Phyre 2 Results for P75780

Email	l.a.kelley@imperial.ac.uk
Description	P75780
Date	Thu Jan 5 12:14:03 GMT 2012
Unique Job ID	7aa9862a22a22ae6

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2iahA_

Top template information

PDB header:membrane protein
Chain: A: PDB Molecule:ferripyoverdine receptor;
PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine.

Confidence and coverage

Confidence:

100.0%

Coverage:

89%

677 residues ( 89% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M E N N R N F P A R Q F H S L T F F A G L C I G I T P V A Q A L A A E G Q T N A D D T L V V E A S T P S L Y A P Q Q S A

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence D P K F S R P V A D T T R T M T V I S E Q V I K D Q G A T N L T D A L K N V P G V G A F F A G E N G N S T T G D A I Y M

Secondary structure

SS confidence

Disorder ? ? ? ? ?
?
?
? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence R G A D T S N S I Y I D G I R D I G S V S R D T F N T E Q V E V I K G P S G T D Y G R S A P T G S I N M I S K Q P R N D

Secondary structure

SS confidence

Disorder
? ? ?
? ?
?
?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence S G I D A S A S I G S A W F R R G T L D V N Q V I G D T T A V R L N V M G E K T H D A G R D K V K N E R Y G V A P S V A

Secondary structure

SS confidence

Disorder ?
?
? ? ?
?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence F G L G T A N R L Y L N Y L H V T Q H N T P D G G I P T I G L P G Y S A P S A G T A A L N H S G K V D T H N F Y G T D S

Secondary structure

SS confidence

Disorder
?
?
? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ?
?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence D Y D D S T T D T A T M R F E H D I N D N T T I R N T T R W S R V K Q D Y L M T A I M G G A S N I T Q P T S D V N S W T

Secondary structure

SS confidence

Disorder
? ?
? ? ? ? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence W S R T A N T K D V S N K I L T N Q T N L T S T F Y T G S I G H D V S T G V E F T R E T Q T N Y G V N P V T L P A V N I

Secondary structure

SS confidence

Disorder
? ? ? ?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence Y H P D S S I H P G G L T R N G A N A N G Q T D T F A I Y A F D T L Q I T R D F E L N G G I R L D N Y H T E Y D S A T A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence C G G S G R G A I T C P T G V A K G S P V T T V D T A K S G N L M N W K A G A L Y H L T E N G N V Y I N Y A V S Q Q P P

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence G G N N F A L A Q S G S G N S A N R T D F K P Q K A N T S E I G T K W Q V L D K R L L L T A A L F R T D I E N E V E Q N

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence D D G T Y S Q Y G K K R V E G Y E I S V A G N I T P A W Q V I G G Y T Q Q K A T I K N G K D V A Q D G S S S L P Y T P E

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence H A F T L W S Q Y Q A T D D I S V G A G A R Y I G S M H K G S D G A V G T P A F T E G Y W V A D A K L G Y R V N R N L D

Secondary structure

SS confidence

Disorder
?
?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760

Sequence F Q L N V Y N L F D T D Y V A S I N K S G Y R Y H P G E P R T F L L T A N M H F

Secondary structure

SS confidence

Disorder
?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2iah chain A

Region: 17 - 760
Aligned: 677
Modelled: 698
Confidence: 100.0%
Identity: 20%
PDB header:membrane protein
Chain: A: PDB Molecule:ferripyoverdine receptor;
PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine.

Phyre2

PDB 3qlb chain A

Region: 43 - 760
Aligned: 658
Modelled: 668
Confidence: 100.0%
Identity: 18%
PDB header:metal transport
Chain: A: PDB Molecule:enantio-pyochelin receptor;
PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin

Phyre2

PDB 2grx chain B

Region: 47 - 760
Aligned: 670
Modelled: 670
Confidence: 100.0%
Identity: 20%
PDB header:metal transport
Chain: B: PDB Molecule:ferrichrome-iron receptor;
PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome

Phyre2

PDB 1by5 chain A

Region: 47 - 760
Aligned: 669
Modelled: 692
Confidence: 100.0%
Identity: 20%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 1xkh chain C

Region: 33 - 760
Aligned: 660
Modelled: 648
Confidence: 100.0%
Identity: 21%
PDB header:membrane protein
Chain: C: PDB Molecule:ferripyoverdine receptor;
PDBTitle: pyoverdine outer membrane receptor fpva from pseudomonas aeruginosa2 pao1 bound to pyoverdine

Phyre2

PDB 1xkw chain A

Region: 49 - 760
Aligned: 640
Modelled: 650
Confidence: 100.0%
Identity: 21%
PDB header:membrane protein
Chain: A: PDB Molecule:fe(iii)-pyochelin receptor;
PDBTitle: pyochelin outer membrane receptor fpta from pseudomonas2 aeruginosa

Phyre2

PDB 3fhh chain A

Region: 54 - 760
Aligned: 581
Modelled: 601
Confidence: 100.0%
Identity: 18%
PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane heme receptor shua;
PDBTitle: crystal structure of the heme/hemoglobin outer membrane2 transporter shua from shigella dysenteriae

Phyre2

PDB 1kmo chain A

Region: 56 - 760
Aligned: 622
Modelled: 643
Confidence: 100.0%
Identity: 18%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 3efm chain A

Region: 46 - 739
Aligned: 549
Modelled: 580
Confidence: 100.0%
Identity: 20%
PDB header:membrane protein
Chain: A: PDB Molecule:ferric alcaligin siderophore receptor;
PDBTitle: structure of the alcaligin outer membrane recepteur faua from2 bordetella pertussis

Phyre2

PDB 1po3 chain A

Region: 66 - 760
Aligned: 612
Modelled: 633
Confidence: 100.0%
Identity: 18%
PDB header:membrane protein
Chain: A: PDB Molecule:iron(iii) dicitrate transport protein feca
PDBTitle: crystal structure of ferric citrate transporter feca in2 complex with ferric citrate

Phyre2

PDB 3csl chain B

Region: 65 - 760
Aligned: 669
Modelled: 675
Confidence: 100.0%
Identity: 17%
PDB header:membrane protein/heme binding protein
Chain: B: PDB Molecule:hasr protein;
PDBTitle: structure of the serratia marcescens hemophore receptor hasr in2 complex with its hemophore hasa and heme

Phyre2

PDB 1fep chain A

Region: 55 - 760
Aligned: 624
Modelled: 628
Confidence: 100.0%
Identity: 16%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 2guf chain A domain 1

Region: 53 - 760
Aligned: 537
Modelled: 567
Confidence: 100.0%
Identity: 18%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2

PDB 2hdi chain A

Region: 55 - 760
Aligned: 550
Modelled: 575
Confidence: 100.0%
Identity: 19%
PDB header:protein transport,antimicrobial protein
Chain: A: PDB Molecule:colicin i receptor;
PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.

Phyre2

PDB 1t16 chain A

Region: 429 - 760
Aligned: 294
Modelled: 297
Confidence: 99.7%
Identity: 12%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Outer membrane protein transport protein

Phyre2

PDB 3dwo chain X

Region: 439 - 716
Aligned: 272
Modelled: 278
Confidence: 99.4%
Identity: 12%
PDB header:membrane protein
Chain: X: PDB Molecule:probable outer membrane protein;
PDBTitle: crystal structure of a pseudomonas aeruginosa fadl homologue

Phyre2

PDB 3brz chain A

Region: 437 - 715
Aligned: 260
Modelled: 279
Confidence: 98.6%
Identity: 12%
PDB header:transport protein
Chain: A: PDB Molecule:todx;
PDBTitle: crystal structure of the pseudomonas putida toluene2 transporter todx

Phyre2

PDB 3bry chain B

Region: 409 - 714
Aligned: 273
Modelled: 286
Confidence: 97.0%
Identity: 10%
PDB header:transport protein
Chain: B: PDB Molecule:tbux;
PDBTitle: crystal structure of the ralstonia pickettii toluene2 transporter tbux

Phyre2

PDB 2f1t chain B

Region: 615 - 760
Aligned: 141
Modelled: 144
Confidence: 96.4%
Identity: 13%
PDB header:membrane protein
Chain: B: PDB Molecule:outer membrane protein w;
PDBTitle: outer membrane protein ompw

Phyre2

PDB 2fgq chain X domain 1

Region: 536 - 760
Aligned: 189
Modelled: 224
Confidence: 96.1%
Identity: 12%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Porin

Phyre2

Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	E	N	N	R	N	F	P	A	R	Q	F	H	S	L	T	F	F	A	G	L	C	I	G	I	T	P	V	A	Q	A	L	A	A	E	G	Q	T	N	A	D	D	T	L	V	V	E	A	S	T	P	S	L	Y	A	P	Q	Q	S	A
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?	?	?															?	?	?	?	?	?	?	?	?	?	?	?	?										?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	D	P	K	F	S	R	P	V	A	D	T	T	R	T	M	T	V	I	S	E	Q	V	I	K	D	Q	G	A	T	N	L	T	D	A	L	K	N	V	P	G	V	G	A	F	F	A	G	E	N	G	N	S	T	T	G	D	A	I	Y	M
Secondary structure
SS confidence
Disorder	?	?	?	?	?																							?													?			?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	R	G	A	D	T	S	N	S	I	Y	I	D	G	I	R	D	I	G	S	V	S	R	D	T	F	N	T	E	Q	V	E	V	I	K	G	P	S	G	T	D	Y	G	R	S	A	P	T	G	S	I	N	M	I	S	K	Q	P	R	N	D
Secondary structure
SS confidence
Disorder																	?	?	?			?	?																?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	S	G	I	D	A	S	A	S	I	G	S	A	W	F	R	R	G	T	L	D	V	N	Q	V	I	G	D	T	T	A	V	R	L	N	V	M	G	E	K	T	H	D	A	G	R	D	K	V	K	N	E	R	Y	G	V	A	P	S	V	A
Secondary structure
SS confidence
Disorder	?																																							?		?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	F	G	L	G	T	A	N	R	L	Y	L	N	Y	L	H	V	T	Q	H	N	T	P	D	G	G	I	P	T	I	G	L	P	G	Y	S	A	P	S	A	G	T	A	A	L	N	H	S	G	K	V	D	T	H	N	F	Y	G	T	D	S
Secondary structure
SS confidence
Disorder																		?			?										?	?	?	?	?	?	?	?	?	?	?	?		?	?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	D	Y	D	D	S	T	T	D	T	A	T	M	R	F	E	H	D	I	N	D	N	T	T	I	R	N	T	T	R	W	S	R	V	K	Q	D	Y	L	M	T	A	I	M	G	G	A	S	N	I	T	Q	P	T	S	D	V	N	S	W	T
Secondary structure
SS confidence
Disorder																																		?	?										?	?	?	?	?	?	?	?	?			?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	W	S	R	T	A	N	T	K	D	V	S	N	K	I	L	T	N	Q	T	N	L	T	S	T	F	Y	T	G	S	I	G	H	D	V	S	T	G	V	E	F	T	R	E	T	Q	T	N	Y	G	V	N	P	V	T	L	P	A	V	N	I
Secondary structure
SS confidence
Disorder							?	?	?	?																																			?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence	Y	H	P	D	S	S	I	H	P	G	G	L	T	R	N	G	A	N	A	N	G	Q	T	D	T	F	A	I	Y	A	F	D	T	L	Q	I	T	R	D	F	E	L	N	G	G	I	R	L	D	N	Y	H	T	E	Y	D	S	A	T	A
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?	?	?	?																																			?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence	C	G	G	S	G	R	G	A	I	T	C	P	T	G	V	A	K	G	S	P	V	T	T	V	D	T	A	K	S	G	N	L	M	N	W	K	A	G	A	L	Y	H	L	T	E	N	G	N	V	Y	I	N	Y	A	V	S	Q	Q	P	P
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																															?
Disorder confidence

	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence	G	G	N	N	F	A	L	A	Q	S	G	S	G	N	S	A	N	R	T	D	F	K	P	Q	K	A	N	T	S	E	I	G	T	K	W	Q	V	L	D	K	R	L	L	L	T	A	A	L	F	R	T	D	I	E	N	E	V	E	Q	N
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?				?
Disorder confidence

	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence	D	D	G	T	Y	S	Q	Y	G	K	K	R	V	E	G	Y	E	I	S	V	A	G	N	I	T	P	A	W	Q	V	I	G	G	Y	T	Q	Q	K	A	T	I	K	N	G	K	D	V	A	Q	D	G	S	S	S	L	P	Y	T	P	E
Secondary structure
SS confidence
Disorder																																												?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence	H	A	F	T	L	W	S	Q	Y	Q	A	T	D	D	I	S	V	G	A	G	A	R	Y	I	G	S	M	H	K	G	S	D	G	A	V	G	T	P	A	F	T	E	G	Y	W	V	A	D	A	K	L	G	Y	R	V	N	R	N	L	D
Secondary structure
SS confidence
Disorder																															?						?
Disorder confidence

	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760
Sequence	F	Q	L	N	V	Y	N	L	F	D	T	D	Y	V	A	S	I	N	K	S	G	Y	R	Y	H	P	G	E	P	R	T	F	L	L	T	A	N	M	H	F
Secondary structure
SS confidence
Disorder																																								?
Disorder confidence