Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP77376
DateThu Jan 5 12:28:19 GMT 2012
Unique Job IDa9486a9bed1c22cf

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3kuxA_
Top template information
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: structure of the ypo2259 putative oxidoreductase from yersinia pestis
Confidence and coverage
Confidence:100.0% Coverage: 99%
342 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSDNIRVGLIGYGYASKTFHAPLIAGTPGQELAVISSSDETKVKADWPTVTVVSEPKHLF
Secondary structure 



















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Disorder  ????























































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   .........70.........80.........90.........100.........110.........120
Sequence  NDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLSQARELDALAKSLGRVLSV
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   .........130.........140.........150.........160.........170.........180
Sequence  FHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVRDRWREQGGPGSGIWYDLAPH
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Disorder 



































?
???


















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   .........190.........200.........210.........220.........230.........240
Sequence  LLDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSYPQRRVILHGTMLAAAESARYIV
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   .........250.........260.........270.........280.........290.........300
Sequence  HGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRDGVLTRVEGEERVEETLLTVPGNYP
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Disorder 






















?
???































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   .........310.........320.........330.........340......
Sequence  AYYAAIRDALNGDGENPVPASQAIQVMELIELGIESAKHRATLCLA
Secondary structure 












SS confidence 













































Disorder 






































???

??
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3kux chain A

3D model

Region: 2 - 346
Aligned: 342
Modelled: 345
Confidence: 100.0%
Identity: 70%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: structure of the ypo2259 putative oxidoreductase from yersinia pestis

Phyre2

PDB 3gfg chain B

3D model

Region: 1 - 345
Aligned: 344
Modelled: 345
Confidence: 100.0%
Identity: 38%
PDB header:oxidoreductase
Chain: B: PDB Molecule:uncharacterized oxidoreductase yvaa;
PDBTitle: structure of putative oxidoreductase yvaa from bacillus subtilis in2 triclinic form

Phyre2

PDB 3e18 chain A

3D model

Region: 1 - 344
Aligned: 341
Modelled: 343
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of nad-binding protein from listeria innocua

Phyre2

PDB 3fhl chain C

3D model

Region: 3 - 345
Aligned: 332
Modelled: 343
Confidence: 100.0%
Identity: 40%
PDB header:oxidoreductase
Chain: C: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from bacteroides2 fragilis nctc 9343

Phyre2

PDB 3e82 chain A

3D model

Region: 4 - 345
Aligned: 328
Modelled: 342
Confidence: 100.0%
Identity: 49%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from2 klebsiella pneumoniae

Phyre2

PDB 3f4l chain F

3D model

Region: 5 - 346
Aligned: 338
Modelled: 342
Confidence: 100.0%
Identity: 37%
PDB header:oxidoreductase
Chain: F: PDB Molecule:putative oxidoreductase yhhx;
PDBTitle: crystal structure of a probable oxidoreductase yhhx in2 triclinic form. northeast structural genomics target er647

Phyre2

PDB 1h6d chain L

3D model

Region: 1 - 345
Aligned: 330
Modelled: 330
Confidence: 100.0%
Identity: 17%
PDB header:protein translocation
Chain: L: PDB Molecule:precursor form of glucose-fructose
PDBTitle: oxidized precursor form of glucose-fructose oxidoreductase2 from zymomonas mobilis complexed with glycerol

Phyre2

PDB 1ofg chain F

3D model

Region: 1 - 345
Aligned: 330
Modelled: 330
Confidence: 100.0%
Identity: 17%
PDB header:oxidoreductase
Chain: F: PDB Molecule:glucose-fructose oxidoreductase;
PDBTitle: glucose-fructose oxidoreductase

Phyre2

PDB 3oqb chain F

3D model

Region: 4 - 346
Aligned: 336
Modelled: 343
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase from bradyrhizobium2 japonicum usda 110

Phyre2

PDB 3fd8 chain A

3D model

Region: 4 - 345
Aligned: 338
Modelled: 338
Confidence: 100.0%
Identity: 33%
PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis

Phyre2

PDB 3db2 chain C

3D model

Region: 3 - 345
Aligned: 334
Modelled: 343
Confidence: 100.0%
Identity: 17%
PDB header:oxidoreductase
Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase;
PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution

Phyre2

PDB 2glx chain D

3D model

Region: 6 - 346
Aligned: 321
Modelled: 322
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: D: PDB Molecule:1,5-anhydro-d-fructose reductase;
PDBTitle: crystal structure analysis of bacterial 1,5-af reductase

Phyre2

PDB 3moi chain A

3D model

Region: 4 - 344
Aligned: 341
Modelled: 341
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: A: PDB Molecule:probable dehydrogenase;
PDBTitle: the crystal structure of the putative dehydrogenase from bordetella2 bronchiseptica rb50

Phyre2

PDB 3q2k chain B

3D model

Region: 3 - 345
Aligned: 318
Modelled: 318
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of the wlba dehydrogenase from bordetella pertussis2 in complex with nadh and udp-glcnaca

Phyre2

PDB 3euw chain B

3D model

Region: 1 - 346
Aligned: 323
Modelled: 324
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: B: PDB Molecule:myo-inositol dehydrogenase;
PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032

Phyre2

PDB 3evn chain A

3D model

Region: 4 - 341
Aligned: 313
Modelled: 317
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of putative oxidoreductase from streptococcus2 agalactiae 2603v/r

Phyre2

PDB 3ezy chain B

3D model

Region: 5 - 346
Aligned: 320
Modelled: 321
Confidence: 100.0%
Identity: 21%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure of probable dehydrogenase tm_0414 from2 thermotoga maritima

Phyre2

PDB 3dty chain A

3D model

Region: 1 - 345
Aligned: 334
Modelled: 345
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of an oxidoreductase from pseudomonas2 syringae

Phyre2

PDB 1zh8 chain B

3D model

Region: 3 - 344
Aligned: 312
Modelled: 311
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of oxidoreductase (tm0312) from thermotoga maritima2 at 2.50 a resolution

Phyre2

PDB 1evj chain C

3D model

Region: 3 - 345
Aligned: 313
Modelled: 313
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: C: PDB Molecule:glucose-fructose oxidoreductase;
PDBTitle: crystal structure of glucose-fructose oxidoreductase (gfor)2 delta1-22 s64d

Phyre2
1

c3kuxA_
2

c3gfgB_
3

c3e18A_
4

c3fhlC_
5

c3e82A_
6

c3f4lF_
7

c1h6dL_
8

c1ofgF_
9

c3oqbF_
10

c3fd8A_
11

c3db2C_
12

c2glxD_
13

c3moiA_
14

c3q2kB_
15

c3euwB_
16

c3evnA_
17

c3ezyB_
18

c3dtyA_
19

c1zh8B_
20

c1evjC_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3kuxA_



100.0 70 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: structure of the ypo2259 putative oxidoreductase from yersinia pestis
2c3gfgB_



100.0 38 PDB header:oxidoreductase
Chain: B: PDB Molecule:uncharacterized oxidoreductase yvaa;
PDBTitle: structure of putative oxidoreductase yvaa from bacillus subtilis in2 triclinic form
3c3e18A_



100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of nad-binding protein from listeria innocua
4c3fhlC_



100.0 40 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from bacteroides2 fragilis nctc 9343
5c3e82A_



100.0 49 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from2 klebsiella pneumoniae
6c3f4lF_



100.0 37 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative oxidoreductase yhhx;
PDBTitle: crystal structure of a probable oxidoreductase yhhx in2 triclinic form. northeast structural genomics target er647
7c1h6dL_



100.0 17 PDB header:protein translocation
Chain: L: PDB Molecule:precursor form of glucose-fructose
PDBTitle: oxidized precursor form of glucose-fructose oxidoreductase2 from zymomonas mobilis complexed with glycerol
8c1ofgF_



100.0 17 PDB header:oxidoreductase
Chain: F: PDB Molecule:glucose-fructose oxidoreductase;
PDBTitle: glucose-fructose oxidoreductase
9c3oqbF_



100.0 18 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase from bradyrhizobium2 japonicum usda 110
10c3fd8A_



100.0 33 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis
11c3db2C_



100.0 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase;
PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution
12c2glxD_



100.0 21 PDB header:oxidoreductase
Chain: D: PDB Molecule:1,5-anhydro-d-fructose reductase;
PDBTitle: crystal structure analysis of bacterial 1,5-af reductase
13c3moiA_



100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable dehydrogenase;
PDBTitle: the crystal structure of the putative dehydrogenase from bordetella2 bronchiseptica rb50
14c3q2kB_



100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of the wlba dehydrogenase from bordetella pertussis2 in complex with nadh and udp-glcnaca
15c3euwB_



100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:myo-inositol dehydrogenase;
PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032
16c3evnA_



100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of putative oxidoreductase from streptococcus2 agalactiae 2603v/r
17c3ezyB_



100.0 21 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure of probable dehydrogenase tm_0414 from2 thermotoga maritima
18c3dtyA_



100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of an oxidoreductase from pseudomonas2 syringae
19c1zh8B_



100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of oxidoreductase (tm0312) from thermotoga maritima2 at 2.50 a resolution
20c1evjC_



100.0 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:glucose-fructose oxidoreductase;
PDBTitle: crystal structure of glucose-fructose oxidoreductase (gfor)2 delta1-22 s64d
21c2q4eB_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable oxidoreductase at4g09670;
PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at4g09670
22c3e9mC_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: C: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis
23c2o48X_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: X: PDB Molecule:dimeric dihydrodiol dehydrogenase;
PDBTitle: crystal structure of mammalian dimeric dihydrodiol dehydrogenase
24c3rbvA_



not modelled 100.0 21 PDB header:sugar binding protein
Chain: A: PDB Molecule:sugar 3-ketoreductase;
PDBTitle: crystal structure of kijd10, a 3-ketoreductase from actinomadura2 kijaniata incomplex with nadp
25c3btuD_



not modelled 100.0 20 PDB header:transcription
Chain: D: PDB Molecule:galactose/lactose metabolism regulatory protein
PDBTitle: crystal structure of the super-repressor mutant of gal80p2 from saccharomyces cerevisiae; gal80(s2) [e351k]
26c3ceaA_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:myo-inositol 2-dehydrogenase;
PDBTitle: crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from2 lactobacillus plantarum at 2.40 a resolution
27c3v5nA_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase;
PDBTitle: the crystal structure of oxidoreductase from sinorhizobium meliloti
28c3nt5B_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase;
PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose
29c3m2tA_



not modelled 100.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable dehydrogenase;
PDBTitle: the crystal structure of dehydrogenase from chromobacterium2 violaceum
30c2nvwB_



not modelled 100.0 18 PDB header:transcription
Chain: B: PDB Molecule:galactose/lactose metabolism regulatory protein
PDBTitle: crystal sctucture of transcriptional regulator gal80p from2 kluyveromymes lactis
31c2p2sA_



not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase (yp_050235.1) from2 erwinia carotovora atroseptica scri1043 at 1.25 a resolution
32c3ec7C_



not modelled 100.0 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dehydrogenase;
PDBTitle: crystal structure of putative dehydrogenase from salmonella2 typhimurium lt2
33c3ip3D_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase, putative;
PDBTitle: structure of putative oxidoreductase (tm_0425) from2 thermotoga maritima
34c2ixaA_



not modelled 100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase;
PDBTitle: a-zyme, n-acetylgalactosaminidase
35c3c1aB_



not modelled 100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase (zp_00056571.1) from2 magnetospirillum magnetotacticum ms-1 at 1.85 a resolution
36c3uuwB_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase with nad(p)-binding rossmann-fold
PDBTitle: 1.63 angstrom resolution crystal structure of dehydrogenase (mvim)2 from clostridium difficile.
37c1xeaD_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of a gfo/idh/moca family oxidoreductase2 from vibrio cholerae
38c2ho3D_



not modelled 100.0 23 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of oxidoreductase, gfo/idh/moca family from2 streptococcus pneumoniae
39c1tltB_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase (virulence factor mvim homolog);
PDBTitle: crystal structure of a putative oxidoreductase (virulence factor mvim2 homolog)
40c1lc3A_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:biliverdin reductase a;
PDBTitle: crystal structure of a biliverdin reductase enzyme-cofactor2 complex
41c3oa2B_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:wbpb;
PDBTitle: crystal structure of the wlba (wbpb) dehydrogenase from pseudomonas2 aeruginosa in complex with nad at 1.5 angstrom resolution
42c3oa0B_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:lipopolysaccaride biosynthesis protein wbpb;
PDBTitle: crystal structure of the wlba (wbpb) dehydrogenase from thermus2 thermophilus in complex with nad and udp-glcnaca
43d1h6da1



not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
44d1ryda1



not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
45d1zh8a1



not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
46d2nvwa1



not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
47d1ydwa1



not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
48d1xeaa1



not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
49d1lc0a1



not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
50d1tlta1



not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
51c1j5pA_



not modelled 99.9 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:aspartate dehydrogenase;
PDBTitle: crystal structure of aspartate dehydrogenase (tm1643) from thermotoga2 maritima at 1.9 a resolution
52d1f06a1



not modelled 99.9 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
53c3dapB_



not modelled 99.9 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:diaminopimelic acid dehydrogenase;
PDBTitle: c. glutamicum dap dehydrogenase in complex with nadp+ and2 the inhibitor 5s-isoxazoline
54c2dc1A_



not modelled 99.8 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-aspartate dehydrogenase;
PDBTitle: crystal structure of l-aspartate dehydrogenase from2 hyperthermophilic archaeon archaeoglobus fulgidus
55d2nu7a1



not modelled 99.8 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:CoA-binding domain
56d1oi7a1



not modelled 99.8 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:CoA-binding domain
57c1ebuA_



not modelled 99.8 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: homoserine dehydrogenase complex with nad analogue and l-2 homoserine
58c3mtjA_



not modelled 99.8 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a
59d1ebfa1



not modelled 99.7 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
60d1j5pa4



not modelled 99.7 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
61d1euca1



not modelled 99.7 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:CoA-binding domain
62d1zh8a2



not modelled 99.7 16 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:Glucose 6-phosphate dehydrogenase-like
63c3do5A_



not modelled 99.7 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of putative homoserine dehydrogenase (np_069768.1)2 from archaeoglobus fulgidus at 2.20 a resolution
64c3bioB_



not modelled 99.7 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of oxidoreductase (gfo/idh/moca family member) from2 porphyromonas gingivalis w83
65d2dt5a2



not modelled 99.6 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Transcriptional repressor Rex, C-terminal domain
66d2nvwa2



not modelled 99.6 13 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:Glucose 6-phosphate dehydrogenase-like
67d1h6da2



not modelled 99.6 13 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:Glucose 6-phosphate dehydrogenase-like
68c1drwA_



not modelled 99.5 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrodipicolinate reductase;
PDBTitle: escherichia coli dhpr/nhdh complex
69c3ketA_



not modelled 99.5 21 PDB header:transcription/dna
Chain: A: PDB Molecule:redox-sensing transcriptional repressor rex;
PDBTitle: crystal structure of a rex-family transcriptional regulatory protein2 from streptococcus agalactiae bound to a palindromic operator
70d1ydwa2



not modelled 99.5 17 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:Glucose 6-phosphate dehydrogenase-like
71c3ic5A_



not modelled 99.5 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative saccharopine dehydrogenase;
PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi.
72d1e5qa1



not modelled 99.4 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
73c2dt5A_



not modelled 99.4 16 PDB header:dna binding protein
Chain: A: PDB Molecule:at-rich dna-binding protein;
PDBTitle: crystal structure of ttha1657 (at-rich dna-binding protein) from2 thermus thermophilus hb8
74c2axqA_



not modelled 99.4 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae
75c2ejwB_



not modelled 99.4 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:homoserine dehydrogenase;
PDBTitle: homoserine dehydrogenase from thermus thermophilus hb8
76c2yv1A_



not modelled 99.2 17 PDB header:ligase
Chain: A: PDB Molecule:succinyl-coa ligase [adp-forming] subunit alpha;
PDBTitle: crystal structure of succinyl-coa synthetase alpha chain from2 methanocaldococcus jannaschii dsm 2661
77c1e5lA_



not modelled 99.2 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine reductase;
PDBTitle: apo saccharopine reductase from magnaporthe grisea
78c3hdjA_



not modelled 99.1 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:probable ornithine cyclodeaminase;
PDBTitle: the crystal structure of probable ornithine cyclodeaminase from2 bordetella pertussis tohama i
79d1omoa_



not modelled 99.1 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Ornithine cyclodeaminase-like
80c2z2vA_



not modelled 99.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein ph1688;
PDBTitle: crystal structure of l-lysine dehydrogenase from2 hyperthermophilic archaeon pyrococcus horikoshii
81d1xeaa2



not modelled 99.0 9 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:Glucose 6-phosphate dehydrogenase-like
82c3c8mA_



not modelled 98.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of homoserine dehydrogenase from thermoplasma2 volcanium
83c1r0lD_



not modelled 98.9 13 PDB header:oxidoreductase
Chain: D: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase;
PDBTitle: 1-deoxy-d-xylulose 5-phosphate reductoisomerase from2 zymomonas mobilis in complex with nadph
84c2nu8D_



not modelled 98.8 13 PDB header:ligase
Chain: D: PDB Molecule:succinyl-coa ligase [adp-forming] subunit alpha;
PDBTitle: c123at mutant of e. coli succinyl-coa synthetase
85c3ijpA_



not modelled 98.8 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrodipicolinate reductase;
PDBTitle: crystal structure of dihydrodipicolinate reductase from2 bartonella henselae at 2.0a resolution
86c2i99A_



not modelled 98.8 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:mu-crystallin homolog;
PDBTitle: crystal structure of human mu_crystallin at 2.6 angstrom
87d1diha1



not modelled 98.7 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
88c2ozpA_



not modelled 98.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:n-acetyl-gamma-glutamyl-phosphate reductase;
PDBTitle: crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase2 (ttha1904) from thermus thermophilus
89c3a14B_



not modelled 98.7 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase;
PDBTitle: crystal structure of dxr from thermotoga maritima, in complex with2 nadph
90c1b7gO_



not modelled 98.7 13 PDB header:oxidoreductase
Chain: O: PDB Molecule:protein (glyceraldehyde 3-phosphate dehydrogenase);
PDBTitle: glyceraldehyde 3-phosphate dehydrogenase
91c1oi7A_



not modelled 98.7 19 PDB header:synthetase
Chain: A: PDB Molecule:succinyl-coa synthetase alpha chain;
PDBTitle: the crystal structure of succinyl-coa synthetase alpha2 subunit from thermus thermophilus
92c2czcD_



not modelled 98.7 21 PDB header:oxidoreductase
Chain: D: PDB Molecule:glyceraldehyde-3-phosphate dehydrogenase;
PDBTitle: crystal structure of glyceraldehyde-3-phosphate dehydrogenase from2 pyrococcus horikoshii ot3
93c3l6dB_



not modelled 98.7 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440
94c1yl7F_



not modelled 98.6 18 PDB header:oxidoreductase
Chain: F: PDB Molecule:dihydrodipicolinate reductase;
PDBTitle: the crystal structure of mycobacterium tuberculosis2 dihydrodipicolinate reductase (rv2773c) in complex with nadh (crystal3 form c)
95c2yv2A_



not modelled 98.6 17 PDB header:ligase
Chain: A: PDB Molecule:succinyl-coa synthetase alpha chain;
PDBTitle: crystal structure of succinyl-coa synthetase alpha chain from2 aeropyrum pernix k1
96c3cumA_



not modelled 98.6 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1
97d1cf2o1



not modelled 98.6 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
98c3ckyA_



not modelled 98.6 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase;
PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation
99c3ingA_



not modelled 98.5 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of homoserine dehydrogenase (np_394635.1) from2 thermoplasma acidophilum at 1.95 a resolution
100c2p4qA_



not modelled 98.5 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating 1;
PDBTitle: crystal structure analysis of gnd1 in saccharomyces cerevisiae
101d1yl7a1



not modelled 98.5 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
102c2jcyA_



not modelled 98.5 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase;
PDBTitle: x-ray structure of mutant 1-deoxy-d-xylulose 5-phosphate2 reductoisomerase, dxr, rv2870c, from mycobacterium3 tuberculosis
103c3fwnB_



not modelled 98.5 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: dimeric 6-phosphogluconate dehydrogenase complexed with 6-2 phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate
104d1nvmb1



not modelled 98.5 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
105c1nvmB_



not modelled 98.5 17 PDB header:lyase/oxidoreductase
Chain: B: PDB Molecule:acetaldehyde dehydrogenase (acylating);
PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate
106c3d1lB_



not modelled 98.5 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis
107c3nklA_



not modelled 98.5 14 PDB header:oxidoreductase/lyase
Chain: A: PDB Molecule:udp-d-quinovosamine 4-dehydrogenase;
PDBTitle: crystal structure of udp-d-quinovosamine 4-dehydrogenase from vibrio2 fischeri
108c2eghA_



not modelled 98.4 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase;
PDBTitle: crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase2 complexed with a magnesium ion, nadph and fosmidomycin
109c3qhaB_



not modelled 98.4 10 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from mycobacterium2 avium 104
110c3g0oA_



not modelled 98.4 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium
111c2uyyD_



not modelled 98.4 10 PDB header:cytokine
Chain: D: PDB Molecule:n-pac protein;
PDBTitle: structure of the cytokine-like nuclear factor n-pac
112c1pgjA_



not modelled 98.4 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: x-ray structure of 6-phosphogluconate dehydrogenase from the protozoan2 parasite t. brucei
113c2iz1C_



not modelled 98.4 12 PDB header:oxidoreductase
Chain: C: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: 6pdh complexed with pex inhibitor synchrotron data
114d1tlta2



not modelled 98.4 13 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:Glucose 6-phosphate dehydrogenase-like
115d1r0ka2



not modelled 98.4 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
116c3b1fA_



not modelled 98.4 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 mutans
117d1i36a2



not modelled 98.4 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
118c2ph5A_



not modelled 98.4 13 PDB header:transferase
Chain: A: PDB Molecule:homospermidine synthase;
PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54
119c1pgqA_



not modelled 98.3 11 PDB header:oxidoreductase (choh(d)-nadp+(a))
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: crystallographic study of coenzyme, coenzyme analogue and substrate2 binding in 6-phosphogluconate dehydrogenase: implications for nadp3 specificity and the enzyme mechanism
120c1vpdA_



not modelled 98.3 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronate semialdehyde reductase;
PDBTitle: x-ray crystal structure of tartronate semialdehyde reductase2 [salmonella typhimurium lt2]

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0