Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	D	L	S	H	S	R	E	K	D	K	I	N	P	V	V	F	Y	T	S	A	G	L	I	L	L	F	S	L	T	T	I	L	F	R	D	F	S	A	L	W	I	G	R	T	L	D	W	V	S	K	T	F	G	W	Y	Y	L	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	A	T	L	Y	I	V	F	V	V	C	I	A	C	S	R	F	G	S	V	K	L	G	P	E	Q	S	K	P	E	F	S	L	L	S	W	A	A	M	L	F	A	A	G	I	G	I	D	L	M	F	F	S	V	A	E	P	V	T	Q
Secondary structure
SS confidence
Disorder																										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Y	M	Q	P	P	E	G	A	G	Q	T	I	E	A	A	R	Q	A	M	V	W	T	L	F	H	Y	G	L	T	G	W	S	M	Y	A	L	M	G	M	A	L	G	Y	F	S	Y	R	Y	N	L	P	L	T	I	R	S	A	L	Y	P
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?																																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	F	G	K	R	I	N	G	P	I	G	H	S	V	D	I	A	A	V	I	G	T	I	F	G	I	A	T	T	L	G	I	G	V	V	Q	L	N	Y	G	L	S	V	L	F	D	I	P	D	S	M	A	A	K	A	A	L	I	A	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	V	I	I	A	T	I	S	V	T	S	G	V	D	K	G	I	R	V	L	S	E	L	N	V	A	L	A	L	G	L	I	L	F	V	L	F	M	G	D	T	S	F	L	L	N	A	L	V	L	N	V	G	D	Y	V	N	R	F	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	M	T	L	N	S	F	A	F	D	R	P	V	E	W	M	N	N	W	T	L	F	F	W	A	W	W	V	A	W	S	P	F	V	G	L	F	L	A	R	I	S	R	G	R	T	I	R	Q	F	V	L	G	T	L	I	I	P	F	T
Secondary structure
SS confidence
Disorder												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		F	T	L	L	W	L	S	V	F	G	N	S	A	L	Y	E	I	I	H	G	G	A	A	F	A	E	E	A	M	V	H	P	E	R	G	F	Y	S	L	L	A	Q	Y	P	A	F	T	F	S	A	S	V	A	T	I	T	G	L	L	F
Secondary structure
SS confidence
Disorder																				?		?		?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		Y	V	T	S	A	D	S	G	A	L	V	L	G	N	F	T	S	Q	L	K	D	I	N	S	D	A	P	G	W	L	R	V	F	W	S	V	A	I	G	L	L	T	L	G	M	L	M	T	N	G	I	S	A	L	Q	N	T	T	V	I
Secondary structure
SS confidence
Disorder																		?	?	?	?	?	?	?	?	?	?																						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		M	G	L	P	F	S	F	V	I	F	F	V	M	A	G	L	Y	K	S	L	K	V	E	D	Y	R	R	E	S	A	N	R	D	T	A	P	R	P	L	G	L	Q	D	R	L	S	W	K	K	R	L	S	R	L	M	N	Y	P	G	T
Secondary structure
SS confidence
Disorder																							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?											?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		R	Y	T	K	Q	M	M	E	T	V	C	Y	P	A	M	E	E	V	A	Q	E	L	R	L	R	G	A	Y	V	E	L	K	S	L	P	P	E	E	G	Q	Q	L	G	H	L	D	L	L	V	H	M	G	E	E	Q	N	F	V	Y	Q
Secondary structure
SS confidence
Disorder																									?	?	?		?	?					?		?	?	?	?	?	?	?	?	?								?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		I	W	P	Q	Q	Y	S	V	P	G	F	T	Y	R	A	R	S	G	K	S	T	Y	Y	R	L	E	T	F	L	L	E	G	S	Q	G	N	D	L	M	D	Y	S	K	E	Q	V	I	T	D	I	L	D	Q	Y	E	R	H	L	N	F
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?									?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.
Sequence		I	H	L	H	R	E	A	P	G	H	S	V	M	F	P	D	A
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3hfx chain A Region: 15 - 503 Aligned: 486 Modelled: 486 Confidence: 100.0% Identity: 24% PDB header:transport protein Chain: A: PDB Molecule:l-carnitine/gamma-butyrobetaine antiporter; PDBTitle: crystal structure of carnitine transporter Phyre2 PDB 2w8a chain C Region: 12 - 512 Aligned: 492 Modelled: 475 Confidence: 100.0% Identity: 34% PDB header:membrane protein Chain: C: PDB Molecule:glycine betaine transporter betp; PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate Phyre2 PDB 2xq2 chain A Region: 55 - 494 Aligned: 392 Modelled: 406 Confidence: 98.5% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: structure of the k294a mutant of vsglt Phyre2 PDB 3dh4 chain A Region: 138 - 500 Aligned: 351 Modelled: 351 Confidence: 97.9% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus Phyre2 PDB 2a65 chain A domain 1 Region: 226 - 503 Aligned: 269 Modelled: 278 Confidence: 97.7% Identity: 12% Fold: SNF-like Superfamily: SNF-like Family: SNF-like Phyre2 PDB 2jln chain A Region: 85 - 527 Aligned: 389 Modelled: 389 Confidence: 97.5% Identity: 10% PDB header:membrane protein Chain: A: PDB Molecule:mhp1; PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter Phyre2 PDB 3gia chain A Region: 87 - 509 Aligned: 370 Modelled: 370 Confidence: 96.9% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:uncharacterized protein mj0609; PDBTitle: crystal structure of apct transporter Phyre2 PDB 3lrc chain C Region: 146 - 509 Aligned: 312 Modelled: 312 Confidence: 94.1% Identity: 14% PDB header:transport protein Chain: C: PDB Molecule:arginine/agmatine antiporter; PDBTitle: structure of e. coli adic (p1) Phyre2 PDB 1u7m chain B Region: 643 - 666 Aligned: 24 Modelled: 24 Confidence: 50.3% Identity: 25% PDB header:de novo protein Chain: B: PDB Molecule:four-helix bundle model; PDBTitle: solution structure of a diiron protein model: due ferri(ii)2 turn mutant Phyre2 PDB 1ylx chain A domain 1 Region: 641 - 663 Aligned: 23 Modelled: 23 Confidence: 36.8% Identity: 22% Fold: N domain of copper amine oxidase-like Superfamily: GK1464-like Family: GK1464-like Phyre2 PDB 2hz8 chain A Region: 642 - 671 Aligned: 30 Modelled: 30 Confidence: 36.3% Identity: 27% PDB header:de novo protein Chain: A: PDB Molecule:de novo designed diiron protein; PDBTitle: qm/mm structure refined from nmr-structure of a single2 chain diiron protein Phyre2 PDB 1lt1 chain G Region: 641 - 661 Aligned: 21 Modelled: 21 Confidence: 32.4% Identity: 33% PDB header:de novo protein Chain: G: PDB Molecule:l13g-df1; PDBTitle: sliding helix induced change of coordination geometry in a2 model di-mn(ii) protein Phyre2 PDB 1z2l chain A domain 1 Region: 529 - 593 Aligned: 65 Modelled: 65 Confidence: 25.1% Identity: 9% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Bacterial dinuclear zinc exopeptidases Phyre2 PDB 2cv4 chain A domain 1 Region: 552 - 657 Aligned: 106 Modelled: 106 Confidence: 25.0% Identity: 10% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Glutathione peroxidase-like Phyre2 PDB 3gzt chain F Region: 314 - 323 Aligned: 10 Modelled: 10 Confidence: 22.4% Identity: 30% PDB header:virus Chain: F: PDB Molecule:outer capsid glycoprotein vp7; PDBTitle: vp7 recoated rotavirus dlp Phyre2 PDB 3s0x chain B Region: 5 - 88 Aligned: 67 Modelled: 70 Confidence: 22.4% Identity: 12% PDB header:hydrolase Chain: B: PDB Molecule:peptidase a24b, flak domain protein; PDBTitle: the crystal structure of gxgd membrane protease flak Phyre2 PDB 2kvl chain A Region: 315 - 323 Aligned: 9 Modelled: 9 Confidence: 20.6% Identity: 33% PDB header:viral protein Chain: A: PDB Molecule:major outer capsid protein vp7; PDBTitle: nmr structure of the c-terminal domain of vp7 Phyre2 PDB 2axt chain M domain 1 Region: 264 - 291 Aligned: 26 Modelled: 28 Confidence: 19.8% Identity: 31% Fold: Single transmembrane helix Superfamily: Photosystem II reaction center protein M, PsbM Family: PsbM-like Phyre2 PDB 1j5y chain A domain 2 Region: 535 - 567 Aligned: 33 Modelled: 33 Confidence: 19.0% Identity: 12% Fold: HPr-like Superfamily: Putative transcriptional regulator TM1602, C-terminal domain Family: Putative transcriptional regulator TM1602, C-terminal domain Phyre2 PDB 2guk chain A domain 1 Region: 649 - 659 Aligned: 11 Modelled: 11 Confidence: 17.6% Identity: 45% Fold: PG1857-like Superfamily: PG1857-like Family: PG1857-like Phyre2 1 c3hfxA_ 2 c2w8aC_ 3 c2xq2A_ 4 c3dh4A_ 5 d2a65a1 6 c2jlnA_ 7 c3giaA_ 8 c3lrcC_ 9 c1u7mB_ 10 d1ylxa1 11 c2hz8A_ 12 c1lt1G_ 13 d1z2la1 14 d2cv4a1 15 c3gztF_ 16 c3s0xB_ 17 c2kvlA_ 18 d2axtm1 19 d1j5ya2 20 d2guka1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99