Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP16869
DateThu Jan 5 11:35:50 GMT 2012
Unique Job ID7d663c12e5e415d6

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2iahA_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:ferripyoverdine receptor;
PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine.
Confidence and coverage
Confidence:100.0% Coverage: 95%
692 residues ( 95% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLSTQFNRDNQYQAITKPSLLAGCIALALLPSAAFAAPATEETVIVEGSATAPDDGENDY
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   .........70.........80.........90.........100.........110.........120
Sequence  SVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVMENTLGISKSQADSDRALY
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   .........130.........140.........150.........160.........170.........180
Sequence  YSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEVVRGATGLMTGTGNPSAAINM
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   .........190.........200.........210.........220.........230.........240
Sequence  VRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRYNS
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   .........250.........260.........270.........280.........290.........300
Sequence  EKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTWGGLPRWNTDGSSNSYDRARSTAPDW
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   .........310.........320.........330.........340.........350.........360
Sequence  AYNDKEINKVFMTLKQQFADTWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPYSNY
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   .........370.........380.........390.........400.........410.........420
Sequence  GPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGRQHNLMFGGSYSKQNNRYFSSWANIF
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   .........430.........440.........450.........460.........470.........480
Sequence  PDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRV
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   .........490.........500.........510.........520.........530.........540
Sequence  DTLTYSMEKNHTTPYAGLVFDINDNWSTYASYTSIFQPQNDRDSSGKYLAPITGNNYELG
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   .........550.........560.........570.........580.........590.........600
Sequence  LKSDWMNSRLTTTLAIFRIEQDNVAQSTGTPIPGSNGETAYKAVDGTVSKGVEFELNGAI
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   .........610.........620.........630.........640.........650.........660
Sequence  TDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYT
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   .........670.........680.........690.........700.........710.........720
Sequence  DTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGTPRN
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??
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   .........
Sequence  FSITGTYQF
Secondary structure 
SS confidence 








Disorder 







?
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2iah chain A

3D model

Region: 24 - 729
Aligned: 692
Modelled: 706
Confidence: 100.0%
Identity: 31%
PDB header:membrane protein
Chain: A: PDB Molecule:ferripyoverdine receptor;
PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine.

Phyre2

PDB 1xkh chain C

3D model

Region: 42 - 729
Aligned: 676
Modelled: 664
Confidence: 100.0%
Identity: 31%
PDB header:membrane protein
Chain: C: PDB Molecule:ferripyoverdine receptor;
PDBTitle: pyoverdine outer membrane receptor fpva from pseudomonas aeruginosa2 pao1 bound to pyoverdine

Phyre2

PDB 3qlb chain A

3D model

Region: 50 - 729
Aligned: 649
Modelled: 665
Confidence: 100.0%
Identity: 19%
PDB header:metal transport
Chain: A: PDB Molecule:enantio-pyochelin receptor;
PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin

Phyre2

PDB 2grx chain B

3D model

Region: 51 - 729
Aligned: 664
Modelled: 664
Confidence: 100.0%
Identity: 18%
PDB header:metal transport
Chain: B: PDB Molecule:ferrichrome-iron receptor;
PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome

Phyre2

PDB 1by5 chain A

3D model

Region: 50 - 729
Aligned: 664
Modelled: 680
Confidence: 100.0%
Identity: 19%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 1xkw chain A

3D model

Region: 55 - 729
Aligned: 644
Modelled: 662
Confidence: 100.0%
Identity: 27%
PDB header:membrane protein
Chain: A: PDB Molecule:fe(iii)-pyochelin receptor;
PDBTitle: pyochelin outer membrane receptor fpta from pseudomonas2 aeruginosa

Phyre2

PDB 3efm chain A

3D model

Region: 49 - 711
Aligned: 565
Modelled: 585
Confidence: 100.0%
Identity: 38%
PDB header:membrane protein
Chain: A: PDB Molecule:ferric alcaligin siderophore receptor;
PDBTitle: structure of the alcaligin outer membrane recepteur faua from2 bordetella pertussis

Phyre2

PDB 3fhh chain A

3D model

Region: 62 - 729
Aligned: 589
Modelled: 607
Confidence: 100.0%
Identity: 17%
PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane heme receptor shua;
PDBTitle: crystal structure of the heme/hemoglobin outer membrane2 transporter shua from shigella dysenteriae

Phyre2

PDB 1kmo chain A

3D model

Region: 63 - 729
Aligned: 622
Modelled: 632
Confidence: 100.0%
Identity: 16%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 2hdi chain A

3D model

Region: 62 - 729
Aligned: 560
Modelled: 568
Confidence: 100.0%
Identity: 18%
PDB header:protein transport,antimicrobial protein
Chain: A: PDB Molecule:colicin i receptor;
PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.

Phyre2

PDB 2guf chain A domain 1

3D model

Region: 62 - 729
Aligned: 539
Modelled: 574
Confidence: 100.0%
Identity: 15%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 1po3 chain A

3D model

Region: 73 - 729
Aligned: 612
Modelled: 622
Confidence: 100.0%
Identity: 15%
PDB header:membrane protein
Chain: A: PDB Molecule:iron(iii) dicitrate transport protein feca
PDBTitle: crystal structure of ferric citrate transporter feca in2 complex with ferric citrate

Phyre2

PDB 3csl chain B

3D model

Region: 72 - 729
Aligned: 637
Modelled: 637
Confidence: 100.0%
Identity: 17%
PDB header:membrane protein/heme binding protein
Chain: B: PDB Molecule:hasr protein;
PDBTitle: structure of the serratia marcescens hemophore receptor hasr in2 complex with its hemophore hasa and heme

Phyre2

PDB 1fep chain A

3D model

Region: 62 - 729
Aligned: 626
Modelled: 626
Confidence: 100.0%
Identity: 15%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 1t16 chain A

3D model

Region: 453 - 729
Aligned: 271
Modelled: 277
Confidence: 99.4%
Identity: 12%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Outer membrane protein transport protein

Phyre2

PDB 3dwo chain X

3D model

Region: 436 - 688
Aligned: 249
Modelled: 253
Confidence: 99.2%
Identity: 16%
PDB header:membrane protein
Chain: X: PDB Molecule:probable outer membrane protein;
PDBTitle: crystal structure of a pseudomonas aeruginosa fadl homologue

Phyre2

PDB 2k0l chain A

3D model

Region: 591 - 729
Aligned: 136
Modelled: 139
Confidence: 97.6%
Identity: 12%
PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein a;
PDBTitle: nmr structure of the transmembrane domain of the outer2 membrane protein a from klebsiella pneumoniae in dhpc3 micelles.

Phyre2

PDB 3brz chain A

3D model

Region: 446 - 687
Aligned: 227
Modelled: 242
Confidence: 97.4%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:todx;
PDBTitle: crystal structure of the pseudomonas putida toluene2 transporter todx

Phyre2

PDB 3qra chain A

3D model

Region: 590 - 729
Aligned: 125
Modelled: 140
Confidence: 97.3%
Identity: 11%
PDB header:cell invasion
Chain: A: PDB Molecule:attachment invasion locus protein;
PDBTitle: the crystal structure of ail, the attachment invasion locus protein of2 yersinia pestis

Phyre2

PDB 1g90 chain A

3D model

Region: 590 - 729
Aligned: 136
Modelled: 140
Confidence: 97.1%
Identity: 12%
Fold: Transmembrane beta-barrels
Superfamily: OMPA-like
Family: Outer membrane protein

Phyre2
1

c2iahA_
2

c1xkhC_
3

c3qlbA_
4

c2grxB_
5

d1by5a_
6

c1xkwA_
7

c3efmA_
8

c3fhhA_
9

d1kmoa_
10

c2hdiA_
11

d2gufa1
12

c1po3A_
13

c3cslB_
14

d1fepa_
15

d1t16a_
16

c3dwoX_
17

c2k0lA_
18

c3brzA_
19

c3qraA_
20

d1g90a_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2iahA_



100.0 31 PDB header:membrane protein
Chain: A: PDB Molecule:ferripyoverdine receptor;
PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine.
2c1xkhC_



100.0 31 PDB header:membrane protein
Chain: C: PDB Molecule:ferripyoverdine receptor;
PDBTitle: pyoverdine outer membrane receptor fpva from pseudomonas aeruginosa2 pao1 bound to pyoverdine
3c3qlbA_



100.0 19 PDB header:metal transport
Chain: A: PDB Molecule:enantio-pyochelin receptor;
PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin
4c2grxB_



100.0 18 PDB header:metal transport
Chain: B: PDB Molecule:ferrichrome-iron receptor;
PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome
5d1by5a_



100.0 19 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
6c1xkwA_



100.0 27 PDB header:membrane protein
Chain: A: PDB Molecule:fe(iii)-pyochelin receptor;
PDBTitle: pyochelin outer membrane receptor fpta from pseudomonas2 aeruginosa
7c3efmA_



100.0 38 PDB header:membrane protein
Chain: A: PDB Molecule:ferric alcaligin siderophore receptor;
PDBTitle: structure of the alcaligin outer membrane recepteur faua from2 bordetella pertussis
8c3fhhA_



100.0 17 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane heme receptor shua;
PDBTitle: crystal structure of the heme/hemoglobin outer membrane2 transporter shua from shigella dysenteriae
9d1kmoa_



100.0 16 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
10c2hdiA_



100.0 18 PDB header:protein transport,antimicrobial protein
Chain: A: PDB Molecule:colicin i receptor;
PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.
11d2gufa1



100.0 15 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
12c1po3A_



100.0 15 PDB header:membrane protein
Chain: A: PDB Molecule:iron(iii) dicitrate transport protein feca
PDBTitle: crystal structure of ferric citrate transporter feca in2 complex with ferric citrate
13c3cslB_



100.0 17 PDB header:membrane protein/heme binding protein
Chain: B: PDB Molecule:hasr protein;
PDBTitle: structure of the serratia marcescens hemophore receptor hasr in2 complex with its hemophore hasa and heme
14d1fepa_



100.0 15 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
15d1t16a_



99.4 12 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Outer membrane protein transport protein
16c3dwoX_



99.2 16 PDB header:membrane protein
Chain: X: PDB Molecule:probable outer membrane protein;
PDBTitle: crystal structure of a pseudomonas aeruginosa fadl homologue
17c2k0lA_



97.6 12 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein a;
PDBTitle: nmr structure of the transmembrane domain of the outer2 membrane protein a from klebsiella pneumoniae in dhpc3 micelles.
18c3brzA_



97.4 11 PDB header:transport protein
Chain: A: PDB Molecule:todx;
PDBTitle: crystal structure of the pseudomonas putida toluene2 transporter todx
19c3qraA_



97.3 11 PDB header:cell invasion
Chain: A: PDB Molecule:attachment invasion locus protein;
PDBTitle: the crystal structure of ail, the attachment invasion locus protein of2 yersinia pestis
20d1g90a_



97.1 12 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
21c2f1tB_



not modelled 96.8 12 PDB header:membrane protein
Chain: B: PDB Molecule:outer membrane protein w;
PDBTitle: outer membrane protein ompw
22c3nb3C_



not modelled 96.2 12 PDB header:virus
Chain: C: PDB Molecule:outer membrane protein a;
PDBTitle: the host outer membrane proteins ompa and ompc are packed at specific2 sites in the shigella phage sf6 virion as structural components
23d1qjpa_



not modelled 95.9 14 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
24c3bryB_



not modelled 95.3 14 PDB header:transport protein
Chain: B: PDB Molecule:tbux;
PDBTitle: crystal structure of the ralstonia pickettii toluene2 transporter tbux
25c2x27X_



not modelled 92.9 12 PDB header:membrane protein
Chain: X: PDB Molecule:outer membrane protein oprg;
PDBTitle: crystal structure of the outer membrane protein oprg from2 pseudomonas aeruginosa
26d1qj8a_



not modelled 92.5 10 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
27d1p4ta_



not modelled 92.3 12 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
28c2jmmA_



not modelled 90.1 11 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein a;
PDBTitle: nmr solution structure of a minimal transmembrane beta-2 barrel platform protein
29c2iwvD_



not modelled 89.1 12 PDB header:ion channel
Chain: D: PDB Molecule:outer membrane protein g;
PDBTitle: structure of the monomeric outer membrane porin ompg in the2 open and closed conformation
30c3kvnA_



not modelled 88.7 12 PDB header:hydrolase
Chain: A: PDB Molecule:esterase esta;
PDBTitle: crystal structure of the full-length autotransporter esta from2 pseudomonas aeruginosa
31d2fgqx1



not modelled 82.1 13 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Porin
32c3sljA_



not modelled 78.0 14 PDB header:protein transport
Chain: A: PDB Molecule:serine protease espp;
PDBTitle: pre-cleavage structure of the autotransporter espp - n1023a mutant
33d1phoa_



not modelled 74.6 13 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Porin
34c3aehB_



not modelled 69.3 15 PDB header:hydrolase
Chain: B: PDB Molecule:hemoglobin-binding protease hbp autotransporter;
PDBTitle: integral membrane domain of autotransporter hbp
35d1osma_



not modelled 65.8 14 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Porin
36c2wjqA_



not modelled 54.0 7 PDB header:transport protein
Chain: A: PDB Molecule:probable n-acetylneuraminic acid outer membrane channel
PDBTitle: nanc porin structure in hexagonal crystal form.
37d1uynx_



not modelled 50.5 8 Fold:Transmembrane beta-barrels
Superfamily:Autotransporter
Family:Autotransporter
38c2qomB_



not modelled 48.2 13 PDB header:hydrolase
Chain: B: PDB Molecule:serine protease espp;
PDBTitle: the crystal structure of the e.coli espp autotransporter beta-domain.
39c2y0kA_



not modelled 44.0 13 PDB header:transport protein
Chain: A: PDB Molecule:pyroglutatmate porin opdo;
PDBTitle: crystal structure of pseudomonas aeruginosa opdo
40d2zfga1



not modelled 33.9 12 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Porin
41c2lhfA_



not modelled 32.7 11 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein h1;
PDBTitle: solution structure of outer membrane protein h (oprh) from p.2 aeruginosa in dhpc micelles
42c2x4mD_



not modelled 27.8 14 PDB header:hydrolase
Chain: D: PDB Molecule:coagulase/fibrinolysin;
PDBTitle: yersinia pestis plasminogen activator pla
43c3qq2C_



not modelled 25.2 11 PDB header:membrane protein/protein transport
Chain: C: PDB Molecule:brka autotransporter;
PDBTitle: crystal structure of the beta domain of the bordetella autotransporter2 brka
44d1i78a_



not modelled 22.3 15 Fold:Transmembrane beta-barrels
Superfamily:OMPT-like
Family:Outer membrane protease OMPT
45d2a1ja1



not modelled 20.3 10 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
46c2o4vA_



not modelled 14.8 11 PDB header:membrane protein
Chain: A: PDB Molecule:porin p;
PDBTitle: an arginine ladder in oprp mediates phosphate specific transfer across2 the outer membrane
47c3a2rX_



not modelled 11.5 15 PDB header:membrane protein
Chain: X: PDB Molecule:outer membrane protein ii;
PDBTitle: crystal structure of outer membrane protein porb from neisseria2 meningitidis
48c1wx4B_



not modelled 6.9 24 PDB header:oxidoreductase/metal transport
Chain: B: PDB Molecule:melc;
PDBTitle: crystal structure of the oxy-form of the copper-bound streptomyces2 castaneoglobisporus tyrosinase complexed with a caddie protein3 prepared by the addition of dithiothreitol
49c3nsgA_



not modelled 6.6 8 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein f;
PDBTitle: crystal structure of ompf, an outer membrane protein from salmonella2 typhi
50c3rbhC_



not modelled 6.0 11 PDB header:transport protein
Chain: C: PDB Molecule:alginate production protein alge;
PDBTitle: structure of alginate export protein alge from pseudomonas aeruginosa
51c2vdaB_



not modelled 5.9 29 PDB header:protein transport
Chain: B: PDB Molecule:maltoporin;
PDBTitle: solution structure of the seca-signal peptide complex
52c2w3pB_



not modelled 5.4 11 PDB header:lyase
Chain: B: PDB Molecule:benzoyl-coa-dihydrodiol lyase;
PDBTitle: boxc crystal structure
53c3jtyB_



not modelled 5.3 10 PDB header:transport protein
Chain: B: PDB Molecule:benf-like porin;
PDBTitle: crystal structure of a benf-like porin from pseudomonas fluorescens2 pf-5

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0