Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP06715
DateThu Jan 5 10:59:22 GMT 2012
Unique Job ID5c3dd332c7a98b9d

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1geuA_
Top template information
PDB header:oxidoreductase(flavoenzyme)
Chain: A: PDB Molecule:glutathione reductase;
PDBTitle: anatomy of an engineered nad-binding site
Confidence and coverage
Confidence:100.0% Coverage:100%
448 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVNVGCVPKKVMWHAAQIR
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Disorder  ???
























































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   .........70.........80.........90.........100.........110.........120
Sequence  EAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENVLGKNNVDVIKGFARFVDA
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?
















































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   .........130.........140.........150.........160.........170.........180
Sequence  KTLEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGFFALPALPERVAVVGAGYIAV
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   .........190.........200.........210.........220.........230.........240
Sequence  ELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVMNAEGPQLHTNAIPKAVVKNTDG
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   .........250.........260.........270.........280.........290.........300
Sequence  SLTLELEDGRSETVDCLIWAIGREPANDNINLEAAGVKTNEKGYIVVDKYQNTNIEGIYA
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   .........310.........320.........330.........340.........350.........360
Sequence  VGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHLDYSNIPTVVFSHPPIGTVGLTEPQAR
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   .........370.........380.........390.........400.........410.........420
Sequence  EQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMKLVCVGSEEKIVGIHGIGFGMDEMLQGFA
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   .........430.........440.........450
Sequence  VALKMGATKKDFDNTVAIHPTAAEEFVTMR
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Disorder 























??????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1geu chain A

3D model

Region: 3 - 450
Aligned: 448
Modelled: 448
Confidence: 100.0%
Identity: 98%
PDB header:oxidoreductase(flavoenzyme)
Chain: A: PDB Molecule:glutathione reductase;
PDBTitle: anatomy of an engineered nad-binding site

Phyre2

PDB 2r9z chain B

3D model

Region: 2 - 449
Aligned: 445
Modelled: 448
Confidence: 100.0%
Identity: 52%
PDB header:oxidoreductase
Chain: B: PDB Molecule:glutathione amide reductase;
PDBTitle: glutathione amide reductase from chromatium gracile

Phyre2

PDB 1bwc chain A

3D model

Region: 1 - 450
Aligned: 448
Modelled: 450
Confidence: 100.0%
Identity: 54%
PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (glutathione reductase);
PDBTitle: structure of human glutathione reductase complexed with ajoene2 inhibitor and subversive substrate

Phyre2

PDB 1tyt chain A

3D model

Region: 1 - 450
Aligned: 447
Modelled: 450
Confidence: 100.0%
Identity: 36%
PDB header:oxidoreductase
Chain: A: PDB Molecule:trypanothione reductase, oxidized form;
PDBTitle: crystal and molecular structure of crithidia fasciculata2 trypanothione reductase at 2.6 angstroms resolution

Phyre2

PDB 2v6o chain A

3D model

Region: 2 - 449
Aligned: 446
Modelled: 448
Confidence: 100.0%
Identity: 40%
PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin glutathione reductase;
PDBTitle: structure of schistosoma mansoni thioredoxin-glutathione2 reductase (smtgr)

Phyre2

PDB 2hqm chain B

3D model

Region: 3 - 450
Aligned: 447
Modelled: 448
Confidence: 100.0%
Identity: 51%
PDB header:oxidoreductase
Chain: B: PDB Molecule:glutathione reductase;
PDBTitle: crystal structure of glutathione reductase glr1 from the yeast2 saccharomyces cerevisiae

Phyre2

PDB 3o0h chain A

3D model

Region: 2 - 449
Aligned: 440
Modelled: 448
Confidence: 100.0%
Identity: 36%
PDB header:oxidoreductase
Chain: A: PDB Molecule:glutathione reductase;
PDBTitle: crystal structure of glutathione reductase from bartonella henselae

Phyre2

PDB 2w0h chain A

3D model

Region: 2 - 450
Aligned: 446
Modelled: 449
Confidence: 100.0%
Identity: 35%
PDB header:oxidoreductase
Chain: A: PDB Molecule:trypanothione reductase;
PDBTitle: x ray structure of leishmania infantum trypanothione2 reductase in complex with antimony and nadph

Phyre2

PDB 2eq8 chain E

3D model

Region: 1 - 449
Aligned: 441
Modelled: 449
Confidence: 100.0%
Identity: 31%
PDB header:oxidoreductase
Chain: E: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide
PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdp

Phyre2

PDB 1ebd chain B

3D model

Region: 4 - 448
Aligned: 440
Modelled: 445
Confidence: 100.0%
Identity: 30%
PDB header:complex (oxidoreductase/transferase)
Chain: B: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: dihydrolipoamide dehydrogenase complexed with the binding2 domain of the dihydrolipoamide acetylase

Phyre2

PDB 1v59 chain B

3D model

Region: 1 - 448
Aligned: 444
Modelled: 448
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: crystal structure of yeast lipoamide dehydrogenase2 complexed with nad+

Phyre2

PDB 1dxl chain C

3D model

Region: 2 - 448
Aligned: 443
Modelled: 447
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: C: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: dihydrolipoamide dehydrogenase of glycine decarboxylase2 from pisum sativum

Phyre2

PDB 1nda chain D

3D model

Region: 5 - 450
Aligned: 442
Modelled: 446
Confidence: 100.0%
Identity: 36%
PDB header:oxidoreductase
Chain: D: PDB Molecule:trypanothione oxidoreductase;
PDBTitle: the structure of trypanosoma cruzi trypanothione reductase2 in the oxidized and nadph reduced state

Phyre2

PDB 2a8x chain A

3D model

Region: 4 - 449
Aligned: 443
Modelled: 446
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure of lipoamide dehydrogenase from2 mycobacterium tuberculosis

Phyre2

PDB 2eq7 chain B

3D model

Region: 5 - 448
Aligned: 437
Modelled: 444
Confidence: 100.0%
Identity: 31%
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxoglutarate dehydrogenase e3 component;
PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdo

Phyre2

PDB 1lvl chain A

3D model

Region: 2 - 448
Aligned: 441
Modelled: 447
Confidence: 100.0%
Identity: 28%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: the refined structure of pseudomonas putida lipoamide dehydrogenase2 complexed with nad+ at 2.45 angstroms resolution

Phyre2

PDB 1ojt chain A

3D model

Region: 2 - 448
Aligned: 442
Modelled: 447
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: A: PDB Molecule:surface protein;
PDBTitle: structure of dihydrolipoamide dehydrogenase

Phyre2

PDB 2c3d chain B

3D model

Region: 2 - 450
Aligned: 446
Modelled: 449
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxopropyl-com reductase;
PDBTitle: 2.15 angstrom crystal structure of 2-ketopropyl coenzyme m2 oxidoreductase carboxylase with a coenzyme m disulfide3 bound at the active site

Phyre2

PDB 3urh chain B

3D model

Region: 5 - 449
Aligned: 441
Modelled: 445
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure of a dihydrolipoamide dehydrogenase from2 sinorhizobium meliloti 1021

Phyre2

PDB 1lpf chain B

3D model

Region: 2 - 448
Aligned: 443
Modelled: 447
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: three-dimensional structure of lipoamide dehydrogenase from2 pseudomonas fluorescens at 2.8 angstroms resolution.3 analysis of redox and thermostability properties

Phyre2
1

c1geuA_
2

c2r9zB_
3

c1bwcA_
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c1tytA_
5

c2v6oA_
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c2hqmB_
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c3o0hA_
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c2w0hA_
9

c2eq8E_
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c1ebdB_
11

c1v59B_
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c1dxlC_
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c1ndaD_
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c2a8xA_
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c2eq7B_
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c1lvlA_
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c1ojtA_
18

c2c3dB_
19

c3urhB_
20

c1lpfB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1geuA_



100.0 98 PDB header:oxidoreductase(flavoenzyme)
Chain: A: PDB Molecule:glutathione reductase;
PDBTitle: anatomy of an engineered nad-binding site
2c2r9zB_



100.0 52 PDB header:oxidoreductase
Chain: B: PDB Molecule:glutathione amide reductase;
PDBTitle: glutathione amide reductase from chromatium gracile
3c1bwcA_



100.0 54 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (glutathione reductase);
PDBTitle: structure of human glutathione reductase complexed with ajoene2 inhibitor and subversive substrate
4c1tytA_



100.0 36 PDB header:oxidoreductase
Chain: A: PDB Molecule:trypanothione reductase, oxidized form;
PDBTitle: crystal and molecular structure of crithidia fasciculata2 trypanothione reductase at 2.6 angstroms resolution
5c2v6oA_



100.0 40 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin glutathione reductase;
PDBTitle: structure of schistosoma mansoni thioredoxin-glutathione2 reductase (smtgr)
6c2hqmB_



100.0 51 PDB header:oxidoreductase
Chain: B: PDB Molecule:glutathione reductase;
PDBTitle: crystal structure of glutathione reductase glr1 from the yeast2 saccharomyces cerevisiae
7c3o0hA_



100.0 36 PDB header:oxidoreductase
Chain: A: PDB Molecule:glutathione reductase;
PDBTitle: crystal structure of glutathione reductase from bartonella henselae
8c2w0hA_



100.0 35 PDB header:oxidoreductase
Chain: A: PDB Molecule:trypanothione reductase;
PDBTitle: x ray structure of leishmania infantum trypanothione2 reductase in complex with antimony and nadph
9c2eq8E_



100.0 31 PDB header:oxidoreductase
Chain: E: PDB Molecule:pyruvate dehydrogenase complex, dihydrolipoamide
PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdp
10c1ebdB_



100.0 30 PDB header:complex (oxidoreductase/transferase)
Chain: B: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: dihydrolipoamide dehydrogenase complexed with the binding2 domain of the dihydrolipoamide acetylase
11c1v59B_



100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: crystal structure of yeast lipoamide dehydrogenase2 complexed with nad+
12c1dxlC_



100.0 27 PDB header:oxidoreductase
Chain: C: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: dihydrolipoamide dehydrogenase of glycine decarboxylase2 from pisum sativum
13c1ndaD_



100.0 36 PDB header:oxidoreductase
Chain: D: PDB Molecule:trypanothione oxidoreductase;
PDBTitle: the structure of trypanosoma cruzi trypanothione reductase2 in the oxidized and nadph reduced state
14c2a8xA_



100.0 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure of lipoamide dehydrogenase from2 mycobacterium tuberculosis
15c2eq7B_



100.0 31 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxoglutarate dehydrogenase e3 component;
PDBTitle: crystal structure of lipoamide dehydrogenase from thermus thermophilus2 hb8 with psbdo
16c1lvlA_



100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: the refined structure of pseudomonas putida lipoamide dehydrogenase2 complexed with nad+ at 2.45 angstroms resolution
17c1ojtA_



100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:surface protein;
PDBTitle: structure of dihydrolipoamide dehydrogenase
18c2c3dB_



100.0 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxopropyl-com reductase;
PDBTitle: 2.15 angstrom crystal structure of 2-ketopropyl coenzyme m2 oxidoreductase carboxylase with a coenzyme m disulfide3 bound at the active site
19c3urhB_



100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure of a dihydrolipoamide dehydrogenase from2 sinorhizobium meliloti 1021
20c1lpfB_



100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: three-dimensional structure of lipoamide dehydrogenase from2 pseudomonas fluorescens at 2.8 angstroms resolution.3 analysis of redox and thermostability properties
21c3ic9D_



not modelled 100.0 21 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydrolipoamide dehydrogenase;
PDBTitle: the structure of dihydrolipoamide dehydrogenase from colwellia2 psychrerythraea 34h.
22c1xdiA_



not modelled 100.0 21 PDB header:unknown function
Chain: A: PDB Molecule:rv3303c-lpda;
PDBTitle: crystal structure of lpda (rv3303c) from mycobacterium tuberculosis
23c1onfA_



not modelled 100.0 45 PDB header:oxidoreductase
Chain: A: PDB Molecule:glutathione reductase;
PDBTitle: crystal structure of plasmodium falciparum glutathione reductase
24c2qaeA_



not modelled 100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure analysis of trypanosoma cruzi lipoamide2 dehydrogenase
25c1zmcG_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: G: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure of human dihydrolipoamide dehydrogenase2 complexed to nad+
26c1zkqA_



not modelled 100.0 36 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase 2, mitochondrial;
PDBTitle: crystal structure of mouse thioredoxin reductase type 2
27c1zx9A_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:mercuric reductase;
PDBTitle: crystal structure of tn501 mera
28c3dgzA_



not modelled 100.0 36 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase 2;
PDBTitle: crystal structure of mouse mitochondrial thioredoxin reductase, c-2 terminal 3-residue truncation
29c2nvkX_



not modelled 100.0 34 PDB header:oxidoreductase
Chain: X: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of thioredoxin reductase from drosophila2 melanogaster
30c2cfyB_



not modelled 100.0 38 PDB header:oxidoreductase
Chain: B: PDB Molecule:thioredoxin reductase 1;
PDBTitle: crystal structure of human thioredoxin reductase 1
31c3l8kB_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:dihydrolipoyl dehydrogenase;
PDBTitle: crystal structure of a dihydrolipoyl dehydrogenase from2 sulfolobus solfataricus
32c3ntaA_



not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:fad-dependent pyridine nucleotide-disulphide
PDBTitle: structure of the shewanella loihica pv-4 nadh-dependent persulfide2 reductase
33c2bcpA_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh oxidase;
PDBTitle: structural analysis of streptococcus pyogenes nadh oxidase:2 c44s nox with azide
34c3icrA_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:coenzyme a-disulfide reductase;
PDBTitle: crystal structure of oxidized bacillus anthracis coadr-rhd
35c2cduB_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:nadph oxidase;
PDBTitle: the crystal structure of water-forming nad(p)h oxidase from2 lactobacillus sanfranciscensis
36c3oc4A_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, pyridine nucleotide-disulfide family;
PDBTitle: crystal structure of a pyridine nucleotide-disulfide family2 oxidoreductase from the enterococcus faecalis v583
37c3cgdB_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:pyridine nucleotide-disulfide oxidoreductase, class i;
PDBTitle: pyridine nucleotide complexes with bacillus anthracis coenzyme a-2 disulfide reductase: a structural analysis of dual nad(p)h3 specificity
38c3kd9B_



not modelled 100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:coenzyme a disulfide reductase;
PDBTitle: crystal structure of pyridine nucleotide disulfide oxidoreductase from2 pyrococcus horikoshii
39c1yqzA_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:coenzyme a disulfide reductase;
PDBTitle: structure of coenzyme a-disulfide reductase from2 staphylococcus aureus refined at 1.54 angstrom resolution
40c1nhqA_



not modelled 100.0 15 PDB header:oxidoreductase (h2o2(a))
Chain: A: PDB Molecule:nadh peroxidase;
PDBTitle: crystallographic analyses of nadh peroxidase cys42ala and cys42ser2 mutants: active site structure, mechanistic implications, and an3 unusual environment of arg303
41c3iwaA_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:fad-dependent pyridine nucleotide-disulphide
PDBTitle: crystal structure of a fad-dependent pyridine nucleotide-disulphide2 oxidoreductase from desulfovibrio vulgaris
42c1gv4A_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:programed cell death protein 8;
PDBTitle: murine apoptosis-inducing factor (aif)
43c3fg2P_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: P: PDB Molecule:putative rubredoxin reductase;
PDBTitle: crystal structure of ferredoxin reductase for the cyp199a2 system from2 rhodopseudomonas palustris
44c3lxdA_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:fad-dependent pyridine nucleotide-disulphide
PDBTitle: crystal structure of ferredoxin reductase arr from novosphingobium2 aromaticivorans
45c1m6iA_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:programmed cell death protein 8;
PDBTitle: crystal structure of apoptosis inducing factor (aif)
46c2gr2A_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:ferredoxin reductase;
PDBTitle: crystal structure of ferredoxin reductase, bpha4 (oxidized form)
47c3kljA_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:nad(fad)-dependent dehydrogenase, nirb-family (n-terminal
PDBTitle: crystal structure of nadh:rubredoxin oxidoreductase from clostridium2 acetobutylicum
48c1q1wA_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:putidaredoxin reductase;
PDBTitle: crystal structure of putidaredoxin reductase from2 pseudomonas putida
49c3ef6A_



not modelled 100.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:toluene 1,2-dioxygenase system ferredoxin--nad(+)
PDBTitle: crystal structure of toluene 2,3-dioxygenase reductase
50c2v3aA_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:rubredoxin reductase;
PDBTitle: crystal structure of rubredoxin reductase from pseudomonas2 aeruginosa.
51c1hyuA_



not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:alkyl hydroperoxide reductase subunit f;
PDBTitle: crystal structure of intact ahpf
52c1xhcA_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh oxidase /nitrite reductase;
PDBTitle: nadh oxidase /nitrite reductase from pyrococcus furiosus pfu-1140779-2 001
53c1gthD_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
54c2zbwA_



not modelled 100.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of thioredoxin reductase-like protein from thermus2 thermophilus hb8
55c3hyxC_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:sulfide-quinone reductase;
PDBTitle: 3-d x-ray structure of the sulfide:quinone oxidoreductase from aquifex2 aeolicus in complex with aurachin c
56c3ctyA_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of t. acidophilum thioredoxin reductase
57c3r9uA_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: thioredoxin-disulfide reductase from campylobacter jejuni.
58d3grsa1



not modelled 100.0 47 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
59c3kpgA_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:sulfide-quinone reductase, putative;
PDBTitle: crystal structure of sulfide:quinone oxidoreductase from2 acidithiobacillus ferrooxidans in complex with decylubiquinone
60c1fl2A_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:alkyl hydroperoxide reductase subunit f;
PDBTitle: catalytic core component of the alkylhydroperoxide reductase ahpf from2 e.coli
61c2q7vA_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of deinococcus radiodurans thioredoxin2 reductase
62c2vdcI_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: I: PDB Molecule:glutamate synthase [nadph] small chain;
PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications.
63c3d1cA_



not modelled 100.0 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:flavin-containing putative monooxygenase;
PDBTitle: crystal structure of flavin-containing putative monooxygenase2 (np_373108.1) from staphylococcus aureus mu50 at 2.40 a resolution
64c1vdcA_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dependent thioredoxin reductase;
PDBTitle: structure of nadph dependent thioredoxin reductase
65c1f6mF_



not modelled 100.0 21 PDB header:oxidoreductase
Chain: F: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of a complex between thioredoxin2 reductase, thioredoxin, and the nadp+ analog, aadp+
66c3lzxB_



not modelled 100.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:ferredoxin--nadp reductase 2;
PDBTitle: crystal structure of ferredoxin-nadp+ oxidoreductase from bacillus2 subtilis (form ii)
67c3fbsB_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase;
PDBTitle: the crystal structure of the oxidoreductase from agrobacterium2 tumefaciens
68c3k30B_



not modelled 100.0 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:histamine dehydrogenase;
PDBTitle: histamine dehydrogenase from nocardiodes simplex
69d3grsa3



not modelled 100.0 70 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
70c1djnB_



not modelled 100.0 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:trimethylamine dehydrogenase;
PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1)
71c3d8xB_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:thioredoxin reductase 1;
PDBTitle: crystal structure of saccharomyces cerevisiae nadph dependent2 thioredoxin reductase 1
72c3f8rD_



not modelled 100.0 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:thioredoxin reductase (trxb-3);
PDBTitle: crystal structure of sulfolobus solfataricus thioredoxin2 reductase b3 in complex with two nadp molecules
73d1gesa3



not modelled 100.0 100 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
74c2q0lA_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: helicobacter pylori thioredoxin reductase reduced by sodium dithionite2 in complex with nadp+
75c1ps9A_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:2,4-dienoyl-coa reductase;
PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase
76d1dxla1



not modelled 100.0 30 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
77c3ab1B_



not modelled 100.0 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:ferredoxin--nadp reductase;
PDBTitle: crystal structure of ferredoxin nadp+ oxidoreductase
78c3h8lA_



not modelled 100.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh oxidase;
PDBTitle: the first x-ray structure of a sulfide:quinone2 oxidoreductase: insights into sulfide oxidation mechanism
79d3lada1



not modelled 100.0 30 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
80d1lpfa1



not modelled 100.0 29 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
81d1v59a1



not modelled 100.0 30 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
82d1ojta1



not modelled 100.0 29 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
83c1fcdB_



not modelled 100.0 15 PDB header:electron transport(flavocytochrome)
Chain: B: PDB Molecule:flavocytochrome c sulfide dehydrogenase (flavin-
PDBTitle: the structure of flavocytochrome c sulfide dehydrogenase2 from a purple phototrophic bacterium chromatium vinosum at3 2.5 angstroms resolution
84d1onfa3



not modelled 100.0 58 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
85d1ebda1



not modelled 100.0 30 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
86c2a87A_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin reductase;
PDBTitle: crystal structure of m. tuberculosis thioredoxin reductase
87c1lqtB_



not modelled 99.9 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:fpra;
PDBTitle: a covalent modification of nadp+ revealed by the atomic resolution2 structure of fpra, a mycobacterium tuberculosis oxidoreductase
88d1feca1



not modelled 99.9 29 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
89d1mo9a1



not modelled 99.9 26 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
90c1cjcA_



not modelled 99.9 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (adrenodoxin reductase);
PDBTitle: structure of adrenodoxin reductase of mitochondrial p4502 systems
91c1y56A_



not modelled 99.9 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein ph1363;
PDBTitle: crystal structure of l-proline dehydrogenase from p.horikoshii
92d1aoga1



not modelled 99.9 24 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
93d1h6va1



not modelled 99.9 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
94d1lvla1



not modelled 99.9 33 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
95d1h6va3



not modelled 99.9 40 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
96d3lada3



not modelled 99.9 27 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
97d1aoga3



not modelled 99.9 39 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
98d1feca3



not modelled 99.9 37 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
99d1lpfa3



not modelled 99.9 28 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
100d1dxla3



not modelled 99.9 28 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
101d1v59a3



not modelled 99.9 37 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
102d1ojta3



not modelled 99.9 24 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
103d1xdia2



not modelled 99.9 17 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
104d1gv4a1



not modelled 99.9 18 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
105c3s5wB_



not modelled 99.9 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-ornithine 5-monooxygenase;
PDBTitle: ornithine hydroxylase (pvda) from pseudomonas aeruginosa
106d1ebda3



not modelled 99.9 33 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
107c1x31A_



not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:sarcosine oxidase alpha subunit;
PDBTitle: crystal structure of heterotetrameric sarcosine oxidase from2 corynebacterium sp. u-96
108d1lvla3



not modelled 99.9 30 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
109d1mo9a3



not modelled 99.9 22 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
110d1m6ia1



not modelled 99.9 21 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
111d1d4ca2



not modelled 99.9 22 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
112c2vq7B_



not modelled 99.9 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:flavin-containing monooxygenase;
PDBTitle: bacterial flavin-containing monooxygenase in complex with2 nadp: native data
113d1y0pa2



not modelled 99.9 24 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
114d2bs2a2



not modelled 99.9 13 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
115d1qo8a2



not modelled 99.9 20 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
116d1nhpa3



not modelled 99.9 12 Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
117c3gwdA_



not modelled 99.9 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:cyclohexanone monooxygenase;
PDBTitle: closed crystal structure of cyclohexanone monooxygenase
118d1kf6a2



not modelled 99.9 17 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
119d2gqfa1



not modelled 99.9 18 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:HI0933 N-terminal domain-like
120c1w4xA_



not modelled 99.8 15 PDB header:oxygenase
Chain: A: PDB Molecule:phenylacetone monooxygenase;
PDBTitle: phenylacetone monooxygenase, a baeyer-villiger2 monooxygenase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0