Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	I	Y	L	V	G	G	A	V	R	D	A	L	L	G	L	P	V	K	D	R	D	W	V	V	V	G	S	T	P	Q	E	M	L	D	A	G	Y	Q	Q	V	G	R	D	F	P	V	F	L	H	P	Q	T	H	E	E	Y	A	L
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	R	T	E	R	K	S	G	S	G	Y	T	G	F	T	C	Y	A	A	P	D	V	T	L	E	D	D	L	K	R	R	D	L	T	I	N	A	L	A	Q	D	D	N	G	E	I	I	D	P	Y	N	G	L	G	D	L	Q	N	R	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	R	H	V	S	P	A	F	G	E	D	P	L	R	V	L	R	V	A	R	F	A	A	R	Y	A	H	L	G	F	R	I	A	D	E	T	L	A	L	M	R	E	M	T	H	A	G	E	L	E	H	L	T	P	E	R	V	W	K	E
Secondary structure
SS confidence
Disorder																																																?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	E	S	A	L	T	T	R	N	P	Q	V	F	F	Q	V	L	R	D	C	G	A	L	R	V	L	F	P	E	I	D	A	L	F	G	V	P	A	P	A	K	W	H	P	E	I	D	T	G	I	H	T	L	M	T	L	S	M	A	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		M	L	S	P	Q	V	D	V	R	F	A	T	L	C	H	D	L	G	K	G	L	T	P	P	E	L	W	P	R	H	H	G	H	G	P	A	G	V	K	L	V	E	Q	L	C	Q	R	L	R	V	P	N	E	I	R	D	L	A	R	L
Secondary structure
SS confidence
Disorder																				?																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	A	E	F	H	D	L	I	H	T	F	P	M	L	N	P	K	T	I	V	K	L	F	D	S	I	D	A	W	R	K	P	Q	R	V	E	Q	L	A	L	T	S	E	A	D	V	R	G	R	T	G	F	E	S	A	D	Y	P	Q	G
Secondary structure
SS confidence
Disorder											?	?	?		?																																	?	?	?	?	?	?		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.
Sequence		R	W	L	R	E	A	W	E	V	A	Q	S	V	P	T	K	A	V	V	E	A	G	F	K	G	V	E	I	R	E	E	L	T	R	R	R	I	A	A	V	A	S	W	K	E	Q	R	C	P	K	P	E
Secondary structure
SS confidence
Disorder																?						?																									?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1miy chain B Region: 1 - 401 Aligned: 344 Modelled: 367 Confidence: 100.0% Identity: 26% PDB header:translation, transferase Chain: B: PDB Molecule:trna cca-adding enzyme; PDBTitle: crystal structure of bacillus stearothermophilus cca-adding enzyme in2 complex with ctp Phyre2 PDB 1vfg chain B Region: 1 - 387 Aligned: 334 Modelled: 368 Confidence: 100.0% Identity: 24% PDB header:transferase/rna Chain: B: PDB Molecule:poly a polymerase; PDBTitle: crystal structure of trna nucleotidyltransferase complexed2 with a primer trna and an incoming atp analog Phyre2 PDB 3h37 chain B Region: 1 - 401 Aligned: 349 Modelled: 379 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: B: PDB Molecule:trna nucleotidyl transferase-related protein; PDBTitle: the structure of cca-adding enzyme apo form i Phyre2 PDB 3aqn chain A Region: 1 - 359 Aligned: 332 Modelled: 357 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: A: PDB Molecule:poly(a) polymerase; PDBTitle: complex structure of bacterial protein (apo form ii) Phyre2 PDB 1ou5 chain A Region: 1 - 315 Aligned: 262 Modelled: 265 Confidence: 100.0% Identity: 25% PDB header:translation, transferase Chain: A: PDB Molecule:trna cca-adding enzyme; PDBTitle: crystal structure of human cca-adding enzyme Phyre2 PDB 1miw chain A domain 1 Region: 120 - 402 Aligned: 236 Modelled: 247 Confidence: 100.0% Identity: 22% Fold: Poly A polymerase C-terminal region-like Superfamily: Poly A polymerase C-terminal region-like Family: Poly A polymerase C-terminal region-like Phyre2 PDB 1miw chain A domain 2 Region: 1 - 119 Aligned: 109 Modelled: 119 Confidence: 100.0% Identity: 36% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Poly A polymerase head domain-like Phyre2 PDB 1vfg chain A domain 2 Region: 1 - 119 Aligned: 108 Modelled: 108 Confidence: 100.0% Identity: 38% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Poly A polymerase head domain-like Phyre2 PDB 1ou5 chain A domain 2 Region: 1 - 119 Aligned: 104 Modelled: 105 Confidence: 100.0% Identity: 29% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Poly A polymerase head domain-like Phyre2 PDB 1vfg chain A domain 1 Region: 120 - 372 Aligned: 212 Modelled: 234 Confidence: 100.0% Identity: 18% Fold: Poly A polymerase C-terminal region-like Superfamily: Poly A polymerase C-terminal region-like Family: Poly A polymerase C-terminal region-like Phyre2 PDB 1ou5 chain A domain 1 Region: 120 - 315 Aligned: 155 Modelled: 160 Confidence: 99.9% Identity: 23% Fold: Poly A polymerase C-terminal region-like Superfamily: Poly A polymerase C-terminal region-like Family: Poly A polymerase C-terminal region-like Phyre2 PDB 2qgs chain A domain 1 Region: 229 - 406 Aligned: 159 Modelled: 175 Confidence: 97.3% Identity: 13% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 2pq7 chain A domain 1 Region: 203 - 305 Aligned: 99 Modelled: 101 Confidence: 97.2% Identity: 17% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 3djb chain A domain 1 Region: 229 - 302 Aligned: 64 Modelled: 74 Confidence: 96.6% Identity: 22% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 3b57 chain A domain 1 Region: 229 - 305 Aligned: 62 Modelled: 62 Confidence: 95.5% Identity: 13% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 3m5f chain A Region: 247 - 305 Aligned: 59 Modelled: 59 Confidence: 94.4% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:metal dependent phosphohydrolase; PDBTitle: structure of mj0384, a cas3 protein from methanocaldococcus jannaschii Phyre2 PDB 3dto chain A domain 1 Region: 229 - 305 Aligned: 62 Modelled: 62 Confidence: 94.3% Identity: 18% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 2la3 chain A Region: 2 - 123 Aligned: 106 Modelled: 107 Confidence: 93.7% Identity: 24% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the nmr structure of the protein np_344798.1 reveals a cca-adding2 enzyme head domain Phyre2 PDB 1u6z chain A domain 1 Region: 247 - 305 Aligned: 51 Modelled: 59 Confidence: 91.8% Identity: 16% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: Ppx associated domain Phyre2 PDB 2pjq chain A domain 1 Region: 229 - 325 Aligned: 80 Modelled: 80 Confidence: 91.7% Identity: 14% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 1 c1miyB_ 2 c1vfgB_ 3 c3h37B_ 4 c3aqnA_ 5 c1ou5A_ 6 d1miwa1 7 d1miwa2 8 d1vfga2 9 d1ou5a2 10 d1vfga1 11 d1ou5a1 12 d2qgsa1 13 d2pq7a1 14 d3djba1 15 d3b57a1 16 c3m5fA_ 17 d3dtoa1 18 c2la3A_ 19 d1u6za1 20 d2pjqa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1miyB_ 100.0 26 PDB header:translation, transferase Chain: B: PDB Molecule:trna cca-adding enzyme; PDBTitle: crystal structure of bacillus stearothermophilus cca-adding enzyme in2 complex with ctp 2 c1vfgB_ 100.0 24 PDB header:transferase/rna Chain: B: PDB Molecule:poly a polymerase; PDBTitle: crystal structure of trna nucleotidyltransferase complexed2 with a primer trna and an incoming atp analog 3 c3h37B_ 100.0 23 PDB header:transferase Chain: B: PDB Molecule:trna nucleotidyl transferase-related protein; PDBTitle: the structure of cca-adding enzyme apo form i 4 c3aqnA_ 100.0 25 PDB header:transferase Chain: A: PDB Molecule:poly(a) polymerase; PDBTitle: complex structure of bacterial protein (apo form ii) 5 c1ou5A_ 100.0 25 PDB header:translation, transferase Chain: A: PDB Molecule:trna cca-adding enzyme; PDBTitle: crystal structure of human cca-adding enzyme 6 d1miwa1 100.0 22 Fold:Poly A polymerase C-terminal region-like Superfamily:Poly A polymerase C-terminal region-like Family:Poly A polymerase C-terminal region-like 7 d1miwa2 100.0 36 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Poly A polymerase head domain-like 8 d1vfga2 100.0 38 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Poly A polymerase head domain-like 9 d1ou5a2 100.0 29 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Poly A polymerase head domain-like 10 d1vfga1 100.0 18 Fold:Poly A polymerase C-terminal region-like Superfamily:Poly A polymerase C-terminal region-like Family:Poly A polymerase C-terminal region-like 11 d1ou5a1 99.9 23 Fold:Poly A polymerase C-terminal region-like Superfamily:Poly A polymerase C-terminal region-like Family:Poly A polymerase C-terminal region-like 12 d2qgsa1 97.3 13 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 13 d2pq7a1 97.2 17 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 14 d3djba1 96.6 22 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 15 d3b57a1 95.5 13 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 16 c3m5fA_ 94.4 12 PDB header:hydrolase Chain: A: PDB Molecule:metal dependent phosphohydrolase; PDBTitle: structure of mj0384, a cas3 protein from methanocaldococcus jannaschii 17 d3dtoa1 94.3 18 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 18 c2la3A_ 93.7 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the nmr structure of the protein np_344798.1 reveals a cca-adding2 enzyme head domain 19 d1u6za1 91.8 16 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:Ppx associated domain 20 d2pjqa1 91.7 14 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 21 d2fcla1 not modelled 91.4 19 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:TM1012-like 22 c2q14A_ not modelled 90.9 19 PDB header:hydrolase Chain: A: PDB Molecule:phosphohydrolase; PDBTitle: crystal structure of phosphohydrolase (bt4208) from bacteroides2 thetaiotaomicron vpi-5482 at 2.20 a resolution 23 c2o08B_ not modelled 90.7 28 PDB header:hydrolase Chain: B: PDB Molecule:bh1327 protein; PDBTitle: crystal structure of a putative hd superfamily hydrolase (bh1327) from2 bacillus halodurans at 1.90 a resolution 24 c3ccgA_ not modelled 88.9 32 PDB header:hydrolase Chain: A: PDB Molecule:hd superfamily hydrolase; PDBTitle: crystal structure of predicted hd superfamily hydrolase involved in2 nad metabolism (np_347894.1) from clostridium acetobutylicum at 1.503 a resolution 25 c3skdA_ not modelled 87.7 18 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein tthb187; PDBTitle: crystal structure of the thermus thermophilus cas3 hd domain in the2 presence of ni2+ 26 c3u1nC_ not modelled 86.6 25 PDB header:hydrolase Chain: C: PDB Molecule:sam domain and hd domain-containing protein 1; PDBTitle: structure of the catalytic core of human samhd1 27 c2ogiA_ not modelled 85.9 28 PDB header:hydrolase Chain: A: PDB Molecule:hypothetical protein sag1661; PDBTitle: crystal structure of a putative metal dependent phosphohydrolase2 (sag1661) from streptococcus agalactiae serogroup v at 1.85 a3 resolution 28 c3gw7A_ not modelled 85.5 14 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein yedj; PDBTitle: crystal structure of a metal-dependent phosphohydrolase2 with conserved hd domain (yedj) from escherichia coli in3 complex with nickel ions. northeast structural genomics4 consortium target er63 29 c2floA_ not modelled 84.9 15 PDB header:hydrolase Chain: A: PDB Molecule:exopolyphosphatase; PDBTitle: crystal structure of exopolyphosphatase (ppx) from e. coli o157:h7 30 d2o6ia1 not modelled 82.9 23 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 31 c2o6iA_ not modelled 82.9 23 PDB header:hydrolase Chain: A: PDB Molecule:hd domain protein; PDBTitle: structure of an enterococcus faecalis hd domain phosphohydrolase 32 d2gz4a1 not modelled 70.6 12 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 33 c3kq5A_ not modelled 66.0 7 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical cytosolic protein; PDBTitle: crystal structure of an uncharacterized protein from coxiella burnetii 34 c3hi0B_ not modelled 61.4 10 PDB header:hydrolase Chain: B: PDB Molecule:putative exopolyphosphatase; PDBTitle: crystal structure of putative exopolyphosphatase (17739545) from2 agrobacterium tumefaciens str. c58 (dupont) at 2.30 a resolution 35 c2dqbB_ not modelled 61.3 22 PDB header:hydrolase, dna binding protein Chain: B: PDB Molecule:deoxyguanosinetriphosphate triphosphohydrolase, putative; PDBTitle: crystal structure of dntp triphosphohydrolase from thermus2 thermophilus hb8, which is homologous to dgtp triphosphohydrolase 36 c2pgsA_ not modelled 54.9 29 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyguanosinetriphosphate triphosphohydrolase; PDBTitle: crystal structure of a putative deoxyguanosinetriphosphate2 triphosphohydrolase from pseudomonas syringae pv. phaseolicola 1448a 37 c3lmaC_ not modelled 44.5 19 PDB header:membrane protein Chain: C: PDB Molecule:stage v sporulation protein ad (spovad); PDBTitle: crystal structure of the stage v sporulation protein ad2 (spovad) from bacillus licheniformis. northeast structural3 genomics consortium target bir6. 38 c3hc1A_ not modelled 43.5 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized hdod domain protein; PDBTitle: crystal structure of hdod domain protein with unknown function2 (np_953345.1) from geobacter sulfurreducens at 1.90 a resolution 39 c3m1tA_ not modelled 41.1 14 PDB header:hydrolase Chain: A: PDB Molecule:putative phosphohydrolase; PDBTitle: crystal structure of putative phosphohydrolase (yp_929327.1) from2 shewanella amazonensis sb2b at 1.62 a resolution 40 d1vqra_ not modelled 40.9 12 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:modified HD domain 41 d1ylqa1 not modelled 38.8 30 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Catalytic subunit of bi-partite nucleotidyltransferase 42 c2w9mB_ not modelled 34.1 21 PDB header:dna replication Chain: B: PDB Molecule:polymerase x; PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans 43 d2ibna1 not modelled 31.2 16 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:MioX-like 44 d2heka1 not modelled 30.7 20 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 45 c2huoA_ not modelled 26.1 26 PDB header:oxidoreductase Chain: A: PDB Molecule:inositol oxygenase; PDBTitle: crystal structure of mouse myo-inositol oxygenase in complex with2 substrate 46 d3bxda1 not modelled 26.1 26 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:MioX-like 47 d1jmsa4 not modelled 21.1 17 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:DNA polymerase beta-like 48 d1wota_ not modelled 20.1 18 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Catalytic subunit of bi-partite nucleotidyltransferase 49 c3bg2A_ not modelled 19.6 23 PDB header:hydrolase Chain: A: PDB Molecule:dgtp triphosphohydrolase; PDBTitle: crystal structure of deoxyguanosinetriphosphate triphosphohydrolase2 from flavobacterium sp. med217 50 c3k1rB_ not modelled 19.4 24 PDB header:structural protein Chain: B: PDB Molecule:usher syndrome type-1g protein; PDBTitle: structure of harmonin npdz1 in complex with the sam-pbm of2 sans 51 d1r89a2 not modelled 18.6 13 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Archaeal tRNA CCA-adding enzyme catalytic domain 52 d2bcqa3 not modelled 17.2 10 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:DNA polymerase beta-like 53 d2b7oa1 not modelled 17.0 38 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class-II DAHP synthetase 54 d1no5a_ not modelled 15.8 18 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Catalytic subunit of bi-partite nucleotidyltransferase 55 d2dula1 not modelled 15.1 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:TRM1-like 56 d1bgfa_ not modelled 12.8 22 Fold:Transcription factor STAT-4 N-domain Superfamily:Transcription factor STAT-4 N-domain Family:Transcription factor STAT-4 N-domain 57 c3riuC_ not modelled 12.7 22 PDB header:hydrolase Chain: C: PDB Molecule:translin associated factor x, isoform b; PDBTitle: crystal structure of drosophila hexameric c3po formed by truncated2 translin and trax 58 c2bcuA_ not modelled 12.2 14 PDB header:transferase, lyase/dna Chain: A: PDB Molecule:dna polymerase lambda; PDBTitle: dna polymerase lambda in complex with a dna duplex2 containing an unpaired damp and a t:t mismatch 59 c2ihmA_ not modelled 11.8 18 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase mu; PDBTitle: polymerase mu in ternary complex with gapped 11mer dna2 duplex and bound incoming nucleotide 60 d1vola2 not modelled 11.4 17 Fold:Cyclin-like Superfamily:Cyclin-like Family:Transcription factor IIB (TFIIB), core domain 61 d1es6a1 not modelled 11.3 45 Fold:EV matrix protein Superfamily:EV matrix protein Family:EV matrix protein 62 d2gmwa1 not modelled 11.0 22 Fold:HAD-like Superfamily:HAD-like Family:Histidinol phosphatase-like 63 c3esqA_ not modelled 11.0 22 PDB header:hydrolase Chain: A: PDB Molecule:d,d-heptose 1,7-bisphosphate phosphatase; PDBTitle: crystal structure of calcium-bound d,d-heptose 1.7-2 bisphosphate phosphatase from e. coli 64 c2r8qA_ not modelled 10.0 21 PDB header:hydrolase Chain: A: PDB Molecule:class i phosphodiesterase pdeb1; PDBTitle: structure of lmjpdeb1 in complex with ibmx 65 d1t3ta4 not modelled 9.3 44 Fold:Bacillus chorismate mutase-like Superfamily:PurM N-terminal domain-like Family:PurM N-terminal domain-like 66 d2fmpa3 not modelled 9.2 14 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:DNA polymerase beta-like 67 c3ndcB_ not modelled 9.2 29 PDB header:transferase Chain: B: PDB Molecule:precorrin-4 c(11)-methyltransferase; PDBTitle: crystal structure of precorrin-4 c11-methyltransferase from2 rhodobacter capsulatus 68 d1vk3a1 not modelled 9.1 67 Fold:Bacillus chorismate mutase-like Superfamily:PurM N-terminal domain-like Family:PurM N-terminal domain-like 69 c1h2dA_ not modelled 9.1 45 PDB header:virus/viral protein Chain: A: PDB Molecule:matrix protein vp40; PDBTitle: ebola virus matrix protein vp40 n-terminal domain in2 complex with rna (low-resolution vp40[31-212] variant). 70 c2cqzA_ not modelled 9.1 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:177aa long hypothetical protein; PDBTitle: crystal structure of ph0347 protein from pyrococcus horikoshii ot3 71 d1h2ca_ not modelled 9.1 45 Fold:EV matrix protein Superfamily:EV matrix protein Family:EV matrix protein 72 d1jqra_ not modelled 8.8 18 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:DNA polymerase beta-like 73 c2rffA_ not modelled 8.6 26 PDB header:transferase Chain: A: PDB Molecule:putative nucleotidyltransferase; PDBTitle: crystal structure of a putative nucleotidyltransferase2 (np_343093.1) from sulfolobus solfataricus at 1.40 a3 resolution 74 d1uqva_ not modelled 8.6 4 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:SAM (sterile alpha motif) domain 75 c1b0nB_ not modelled 7.8 32 PDB header:transcription regulator Chain: B: PDB Molecule:protein (sini protein); PDBTitle: sinr protein/sini protein complex 76 d1b0nb_ not modelled 7.8 32 Fold:Dimerisation interlock Superfamily:SinR repressor dimerisation domain-like Family:SinR repressor dimerisation domain-like 77 d1g60a_ not modelled 7.6 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase 78 d1eg2a_ not modelled 7.4 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase 79 d1vola1 not modelled 7.4 12 Fold:Cyclin-like Superfamily:Cyclin-like Family:Transcription factor IIB (TFIIB), core domain 80 c3ljvA_ not modelled 7.4 9 PDB header:transcription Chain: A: PDB Molecule:mmoq response regulator; PDBTitle: crystal structure of mmoq response regulator (fragment 29-302) from2 methylococcus capsulatus str. bath, northeast structural genomics3 consortium target mcr175m 81 c2zifB_ not modelled 7.3 25 PDB header:transferase Chain: B: PDB Molecule:putative modification methylase; PDBTitle: crystal structure of ttha0409, putative dna modification2 methylase from thermus thermophilus hb8- complexed with s-3 adenosyl-l-methionine 82 d2vana2 not modelled 7.1 21 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:DNA polymerase beta-like 83 c1xotB_ not modelled 6.3 14 PDB header:hydrolase Chain: B: PDB Molecule:camp-specific 3',5'-cyclic phosphodiesterase 4b; PDBTitle: catalytic domain of human phosphodiesterase 4b in complex with2 vardenafil 84 c2w11B_ not modelled 5.9 25 PDB header:hydrolase Chain: B: PDB Molecule:2-haloalkanoic acid dehalogenase; PDBTitle: structure of the l-2-haloacid dehalogenase from sulfolobus2 tokodaii 85 c2ounA_ not modelled 5.9 16 PDB header:hydrolase Chain: A: PDB Molecule:camp and camp-inhibited cgmp 3',5'-cyclic PDBTitle: crystal structure of pde10a2 in complex with amp 86 c3i7aA_ not modelled 5.8 9 PDB header:hydrolase Chain: A: PDB Molecule:putative metal-dependent phosphohydrolase; PDBTitle: crystal structure of putative metal-dependent phosphohydrolase2 (yp_926882.1) from shewanella amazonensis sb2b at 2.06 a resolution 87 c1nw6A_ not modelled 5.7 17 PDB header:transferase Chain: A: PDB Molecule:modification methylase rsri; PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin 88 d1tbfa_ not modelled 5.7 13 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 89 c1xozA_ not modelled 5.7 13 PDB header:hydrolase Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase; PDBTitle: catalytic domain of human phosphodiesterase 5a in complex2 with tadalafil 90 c1es6A_ not modelled 5.6 45 PDB header:viral protein Chain: A: PDB Molecule:matrix protein vp40; PDBTitle: crystal structure of the matrix protein of ebola virus 91 d1oxja1 not modelled 5.6 12 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:SAM (sterile alpha motif) domain 92 d1sv0c_ not modelled 5.5 16 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:Pointed domain 93 d1taza_ not modelled 5.5 31 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 94 d1pv5a_ not modelled 5.4 30 Fold:Hypothetical protein YwqG Superfamily:Hypothetical protein YwqG Family:Hypothetical protein YwqG 95 c2zq5A_ not modelled 5.1 22 PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of sulfotransferase stf1 from2 mycobacterium tuberculosis h37rv (type1 form)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0