Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP31224
DateThu Jan 5 11:47:22 GMT 2012
Unique Job ID6b373747e88d0410

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1oy8A_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
Confidence and coverage
Confidence:100.0% Coverage: 96%
1006 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT
Secondary structure 
SS confidence 
Disorder  ??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ
Secondary structure 
SS confidence 
Disorder 
?????
????
????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS
Secondary structure 
SS confidence 
Disorder 
?
???
?????
?
??
?
???
?
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL
Secondary structure 
SS confidence 
Disorder 
?
????????????????????
?
??
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL
Secondary structure 
SS confidence 
Disorder 
?
???
???
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL
Secondary structure 
SS confidence 
Disorder 
???
?
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR
Secondary structure 
SS confidence 
Disorder 
?????????????
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT
Secondary structure 
SS confidence 
Disorder 
???
??
?
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD
Secondary structure 
SS confidence 
Disorder 
????????????
????
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG
Secondary structure 
SS confidence 
Disorder  ?
???????????????
?
??????
?????
Disorder confidence 
 
   .........730.........740.........750.........760.........770.........780
Sequence  LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR
Secondary structure 
SS confidence 
Disorder  ??
?
?
?
Disorder confidence 
 
   .........790.........800.........810.........820.........830.........840
Sequence  MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA
Secondary structure 
SS confidence 
Disorder  ??
?
?
?
??
?
??????
???
??????
Disorder confidence 
 
   .........850.........860.........870.........880.........890.........900
Sequence  MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........910.........920.........930.........940.........950.........960
Sequence  VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL
Secondary structure 
SS confidence 
Disorder 
?
???
Disorder confidence 
 
   .........970.........980.........990.........1000.........1010.........1020
Sequence  IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........1030.........1040.........
Sequence  FVPVFFVVVRRRFSRKNEDIEHSHTVDHH
Secondary structure 
SS confidence 
Disorder 
??????????????????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1oy8 chain A

3D model

Region: 7 - 1036
Aligned: 1006
Modelled: 1016
Confidence: 100.0%
Identity: 100%
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump

Phyre2

PDB 3k07 chain A

3D model

Region: 1 - 1030
Aligned: 999
Modelled: 1009
Confidence: 100.0%
Identity: 20%
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa

Phyre2

PDB 3aqp chain B

3D model

Region: 86 - 1032
Aligned: 675
Modelled: 715
Confidence: 100.0%
Identity: 18%
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus

Phyre2

PDB 1iwg chain A domain 8

3D model

Region: 837 - 1036
Aligned: 200
Modelled: 200
Confidence: 100.0%
Identity: 87%
Fold: Multidrug efflux transporter AcrB transmembrane domain
Superfamily: Multidrug efflux transporter AcrB transmembrane domain
Family: Multidrug efflux transporter AcrB transmembrane domain

Phyre2

PDB 1iwg chain A domain 7

3D model

Region: 304 - 498
Aligned: 195
Modelled: 195
Confidence: 100.0%
Identity: 89%
Fold: Multidrug efflux transporter AcrB transmembrane domain
Superfamily: Multidrug efflux transporter AcrB transmembrane domain
Family: Multidrug efflux transporter AcrB transmembrane domain

Phyre2

PDB 1iwg chain A domain 1

3D model

Region: 38 - 134
Aligned: 97
Modelled: 97
Confidence: 99.9%
Identity: 100%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 1iwg chain A domain 2

3D model

Region: 232 - 330
Aligned: 98
Modelled: 99
Confidence: 99.7%
Identity: 63%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 1iwg chain A domain 5

3D model

Region: 182 - 273
Aligned: 92
Modelled: 92
Confidence: 99.7%
Identity: 100%
Fold: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains

Phyre2

PDB 1iwg chain A domain 6

3D model

Region: 725 - 812
Aligned: 88
Modelled: 88
Confidence: 99.3%
Identity: 100%
Fold: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains

Phyre2

PDB 1iwg chain A domain 3

3D model

Region: 567 - 673
Aligned: 107
Modelled: 107
Confidence: 99.1%
Identity: 100%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 1iwg chain A domain 4

3D model

Region: 674 - 859
Aligned: 97
Modelled: 98
Confidence: 98.0%
Identity: 100%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 2rop chain A

3D model

Region: 62 - 209
Aligned: 119
Modelled: 135
Confidence: 95.4%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of domains 3 and 4 of human atp7b

Phyre2

PDB 2ew9 chain A

3D model

Region: 62 - 213
Aligned: 125
Modelled: 141
Confidence: 93.2%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of apowln5-6

Phyre2

PDB 1s6u chain A

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 90.6%
Identity: 17%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 2aw0 chain A

3D model

Region: 159 - 213
Aligned: 50
Modelled: 55
Confidence: 89.8%
Identity: 18%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 1cpz chain A

3D model

Region: 159 - 210
Aligned: 47
Modelled: 52
Confidence: 89.5%
Identity: 21%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 1q8l chain A

3D model

Region: 160 - 213
Aligned: 49
Modelled: 54
Confidence: 89.2%
Identity: 14%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 2qif chain A domain 1

3D model

Region: 159 - 215
Aligned: 52
Modelled: 57
Confidence: 88.9%
Identity: 19%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 3dxs chain X

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 87.9%
Identity: 20%
PDB header:hydrolase
Chain: X: PDB Molecule:copper-transporting atpase ran1;
PDBTitle: crystal structure of a copper binding domain from hma7, a p-2 type atpase

Phyre2

PDB 1yjr chain A

3D model

Region: 159 - 213
Aligned: 50
Modelled: 50
Confidence: 87.5%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the apo form of the sixth soluble2 domain a69p mutant of menkes protein

Phyre2
1
c1oy8A_
2
c3k07A_
3
c3aqpB_
4
d1iwga8
5
d1iwga7
6
d1iwga1
7
d1iwga2
8
d1iwga5
9
d1iwga6
10
d1iwga3
11
d1iwga4
12
c2ropA_
13
c2ew9A_
14
d1s6ua_
15
d2aw0a_
16
d1cpza_
17
d1q8la_
18
d2qifa1
19
c3dxsX_
20
c1yjrA_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1oy8A_
100.0 100 PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
2c3k07A_
100.0 20 PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
3c3aqpB_
100.0 18 PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
4d1iwga8
100.0 87 Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
5d1iwga7
100.0 89 Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
6d1iwga1
99.9 100 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
7d1iwga2
99.7 63 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
8d1iwga5
99.7 100 Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
9d1iwga6
99.3 100 Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
10d1iwga3
99.1 100 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
11d1iwga4
98.0 100 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
12c2ropA_
95.4 13 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of domains 3 and 4 of human atp7b
13c2ew9A_
93.2 18 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of apowln5-6
14d1s6ua_
90.6 17 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
15d2aw0a_
89.8 18 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
16d1cpza_
89.5 21 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
17d1q8la_
89.2 14 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
18d2qifa1
88.9 19 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
19c3dxsX_
87.9 20 PDB header:hydrolase
Chain: X: PDB Molecule:copper-transporting atpase ran1;
PDBTitle: crystal structure of a copper binding domain from hma7, a p-2 type atpase
20c1yjrA_
87.5 14 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the apo form of the sixth soluble2 domain a69p mutant of menkes protein
21c2l3mA_
not modelled 87.3 14 PDB header:metal binding protein
Chain: A: PDB Molecule:copper-ion-binding protein;
PDBTitle: solution structure of the putative copper-ion-binding protein from2 bacillus anthracis str. ames
22d1kvja_
not modelled 86.6 22 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
23d1p6ta1
not modelled 86.4 20 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
24c2ga7A_
not modelled 86.3 20 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the copper(i) form of the third metal-2 binding domain of atp7a protein (menkes disease protein)
25d1osda_
not modelled 85.6 16 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
26c2ldiA_
not modelled 85.4 17 PDB header:hydrolase
Chain: A: PDB Molecule:zinc-transporting atpase;
PDBTitle: nmr solution structure of ziaan sub mutant
27c2yvxD_
not modelled 85.4 12 PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
28d1p6ta2
not modelled 85.0 17 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
29c2kt2A_
not modelled 84.6 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:mercuric reductase;
PDBTitle: structure of nmera, the n-terminal hma domain of tn501 mercuric2 reductase
30c1yg0A_
not modelled 83.9 9 PDB header:metal transport
Chain: A: PDB Molecule:cop associated protein;
PDBTitle: solution structure of apo-copp from helicobacter pylori
31c2kkhA_
not modelled 83.9 9 PDB header:metal transport
Chain: A: PDB Molecule:putative heavy metal transporter;
PDBTitle: structure of the zinc binding domain of the atpase hma4
32c1y3kA_
not modelled 80.5 16 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the apo form of the fifth domain of2 menkes protein
33d1afia_
not modelled 79.4 14 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
34c2rmlA_
not modelled 78.8 16 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting p-type atpase copa;
PDBTitle: solution structure of the n-terminal soluble domains of2 bacillus subtilis copa
35c2ofhX_
not modelled 76.3 15 PDB header:hydrolase, membrane protein
Chain: X: PDB Molecule:zinc-transporting atpase;
PDBTitle: solution structure of the n-terminal domain of the zinc(ii) atpase2 ziaa in its apo form
36d1qupa2
not modelled 75.8 12 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
37c1jk9D_
not modelled 70.5 13 PDB header:oxidoreductase
Chain: D: PDB Molecule:copper chaperone for superoxide dismutase;
PDBTitle: heterodimer between h48f-ysod1 and yccs
38c2k2pA_
not modelled 70.0 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein atu1203;
PDBTitle: solution nmr structure of protein atu1203 from agrobacterium2 tumefaciens. northeast structural genomics consortium (nesg) target3 att10, ontario center for structural proteomics target atc1183
39d1mwza_
not modelled 69.6 18 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
40d2ggpb1
not modelled 68.7 13 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
41d1sb6a_
not modelled 68.0 19 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
42c2gcfA_
not modelled 67.5 17 PDB header:hydrolase
Chain: A: PDB Molecule:cation-transporting atpase pacs;
PDBTitle: solution structure of the n-terminal domain of the coppper(i) atpase2 pacs in its apo form
43c2rogA_
not modelled 61.9 13 PDB header:metal binding protein
Chain: A: PDB Molecule:heavy metal binding protein;
PDBTitle: solution structure of thermus thermophilus hb8 ttha17182 protein in living e. coli cells
44c2crlA_
not modelled 58.9 15 PDB header:chaperone
Chain: A: PDB Molecule:copper chaperone for superoxide dismutase;
PDBTitle: the apo form of hma domain of copper chaperone for2 superoxide dismutase
45c2aj1A_
not modelled 58.3 13 PDB header:hydrolase
Chain: A: PDB Molecule:probable cadmium-transporting atpase;
PDBTitle: solution structure of apocada
46c1qupA_
not modelled 55.4 11 PDB header:chaperone
Chain: A: PDB Molecule:superoxide dismutase 1 copper chaperone;
PDBTitle: crystal structure of the copper chaperone for superoxide2 dismutase
47d1cc8a_
not modelled 53.1 12 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
48d2vv5a2
not modelled 52.6 15 Fold:Ferredoxin-like
Superfamily:Mechanosensitive channel protein MscS (YggB), C-terminal domain
Family:Mechanosensitive channel protein MscS (YggB), C-terminal domain
49c3j09A_
not modelled 47.2 15 PDB header:hydrolase, metal transport
Chain: A: PDB Molecule:copper-exporting p-type atpase a;
PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa
50d2yvxa3
not modelled 41.7 13 Fold:MgtE membrane domain-like
Superfamily:MgtE membrane domain-like
Family:MgtE membrane domain-like
51c2kyzA_
not modelled 37.2 12 PDB header:metal binding protein
Chain: A: PDB Molecule:heavy metal binding protein;
PDBTitle: nmr structure of heavy metal binding protein tm0320 from thermotoga2 maritima
52d2nwwa1
not modelled 34.0 8 Fold:Proton glutamate symport protein
Superfamily:Proton glutamate symport protein
Family:Proton glutamate symport protein
53c1yj7A_
not modelled 33.0 15 PDB header:protein transport
Chain: A: PDB Molecule:escj;
PDBTitle: crystal structure of enteropathogenic e.coli (epec) type iii secretion2 system protein escj
54d2cu6a1
not modelled 24.5 23 Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:PaaD-like
55c3c6fD_
not modelled 20.5 3 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:yetf protein;
PDBTitle: crystal structure of protein bsu07140 from bacillus subtilis
56c2kncA_
not modelled 18.3 2 PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
57d1pw4a_
not modelled 17.8 9 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:Glycerol-3-phosphate transporter
58d1uwda_
not modelled 17.5 18 Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:PaaD-like
59c2yy3B_
not modelled 16.7 9 PDB header:translation
Chain: B: PDB Molecule:elongation factor 1-beta;
PDBTitle: crystal structure of translation elongation factor ef-1 beta from2 pyrococcus horikoshii
60c1ciiA_
not modelled 16.4 17 PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
61d1ek8a_
not modelled 15.0 21 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:Ribosome recycling factor, RRF
Family:Ribosome recycling factor, RRF
62c2jnvA_
not modelled 13.0 12 PDB header:metal transport
Chain: A: PDB Molecule:nifu-like protein 1, chloroplast;
PDBTitle: solution structure of c-terminal domain of nifu-like2 protein from oryza sativa
63c3fryB_
not modelled 12.1 18 PDB header:hydrolase
Chain: B: PDB Molecule:probable copper-exporting p-type atpase a;
PDBTitle: crystal structure of the copa c-terminal metal binding domain
64d1qmga1
not modelled 11.7 25 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
65d1jb0i_
not modelled 10.5 19 Fold:Single transmembrane helix
Superfamily:Subunit VIII of photosystem I reaction centre, PsaI
Family:Subunit VIII of photosystem I reaction centre, PsaI
66c1a87A_
not modelled 10.3 13 PDB header:bacteriocin
Chain: A: PDB Molecule:colicin n;
PDBTitle: colicin n
67d1a87a_
not modelled 10.3 13 Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
68d1dd5a_
not modelled 10.2 16 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:Ribosome recycling factor, RRF
Family:Ribosome recycling factor, RRF
69d2cfxa2
not modelled 10.2 7 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
70c2i88A_
not modelled 10.1 6 PDB header:membrane protein
Chain: A: PDB Molecule:colicin-e1;
PDBTitle: crystal structure of the channel-forming domain of colicin2 e1
71d1is1a_
not modelled 10.0 16 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:Ribosome recycling factor, RRF
Family:Ribosome recycling factor, RRF
72d1fe0a_
not modelled 9.7 13 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
73d1wqga1
not modelled 9.2 15 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:Ribosome recycling factor, RRF
Family:Ribosome recycling factor, RRF
74c3qlbA_
not modelled 9.0 12 PDB header:metal transport
Chain: A: PDB Molecule:enantio-pyochelin receptor;
PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin
75c3g7sA_
not modelled 9.0 18 PDB header:ligase
Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1);
PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus
76c2hdiA_
not modelled 9.0 33 PDB header:protein transport,antimicrobial protein
Chain: A: PDB Molecule:colicin i receptor;
PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.
77d2b3ya2
not modelled 8.9 43 Fold:Aconitase iron-sulfur domain
Superfamily:Aconitase iron-sulfur domain
Family:Aconitase iron-sulfur domain
78d2cg4a2
not modelled 8.8 7 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
79d1nwaa_
not modelled 8.7 24 Fold:Ferredoxin-like
Superfamily:Peptide methionine sulfoxide reductase
Family:Peptide methionine sulfoxide reductase
80c1nwaA_
not modelled 8.7 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:peptide methionine sulfoxide reductase msra;
PDBTitle: structure of mycobacterium tuberculosis methionine2 sulfoxide reductase a in complex with protein-bound3 methionine
81c2i8bB_
not modelled 8.6 22 PDB header:viral protein
Chain: B: PDB Molecule:minor nucleoprotein vp30;
PDBTitle: crystal structure of the c-terminal domain of ebola virus vp30
82d1eh1a_
not modelled 8.4 15 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:Ribosome recycling factor, RRF
Family:Ribosome recycling factor, RRF
83c2yg8B_
not modelled 8.4 14 PDB header:hydrolase
Chain: B: PDB Molecule:dna-3-methyladenine glycosidase ii, putative;
PDBTitle: structure of an unusual 3-methyladenine dna glycosylase ii (2 alka) from deinococcus radiodurans
84d2phcb2
not modelled 8.3 19 Fold:DCoH-like
Superfamily:PH0987 N-terminal domain-like
Family:PH0987 N-terminal domain-like
85d1lr0a_
not modelled 7.9 13 Fold:TolA/TonB C-terminal domain
Superfamily:TolA/TonB C-terminal domain
Family:TolA
86d2cyya2
not modelled 7.9 2 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
87d1bvsa2
not modelled 7.8 15 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:DNA helicase RuvA subunit, middle domain
88c3bdeA_
not modelled 7.8 3 PDB header:unknown function
Chain: A: PDB Molecule:mll5499 protein;
PDBTitle: crystal structure of a dabb family protein with a ferredoxin-like fold2 (mll5499) from mesorhizobium loti maff303099 at 1.79 a resolution
89d1s7ba_
not modelled 7.7 18 Fold:Multidrug resistance efflux transporter EmrE
Superfamily:Multidrug resistance efflux transporter EmrE
Family:Multidrug resistance efflux transporter EmrE
90d1h3da2
not modelled 7.6 19 Fold:Ferredoxin-like
Superfamily:GlnB-like
Family:ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain
91c3lkxB_
not modelled 7.6 19 PDB header:chaperone
Chain: B: PDB Molecule:nascent polypeptide-associated complex subunit alpha;
PDBTitle: human nac dimerization domain
92c3lnoA_
not modelled 7.5 12 PDB header:unknown function
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of domain of unknown function duf59 from2 bacillus anthracis
93c2h5xA_
not modelled 7.5 19 PDB header:dna binding protein
Chain: A: PDB Molecule:holliday junction atp-dependent dna helicase ruva;
PDBTitle: ruva from mycobacterium tuberculosis
94c1d8lA_
not modelled 7.5 19 PDB header:gene regulation
Chain: A: PDB Molecule:protein (holliday junction dna helicase ruva);
PDBTitle: e. coli holliday junction binding protein ruva nh2 region2 lacking domain iii
95c2k9pA_
not modelled 7.4 19 PDB header:membrane protein
Chain: A: PDB Molecule:pheromone alpha factor receptor;
PDBTitle: structure of tm1_tm2 in lppg micelles
96d1wiha_
not modelled 7.4 15 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:Ribosome recycling factor, RRF
Family:Ribosome recycling factor, RRF
97c3ibwA_
not modelled 7.4 24 PDB header:transferase
Chain: A: PDB Molecule:gtp pyrophosphokinase;
PDBTitle: crystal structure of the act domain from gtp2 pyrophosphokinase of chlorobium tepidum. northeast3 structural genomics consortium target ctr148a
98c2ki0A_
not modelled 7.4 6 PDB header:de novo protein
Chain: A: PDB Molecule:ds119;
PDBTitle: nmr structure of a de novo designed beta alpha beta
99d1ydxa2
not modelled 7.3 11 Fold:DNA methylase specificity domain
Superfamily:DNA methylase specificity domain
Family:Type I restriction modification DNA specificity domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0