Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP24177
DateWed Jan 25 15:20:44 GMT 2012
Unique Job ID8137cd87d7d9248b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1oy8A_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
Confidence and coverage
Confidence:100.0% Coverage: 97%
1005 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENT
Secondary structure 
SS confidence 
Disorder  ??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  VTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQ
Secondary structure 
SS confidence 
Disorder 
???
??
????
????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  AVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQDPLSRVNGVGDIDAYGS
Secondary structure 
SS confidence 
Disorder 
?
?
??
?
?
??
?????
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  QYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL
Secondary structure 
SS confidence 
Disorder 
?
???????????????????
?
??
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  QTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEM
Secondary structure 
SS confidence 
Disorder 
??
???
???
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  ATAELVLNRLDELAQYFPHGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQ
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  NFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLAIGLLVDDAIVVVENVERIM
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  SEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVL
Secondary structure 
SS confidence 
Disorder 
???
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  SVLVAMILTPALCATLLKPLKKGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSLRW
Secondary structure 
SS confidence 
Disorder 
????????????
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  IVIYVLLLGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTH
Secondary structure 
SS confidence 
Disorder 
????
??
?
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  EKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSKTGTSFAIIERATKAFNQIKEA
Secondary structure 
SS confidence 
Disorder 
????????????
??????
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  RVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLD
Secondary structure 
SS confidence 
Disorder 
???????????????
?
?
?
?
????
Disorder confidence 
 
   .........730.........740.........750.........760.........770.........780
Sequence  DSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRML
Secondary structure 
SS confidence 
Disorder 
?
?
???
Disorder confidence 
 
   .........790.........800.........810.........820.........830.........840
Sequence  PDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMD
Secondary structure 
SS confidence 
Disorder  ?
?
?
??
?
?????
???
??????
Disorder confidence 
 
   .........850.........860.........870.........880.........890.........900
Sequence  IMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVM
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........910.........920.........930.........940.........950.........960
Sequence  LVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA
Secondary structure 
SS confidence 
Disorder 
?
?
?
Disorder confidence 
 
   .........970.........980.........990.........1000.........1010.........1020
Sequence  TLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVP
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........1030.......
Sequence  LFFVLVRRRFPLKPRPE
Secondary structure 
SS confidence 
Disorder 
????????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1oy8 chain A

3D model

Region: 7 - 1033
Aligned: 1005
Modelled: 1027
Confidence: 100.0%
Identity: 66%
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump

Phyre2

PDB 3k07 chain A

3D model

Region: 1 - 1027
Aligned: 999
Modelled: 1007
Confidence: 100.0%
Identity: 21%
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa

Phyre2

PDB 3aqp chain B

3D model

Region: 85 - 1029
Aligned: 675
Modelled: 715
Confidence: 100.0%
Identity: 16%
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus

Phyre2

PDB 1iwg chain A domain 8

3D model

Region: 835 - 1033
Aligned: 199
Modelled: 199
Confidence: 100.0%
Identity: 68%
Fold: Multidrug efflux transporter AcrB transmembrane domain
Superfamily: Multidrug efflux transporter AcrB transmembrane domain
Family: Multidrug efflux transporter AcrB transmembrane domain

Phyre2

PDB 1iwg chain A domain 7

3D model

Region: 306 - 498
Aligned: 193
Modelled: 193
Confidence: 100.0%
Identity: 79%
Fold: Multidrug efflux transporter AcrB transmembrane domain
Superfamily: Multidrug efflux transporter AcrB transmembrane domain
Family: Multidrug efflux transporter AcrB transmembrane domain

Phyre2

PDB 1iwg chain A domain 1

3D model

Region: 38 - 134
Aligned: 97
Modelled: 97
Confidence: 99.8%
Identity: 61%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 1iwg chain A domain 5

3D model

Region: 182 - 273
Aligned: 92
Modelled: 92
Confidence: 99.5%
Identity: 59%
Fold: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains

Phyre2

PDB 1iwg chain A domain 2

3D model

Region: 231 - 330
Aligned: 99
Modelled: 100
Confidence: 99.5%
Identity: 35%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 1iwg chain A domain 6

3D model

Region: 723 - 810
Aligned: 88
Modelled: 88
Confidence: 99.1%
Identity: 75%
Fold: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains

Phyre2

PDB 1iwg chain A domain 3

3D model

Region: 567 - 672
Aligned: 106
Modelled: 106
Confidence: 98.9%
Identity: 49%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 1iwg chain A domain 4

3D model

Region: 673 - 857
Aligned: 97
Modelled: 97
Confidence: 98.3%
Identity: 64%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 2rop chain A

3D model

Region: 62 - 209
Aligned: 119
Modelled: 130
Confidence: 95.9%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of domains 3 and 4 of human atp7b

Phyre2

PDB 2ew9 chain A

3D model

Region: 62 - 209
Aligned: 122
Modelled: 148
Confidence: 95.7%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of apowln5-6

Phyre2

PDB 2rml chain A

3D model

Region: 62 - 209
Aligned: 114
Modelled: 127
Confidence: 93.7%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting p-type atpase copa;
PDBTitle: solution structure of the n-terminal soluble domains of2 bacillus subtilis copa

Phyre2

PDB 1s6u chain A

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 90.7%
Identity: 22%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 2aw0 chain A

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 90.4%
Identity: 24%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 1cpz chain A

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 90.4%
Identity: 22%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 2qif chain A domain 1

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 89.8%
Identity: 22%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 3dxs chain X

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 89.2%
Identity: 26%
PDB header:hydrolase
Chain: X: PDB Molecule:copper-transporting atpase ran1;
PDBTitle: crystal structure of a copper binding domain from hma7, a p-2 type atpase

Phyre2

PDB 1kvj chain A

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 89.0%
Identity: 30%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2
1
c1oy8A_
2
c3k07A_
3
c3aqpB_
4
d1iwga8
5
d1iwga7
6
d1iwga1
7
d1iwga5
8
d1iwga2
9
d1iwga6
10
d1iwga3
11
d1iwga4
12
c2ropA_
13
c2ew9A_
14
c2rmlA_
15
d1s6ua_
16
d2aw0a_
17
d1cpza_
18
d2qifa1
19
c3dxsX_
20
d1kvja_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1oy8A_
100.0 66 PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
2c3k07A_
100.0 21 PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
3c3aqpB_
100.0 16 PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
4d1iwga8
100.0 68 Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
5d1iwga7
100.0 79 Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
6d1iwga1
99.8 61 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
7d1iwga5
99.5 59 Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
8d1iwga2
99.5 35 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
9d1iwga6
99.1 75 Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
10d1iwga3
98.9 49 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
11d1iwga4
98.3 64 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
12c2ropA_
95.9 18 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of domains 3 and 4 of human atp7b
13c2ew9A_
95.7 15 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of apowln5-6
14c2rmlA_
93.7 13 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting p-type atpase copa;
PDBTitle: solution structure of the n-terminal soluble domains of2 bacillus subtilis copa
15d1s6ua_
90.7 22 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
16d2aw0a_
90.4 24 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
17d1cpza_
90.4 22 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
18d2qifa1
89.8 22 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
19c3dxsX_
89.2 26 PDB header:hydrolase
Chain: X: PDB Molecule:copper-transporting atpase ran1;
PDBTitle: crystal structure of a copper binding domain from hma7, a p-2 type atpase
20d1kvja_
89.0 30 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
21c2l3mA_
not modelled 89.0 24 PDB header:metal binding protein
Chain: A: PDB Molecule:copper-ion-binding protein;
PDBTitle: solution structure of the putative copper-ion-binding protein from2 bacillus anthracis str. ames
22d1q8la_
not modelled 88.4 22 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
23c1yjrA_
not modelled 87.7 22 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the apo form of the sixth soluble2 domain a69p mutant of menkes protein
24c2ga7A_
not modelled 87.3 28 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the copper(i) form of the third metal-2 binding domain of atp7a protein (menkes disease protein)
25d1p6ta2
not modelled 87.3 17 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
26c2ldiA_
not modelled 87.2 24 PDB header:hydrolase
Chain: A: PDB Molecule:zinc-transporting atpase;
PDBTitle: nmr solution structure of ziaan sub mutant
27c2kkhA_
not modelled 86.0 15 PDB header:metal transport
Chain: A: PDB Molecule:putative heavy metal transporter;
PDBTitle: structure of the zinc binding domain of the atpase hma4
28c1yg0A_
not modelled 85.5 22 PDB header:metal transport
Chain: A: PDB Molecule:cop associated protein;
PDBTitle: solution structure of apo-copp from helicobacter pylori
29c2kt2A_
not modelled 85.2 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:mercuric reductase;
PDBTitle: structure of nmera, the n-terminal hma domain of tn501 mercuric2 reductase
30d1p6ta1
not modelled 85.2 24 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
31d1osda_
not modelled 84.7 22 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
32c2yvxD_
not modelled 84.2 15 PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
33d1afia_
not modelled 84.1 20 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
34c2ofhX_
not modelled 81.7 20 PDB header:hydrolase, membrane protein
Chain: X: PDB Molecule:zinc-transporting atpase;
PDBTitle: solution structure of the n-terminal domain of the zinc(ii) atpase2 ziaa in its apo form
35c1y3kA_
not modelled 80.4 20 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the apo form of the fifth domain of2 menkes protein
36d2ggpb1
not modelled 77.3 24 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
37d1mwza_
not modelled 75.7 14 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
38d1qupa2
not modelled 75.6 14 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
39c2gcfA_
not modelled 74.8 24 PDB header:hydrolase
Chain: A: PDB Molecule:cation-transporting atpase pacs;
PDBTitle: solution structure of the n-terminal domain of the coppper(i) atpase2 pacs in its apo form
40c2k2pA_
not modelled 74.0 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein atu1203;
PDBTitle: solution nmr structure of protein atu1203 from agrobacterium2 tumefaciens. northeast structural genomics consortium (nesg) target3 att10, ontario center for structural proteomics target atc1183
41c1jk9D_
not modelled 73.8 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:copper chaperone for superoxide dismutase;
PDBTitle: heterodimer between h48f-ysod1 and yccs
42c3j09A_
not modelled 73.5 17 PDB header:hydrolase, metal transport
Chain: A: PDB Molecule:copper-exporting p-type atpase a;
PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa
43d1sb6a_
not modelled 70.9 12 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
44c2aj1A_
not modelled 70.4 9 PDB header:hydrolase
Chain: A: PDB Molecule:probable cadmium-transporting atpase;
PDBTitle: solution structure of apocada
45c2rogA_
not modelled 69.8 16 PDB header:metal binding protein
Chain: A: PDB Molecule:heavy metal binding protein;
PDBTitle: solution structure of thermus thermophilus hb8 ttha17182 protein in living e. coli cells
46c1qupA_
not modelled 64.6 14 PDB header:chaperone
Chain: A: PDB Molecule:superoxide dismutase 1 copper chaperone;
PDBTitle: crystal structure of the copper chaperone for superoxide2 dismutase
47c2crlA_
not modelled 64.3 16 PDB header:chaperone
Chain: A: PDB Molecule:copper chaperone for superoxide dismutase;
PDBTitle: the apo form of hma domain of copper chaperone for2 superoxide dismutase
48d1cc8a_
not modelled 57.1 12 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
49c1yj7A_
not modelled 53.8 19 PDB header:protein transport
Chain: A: PDB Molecule:escj;
PDBTitle: crystal structure of enteropathogenic e.coli (epec) type iii secretion2 system protein escj
50d2nwwa1
not modelled 53.0 7 Fold:Proton glutamate symport protein
Superfamily:Proton glutamate symport protein
Family:Proton glutamate symport protein
51c2kyzA_
not modelled 47.9 15 PDB header:metal binding protein
Chain: A: PDB Molecule:heavy metal binding protein;
PDBTitle: nmr structure of heavy metal binding protein tm0320 from thermotoga2 maritima
52d1pw4a_
not modelled 43.9 7 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:Glycerol-3-phosphate transporter
53d2yvxa3
not modelled 42.5 16 Fold:MgtE membrane domain-like
Superfamily:MgtE membrane domain-like
Family:MgtE membrane domain-like
54d2cu6a1
not modelled 42.3 18 Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:PaaD-like
55d1uwda_
not modelled 39.7 18 Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:PaaD-like
56c2yy3B_
not modelled 38.5 6 PDB header:translation
Chain: B: PDB Molecule:elongation factor 1-beta;
PDBTitle: crystal structure of translation elongation factor ef-1 beta from2 pyrococcus horikoshii
57d2vv5a2
not modelled 34.0 18 Fold:Ferredoxin-like
Superfamily:Mechanosensitive channel protein MscS (YggB), C-terminal domain
Family:Mechanosensitive channel protein MscS (YggB), C-terminal domain
58c1ciiA_
not modelled 31.3 15 PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
59c3fryB_
not modelled 24.3 10 PDB header:hydrolase
Chain: B: PDB Molecule:probable copper-exporting p-type atpase a;
PDBTitle: crystal structure of the copa c-terminal metal binding domain
60c3lnoA_
not modelled 23.7 19 PDB header:unknown function
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of domain of unknown function duf59 from2 bacillus anthracis
61c2f1fA_
not modelled 22.2 15 PDB header:transferase
Chain: A: PDB Molecule:acetolactate synthase isozyme iii small subunit;
PDBTitle: crystal structure of the regulatory subunit of2 acetohydroxyacid synthase isozyme iii from e. coli
62c2bbjB_
not modelled 21.2 11 PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter
63d2cfxa2
not modelled 18.3 7 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
64c1w8xP_
not modelled 16.9 24 PDB header:virus
Chain: P: PDB Molecule:protein p16;
PDBTitle: structural analysis of prd1
65d1fe0a_
not modelled 16.8 14 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
66d1f7ua3
not modelled 16.6 10 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Family:Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
67c2k9yA_
not modelled 15.3 17 PDB header:transferase
Chain: A: PDB Molecule:ephrin type-a receptor 2;
PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0
68c2k9yB_
not modelled 15.3 17 PDB header:transferase
Chain: B: PDB Molecule:ephrin type-a receptor 2;
PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0
69d1nvmb2
not modelled 14.9 13 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:GAPDH-like
70d2cyya2
not modelled 14.4 9 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
71c3qlbA_
not modelled 14.1 8 PDB header:metal transport
Chain: A: PDB Molecule:enantio-pyochelin receptor;
PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin
72d2iuba2
not modelled 14.1 30 Fold:Transmembrane helix hairpin
Superfamily:Magnesium transport protein CorA, transmembrane region
Family:Magnesium transport protein CorA, transmembrane region
73d2phcb2
not modelled 14.0 13 Fold:DCoH-like
Superfamily:PH0987 N-terminal domain-like
Family:PH0987 N-terminal domain-like
74d1xhja_
not modelled 13.9 10 Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:NifU C-terminal domain-like
75c2hdiA_
not modelled 13.7 28 PDB header:protein transport,antimicrobial protein
Chain: A: PDB Molecule:colicin i receptor;
PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.
76c3lkxB_
not modelled 13.5 23 PDB header:chaperone
Chain: B: PDB Molecule:nascent polypeptide-associated complex subunit alpha;
PDBTitle: human nac dimerization domain
77c3bdeA_
not modelled 13.5 0 PDB header:unknown function
Chain: A: PDB Molecule:mll5499 protein;
PDBTitle: crystal structure of a dabb family protein with a ferredoxin-like fold2 (mll5499) from mesorhizobium loti maff303099 at 1.79 a resolution
78c3ibwA_
not modelled 13.3 29 PDB header:transferase
Chain: A: PDB Molecule:gtp pyrophosphokinase;
PDBTitle: crystal structure of the act domain from gtp2 pyrophosphokinase of chlorobium tepidum. northeast3 structural genomics consortium target ctr148a
79d1jb0i_
not modelled 13.3 19 Fold:Single transmembrane helix
Superfamily:Subunit VIII of photosystem I reaction centre, PsaI
Family:Subunit VIII of photosystem I reaction centre, PsaI
80c1a87A_
not modelled 13.3 15 PDB header:bacteriocin
Chain: A: PDB Molecule:colicin n;
PDBTitle: colicin n
81d1a87a_
not modelled 13.3 15 Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
82c2e1aD_
not modelled 13.3 14 PDB header:transcription
Chain: D: PDB Molecule:75aa long hypothetical regulatory protein asnc;
PDBTitle: crystal structure of ffrp-dm1
83d1qmga1
not modelled 13.2 25 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
84c2mltB_
not modelled 13.1 14 PDB header:toxin (hemolytic polypeptide)
Chain: B: PDB Molecule:melittin;
PDBTitle: melittin
85c2mltA_
not modelled 13.1 14 PDB header:toxin (hemolytic polypeptide)
Chain: A: PDB Molecule:melittin;
PDBTitle: melittin
86c2zbcH_
not modelled 12.7 16 PDB header:transcription
Chain: H: PDB Molecule:83aa long hypothetical transcriptional regulator asnc;
PDBTitle: crystal structure of sts042, a stand-alone ram module protein, from2 hyperthermophilic archaeon sulfolobus tokodaii strain7.
87c2kssA_
not modelled 12.5 24 PDB header:transcription regulator
Chain: A: PDB Molecule:carotenogenesis protein cars;
PDBTitle: nmr structure of myxococcus xanthus antirepressor cars1
88d2cg4a2
not modelled 12.5 16 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
89c2zztA_
not modelled 12.4 9 PDB header:transport protein
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of the cytosolic domain of the cation2 diffusion facilitator family protein
90d1ciia1
not modelled 12.3 13 Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
91c2pc6C_
not modelled 12.2 14 PDB header:lyase
Chain: C: PDB Molecule:probable acetolactate synthase isozyme iii (small subunit);
PDBTitle: crystal structure of putative acetolactate synthase- small subunit2 from nitrosomonas europaea
92c2z51A_
not modelled 12.1 13 PDB header:metal transport
Chain: A: PDB Molecule:nifu-like protein 2, chloroplast;
PDBTitle: crystal structure of arabidopsis cnfu involved in iron-2 sulfur cluster biosynthesis
93c2kncA_
not modelled 12.0 14 PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
94c3g7sA_
not modelled 11.4 17 PDB header:ligase
Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1);
PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus
95c2dvkA_
not modelled 11.4 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:upf0130 protein ape0816;
PDBTitle: crystal structure of hypothetical protein from aeropyrum pernix
96c2it3B_
not modelled 11.0 21 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:upf0130 protein ph1069;
PDBTitle: structure of ph1069 protein from pyrococcus horikoshii
97c3c6fD_
not modelled 10.9 4 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:yetf protein;
PDBTitle: crystal structure of protein bsu07140 from bacillus subtilis
98d2gufa1
not modelled 10.6 28 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
99c3aqoD_
not modelled 10.6 16 PDB header:membrane protein
Chain: D: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: structure and function of a membrane component secdf that enhances2 protein export

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0