Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP77129
DateThu Jan 5 12:25:34 GMT 2012
Unique Job ID70b8c149cd3188fb

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3clqC_
Top template information
PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a conserved protein of unknown function from2 enterococcus faecalis v583
Confidence and coverage
Confidence:100.0% Coverage: 99%
414 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLHAGPPMRWQEMTGPMKG
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   .........70.........80.........90.........100.........110.........120
Sequence  ACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMGGITSASMPMLVVENVTDG
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   .........130.........140.........150.........160.........170.........180
Sequence  NRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLSAALGRMERGIDLTAMMAQGI
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   .........190.........200.........210.........220.........230.........240
Sequence  TMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEVMDFLSVTDQFFLNLAMAYCKAA
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   .........250.........260.........270.........280.........290.........300
Sequence  MDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFTAPVNTPQGLFFTGFSQEQANPDMG
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   .........310.........320.........330.........340.........350.........360
Sequence  DSAITETFGIGGAAMIAAPGVTRFVGAGGMEAARAVSEEMAEIYLERNMQLQIPSWDFQG
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   .........370.........380.........390.........400.........410.........
Sequence  ACLGLDIRRVVETGITPLINTGIAHKEAGIGQIGAGTVRAPLACFEQALEALAESMGIG
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3clq chain C

3D model

Region: 1 - 416
Aligned: 414
Modelled: 415
Confidence: 100.0%
Identity: 43%
PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a conserved protein of unknown function from2 enterococcus faecalis v583

Phyre2

PDB 2pw4 chain A domain 1

3D model

Region: 76 - 137
Aligned: 49
Modelled: 62
Confidence: 62.1%
Identity: 18%
Fold: Jann2411-like
Superfamily: Jann2411-like
Family: Jann2411-like

Phyre2

PDB 2cqj chain A

3D model

Region: 66 - 89
Aligned: 24
Modelled: 24
Confidence: 49.5%
Identity: 33%
PDB header:rna binding protein
Chain: A: PDB Molecule:u3 small nucleolar ribonucleoprotein protein
PDBTitle: solution structure of the s4 domain of u3 small nucleolar2 ribonucleoprotein protein imp3 homolog

Phyre2

PDB 2htm chain B

3D model

Region: 352 - 419
Aligned: 55
Modelled: 68
Confidence: 45.8%
Identity: 22%
PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8

Phyre2

PDB 1pdz chain A domain 2

3D model

Region: 197 - 248
Aligned: 51
Modelled: 52
Confidence: 45.3%
Identity: 24%
Fold: Enolase N-terminal domain-like
Superfamily: Enolase N-terminal domain-like
Family: Enolase N-terminal domain-like

Phyre2

PDB 2akz chain A domain 2

3D model

Region: 197 - 245
Aligned: 49
Modelled: 49
Confidence: 38.2%
Identity: 18%
Fold: Enolase N-terminal domain-like
Superfamily: Enolase N-terminal domain-like
Family: Enolase N-terminal domain-like

Phyre2

PDB 2al1 chain A domain 2

3D model

Region: 197 - 245
Aligned: 49
Modelled: 49
Confidence: 33.9%
Identity: 24%
Fold: Enolase N-terminal domain-like
Superfamily: Enolase N-terminal domain-like
Family: Enolase N-terminal domain-like

Phyre2

PDB 1alu chain A

3D model

Region: 142 - 199
Aligned: 53
Modelled: 53
Confidence: 33.0%
Identity: 15%
Fold: 4-helical cytokines
Superfamily: 4-helical cytokines
Family: Long-chain cytokines

Phyre2

PDB 2re2 chain A

3D model

Region: 74 - 96
Aligned: 22
Modelled: 23
Confidence: 32.2%
Identity: 27%
PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized protein ta1041;
PDBTitle: crystal structure of a putative iron-molybdenum cofactor (femo-co)2 dinitrogenase (ta1041m) from thermoplasma acidophilum dsm 1728 at3 1.30 a resolution

Phyre2

PDB 1h3f chain A domain 2

3D model

Region: 62 - 89
Aligned: 28
Modelled: 28
Confidence: 21.6%
Identity: 11%
Fold: Alpha-L RNA-binding motif
Superfamily: Alpha-L RNA-binding motif
Family: Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain

Phyre2

PDB 2y9x chain G

3D model

Region: 257 - 299
Aligned: 43
Modelled: 43
Confidence: 21.2%
Identity: 30%
PDB header:oxidoreductase
Chain: G: PDB Molecule:lectin-like fold protein;
PDBTitle: crystal structure of ppo3, a tyrosinase from agaricus bisporus, in2 deoxy-form that contains additional unknown lectin-like subunit,3 with inhibitor tropolone

Phyre2

PDB 1c06 chain A

3D model

Region: 65 - 89
Aligned: 25
Modelled: 25
Confidence: 21.1%
Identity: 20%
Fold: Alpha-L RNA-binding motif
Superfamily: Alpha-L RNA-binding motif
Family: Ribosomal protein S4

Phyre2

PDB 3hp7 chain A

3D model

Region: 65 - 88
Aligned: 24
Modelled: 18
Confidence: 19.4%
Identity: 21%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hemolysin, putative;
PDBTitle: putative hemolysin from streptococcus thermophilus.

Phyre2

PDB 1vjt chain A

3D model

Region: 306 - 381
Aligned: 57
Modelled: 75
Confidence: 18.3%
Identity: 7%
PDB header:hydrolase
Chain: A: PDB Molecule:alpha-glucosidase;
PDBTitle: crystal structure of alpha-glucosidase (tm0752) from thermotoga2 maritima at 2.50 a resolution

Phyre2

PDB 2d5n chain B

3D model

Region: 87 - 121
Aligned: 35
Modelled: 35
Confidence: 17.7%
Identity: 26%
PDB header:hydrolase, oxidoreductase
Chain: B: PDB Molecule:riboflavin biosynthesis protein ribd;
PDBTitle: crystal structure of a bifunctional deaminase and reductase2 involved in riboflavin biosynthesis

Phyre2

PDB 2l58 chain A

3D model

Region: 176 - 190
Aligned: 15
Modelled: 15
Confidence: 16.7%
Identity: 47%
PDB header:apoptosis
Chain: A: PDB Molecule:activator of apoptosis harakiri;
PDBTitle: solution structure of the cytosolic fragment 22-53 of bcl-2 member2 harakiri

Phyre2

PDB 2gy9 chain D domain 1

3D model

Region: 65 - 89
Aligned: 25
Modelled: 25
Confidence: 16.4%
Identity: 12%
Fold: Alpha-L RNA-binding motif
Superfamily: Alpha-L RNA-binding motif
Family: Ribosomal protein S4

Phyre2

PDB 2isb chain A domain 1

3D model

Region: 17 - 47
Aligned: 31
Modelled: 31
Confidence: 15.3%
Identity: 16%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: FumA C-terminal domain-like
Family: FumA C-terminal domain-like

Phyre2

PDB 3msu chain A

3D model

Region: 346 - 375
Aligned: 30
Modelled: 30
Confidence: 13.8%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:citrate synthase;
PDBTitle: crystal structure of citrate synthase from francisella tularensis

Phyre2

PDB 1nub chain A domain 2

3D model

Region: 90 - 97
Aligned: 8
Modelled: 8
Confidence: 12.4%
Identity: 25%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: EGF/Laminin
Family: Follistatin (FS) module N-terminal domain, FS-N

Phyre2
1

c3clqC_
2

d2pw4a1
3

c2cqjA_
4

c2htmB_
5

d1pdza2
6

d2akza2
7

d2al1a2
8

d1alua_
9

c2re2A_
10

d1h3fa2
11

c2y9xG_
12

d1c06a_
13

c3hp7A_
14

c1vjtA_
15

c2d5nB_
16

c2l58A_
17

d2gy9d1
18

d2isba1
19

c3msuA_
20

d1nuba2
21



22



23



24



25



26



27



28



29



30



31



32



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34



35



36



37



38



39



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41



42



43



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56






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3clqC_



100.0 43 PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a conserved protein of unknown function from2 enterococcus faecalis v583
2d2pw4a1



62.1 18 Fold:Jann2411-like
Superfamily:Jann2411-like
Family:Jann2411-like
3c2cqjA_



49.5 33 PDB header:rna binding protein
Chain: A: PDB Molecule:u3 small nucleolar ribonucleoprotein protein
PDBTitle: solution structure of the s4 domain of u3 small nucleolar2 ribonucleoprotein protein imp3 homolog
4c2htmB_



45.8 22 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
5d1pdza2



45.3 24 Fold:Enolase N-terminal domain-like
Superfamily:Enolase N-terminal domain-like
Family:Enolase N-terminal domain-like
6d2akza2



38.2 18 Fold:Enolase N-terminal domain-like
Superfamily:Enolase N-terminal domain-like
Family:Enolase N-terminal domain-like
7d2al1a2



33.9 24 Fold:Enolase N-terminal domain-like
Superfamily:Enolase N-terminal domain-like
Family:Enolase N-terminal domain-like
8d1alua_



33.0 15 Fold:4-helical cytokines
Superfamily:4-helical cytokines
Family:Long-chain cytokines
9c2re2A_



32.2 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized protein ta1041;
PDBTitle: crystal structure of a putative iron-molybdenum cofactor (femo-co)2 dinitrogenase (ta1041m) from thermoplasma acidophilum dsm 1728 at3 1.30 a resolution
10d1h3fa2



21.6 11 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain
11c2y9xG_



21.2 30 PDB header:oxidoreductase
Chain: G: PDB Molecule:lectin-like fold protein;
PDBTitle: crystal structure of ppo3, a tyrosinase from agaricus bisporus, in2 deoxy-form that contains additional unknown lectin-like subunit,3 with inhibitor tropolone
12d1c06a_



21.1 20 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:Ribosomal protein S4
13c3hp7A_



19.4 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hemolysin, putative;
PDBTitle: putative hemolysin from streptococcus thermophilus.
14c1vjtA_



18.3 7 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-glucosidase;
PDBTitle: crystal structure of alpha-glucosidase (tm0752) from thermotoga2 maritima at 2.50 a resolution
15c2d5nB_



17.7 26 PDB header:hydrolase, oxidoreductase
Chain: B: PDB Molecule:riboflavin biosynthesis protein ribd;
PDBTitle: crystal structure of a bifunctional deaminase and reductase2 involved in riboflavin biosynthesis
16c2l58A_



16.7 47 PDB header:apoptosis
Chain: A: PDB Molecule:activator of apoptosis harakiri;
PDBTitle: solution structure of the cytosolic fragment 22-53 of bcl-2 member2 harakiri
17d2gy9d1



16.4 12 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:Ribosomal protein S4
18d2isba1



15.3 16 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:FumA C-terminal domain-like
Family:FumA C-terminal domain-like
19c3msuA_



13.8 20 PDB header:transferase
Chain: A: PDB Molecule:citrate synthase;
PDBTitle: crystal structure of citrate synthase from francisella tularensis
20d1nuba2



12.4 25 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:EGF/Laminin
Family:Follistatin (FS) module N-terminal domain, FS-N
21d2fyma2



not modelled 12.2 18 Fold:Enolase N-terminal domain-like
Superfamily:Enolase N-terminal domain-like
Family:Enolase N-terminal domain-like
22c2ldkA_



not modelled 12.2 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution nmr structure of protein aaur_3427 from arthrobacter2 aurescens, northeast structural genomics consortium target aar96
23c2qnfB_



not modelled 11.7 28 PDB header:hydrolase/dna
Chain: B: PDB Molecule:recombination endonuclease vii;
PDBTitle: crystal structure of t4 endonuclease vii h43n mutant in2 complex with heteroduplex dna containing base mismatches
24c2xzmD_



not modelled 11.5 9 PDB header:ribosome
Chain: D: PDB Molecule:ribosomal protein s4 containing protein;
PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1
25c3d0jA_



not modelled 11.4 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein ca_c3497;
PDBTitle: crystal structure of conserved protein of unknown function ca_c34972 from clostridium acetobutylicum atcc 824
26c2bibA_



not modelled 11.1 12 PDB header:hydrolase
Chain: A: PDB Molecule:teichoic acid phosphorylcholine esterase/ choline binding
PDBTitle: crystal structure of the complete modular teichioic acid2 phosphorylcholine esterase pce (cbpe) from streptococcus3 pneumoniae
27d1jh3a_



not modelled 10.4 18 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain
28d1kfia4



not modelled 9.9 29 Fold:TBP-like
Superfamily:Phosphoglucomutase, C-terminal domain
Family:Phosphoglucomutase, C-terminal domain
29d1duvg1



not modelled 9.7 19 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
30d1t6la2



not modelled 9.5 67 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
31d2o34a1



not modelled 9.4 43 Fold:T-fold
Superfamily:ApbE-like
Family:DVU1097-like
32d2jeka1



not modelled 9.4 17 Fold:Rv1873-like
Superfamily:Rv1873-like
Family:Rv1873-like
33c2bs5A_



not modelled 9.2 20 PDB header:sugar binding protein
Chain: A: PDB Molecule:fucose-binding lectin protein;
PDBTitle: lectin from ralstonia solanacearum complexed with 2-2 fucosyllactose
34c2hxvA_



not modelled 8.9 29 PDB header:biosynthetic protein
Chain: A: PDB Molecule:diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5-
PDBTitle: crystal structure of a diaminohydroxyphosphoribosylaminopyrimidine2 deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase (tm1828)3 from thermotoga maritima at 1.80 a resolution
35d1s4da_



not modelled 8.7 19 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
36d1p9ka_



not modelled 8.3 38 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:YbcJ-like
37d3pmga4



not modelled 8.0 19 Fold:TBP-like
Superfamily:Phosphoglucomutase, C-terminal domain
Family:Phosphoglucomutase, C-terminal domain
38c2i7uA_



not modelled 7.6 48 PDB header:de novo protein/ligand binding protein
Chain: A: PDB Molecule:four-alpha-helix bundle;
PDBTitle: structural and dynamical analysis of a four-alpha-helix2 bundle with designed anesthetic binding pockets
39c1zc1A_



not modelled 7.4 20 PDB header:protein turnover
Chain: A: PDB Molecule:ubiquitin fusion degradation protein 1;
PDBTitle: ufd1 exhibits the aaa-atpase fold with two distinct2 ubiquitin interaction sites
40d2uubd1



not modelled 7.3 25 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:Ribosomal protein S4
41d2hsja1



not modelled 7.1 19 Fold:Flavodoxin-like
Superfamily:SGNH hydrolase
Family:Acetylhydrolase
42c1s1hD_



not modelled 7.0 23 PDB header:ribosome
Chain: D: PDB Molecule:40s ribosomal protein s9-a;
PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1h,4 contains 40s subunit. the 60s ribosomal subunit is in file5 1s1i.
43c2yujA_



not modelled 6.9 20 PDB header:protein binding
Chain: A: PDB Molecule:ubiquitin fusion degradation 1-like;
PDBTitle: solution structure of human ubiquitin fusion degradation2 protein 1 homolog ufd1
44d1twda_



not modelled 6.6 17 Fold:TIM beta/alpha-barrel
Superfamily:CutC-like
Family:CutC-like
45c3bbnD_



not modelled 6.3 15 PDB header:ribosome
Chain: D: PDB Molecule:ribosomal protein s4;
PDBTitle: homology model for the spinach chloroplast 30s subunit2 fitted to 9.4a cryo-em map of the 70s chlororibosome.
46c2iunD_



not modelled 6.3 25 PDB header:viral protein
Chain: D: PDB Molecule:avian adenovirus celo long fibre;
PDBTitle: structure of the c-terminal head domain of the avian2 adenovirus celo long fibre (p21 crystal form)
47d1dxha1



not modelled 6.1 19 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
48c2zt9F_



not modelled 6.0 37 PDB header:photosynthesis
Chain: F: PDB Molecule:cytochrome b6-f complex subunit 7;
PDBTitle: crystal structure of the cytochrome b6f complex from nostoc sp. pcc2 7120
49c2e0wA_



not modelled 6.0 14 PDB header:transferase
Chain: A: PDB Molecule:gamma-glutamyltranspeptidase;
PDBTitle: t391a precursor mutant protein of gamma-glutamyltranspeptidase from2 escherichia coli
50c3l2eB_



not modelled 5.9 16 PDB header:transferase
Chain: B: PDB Molecule:glycocyamine kinase beta chain;
PDBTitle: glycocyamine kinase, alpha-beta heterodimer from marine worm2 namalycastis sp.
51c2lf2A_



not modelled 5.7 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution nmr structure of the ahsa1-like protein chu_1110 from2 cytophaga hutchinsonii, northeast structural genomics consortium3 target chr152
52c2w40C_



not modelled 5.7 18 PDB header:transferase
Chain: C: PDB Molecule:glycerol kinase, putative;
PDBTitle: crystal structure of plasmodium falciparum glycerol kinase2 with bound glycerol
53c2f6sA_



not modelled 5.6 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:cell filamentation protein, putative;
PDBTitle: structure of cell filamentation protein (fic) from helicobacter pylori
54c3btpA_



not modelled 5.5 36 PDB header:dna binding protein, chaperone
Chain: A: PDB Molecule:single-strand dna-binding protein;
PDBTitle: crystal structure of agrobacterium tumefaciens vire2 in complex with2 its chaperone vire1: a novel fold and implications for dna binding
55d2c42a2



not modelled 5.3 44 Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:PFOR PP module
56c1yzxB_



not modelled 5.2 45 PDB header:transferase
Chain: B: PDB Molecule:glutathione s-transferase kappa 1;
PDBTitle: crystal structure of human kappa class glutathione2 transferase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0