PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3d9sB_

Fold library id	PDB Header	Molecule	Title
c3d9sB_	PDB header: membrane protein	Chain: B: PDB Molecule: aquaporin-5;	PDBTitle: human aquaporin 5 (aqp5) - high resolution x-ray structure

Links to external resources
Added to library: Tue Mar 16 14:10:24 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S K K E V C S V A F L K A V F A E F L A T L I F V F F G L G S A L K W P S A L P T I L Q I A L A F G L A I G T L A Q A L G P V S G G H I N P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T S
T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A I T L A L L V G N Q I S L L R A F F Y V A A Q L V G A I A G A G I L Y G V A P L N A R G N L A V N A L N N N T T Q G Q A M V V E L I L T F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
S
T T T T
T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence Q L A L C I F A S T D S R R T S P V G S P A L S I G L S V T L G H L V G I Y F T G C S M N P A R S F G P A V V M N R F S P A H W V F W V G P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S
S
S
S S T T
T T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . .

Sequence I V G A V L A A I L Y F Y L L F P N S L S L S E R V A I I K G T Y E P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S
T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	K	K	E	V	C	S	V	A	F	L	K	A	V	F	A	E	F	L	A	T	L	I	F	V	F	F	G	L	G	S	A	L	K	W	P	S	A	L	P	T	I	L	Q	I	A	L	A	F	G	L	A	I	G	T	L	A	Q	A	L	G	P	V	S	G	G	H	I	N	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S																								T	T	S			T	T	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	I	T	L	A	L	L	V	G	N	Q	I	S	L	L	R	A	F	F	Y	V	A	A	Q	L	V	G	A	I	A	G	A	G	I	L	Y	G	V	A	P	L	N	A	R	G	N	L	A	V	N	A	L	N	N	N	T	T	Q	G	Q	A	M	V	V	E	L	I	L	T	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T		S																											S						T	T	T	T						T	T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	Q	L	A	L	C	I	F	A	S	T	D	S	R	R	T	S	P	V	G	S	P	A	L	S	I	G	L	S	V	T	L	G	H	L	V	G	I	Y	F	T	G	C	S	M	N	P	A	R	S	F	G	P	A	V	V	M	N	R	F	S	P	A	H	W	V	F	W	V	G	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T		S	S			S																									S			S	S											T	T				T	T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.
Sequence	I	V	G	A	V	L	A	A	I	L	Y	F	Y	L	L	F	P	N	S	L	S	L	S	E	R	V	A	I	I	K	G	T	Y	E	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T	T	S															T