Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	N	L	T	Y	L	Q	G	Y	P	E	Q	L	L	S	Q	V	R	T	L	I	N	E	Q	R	L	G	D	V	L	A	K	R	Y	P	G	T	H	D	Y	A	T	D	K	A	L	W	Q	Y	T	Q	D	L	K	N	Q	F	L	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?															?	?			?	?												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		N	A	P	P	I	N	K	V	M	Y	D	N	K	I	H	V	L	K	N	A	L	G	L	H	T	A	V	S	R	V	Q	G	G	K	L	K	A	K	V	E	I	R	V	A	T	V	F	R	N	A	P	E	P	F	L	R	M	I	V	V
Secondary structure
SS confidence
Disorder																?										?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
Sequence		H	E	L	A	H	L	K	E	K	E	H	N	K	A	F	Y	Q	L	C	C	H	M	E	P	Q	Y	H	Q	L	E	F	D	T	R	L	W	L	T	Q	L	S	L	G	Q	N	K	I
Secondary structure
SS confidence
Disorder																																										?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3cqb chain B Region: 93 - 130 Aligned: 38 Modelled: 38 Confidence: 94.8% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:probable protease htpx homolog; PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633 Phyre2 PDB 3c37 chain B Region: 23 - 139 Aligned: 105 Modelled: 100 Confidence: 94.5% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:peptidase, m48 family; PDBTitle: x-ray structure of the putative zn-dependent peptidase q74d82 at the2 resolution 1.7 a. northeast structural genomics consortium target3 gsr143a Phyre2 PDB 3dtk chain A Region: 46 - 160 Aligned: 108 Modelled: 115 Confidence: 92.9% Identity: 14% PDB header:gene regulation Chain: A: PDB Molecule:irre protein; PDBTitle: crystal structure of the irre protein, a central regulator2 of dna damage repair in deinococcaceae Phyre2 PDB 1atl chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 85.9% Identity: 23% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Reprolysin-like Phyre2 PDB 1bsw chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 85.8% Identity: 18% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Reprolysin-like Phyre2 PDB 1qua chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 83.4% Identity: 18% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Reprolysin-like Phyre2 PDB 1r55 chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 80.4% Identity: 20% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Reprolysin-like Phyre2 PDB 1nd1 chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 80.4% Identity: 20% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Reprolysin-like Phyre2 PDB 4aig chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 80.1% Identity: 15% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Reprolysin-like Phyre2 PDB 1yp1 chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 79.6% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:fii; PDBTitle: crystal structure of a non-hemorrhagic fibrin(ogen)olytic2 metalloproteinase from venom of agkistrodon acutus Phyre2 PDB 1kuf chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 77.1% Identity: 23% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Reprolysin-like Phyre2 PDB 3k7l chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 76.8% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:atragin; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins Phyre2 PDB 3cmn chain A Region: 111 - 162 Aligned: 52 Modelled: 52 Confidence: 75.4% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of a putative hydrolase with a novel fold2 from chloroflexus aurantiacus Phyre2 PDB 2xdt chain A Region: 57 - 130 Aligned: 74 Modelled: 74 Confidence: 74.2% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the soluble domain of human2 endoplasmic reticulum aminopeptidase 1 erap1 Phyre2 PDB 1wni chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 73.9% Identity: 20% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Reprolysin-like Phyre2 PDB 3cmn chain A domain 1 Region: 111 - 162 Aligned: 52 Modelled: 52 Confidence: 73.6% Identity: 23% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Caur0242-like Phyre2 PDB 2gtq chain A Region: 57 - 130 Aligned: 74 Modelled: 74 Confidence: 72.9% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis Phyre2 PDB 2i47 chain A Region: 110 - 132 Aligned: 23 Modelled: 23 Confidence: 72.6% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:adam 17; PDBTitle: crystal structure of catalytic domain of tace with inhibitor Phyre2 PDB 1eak chain A Region: 91 - 132 Aligned: 29 Modelled: 29 Confidence: 72.4% Identity: 21% PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:72 kda type iv collagenase; PDBTitle: catalytic domain of prommp-2 e404q mutant Phyre2 PDB 2e3x chain A Region: 92 - 132 Aligned: 40 Modelled: 41 Confidence: 72.1% Identity: 23% PDB header:hydrolase, blood clotting, toxin Chain: A: PDB Molecule:coagulation factor x-activating enzyme heavy chain; PDBTitle: crystal structure of russell's viper venom metalloproteinase Phyre2 1 c3cqbB_ 2 c3c37B_ 3 c3dtkA_ 4 d1atla_ 5 d1bswa_ 6 d1quaa_ 7 d1r55a_ 8 d1nd1a_ 9 d4aiga_ 10 c1yp1A_ 11 d1kufa_ 12 c3k7lA_ 13 c3cmnA_ 14 c2xdtA_ 15 d1wnia_ 16 d3cmna1 17 c2gtqA_ 18 c2i47A_ 19 c1eakA_ 20 c2e3xA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3cqbB_ 94.8 16 PDB header:hydrolase Chain: B: PDB Molecule:probable protease htpx homolog; PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633 2 c3c37B_ 94.5 19 PDB header:hydrolase Chain: B: PDB Molecule:peptidase, m48 family; PDBTitle: x-ray structure of the putative zn-dependent peptidase q74d82 at the2 resolution 1.7 a. northeast structural genomics consortium target3 gsr143a 3 c3dtkA_ 92.9 14 PDB header:gene regulation Chain: A: PDB Molecule:irre protein; PDBTitle: crystal structure of the irre protein, a central regulator2 of dna damage repair in deinococcaceae 4 d1atla_ 85.9 23 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 5 d1bswa_ 85.8 18 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 6 d1quaa_ 83.4 18 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 7 d1r55a_ 80.4 20 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 8 d1nd1a_ 80.4 20 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 9 d4aiga_ 80.1 15 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 10 c1yp1A_ 79.6 25 PDB header:hydrolase Chain: A: PDB Molecule:fii; PDBTitle: crystal structure of a non-hemorrhagic fibrin(ogen)olytic2 metalloproteinase from venom of agkistrodon acutus 11 d1kufa_ 77.1 23 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 12 c3k7lA_ 76.8 18 PDB header:hydrolase Chain: A: PDB Molecule:atragin; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins 13 c3cmnA_ 75.4 23 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of a putative hydrolase with a novel fold2 from chloroflexus aurantiacus 14 c2xdtA_ 74.2 15 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the soluble domain of human2 endoplasmic reticulum aminopeptidase 1 erap1 15 d1wnia_ 73.9 20 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 16 d3cmna1 73.6 23 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Caur0242-like 17 c2gtqA_ 72.9 14 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis 18 c2i47A_ 72.6 26 PDB header:hydrolase Chain: A: PDB Molecule:adam 17; PDBTitle: crystal structure of catalytic domain of tace with inhibitor 19 c1eakA_ 72.4 21 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:72 kda type iv collagenase; PDBTitle: catalytic domain of prommp-2 e404q mutant 20 c2e3xA_ 72.1 23 PDB header:hydrolase, blood clotting, toxin Chain: A: PDB Molecule:coagulation factor x-activating enzyme heavy chain; PDBTitle: crystal structure of russell's viper venom metalloproteinase 21 d2i47a1 not modelled 72.1 26 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TNF-alpha converting enzyme, TACE, catalytic domain 22 c3ebhA_ not modelled 71.8 14 PDB header:hydrolase inhibitor Chain: A: PDB Molecule:m1 family aminopeptidase; PDBTitle: structure of the m1 alanylaminopeptidase from malaria complexed with2 bestatin 23 c3b37A_ not modelled 71.4 15 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of e. coli aminopeptidase n in complex with tyrosine 24 c3dl1A_ not modelled 70.8 40 PDB header:hydrolase Chain: A: PDB Molecule:putative metal-dependent hydrolase; PDBTitle: crystal structure of a putative metal-dependent hydrolase2 (yp_001336084.1) from klebsiella pneumoniae subsp. pneumoniae mgh3 78578 at 2.20 a resolution 25 c3g5cA_ not modelled 69.5 18 PDB header:membrane protein Chain: A: PDB Molecule:adam 22; PDBTitle: structural and biochemical studies on the ectodomain of human adam22 26 c2rjqA_ not modelled 68.8 22 PDB header:hydrolase Chain: A: PDB Molecule:adamts-5; PDBTitle: crystal structure of adamts5 with inhibitor bound 27 c2erpA_ not modelled 66.8 15 PDB header:toxin Chain: A: PDB Molecule:vascular apoptosis-inducing protein 1; PDBTitle: crystal structure of vascular apoptosis-inducing protein-1(inhibitor-2 bound form) 28 c3k7nA_ not modelled 66.6 18 PDB header:hydrolase Chain: A: PDB Molecule:k-like; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins 29 d1rm8a_ not modelled 62.4 44 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 30 c3mdjB_ not modelled 62.3 16 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: er aminopeptidase, erap1, bound to the zinc aminopeptidase inhibitor,2 bestatin 31 d1xuca1 not modelled 61.2 28 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 32 d3e11a1 not modelled 60.4 44 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TTHA0227-like 33 d1k7ia2 not modelled 60.4 18 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 34 c2l0rA_ not modelled 59.5 23 PDB header:hydrolase,toxin Chain: A: PDB Molecule:lethal factor; PDBTitle: conformational dynamics of the anthrax lethal factor catalytic center 35 d1hv5a_ not modelled 59.1 28 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 36 d1bqqm_ not modelled 58.8 39 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 37 c2dw1B_ not modelled 58.6 18 PDB header:apoptosis, toxin Chain: B: PDB Molecule:catrocollastatin; PDBTitle: crystal structure of vap2 from crotalus atrox venom (form 2-2 crystal) 38 d1sata2 not modelled 58.1 19 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 39 c2v4bB_ not modelled 57.6 31 PDB header:hydrolase Chain: B: PDB Molecule:adamts-1; PDBTitle: crystal structure of human adamts-1 catalytic domain and2 cysteine-rich domain (apo-form) 40 c3qnfA_ not modelled 57.2 16 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the open state of human endoplasmic reticulum2 aminopeptidase 1 erap1 41 d2ejqa1 not modelled 56.9 35 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TTHA0227-like 42 c1slmA_ not modelled 56.3 28 PDB header:hydrolase Chain: A: PDB Molecule:stromelysin-1; PDBTitle: crystal structure of fibroblast stromelysin-1: the c-truncated human2 proenzyme 43 d1qiba_ not modelled 56.2 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 44 c2xs4A_ not modelled 55.7 39 PDB header:hydrolase Chain: A: PDB Molecule:karilysin protease; PDBTitle: structure of karilysin catalytic mmp domain in complex with2 magnesium 45 c2rjpC_ not modelled 55.6 25 PDB header:hydrolase Chain: C: PDB Molecule:adamts-4; PDBTitle: crystal structure of adamts4 with inhibitor bound 46 c3b8zB_ not modelled 54.3 38 PDB header:hydrolase Chain: B: PDB Molecule:protein adamts-5; PDBTitle: high resolution crystal structure of the catalytic domain2 of adamts-5 (aggrecanase-2) 47 d1q3aa_ not modelled 53.6 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 48 d1hfca_ not modelled 53.5 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 49 d1mmqa_ not modelled 52.6 28 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 50 d1lmla_ not modelled 52.5 21 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Leishmanolysin 51 d1cgla_ not modelled 51.7 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 52 d1i76a_ not modelled 51.3 28 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 53 d2ovxa1 not modelled 50.9 22 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 54 d1hy7a_ not modelled 50.9 28 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 55 c1l6jA_ not modelled 50.7 21 PDB header:hydrolase Chain: A: PDB Molecule:matrix metalloproteinase-9; PDBTitle: crystal structure of human matrix metalloproteinase mmp92 (gelatinase b). 56 d1hova_ not modelled 50.6 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 57 c2xhqA_ not modelled 50.4 20 PDB header:hydrolase Chain: A: PDB Molecule:archaemetzincin; PDBTitle: crystal structure of archaemetzincin (amza) from archaeoglobus2 fulgidus at 1.45 a resolution 58 d1cxva_ not modelled 50.3 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 59 d1y93a1 not modelled 50.2 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 60 c2jsdA_ not modelled 49.7 28 PDB header:hydrolase Chain: A: PDB Molecule:matrix metalloproteinase-20; PDBTitle: solution structure of mmp20 complexed with nngh 61 c1su3A_ not modelled 47.3 33 PDB header:hydrolase Chain: A: PDB Molecule:interstitial collagenase; PDBTitle: x-ray structure of human prommp-1: new insights into2 collagenase action 62 c3se6A_ not modelled 46.3 26 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 2; PDBTitle: crystal structure of the human endoplasmic reticulum aminopeptidase 2 63 c1z5hB_ not modelled 45.6 21 PDB header:hydrolase Chain: B: PDB Molecule:tricorn protease interacting factor f3; PDBTitle: crystal structures of the tricorn interacting factor f32 from thermoplasma acidophilum 64 d1npca_ not modelled 45.6 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 65 d1eaka2 not modelled 45.4 28 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 66 d1kjpa_ not modelled 43.6 63 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 67 d1kapp2 not modelled 43.2 25 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 68 c2cltB_ not modelled 42.8 28 PDB header:hydrolase Chain: B: PDB Molecule:interstitial collagenase; PDBTitle: crystal structure of the active form (full-length) of human2 fibroblast collagenase. 69 d1bqba_ not modelled 41.7 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 70 c3nqxA_ not modelled 40.8 38 PDB header:hydrolase Chain: A: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of vibriolysin mcp-02 mature enzyme, a zinc2 metalloprotease from m4 family 71 c3nqzB_ not modelled 40.5 38 PDB header:hydrolase Chain: B: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of the autoprocessed vibriolysin mcp-02 with e369a2 mutation 72 d1g9ka2 not modelled 40.3 25 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 73 c2xpyA_ not modelled 40.2 38 PDB header:hydrolase Chain: A: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: structure of native leukotriene a4 hydrolase from saccharomyces2 cerevisiae 74 c2vqxA_ not modelled 40.1 63 PDB header:hydrolase Chain: A: PDB Molecule:metalloproteinase; PDBTitle: precursor of protealysin, metalloproteinase from serratia2 proteamaculans. 75 d1fbla2 not modelled 38.9 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 76 c2x7mA_ not modelled 38.3 36 PDB header:hydrolase Chain: A: PDB Molecule:archaemetzincin; PDBTitle: crystal structure of archaemetzincin (amza) from methanopyrus2 kandleri at 1.5 a resolution 77 d3b7sa3 not modelled 38.3 19 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Leukotriene A4 hydrolase catalytic domain 78 d1eb6a_ not modelled 38.2 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Fungal zinc peptidase 79 c3ciaA_ not modelled 38.2 38 PDB header:hydrolase Chain: A: PDB Molecule:cold-active aminopeptidase; PDBTitle: crystal structure of cold-aminopeptidase from colwellia2 psychrerythraea 80 c3b7uX_ not modelled 38.1 23 PDB header:hydrolase Chain: X: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: leukotriene a4 hydrolase complexed with kelatorphan 81 c3p24C_ not modelled 37.8 33 PDB header:hydrolase Chain: C: PDB Molecule:bft-3; PDBTitle: structure of profragilysin-3 from bacteroides fragilis 82 c3edhA_ not modelled 36.7 57 PDB header:hydrolase Chain: A: PDB Molecule:bone morphogenetic protein 1; PDBTitle: crystal structure of bone morphogenetic protein 1 protease2 domain in complex with partially bound dmso 83 c3lmcA_ not modelled 35.7 36 PDB header:hydrolase Chain: A: PDB Molecule:peptidase, zinc-dependent; PDBTitle: crystal structure of zinc-dependent peptidase from methanocorpusculum2 labreanum (strain z), northeast structural genomics consortium target3 mur16 84 d1u4ga_ not modelled 35.5 38 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 85 c3ba0A_ not modelled 31.4 33 PDB header:hydrolase Chain: A: PDB Molecule:macrophage metalloelastase; PDBTitle: crystal structure of full-length human mmp-12 86 d1asta_ not modelled 30.6 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Astacin 87 d1g12a_ not modelled 29.6 44 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Fungal zinc peptidase 88 c1jiwP_ not modelled 27.7 25 PDB header:hydrolase/hyrolase inhibitor Chain: P: PDB Molecule:alkaline metalloproteinase; PDBTitle: crystal structure of the apr-aprin complex 89 c3lq0A_ not modelled 26.4 29 PDB header:hydrolase Chain: A: PDB Molecule:proastacin; PDBTitle: zymogen structure of crayfish astacin metallopeptidase 90 d1j7na2 not modelled 26.2 20 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Anthrax toxin lethal factor, N- and C-terminal domains 91 c3lqbA_ not modelled 25.2 38 PDB header:hydrolase Chain: A: PDB Molecule:loc792177 protein; PDBTitle: crystal structure of the hatching enzyme zhe1 from the zebrafish danio2 rerio 92 c2x3bB_ not modelled 24.6 44 PDB header:hydrolase Chain: B: PDB Molecule:toxic extracellular endopeptidase; PDBTitle: asap1 inactive mutant e294a, an extracellular toxic zinc2 metalloendopeptidase 93 c1om8A_ not modelled 24.6 25 PDB header:hydrolase Chain: A: PDB Molecule:serralysin; PDBTitle: crystal structure of a cold adapted alkaline protease from pseudomonas2 tac ii 18, co-crystallyzed with 10 mm edta 94 c3b4rB_ not modelled 24.1 50 PDB header:hydrolase Chain: B: PDB Molecule:putative zinc metalloprotease mj0392; PDBTitle: site-2 protease from methanocaldococcus jannaschii 95 d1wh4a_ not modelled 19.5 13 Fold:DEATH domain Superfamily:DEATH domain Family:DEATH domain, DD 96 c1gxdA_ not modelled 18.7 28 PDB header:hydrolase Chain: A: PDB Molecule:72 kda type iv collagenase; PDBTitle: prommp-2/timp-2 complex 97 d1oz9a_ not modelled 17.7 18 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Predicted metal-dependent hydrolase 98 c1satA_ not modelled 13.9 25 PDB header:hydrolase (serine protease) Chain: A: PDB Molecule:serratia protease; PDBTitle: crystal structure of the 50 kda metallo protease from s.2 marcescens 99 c2kmgA_ not modelled 12.2 17 PDB header:gene regulation Chain: A: PDB Molecule:klca; PDBTitle: the structure of the klca and ardb proteins show a novel2 fold and antirestriction activity against type i dna3 restriction systems in vivo but not in vitro

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0