domain 1

3D model

Region: 12 - 259
Aligned: 241
Modelled: 248
Confidence: 100.0%
Identity: 32%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2c07 chain A

3D model

Region: 12 - 259
Aligned: 241
Modelled: 248
Confidence: 100.0%
Identity: 32%
PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: oxoacyl-acp reductase of plasmodium falciparum

Phyre2

PDB 2pd4 chain A domain 1

3D model

Region: 15 - 261
Aligned: 247
Modelled: 247
Confidence: 100.0%
Identity: 16%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2cfc chain B

3D model

Region: 18 - 260
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 30%
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases

Phyre2

PDB 3gdf chain A

3D model

Region: 7 - 261
Aligned: 251
Modelled: 255
Confidence: 100.0%
Identity: 28%
PDB header:oxidoreductase
Chain: A: PDB Molecule:probable nadp-dependent mannitol dehydrogenase;
PDBTitle: crystal structure of the nadp-dependent mannitol dehydrogenase from2 cladosporium herbarum.

Phyre2

PDB 1ae1 chain A

3D model

Region: 14 - 260
Aligned: 238
Modelled: 247
Confidence: 100.0%
Identity: 31%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1w6u chain A

3D model

Region: 4 - 260
Aligned: 251
Modelled: 257
Confidence: 100.0%
Identity: 24%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1g0o chain A

3D model

Region: 3 - 260
Aligned: 257
Modelled: 258
Confidence: 100.0%
Identity: 25%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1ulu chain A

3D model

Region: 11 - 261
Aligned: 240
Modelled: 249
Confidence: 100.0%
Identity: 21%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2uvd chain E

3D model

Region: 16 - 260
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 36%
PDB header:oxidoreductase
Chain: E: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: the crystal structure of a 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis (ba3989)

Phyre2

PDB 1x1t chain A domain 1

3D model

Region: 16 - 261
Aligned: 232
Modelled: 232
Confidence: 100.0%
Identity: 36%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1vl8 chain A

3D model

Region: 14 - 260
Aligned: 247
Modelled: 247
Confidence: 100.0%
Identity: 38%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2wdz chain D

3D model

Region: 11 - 260
Aligned: 248
Modelled: 248
Confidence: 100.0%
Identity: 35%
PDB header:oxidoreductase
Chain: D: PDB Molecule:short-chain dehydrogenase/reductase;
PDBTitle: crystal structure of the short chain dehydrogenase2 galactitol-dehydrogenase (gatdh) of rhodobacter3 sphaeroides in complex with nad+ and 1,2-pentandiol

Phyre2
1

c3cxtA_
2

c3svtA_
3

d1fmca_
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d2ae2a_
5

c2zatC_
6

c2q2qG_
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d1geea_
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c3uf0A_
9

c3k31B_
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c3rihB_
11

c3lf2B_
12

d2c07a1
13

c2c07A_
14

d2pd4a1
15

c2cfcB_
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c3gdfA_
17

d1ae1a_
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d1w6ua_
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d1g0oa_
20

d1ulua_
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c2uvdE_
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d1x1ta1
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d1vl8a_
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c2wdzD_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3cxtA_



100.0 45 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2
2c3svtA_



100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans
3d1fmca_



100.0 33 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
4d2ae2a_



100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
5c2zatC_



100.0 28 PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase/reductase sdr family member 4;
PDBTitle: crystal structure of a mammalian reductase
6c2q2qG_



100.0 34 PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida
7d1geea_



100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
8c3uf0A_



100.0 37 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a putative nad(p) dependent gluconate 5-2 dehydrogenase from beutenbergia cavernae(efi target efi-502044) with3 bound nadp (low occupancy)
9c3k31B_



100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
10c3rihB_



100.0 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase or reductase;
PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus
11c3lf2B_



100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain oxidoreductase q9hya2;
PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center
12d2c07a1



100.0 32 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
13c2c07A_



100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: oxoacyl-acp reductase of plasmodium falciparum
14d2pd4a1



100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
15c2cfcB_



100.0 30 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases
16c3gdfA_



100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable nadp-dependent mannitol dehydrogenase;
PDBTitle: crystal structure of the nadp-dependent mannitol dehydrogenase from2 cladosporium herbarum.
17d1ae1a_



100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
18d1w6ua_



100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
19d1g0oa_



100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
20d1ulua_



100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
21c3ai3A_



not modelled 100.0 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph-sorbose reductase;
PDBTitle: the crystal structure of l-sorbose reductase from gluconobacter2 frateurii complexed with nadph and l-sorbose
22d1qsga_



not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
23c3grkE_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
24c2p68A_



not modelled 100.0 34 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5
25c3iccA_



not modelled 100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase;
PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution
26c3gvcB_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable short-chain type
PDBTitle: crystal structure of probable short-chain dehydrogenase-2 reductase from mycobacterium tuberculosis
27c3t7cC_



not modelled 100.0 30 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nad
28d1pr9a_



not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
29d1iy8a_



not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
30c3toxG_



not modelled 100.0 29 PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021
31c3ijrF_



not modelled 100.0 31 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+
32c3pk0B_



not modelled 100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of short-chain dehydrogenase/reductase sdr from2 mycobacterium smegmatis
33d1hdca_



not modelled 100.0 32 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
34c3oidA_



not modelled 100.0 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadph];
PDBTitle: crystal structure of enoyl-acp reductases iii (fabl) from b. subtilis2 (complex with nadp and tcl)
35d1k2wa_



not modelled 100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
36d1yxma1



not modelled 100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
37d1xhla_



not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
38d1zema1



not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
39c2uvdE_



100.0 36 PDB header:oxidoreductase
Chain: E: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: the crystal structure of a 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis (ba3989)
40d1q7ba_



not modelled 100.0 32 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
41c3ak4C_



not modelled 100.0 29 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh-dependent quinuclidinone reductase;
PDBTitle: crystal structure of nadh-dependent quinuclidinone reductase from2 agrobacterium tumefaciens
42c3emkA_



not modelled 100.0 33 PDB header:oxidoreductase
Chain: A: PDB Molecule:glucose/ribitol dehydrogenase;
PDBTitle: 2.5a crystal structure of glucose/ribitol dehydrogenase2 from brucella melitensis
43d1h5qa_



not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
44d2rhca1



not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
45c3r3sD_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase;
PDBTitle: structure of the ygha oxidoreductase from salmonella enterica
46c3itdA_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:17beta-hydroxysteroid dehydrogenase;
PDBTitle: crystal structure of an inactive 17beta-hydroxysteroid dehydrogenase2 (y167f mutated form) from fungus cochliobolus lunatus
47c1w4zA_



not modelled 100.0 30 PDB header:antibiotic biosynthesis
Chain: A: PDB Molecule:ketoacyl reductase;
PDBTitle: structure of actinorhodin polyketide (actiii) reductase
48c3gr6A_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of the staphylococcus aureus enoyl-acyl2 carrier protein reductase (fabi) in complex with nadp and3 triclosan
49c3imfA_



not modelled 100.0 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:short chain dehydrogenase;
PDBTitle: 1.99 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor'
50c2b4qB_



not modelled 100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:rhamnolipids biosynthesis 3-oxoacyl-[acyl-
PDBTitle: pseudomonas aeruginosa rhlg/nadp active-site complex
51c3gk3D_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: D: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetoacetyl-coa reductase from2 burkholderia pseudomallei 1710b
52c3v2gA_



not modelled 100.0 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of a dehydrogenase/reductase from sinorhizobium2 meliloti 1021
53d1ja9a_



not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
54c2qioA_



not modelled 100.0 19 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
55c3ek2D_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b
56d1zk4a1



not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
57c3ftpD_



not modelled 100.0 33 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein)2 reductase from burkholderia pseudomallei at 2.05 a3 resolution
58d2ew8a1



not modelled 100.0 34 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
59c3lylB_



not modelled 100.0 32 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis
60c3ezlA_



not modelled 100.0 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetyacetyl-coa reductase from2 burkholderia pseudomallei 1710b
61d1xkqa_



not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
62c2p91A_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of enoyl-[acyl-carrier-protein] reductase (nadh)2 from aquifex aeolicus vf5
63c2z1nA_



not modelled 100.0 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure of ape0912 from aeropyrum pernix k1
64d2bgka1



not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
65c2dteB_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: B: PDB Molecule:glucose 1-dehydrogenase related protein;
PDBTitle: structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt)2 in complex with nadh
66c3nugA_



not modelled 100.0 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti
67d1nffa_



not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
68d1x1ta1



100.0 36 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
69c3afnC_



not modelled 100.0 26 PDB header:oxidoreductase
Chain: C: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of aldose reductase a1-r complexed with nadp
70c3uveC_



not modelled 100.0 26 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase ((+)-trans-carveol dehydrogenase);
PDBTitle: crystal structure of carveol dehydrogenase ((+)-trans-carveol2 dehydrogenase) from mycobacterium avium
71c2jjyD_



not modelled 100.0 15 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of francisella tularensis enoyl reductase2 (ftfabi) with bound nad
72c3sjuA_



not modelled 100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:keto reductase;
PDBTitle: hedamycin polyketide ketoreductase bound to nadph
73c3pgxB_



not modelled 100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of a putative carveol dehydrogenase from2 mycobacterium paratuberculosis bound to nicotinamide adenine3 dinucleotide
74c3oecA_



not modelled 100.0 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:carveol dehydrogenase (mytha.01326.c, a0r518 homolog);
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium2 thermoresistibile
75c3r1iB_



not modelled 100.0 31 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: crystal structure of a short-chain type dehydrogenase/reductase from2 mycobacterium marinum
76d1vl8a_



100.0 38 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
77c3bmrA_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:pteridine reductase;
PDBTitle: structure of pteridine reductase 1 (ptr1) from trypanosoma2 brucei in ternary complex with cofactor (nadp+) and3 inhibitor (compound ax6)
78d1gega_



not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
79d1ydea1



not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
80c2et6A_



not modelled 100.0 29 PDB header:oxidoreductase
Chain: A: PDB Molecule:(3r)-hydroxyacyl-coa dehydrogenase;
PDBTitle: (3r)-hydroxyacyl-coa dehydrogenase domain of candida tropicalis2 peroxisomal multifunctional enzyme type 2
81c3o38D_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: D: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 smegmatis
82c3ctmH_



not modelled 100.0 31 PDB header:oxidoreductase
Chain: H: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of a carbonyl reductase from candida2 parapsilosis with anti-prelog stereo-specificity
83c3osuA_



not modelled 100.0 33 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of the 3-oxoacyl-acyl carrier protein reductase,2 fabg, from staphylococcus aureus
84d1edoa_



not modelled 100.0 33 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
85d2d1ya1



not modelled 100.0 33 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
86c2pd6D_



not modelled 100.0 22 PDB header:oxidoreductase
Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8;
PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8
87d1bdba_



not modelled 100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
88c3uxyC_



not modelled 100.0 27 PDB header:oxidoreductase
Chain: C: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: the crystal structure of short chain dehydrogenase from rhodobacter2 sphaeroides
89d1o5ia_



not modelled 100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
90d1ulsa_



not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
91c2wdzD_



100.0 35 PDB header:oxidoreductase
Chain: D: PDB Molecule:short-chain dehydrogenase/reductase;
PDBTitle: crystal structure of the short chain dehydrogenase2 galactitol-dehydrogenase (gatdh) of rhodobacter3 sphaeroides in complex with nad+ and 1,2-pentandiol
92c3llsB_



not modelled 100.0 31 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 mycobacterium tuberculosis
93d1e6wa_



not modelled 100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
94c3ppiA_



not modelled 100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium
95d1cyda_



not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
96d1hxha_



not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
97c3i4fD_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: structure of putative 3-oxoacyl-reductase from bacillus thuringiensis
98c2ph3B_



not modelled 100.0 32 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-[acyl carrier protein] reductase;
PDBTitle: crystal structure of 3-oxoacyl-[acyl carrier protein] reductase2 ttha0415 from thermus thermophilus
99c3rkuC_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: C: PDB Molecule:oxidoreductase ymr226c;
PDBTitle: substrate fingerprint and the structure of nadp+ dependent serine2 dehydrogenase from saccharomyces cerevisiae complexed with nadp+
100c3v2hB_



not modelled 100.0 33 PDB header:oxidoreductase
Chain: B: PDB Molecule:d-beta-hydroxybutyrate dehydrogenase;
PDBTitle: the crystal structure of d-beta-hydroxybutyrate dehydrogenase from2 sinorhizobium meliloti
101c3sc4A_



not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:short chain dehydrogenase (a0qtm2 homolog);
PDBTitle: crystal structure of a short chain dehydrogenase (a0qtm2 homolog)2 mycobacterium thermoresistibile
102c3e03C_



not modelled 100.0 23 PDB header:oxidoreductase
Chain: C: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a putative dehydrogenase from2 xanthomonas campestris
103c3omlA_



not modelled 100.0 26 PDB header:oxidoreductase, hydrolase
Chain: A: PDB Molecule:peroxisomal multifunctional enzyme type 2, cg3415;
PDBTitle: structure of full-length peroxisomal multifunctional enzyme type 22 from drosophila melanogaster
104c3n74A_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 brucella melitensis
105c3f9iB_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase2 rickettsia prowazekii
106d1spxa_



not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
107c3un1D_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: D: PDB Molecule:probable oxidoreductase;
PDBTitle: crystal structure of an oxidoreductase from sinorhizobium meliloti2 1021
108d1uaya_



not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
109d2a4ka1



not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
110c3sx2F_



not modelled 100.0 24 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative 3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of a putative 3-ketoacyl-(acyl-carrier-protein)2 reductase from mycobacterium paratuberculosis in complex with nad
111c3pxxE_



not modelled 100.0 26 PDB header:oxidoreductase
Chain: E: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nicotinamide adenine dinucleotide
112d1mxha_



not modelled 100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
113c3s55F_



not modelled 100.0 30 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative short-chain dehydrogenase/reductase;
PDBTitle: crystal structure of a putative short-chain dehydrogenase/reductase2 from mycobacterium abscessus bound to nad
114d1p33a_



not modelled 100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
115c3qljB_



not modelled 100.0 30 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 avium
116c3ksuA_



not modelled 100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-acyl carrier protein reductase;
PDBTitle: crystal structure of short-chain dehydrogenase from2 oenococcus oeni psu-1
117c3diiB_



not modelled 100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a carbohydrate specific scor enzyme2 from clostridium thermocellum, ligand-free form
118c2fwmX_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: X: PDB Molecule:2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase;
PDBTitle: crystal structure of e. coli enta, a 2,3-dihydrodihydroxy benzoate2 dehydrogenase
119c2qhxB_



not modelled 100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:pteridine reductase 1;
PDBTitle: structure of pteridine reductase from leishmania major2 complexed with a ligand
120c1zbqB_



not modelled 100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:17-beta-hydroxysteroid dehydrogenase 4;
PDBTitle: crystal structure of human 17-beta-hydroxysteroid dehydrogenase type 42 in complex with nad

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0