Phyre 2 Results for P24177

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Email | l.a.kelley@imperial.ac.uk
Description | P24177
Date | Wed Jan 25 15:20:44 GMT 2012
Unique Job ID | 8137cd87d7d9248b

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c1oy8A_
Top template information
PDB header:membrane protein Chain: A: PDB Molecule:acriflavine resistance protein b; PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
Confidence and coverage
Confidence: | 100.0% | Coverage: | 97%
1005 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | A | N | F | F | I | D | R | P | I | F | A | W | V | L | A | I | L | L | C | L | T | G | T | L | A | I | F | S | L | P | V | E | Q | Y | P | D | L | A | P | P | N | V | R | V | T | A | N | Y | P | G | A | S | A | Q | T | L | E | N | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | V | T | Q | V | I | E | Q | N | M | T | G | L | D | N | L | M | Y | M | S | S | Q | S | S | G | T | G | Q | A | S | V | T | L | S | F | K | A | G | T | D | P | D | E | A | V | Q | Q | V | Q | N | Q | L | Q | S | A | M | R | K | L | P | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  | ? | ? |  |  |  |  |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | A | V | Q | N | Q | G | V | T | V | R | K | T | G | D | T | N | I | L | T | I | A | F | V | S | T | D | G | S | M | D | K | Q | D | I | A | D | Y | V | A | S | N | I | Q | D | P | L | S | R | V | N | G | V | G | D | I | D | A | Y | G | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  | ? |  |  | ? |  |  |  |  |  | ? | ? |  |  | ? |  |  |  |  |  |  |  |  |  | ? |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  | ? |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | Q | Y | S | M | R | I | W | L | D | P | A | K | L | N | S | F | Q | M | T | A | K | D | V | T | D | A | I | E | S | Q | N | A | Q | I | A | V | G | Q | L | G | G | T | P | S | V | D | K | Q | A | L | N | A | T | I | N | A | Q | S | L | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  | ? |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | Q | T | P | E | Q | F | R | D | I | T | L | R | V | N | Q | D | G | S | E | V | R | L | G | D | V | A | T | V | E | M | G | A | E | K | Y | D | Y | L | S | R | F | N | G | K | P | A | S | G | L | G | V | K | L | A | S | G | A | N | E | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  | ? |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | A | T | A | E | L | V | L | N | R | L | D | E | L | A | Q | Y | F | P | H | G | L | E | Y | K | V | A | Y | E | T | T | S | F | V | K | A | S | I | E | D | V | V | K | T | L | L | E | A | I | A | L | V | F | L | V | M | Y | L | F | L | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | N | F | R | A | T | L | I | P | T | I | A | V | P | V | V | L | M | G | T | F | S | V | L | Y | A | F | G | Y | S | V | N | T | L | T | M | F | A | M | V | L | A | I | G | L | L | V | D | D | A | I | V | V | V | E | N | V | E | R | I | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | S | E | E | G | L | T | P | R | E | A | T | R | K | S | M | G | Q | I | Q | G | A | L | V | G | I | A | M | V | L | S | A | V | F | V | P | M | A | F | F | G | G | T | T | G | A | I | Y | R | Q | F | S | I | T | I | V | A | A | M | V | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | S | V | L | V | A | M | I | L | T | P | A | L | C | A | T | L | L | K | P | L | K | K | G | E | H | H | G | Q | K | G | F | F | A | W | F | N | Q | M | F | N | R | N | A | E | R | Y | E | K | G | V | A | K | I | L | H | R | S | L | R | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600
Sequence |  | I | V | I | Y | V | L | L | L | G | G | M | V | F | L | F | L | R | L | P | T | S | F | L | P | L | E | D | R | G | M | F | T | T | S | V | Q | L | P | S | G | S | T | Q | Q | Q | T | L | K | V | V | E | Q | I | E | K | Y | Y | F | T | H
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660
Sequence |  | E | K | D | N | I | M | S | V | F | A | T | V | G | S | G | P | G | G | N | G | Q | N | V | A | R | M | F | I | R | L | K | D | W | S | E | R | D | S | K | T | G | T | S | F | A | I | I | E | R | A | T | K | A | F | N | Q | I | K | E | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720
Sequence |  | R | V | I | A | S | S | P | P | A | I | S | G | L | G | S | S | A | G | F | D | M | E | L | Q | D | H | A | G | A | G | H | D | A | L | M | A | A | R | N | Q | L | L | A | L | A | A | E | N | P | E | L | T | R | V | R | H | N | G | L | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  | ? |  | ? |  |  | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780
Sequence |  | D | S | P | Q | L | Q | I | D | I | D | Q | R | K | A | Q | A | L | G | V | A | I | D | D | I | N | D | T | L | Q | T | A | W | G | S | S | Y | V | N | D | F | M | D | R | G | R | V | K | K | V | Y | V | Q | A | A | A | P | Y | R | M | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840
Sequence |  | P | D | D | I | N | L | W | Y | V | R | N | K | D | G | G | M | V | P | F | S | A | F | A | T | S | R | W | E | T | G | S | P | R | L | E | R | Y | N | G | Y | S | A | V | E | I | V | G | E | A | A | P | G | V | S | T | G | T | A | M | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  |  |  | ? |  |  |  |  | ? |  |  |  | ? | ? |  |  |  | ? |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900
Sequence |  | I | M | E | S | L | V | K | Q | L | P | N | G | F | G | L | E | W | T | A | M | S | Y | Q | E | R | L | S | G | A | Q | A | P | A | L | Y | A | I | S | L | L | V | V | F | L | C | L | A | A | L | Y | E | S | W | S | V | P | F | S | V | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . | . | . | 960
Sequence |  | L | V | V | P | L | G | V | I | G | A | L | L | A | T | W | M | R | G | L | E | N | D | V | Y | F | Q | V | G | L | L | T | V | I | G | L | S | A | K | N | A | I | L | I | V | E | F | A | N | E | M | N | Q | K | G | H | D | L | F | E | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020
Sequence |  | T | L | H | A | C | R | Q | R | L | R | P | I | L | M | T | S | L | A | F | I | F | G | V | L | P | M | A | T | S | T | G | A | G | S | G | G | Q | H | A | V | G | T | G | V | M | G | G | M | I | S | A | T | I | L | A | I | Y | F | V | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | .
Sequence |  | L | F | F | V | L | V | R | R | R | F | P | L | K | P | R | P | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c1oy8A_ |

### PDB 1oy8 chain A

Region: 7 - 1033
Aligned: 1005
Modelled: 1027
Confidence: 100.0%
Identity: 66%
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump

Phyre2
2 |
| c3k07A_ |

### PDB 3k07 chain A

Region: 1 - 1027
Aligned: 999
Modelled: 1007
Confidence: 100.0%
Identity: 21%
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa

Phyre2
3 |
| c3aqpB_ |

### PDB 3aqp chain B

Region: 85 - 1029
Aligned: 675
Modelled: 715
Confidence: 100.0%
Identity: 16%
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus

Phyre2
4 |
| d1iwga8 |

### PDB 1iwg chain A domain 8

Region: 835 - 1033
Aligned: 199
Modelled: 199
Confidence: 100.0%
Identity: 68%
Fold: Multidrug efflux transporter AcrB transmembrane domain
Superfamily: Multidrug efflux transporter AcrB transmembrane domain
Family: Multidrug efflux transporter AcrB transmembrane domain

Phyre2
5 |
| d1iwga7 |

### PDB 1iwg chain A domain 7

Region: 306 - 498
Aligned: 193
Modelled: 193
Confidence: 100.0%
Identity: 79%
Fold: Multidrug efflux transporter AcrB transmembrane domain
Superfamily: Multidrug efflux transporter AcrB transmembrane domain
Family: Multidrug efflux transporter AcrB transmembrane domain

Phyre2
6 |
| d1iwga1 |

### PDB 1iwg chain A domain 1

Region: 38 - 134
Aligned: 97
Modelled: 97
Confidence: 99.8%
Identity: 61%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2
7 |
| d1iwga5 |

### PDB 1iwg chain A domain 5

Region: 182 - 273
Aligned: 92
Modelled: 92
Confidence: 99.5%
Identity: 59%
Fold: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains

Phyre2
8 |
| d1iwga2 |

### PDB 1iwg chain A domain 2

Region: 231 - 330
Aligned: 99
Modelled: 100
Confidence: 99.5%
Identity: 35%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2
9 |
| d1iwga6 |

### PDB 1iwg chain A domain 6

Region: 723 - 810
Aligned: 88
Modelled: 88
Confidence: 99.1%
Identity: 75%
Fold: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains

Phyre2
10 |
| d1iwga3 |

### PDB 1iwg chain A domain 3

Region: 567 - 672
Aligned: 106
Modelled: 106
Confidence: 98.9%
Identity: 49%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2
11 |
| d1iwga4 |

### PDB 1iwg chain A domain 4

Region: 673 - 857
Aligned: 97
Modelled: 97
Confidence: 98.3%
Identity: 64%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2
12 |
| c2ropA_ |

### PDB 2rop chain A

Region: 62 - 209
Aligned: 119
Modelled: 130
Confidence: 95.9%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of domains 3 and 4 of human atp7b

Phyre2
13 |
| c2ew9A_ |

### PDB 2ew9 chain A

Region: 62 - 209
Aligned: 122
Modelled: 148
Confidence: 95.7%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of apowln5-6

Phyre2
14 |
| c2rmlA_ |

### PDB 2rml chain A

Region: 62 - 209
Aligned: 114
Modelled: 127
Confidence: 93.7%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting p-type atpase copa;
PDBTitle: solution structure of the n-terminal soluble domains of2 bacillus subtilis copa

Phyre2
15 |
| d1s6ua_ |

### PDB 1s6u chain A

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 90.7%
Identity: 22%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2
16 |
| d2aw0a_ |

### PDB 2aw0 chain A

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 90.4%
Identity: 24%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2
17 |
| d1cpza_ |

### PDB 1cpz chain A

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 90.4%
Identity: 22%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2
18 |
| d2qifa1 |

### PDB 2qif chain A domain 1

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 89.8%
Identity: 22%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2
19 |
| c3dxsX_ |

### PDB 3dxs chain X

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 89.2%
Identity: 26%
PDB header:hydrolase
Chain: X: PDB Molecule:copper-transporting atpase ran1;
PDBTitle: crystal structure of a copper binding domain from hma7, a p-2 type atpase

Phyre2
20 |
| d1kvja_ |

### PDB 1kvj chain A

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 89.0%
Identity: 30%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2
21 |
22 |
23 |
24 |
25 |
26 |
27 |
28 |
29 |
30 |
31 |
32 |
33 |
34 |
35 |
36 |
37 |
38 |
39 |
40 |
41 |
42 |
43 |
44 |
45 |
46 |
47 |
48 |
49 |
50 |
51 |
52 |
53 |
54 |
55 |
56 |
57 |
58 |
59 |
60 |
61 |
62 |
63 |
64 |
65 |
66 |
67 |
68 |
69 |
70 |
71 |
72 |
73 |
74 |
75 |
76 |
77 |
78 |
79 |
80 |
81 |
82 |
83 |
84 |
85 |
86 |
87 |
88 |
89 |
90 |
91 |
92 |
93 |
94 |
95 |
96 |
97 |
98 |
99 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c1oy8A_ |
|  | 100.0 | 66 | PDB header:membrane protein Chain: A: PDB Molecule:acriflavine resistance protein b; PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
2 | c3k07A_ |
|  | 100.0 | 21 | PDB header:transport protein Chain: A: PDB Molecule:cation efflux system protein cusa; PDBTitle: crystal structure of cusa
3 | c3aqpB_ |
|  | 100.0 | 16 | PDB header:membrane protein Chain: B: PDB Molecule:probable secdf protein-export membrane protein; PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
4 | d1iwga8 |
|  | 100.0 | 68 | Fold:Multidrug efflux transporter AcrB transmembrane domain Superfamily:Multidrug efflux transporter AcrB transmembrane domain Family:Multidrug efflux transporter AcrB transmembrane domain
5 | d1iwga7 |
|  | 100.0 | 79 | Fold:Multidrug efflux transporter AcrB transmembrane domain Superfamily:Multidrug efflux transporter AcrB transmembrane domain Family:Multidrug efflux transporter AcrB transmembrane domain
6 | d1iwga1 |
|  | 99.8 | 61 | Fold:Ferredoxin-like Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
7 | d1iwga5 |
|  | 99.5 | 59 | Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
8 | d1iwga2 |
|  | 99.5 | 35 | Fold:Ferredoxin-like Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
9 | d1iwga6 |
|  | 99.1 | 75 | Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
10 | d1iwga3 |
|  | 98.9 | 49 | Fold:Ferredoxin-like Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
11 | d1iwga4 |
|  | 98.3 | 64 | Fold:Ferredoxin-like Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
12 | c2ropA_ |
|  | 95.9 | 18 | PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 2; PDBTitle: solution structure of domains 3 and 4 of human atp7b
13 | c2ew9A_ |
|  | 95.7 | 15 | PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 2; PDBTitle: solution structure of apowln5-6
14 | c2rmlA_ |
|  | 93.7 | 13 | PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting p-type atpase copa; PDBTitle: solution structure of the n-terminal soluble domains of2 bacillus subtilis copa
15 | d1s6ua_ |
|  | 90.7 | 22 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
16 | d2aw0a_ |
|  | 90.4 | 24 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
17 | d1cpza_ |
|  | 90.4 | 22 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
18 | d2qifa1 |
|  | 89.8 | 22 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
19 | c3dxsX_ |
|  | 89.2 | 26 | PDB header:hydrolase Chain: X: PDB Molecule:copper-transporting atpase ran1; PDBTitle: crystal structure of a copper binding domain from hma7, a p-2 type atpase
20 | d1kvja_ |
|  | 89.0 | 30 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
21 | c2l3mA_ |
| not modelled | 89.0 | 24 | PDB header:metal binding protein Chain: A: PDB Molecule:copper-ion-binding protein; PDBTitle: solution structure of the putative copper-ion-binding protein from2 bacillus anthracis str. ames
22 | d1q8la_ |
| not modelled | 88.4 | 22 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
23 | c1yjrA_ |
| not modelled | 87.7 | 22 | PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the apo form of the sixth soluble2 domain a69p mutant of menkes protein
24 | c2ga7A_ |
| not modelled | 87.3 | 28 | PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the copper(i) form of the third metal-2 binding domain of atp7a protein (menkes disease protein)
25 | d1p6ta2 |
| not modelled | 87.3 | 17 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
26 | c2ldiA_ |
| not modelled | 87.2 | 24 | PDB header:hydrolase Chain: A: PDB Molecule:zinc-transporting atpase; PDBTitle: nmr solution structure of ziaan sub mutant
27 | c2kkhA_ |
| not modelled | 86.0 | 15 | PDB header:metal transport Chain: A: PDB Molecule:putative heavy metal transporter; PDBTitle: structure of the zinc binding domain of the atpase hma4
28 | c1yg0A_ |
| not modelled | 85.5 | 22 | PDB header:metal transport Chain: A: PDB Molecule:cop associated protein; PDBTitle: solution structure of apo-copp from helicobacter pylori
29 | c2kt2A_ |
| not modelled | 85.2 | 18 | PDB header:oxidoreductase Chain: A: PDB Molecule:mercuric reductase; PDBTitle: structure of nmera, the n-terminal hma domain of tn501 mercuric2 reductase
30 | d1p6ta1 |
| not modelled | 85.2 | 24 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
31 | d1osda_ |
| not modelled | 84.7 | 22 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
32 | c2yvxD_ |
| not modelled | 84.2 | 15 | PDB header:transport protein Chain: D: PDB Molecule:mg2+ transporter mgte; PDBTitle: crystal structure of magnesium transporter mgte
33 | d1afia_ |
| not modelled | 84.1 | 20 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
34 | c2ofhX_ |
| not modelled | 81.7 | 20 | PDB header:hydrolase, membrane protein Chain: X: PDB Molecule:zinc-transporting atpase; PDBTitle: solution structure of the n-terminal domain of the zinc(ii) atpase2 ziaa in its apo form
35 | c1y3kA_ |
| not modelled | 80.4 | 20 | PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the apo form of the fifth domain of2 menkes protein
36 | d2ggpb1 |
| not modelled | 77.3 | 24 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
37 | d1mwza_ |
| not modelled | 75.7 | 14 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
38 | d1qupa2 |
| not modelled | 75.6 | 14 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
39 | c2gcfA_ |
| not modelled | 74.8 | 24 | PDB header:hydrolase Chain: A: PDB Molecule:cation-transporting atpase pacs; PDBTitle: solution structure of the n-terminal domain of the coppper(i) atpase2 pacs in its apo form
40 | c2k2pA_ |
| not modelled | 74.0 | 12 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu1203; PDBTitle: solution nmr structure of protein atu1203 from agrobacterium2 tumefaciens. northeast structural genomics consortium (nesg) target3 att10, ontario center for structural proteomics target atc1183
41 | c1jk9D_ |
| not modelled | 73.8 | 16 | PDB header:oxidoreductase Chain: D: PDB Molecule:copper chaperone for superoxide dismutase; PDBTitle: heterodimer between h48f-ysod1 and yccs
42 | c3j09A_ |
| not modelled | 73.5 | 17 | PDB header:hydrolase, metal transport Chain: A: PDB Molecule:copper-exporting p-type atpase a; PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa
43 | d1sb6a_ |
| not modelled | 70.9 | 12 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
44 | c2aj1A_ |
| not modelled | 70.4 | 9 | PDB header:hydrolase Chain: A: PDB Molecule:probable cadmium-transporting atpase; PDBTitle: solution structure of apocada
45 | c2rogA_ |
| not modelled | 69.8 | 16 | PDB header:metal binding protein Chain: A: PDB Molecule:heavy metal binding protein; PDBTitle: solution structure of thermus thermophilus hb8 ttha17182 protein in living e. coli cells
46 | c1qupA_ |
| not modelled | 64.6 | 14 | PDB header:chaperone Chain: A: PDB Molecule:superoxide dismutase 1 copper chaperone; PDBTitle: crystal structure of the copper chaperone for superoxide2 dismutase
47 | c2crlA_ |
| not modelled | 64.3 | 16 | PDB header:chaperone Chain: A: PDB Molecule:copper chaperone for superoxide dismutase; PDBTitle: the apo form of hma domain of copper chaperone for2 superoxide dismutase
48 | d1cc8a_ |
| not modelled | 57.1 | 12 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
49 | c1yj7A_ |
| not modelled | 53.8 | 19 | PDB header:protein transport Chain: A: PDB Molecule:escj; PDBTitle: crystal structure of enteropathogenic e.coli (epec) type iii secretion2 system protein escj
50 | d2nwwa1 |
| not modelled | 53.0 | 7 | Fold:Proton glutamate symport protein Superfamily:Proton glutamate symport protein Family:Proton glutamate symport protein
51 | c2kyzA_ |
| not modelled | 47.9 | 15 | PDB header:metal binding protein Chain: A: PDB Molecule:heavy metal binding protein; PDBTitle: nmr structure of heavy metal binding protein tm0320 from thermotoga2 maritima
52 | d1pw4a_ |
| not modelled | 43.9 | 7 | Fold:MFS general substrate transporter Superfamily:MFS general substrate transporter Family:Glycerol-3-phosphate transporter
53 | d2yvxa3 |
| not modelled | 42.5 | 16 | Fold:MgtE membrane domain-like Superfamily:MgtE membrane domain-like Family:MgtE membrane domain-like
54 | d2cu6a1 |
| not modelled | 42.3 | 18 | Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:PaaD-like
55 | d1uwda_ |
| not modelled | 39.7 | 18 | Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:PaaD-like
56 | c2yy3B_ |
| not modelled | 38.5 | 6 | PDB header:translation Chain: B: PDB Molecule:elongation factor 1-beta; PDBTitle: crystal structure of translation elongation factor ef-1 beta from2 pyrococcus horikoshii
57 | d2vv5a2 |
| not modelled | 34.0 | 18 | Fold:Ferredoxin-like Superfamily:Mechanosensitive channel protein MscS (YggB), C-terminal domain Family:Mechanosensitive channel protein MscS (YggB), C-terminal domain
58 | c1ciiA_ |
| not modelled | 31.3 | 15 | PDB header:transmembrane protein Chain: A: PDB Molecule:colicin ia; PDBTitle: colicin ia
59 | c3fryB_ |
| not modelled | 24.3 | 10 | PDB header:hydrolase Chain: B: PDB Molecule:probable copper-exporting p-type atpase a; PDBTitle: crystal structure of the copa c-terminal metal binding domain
60 | c3lnoA_ |
| not modelled | 23.7 | 19 | PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of domain of unknown function duf59 from2 bacillus anthracis
61 | c2f1fA_ |
| not modelled | 22.2 | 15 | PDB header:transferase Chain: A: PDB Molecule:acetolactate synthase isozyme iii small subunit; PDBTitle: crystal structure of the regulatory subunit of2 acetohydroxyacid synthase isozyme iii from e. coli
62 | c2bbjB_ |
| not modelled | 21.2 | 11 | PDB header:metal transport/membrane protein Chain: B: PDB Molecule:divalent cation transport-related protein; PDBTitle: crystal structure of the cora mg2+ transporter
63 | d2cfxa2 |
| not modelled | 18.3 | 7 | Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
64 | c1w8xP_ |
| not modelled | 16.9 | 24 | PDB header:virus Chain: P: PDB Molecule:protein p16; PDBTitle: structural analysis of prd1
65 | d1fe0a_ |
| not modelled | 16.8 | 14 | Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain
66 | d1f7ua3 |
| not modelled | 16.6 | 10 | Fold:RRF/tRNA synthetase additional domain-like Superfamily:Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Family:Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
67 | c2k9yA_ |
| not modelled | 15.3 | 17 | PDB header:transferase Chain: A: PDB Molecule:ephrin type-a receptor 2; PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0
68 | c2k9yB_ |
| not modelled | 15.3 | 17 | PDB header:transferase Chain: B: PDB Molecule:ephrin type-a receptor 2; PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0
69 | d1nvmb2 |
| not modelled | 14.9 | 13 | Fold:FwdE/GAPDH domain-like Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family:GAPDH-like
70 | d2cyya2 |
| not modelled | 14.4 | 9 | Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
71 | c3qlbA_ |
| not modelled | 14.1 | 8 | PDB header:metal transport Chain: A: PDB Molecule:enantio-pyochelin receptor; PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin
72 | d2iuba2 |
| not modelled | 14.1 | 30 | Fold:Transmembrane helix hairpin Superfamily:Magnesium transport protein CorA, transmembrane region Family:Magnesium transport protein CorA, transmembrane region
73 | d2phcb2 |
| not modelled | 14.0 | 13 | Fold:DCoH-like Superfamily:PH0987 N-terminal domain-like Family:PH0987 N-terminal domain-like
74 | d1xhja_ |
| not modelled | 13.9 | 10 | Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:NifU C-terminal domain-like
75 | c2hdiA_ |
| not modelled | 13.7 | 28 | PDB header:protein transport,antimicrobial protein Chain: A: PDB Molecule:colicin i receptor; PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.
76 | c3lkxB_ |
| not modelled | 13.5 | 23 | PDB header:chaperone Chain: B: PDB Molecule:nascent polypeptide-associated complex subunit alpha; PDBTitle: human nac dimerization domain
77 | c3bdeA_ |
| not modelled | 13.5 | 0 | PDB header:unknown function Chain: A: PDB Molecule:mll5499 protein; PDBTitle: crystal structure of a dabb family protein with a ferredoxin-like fold2 (mll5499) from mesorhizobium loti maff303099 at 1.79 a resolution
78 | c3ibwA_ |
| not modelled | 13.3 | 29 | PDB header:transferase Chain: A: PDB Molecule:gtp pyrophosphokinase; PDBTitle: crystal structure of the act domain from gtp2 pyrophosphokinase of chlorobium tepidum. northeast3 structural genomics consortium target ctr148a
79 | d1jb0i_ |
| not modelled | 13.3 | 19 | Fold:Single transmembrane helix Superfamily:Subunit VIII of photosystem I reaction centre, PsaI Family:Subunit VIII of photosystem I reaction centre, PsaI
80 | c1a87A_ |
| not modelled | 13.3 | 15 | PDB header:bacteriocin Chain: A: PDB Molecule:colicin n; PDBTitle: colicin n
81 | d1a87a_ |
| not modelled | 13.3 | 15 | Fold:Toxins' membrane translocation domains Superfamily:Colicin Family:Colicin
82 | c2e1aD_ |
| not modelled | 13.3 | 14 | PDB header:transcription Chain: D: PDB Molecule:75aa long hypothetical regulatory protein asnc; PDBTitle: crystal structure of ffrp-dm1
83 | d1qmga1 |
| not modelled | 13.2 | 25 | Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
84 | c2mltB_ |
| not modelled | 13.1 | 14 | PDB header:toxin (hemolytic polypeptide) Chain: B: PDB Molecule:melittin; PDBTitle: melittin
85 | c2mltA_ |
| not modelled | 13.1 | 14 | PDB header:toxin (hemolytic polypeptide) Chain: A: PDB Molecule:melittin; PDBTitle: melittin
86 | c2zbcH_ |
| not modelled | 12.7 | 16 | PDB header:transcription Chain: H: PDB Molecule:83aa long hypothetical transcriptional regulator asnc; PDBTitle: crystal structure of sts042, a stand-alone ram module protein, from2 hyperthermophilic archaeon sulfolobus tokodaii strain7.
87 | c2kssA_ |
| not modelled | 12.5 | 24 | PDB header:transcription regulator Chain: A: PDB Molecule:carotenogenesis protein cars; PDBTitle: nmr structure of myxococcus xanthus antirepressor cars1
88 | d2cg4a2 |
| not modelled | 12.5 | 16 | Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
89 | c2zztA_ |
| not modelled | 12.4 | 9 | PDB header:transport protein Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the cytosolic domain of the cation2 diffusion facilitator family protein
90 | d1ciia1 |
| not modelled | 12.3 | 13 | Fold:Toxins' membrane translocation domains Superfamily:Colicin Family:Colicin
91 | c2pc6C_ |
| not modelled | 12.2 | 14 | PDB header:lyase Chain: C: PDB Molecule:probable acetolactate synthase isozyme iii (small subunit); PDBTitle: crystal structure of putative acetolactate synthase- small subunit2 from nitrosomonas europaea
92 | c2z51A_ |
| not modelled | 12.1 | 13 | PDB header:metal transport Chain: A: PDB Molecule:nifu-like protein 2, chloroplast; PDBTitle: crystal structure of arabidopsis cnfu involved in iron-2 sulfur cluster biosynthesis
93 | c2kncA_ |
| not modelled | 12.0 | 14 | PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
94 | c3g7sA_ |
| not modelled | 11.4 | 17 | PDB header:ligase Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1); PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus
95 | c2dvkA_ |
| not modelled | 11.4 | 21 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0130 protein ape0816; PDBTitle: crystal structure of hypothetical protein from aeropyrum pernix
96 | c2it3B_ |
| not modelled | 11.0 | 21 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:upf0130 protein ph1069; PDBTitle: structure of ph1069 protein from pyrococcus horikoshii
97 | c3c6fD_ |
| not modelled | 10.9 | 4 | PDB header:structural genomics, unknown function Chain: D: PDB Molecule:yetf protein; PDBTitle: crystal structure of protein bsu07140 from bacillus subtilis
98 | d2gufa1 |
| not modelled | 10.6 | 28 | Fold:Transmembrane beta-barrels Superfamily:Porins Family:Ligand-gated protein channel
99 | c3aqoD_ |
| not modelled | 10.6 | 16 | PDB header:membrane protein Chain: D: PDB Molecule:probable secdf protein-export membrane protein; PDBTitle: structure and function of a membrane component secdf that enhances2 protein export

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0