Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	E	K	M	M	S	Y	Q	P	Q	T	E	A	A	T	S	R	F	L	N	V	E	E	A	G	K	T	L	R	I	H	F	N	D	C	G	Q	G	D	E	T	V	V	L	L	H	G	S	G	P	G	A	T	G	W	A	N	F	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	N	I	D	P	L	V	E	A	G	Y	R	V	I	L	L	D	C	P	G	W	G	K	S	D	S	V	V	N	S	G	S	R	S	D	L	N	A	R	I	L	K	S	V	V	D	Q	L	D	I	A	K	I	H	L	L	G	N	S	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	G	H	S	S	V	A	F	T	L	K	W	P	E	R	V	G	K	L	V	L	M	G	G	G	T	G	G	M	S	L	F	T	P	M	P	T	E	G	I	K	R	L	N	Q	L	Y	R	Q	P	T	I	E	N	L	K	L	M	M	D
Secondary structure
SS confidence
Disorder																												?		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	F	V	F	D	T	S	D	L	T	D	A	L	F	E	A	R	L	N	N	M	L	S	R	R	D	H	L	E	N	F	V	K	S	L	E	A	N	P	K	Q	F	P	D	F	G	P	R	L	A	E	I	K	A	Q	T	L	I	V	W
Secondary structure
SS confidence
Disorder																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.
Sequence		G	R	N	D	R	F	V	P	M	D	A	G	L	R	L	L	S	G	I	A	G	S	E	L	H	I	F	R	D	C	G	H	W	A	Q	W	E	H	A	D	A	F	N	Q	L	V	L	N	F	L	A	R	P
Secondary structure
SS confidence
Disorder																																																			?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1u2e chain A Region: 8 - 293 Aligned: 286 Modelled: 286 Confidence: 100.0% Identity: 100% PDB header:hydrolase Chain: A: PDB Molecule:2-hydroxy-6-ketonona-2,4-dienedioic acid PDBTitle: crystal structure of the c-c bond hydrolase mhpc Phyre2 PDB 2rhw chain A domain 1 Region: 11 - 292 Aligned: 281 Modelled: 281 Confidence: 100.0% Identity: 51% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Carbon-carbon bond hydrolase Phyre2 PDB 1cr6 chain A Region: 12 - 291 Aligned: 273 Modelled: 278 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor Phyre2 PDB 2vf2 chain A Region: 11 - 291 Aligned: 279 Modelled: 281 Confidence: 100.0% Identity: 40% PDB header:hydrolase Chain: A: PDB Molecule:2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate PDBTitle: x-ray crystal structure of hsad from mycobacterium2 tuberculosis Phyre2 PDB 3kda chain B Region: 9 - 292 Aligned: 275 Modelled: 283 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:cftr inhibitory factor (cif); PDBTitle: crystal structure of the cftr inhibitory factor cif with the h269a2 mutation Phyre2 PDB 1uk8 chain A Region: 15 - 292 Aligned: 265 Modelled: 277 Confidence: 100.0% Identity: 32% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Carbon-carbon bond hydrolase Phyre2 PDB 1hkh chain A Region: 19 - 292 Aligned: 270 Modelled: 274 Confidence: 100.0% Identity: 19% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Haloperoxidase Phyre2 PDB 1brt chain A Region: 18 - 292 Aligned: 271 Modelled: 275 Confidence: 100.0% Identity: 18% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Haloperoxidase Phyre2 PDB 1b6g chain A Region: 14 - 292 Aligned: 276 Modelled: 279 Confidence: 100.0% Identity: 20% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Haloalkane dehalogenase Phyre2 PDB 3oos chain A Region: 16 - 290 Aligned: 266 Modelled: 274 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase family protein; PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne Phyre2 PDB 1c4x chain A Region: 16 - 291 Aligned: 275 Modelled: 276 Confidence: 100.0% Identity: 26% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Carbon-carbon bond hydrolase Phyre2 PDB 3u1t chain A Region: 14 - 292 Aligned: 270 Modelled: 278 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:dmma haloalkane dehalogenase; PDBTitle: haloalkane dehalogenase, dmma, of marine microbial origin Phyre2 PDB 1va4 chain A Region: 17 - 292 Aligned: 268 Modelled: 276 Confidence: 100.0% Identity: 22% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Haloperoxidase Phyre2 PDB 1zd3 chain A domain 2 Region: 6 - 292 Aligned: 280 Modelled: 286 Confidence: 100.0% Identity: 18% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Epoxide hydrolase Phyre2 PDB 2vav chain L Region: 27 - 292 Aligned: 266 Modelled: 265 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) Phyre2 PDB 2xt0 chain A Region: 14 - 291 Aligned: 268 Modelled: 278 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:haloalkane dehalogenase; PDBTitle: dehalogenase dppa from plesiocystis pacifica sir-i Phyre2 PDB 1a8s chain A Region: 17 - 291 Aligned: 267 Modelled: 275 Confidence: 100.0% Identity: 20% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Haloperoxidase Phyre2 PDB 1q0r chain A Region: 16 - 292 Aligned: 271 Modelled: 277 Confidence: 100.0% Identity: 18% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Aclacinomycin methylesterase RdmC Phyre2 PDB 1ehy chain A Region: 11 - 291 Aligned: 272 Modelled: 280 Confidence: 100.0% Identity: 18% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Epoxide hydrolase Phyre2 PDB 3kxp chain D Region: 16 - 291 Aligned: 265 Modelled: 276 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: D: PDB Molecule:alpha-(n-acetylaminomethylene)succinic acid PDBTitle: crystal structure of e-2-(acetamidomethylene)succinate2 hydrolase Phyre2 1 c1u2eA_ 2 d2rhwa1 3 c1cr6A_ 4 c2vf2A_ 5 c3kdaB_ 6 d1uk8a_ 7 d1hkha_ 8 d1brta_ 9 d1b6ga_ 10 c3oosA_ 11 d1c4xa_ 12 c3u1tA_ 13 d1va4a_ 14 d1zd3a2 15 c2vavL_ 16 c2xt0A_ 17 d1a8sa_ 18 d1q0ra_ 19 d1ehya_ 20 c3kxpD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1u2eA_ 100.0 100 PDB header:hydrolase Chain: A: PDB Molecule:2-hydroxy-6-ketonona-2,4-dienedioic acid PDBTitle: crystal structure of the c-c bond hydrolase mhpc 2 d2rhwa1 100.0 51 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 3 c1cr6A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor 4 c2vf2A_ 100.0 40 PDB header:hydrolase Chain: A: PDB Molecule:2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate PDBTitle: x-ray crystal structure of hsad from mycobacterium2 tuberculosis 5 c3kdaB_ 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:cftr inhibitory factor (cif); PDBTitle: crystal structure of the cftr inhibitory factor cif with the h269a2 mutation 6 d1uk8a_ 100.0 32 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 7 d1hkha_ 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 8 d1brta_ 100.0 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 9 d1b6ga_ 100.0 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloalkane dehalogenase 10 c3oosA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase family protein; PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne 11 d1c4xa_ 100.0 26 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 12 c3u1tA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:dmma haloalkane dehalogenase; PDBTitle: haloalkane dehalogenase, dmma, of marine microbial origin 13 d1va4a_ 100.0 22 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 14 d1zd3a2 100.0 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 15 c2vavL_ 100.0 18 PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) 16 c2xt0A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:haloalkane dehalogenase; PDBTitle: dehalogenase dppa from plesiocystis pacifica sir-i 17 d1a8sa_ 100.0 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 18 d1q0ra_ 100.0 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Aclacinomycin methylesterase RdmC 19 d1ehya_ 100.0 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 20 c3kxpD_ 100.0 15 PDB header:hydrolase Chain: D: PDB Molecule:alpha-(n-acetylaminomethylene)succinic acid PDBTitle: crystal structure of e-2-(acetamidomethylene)succinate2 hydrolase 21 d1cr6a2 not modelled 100.0 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 22 d1m33a_ not modelled 100.0 23 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Biotin biosynthesis protein BioH 23 c2cjpA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: structure of potato (solanum tuberosum) epoxide hydrolase i2 (steh1) 24 d1a8qa_ not modelled 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 25 d2vata1 not modelled 100.0 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 26 d1j1ia_ not modelled 100.0 24 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 27 c1j1iA_ not modelled 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:meta cleavage compound hydrolase; PDBTitle: crystal structure of a his-tagged serine hydrolase involved2 in the carbazole degradation (carc enzyme) 28 c3p2mA_ not modelled 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:possible hydrolase; PDBTitle: crystal structure of a novel esterase rv0045c from mycobacterium2 tuberculosis 29 c3e3aA_ not modelled 100.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:possible peroxidase bpoc; PDBTitle: the structure of rv0554 from mycobacterium tuberculosis 30 d1azwa_ not modelled 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 31 c2e3jA_ not modelled 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase ephb; PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom 32 c3fobA_ not modelled 100.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:bromoperoxidase; PDBTitle: crystal structure of bromoperoxidase from bacillus anthracis 33 c2r11D_ not modelled 100.0 19 PDB header:hydrolase Chain: D: PDB Molecule:carboxylesterase np; PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution 34 d1bn7a_ not modelled 100.0 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloalkane dehalogenase 35 c3om8A_ not modelled 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:probable hydrolase; PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01 36 d2b61a1 not modelled 100.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 37 c3qyjB_ not modelled 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:alr0039 protein; PDBTitle: crystal structure of alr0039, a putative alpha/beta hydrolase from2 nostoc sp pcc 7120. 38 c3a2nF_ not modelled 100.0 17 PDB header:hydrolase Chain: F: PDB Molecule:haloalkane dehalogenase; PDBTitle: crystal structure of dbja (wild type type ii p21) 39 d1mtza_ not modelled 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 40 c1zoiC_ not modelled 100.0 18 PDB header:hydrolase Chain: C: PDB Molecule:esterase; PDBTitle: crystal structure of a stereoselective esterase from2 pseudomonas putida ifo12996 41 c3i1iA_ not modelled 100.0 17 PDB header:transferase Chain: A: PDB Molecule:homoserine o-acetyltransferase; PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis 42 c2xuaH_ not modelled 100.0 21 PDB header:hydrolase Chain: H: PDB Molecule:3-oxoadipate enol-lactonase; PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400 43 c2qmqA_ not modelled 100.0 13 PDB header:signaling protein Chain: A: PDB Molecule:protein ndrg2; PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution 44 d1mj5a_ not modelled 100.0 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloalkane dehalogenase 45 c3ibtA_ not modelled 100.0 11 PDB header:oxidoreductase Chain: A: PDB Molecule:1h-3-hydroxy-4-oxoquinoline 2,4-dioxygenase; PDBTitle: structure of 1h-3-hydroxy-4-oxoquinoline 2,4-dioxygenase (qdo) 46 c1wprA_ not modelled 100.0 21 PDB header:signaling protein Chain: A: PDB Molecule:sigma factor sigb regulation protein rsbq; PDBTitle: crystal structure of rsbq inhibited by pmsf 47 c2wj4B_ not modelled 100.0 11 PDB header:oxidoreductase Chain: B: PDB Molecule:1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase; PDBTitle: crystal structure of the cofactor-devoid 1-h-3-hydroxy-4-2 oxoquinaldine 2,4-dioxygenase (hod) from arthrobacter3 nitroguajacolicus ru61a anaerobically complexed with its4 natural substrate 1-h-3-hydroxy-4-oxoquinaldine 48 c2qvbA_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:haloalkane dehalogenase 3; PDBTitle: crystal structure of haloalkane dehalogenase rv2579 from mycobacterium2 tuberculosis 49 d2pl5a1 not modelled 100.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 50 d1a88a_ not modelled 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 51 c1y37A_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:fluoroacetate dehalogenase; PDBTitle: structure of fluoroacetate dehalogenase from burkholderia sp. fa1 52 c3v48B_ not modelled 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd; PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli 53 d1wm1a_ not modelled 100.0 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 54 c2xmzA_ not modelled 100.0 19 PDB header:lyase Chain: A: PDB Molecule:hydrolase, alpha/beta hydrolase fold family; PDBTitle: structure of menh from s. aureus 55 c3qvmA_ not modelled 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:olei00960; PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica 56 c2y6vB_ not modelled 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:peroxisomal membrane protein lpx1; PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i) 57 c3r3xA_ not modelled 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:fluoroacetate dehalogenase; PDBTitle: crystal structure of the fluoroacetate dehalogenase rpa1163 -2 asp110asn/bromoacetate 58 c3r0vA_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase fold protein; PDBTitle: the crystal structure of an alpha/beta hydrolase from sphaerobacter2 thermophilus dsm 20745. 59 c3bwxA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase; PDBTitle: crystal structure of an alpha/beta hydrolase (yp_496220.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.50 a resolution 60 c3fsgC_ not modelled 100.0 16 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta superfamily hydrolase; PDBTitle: crystal structure of alpha/beta superfamily hydrolase from oenococcus2 oeni psu-1 61 c3nwoA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:proline iminopeptidase; PDBTitle: crystal structure of proline iminopeptidase mycobacterium smegmatis 62 c3qitB_ not modelled 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:polyketide synthase; PDBTitle: thioesterase domain from curacin biosynthetic pathway 63 c2pseA_ not modelled 100.0 15 PDB header:oxidoreductase Chain: A: PDB Molecule:renilla-luciferin 2-monooxygenase; PDBTitle: crystal structures of the luciferase and green fluorescent2 protein from renilla reniformis 64 c2ockA_ not modelled 100.0 23 PDB header:hydrolase Chain: A: PDB Molecule:valacyclovir hydrolase; PDBTitle: crystal structure of valacyclovir hydrolase d123n mutant 65 c2yysA_ not modelled 100.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:proline iminopeptidase-related protein; PDBTitle: crystal structure of the proline iminopeptidase-related protein2 ttha1809 from thermus thermophilus hb8 66 c3jw8A_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:mgll protein; PDBTitle: crystal structure of human mono-glyceride lipase 67 d1xkla_ not modelled 100.0 12 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 68 d1r3da_ not modelled 100.0 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical protein VC1974 69 d1e89a_ not modelled 100.0 12 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 70 c3e0xB_ not modelled 100.0 21 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:lipase-esterase related protein; PDBTitle: the crystal structure of a lipase-esterase related protein2 from clostridium acetobutylicum atcc 824 71 c3c5wP_ not modelled 100.0 13 PDB header:hydrolase Chain: P: PDB Molecule:pp2a-specific methylesterase pme-1; PDBTitle: complex between pp2a-specific methylesterase pme-1 and pp2a core2 enzyme 72 d1qo7a_ not modelled 100.0 12 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 73 c3bdiA_ not modelled 100.0 27 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein ta0194; PDBTitle: crystal structure of predicted cib-like hydrolase (np_393672.1) from2 thermoplasma acidophilum at 1.45 a resolution 74 c3gzjB_ not modelled 100.0 14 PDB header:hydrolase Chain: B: PDB Molecule:polyneuridine-aldehyde esterase; PDBTitle: crystal structure of polyneuridine aldehyde esterase2 complexed with 16-epi-vellosimine 75 d3c70a1 not modelled 100.0 12 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 76 c3hjuB_ not modelled 100.0 15 PDB header:hydrolase Chain: B: PDB Molecule:monoglyceride lipase; PDBTitle: crystal structure of human monoglyceride lipase 77 c3bf7B_ not modelled 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:esterase ybff; PDBTitle: 1.1 resolution structure of ybff, a new esterase from2 escherichia coli: a unique substrate-binding crevice3 generated by domain arrangement 78 c3dqzB_ not modelled 100.0 11 PDB header:lyase Chain: B: PDB Molecule:alpha-hydroxynitrile lyase-like protein; PDBTitle: structure of the hydroxynitrile lyase from arabidopsis2 thaliana 79 c3l80A_ not modelled 100.0 11 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein smu.1393c; PDBTitle: crystal structure of smu.1393c from streptococcus mutans ua159 80 d1imja_ not modelled 100.0 25 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Ccg1/TafII250-interacting factor B (Cib) 81 d1k8qa_ not modelled 100.0 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 82 d1hlga_ not modelled 100.0 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 83 c3flaB_ not modelled 100.0 13 PDB header:hydrolase Chain: B: PDB Molecule:rifr; PDBTitle: rifr - type ii thioesterase from rifamycin nrps/pks biosynthetic2 pathway - form 1 84 c3dyvA_ not modelled 99.9 21 PDB header:hydrolase Chain: A: PDB Molecule:esterase d; PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism 85 d1tqha_ not modelled 99.9 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/lipase 86 c3llcA_ not modelled 99.9 17 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution 87 c2q0xA_ not modelled 99.9 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: alpha/beta hydrolase fold protein of unknown function 88 c3qm1A_ not modelled 99.9 11 PDB header:hydrolase Chain: A: PDB Molecule:cinnamoyl esterase; PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii 89 c2ronA_ not modelled 99.9 12 PDB header:hydrolase Chain: A: PDB Molecule:surfactin synthetase thioesterase subunit; PDBTitle: the external thioesterase of the surfactin-synthetase 90 c2hdwB_ not modelled 99.9 10 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protein pa2218; PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa 91 c3h04A_ not modelled 99.9 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50 92 c2wtmC_ not modelled 99.9 15 PDB header:hydrolase Chain: C: PDB Molecule:est1e; PDBTitle: est1e from butyrivibrio proteoclasticus 93 c3qmwD_ not modelled 99.9 14 PDB header:hydrolase Chain: D: PDB Molecule:thioesterase; PDBTitle: redj with peg molecule bound in the active site 94 c3fcyB_ not modelled 99.9 16 PDB header:hydrolase Chain: B: PDB Molecule:xylan esterase 1; PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485 95 d1l7aa_ not modelled 99.9 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acetyl xylan esterase-like 96 c1pjaA_ not modelled 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:palmitoyl-protein thioesterase 2 precursor; PDBTitle: the crystal structure of palmitoyl protein thioesterase-2 reveals the2 basis for divergent substrate specificities of the two lysosomal3 thioesterases (ppt1 and ppt2) 97 d1pjaa_ not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterases 98 d1xkta_ not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 99 d1qlwa_ not modelled 99.9 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:A novel bacterial esterase 100 c2qs9A_ not modelled 99.9 19 PDB header:structural protein Chain: A: PDB Molecule:retinoblastoma-binding protein 9; PDBTitle: crystal structure of the human retinoblastoma-binding2 protein 9 (rbbp-9). nesg target hr2978 101 c2px6A_ not modelled 99.9 11 PDB header:transferase Chain: A: PDB Molecule:thioesterase domain; PDBTitle: crystal structure of the thioesterase domain of human fatty2 acid synthase inhibited by orlistat 102 c3mveB_ not modelled 99.9 14 PDB header:lyase Chain: B: PDB Molecule:upf0255 protein vv1_0328; PDBTitle: crystal structure of a novel pyruvate decarboxylase 103 c3ksrA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:putative serine hydrolase; PDBTitle: crystal structure of a putative serine hydrolase (xcc3885) from2 xanthomonas campestris pv. campestris at 2.69 a resolution 104 c3fnbB_ not modelled 99.9 15 PDB header:hydrolase Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737; PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159 105 c2jbwB_ not modelled 99.9 19 PDB header:hydrolase Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase; PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase. 106 d1uxoa_ not modelled 99.9 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:YdeN-like 107 c3fleB_ not modelled 99.8 16 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:se_1780 protein; PDBTitle: se_1780 protein of unknown function from staphylococcus epidermidis. 108 d1ufoa_ not modelled 99.8 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical protein TT1662 109 d2jbwa1 not modelled 99.8 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:2,6-dihydropseudooxynicotine hydrolase-like 110 c3lcrA_ not modelled 99.8 17 PDB header:hydrolase Chain: A: PDB Molecule:tautomycetin biosynthetic pks; PDBTitle: thioesterase from tautomycetin biosynthhetic pathway 111 d1vlqa_ not modelled 99.8 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acetyl xylan esterase-like 112 c2qruA_ not modelled 99.8 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis 113 c2rauA_ not modelled 99.8 14 PDB header:hydrolase Chain: A: PDB Molecule:putative esterase; PDBTitle: crystal structure of a putative lipase (np_343859.1) from sulfolobus2 solfataricus at 1.85 a resolution 114 c3ilsA_ not modelled 99.8 11 PDB header:hydrolase Chain: A: PDB Molecule:aflatoxin biosynthesis polyketide synthase; PDBTitle: the thioesterase domain from pksa 115 c2qjwA_ not modelled 99.8 20 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein xcc1541; PDBTitle: crystal structure of a putative hydrolase of the alpha/beta2 superfamily (xcc1541) from xanthomonas campestris pv. campestris at3 1.35 a resolution 116 c2hu7A_ not modelled 99.8 21 PDB header:hydrolase Chain: A: PDB Molecule:acylamino-acid-releasing enzyme; PDBTitle: binding of inhibitors by acylaminoacyl peptidase 117 d1ex9a_ not modelled 99.8 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 118 c2h7xA_ not modelled 99.8 14 PDB header:hydrolase Chain: A: PDB Molecule:type i polyketide synthase pikaiv; PDBTitle: pikromycin thioesterase adduct with reduced triketide2 affinity label 119 c3lp5A_ not modelled 99.8 19 PDB header:hydrolase Chain: A: PDB Molecule:putative cell surface hydrolase; PDBTitle: the crystal structure of the putative cell surface hydrolase from2 lactobacillus plantarum wcfs1 120 d2fuka1 not modelled 99.8 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Atu1826-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0