Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	N	K	P	F	I	Y	Q	A	P	F	P	M	G	K	D	N	T	E	Y	Y	L	L	T	S	D	Y	V	S	V	A	D	F	D	G	E	T	I	L	K	V	E	P	E	A	L	T	L	L	A	Q	Q	A	F	H	D	A	S	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	L	R	P	A	H	Q	K	Q	V	A	A	I	L	H	D	P	E	A	S	E	N	D	K	Y	V	A	L	Q	F	L	R	N	S	E	I	A	A	K	G	V	L	P	T	C	Q	D	T	G	T	A	I	I	V	G	K	K	G	Q	R
Secondary structure
SS confidence
Disorder																	?			?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	W	T	G	G	G	D	E	E	T	L	S	K	G	V	Y	N	T	Y	I	E	D	N	L	R	Y	S	Q	N	A	A	L	D	M	Y	K	E	V	N	T	G	T	N	L	P	A	Q	I	D	L	Y	A	V	D	G	D	E	Y	K	F
Secondary structure
SS confidence
Disorder																														?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	C	V	A	K	G	G	G	S	A	N	K	T	Y	L	Y	Q	E	T	K	A	L	L	T	P	G	K	L	K	N	F	L	V	E	K	M	R	T	L	G	T	A	A	C	P	P	Y	H	I	A	F	V	I	G	G	T	S	A	E	T
Secondary structure
SS confidence
Disorder																		?			?		?	?																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		N	L	K	T	V	K	L	A	S	A	H	Y	Y	D	E	L	P	T	E	G	N	E	H	G	Q	A	F	R	D	V	Q	L	E	Q	E	L	L	E	E	A	Q	K	L	G	L	G	A	Q	F	G	G	K	Y	F	A	H	D	I	R	V
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?	?																			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		I	R	L	P	R	H	G	A	S	C	P	V	G	M	G	V	S	C	S	A	D	R	N	I	K	A	K	I	N	R	E	G	I	W	I	E	K	L	E	H	N	P	G	Q	Y	I	P	Q	E	L	R	Q	A	G	E	G	E	A	V	K
Secondary structure
SS confidence
Disorder																																																						?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		V	D	L	N	R	P	M	K	E	I	L	A	Q	L	S	Q	Y	P	V	S	T	R	L	S	L	T	G	T	I	I	V	G	R	D	I	A	H	A	K	L	K	E	L	I	D	A	G	K	E	L	P	Q	Y	I	K	D	H	P	I	Y
Secondary structure
SS confidence
Disorder										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		Y	A	G	P	A	K	T	P	A	G	Y	P	S	G	S	L	G	P	T	T	A	G	R	M	D	S	Y	V	D	L	L	Q	S	H	G	G	S	M	I	M	L	A	K	G	N	R	S	Q	Q	V	T	D	A	C	H	K	H	G	G	F
Secondary structure
SS confidence
Disorder									?	?																										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		Y	L	G	S	I	G	G	P	A	A	V	L	A	Q	Q	S	I	K	H	L	E	C	V	A	Y	P	E	L	G	M	E	A	I	W	K	I	E	V	E	D	F	P	A	F	I	L	V	D	D	K	G	N	D	F	F	Q	Q	I	V	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.
Sequence		K	Q	C	A	N	C	T	K
Secondary structure
SS confidence
Disorder								?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2isb chain A domain 1 Region: 361 - 536 Aligned: 172 Modelled: 176 Confidence: 100.0% Identity: 31% Fold: The "swivelling" beta/beta/alpha domain Superfamily: FumA C-terminal domain-like Family: FumA C-terminal domain-like Phyre2 PDB 1ed7 chain A Region: 377 - 393 Aligned: 17 Modelled: 17 Confidence: 58.8% Identity: 12% Fold: WW domain-like Superfamily: Carbohydrate binding domain Family: Carbohydrate binding domain Phyre2 PDB 1k98 chain A Region: 339 - 419 Aligned: 80 Modelled: 81 Confidence: 53.2% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:methionine synthase; PDBTitle: adomet complex of meth c-terminal fragment Phyre2 PDB 3fpn chain A Region: 364 - 419 Aligned: 56 Modelled: 56 Confidence: 51.0% Identity: 21% PDB header:dna binding protein Chain: A: PDB Molecule:geobacillus stearothermophilus uvra interaction PDBTitle: crystal structure of uvra-uvrb interaction domains Phyre2 PDB 2xmo chain B Region: 367 - 406 Aligned: 39 Modelled: 40 Confidence: 38.2% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 Phyre2 PDB 1ei5 chain A domain 2 Region: 312 - 327 Aligned: 16 Modelled: 16 Confidence: 37.1% Identity: 25% Fold: Streptavidin-like Superfamily: D-aminopeptidase, middle and C-terminal domains Family: D-aminopeptidase, middle and C-terminal domains Phyre2 PDB 3l07 chain B Region: 193 - 283 Aligned: 86 Modelled: 91 Confidence: 36.5% Identity: 17% PDB header:oxidoreductase,hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate2 cyclohydrolase, putative bifunctional protein fold from francisella3 tularensis. Phyre2 PDB 3bul chain A domain 2 Region: 359 - 419 Aligned: 60 Modelled: 61 Confidence: 36.4% Identity: 25% Fold: Flavodoxin-like Superfamily: Cobalamin (vitamin B12)-binding domain Family: Cobalamin (vitamin B12)-binding domain Phyre2 PDB 3p2o chain A Region: 206 - 283 Aligned: 73 Modelled: 78 Confidence: 35.8% Identity: 18% PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni Phyre2 PDB 12as chain A Region: 465 - 507 Aligned: 40 Modelled: 43 Confidence: 34.3% Identity: 18% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 3p2o chain B Region: 206 - 283 Aligned: 73 Modelled: 78 Confidence: 32.4% Identity: 18% PDB header:oxidoreductase, hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni Phyre2 PDB 2zoe chain A Region: 17 - 38 Aligned: 22 Modelled: 22 Confidence: 31.2% Identity: 23% PDB header:toxin Chain: A: PDB Molecule:hemagglutinin components ha3; PDBTitle: ha3 subcomponent of clostridium botulinum type c progenitor2 toxin, complex with n-acetylneuramic acid Phyre2 PDB 2d49 chain A Region: 377 - 393 Aligned: 17 Modelled: 17 Confidence: 28.5% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:chitinase c; PDBTitle: solution structure of the chitin-binding domain of2 streptomyces griseus chitinase c Phyre2 PDB 2c2x chain B Region: 206 - 283 Aligned: 73 Modelled: 78 Confidence: 28.4% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase- PDBTitle: three dimensional structure of bifunctional2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase3 from mycobacterium tuberculosis Phyre2 PDB 2e0i chain D Region: 329 - 378 Aligned: 50 Modelled: 50 Confidence: 28.3% Identity: 12% PDB header:lyase Chain: D: PDB Molecule:432aa long hypothetical deoxyribodipyrimidine photolyase; PDBTitle: crystal structure of archaeal photolyase from sulfolobus tokodaii with2 two fad molecules: implication of a novel light-harvesting cofactor Phyre2 PDB 1a4i chain A domain 2 Region: 206 - 284 Aligned: 74 Modelled: 79 Confidence: 26.5% Identity: 16% Fold: Aminoacid dehydrogenase-like, N-terminal domain Superfamily: Aminoacid dehydrogenase-like, N-terminal domain Family: Tetrahydrofolate dehydrogenase/cyclohydrolase Phyre2 PDB 1aiw chain A Region: 380 - 393 Aligned: 14 Modelled: 14 Confidence: 25.7% Identity: 7% Fold: WW domain-like Superfamily: Carbohydrate binding domain Family: Carbohydrate binding domain Phyre2 PDB 2pie chain A domain 1 Region: 320 - 385 Aligned: 48 Modelled: 66 Confidence: 25.4% Identity: 21% Fold: SMAD/FHA domain Superfamily: SMAD/FHA domain Family: FHA domain Phyre2 PDB 1vkz chain A domain 2 Region: 457 - 489 Aligned: 33 Modelled: 33 Confidence: 24.2% Identity: 21% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: BC N-terminal domain-like Phyre2 PDB 1yqe chain A domain 1 Region: 107 - 143 Aligned: 37 Modelled: 37 Confidence: 24.1% Identity: 8% Fold: Phosphorylase/hydrolase-like Superfamily: AF0625-like Family: AF0625-like Phyre2 1 d2isba1 2 d1ed7a_ 3 c1k98A_ 4 c3fpnA_ 5 c2xmoB_ 6 d1ei5a2 7 c3l07B_ 8 d3bula2 9 c3p2oA_ 10 d12asa_ 11 c3p2oB_ 12 c2zoeA_ 13 c2d49A_ 14 c2c2xB_ 15 c2e0iD_ 16 d1a4ia2 17 d1aiwa_ 18 d2piea1 19 d1vkza2 20 d1yqea1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2isba1 100.0 31 Fold:The "swivelling" beta/beta/alpha domain Superfamily:FumA C-terminal domain-like Family:FumA C-terminal domain-like 2 d1ed7a_ 58.8 12 Fold:WW domain-like Superfamily:Carbohydrate binding domain Family:Carbohydrate binding domain 3 c1k98A_ 53.2 21 PDB header:transferase Chain: A: PDB Molecule:methionine synthase; PDBTitle: adomet complex of meth c-terminal fragment 4 c3fpnA_ 51.0 21 PDB header:dna binding protein Chain: A: PDB Molecule:geobacillus stearothermophilus uvra interaction PDBTitle: crystal structure of uvra-uvrb interaction domains 5 c2xmoB_ 38.2 18 PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 6 d1ei5a2 37.1 25 Fold:Streptavidin-like Superfamily:D-aminopeptidase, middle and C-terminal domains Family:D-aminopeptidase, middle and C-terminal domains 7 c3l07B_ 36.5 17 PDB header:oxidoreductase,hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate2 cyclohydrolase, putative bifunctional protein fold from francisella3 tularensis. 8 d3bula2 36.4 25 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 9 c3p2oA_ 35.8 18 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 10 d12asa_ 34.3 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 11 c3p2oB_ 32.4 18 PDB header:oxidoreductase, hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 12 c2zoeA_ 31.2 23 PDB header:toxin Chain: A: PDB Molecule:hemagglutinin components ha3; PDBTitle: ha3 subcomponent of clostridium botulinum type c progenitor2 toxin, complex with n-acetylneuramic acid 13 c2d49A_ 28.5 18 PDB header:hydrolase Chain: A: PDB Molecule:chitinase c; PDBTitle: solution structure of the chitin-binding domain of2 streptomyces griseus chitinase c 14 c2c2xB_ 28.4 14 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase- PDBTitle: three dimensional structure of bifunctional2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase3 from mycobacterium tuberculosis 15 c2e0iD_ 28.3 12 PDB header:lyase Chain: D: PDB Molecule:432aa long hypothetical deoxyribodipyrimidine photolyase; PDBTitle: crystal structure of archaeal photolyase from sulfolobus tokodaii with2 two fad molecules: implication of a novel light-harvesting cofactor 16 d1a4ia2 26.5 16 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Tetrahydrofolate dehydrogenase/cyclohydrolase 17 d1aiwa_ 25.7 7 Fold:WW domain-like Superfamily:Carbohydrate binding domain Family:Carbohydrate binding domain 18 d2piea1 25.4 21 Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain 19 d1vkza2 24.2 21 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 20 d1yqea1 24.1 8 Fold:Phosphorylase/hydrolase-like Superfamily:AF0625-like Family:AF0625-like 21 c2gfqC_ not modelled 23.6 9 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:upf0204 protein ph0006; PDBTitle: structure of protein of unknown function ph0006 from pyrococcus2 horikoshii 22 c3lzkC_ not modelled 23.4 18 PDB header:hydrolase Chain: C: PDB Molecule:fumarylacetoacetate hydrolase family protein; PDBTitle: the crystal structure of a probably aromatic amino acid2 degradation protein from sinorhizobium meliloti 1021 23 c3cr8C_ not modelled 22.7 27 PDB header:transferase Chain: C: PDB Molecule:sulfate adenylyltranferase, adenylylsulfate PDBTitle: hexameric aps kinase from thiobacillus denitrificans 24 d1b8aa1 not modelled 22.6 6 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Anticodon-binding domain 25 d1goia1 not modelled 21.8 18 Fold:WW domain-like Superfamily:Carbohydrate binding domain Family:Carbohydrate binding domain 26 d1o6aa_ not modelled 21.5 13 Fold:Surface presentation of antigens (SPOA) Superfamily:Surface presentation of antigens (SPOA) Family:Surface presentation of antigens (SPOA) 27 d1v58a1 not modelled 21.3 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:DsbC/DsbG C-terminal domain-like 28 d2gqba1 not modelled 21.2 35 Fold:RPA2825-like Superfamily:RPA2825-like Family:RPA2825-like 29 c3orsD_ not modelled 21.1 14 PDB header:isomerase,biosynthetic protein Chain: D: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase; PDBTitle: crystal structure of n5-carboxyaminoimidazole ribonucleotide mutase2 from staphylococcus aureus 30 d2gfqa1 not modelled 20.5 9 Fold:Phosphorylase/hydrolase-like Superfamily:AF0625-like Family:AF0625-like 31 c2crvA_ not modelled 19.6 18 PDB header:translation Chain: A: PDB Molecule:translation initiation factor if-2; PDBTitle: solution structure of c-terminal domain of mitochondrial2 translational initiationfactor 2 32 d1vjea_ not modelled 19.3 25 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:Autoinducer-2 production protein LuxS 33 d1ooya2 not modelled 19.2 19 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:CoA transferase alpha subunit-like 34 d1muja2 not modelled 18.4 35 Fold:MHC antigen-recognition domain Superfamily:MHC antigen-recognition domain Family:MHC antigen-recognition domain 35 d1ni9a_ not modelled 18.1 23 Fold:Carbohydrate phosphatase Superfamily:Carbohydrate phosphatase Family:GlpX-like bacterial fructose-1,6-bisphosphatase 36 c3trhI_ not modelled 17.8 10 PDB header:lyase Chain: I: PDB Molecule:phosphoribosylaminoimidazole carboxylase PDBTitle: structure of a phosphoribosylaminoimidazole carboxylase catalytic2 subunit (pure) from coxiella burnetii 37 c2j7pA_ not modelled 17.4 17 PDB header:signal recognition Chain: A: PDB Molecule:signal recognition particle protein; PDBTitle: gmppnp-stabilized ng domain complex of the srp gtpases ffh2 and ftsy 38 c3uotB_ not modelled 17.3 6 PDB header:cell cycle Chain: B: PDB Molecule:mediator of dna damage checkpoint protein 1; PDBTitle: crystal structure of mdc1 fha domain in complex with a phosphorylated2 peptide from the mdc1 n-terminus 39 d2piaa1 not modelled 17.1 0 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 40 c2qv6D_ not modelled 17.0 9 PDB header:hydrolase Chain: D: PDB Molecule:gtp cyclohydrolase iii; PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions 41 d1edza2 not modelled 17.0 10 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Tetrahydrofolate dehydrogenase/cyclohydrolase 42 d2cp6a1 not modelled 16.5 15 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 43 d2oz4a1 not modelled 16.2 31 Fold:Immunoglobulin-like beta-sandwich Superfamily:Immunoglobulin Family:C2 set domains 44 d1j98a_ not modelled 16.1 45 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:Autoinducer-2 production protein LuxS 45 d2vzsa5 not modelled 16.1 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 46 d1g3ga_ not modelled 16.0 17 Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain 47 d1fnda1 not modelled 15.8 29 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 48 c3ff4A_ not modelled 15.6 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein chu_1412 49 d2eyqa1 not modelled 15.5 6 Fold:SH3-like barrel Superfamily:CarD-like Family:CarD-like 50 c3c00B_ not modelled 15.1 11 PDB header:membrane protein, protein transport Chain: B: PDB Molecule:escu; PDBTitle: crystal structural of the mutated g247t escu/spas c-terminal domain 51 c3eeqB_ not modelled 15.0 31 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative cobalamin biosynthesis protein g PDBTitle: crystal structure of a putative cobalamin biosynthesis2 protein g homolog from sulfolobus solfataricus 52 d1jr2a_ not modelled 14.8 21 Fold:HemD-like Superfamily:HemD-like Family:HemD-like 53 c1jr2A_ not modelled 14.8 21 PDB header:lyase Chain: A: PDB Molecule:uroporphyrinogen-iii synthase; PDBTitle: structure of uroporphyrinogen iii synthase 54 d1n0ua3 not modelled 14.7 10 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Translational machinery components 55 c2l9dA_ not modelled 14.7 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of the protein yp_546394.1, the first structural2 representative of the pfam family pf12112 56 d1uhta_ not modelled 14.4 13 Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain 57 d1sf8a_ not modelled 14.0 23 Fold:HSP90 C-terminal domain Superfamily:HSP90 C-terminal domain Family:HSP90 C-terminal domain 58 c2iheA_ not modelled 13.9 15 PDB header:dna binding protein Chain: A: PDB Molecule:single-stranded dna-binding protein; PDBTitle: crystal structure of wild-type single-stranded dna binding protein2 from thermus aquaticus 59 c3kw0D_ not modelled 13.4 12 PDB header:hydrolase Chain: D: PDB Molecule:cysteine peptidase; PDBTitle: crystal structure of cysteine peptidase (np_982244.1) from bacillus2 cereus atcc 10987 at 2.50 a resolution 60 d1a5ra_ not modelled 13.4 11 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:Ubiquitin-related 61 c3qq5A_ not modelled 13.3 20 PDB header:oxidoreductase Chain: A: PDB Molecule:small gtp-binding protein; PDBTitle: crystal structure of the [fefe]-hydrogenase maturation protein hydf 62 d1owla1 not modelled 13.0 14 Fold:Cryptochrome/photolyase FAD-binding domain Superfamily:Cryptochrome/photolyase FAD-binding domain Family:Cryptochrome/photolyase FAD-binding domain 63 c3fmxX_ not modelled 13.0 17 PDB header:oxidoreductase Chain: X: PDB Molecule:tartrate dehydrogenase/decarboxylase; PDBTitle: crystal structure of tartrate dehydrogenase from pseudomonas2 putida complexed with nadh 64 c1tezB_ not modelled 12.9 14 PDB header:lyase/dna Chain: B: PDB Molecule:deoxyribodipyrimidine photolyase; PDBTitle: complex between dna and the dna photolyase from anacystis nidulans 65 d1es0a2 not modelled 12.8 35 Fold:MHC antigen-recognition domain Superfamily:MHC antigen-recognition domain Family:MHC antigen-recognition domain 66 c3mxnB_ not modelled 12.6 24 PDB header:replication Chain: B: PDB Molecule:recq-mediated genome instability protein 2; PDBTitle: crystal structure of the rmi core complex 67 c3cyyA_ not modelled 12.5 22 PDB header:peptide binding protein Chain: A: PDB Molecule:tight junction protein zo-1; PDBTitle: the crystal structure of zo-1 pdz2 in complex with the cx43 peptide 68 c2jlhA_ not modelled 12.5 13 PDB header:protein transport Chain: A: PDB Molecule:yop proteins translocation protein u; PDBTitle: crystal structure of the cytoplasmic domain of yersinia2 pestis yscu n263a mutant 69 c3en2A_ not modelled 12.4 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:probable primosomal replication protein n; PDBTitle: three-dimensional structure of the protein prib from2 ralstonia solanacearum at the resolution 2.3a. northeast3 structural genomics consortium target rsr213c. 70 d2gc6a1 not modelled 12.4 18 Fold:MurD-like peptide ligases, peptide-binding domain Superfamily:MurD-like peptide ligases, peptide-binding domain Family:Folylpolyglutamate synthetase, C-terminal domain 71 d1u3da1 not modelled 12.3 20 Fold:Cryptochrome/photolyase FAD-binding domain Superfamily:Cryptochrome/photolyase FAD-binding domain Family:Cryptochrome/photolyase FAD-binding domain 72 c3chvA_ not modelled 12.3 18 PDB header:metal binding protein Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution 73 c1a4iB_ not modelled 12.0 16 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase / PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase 74 c3ibgF_ not modelled 12.0 17 PDB header:hydrolase Chain: F: PDB Molecule:atpase, subunit of the get complex; PDBTitle: crystal structure of aspergillus fumigatus get3 with bound2 adp 75 c2oqjF_ not modelled 11.9 71 PDB header:immune system Chain: F: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 76 d2coza1 not modelled 11.8 16 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 77 c3o59X_ not modelled 11.6 46 PDB header:transferase Chain: X: PDB Molecule:dna polymerase ii large subunit; PDBTitle: dna polymerase d large subunit dp2(1-300) from pyrococcus horikoshii 78 c3t7yB_ not modelled 11.6 11 PDB header:protein transport Chain: B: PDB Molecule:yop proteins translocation protein u; PDBTitle: structure of an autocleavage-inactive mutant of the cytoplasmic domain2 of ct091, the yscu homologue of chlamydia trachomatis 79 d2f2ab1 not modelled 11.5 19 Fold:GatB/YqeY motif Superfamily:GatB/YqeY motif Family:GatB/GatE C-terminal domain-like 80 d1c0aa1 not modelled 11.5 21 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Anticodon-binding domain 81 d2cnda1 not modelled 11.4 25 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 82 d4ubpb_ not modelled 11.1 17 Fold:beta-clip Superfamily:Urease, beta-subunit Family:Urease, beta-subunit 83 d1o9ya_ not modelled 11.1 20 Fold:Surface presentation of antigens (SPOA) Superfamily:Surface presentation of antigens (SPOA) Family:Surface presentation of antigens (SPOA) 84 d1e9ya1 not modelled 11.0 12 Fold:beta-clip Superfamily:Urease, beta-subunit Family:Urease, beta-subunit 85 d2ew0a1 not modelled 11.0 22 Fold:VC0467-like Superfamily:VC0467-like Family:VC0467-like 86 c3d8tB_ not modelled 10.9 20 PDB header:lyase Chain: B: PDB Molecule:uroporphyrinogen-iii synthase; PDBTitle: thermus thermophilus uroporphyrinogen iii synthase 87 c2oqjL_ not modelled 10.8 71 PDB header:immune system Chain: L: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 88 c2oqjI_ not modelled 10.8 71 PDB header:immune system Chain: I: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 89 c2oqjC_ not modelled 10.8 71 PDB header:immune system Chain: C: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 90 d1e32a1 not modelled 10.8 10 Fold:Double psi beta-barrel Superfamily:ADC-like Family:Cdc48 N-terminal domain-like 91 d1pcfa_ not modelled 10.6 47 Fold:ssDNA-binding transcriptional regulator domain Superfamily:ssDNA-binding transcriptional regulator domain Family:Transcriptional coactivator PC4 C-terminal domain 92 c3rfuC_ not modelled 10.4 15 PDB header:hydrolase, membrane protein Chain: C: PDB Molecule:copper efflux atpase; PDBTitle: crystal structure of a copper-transporting pib-type atpase 93 c1zgxA_ not modelled 10.3 18 PDB header:hydrolase Chain: A: PDB Molecule:guanyl-specific ribonuclease sa; PDBTitle: crystal structure of ribonuclease mutant 94 c2ihfA_ not modelled 10.3 15 PDB header:dna binding protein Chain: A: PDB Molecule:single-stranded dna-binding protein; PDBTitle: crystal structure of deletion mutant delta 228-252 r190a of the2 single-stranded dna binding protein from thermus aquaticus 95 d1sm4a1 not modelled 10.2 21 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 96 d1qx4a1 not modelled 10.2 14 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 97 d1xnea_ not modelled 10.2 15 Fold:PUA domain-like Superfamily:PUA domain-like Family:ProFAR isomerase associated domain 98 d1krha1 not modelled 10.1 29 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 99 c3op0B_ not modelled 10.1 58 PDB header:signaling protein/signaling protein regu Chain: B: PDB Molecule:signal transduction protein cbl-c; PDBTitle: crystal structure of cbl-c (cbl-3) tkb domain in complex with egfr2 py1069 peptide

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0