Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	C	S	I	F	G	V	F	D	I	K	T	D	A	V	E	L	R	K	K	A	L	E	L	S	R	L	M	R	H	R	G	P	D	W	S	G	I	Y	A	S	D	N	A	I	L	A	H	E	R	L	S	I	V	D	V	N	A	G	A
Secondary structure
SS confidence
Disorder		?	?										?	?		?	?	?													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	P	L	Y	N	Q	Q	K	T	H	V	L	A	V	N	G	E	I	Y	N	H	Q	A	L	R	A	E	Y	G	D	R	Y	Q	F	Q	T	G	S	D	C	E	V	I	L	A	L	Y	Q	E	K	G	P	E	F	L	D	D	L	Q	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		M	F	A	F	A	L	Y	D	S	E	K	D	A	Y	L	I	G	R	D	H	L	G	I	I	P	L	Y	M	G	Y	D	E	H	G	Q	L	Y	V	A	S	E	M	K	A	L	V	P	V	C	R	T	I	K	E	F	P	A	G	S	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	W	S	Q	D	G	E	I	R	S	Y	Y	H	R	D	W	F	D	Y	D	A	V	K	D	N	V	T	D	K	N	E	L	R	Q	A	L	E	D	S	V	K	S	H	L	M	S	D	V	P	Y	G	V	L	L	S	G	G	L	D	S
Secondary structure
SS confidence
Disorder																				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	I	I	S	A	I	T	K	K	Y	A	A	R	R	V	E	D	Q	E	R	S	E	A	W	W	P	Q	L	H	S	F	A	V	G	L	P	G	S	P	D	L	K	A	A	Q	E	V	A	N	H	L	G	T	V	H	H	E	I	H	F
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		T	V	Q	E	G	L	D	A	I	R	D	V	I	Y	H	I	E	T	Y	D	V	T	T	I	R	A	S	T	P	M	Y	L	M	S	R	K	I	K	A	M	G	I	K	M	V	L	S	G	E	G	S	D	E	V	F	G	G	Y	L	Y
Secondary structure
SS confidence
Disorder																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		F	H	K	A	P	N	A	K	E	L	H	E	E	T	V	R	K	L	L	A	L	H	M	Y	D	C	A	R	A	N	K	A	M	S	A	W	G	V	E	A	R	V	P	F	L	D	K	K	F	L	D	V	A	M	R	I	N	P	Q	D
Secondary structure
SS confidence
Disorder								?																								?	?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		K	M	C	G	N	G	K	M	E	K	H	I	L	R	E	C	F	E	A	Y	L	P	A	S	V	A	W	R	Q	K	E	Q	F	S	D	G	V	G	Y	S	W	I	D	T	L	K	E	V	A	A	Q	Q	V	S	D	Q	Q	L	E	T
Secondary structure
SS confidence
Disorder				?																																	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		A	R	F	R	F	P	Y	N	T	P	T	S	K	E	A	Y	L	Y	R	E	I	F	E	E	L	F	P	L	P	S	A	A	E	C	V	P	G	G	P	S	V	A	C	S	S	A	K	A	I	E	W	D	E	A	F	K	K	M	D	D
Secondary structure
SS confidence
Disorder		?																																																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.
Sequence		P	S	G	R	A	V	G	V	H	Q	S	A	Y	K
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1ct9 chain D Region: 2 - 517 Aligned: 495 Modelled: 516 Confidence: 100.0% Identity: 100% PDB header:ligase Chain: D: PDB Molecule:asparagine synthetase b; PDBTitle: crystal structure of asparagine synthetase b from2 escherichia coli Phyre2 PDB 1q15 chain A Region: 29 - 474 Aligned: 413 Modelled: 428 Confidence: 100.0% Identity: 22% PDB header:biosynthetic protein Chain: A: PDB Molecule:cara; PDBTitle: carbapenam synthetase Phyre2 PDB 1m1z chain B Region: 24 - 454 Aligned: 399 Modelled: 417 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: B: PDB Molecule:beta-lactam synthetase; PDBTitle: beta-lactam synthetase apo enzyme Phyre2 PDB 1ct9 chain A domain 1 Region: 194 - 517 Aligned: 305 Modelled: 308 Confidence: 100.0% Identity: 99% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 PDB 1jgt chain A domain 1 Region: 201 - 504 Aligned: 283 Modelled: 286 Confidence: 100.0% Identity: 21% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 PDB 1q15 chain A domain 1 Region: 195 - 475 Aligned: 260 Modelled: 267 Confidence: 100.0% Identity: 23% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 PDB 1ct9 chain A domain 2 Region: 2 - 193 Aligned: 192 Modelled: 192 Confidence: 100.0% Identity: 99% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1q15 chain A domain 2 Region: 24 - 187 Aligned: 154 Modelled: 164 Confidence: 100.0% Identity: 18% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1gph chain 1 Region: 2 - 247 Aligned: 236 Modelled: 244 Confidence: 100.0% Identity: 27% PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis Phyre2 PDB 1ecj chain B Region: 2 - 247 Aligned: 236 Modelled: 246 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer Phyre2 PDB 1jxa chain A Region: 2 - 191 Aligned: 180 Modelled: 185 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: A: PDB Molecule:glucosamine 6-phosphate synthase; PDBTitle: glucosamine 6-phosphate synthase with glucose 6-phosphate Phyre2 PDB 1jgt chain A domain 2 Region: 1 - 197 Aligned: 181 Modelled: 197 Confidence: 100.0% Identity: 24% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1gph chain 1 domain 2 Region: 2 - 199 Aligned: 191 Modelled: 192 Confidence: 100.0% Identity: 27% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1ecf chain A domain 2 Region: 2 - 198 Aligned: 192 Modelled: 197 Confidence: 100.0% Identity: 27% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1xff chain A Region: 2 - 191 Aligned: 182 Modelled: 190 Confidence: 100.0% Identity: 29% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1xng chain A domain 1 Region: 203 - 459 Aligned: 237 Modelled: 244 Confidence: 99.9% Identity: 19% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 PDB 1ofd chain A domain 3 Region: 2 - 193 Aligned: 184 Modelled: 192 Confidence: 99.8% Identity: 23% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1te5 chain A Region: 2 - 190 Aligned: 176 Modelled: 183 Confidence: 99.8% Identity: 22% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 1ea0 chain A domain 3 Region: 2 - 193 Aligned: 184 Modelled: 190 Confidence: 99.8% Identity: 26% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Class II glutamine amidotransferases Phyre2 PDB 3mdn chain D Region: 2 - 191 Aligned: 159 Modelled: 173 Confidence: 99.6% Identity: 21% PDB header:transferase Chain: D: PDB Molecule:glutamine aminotransferase class-ii domain protein; PDBTitle: structure of glutamine aminotransferase class-ii domain protein2 (spo2029) from silicibacter pomeroyi Phyre2 1 c1ct9D_ 2 c1q15A_ 3 c1m1zB_ 4 d1ct9a1 5 d1jgta1 6 d1q15a1 7 d1ct9a2 8 d1q15a2 9 c1gph1_ 10 c1ecjB_ 11 c1jxaA_ 12 d1jgta2 13 d1gph12 14 d1ecfa2 15 d1xffa_ 16 d1xnga1 17 d1ofda3 18 d1te5a_ 19 d1ea0a3 20 c3mdnD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1ct9D_ 100.0 100 PDB header:ligase Chain: D: PDB Molecule:asparagine synthetase b; PDBTitle: crystal structure of asparagine synthetase b from2 escherichia coli 2 c1q15A_ 100.0 22 PDB header:biosynthetic protein Chain: A: PDB Molecule:cara; PDBTitle: carbapenam synthetase 3 c1m1zB_ 100.0 25 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactam synthetase; PDBTitle: beta-lactam synthetase apo enzyme 4 d1ct9a1 100.0 99 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 5 d1jgta1 100.0 21 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 6 d1q15a1 100.0 23 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 7 d1ct9a2 100.0 99 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Class II glutamine amidotransferases 8 d1q15a2 100.0 18 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Class II glutamine amidotransferases 9 c1gph1_ 100.0 27 PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis 10 c1ecjB_ 100.0 25 PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer 11 c1jxaA_ 100.0 31 PDB header:transferase Chain: A: PDB Molecule:glucosamine 6-phosphate synthase; PDBTitle: glucosamine 6-phosphate synthase with glucose 6-phosphate 12 d1jgta2 100.0 24 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Class II glutamine amidotransferases 13 d1gph12 100.0 27 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Class II glutamine amidotransferases 14 d1ecfa2 100.0 27 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Class II glutamine amidotransferases 15 d1xffa_ 100.0 29 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Class II glutamine amidotransferases 16 d1xnga1 99.9 19 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 17 d1ofda3 99.8 23 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Class II glutamine amidotransferases 18 d1te5a_ 99.8 22 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Class II glutamine amidotransferases 19 d1ea0a3 99.8 26 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Class II glutamine amidotransferases 20 c3mdnD_ 99.6 21 PDB header:transferase Chain: D: PDB Molecule:glutamine aminotransferase class-ii domain protein; PDBTitle: structure of glutamine aminotransferase class-ii domain protein2 (spo2029) from silicibacter pomeroyi 21 c2e18B_ not modelled 99.5 18 PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of project ph0182 from pyrococcus horikoshii ot3 22 c3fiuD_ not modelled 99.5 18 PDB header:ligase Chain: D: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nmn synthetase from francisella tularensis 23 c3p52B_ not modelled 99.4 19 PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: nh3-dependent nad synthetase from campylobacter jejuni subsp. jejuni2 nctc 11168 in complex with the nitrate ion 24 d2pg3a1 not modelled 99.3 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 25 c3bl5E_ not modelled 99.2 18 PDB header:hydrolase Chain: E: PDB Molecule:queuosine biosynthesis protein quec; PDBTitle: crystal structure of quec from bacillus subtilis: an enzyme2 involved in preq1 biosynthesis 26 c3k32D_ not modelled 99.1 25 PDB header:transferase Chain: D: PDB Molecule:uncharacterized protein mj0690; PDBTitle: the crystal structure of predicted subunit of trna2 methyltransferase from methanocaldococcus jannaschii dsm 27 d1gpma1 not modelled 99.0 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 28 d1k92a1 not modelled 99.0 19 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 29 c1lm1A_ not modelled 98.9 25 PDB header:oxidoreductase Chain: A: PDB Molecule:ferredoxin-dependent glutamate synthase; PDBTitle: structural studies on the synchronization of catalytic centers in2 glutamate synthase: native enzyme 30 d1wy5a1 not modelled 98.9 10 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PP-loop ATPase 31 d1j20a1 not modelled 98.9 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 32 c3dpiA_ not modelled 98.8 16 PDB header:ligase Chain: A: PDB Molecule:nad+ synthetase; PDBTitle: crystal structure of nad+ synthetase from burkholderia pseudomallei 33 c3q4gA_ not modelled 98.8 12 PDB header:ligase Chain: A: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nad synthetase from vibrio cholerae 34 c2ywcC_ not modelled 98.8 16 PDB header:ligase Chain: C: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: crystal structure of gmp synthetase from thermus thermophilus in2 complex with xmp 35 c1gpmD_ not modelled 98.8 16 PDB header:transferase (glutamine amidotransferase) Chain: D: PDB Molecule:gmp synthetase; PDBTitle: escherichia coli gmp synthetase complexed with amp and pyrophosphate 36 d1kqpa_ not modelled 98.7 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 37 c1k97A_ not modelled 98.7 19 PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline 38 c2hmaA_ not modelled 98.7 17 PDB header:transferase Chain: A: PDB Molecule:probable trna (5-methylaminomethyl-2-thiouridylate)- PDBTitle: the crystal structure of trna (5-methylaminomethyl-2-thiouridylate)-2 methyltransferase trmu from streptococcus pneumoniae 39 d1vl2a1 not modelled 98.7 19 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 40 d2c5sa1 not modelled 98.6 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ThiI-like 41 c2derA_ not modelled 98.6 19 PDB header:transferase/rna Chain: A: PDB Molecule:trna-specific 2-thiouridylase mnma; PDBTitle: cocrystal structure of an rna sulfuration enzyme mnma and2 trna-glu in the initial trna binding state 42 c3tqiB_ not modelled 98.6 16 PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: structure of the gmp synthase (guaa) from coxiella burnetii 43 c2vdcF_ not modelled 98.5 23 PDB header:oxidoreductase Chain: F: PDB Molecule:glutamate synthase [nadph] large chain; PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications. 44 c2e21A_ not modelled 98.5 11 PDB header:ligase Chain: A: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus. 45 c3n05B_ not modelled 98.5 17 PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of nh3-dependent nad+ synthetase from streptomyces2 avermitilis 46 c2nz2A_ not modelled 98.5 20 PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of human argininosuccinate synthase in complex with2 aspartate and citrulline 47 c2vxoB_ not modelled 98.5 18 PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: human gmp synthetase in complex with xmp 48 d1ni5a1 not modelled 98.4 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PP-loop ATPase 49 c1kh2D_ not modelled 98.4 21 PDB header:ligase Chain: D: PDB Molecule:argininosuccinate synthetase; PDBTitle: crystal structure of thermus thermophilus hb82 argininosuccinate synthetase in complex with atp 50 d1wxia1 not modelled 98.4 9 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 51 c2dplA_ not modelled 98.3 16 PDB header:ligase Chain: A: PDB Molecule:gmp synthase [glutamine-hydrolyzing] subunit b; PDBTitle: crystal structure of the gmp synthase from pyrococcus horikoshii ot3 52 c2c5sA_ not modelled 98.3 18 PDB header:rna-binding protein Chain: A: PDB Molecule:probable thiamine biosynthesis protein thii; PDBTitle: crystal structure of bacillus anthracis thii, a trna-2 modifying enzyme containing the predicted rna-binding3 thump domain 53 c3dlaD_ not modelled 98.3 20 PDB header:ligase Chain: D: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: x-ray crystal structure of glutamine-dependent nad+ synthetase from2 mycobacterium tuberculosis bound to naad+ and don 54 c3uowB_ not modelled 98.3 15 PDB header:ligase Chain: B: PDB Molecule:gmp synthetase; PDBTitle: crystal structure of pf10_0123, a gmp synthetase from plasmodium2 falciparum 55 c3a2kB_ not modelled 98.3 13 PDB header:ligase/rna Chain: B: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils complexed with trna 56 c1vl2C_ not modelled 98.2 18 PDB header:ligase Chain: C: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of argininosuccinate synthase (tm1780) from2 thermotoga maritima at 1.65 a resolution 57 c1ni5A_ not modelled 98.0 12 PDB header:cell cycle Chain: A: PDB Molecule:putative cell cycle protein mesj; PDBTitle: structure of the mesj pp-atpase from escherichia coli 58 d1sura_ not modelled 97.9 11 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PAPS reductase-like 59 c3ilvA_ not modelled 97.5 17 PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: crystal structure of a glutamine-dependent nad(+) synthetase2 from cytophaga hutchinsonii 60 c2o8vA_ not modelled 97.5 11 PDB header:oxidoreductase Chain: A: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: paps reductase in a covalent complex with thioredoxin c35a 61 d1zuna1 not modelled 97.5 8 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PAPS reductase-like 62 d1ru8a_ not modelled 97.3 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 63 c1zunA_ not modelled 97.2 8 PDB header:transferase Chain: A: PDB Molecule:sulfate adenylyltransferase subunit 2; PDBTitle: crystal structure of a gtp-regulated atp sulfurylase2 heterodimer from pseudomonas syringae 64 c2oq2B_ not modelled 97.1 13 PDB header:oxidoreductase Chain: B: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: crystal structure of yeast paps reductase with pap, a product complex 65 c2goyC_ not modelled 97.1 15 PDB header:oxidoreductase Chain: C: PDB Molecule:adenosine phosphosulfate reductase; PDBTitle: crystal structure of assimilatory adenosine 5'-2 phosphosulfate reductase with bound aps 66 d1vbka1 not modelled 96.2 19 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ThiI-like 67 d2d13a1 not modelled 95.9 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 68 c3g59A_ not modelled 95.1 8 PDB header:transferase Chain: A: PDB Molecule:fmn adenylyltransferase; PDBTitle: crystal structure of candida glabrata fmn2 adenylyltransferase in complex with atp 69 c2wsiA_ not modelled 94.8 10 PDB header:transferase Chain: A: PDB Molecule:fad synthetase; PDBTitle: crystal structure of yeast fad synthetase (fad1) in complex2 with fad 70 c1vbkA_ not modelled 90.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ph1313; PDBTitle: crystal structure of ph1313 from pyrococcus horikoshii ot3 71 c2cb1A_ not modelled 70.5 14 PDB header:lyase Chain: A: PDB Molecule:o-acetyl homoserine sulfhydrylase; PDBTitle: crystal structure of o-actetyl homoserine sulfhydrylase2 from thermus thermophilus hb8,oah2. 72 c3o1lB_ not modelled 65.6 10 PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pspto_4314)2 from pseudomonas syringae pv. tomato str. dc3000 at 2.20 a resolution 73 c2j0eA_ not modelled 37.6 13 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: three dimensional structure and catalytic mechanism of 6-2 phosphogluconolactonase from trypanosoma brucei 74 d1dv5a_ not modelled 37.1 19 Fold:Acyl carrier protein-like Superfamily:ACP-like Family:apo-D-alanyl carrier protein 75 c3sbtB_ not modelled 37.0 13 PDB header:splicing Chain: B: PDB Molecule:a1 cistron-splicing factor aar2; PDBTitle: crystal structure of a aar2-prp8 complex 76 c3nwpA_ not modelled 36.2 11 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of a 6-phosphogluconolactonase (sbal_2240) from2 shewanella baltica os155 at 1.40 a resolution 77 c3kx6C_ not modelled 35.4 17 PDB header:lyase Chain: C: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: crystal structure of fructose-1,6-bisphosphate aldolase from babesia2 bovis at 2.1a resolution 78 c3n0vD_ not modelled 35.4 12 PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pp_0327)2 from pseudomonas putida kt2440 at 2.25 a resolution 79 c3mbfA_ not modelled 32.8 16 PDB header:lyase Chain: A: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: crystal structure of fructose bisphosphate aldolase from2 encephalitozoon cuniculi, bound to fructose 1,6-bisphosphate 80 d1md6a_ not modelled 29.4 26 Fold:beta-Trefoil Superfamily:Cytokine Family:Interleukin-1 (IL-1) 81 c2b8tA_ not modelled 27.8 13 PDB header:transferase Chain: A: PDB Molecule:thymidine kinase; PDBTitle: crystal structure of thymidine kinase from u.urealyticum in2 complex with thymidine 82 d2b8ta1 not modelled 27.2 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Type II thymidine kinase 83 c3icoA_ not modelled 25.7 14 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of 6-phosphogluconolactonase from2 mycobacterium tuberculosis 84 d1qo5b_ not modelled 25.5 22 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 85 d1hkoa_ not modelled 24.7 24 Fold:Cytochrome b5-like heme/steroid binding domain Superfamily:Cytochrome b5-like heme/steroid binding domain Family:Cytochrome b5 86 c3mmtC_ not modelled 24.6 25 PDB header:hydrolase Chain: C: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: crystal structure of fructose bisphosphate aldolase from bartonella2 henselae, bound to fructose bisphosphate 87 c3lhiA_ not modelled 24.5 19 PDB header:hydrolase Chain: A: PDB Molecule:putative 6-phosphogluconolactonase; PDBTitle: crystal structure of putative 6-2 phosphogluconolactonase(yp_207848.1) from neisseria3 gonorrhoeae fa 1090 at 1.33 a resolution 88 d1b4ub_ not modelled 24.3 26 Fold:Phosphorylase/hydrolase-like Superfamily:LigB-like Family:LigB-like 89 d1mj4a_ not modelled 23.5 6 Fold:Cytochrome b5-like heme/steroid binding domain Superfamily:Cytochrome b5-like heme/steroid binding domain Family:Cytochrome b5 90 c3rfuC_ not modelled 23.3 21 PDB header:hydrolase, membrane protein Chain: C: PDB Molecule:copper efflux atpase; PDBTitle: crystal structure of a copper-transporting pib-type atpase 91 d1zaia1 not modelled 22.9 23 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 92 d1iccc_ not modelled 22.6 18 Fold:Cytochrome b5-like heme/steroid binding domain Superfamily:Cytochrome b5-like heme/steroid binding domain Family:Cytochrome b5 93 c3hn6D_ not modelled 21.7 14 PDB header:isomerase Chain: D: PDB Molecule:glucosamine-6-phosphate deaminase; PDBTitle: crystal structure of glucosamine-6-phosphate deaminase from borrelia2 burgdorferi 94 d1fdja_ not modelled 21.7 22 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 95 d1f2ja_ not modelled 21.7 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 96 c1x3xA_ not modelled 21.5 24 PDB header:electron transport Chain: A: PDB Molecule:cytochrome b5; PDBTitle: crystal structure of cytochrome b5 from ascaris suum 97 d2qapa1 not modelled 21.4 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 98 c2qapC_ not modelled 21.4 19 PDB header:lyase Chain: C: PDB Molecule:fructose-1,6-bisphosphate aldolase; PDBTitle: fructose-1,6-bisphosphate aldolase from leishmania mexicana 99 c3ndnC_ not modelled 21.2 11 PDB header:lyase Chain: C: PDB Molecule:o-succinylhomoserine sulfhydrylase; PDBTitle: crystal structure of o-succinylhomoserine sulfhydrylase from2 mycobacterium tuberculosis covalently bound to pyridoxal-5-phosphate 100 d1kbia2 not modelled 21.0 24 Fold:Cytochrome b5-like heme/steroid binding domain Superfamily:Cytochrome b5-like heme/steroid binding domain Family:Cytochrome b5 101 c9paiB_ not modelled 20.9 14 PDB header:hydrolase inhibitor Chain: B: PDB Molecule:protein (plasminogen activator inhibitor-1) residues 365- PDBTitle: cleaved substrate variant of plasminogen activator inhibitor-1 102 c2pc4B_ not modelled 20.8 20 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: crystal structure of fructose-bisphosphate aldolase from plasmodium2 falciparum in complex with trap-tail determined at 2.4 angstrom3 resolution 103 d1m2ia_ not modelled 20.7 24 Fold:Cytochrome b5-like heme/steroid binding domain Superfamily:Cytochrome b5-like heme/steroid binding domain Family:Cytochrome b5 104 d1vk9a_ not modelled 20.7 12 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Hypothetical protein TM1506 105 c3lwdA_ not modelled 20.4 15 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of putative 6-phosphogluconolactonase (yp_574786.1)2 from chromohalobacter salexigens dsm 3043 at 1.88 a resolution 106 d1a5ca_ not modelled 20.4 20 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 107 d1cxya_ not modelled 20.3 18 Fold:Cytochrome b5-like heme/steroid binding domain Superfamily:Cytochrome b5-like heme/steroid binding domain Family:Cytochrome b5

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0