Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	K	L	I	E	L	R	R	A	K	R	L	A	L	S	L	L	L	I	A	A	A	T	F	V	V	T	L	F	L	P	P	N	F	W	V	S	G	V	K	A	I	A	E	A	A	M	V	G	A	L	A	D	W	F	A	V	V	A
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	F	R	R	V	P	I	P	I	I	S	R	H	T	A	I	I	P	R	N	K	D	R	I	G	E	N	L	G	Q	F	V	Q	E	K	F	L	D	T	Q	S	L	V	A	L	I	R	R	H	E	P	A	L	L	I	G	N	W	F	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	P	E	N	A	R	R	V	G	Q	H	L	L	Q	I	M	S	G	F	L	E	L	T	D	D	A	R	I	Q	R	L	L	K	R	A	V	H	R	A	I	D	K	V	D	L	S	G	T	S	A	L	M	L	E	S	M	T	K	N	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	H	Q	V	L	L	D	T	L	I	A	Q	L	I	A	L	L	Q	R	D	K	S	R	K	F	I	A	Q	Q	I	V	R	W	L	E	S	E	H	P	L	K	A	K	I	L	P	T	E	W	L	G	E	H	S	A	E	L	V	S	D
Secondary structure
SS confidence
Disorder																																								?	?	?	?	?	?		?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	V	N	S	L	L	D	D	I	S	R	D	R	A	H	Q	I	R	H	A	F	D	R	A	T	F	A	L	I	D	K	L	K	N	D	P	E	M	A	A	R	A	D	A	V	K	S	Y	L	K	E	D	E	A	F	N	R	Y	L	S
Secondary structure
SS confidence
Disorder														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		E	L	W	G	D	L	R	E	W	L	K	V	D	I	N	S	E	D	S	R	V	K	E	R	I	A	R	A	G	Q	W	F	G	E	T	L	I	A	D	D	A	L	R	A	S	L	N	G	H	L	E	Q	A	A	H	R	V	A	P	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		F	S	A	F	L	T	R	H	I	S	D	T	V	K	S	W	D	A	R	D	M	S	R	Q	I	E	L	N	I	G	K	D	L	Q	F	I	R	V	N	G	T	L	V	G	G	C	I	G	L	I	L	Y	L	L	S	Q	L	P	A	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.
Sequence		F	P	L	G	N	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1xg7 chain A Region: 53 - 72 Aligned: 20 Modelled: 20 Confidence: 48.1% Identity: 30% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: AgoG-like Phyre2 PDB 1ee8 chain A domain 1 Region: 49 - 94 Aligned: 42 Modelled: 46 Confidence: 44.6% Identity: 21% Fold: S13-like H2TH domain Superfamily: S13-like H2TH domain Family: Middle domain of MutM-like DNA repair proteins Phyre2 PDB 1k3x chain A domain 1 Region: 51 - 94 Aligned: 40 Modelled: 44 Confidence: 42.5% Identity: 13% Fold: S13-like H2TH domain Superfamily: S13-like H2TH domain Family: Middle domain of MutM-like DNA repair proteins Phyre2 PDB 1tdz chain A domain 1 Region: 49 - 94 Aligned: 42 Modelled: 46 Confidence: 37.5% Identity: 17% Fold: S13-like H2TH domain Superfamily: S13-like H2TH domain Family: Middle domain of MutM-like DNA repair proteins Phyre2 PDB 1r2z chain A domain 1 Region: 48 - 94 Aligned: 43 Modelled: 47 Confidence: 37.5% Identity: 19% Fold: S13-like H2TH domain Superfamily: S13-like H2TH domain Family: Middle domain of MutM-like DNA repair proteins Phyre2 PDB 3edy chain A Region: 71 - 120 Aligned: 50 Modelled: 50 Confidence: 36.5% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:tripeptidyl-peptidase 1; PDBTitle: crystal structure of the precursor form of human tripeptidyl-peptidase2 1 Phyre2 PDB 1k82 chain A domain 1 Region: 51 - 94 Aligned: 40 Modelled: 44 Confidence: 35.3% Identity: 10% Fold: S13-like H2TH domain Superfamily: S13-like H2TH domain Family: Middle domain of MutM-like DNA repair proteins Phyre2 PDB 1xqo chain A Region: 53 - 72 Aligned: 20 Modelled: 20 Confidence: 30.6% Identity: 30% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: AgoG-like Phyre2 PDB 2knc chain A Region: 402 - 426 Aligned: 25 Modelled: 25 Confidence: 29.9% Identity: 28% PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex Phyre2 PDB 3ee6 chain A Region: 70 - 120 Aligned: 51 Modelled: 51 Confidence: 29.7% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:tripeptidyl-peptidase 1; PDBTitle: crystal structure analysis of tripeptidyl peptidase -i Phyre2 PDB 1ug3 chain A domain 1 Region: 78 - 208 Aligned: 106 Modelled: 108 Confidence: 29.0% Identity: 15% Fold: alpha-alpha superhelix Superfamily: ARM repeat Family: MIF4G domain-like Phyre2 PDB 2lbg chain A Region: 400 - 412 Aligned: 13 Modelled: 13 Confidence: 27.8% Identity: 46% PDB header:membrane protein Chain: A: PDB Molecule:major prion protein; PDBTitle: structure of the chr of the prion protein in dpc micelles Phyre2 PDB 1t1e chain A domain 2 Region: 70 - 120 Aligned: 50 Modelled: 51 Confidence: 25.9% Identity: 12% Fold: Ferredoxin-like Superfamily: Protease propeptides/inhibitors Family: Subtilase propeptides/inhibitors Phyre2 PDB 2k1a chain A Region: 402 - 426 Aligned: 25 Modelled: 25 Confidence: 25.9% Identity: 28% PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: bicelle-embedded integrin alpha(iib) transmembrane segment Phyre2 PDB 3h2z chain A Region: 333 - 406 Aligned: 74 Modelled: 74 Confidence: 25.4% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase; PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri Phyre2 PDB 1t5j chain A Region: 399 - 421 Aligned: 22 Modelled: 23 Confidence: 24.6% Identity: 18% Fold: ADP-ribosylglycohydrolase Superfamily: ADP-ribosylglycohydrolase Family: ADP-ribosylglycohydrolase Phyre2 PDB 3g9d chain B Region: 399 - 421 Aligned: 22 Modelled: 23 Confidence: 24.3% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:dinitrogenase reductase activacting PDBTitle: crystal structure glycohydrolase Phyre2 PDB 2aq0 chain A domain 1 Region: 71 - 122 Aligned: 50 Modelled: 50 Confidence: 23.6% Identity: 8% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Hef domain-like Phyre2 PDB 2qty chain B Region: 399 - 421 Aligned: 22 Modelled: 23 Confidence: 22.1% Identity: 27% PDB header:hydrolase Chain: B: PDB Molecule:poly(adp-ribose) glycohydrolase arh3; PDBTitle: crystal structure of mouse adp-ribosylhydrolase 3 (marh3) Phyre2 PDB 2r6c chain G Region: 260 - 390 Aligned: 131 Modelled: 128 Confidence: 21.6% Identity: 15% PDB header:replication Chain: G: PDB Molecule:dnag primase, helicase binding domain; PDBTitle: crystal form bh2 Phyre2 1 d1xg7a_ 2 d1ee8a1 3 d1k3xa1 4 d1tdza1 5 d1r2za1 6 c3edyA_ 7 d1k82a1 8 d1xqoa_ 9 c2kncA_ 10 c3ee6A_ 11 d1ug3a1 12 c2lbgA_ 13 d1t1ea2 14 c2k1aA_ 15 c3h2zA_ 16 d1t5ja_ 17 c3g9dB_ 18 d2aq0a1 19 c2qtyB_ 20 c2r6cG_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1xg7a_ 48.1 30 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:AgoG-like 2 d1ee8a1 44.6 21 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Middle domain of MutM-like DNA repair proteins 3 d1k3xa1 42.5 13 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Middle domain of MutM-like DNA repair proteins 4 d1tdza1 37.5 17 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Middle domain of MutM-like DNA repair proteins 5 d1r2za1 37.5 19 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Middle domain of MutM-like DNA repair proteins 6 c3edyA_ 36.5 22 PDB header:hydrolase Chain: A: PDB Molecule:tripeptidyl-peptidase 1; PDBTitle: crystal structure of the precursor form of human tripeptidyl-peptidase2 1 7 d1k82a1 35.3 10 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Middle domain of MutM-like DNA repair proteins 8 d1xqoa_ 30.6 30 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:AgoG-like 9 c2kncA_ 29.9 28 PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 10 c3ee6A_ 29.7 22 PDB header:hydrolase Chain: A: PDB Molecule:tripeptidyl-peptidase 1; PDBTitle: crystal structure analysis of tripeptidyl peptidase -i 11 d1ug3a1 29.0 15 Fold:alpha-alpha superhelix Superfamily:ARM repeat Family:MIF4G domain-like 12 c2lbgA_ 27.8 46 PDB header:membrane protein Chain: A: PDB Molecule:major prion protein; PDBTitle: structure of the chr of the prion protein in dpc micelles 13 d1t1ea2 25.9 12 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Subtilase propeptides/inhibitors 14 c2k1aA_ 25.9 28 PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: bicelle-embedded integrin alpha(iib) transmembrane segment 15 c3h2zA_ 25.4 18 PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase; PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri 16 d1t5ja_ 24.6 18 Fold:ADP-ribosylglycohydrolase Superfamily:ADP-ribosylglycohydrolase Family:ADP-ribosylglycohydrolase 17 c3g9dB_ 24.3 23 PDB header:hydrolase Chain: B: PDB Molecule:dinitrogenase reductase activacting PDBTitle: crystal structure glycohydrolase 18 d2aq0a1 23.6 8 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 19 c2qtyB_ 22.1 27 PDB header:hydrolase Chain: B: PDB Molecule:poly(adp-ribose) glycohydrolase arh3; PDBTitle: crystal structure of mouse adp-ribosylhydrolase 3 (marh3) 20 c2r6cG_ 21.6 15 PDB header:replication Chain: G: PDB Molecule:dnag primase, helicase binding domain; PDBTitle: crystal form bh2 21 c2k7rA_ not modelled 20.3 16 PDB header:replication Chain: A: PDB Molecule:primosomal protein dnai; PDBTitle: n-terminal domain of the bacillus subtilis helicase-loading2 protein dnai 22 c2wocA_ not modelled 19.4 27 PDB header:hydrolase Chain: A: PDB Molecule:adp-ribosyl-[dinitrogen reductase] glycohydrolase; PDBTitle: crystal structure of the dinitrogenase reductase-activating2 glycohydrolase (drag) from rhodospirillum rubrum 23 c2yzwA_ not modelled 19.2 27 PDB header:hydrolase Chain: A: PDB Molecule:adp-ribosylglycohydrolase; PDBTitle: adp-ribosylglycohydrolase-related protein complex 24 c1b9uA_ not modelled 17.8 28 PDB header:hydrolase Chain: A: PDB Molecule:protein (atp synthase); PDBTitle: membrane domain of the subunit b of the e.coli atp synthase 25 d2gp4a2 not modelled 16.9 13 Fold:IlvD/EDD N-terminal domain-like Superfamily:IlvD/EDD N-terminal domain-like Family:lvD/EDD N-terminal domain-like 26 d1rh5b_ not modelled 16.8 22 Fold:Single transmembrane helix Superfamily:Preprotein translocase SecE subunit Family:Preprotein translocase SecE subunit 27 c1ug3A_ not modelled 15.7 15 PDB header:translation Chain: A: PDB Molecule:eukaryotic protein synthesis initiation factor PDBTitle: c-terminal portion of human eif4gi 28 d2piha1 not modelled 15.0 5 Fold:YheA-like Superfamily:YheA/YmcA-like Family:YmcA-like 29 c2pihA_ not modelled 15.0 5 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein ymca; PDBTitle: crystal structure of protein ymca from bacillus subtilis,2 northeast structural genomics target sr375 30 c2kncB_ not modelled 14.8 14 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 31 c2f5qA_ not modelled 14.6 19 PDB header:hydrolase/dna Chain: A: PDB Molecule:formamidopyrimidine-dna glycosidase; PDBTitle: catalytically inactive (e3q) mutm crosslinked to oxog:c2 containing dna cc2 32 c3hd7A_ not modelled 13.9 6 PDB header:exocytosis Chain: A: PDB Molecule:vesicle-associated membrane protein 2; PDBTitle: helical extension of the neuronal snare complex into the membrane,2 spacegroup c 1 2 1 33 d1v54d_ not modelled 13.9 13 Fold:Single transmembrane helix Superfamily:Mitochondrial cytochrome c oxidase subunit IV Family:Mitochondrial cytochrome c oxidase subunit IV 34 c3qnqD_ not modelled 13.8 16 PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system 35 c2y69Q_ not modelled 13.7 13 PDB header:electron transport Chain: Q: PDB Molecule:cytochrome c oxidase subunit 4 isoform 1; PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular2 oxygen 36 d2a1ja1 not modelled 13.6 8 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 37 d2crga1 not modelled 13.2 29 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Myb/SANT domain 38 c2kluA_ not modelled 12.8 26 PDB header:immune system, membrane protein Chain: A: PDB Molecule:t-cell surface glycoprotein cd4; PDBTitle: nmr structure of the transmembrane and cytoplasmic domains2 of human cd4 39 c2w2eA_ not modelled 12.7 10 PDB header:membrane protein Chain: A: PDB Molecule:aquaporin; PDBTitle: 1.15 angstrom crystal structure of p.pastoris aquaporin,2 aqy1, in a closed conformation at ph 3.5 40 d1xi8a3 not modelled 12.5 20 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like 41 c3hfwA_ not modelled 12.4 20 PDB header:hydrolase Chain: A: PDB Molecule:protein adp-ribosylarginine hydrolase; PDBTitle: crystal structure of human adp-ribosylhydrolase 1 (harh1) 42 c2opfA_ not modelled 12.2 15 PDB header:hydrolase/dna Chain: A: PDB Molecule:endonuclease viii; PDBTitle: crystal structure of the dna repair enzyme endonuclease-viii (nei)2 from e. coli (r252a) in complex with ap-site containing dna substrate 43 c2gp4A_ not modelled 12.0 15 PDB header:lyase Chain: A: PDB Molecule:6-phosphogluconate dehydratase; PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis 44 c3a46B_ not modelled 11.3 13 PDB header:hydrolase Chain: B: PDB Molecule:formamidopyrimidine-dna glycosylase; PDBTitle: crystal structure of mvnei1/thf complex 45 c2l23A_ not modelled 11.0 13 PDB header:transcription Chain: A: PDB Molecule:mediator of rna polymerase ii transcription subunit 25; PDBTitle: nmr structure of the acid (activator interacting domain) of the human2 mediator med25 protein 46 c1wazA_ not modelled 11.0 18 PDB header:transport protein Chain: A: PDB Molecule:merf; PDBTitle: nmr structure determination of the bacterial mercury2 transporter, merf, in micelles 47 c3h3pT_ not modelled 10.8 43 PDB header:immune system Chain: T: PDB Molecule:4e10_s0_1tjlc_004_n; PDBTitle: crystal structure of hiv epitope-scaffold 4e10 fv complex 48 c1q90L_ not modelled 10.7 30 PDB header:photosynthesis Chain: L: PDB Molecule:cytochrome b6f complex subunit petl; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii 49 d1q90l_ not modelled 10.7 30 Fold:Single transmembrane helix Superfamily:PetL subunit of the cytochrome b6f complex Family:PetL subunit of the cytochrome b6f complex 50 c3kvhA_ not modelled 10.7 17 PDB header:rna binding protein Chain: A: PDB Molecule:protein syndesmos; PDBTitle: crystal structure of human protein syndesmos (nudt16-like protein) 51 c1ee8A_ not modelled 10.7 21 PDB header:dna binding protein Chain: A: PDB Molecule:mutm (fpg) protein; PDBTitle: crystal structure of mutm (fpg) protein from thermus thermophilus hb8 52 c1nnjA_ not modelled 10.2 15 PDB header:hydrolase Chain: A: PDB Molecule:formamidopyrimidine-dna glycosylase; PDBTitle: crystal structure complex between the lactococcus lactis fpg and an2 abasic site containing dna 53 d1ymga1 not modelled 10.1 28 Fold:Aquaporin-like Superfamily:Aquaporin-like Family:Aquaporin-like 54 c1ymgA_ not modelled 10.1 28 PDB header:membrane protein Chain: A: PDB Molecule:lens fiber major intrinsic protein; PDBTitle: the channel architecture of aquaporin o at 2.2 angstrom resolution 55 c2hjmB_ not modelled 9.8 21 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein pf1176; PDBTitle: crystal structure of a singleton protein pf1176 from p. furiosus 56 d1k6za_ not modelled 9.7 26 Fold:Secretion chaperone-like Superfamily:Type III secretory system chaperone-like Family:Type III secretory system chaperone 57 c2vt2A_ not modelled 9.5 15 PDB header:transcription Chain: A: PDB Molecule:redox-sensing transcriptional repressor rex; PDBTitle: structure and functional properties of the bacillus2 subtilis transcriptional repressor rex 58 c3d9sB_ not modelled 9.4 33 PDB header:membrane protein Chain: B: PDB Molecule:aquaporin-5; PDBTitle: human aquaporin 5 (aqp5) - high resolution x-ray structure 59 d1rfza_ not modelled 9.4 11 Fold:YutG-like Superfamily:YutG-like Family:YutG-like 60 c2zu6E_ not modelled 9.4 13 PDB header:hydrolase Chain: E: PDB Molecule:programmed cell death protein 4; PDBTitle: crystal structure of the eif4a-pdcd4 complex 61 c1k82D_ not modelled 9.3 10 PDB header:hydrolase/dna Chain: D: PDB Molecule:formamidopyrimidine-dna glycosylase; PDBTitle: crystal structure of e.coli formamidopyrimidine-dna2 glycosylase (fpg) covalently trapped with dna 62 c2kqzA_ not modelled 9.3 4 PDB header:protein binding Chain: A: PDB Molecule:proteasomal ubiquitin receptor adrm1; PDBTitle: fragment of proteasome protein 63 d1xova2 not modelled 9.1 13 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:N-acetylmuramoyl-L-alanine amidase-like 64 d1jlja_ not modelled 9.1 18 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 65 c2qtqB_ not modelled 9.0 9 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator, tetr family; PDBTitle: crystal structure of a predicted dna-binding transcriptional regulator2 (saro_1072) from novosphingobium aromaticivorans dsm at 1.85 a3 resolution 66 c3c02A_ not modelled 8.9 17 PDB header:membrane protein Chain: A: PDB Molecule:aquaglyceroporin; PDBTitle: x-ray structure of the aquaglyceroporin from plasmodium falciparum 67 d1ug8a_ not modelled 8.8 22 Fold:IF3-like Superfamily:R3H domain Family:R3H domain 68 c2bcxB_ not modelled 8.8 86 PDB header:calcium binding protein Chain: B: PDB Molecule:ryanodine receptor 1; PDBTitle: crystal structure of calmodulin in complex with a ryanodine2 receptor peptide 69 d1jyaa_ not modelled 8.6 26 Fold:Secretion chaperone-like Superfamily:Type III secretory system chaperone-like Family:Type III secretory system chaperone 70 d2a4ha1 not modelled 8.6 20 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Selenoprotein W-related 71 c2zmeA_ not modelled 8.5 5 PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex 72 c3cuqA_ not modelled 8.3 5 PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex 73 d2cdxa_ not modelled 8.3 20 Fold:Snake toxin-like Superfamily:Snake toxin-like Family:Snake venom toxins 74 d1rc2a_ not modelled 8.3 33 Fold:Aquaporin-like Superfamily:Aquaporin-like Family:Aquaporin-like 75 d1y0na_ not modelled 8.2 11 Fold:YehU-like Superfamily:YehU-like Family:YehU-like 76 c1u0bB_ not modelled 8.2 13 PDB header:ligase/rna Chain: B: PDB Molecule:cysteinyl trna; PDBTitle: crystal structure of cysteinyl-trna synthetase binary2 complex with trnacys 77 d1dd4c_ not modelled 8.2 18 Fold:Ribosomal protein L7/12, oligomerisation (N-terminal) domain Superfamily:Ribosomal protein L7/12, oligomerisation (N-terminal) domain Family:Ribosomal protein L7/12, oligomerisation (N-terminal) domain 78 c1amlA_ not modelled 8.1 27 PDB header:serine protease inhibitor Chain: A: PDB Molecule:amyloid a4; PDBTitle: the alzheimer`s disease amyloid a4 peptide (residues 1-40) 79 d1j4na_ not modelled 8.1 22 Fold:Aquaporin-like Superfamily:Aquaporin-like Family:Aquaporin-like 80 d1cksa_ not modelled 8.1 67 Fold:Cell cycle regulatory proteins Superfamily:Cell cycle regulatory proteins Family:Cell cycle regulatory proteins 81 c2dzrA_ not modelled 8.1 29 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i repeat domain- PDBTitle: solution structure of rsgi ruh-067, a gtf2i domain in human2 cdna 82 c1dvpA_ not modelled 8.0 8 PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine PDBTitle: crystal structure of the vhs and fyve tandem domains of hrs,2 a protein involved in membrane trafficking and signal3 transduction 83 c2jesG_ not modelled 8.0 20 PDB header:viral protein Chain: G: PDB Molecule:portal protein; PDBTitle: portal protein from bacteriophage spp1 84 d1u5ta1 not modelled 8.0 16 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Vacuolar sorting protein domain 85 d2hxja1 not modelled 7.9 22 Fold:FinO-like Superfamily:FinO-like Family:FinO-like 86 c2f2bA_ not modelled 7.9 33 PDB header:membrane protein Chain: A: PDB Molecule:aquaporin aqpm; PDBTitle: crystal structure of integral membrane protein aquaporin aqpm at 1.68a2 resolution 87 c3ahhA_ not modelled 7.8 12 PDB header:lyase Chain: A: PDB Molecule:xylulose 5-phosphate/fructose 6-phosphate phosphoketolase; PDBTitle: h142a mutant of phosphoketolase from bifidobacterium breve complexed2 with acetyl thiamine diphosphate 88 c1m5iA_ not modelled 7.8 13 PDB header:antitumor protein Chain: A: PDB Molecule:apc protein; PDBTitle: crystal structure of the coiled coil region 129-250 of the2 tumor suppressor gene product apc 89 d1hq1a_ not modelled 7.7 35 Fold:Signal peptide-binding domain Superfamily:Signal peptide-binding domain Family:Signal peptide-binding domain 90 c2yqkA_ not modelled 7.7 26 PDB header:transcription/apoptosis Chain: A: PDB Molecule:arginine-glutamic acid dipeptide repeats protein; PDBTitle: solution structure of the sant domain in arginine-glutamic2 acid dipeptide (re) repeats 91 c1zaxZ_ not modelled 7.7 18 PDB header:structural protein Chain: Z: PDB Molecule:50s ribosomal protein l7/l12; PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p212121,2 form b 92 c1zawV_ not modelled 7.7 18 PDB header:structural protein Chain: V: PDB Molecule:50s ribosomal protein l7/l12; PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p212121,2 form a 93 d1rkta2 not modelled 7.6 12 Fold:Tetracyclin repressor-like, C-terminal domain Superfamily:Tetracyclin repressor-like, C-terminal domain Family:Tetracyclin repressor-like, C-terminal domain 94 c1dfwA_ not modelled 7.6 54 PDB header:immune system Chain: A: PDB Molecule:lung surfactant protein b; PDBTitle: conformational mapping of the n-terminal segment of2 surfactant protein b in lipid using 13c-enhanced fourier3 transform infrared spectroscopy (ftir) 95 d1qb2a_ not modelled 7.6 18 Fold:Signal peptide-binding domain Superfamily:Signal peptide-binding domain Family:Signal peptide-binding domain 96 d1sb0a_ not modelled 7.6 14 Fold:Kix domain of CBP (creb binding protein) Superfamily:Kix domain of CBP (creb binding protein) Family:Kix domain of CBP (creb binding protein) 97 c3llqB_ not modelled 7.5 25 PDB header:membrane protein Chain: B: PDB Molecule:aquaporin z 2; PDBTitle: aquaporin structure from plant pathogen agrobacterium tumerfaciens 98 c2krxA_ not modelled 7.5 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:asl3597 protein; PDBTitle: solution nmr structure of asl3597 from nostoc sp. pcc7120. northeast2 structural genomics consortium target id nsr244. 99 c1jauA_ not modelled 7.5 33 PDB header:viral protein Chain: A: PDB Molecule:transmembrane glycoprotein (gp41); PDBTitle: nmr solution structure of the trp-rich peptide of hiv gp412 bound to dpc micelles

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0