Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	L	H	N	L	T	R	F	P	R	L	E	F	I	G	A	P	T	P	L	E	Y	L	P	R	F	S	D	Y	L	G	R	E	I	F	I	K	R	D	D	V	T	P	M	A	M	G	G	N	K	L	R	K	L	E	F	L	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?						?																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	A	L	R	E	G	A	D	T	L	I	T	A	G	A	I	Q	S	N	H	V	R	Q	T	A	A	V	A	A	K	L	G	L	H	C	V	A	L	L	E	N	P	I	G	T	T	A	E	N	Y	L	T	N	G	N	R	L	L	L	D
Secondary structure
SS confidence
Disorder																																														?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	F	N	T	Q	I	E	M	C	D	A	L	T	D	P	N	A	Q	L	E	E	L	A	T	R	V	E	A	Q	G	F	R	P	Y	V	I	P	V	G	G	S	N	A	L	G	A	L	G	Y	V	E	S	A	L	E	I	A	Q	Q	C
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	G	A	V	N	I	S	S	V	V	V	A	S	G	S	A	G	T	H	A	G	L	A	V	G	L	E	H	L	M	P	E	S	E	L	I	G	V	T	V	S	R	S	V	A	D	Q	L	P	K	V	V	N	L	Q	Q	A	I	A	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	L	E	L	T	A	S	A	E	I	L	L	W	D	D	Y	F	A	P	G	Y	G	V	P	N	D	E	G	M	E	A	V	K	L	L	A	R	L	E	G	I	L	L	D	P	V	Y	T	G	K	A	M	A	G	L	I	D	G	I	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.
Sequence		Q	K	R	F	K	D	E	G	P	I	L	F	I	H	T	G	G	A	P	A	L	F	A	Y	H	P	H	V
Secondary structure
SS confidence
Disorder			?	?																			?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1j0a chain A Region: 4 - 327 Aligned: 312 Modelled: 324 Confidence: 100.0% Identity: 40% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 1f2d chain A Region: 6 - 327 Aligned: 322 Modelled: 322 Confidence: 100.0% Identity: 32% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 1tyz chain A Region: 5 - 326 Aligned: 317 Modelled: 322 Confidence: 100.0% Identity: 38% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 1tdj chain A Region: 11 - 321 Aligned: 290 Modelled: 309 Confidence: 100.0% Identity: 22% PDB header:allostery Chain: A: PDB Molecule:biosynthetic threonine deaminase; PDBTitle: threonine deaminase (biosynthetic) from e. coli Phyre2 PDB 3l6c chain A Region: 1 - 321 Aligned: 300 Modelled: 317 Confidence: 100.0% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:serine racemase; PDBTitle: x-ray crystal structure of rat serine racemase in complex with2 malonate a potent inhibitor Phyre2 PDB 3iau chain A Region: 11 - 326 Aligned: 294 Modelled: 303 Confidence: 100.0% Identity: 19% PDB header:lyase Chain: A: PDB Molecule:threonine deaminase; PDBTitle: the structure of the processed form of threonine deaminase isoform 22 from solanum lycopersicum Phyre2 PDB 3pc3 chain A Region: 2 - 321 Aligned: 302 Modelled: 312 Confidence: 100.0% Identity: 19% PDB header:lyase Chain: A: PDB Molecule:cg1753, isoform a; PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate Phyre2 PDB 1v71 chain A domain 1 Region: 3 - 326 Aligned: 301 Modelled: 314 Confidence: 100.0% Identity: 18% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 1z7w chain A domain 1 Region: 9 - 321 Aligned: 294 Modelled: 305 Confidence: 100.0% Identity: 20% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 2d1f chain A Region: 3 - 317 Aligned: 295 Modelled: 302 Confidence: 100.0% Identity: 21% PDB header:lyase Chain: A: PDB Molecule:threonine synthase; PDBTitle: structure of mycobacterium tuberculosis threonine synthase Phyre2 PDB 1jbq chain A Region: 9 - 327 Aligned: 297 Modelled: 309 Confidence: 100.0% Identity: 19% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 1jbq chain D Region: 9 - 327 Aligned: 297 Modelled: 308 Confidence: 100.0% Identity: 19% PDB header:lyase Chain: D: PDB Molecule:cystathionine beta-synthase; PDBTitle: structure of human cystathionine beta-synthase: a unique pyridoxal 5'-2 phosphate dependent hemeprotein Phyre2 PDB 1pwh chain A Region: 15 - 317 Aligned: 284 Modelled: 295 Confidence: 100.0% Identity: 20% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 2gn0 chain A Region: 1 - 326 Aligned: 304 Modelled: 311 Confidence: 100.0% Identity: 17% PDB header:lyase Chain: A: PDB Molecule:threonine dehydratase catabolic; PDBTitle: crystal structure of dimeric biodegradative threonine deaminase (tdcb)2 from salmonella typhimurium at 1.7 a resolution (triclinic form with3 one complete subunit built in alternate conformation) Phyre2 PDB 1tdj chain A domain 1 Region: 11 - 325 Aligned: 294 Modelled: 312 Confidence: 100.0% Identity: 22% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 1wkv chain A domain 1 Region: 2 - 321 Aligned: 288 Modelled: 320 Confidence: 100.0% Identity: 20% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 1p5j chain A Region: 15 - 317 Aligned: 284 Modelled: 291 Confidence: 100.0% Identity: 18% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 1p5j chain A Region: 15 - 317 Aligned: 284 Modelled: 291 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: A: PDB Molecule:l-serine dehydratase; PDBTitle: crystal structure analysis of human serine dehydratase Phyre2 PDB 2pqm chain A Region: 9 - 321 Aligned: 293 Modelled: 305 Confidence: 100.0% Identity: 15% PDB header:lyase Chain: A: PDB Molecule:cysteine synthase; PDBTitle: crystal structure of cysteine synthase (oass) from entamoeba2 histolytica at 1.86 a resolution Phyre2 PDB 1ve1 chain A domain 1 Region: 11 - 323 Aligned: 289 Modelled: 300 Confidence: 100.0% Identity: 20% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 1 d1j0aa_ 2 d1f2da_ 3 d1tyza_ 4 c1tdjA_ 5 c3l6cA_ 6 c3iauA_ 7 c3pc3A_ 8 d1v71a1 9 d1z7wa1 10 c2d1fA_ 11 d1jbqa_ 12 c1jbqD_ 13 d1pwha_ 14 c2gn0A_ 15 d1tdja1 16 d1wkva1 17 d1p5ja_ 18 c1p5jA_ 19 c2pqmA_ 20 d1ve1a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1j0aa_ 100.0 40 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 2 d1f2da_ 100.0 32 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 3 d1tyza_ 100.0 38 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 4 c1tdjA_ 100.0 22 PDB header:allostery Chain: A: PDB Molecule:biosynthetic threonine deaminase; PDBTitle: threonine deaminase (biosynthetic) from e. coli 5 c3l6cA_ 100.0 18 PDB header:isomerase Chain: A: PDB Molecule:serine racemase; PDBTitle: x-ray crystal structure of rat serine racemase in complex with2 malonate a potent inhibitor 6 c3iauA_ 100.0 19 PDB header:lyase Chain: A: PDB Molecule:threonine deaminase; PDBTitle: the structure of the processed form of threonine deaminase isoform 22 from solanum lycopersicum 7 c3pc3A_ 100.0 19 PDB header:lyase Chain: A: PDB Molecule:cg1753, isoform a; PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate 8 d1v71a1 100.0 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 9 d1z7wa1 100.0 20 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 10 c2d1fA_ 100.0 21 PDB header:lyase Chain: A: PDB Molecule:threonine synthase; PDBTitle: structure of mycobacterium tuberculosis threonine synthase 11 d1jbqa_ 100.0 19 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 12 c1jbqD_ 100.0 19 PDB header:lyase Chain: D: PDB Molecule:cystathionine beta-synthase; PDBTitle: structure of human cystathionine beta-synthase: a unique pyridoxal 5'-2 phosphate dependent hemeprotein 13 d1pwha_ 100.0 20 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 14 c2gn0A_ 100.0 17 PDB header:lyase Chain: A: PDB Molecule:threonine dehydratase catabolic; PDBTitle: crystal structure of dimeric biodegradative threonine deaminase (tdcb)2 from salmonella typhimurium at 1.7 a resolution (triclinic form with3 one complete subunit built in alternate conformation) 15 d1tdja1 100.0 22 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 16 d1wkva1 100.0 20 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 17 d1p5ja_ 100.0 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 18 c1p5jA_ 100.0 18 PDB header:lyase Chain: A: PDB Molecule:l-serine dehydratase; PDBTitle: crystal structure analysis of human serine dehydratase 19 c2pqmA_ 100.0 15 PDB header:lyase Chain: A: PDB Molecule:cysteine synthase; PDBTitle: crystal structure of cysteine synthase (oass) from entamoeba2 histolytica at 1.86 a resolution 20 d1ve1a1 100.0 20 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 21 d1v7ca_ not modelled 100.0 20 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 22 d1ve5a1 not modelled 100.0 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 23 c2zsjB_ not modelled 100.0 20 PDB header:lyase Chain: B: PDB Molecule:threonine synthase; PDBTitle: crystal structure of threonine synthase from aquifex aeolicus vf5 24 c3dwgA_ not modelled 100.0 18 PDB header:transferase Chain: A: PDB Molecule:cysteine synthase b; PDBTitle: crystal structure of a sulfur carrier protein complex found in the2 cysteine biosynthetic pathway of mycobacterium tuberculosis 25 d2bhsa1 not modelled 100.0 19 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 26 c1x1qA_ not modelled 100.0 22 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: crystal structure of tryptophan synthase beta chain from thermus2 thermophilus hb8 27 c2rkbE_ not modelled 100.0 20 PDB header:lyase Chain: E: PDB Molecule:serine dehydratase-like; PDBTitle: serine dehydratase like-1 from human cancer cells 28 c3r0zA_ not modelled 100.0 18 PDB header:lyase Chain: A: PDB Molecule:d-serine dehydratase; PDBTitle: crystal structure of apo d-serine deaminase from salmonella2 typhimurium 29 c2q3bA_ not modelled 100.0 19 PDB header:transferase Chain: A: PDB Molecule:cysteine synthase a; PDBTitle: 1.8 a resolution crystal structure of o-acetylserine sulfhydrylase2 (oass) holoenzyme from mycobacterium tuberculosis 30 d1qopb_ not modelled 100.0 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 31 d1fcja_ not modelled 100.0 15 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 32 d1o58a_ not modelled 100.0 17 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 33 d1v8za1 not modelled 100.0 20 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 34 d1y7la1 not modelled 100.0 16 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 35 c2eguA_ not modelled 100.0 21 PDB header:transferase Chain: A: PDB Molecule:cysteine synthase; PDBTitle: crystal structure of o-acetylserine sulfhydrase from geobacillus2 kaustophilus hta426 36 d1e5xa_ not modelled 100.0 17 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 37 c2o2jA_ not modelled 100.0 23 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: mycobacterium tuberculosis tryptophan synthase beta chain2 dimer (apoform) 38 c3v7nA_ not modelled 100.0 15 PDB header:lyase Chain: A: PDB Molecule:threonine synthase; PDBTitle: crystal structure of threonine synthase (thrc) from from burkholderia2 thailandensis 39 d1vb3a1 not modelled 100.0 17 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 40 d1kl7a_ not modelled 99.8 15 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 41 d1hyua1 not modelled 79.5 15 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 42 d1fl2a1 not modelled 76.9 15 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 43 d1trba1 not modelled 74.7 23 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 44 c3ot4F_ not modelled 65.9 19 PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf 45 d1vdca1 not modelled 65.5 21 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 46 d1seza1 not modelled 64.2 17 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 47 c1djnB_ not modelled 61.8 18 PDB header:oxidoreductase Chain: B: PDB Molecule:trimethylamine dehydrogenase; PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1) 48 d1j8yf2 not modelled 61.1 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 49 d3lada1 not modelled 61.0 30 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 50 d2iida1 not modelled 60.2 22 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 51 c3gmbB_ not modelled 59.3 14 PDB header:oxidoreductase Chain: B: PDB Molecule:2-methyl-3-hydroxypyridine-5-carboxylic acid PDBTitle: crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic2 acid oxygenase 52 d1reoa1 not modelled 58.9 19 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 53 d1o8ca2 not modelled 58.6 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 54 d1ebda1 not modelled 58.5 26 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 55 c2ywlA_ not modelled 58.4 26 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin reductase related protein; PDBTitle: crystal structure of thioredoxin reductase-related protein ttha03702 from thermus thermophilus hb8 56 c2e1mA_ not modelled 58.1 19 PDB header:oxidoreductase Chain: A: PDB Molecule:l-glutamate oxidase; PDBTitle: crystal structure of l-glutamate oxidase from streptomyces sp. x-119-6 57 d1dxla1 not modelled 57.9 22 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 58 d2i0za1 not modelled 57.8 26 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:HI0933 N-terminal domain-like 59 c3r2jC_ not modelled 57.0 18 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate 60 c3c7cB_ not modelled 56.7 16 PDB header:oxidoreductase Chain: B: PDB Molecule:octopine dehydrogenase; PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine) 61 d1xpma2 not modelled 55.8 23 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 62 c1qzwC_ not modelled 54.6 14 PDB header:signaling protein/rna Chain: C: PDB Molecule:signal recognition 54 kda protein; PDBTitle: crystal structure of the complete core of archaeal srp and2 implications for inter-domain communication 63 c3allA_ not modelled 54.4 13 PDB header:oxidoreductase Chain: A: PDB Molecule:2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase; PDBTitle: crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid2 oxygenase, mutant y270a 64 d1lvla1 not modelled 54.3 26 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 65 d1ryia1 not modelled 53.0 15 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 66 d1wd5a_ not modelled 53.0 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 67 d1ojta1 not modelled 52.2 22 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 68 c3dm5A_ not modelled 52.1 17 PDB header:rna binding protein, transport protein Chain: A: PDB Molecule:signal recognition 54 kda protein; PDBTitle: structures of srp54 and srp19, the two proteins assembling2 the ribonucleic core of the signal recognition particle3 from the archaeon pyrococcus furiosus. 69 d1pvva2 not modelled 51.5 16 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 70 c1j8yF_ not modelled 51.3 12 PDB header:signaling protein Chain: F: PDB Molecule:signal recognition 54 kda protein; PDBTitle: signal recognition particle conserved gtpase domain from a.2 ambivalens t112a mutant 71 d1t57a_ not modelled 50.1 20 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 72 c3on5B_ not modelled 50.1 24 PDB header:oxidoreductase Chain: B: PDB Molecule:bh1974 protein; PDBTitle: crystal structure of a xanthine dehydrogenase (bh1974) from bacillus2 halodurans at 2.80 a resolution 73 d1u6ea2 not modelled 49.8 15 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 74 c3iupB_ not modelled 49.7 16 PDB header:oxidoreductase Chain: B: PDB Molecule:putative nadph:quinone oxidoreductase; PDBTitle: crystal structure of putative nadph:quinone oxidoreductase2 (yp_296108.1) from ralstonia eutropha jmp134 at 1.70 a resolution 75 c3h75A_ not modelled 49.5 11 PDB header:sugar binding protein Chain: A: PDB Molecule:periplasmic sugar-binding domain protein; PDBTitle: crystal structure of a periplasmic sugar-binding protein from the2 pseudomonas fluorescens 76 c3nrnA_ not modelled 48.9 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pf1083; PDBTitle: crystal structure of pf1083 protein from pyrococcus furiosus,2 northeast structural genomics consortium target pfr223 77 c3jskN_ not modelled 48.8 8 PDB header:biosynthetic protein Chain: N: PDB Molecule:cypbp37 protein; PDBTitle: thiazole synthase from neurospora crassa 78 c2vdcI_ not modelled 48.1 14 PDB header:oxidoreductase Chain: I: PDB Molecule:glutamate synthase [nadph] small chain; PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications. 79 c1sezA_ not modelled 48.0 20 PDB header:oxidoreductase Chain: A: PDB Molecule:protoporphyrinogen oxidase, mitochondrial; PDBTitle: crystal structure of protoporphyrinogen ix oxidase 80 d2h00a1 not modelled 47.8 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Methyltransferase 10 domain 81 d1lpfa1 not modelled 47.8 30 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 82 d2gf3a1 not modelled 47.4 22 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 83 c1vi2B_ not modelled 47.3 12 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase 2; PDBTitle: crystal structure of shikimate-5-dehydrogenase with nad 84 c3kljA_ not modelled 47.2 13 PDB header:oxidoreductase Chain: A: PDB Molecule:nad(fad)-dependent dehydrogenase, nirb-family (n-terminal PDBTitle: crystal structure of nadh:rubredoxin oxidoreductase from clostridium2 acetobutylicum 85 d1o8bb1 not modelled 47.2 17 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:D-ribose-5-phosphate isomerase (RpiA), catalytic domain 86 d1otha2 not modelled 46.9 22 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 87 d1neka2 not modelled 46.6 22 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain 88 c3fbsB_ not modelled 46.2 15 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: the crystal structure of the oxidoreductase from agrobacterium2 tumefaciens 89 d2cula1 not modelled 46.2 26 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:GidA-like 90 c3k30B_ not modelled 46.1 19 PDB header:oxidoreductase Chain: B: PDB Molecule:histamine dehydrogenase; PDBTitle: histamine dehydrogenase from nocardiodes simplex 91 c3ma0A_ not modelled 46.0 11 PDB header:sugar binding protein Chain: A: PDB Molecule:d-xylose-binding periplasmic protein; PDBTitle: closed liganded crystal structure of xylose binding protein from2 escherichia coli 92 c3f8rD_ not modelled 45.9 19 PDB header:oxidoreductase Chain: D: PDB Molecule:thioredoxin reductase (trxb-3); PDBTitle: crystal structure of sulfolobus solfataricus thioredoxin2 reductase b3 in complex with two nadp molecules 93 d1k0ia1 not modelled 44.2 20 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 94 c3muxB_ not modelled 44.0 17 PDB header:lyase Chain: B: PDB Molecule:putative 4-hydroxy-2-oxoglutarate aldolase; PDBTitle: the crystal structure of a putative 4-hydroxy-2-oxoglutarate aldolase2 from bacillus anthracis to 1.45a 95 d1v59a1 not modelled 44.0 22 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 96 c2j37W_ not modelled 43.8 13 PDB header:ribosome Chain: W: PDB Molecule:signal recognition particle 54 kda protein PDBTitle: model of mammalian srp bound to 80s rncs 97 c1txtB_ not modelled 43.8 23 PDB header:lyase Chain: B: PDB Molecule:3-hydroxy-3-methylglutaryl-coa synthase; PDBTitle: staphylococcus aureus 3-hydroxy-3-methylglutaryl-coa2 synthase 98 d1hnja2 not modelled 42.7 20 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 99 c3v76A_ not modelled 42.7 21 PDB header:flavoprotein Chain: A: PDB Molecule:flavoprotein; PDBTitle: the crystal structure of a flavoprotein from sinorhizobium meliloti 100 c1f8sA_ not modelled 42.7 22 PDB header:oxidoreductase Chain: A: PDB Molecule:l-amino acid oxidase; PDBTitle: crystal structure of l-amino acid oxidase from calloselasma2 rhodostoma, complexed with three molecules of o-aminobenzoate. 101 c3g05B_ not modelled 42.3 26 PDB header:rna binding protein Chain: B: PDB Molecule:trna uridine 5-carboxymethylaminomethyl modification enzyme PDBTitle: crystal structure of n-terminal domain (2-550) of e.coli mnmg 102 c3cgvA_ not modelled 42.2 26 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:geranylgeranyl reductase related protein; PDBTitle: crystal structure of geranylgeranyl bacteriochlorophyll reductase-like2 fixc homolog (np_393992.1) from thermoplasma acidophilum at 1.60 a3 resolution 103 d1gesa1 not modelled 42.1 22 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 104 c2gqfA_ not modelled 42.0 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein hi0933; PDBTitle: crystal structure of flavoprotein hi0933 from haemophilus influenzae2 rd 105 c2xdoC_ not modelled 41.8 10 PDB header:oxidoreductase Chain: C: PDB Molecule:tetx2 protein; PDBTitle: structure of the tetracycline degrading monooxygenase tetx2 from2 bacteroides thetaiotaomicron 106 c1ps9A_ not modelled 41.5 22 PDB header:oxidoreductase Chain: A: PDB Molecule:2,4-dienoyl-coa reductase; PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase 107 d2bs2a2 not modelled 41.5 19 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain 108 d1djqa3 not modelled 41.4 19 Fold:Nucleotide-binding domain Superfamily:Nucleotide-binding domain Family:N-terminal domain of adrenodoxin reductase-like 109 c2bryA_ not modelled 41.4 24 PDB header:transport Chain: A: PDB Molecule:nedd9 interacting protein with calponin homology PDBTitle: crystal structure of the native monooxygenase domain of2 mical at 1.45 a resolution 110 c1mzjB_ not modelled 41.2 21 PDB header:transferase Chain: B: PDB Molecule:beta-ketoacylsynthase iii; PDBTitle: crystal structure of the priming beta-ketosynthase from the2 r1128 polyketide biosynthetic pathway 111 d2voua1 not modelled 41.2 17 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 112 d1mzja2 not modelled 41.0 19 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 113 d1h6va1 not modelled 40.4 30 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 114 c2rghA_ not modelled 40.1 24 PDB header:oxidoreductase Chain: A: PDB Molecule:alpha-glycerophosphate oxidase; PDBTitle: structure of alpha-glycerophosphate oxidase from2 streptococcus sp.: a template for the mitochondrial alpha-3 glycerophosphate dehydrogenase 115 d1onfa1 not modelled 39.9 22 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 116 d1bg6a2 not modelled 39.9 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 117 c1yvvB_ not modelled 39.9 11 PDB header:oxidoreductase Chain: B: PDB Molecule:amine oxidase, flavin-containing; PDBTitle: x-ray structurure of p. syringae q888a4 oxidoreductase at2 resolution 2.5a. northeast structural genomics consortium3 target psr10. 118 d1mv8a2 not modelled 39.9 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 119 d2g5ca2 not modelled 39.6 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 120 c2i0zA_ not modelled 39.6 26 PDB header:oxidoreductase Chain: A: PDB Molecule:nad(fad)-utilizing dehydrogenases; PDBTitle: crystal structure of a fad binding protein from bacillus2 cereus, a putative nad(fad)-utilizing dehydrogenases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0