Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	T	K	K	I	F	K	H	I	P	W	V	I	L	G	I	I	G	A	F	C	L	A	V	V	A	L	R	R	G	E	H	I	S	A	L	W	I	V	V	A	S	V	S	V	Y	L	V	A	Y	R	Y	Y	S	L	Y	I	A	Q
Secondary structure
SS confidence
Disorder		?	?																											?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	V	M	K	L	D	P	T	R	A	T	P	A	V	I	N	N	D	G	L	N	Y	V	P	T	N	R	Y	V	L	F	G	H	H	F	A	A	I	A	G	A	G	P	L	V	G	P	V	L	A	A	Q	M	G	Y	L	P	G	T	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		W	L	L	A	G	V	V	L	A	G	A	V	Q	D	F	M	V	L	F	I	S	S	R	R	N	G	A	S	L	G	E	M	I	K	E	E	M	G	P	V	P	G	T	I	A	L	F	G	C	F	L	I	M	I	I	I	L	A	V	L
Secondary structure
SS confidence
Disorder																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	L	I	V	V	K	A	L	A	E	S	P	W	G	V	F	T	V	C	S	T	V	P	I	A	L	F	M	G	I	Y	M	R	F	I	R	P	G	R	V	G	E	V	S	V	I	G	I	V	L	L	V	A	S	I	Y	F	G	G	V
Secondary structure
SS confidence
Disorder											?																											?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		I	A	H	D	P	Y	W	G	P	A	L	T	F	K	D	T	T	I	T	F	A	L	I	G	Y	A	F	V	S	A	L	L	P	V	W	L	I	L	A	P	R	D	Y	L	A	T	F	L	K	I	G	V	I	V	G	L	A	L	G	I
Secondary structure
SS confidence
Disorder				?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	V	L	N	P	E	L	K	M	P	A	M	T	Q	Y	I	D	G	T	G	P	L	W	K	G	A	L	F	P	F	L	F	I	T	I	A	C	G	A	V	S	G	F	H	A	L	I	S	S	G	T	T	P	K	L	L	A	N	E	T
Secondary structure
SS confidence
Disorder															?			?	?	?	?	?	?																									?	?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		D	A	R	F	I	G	Y	G	A	M	L	M	E	S	F	V	A	I	M	A	L	V	A	A	S	I	I	E	P	G	L	Y	F	A	M	N	T	P	P	A	G	L	G	I	T	M	P	N	L	H	E	M	G	G	E	N	A	P	I	I
Secondary structure
SS confidence
Disorder																																?	?	?	?		?	?	?	?	?	?	?	?	?							?	?	?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		M	A	Q	L	K	D	V	T	A	H	A	A	A	T	V	S	S	W	G	F	V	I	S	P	E	Q	I	L	Q	T	A	K	D	I	G	E	P	S	V	L	N	R	A	G	G	A	P	T	L	A	V	G	I	A	H	V	F	H	K	V
Secondary structure
SS confidence
Disorder		?	?	?		?	?	?	?	?	?	?	?	?		?	?	?	?	?	?	?	?	?												?	?	?	?	?	?	?	?																?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		L	P	M	A	D	M	G	F	W	Y	H	F	G	I	L	F	E	A	L	F	I	L	T	A	L	D	A	G	T	R	S	G	R	F	M	L	Q	D	L	L	G	N	F	I	P	F	L	K	K	T	D	S	L	V	A	G	I	I	G	T
Secondary structure
SS confidence
Disorder			?	?																																										?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		A	G	C	V	G	L	W	G	Y	L	L	Y	Q	G	V	V	D	P	L	G	G	V	K	S	L	W	P	L	F	G	I	S	N	Q	M	L	A	A	V	A	L	V	L	G	T	V	V	L	I	K	M	K	R	T	Q	Y	I	W	V	T
Secondary structure
SS confidence
Disorder														?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		V	V	P	A	V	W	L	L	I	C	T	T	W	A	L	G	L	K	L	F	S	T	N	P	Q	M	E	G	F	F	Y	M	A	S	Q	Y	K	E	K	I	A	N	G	T	D	L	T	A	Q	Q	I	A	N	M	N	H	I	V	V	N
Secondary structure
SS confidence
Disorder																																											?	?	?	?	?	?	?	?	?	?							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.
Sequence		N	Y	T	N	A	G	L	S	I	L	F	L	I	V	V	Y	S	I	I	F	Y	G	F	K	T	W	L	A	V	R	N	S	D	K	R	T	D	K	E	T	P	Y	V	P	I	P	E	G	G	V	K	I	S	S	H	H
Secondary structure
SS confidence
Disorder			?																														?	?	?	?	?	?	?													?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3gia chain A Region: 86 - 699 Aligned: 425 Modelled: 425 Confidence: 98.0% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:uncharacterized protein mj0609; PDBTitle: crystal structure of apct transporter Phyre2 PDB 2xq2 chain A Region: 38 - 715 Aligned: 481 Modelled: 481 Confidence: 97.4% Identity: 16% PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: structure of the k294a mutant of vsglt Phyre2 PDB 2jln chain A Region: 59 - 705 Aligned: 448 Modelled: 473 Confidence: 97.2% Identity: 14% PDB header:membrane protein Chain: A: PDB Molecule:mhp1; PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter Phyre2 PDB 3dh4 chain A Region: 85 - 678 Aligned: 465 Modelled: 474 Confidence: 88.3% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus Phyre2 PDB 3lrc chain C Region: 85 - 616 Aligned: 374 Modelled: 374 Confidence: 82.6% Identity: 13% PDB header:transport protein Chain: C: PDB Molecule:arginine/agmatine antiporter; PDBTitle: structure of e. coli adic (p1) Phyre2 PDB 3a8q chain B Region: 340 - 349 Aligned: 10 Modelled: 10 Confidence: 31.6% Identity: 70% PDB header:signaling protein Chain: B: PDB Molecule:t-lymphoma invasion and metastasis-inducing PDBTitle: low-resolution crystal structure of the tiam2 phccex domain Phyre2 PDB 3a8n chain A Region: 340 - 351 Aligned: 12 Modelled: 12 Confidence: 29.7% Identity: 58% PDB header:signaling protein Chain: A: PDB Molecule:t-lymphoma invasion and metastasis-inducing PDBTitle: crystal structure of the tiam1 phccex domain Phyre2 PDB 3pl0 chain B Region: 66 - 83 Aligned: 18 Modelled: 18 Confidence: 21.5% Identity: 33% PDB header:biosynthetic protein Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a bsma homolog (mpe_a2762) from methylobium2 petroleophilum pm1 at 1.91 a resolution Phyre2 PDB 1rp4 chain A Region: 340 - 361 Aligned: 22 Modelled: 22 Confidence: 17.7% Identity: 41% Fold: ERO1-like Superfamily: ERO1-like Family: ERO1-like Phyre2 PDB 3hd6 chain A Region: 32 - 67 Aligned: 35 Modelled: 36 Confidence: 16.3% Identity: 11% PDB header:membrane protein, transport protein Chain: A: PDB Molecule:ammonium transporter rh type c; PDBTitle: crystal structure of the human rhesus glycoprotein rhcg Phyre2 PDB 2jp3 chain A Region: 665 - 701 Aligned: 37 Modelled: 37 Confidence: 14.1% Identity: 16% PDB header:transcription Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4; PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles Phyre2 PDB 3b9y chain A Region: 32 - 67 Aligned: 35 Modelled: 36 Confidence: 12.3% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:ammonium transporter family rh-like protein; PDBTitle: crystal structure of the nitrosomonas europaea rh protein Phyre2 PDB 2k9p chain A Region: 576 - 609 Aligned: 34 Modelled: 34 Confidence: 12.3% Identity: 24% PDB header:membrane protein Chain: A: PDB Molecule:pheromone alpha factor receptor; PDBTitle: structure of tm1_tm2 in lppg micelles Phyre2 PDB 2axt chain J domain 1 Region: 44 - 57 Aligned: 14 Modelled: 14 Confidence: 11.5% Identity: 21% Fold: Single transmembrane helix Superfamily: Photosystem II reaction center protein J, PsbJ Family: PsbJ-like Phyre2 PDB 2bfd chain B domain 2 Region: 353 - 377 Aligned: 25 Modelled: 25 Confidence: 11.4% Identity: 8% Fold: TK C-terminal domain-like Superfamily: TK C-terminal domain-like Family: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain Phyre2 PDB 3ahr chain A Region: 340 - 348 Aligned: 9 Modelled: 9 Confidence: 10.6% Identity: 56% PDB header:oxidoreductase Chain: A: PDB Molecule:ero1-like protein alpha; PDBTitle: inactive human ero1 Phyre2 PDB 2awi chain A domain 1 Region: 349 - 365 Aligned: 17 Modelled: 17 Confidence: 10.5% Identity: 41% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: PrgX N-terminal domain-like Phyre2 PDB 3chx chain E Region: 93 - 107 Aligned: 15 Modelled: 15 Confidence: 9.7% Identity: 40% PDB header:membrane protein Chain: E: PDB Molecule:pmob; PDBTitle: crystal structure of methylosinus trichosporium ob3b2 particulate methane monooxygenase (pmmo) Phyre2 PDB 1qs0 chain B domain 2 Region: 353 - 378 Aligned: 26 Modelled: 26 Confidence: 9.2% Identity: 19% Fold: TK C-terminal domain-like Superfamily: TK C-terminal domain-like Family: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain Phyre2 PDB 1h5p chain A Region: 141 - 155 Aligned: 15 Modelled: 15 Confidence: 9.2% Identity: 27% Fold: SAND domain-like Superfamily: SAND domain-like Family: SAND domain Phyre2 1 c3giaA_ 2 c2xq2A_ 3 c2jlnA_ 4 c3dh4A_ 5 c3lrcC_ 6 c3a8qB_ 7 c3a8nA_ 8 c3pl0B_ 9 d1rp4a_ 10 c3hd6A_ 11 c2jp3A_ 12 c3b9yA_ 13 c2k9pA_ 14 d2axtj1 15 d2bfdb2 16 c3ahrA_ 17 d2awia1 18 c3chxE_ 19 d1qs0b2 20 d1h5pa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52