Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	Y	I	K	I	H	A	L	D	N	V	A	V	A	L	A	D	L	A	E	G	T	E	V	S	V	D	N	Q	T	V	T	L	R	Q	D	V	A	R	G	H	K	F	A	L	T	D	I	A	K	G	A	N	V	I	K	Y	G	L
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	I	G	Y	A	L	A	D	I	A	A	G	V	H	V	H	A	H	N	T	R	T	N	L	S	D	L	D	Q	Y	R	Y	Q	P	D	F	Q	D	L	P	A	Q	A	A	D	R	E	V	Q	I	Y	R	R	A	N	G	D	V	G	V
Secondary structure
SS confidence
Disorder																								?		?	?	?	?	?	?	?		?				?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	N	E	L	W	I	L	P	T	V	G	C	V	N	G	I	A	R	Q	I	Q	N	R	F	L	K	E	T	N	N	A	E	G	T	D	G	V	F	L	F	S	H	T	Y	G	C	S	Q	L	G	D	D	H	I	N	T	R	T	M	L
Secondary structure
SS confidence
Disorder																												?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	N	M	V	R	H	P	N	A	G	A	V	L	V	I	G	L	G	C	E	N	N	Q	V	A	A	F	R	E	T	L	G	D	I	D	P	E	R	V	H	F	M	I	C	Q	Q	Q	D	D	E	I	E	A	G	I	E	H	L	H	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	Y	N	V	M	R	N	D	K	R	E	P	G	K	L	S	E	L	K	F	G	L	E	C	G	G	S	D	G	L	S	G	I	T	A	N	P	M	L	G	R	F	S	D	Y	V	I	A	N	G	G	T	T	V	L	T	E	V	P	E
Secondary structure
SS confidence
Disorder									?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		M	F	G	A	E	Q	L	L	M	D	H	C	R	D	E	A	T	F	E	K	L	V	T	M	V	N	D	F	K	Q	Y	F	I	A	H	D	Q	P	I	Y	E	N	P	S	P	G	N	K	A	G	G	I	T	T	L	E	D	K	S	L
Secondary structure
SS confidence
Disorder																																							?	?	?	?	?	?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	C	T	Q	K	A	G	S	S	V	V	V	D	V	L	R	Y	G	E	R	L	K	T	P	G	L	N	L	L	S	A	P	G	N	D	A	V	A	T	S	A	L	A	G	A	G	C	H	M	V	L	F	S	T	G	R	G	T	P	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		G	G	F	V	P	T	V	K	I	A	T	N	S	E	L	A	A	K	K	K	H	W	I	D	F	D	A	G	Q	L	I	H	G	K	A	M	P	Q	L	L	E	E	F	I	D	T	I	V	E	F	A	N	G	K	Q	T	C	N	E	R
Secondary structure
SS confidence
Disorder																																	?																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.
Sequence		N	D	F	R	E	L	A	I	F	K	S	G	V	T	L
Secondary structure
SS confidence
Disorder		?									?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3k3s chain G Region: 1 - 84 Aligned: 84 Modelled: 83 Confidence: 100.0% Identity: 98% PDB header:hydrolase Chain: G: PDB Molecule:altronate hydrolase; PDBTitle: crystal structure of altronate hydrolase (fragment 1-84) from shigella2 flexneri. Phyre2 PDB 3laz chain B Region: 2 - 82 Aligned: 80 Modelled: 81 Confidence: 99.9% Identity: 33% PDB header:lyase Chain: B: PDB Molecule:d-galactarate dehydratase; PDBTitle: the crystal structure of the n-terminal domain of d-2 galactarate dehydratase from escherichia coli cft073 Phyre2 PDB 3frn chain A Region: 4 - 119 Aligned: 94 Modelled: 116 Confidence: 89.8% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:flagellar protein flga; PDBTitle: crystal structure of flagellar protein flga from thermotoga maritima2 msb8 Phyre2 PDB 1vme chain A domain 1 Region: 121 - 243 Aligned: 119 Modelled: 123 Confidence: 88.1% Identity: 11% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: Flavodoxin-related Phyre2 PDB 1qd1 chain A Region: 52 - 168 Aligned: 103 Modelled: 117 Confidence: 82.1% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:formiminotransferase-cyclodeaminase; PDBTitle: the crystal structure of the formiminotransferase domain of2 formiminotransferase-cyclodeaminase. Phyre2 PDB 3ff1 chain B Region: 135 - 245 Aligned: 95 Modelled: 111 Confidence: 79.9% Identity: 15% PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: structure of glucose 6-phosphate isomerase from staphylococcus aureus Phyre2 PDB 2zdr chain A domain 1 Region: 13 - 81 Aligned: 55 Modelled: 67 Confidence: 77.5% Identity: 27% Fold: beta-clip Superfamily: AFP III-like domain Family: AFP III-like domain Phyre2 PDB 3hr4 chain C Region: 121 - 247 Aligned: 127 Modelled: 127 Confidence: 75.4% Identity: 15% PDB header:oxidoreductase/metal binding protein Chain: C: PDB Molecule:nitric oxide synthase, inducible; PDBTitle: human inos reductase and calmodulin complex Phyre2 PDB 1c7q chain A Region: 135 - 245 Aligned: 95 Modelled: 111 Confidence: 74.9% Identity: 13% Fold: SIS domain Superfamily: SIS domain Family: Phosphoglucose isomerase, PGI Phyre2 PDB 1vli chain A domain 1 Region: 13 - 83 Aligned: 55 Modelled: 55 Confidence: 74.2% Identity: 25% Fold: beta-clip Superfamily: AFP III-like domain Family: AFP III-like domain Phyre2 PDB 3g8r chain A Region: 13 - 81 Aligned: 57 Modelled: 69 Confidence: 69.6% Identity: 25% PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 Phyre2 PDB 3m7o chain B Region: 18 - 92 Aligned: 73 Modelled: 75 Confidence: 67.2% Identity: 21% PDB header:immune system Chain: B: PDB Molecule:lymphocyte antigen 86; PDBTitle: crystal structure of mouse md-1 in complex with phosphatidylcholine Phyre2 PDB 1tt9 chain B Region: 52 - 169 Aligned: 104 Modelled: 118 Confidence: 66.7% Identity: 19% PDB header:transferase, lyase Chain: B: PDB Molecule:formimidoyltransferase-cyclodeaminase PDBTitle: structure of the bifunctional and golgi associated2 formiminotransferase cyclodeaminase octamer Phyre2 PDB 1xuz chain A Region: 13 - 81 Aligned: 55 Modelled: 56 Confidence: 63.6% Identity: 29% PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol Phyre2 PDB 2hnb chain A Region: 123 - 246 Aligned: 124 Modelled: 124 Confidence: 60.8% Identity: 18% PDB header:electron transport Chain: A: PDB Molecule:protein mioc; PDBTitle: solution structure of a bacterial holo-flavodoxin Phyre2 PDB 1b1c chain A Region: 123 - 247 Aligned: 124 Modelled: 125 Confidence: 57.7% Identity: 15% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: Cytochrome p450 reductase N-terminal domain-like Phyre2 PDB 1vli chain A Region: 13 - 55 Aligned: 43 Modelled: 43 Confidence: 55.7% Identity: 26% PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution Phyre2 PDB 2nu7 chain B domain 1 Region: 170 - 240 Aligned: 67 Modelled: 71 Confidence: 53.4% Identity: 13% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 2q9u chain B Region: 122 - 254 Aligned: 132 Modelled: 133 Confidence: 46.9% Identity: 10% PDB header:oxidoreductase Chain: B: PDB Molecule:a-type flavoprotein; PDBTitle: crystal structure of the flavodiiron protein from giardia2 intestinalis Phyre2 PDB 1euc chain B domain 1 Region: 170 - 240 Aligned: 69 Modelled: 71 Confidence: 46.6% Identity: 12% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 1 c3k3sG_ 2 c3lazB_ 3 c3frnA_ 4 d1vmea1 5 c1qd1A_ 6 c3ff1B_ 7 d2zdra1 8 c3hr4C_ 9 d1c7qa_ 10 d1vlia1 11 c3g8rA_ 12 c3m7oB_ 13 c1tt9B_ 14 c1xuzA_ 15 c2hnbA_ 16 d1b1ca_ 17 c1vliA_ 18 d2nu7b1 19 c2q9uB_ 20 d1eucb1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3k3sG_ 100.0 98 PDB header:hydrolase Chain: G: PDB Molecule:altronate hydrolase; PDBTitle: crystal structure of altronate hydrolase (fragment 1-84) from shigella2 flexneri. 2 c3lazB_ 99.9 33 PDB header:lyase Chain: B: PDB Molecule:d-galactarate dehydratase; PDBTitle: the crystal structure of the n-terminal domain of d-2 galactarate dehydratase from escherichia coli cft073 3 c3frnA_ 89.8 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:flagellar protein flga; PDBTitle: crystal structure of flagellar protein flga from thermotoga maritima2 msb8 4 d1vmea1 88.1 11 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 5 c1qd1A_ 82.1 17 PDB header:transferase Chain: A: PDB Molecule:formiminotransferase-cyclodeaminase; PDBTitle: the crystal structure of the formiminotransferase domain of2 formiminotransferase-cyclodeaminase. 6 c3ff1B_ 79.9 15 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: structure of glucose 6-phosphate isomerase from staphylococcus aureus 7 d2zdra1 77.5 27 Fold:beta-clip Superfamily:AFP III-like domain Family:AFP III-like domain 8 c3hr4C_ 75.4 15 PDB header:oxidoreductase/metal binding protein Chain: C: PDB Molecule:nitric oxide synthase, inducible; PDBTitle: human inos reductase and calmodulin complex 9 d1c7qa_ 74.9 13 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 10 d1vlia1 74.2 25 Fold:beta-clip Superfamily:AFP III-like domain Family:AFP III-like domain 11 c3g8rA_ 69.6 25 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 12 c3m7oB_ 67.2 21 PDB header:immune system Chain: B: PDB Molecule:lymphocyte antigen 86; PDBTitle: crystal structure of mouse md-1 in complex with phosphatidylcholine 13 c1tt9B_ 66.7 19 PDB header:transferase, lyase Chain: B: PDB Molecule:formimidoyltransferase-cyclodeaminase PDBTitle: structure of the bifunctional and golgi associated2 formiminotransferase cyclodeaminase octamer 14 c1xuzA_ 63.6 29 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 15 c2hnbA_ 60.8 18 PDB header:electron transport Chain: A: PDB Molecule:protein mioc; PDBTitle: solution structure of a bacterial holo-flavodoxin 16 d1b1ca_ 57.7 15 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Cytochrome p450 reductase N-terminal domain-like 17 c1vliA_ 55.7 26 PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution 18 d2nu7b1 53.4 13 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 19 c2q9uB_ 46.9 10 PDB header:oxidoreductase Chain: B: PDB Molecule:a-type flavoprotein; PDBTitle: crystal structure of the flavodiiron protein from giardia2 intestinalis 20 d1eucb1 46.6 12 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 21 d1ja1a2 not modelled 45.7 16 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Cytochrome p450 reductase N-terminal domain-like 22 c3b8hA_ not modelled 41.8 26 PDB header:biosynthetic protein/transferase Chain: A: PDB Molecule:elongation factor 2; PDBTitle: structure of the eef2-exoa(e546a)-nad+ complex 23 c2ohiB_ not modelled 41.4 13 PDB header:oxidoreductase Chain: B: PDB Molecule:type a flavoprotein fpra; PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state 24 d2f69a2 not modelled 41.2 18 Fold:beta-clip Superfamily:SET domain Family:Histone lysine methyltransferases 25 c3hjbA_ not modelled 40.1 18 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: 1.5 angstrom crystal structure of glucose-6-phosphate isomerase from2 vibrio cholerae. 26 c1ychD_ not modelled 40.0 13 PDB header:oxidoreductase Chain: D: PDB Molecule:nitric oxide reductase; PDBTitle: x-ray crystal structures of moorella thermoacetica fpra.2 novel diiron site structure and mechanistic insights into3 a scavenging nitric oxide reductase 27 c3tr5C_ not modelled 38.9 26 PDB header:translation Chain: C: PDB Molecule:peptide chain release factor 3; PDBTitle: structure of a peptide chain release factor 3 (prfc) from coxiella2 burnetii 28 c2z64C_ not modelled 35.0 14 PDB header:immune system Chain: C: PDB Molecule:lymphocyte antigen 96; PDBTitle: crystal structure of mouse tlr4 and mouse md-2 complex 29 c3cnlA_ not modelled 34.5 24 PDB header:signaling protein Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of gnp-bound ylqf from t. maritima 30 c1vmeB_ not modelled 34.3 13 PDB header:electron transport Chain: B: PDB Molecule:flavoprotein; PDBTitle: crystal structure of flavoprotein (tm0755) from thermotoga maritima at2 1.80 a resolution 31 c3nbuC_ not modelled 34.3 17 PDB header:isomerase Chain: C: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: crystal structure of pgi glucosephosphate isomerase 32 c2elfA_ not modelled 34.0 15 PDB header:translation Chain: A: PDB Molecule:protein translation elongation factor 1a; PDBTitle: crystal structure of the selb-like elongation factor ef-pyl2 from methanosarcina mazei 33 c3cdzA_ not modelled 33.4 24 PDB header:blood clotting Chain: A: PDB Molecule:coagulation factor viii heavy chain; PDBTitle: crystal structure of human factor viii 34 c2j69D_ not modelled 33.1 26 PDB header:hydrolase Chain: D: PDB Molecule:bacterial dynamin-like protein; PDBTitle: bacterial dynamin-like protein bdlp 35 d1puja_ not modelled 33.0 36 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:G proteins 36 d1ycga1 not modelled 32.7 10 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 37 c3izq1_ not modelled 32.5 21 PDB header:ribosomal protein,hydrolase Chain: 1: PDB Molecule:elongation factor 1 alpha-like protein; PDBTitle: structure of the dom34-hbs1-gdpnp complex bound to a translating2 ribosome 38 d1e5da1 not modelled 31.1 10 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 39 c1g7tA_ not modelled 29.4 22 PDB header:translation Chain: A: PDB Molecule:translation initiation factor if2/eif5b; PDBTitle: x-ray structure of translation initiation factor if2/eif5b2 complexed with gdpnp 40 c2q8nB_ not modelled 27.4 19 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: crystal structure of glucose-6-phosphate isomerase (ec2 5.3.1.9) (tm1385) from thermotoga maritima at 1.82 a3 resolution 41 d1ag9a_ not modelled 27.2 16 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 42 c3degC_ not modelled 26.5 24 PDB header:ribosome Chain: C: PDB Molecule:gtp-binding protein lepa; PDBTitle: complex of elongating escherichia coli 70s ribosome and ef4(lepa)-2 gmppnp 43 d1ykga1 not modelled 25.7 15 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Cytochrome p450 reductase N-terminal domain-like 44 c3ka5A_ not modelled 25.1 40 PDB header:chaperone Chain: A: PDB Molecule:ribosome-associated protein y (psrp-1); PDBTitle: crystal structure of ribosome-associated protein y (psrp-1)2 from clostridium acetobutylicum. northeast structural3 genomics consortium target id car123a 45 c2cmgA_ not modelled 24.7 9 PDB header:transferase Chain: A: PDB Molecule:spermidine synthase; PDBTitle: crystal structure of spermidine synthase from helicobacter2 pylori 46 c1t10A_ not modelled 24.5 13 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: phosphoglucose isomerase from leishmania mexicana in complex with2 substrate d-fructose-6-phosphate 47 c3k2tA_ not modelled 24.4 40 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lmo2511 protein; PDBTitle: crystal structure of lmo2511 protein from listeria2 monocytogenes, northeast structural genomics consortium3 target lkr84a 48 d1h3ia2 not modelled 22.8 8 Fold:beta-clip Superfamily:SET domain Family:Histone lysine methyltransferases 49 c3f9xA_ not modelled 22.8 38 PDB header:transferase Chain: A: PDB Molecule:histone-lysine n-methyltransferase setd8; PDBTitle: structural insights into lysine multiple methylation by set2 domain methyltransferases, set8-y334f / h4-lys20me2 /3 adohcy 50 c2ywfA_ not modelled 22.6 28 PDB header:translation Chain: A: PDB Molecule:gtp-binding protein lepa; PDBTitle: crystal structure of gmppnp-bound lepa from aquifex aeolicus 51 c3h6lA_ not modelled 22.5 15 PDB header:transferase Chain: A: PDB Molecule:histone-lysine n-methyltransferase setd2; PDBTitle: methyltransferase domain of human set domain-containing protein 2 52 d1o0ya_ not modelled 22.0 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 53 d2fcra_ not modelled 21.9 13 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 54 d1oboa_ not modelled 21.7 15 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 55 c3opeA_ not modelled 20.9 31 PDB header:transferase Chain: A: PDB Molecule:probable histone-lysine n-methyltransferase ash1l; PDBTitle: structural basis of auto-inhibitory mechanism of histone2 methyltransferase 56 d1bvyf_ not modelled 20.6 18 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 57 c1bvyF_ not modelled 20.6 18 PDB header:oxidoreductase Chain: F: PDB Molecule:protein (cytochrome p450 bm-3); PDBTitle: complex of the heme and fmn-binding domains of the2 cytochrome p450(bm-3) 58 c1zo1I_ not modelled 20.5 15 PDB header:translation/rna Chain: I: PDB Molecule:translation initiation factor 2; PDBTitle: if2, if1, and trna fitted to cryo-em data of e. coli 70s2 initiation complex 59 c1x5bA_ not modelled 20.3 17 PDB header:protein binding Chain: A: PDB Molecule:signal transducing adaptor molecule 2; PDBTitle: the solution structure of the vhs domain of human signal2 transducing adaptor molecule 2 60 c2bm0A_ not modelled 20.1 21 PDB header:elongation factor Chain: A: PDB Molecule:elongation factor g; PDBTitle: ribosomal elongation factor g (ef-g) fusidic acid resistant2 mutant t84a 61 c2o2cB_ not modelled 20.0 16 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase, glycosomal; PDBTitle: crystal structure of phosphoglucose isomerase from t. brucei2 containing glucose-6-phosphate in the active site 62 d2nqra2 not modelled 20.0 20 Fold:MoeA N-terminal region -like Superfamily:MoeA N-terminal region -like Family:MoeA N-terminal region -like 63 d1c8ba_ not modelled 19.8 20 Fold:Phosphorylase/hydrolase-like Superfamily:HybD-like Family:Germination protease 64 c3mu3A_ not modelled 19.3 14 PDB header:immune system Chain: A: PDB Molecule:protein md-1; PDBTitle: crystal structure of chicken md-1 complexed with lipid iva 65 d1ml9a_ not modelled 19.3 46 Fold:beta-clip Superfamily:SET domain Family:Histone lysine methyltransferases 66 c2wu8A_ not modelled 19.1 15 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: structural studies of phosphoglucose isomerase from2 mycobacterium tuberculosis h37rv 67 c3o3nB_ not modelled 19.0 17 PDB header:lyase Chain: B: PDB Molecule:beta-subunit 2-hydroxyacyl-coa dehydratase; PDBTitle: (r)-2-hydroxyisocaproyl-coa dehydratase in complex with its substrate2 (r)-2-hydroxyisocaproyl-coa 68 d1iata_ not modelled 18.9 18 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 69 c1s0uA_ not modelled 18.9 18 PDB header:translation Chain: A: PDB Molecule:translation initiation factor 2 gamma subunit; PDBTitle: eif2gamma apo 70 d1pkla3 not modelled 18.5 22 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:Pyruvate kinase, C-terminal domain 71 c2qv5A_ not modelled 17.6 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu2773; PDBTitle: crystal structure of uncharacterized protein atu2773 from2 agrobacterium tumefaciens c58 72 c3hlyA_ not modelled 17.5 14 PDB header:flavoprotein Chain: A: PDB Molecule:flavodoxin-like domain; PDBTitle: crystal structure of the flavodoxin-like domain from2 synechococcus sp q5mzp6_synp6 protein. northeast structural3 genomics consortium target snr135d. 73 d1wu2a2 not modelled 17.2 27 Fold:MoeA N-terminal region -like Superfamily:MoeA N-terminal region -like Family:MoeA N-terminal region -like 74 d1mvha_ not modelled 17.1 31 Fold:beta-clip Superfamily:SET domain Family:Histone lysine methyltransferases 75 c1mvhA_ not modelled 17.1 31 PDB header:transferase Chain: A: PDB Molecule:cryptic loci regulator 4; PDBTitle: structure of the set domain histone lysine2 methyltransferase clr4 76 d1q50a_ not modelled 16.8 13 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 77 d1nuia2 not modelled 16.4 67 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:DNA primase zinc finger 78 c2xexA_ not modelled 16.3 16 PDB header:translation Chain: A: PDB Molecule:elongation factor g; PDBTitle: crystal structure of staphylococcus aureus elongation factor2 g 79 d2f23a2 not modelled 16.1 23 Fold:FKBP-like Superfamily:FKBP-like Family:GreA transcript cleavage factor, C-terminal domain 80 d1dvpa1 not modelled 15.6 17 Fold:alpha-alpha superhelix Superfamily:ENTH/VHS domain Family:VHS domain 81 d1to6a_ not modelled 15.4 18 Fold:Glycerate kinase I Superfamily:Glycerate kinase I Family:Glycerate kinase I 82 c3lpmA_ not modelled 15.3 18 PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of putative methyltransferase small domain protein2 from listeria monocytogenes 83 c2r3aA_ not modelled 15.3 23 PDB header:transferase Chain: A: PDB Molecule:histone-lysine n-methyltransferase suv39h2; PDBTitle: methyltransferase domain of human suppressor of variegation2 3-9 homolog 2 84 c3oa3A_ not modelled 15.1 10 PDB header:lyase Chain: A: PDB Molecule:aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 coccidioides immitis 85 c3o3nA_ not modelled 15.1 9 PDB header:lyase Chain: A: PDB Molecule:alpha-subunit 2-hydroxyisocaproyl-coa dehydratase; PDBTitle: (r)-2-hydroxyisocaproyl-coa dehydratase in complex with its substrate2 (r)-2-hydroxyisocaproyl-coa 86 d1txna_ not modelled 14.5 21 Fold:Coproporphyrinogen III oxidase Superfamily:Coproporphyrinogen III oxidase Family:Coproporphyrinogen III oxidase 87 d1u0fa_ not modelled 14.1 17 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 88 c1lnsA_ not modelled 14.1 10 PDB header:hydrolase Chain: A: PDB Molecule:x-prolyl dipeptidyl aminopetidase; PDBTitle: crystal structure analysis of the x-prolyl dipeptidyl2 aminopeptidase from lactococcus lactis 89 c2e59A_ not modelled 14.0 18 PDB header:lipid binding protein Chain: A: PDB Molecule:lymphocyte antigen 96; PDBTitle: crystal structure of human md-2 in complex with lipid iva 90 c3by5A_ not modelled 14.0 27 PDB header:biosynthetic protein Chain: A: PDB Molecule:cobalamin biosynthesis protein; PDBTitle: crystal structure of cobalamin biosynthesis protein chig from2 agrobacterium tumefaciens str. c58 91 d3by5a1 not modelled 14.0 27 Fold:CobE/GbiG C-terminal domain-like Superfamily:CobE/GbiG C-terminal domain-like Family:CobE/GbiG C-terminal domain-like 92 c2ftcB_ not modelled 14.0 14 PDB header:ribosome Chain: B: PDB Molecule:mitochondrial ribosomal protein l2; PDBTitle: structural model for the large subunit of the mammalian mitochondrial2 ribosome 93 c1skqB_ not modelled 13.9 24 PDB header:translation Chain: B: PDB Molecule:elongation factor 1-alpha; PDBTitle: the crystal structure of sulfolobus solfataricus elongation2 factor 1-alpha in complex with magnesium and gdp 94 d2g50a3 not modelled 13.7 13 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:Pyruvate kinase, C-terminal domain 95 d1lnsa2 not modelled 13.5 10 Fold:Galactose-binding domain-like Superfamily:Galactose-binding domain-like Family:PepX C-terminal domain-like 96 d2evra2 not modelled 13.4 8 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:NlpC/P60 97 c2qptA_ not modelled 13.3 24 PDB header:endocytosis Chain: A: PDB Molecule:eh domain-containing protein-2; PDBTitle: crystal structure of an ehd atpase involved in membrane remodelling 98 c3simA_ not modelled 13.0 18 PDB header:hydrolase Chain: A: PDB Molecule:protein, family 18 chitinase; PDBTitle: crystallographic structure analysis of family 18 chitinase from crocus2 vernus 99 c2d6fA_ not modelled 13.0 21 PDB header:ligase/rna Chain: A: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: crystal structure of glu-trna(gln) amidotransferase in the2 complex with trna(gln)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0