Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	A	P	L	T	L	L	I	V	E	D	E	T	P	L	A	E	M	H	A	E	Y	I	R	H	I	P	G	F	S	Q	I	L	L	A	G	N	L	A	Q	A	R	M	M	I	E	R	F	K	P	G	L	I	L	L	D	N	Y	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	D	G	R	G	I	N	L	L	H	E	L	V	Q	A	H	Y	P	G	D	V	V	F	T	T	A	A	S	D	M	E	T	V	S	E	A	V	R	C	G	V	F	D	Y	L	I	K	P	I	A	Y	E	R	L	G	Q	T	L	T	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	R	Q	R	K	H	M	L	E	S	I	D	S	A	S	Q	K	Q	I	D	E	M	F	N	A	Y	A	R	G	E	P	K	D	E	L	P	T	G	I	D	P	L	T	L	N	A	V	R	K	L	F	K	E	P	G	V	Q	H	T	A
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.
Sequence		E	T	V	A	Q	A	L	T	I	S	R	T	T	A	R	R	Y	L	E	Y	C	A	S	R	H	L	I	I	A	E	I	V	H	G	K	V	G	R	P	Q	R	I	Y	H	S	G
Secondary structure
SS confidence
Disorder																																	?		?							?		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1zn2 chain A Region: 3 - 212 Aligned: 190 Modelled: 192 Confidence: 100.0% Identity: 16% PDB header:transcription regulator Chain: A: PDB Molecule:response regulatory protein; PDBTitle: low resolution structure of response regulator styr Phyre2 PDB 1kgs chain A Region: 5 - 213 Aligned: 204 Modelled: 206 Confidence: 100.0% Identity: 18% PDB header:dna binding protein Chain: A: PDB Molecule:dna binding response regulator d; PDBTitle: crystal structure at 1.50 a of an ompr/phob homolog from thermotoga2 maritima Phyre2 PDB 3r0j chain A Region: 2 - 205 Aligned: 196 Modelled: 204 Confidence: 100.0% Identity: 20% PDB header:dna binding protein Chain: A: PDB Molecule:possible two component system response transcriptional PDBTitle: structure of phop from mycobacterium tuberculosis Phyre2 PDB 3c3w chain B Region: 5 - 212 Aligned: 198 Modelled: 208 Confidence: 100.0% Identity: 18% PDB header:transcription Chain: B: PDB Molecule:two component transcriptional regulatory protein devr; PDBTitle: crystal structure of the mycobacterium tuberculosis hypoxic response2 regulator dosr Phyre2 PDB 1ys7 chain B Region: 3 - 205 Aligned: 200 Modelled: 203 Confidence: 100.0% Identity: 16% PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulatory protein prra; PDBTitle: crystal structure of the response regulator protein prra comlexed with2 mg2+ Phyre2 PDB 1rnl chain A Region: 3 - 212 Aligned: 189 Modelled: 189 Confidence: 100.0% Identity: 23% PDB header:signal transduction protein Chain: A: PDB Molecule:nitrate/nitrite response regulator protein narl; PDBTitle: the nitrate/nitrite response regulator protein narl from narl Phyre2 PDB 2ayx chain A Region: 2 - 126 Aligned: 123 Modelled: 125 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:sensor kinase protein rcsc; PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain Phyre2 PDB 1s8n chain A Region: 4 - 205 Aligned: 187 Modelled: 202 Confidence: 100.0% Identity: 24% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 3q9s chain A Region: 6 - 213 Aligned: 199 Modelled: 208 Confidence: 100.0% Identity: 18% PDB header:dna binding protein Chain: A: PDB Molecule:dna-binding response regulator; PDBTitle: crystal structure of rra(1-215) from deinococcus radiodurans Phyre2 PDB 3bre chain A Region: 4 - 155 Aligned: 151 Modelled: 152 Confidence: 100.0% Identity: 19% PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: crystal structure of p.aeruginosa pa3702 Phyre2 PDB 1a04 chain A domain 2 Region: 3 - 131 Aligned: 129 Modelled: 129 Confidence: 100.0% Identity: 26% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 3eul chain B Region: 2 - 125 Aligned: 124 Modelled: 124 Confidence: 100.0% Identity: 16% PDB header:transcription Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis Phyre2 PDB 1a2o chain B Region: 1 - 225 Aligned: 216 Modelled: 224 Confidence: 99.9% Identity: 20% PDB header:bacterial chemotaxis Chain: B: PDB Molecule:cheb methylesterase; PDBTitle: structural basis for methylesterase cheb regulation by a2 phosphorylation-activated domain Phyre2 PDB 3cz5 chain B Region: 3 - 130 Aligned: 128 Modelled: 128 Confidence: 99.9% Identity: 17% PDB header:transcription regulator Chain: B: PDB Molecule:two-component response regulator, luxr family; PDBTitle: crystal structure of two-component response regulator, luxr family,2 from aurantimonas sp. si85-9a1 Phyre2 PDB 3eq2 chain A Region: 6 - 154 Aligned: 144 Modelled: 149 Confidence: 99.9% Identity: 24% PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: structure of hexagonal crystal form of pseudomonas2 aeruginosa rssb Phyre2 PDB 3b2n chain A Region: 5 - 122 Aligned: 118 Modelled: 118 Confidence: 99.9% Identity: 25% PDB header:transcription Chain: A: PDB Molecule:uncharacterized protein q99uf4; PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus Phyre2 PDB 1ny5 chain A Region: 5 - 138 Aligned: 132 Modelled: 134 Confidence: 99.9% Identity: 21% PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of sigm54 activator (aaa+ atpase) in the inactive2 state Phyre2 PDB 1jbe chain A Region: 2 - 127 Aligned: 125 Modelled: 126 Confidence: 99.9% Identity: 22% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 1w25 chain B Region: 6 - 133 Aligned: 126 Modelled: 128 Confidence: 99.9% Identity: 21% PDB header:signaling protein Chain: B: PDB Molecule:stalked-cell differentiation controlling protein; PDBTitle: response regulator pled in complex with c-digmp Phyre2 PDB 3i5a chain A Region: 6 - 150 Aligned: 144 Modelled: 145 Confidence: 99.9% Identity: 19% PDB header:signaling protein Chain: A: PDB Molecule:response regulator/ggdef domain protein; PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae Phyre2 PDB 1uly chain A Region: 168 - 223 Aligned: 56 Modelled: 54 Confidence: 96.9% Identity: 18% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Hypothetical protein PH1932 Phyre2 1 c1zn2A_ 2 c1kgsA_ 3 c3r0jA_ 4 c3c3wB_ 5 c1ys7B_ 6 c1rnlA_ 7 c2ayxA_ 8 d1s8na_ 9 c3q9sA_ 10 c3breA_ 11 d1a04a2 12 c3eulB_ 13 c1a2oB_ 14 c3cz5B_ 15 c3eq2A_ 16 c3b2nA_ 17 c1ny5A_ 18 d1jbea_ 19 c1w25B_ 20 c3i5aA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 d1ulya_ 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499