Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	Y	R	I	I	P	V	T	A	F	S	Q	N	C	S	L	I	W	C	E	Q	T	R	L	A	A	L	V	D	P	G	G	D	A	E	K	I	K	Q	E	V	D	D	S	G	L	T	L	M	Q	I	L	L	T	H	G	H	L	D
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		H	V	G	A	A	A	E	L	A	Q	H	Y	G	V	P	V	F	G	P	E	K	E	D	E	F	W	L	Q	G	L	P	A	Q	S	R	M	F	G	L	E	E	C	Q	P	L	T	P	D	R	W	L	N	E	G	D	T	I	S	I	G
Secondary structure
SS confidence
Disorder																																?	?	?	?		?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	V	T	L	Q	V	L	H	C	P	G	H	T	P	G	H	V	V	F	F	D	D	R	A	K	L	L	I	S	G	D	V	I	F	K	G	G	V	G	R	S	D	F	P	R	G	D	H	N	Q	L	I	S	S	I	K	D	K	L	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.
Sequence		P	L	G	D	D	V	I	F	I	P	G	H	G	P	L	S	T	L	G	Y	E	R	L	H	N	P	F	L	Q	D	E	M	P	V	W
Secondary structure
SS confidence
Disorder																																?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2xf4 chain A Region: 1 - 210 Aligned: 210 Modelled: 210 Confidence: 100.0% Identity: 91% PDB header:hydrolase Chain: A: PDB Molecule:hydroxyacylglutathione hydrolase; PDBTitle: crystal structure of salmonella enterica serovar2 typhimurium ycbl Phyre2 PDB 3r2u chain C Region: 1 - 214 Aligned: 200 Modelled: 201 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: C: PDB Molecule:metallo-beta-lactamase family protein; PDBTitle: 2.1 angstrom resolution crystal structure of metallo-beta-lactamase2 from staphylococcus aureus subsp. aureus col Phyre2 PDB 3tp9 chain B Region: 1 - 209 Aligned: 196 Modelled: 196 Confidence: 100.0% Identity: 37% PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase and rhodanese domain protein; PDBTitle: crystal structure of alicyclobacillus acidocaldarius protein with2 beta-lactamase and rhodanese domains Phyre2 PDB 1qh5 chain A Region: 1 - 209 Aligned: 183 Modelled: 188 Confidence: 100.0% Identity: 31% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Glyoxalase II (hydroxyacylglutathione hydrolase) Phyre2 PDB 1xm8 chain A Region: 1 - 209 Aligned: 185 Modelled: 191 Confidence: 100.0% Identity: 32% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Glyoxalase II (hydroxyacylglutathione hydrolase) Phyre2 PDB 2zwr chain A Region: 1 - 208 Aligned: 200 Modelled: 208 Confidence: 100.0% Identity: 36% PDB header:hydrolase Chain: A: PDB Molecule:metallo-beta-lactamase superfamily protein; PDBTitle: crystal structure of ttha1623 from thermus thermophilus hb8 Phyre2 PDB 2qed chain A domain 1 Region: 1 - 214 Aligned: 186 Modelled: 192 Confidence: 100.0% Identity: 35% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Glyoxalase II (hydroxyacylglutathione hydrolase) Phyre2 PDB 2p18 chain A Region: 3 - 214 Aligned: 197 Modelled: 197 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:glyoxalase ii; PDBTitle: crystal structure of the leishmania infantum glyoxalase ii Phyre2 PDB 2gcu chain D Region: 1 - 214 Aligned: 194 Modelled: 194 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: D: PDB Molecule:putative hydroxyacylglutathione hydrolase 3; PDBTitle: x-ray structure of gene product from arabidopsis thaliana2 at1g53580 Phyre2 PDB 2q0i chain A domain 1 Region: 5 - 211 Aligned: 205 Modelled: 207 Confidence: 100.0% Identity: 24% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: PqsE-like Phyre2 PDB 2gmn chain A domain 1 Region: 5 - 204 Aligned: 196 Modelled: 200 Confidence: 100.0% Identity: 22% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 PDB 3lvz chain A Region: 5 - 204 Aligned: 196 Modelled: 200 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:blr6230 protein; PDBTitle: new refinement of the crystal structure of bjp-1, a subclass b32 metallo-beta-lactamase of bradyrhizobium japonicum Phyre2 PDB 1jjt chain A Region: 7 - 212 Aligned: 188 Modelled: 206 Confidence: 100.0% Identity: 19% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 PDB 3l6n chain A Region: 3 - 210 Aligned: 192 Modelled: 195 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:metallo-beta-lactamase; PDBTitle: crystal structure of metallo-beta-lactamase ind-7 Phyre2 PDB 1ko3 chain A Region: 9 - 209 Aligned: 188 Modelled: 201 Confidence: 100.0% Identity: 20% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 PDB 3rkj chain A Region: 9 - 212 Aligned: 195 Modelled: 204 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase ndm-1; PDBTitle: crystal structure of new delhi metallo-beta-lactamase-1 from2 klebsiella pnueumoniae Phyre2 PDB 3spu chain B Region: 9 - 210 Aligned: 193 Modelled: 202 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase ndm-1; PDBTitle: apo ndm-1 crystal structure Phyre2 PDB 2aio chain A domain 1 Region: 5 - 197 Aligned: 189 Modelled: 193 Confidence: 100.0% Identity: 22% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 PDB 2zo4 chain A Region: 3 - 204 Aligned: 197 Modelled: 202 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:metallo-beta-lactamase family protein; PDBTitle: crystal structure of metallo-beta-lactamase family protein ttha14292 from thermus thermophilus hb8 Phyre2 PDB 1m2x chain A Region: 3 - 210 Aligned: 192 Modelled: 208 Confidence: 100.0% Identity: 16% Fold: Metallo-hydrolase/oxidoreductase Superfamily: Metallo-hydrolase/oxidoreductase Family: Zn metallo-beta-lactamase Phyre2 1 c2xf4A_ 2 c3r2uC_ 3 c3tp9B_ 4 d1qh5a_ 5 d1xm8a_ 6 c2zwrA_ 7 d2qeda1 8 c2p18A_ 9 c2gcuD_ 10 d2q0ia1 11 d2gmna1 12 c3lvzA_ 13 d1jjta_ 14 c3l6nA_ 15 d1ko3a_ 16 c3rkjA_ 17 c3spuB_ 18 d2aioa1 19 c2zo4A_ 20 d1m2xa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2xf4A_ 100.0 91 PDB header:hydrolase Chain: A: PDB Molecule:hydroxyacylglutathione hydrolase; PDBTitle: crystal structure of salmonella enterica serovar2 typhimurium ycbl 2 c3r2uC_ 100.0 33 PDB header:hydrolase Chain: C: PDB Molecule:metallo-beta-lactamase family protein; PDBTitle: 2.1 angstrom resolution crystal structure of metallo-beta-lactamase2 from staphylococcus aureus subsp. aureus col 3 c3tp9B_ 100.0 37 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase and rhodanese domain protein; PDBTitle: crystal structure of alicyclobacillus acidocaldarius protein with2 beta-lactamase and rhodanese domains 4 d1qh5a_ 100.0 31 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Glyoxalase II (hydroxyacylglutathione hydrolase) 5 d1xm8a_ 100.0 32 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Glyoxalase II (hydroxyacylglutathione hydrolase) 6 c2zwrA_ 100.0 36 PDB header:hydrolase Chain: A: PDB Molecule:metallo-beta-lactamase superfamily protein; PDBTitle: crystal structure of ttha1623 from thermus thermophilus hb8 7 d2qeda1 100.0 35 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Glyoxalase II (hydroxyacylglutathione hydrolase) 8 c2p18A_ 100.0 27 PDB header:hydrolase Chain: A: PDB Molecule:glyoxalase ii; PDBTitle: crystal structure of the leishmania infantum glyoxalase ii 9 c2gcuD_ 100.0 30 PDB header:hydrolase Chain: D: PDB Molecule:putative hydroxyacylglutathione hydrolase 3; PDBTitle: x-ray structure of gene product from arabidopsis thaliana2 at1g53580 10 d2q0ia1 100.0 24 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:PqsE-like 11 d2gmna1 100.0 22 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 12 c3lvzA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:blr6230 protein; PDBTitle: new refinement of the crystal structure of bjp-1, a subclass b32 metallo-beta-lactamase of bradyrhizobium japonicum 13 d1jjta_ 100.0 19 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 14 c3l6nA_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:metallo-beta-lactamase; PDBTitle: crystal structure of metallo-beta-lactamase ind-7 15 d1ko3a_ 100.0 20 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 16 c3rkjA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase ndm-1; PDBTitle: crystal structure of new delhi metallo-beta-lactamase-1 from2 klebsiella pnueumoniae 17 c3spuB_ 100.0 15 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase ndm-1; PDBTitle: apo ndm-1 crystal structure 18 d2aioa1 100.0 22 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 19 c2zo4A_ 100.0 26 PDB header:hydrolase Chain: A: PDB Molecule:metallo-beta-lactamase family protein; PDBTitle: crystal structure of metallo-beta-lactamase family protein ttha14292 from thermus thermophilus hb8 20 d1m2xa_ 100.0 16 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 21 d1k07a_ not modelled 100.0 20 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 22 c2q9uB_ not modelled 100.0 15 PDB header:oxidoreductase Chain: B: PDB Molecule:a-type flavoprotein; PDBTitle: crystal structure of the flavodiiron protein from giardia2 intestinalis 23 d1znba_ not modelled 100.0 18 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 24 d1mqoa_ not modelled 100.0 19 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 25 c2ohiB_ not modelled 100.0 22 PDB header:oxidoreductase Chain: B: PDB Molecule:type a flavoprotein fpra; PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state 26 c2yz3B_ not modelled 100.0 17 PDB header:hydrolase Chain: B: PDB Molecule:metallo-beta-lactamase; PDBTitle: crystallographic investigation of inhibition mode of the2 vim-2 metallo-beta-lactamase from pseudomonas aeruginosa3 with mercaptocarboxylate inhibitor 27 c3adrA_ not modelled 99.9 21 PDB header:signaling protein Chain: A: PDB Molecule:putative uncharacterized protein st1585; PDBTitle: the first crystal structure of an archaeal metallo-beta-lactamase2 superfamily protein; st1585 from sulfolobus tokodaii 28 c1ychD_ not modelled 99.9 19 PDB header:oxidoreductase Chain: D: PDB Molecule:nitric oxide reductase; PDBTitle: x-ray crystal structures of moorella thermoacetica fpra.2 novel diiron site structure and mechanistic insights into3 a scavenging nitric oxide reductase 29 d1x8ha_ not modelled 99.9 14 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase 30 c1e5dA_ not modelled 99.9 20 PDB header:oxidoreductase Chain: A: PDB Molecule:rubredoxin\:oxygen oxidoreductase; PDBTitle: rubredoxin oxygen:oxidoreductase (roo) from anaerobe2 desulfovibrio gigas 31 c1vmeB_ not modelled 99.9 21 PDB header:electron transport Chain: B: PDB Molecule:flavoprotein; PDBTitle: crystal structure of flavoprotein (tm0755) from thermotoga maritima at2 1.80 a resolution 32 c2cfuA_ not modelled 99.9 21 PDB header:hydrolase Chain: A: PDB Molecule:sdsa1; PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid. 33 c3hnnD_ not modelled 99.9 16 PDB header:oxidoreductase Chain: D: PDB Molecule:putative diflavin flavoprotein a 5; PDBTitle: crystal structure of putative diflavin flavoprotein a 5 (fragment 1-2 254) from nostoc sp. pcc 7120, northeast structural genomics3 consortium target nsr435a 34 d2cfua2 not modelled 99.9 18 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Alkylsulfatase-like 35 c2fhxB_ not modelled 99.9 18 PDB header:hydrolase, metal binding protein Chain: B: PDB Molecule:spm-1; PDBTitle: pseudomonas aeruginosa spm-1 metallo-beta-lactamase 36 c3eshB_ not modelled 99.9 17 PDB header:hydrolase Chain: B: PDB Molecule:protein similar to metal-dependent hydrolase; PDBTitle: crystal structure of a probable metal-dependent hydrolase2 from staphylococcus aureus. northeast structural genomics3 target zr314 37 d1ycga2 not modelled 99.9 18 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:ROO N-terminal domain-like 38 c3aj3A_ not modelled 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:4-pyridoxolactonase; PDBTitle: crystal structure of selenomethionine substituted 4-pyridoxolactonase2 from mesorhizobium loti 39 d2p97a1 not modelled 99.9 19 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Ava3068-like 40 d1e5da2 not modelled 99.9 19 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:ROO N-terminal domain-like 41 d1vmea2 not modelled 99.9 19 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:ROO N-terminal domain-like 42 c2r2dC_ not modelled 99.9 16 PDB header:hydrolase Chain: C: PDB Molecule:zn-dependent hydrolases; PDBTitle: structure of a quorum-quenching lactonase (aiib) from agrobacterium2 tumefaciens 43 c3sd9B_ not modelled 99.9 13 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of serratia fonticola sfh-i: source of the2 nucleophile in the catalytic mechanism of mono-zinc metallo-beta-3 lactamases 44 c1p9eA_ not modelled 99.9 22 PDB header:hydrolase Chain: A: PDB Molecule:methyl parathion hydrolase; PDBTitle: crystal structure analysis of methyl parathion hydrolase from2 pseudomonas sp wbc-3 45 d1p9ea_ not modelled 99.9 22 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Methyl parathion hydrolase 46 c2bibA_ not modelled 99.8 18 PDB header:hydrolase Chain: A: PDB Molecule:teichoic acid phosphorylcholine esterase/ choline binding PDBTitle: crystal structure of the complete modular teichioic acid2 phosphorylcholine esterase pce (cbpe) from streptococcus3 pneumoniae 47 c2br6A_ not modelled 99.8 21 PDB header:hydrolase Chain: A: PDB Molecule:aiia-like protein; PDBTitle: crystal structure of quorum-quenching n-acyl homoserine2 lactone lactonase 48 c3zq4C_ not modelled 99.8 16 PDB header:hydrolase Chain: C: PDB Molecule:ribonuclease j 1; PDBTitle: unusual, dual endo- and exo-nuclease activity in the degradosome2 explained by crystal structure analysis of rnase j1 49 d1ztca1 not modelled 99.8 17 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:TM0894-like 50 c2p4zA_ not modelled 99.8 18 PDB header:hydrolase Chain: A: PDB Molecule:metal-dependent hydrolases of the beta-lactamase PDBTitle: a ferredoxin-like metallo-beta-lactamase superfamily protein from2 thermoanaerobacter tengcongensis 51 d1wraa1 not modelled 99.8 23 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Pce catalytic domain-like 52 c3bk2A_ not modelled 99.7 18 PDB header:hydrolase Chain: A: PDB Molecule:metal dependent hydrolase; PDBTitle: crystal structure analysis of the rnase j/ump complex 53 d2i7ta1 not modelled 99.7 20 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:beta-CASP RNA-metabolising hydrolases 54 c3af5A_ not modelled 99.6 21 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein ph1404; PDBTitle: the crystal structure of an archaeal cpsf subunit, ph1404 from2 pyrococcus horikoshii 55 c2ycbA_ not modelled 99.6 23 PDB header:hydrolase Chain: A: PDB Molecule:cleavage and polyadenylation specificity factor; PDBTitle: structure of the archaeal beta-casp protein with n-terminal2 kh domains from methanothermobacter thermautotrophicus 56 d2dkfa1 not modelled 99.6 27 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:beta-CASP RNA-metabolising hydrolases 57 c2az4A_ not modelled 99.6 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ef2904; PDBTitle: crystal structure of a protein of unknown function from enterococcus2 faecalis v583 58 c2xr1A_ not modelled 99.6 19 PDB header:hydrolase Chain: A: PDB Molecule:cleavage and polyadenylation specificity factor 100 kd PDBTitle: dimeric archaeal cleavage and polyadenylation specificity2 factor with n-terminal kh domains (kh-cpsf) from methanosarcina3 mazei 59 c3h3eA_ not modelled 99.6 16 PDB header:structural genomics, metal binding prote Chain: A: PDB Molecule:uncharacterized protein tm1679; PDBTitle: crystal structure of tm1679, a metal-dependent hydrolase of2 the beta-lactamase superfamily 60 c2xr1B_ not modelled 99.5 19 PDB header:hydrolase Chain: B: PDB Molecule:cleavage and polyadenylation specificity factor 100 kd PDBTitle: dimeric archaeal cleavage and polyadenylation specificity2 factor with n-terminal kh domains (kh-cpsf) from methanosarcina3 mazei 61 d2i7xa1 not modelled 99.5 17 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:beta-CASP RNA-metabolising hydrolases 62 c2i7xA_ not modelled 99.5 17 PDB header:rna binding protein, protein binding Chain: A: PDB Molecule:protein cft2; PDBTitle: structure of yeast cpsf-100 (ydh1p) 63 c3md7A_ not modelled 99.5 14 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase-like; PDBTitle: crystal structure of a beta-lactamase-like protein bound to gmp from2 brucella melitensis 64 c3zwfA_ not modelled 99.5 17 PDB header:hydrolase Chain: A: PDB Molecule:zinc phosphodiesterase elac protein 1; PDBTitle: crystal structure of human trnase z, short form (elac1). 65 c1zkpD_ not modelled 99.4 15 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein ba1088; PDBTitle: 1.5a resolution crystal structure of a metallo beta lactamase family2 protein, the elac homolgue of bacillus anthracis, a putative3 ribonuclease 66 c3g1pA_ not modelled 99.4 15 PDB header:lyase Chain: A: PDB Molecule:protein phnp; PDBTitle: crystals structure of phnp from e.coli k-12 67 d1xtoa_ not modelled 99.3 13 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Coenzyme PQQ synthesis protein B, PqqB 68 d2az4a1 not modelled 99.3 16 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:beta-CASP RNA-metabolising hydrolases 69 c3kl7A_ not modelled 99.3 19 PDB header:hydrolase Chain: A: PDB Molecule:putative metal-dependent hydrolase; PDBTitle: crystal structure of putative metal-dependent hydrolase2 (yp_001302908.1) from parabacteroides distasonis atcc 8503 at 2.30 a3 resolution 70 d1y44a1 not modelled 99.2 21 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:RNase Z-like 71 d1zkpa1 not modelled 99.2 16 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:YhfI-like 72 d2cbna1 not modelled 99.2 16 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:RNase Z-like 73 d2e7ya1 not modelled 98.8 20 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:RNase Z-like 74 c3bv6D_ not modelled 98.7 21 PDB header:hydrolase Chain: D: PDB Molecule:metal-dependent hydrolase; PDBTitle: crystal structure of uncharacterized metallo protein from vibrio2 cholerae with beta-lactamase like fold 75 c2wylF_ not modelled 98.7 21 PDB header:hydrolase Chain: F: PDB Molecule:l-ascorbate-6-phosphate lactonase ulag; PDBTitle: apo structure of a metallo-b-lactamase 76 c3rpcD_ not modelled 98.6 23 PDB header:hydrolase Chain: D: PDB Molecule:possible metal-dependent hydrolase; PDBTitle: the crystal structure of a possible metal-dependent hydrolase from2 veillonella parvula dsm 2008 77 d1vjna_ not modelled 98.4 22 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Hypothetical protein TM0207 78 c3lpnB_ not modelled 83.8 25 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of the phosphoribosylpyrophosphate (prpp) synthetase2 from thermoplasma volcanium in complex with an atp analog (ampcpp). 79 c3efhB_ not modelled 81.9 39 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1 80 d1u9ya2 not modelled 81.6 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 81 c1dkrB_ not modelled 80.4 25 PDB header:transferase Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase; PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation. 82 d1dkua2 not modelled 80.1 25 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 83 c3dahB_ not modelled 77.2 26 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: 2.3 a crystal structure of ribose-phosphate pyrophosphokinase from2 burkholderia pseudomallei 84 c1u9yD_ not modelled 76.7 22 PDB header:transferase Chain: D: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of phosphoribosyl diphosphate synthase2 from methanocaldococcus jannaschii 85 d2c4ka2 not modelled 76.6 28 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 86 c2c4kD_ not modelled 75.2 24 PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39) 87 d1gph11 not modelled 56.9 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 88 d1ecfa1 not modelled 56.2 24 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 89 d1zn7a1 not modelled 56.1 14 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 90 d1o57a2 not modelled 48.3 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 91 c2dy0A_ not modelled 46.5 20 PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli 92 c2wnsB_ not modelled 46.2 12 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp) 93 c3mjdA_ not modelled 46.2 15 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.9 angstrom crystal structure of orotate2 phosphoribosyltransferase (pyre) francisella tularensis. 94 c3dmpD_ not modelled 46.0 16 PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: 2.6 a crystal structure of uracil phosphoribosyltransferase2 from burkholderia pseudomallei 95 d1l1qa_ not modelled 45.4 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 96 d1ii7a_ not modelled 44.6 22 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DNA double-strand break repair nuclease 97 c2yzkC_ not modelled 44.6 24 PDB header:transferase Chain: C: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 aeropyrum pernix 98 c3dezA_ not modelled 44.2 12 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 streptococcus mutans 99 d1g2qa_ not modelled 43.6 24 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 100 d1mzva_ not modelled 43.6 29 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 101 d1lh0a_ not modelled 43.4 24 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 102 d1vcha1 not modelled 43.2 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 103 d2aeea1 not modelled 42.4 12 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 104 c3rl4A_ not modelled 41.1 23 PDB header:hydrolase Chain: A: PDB Molecule:metallophosphoesterase mpped2; PDBTitle: rat metallophosphodiesterase mpped2 g252h mutant 105 c2p1zA_ not modelled 38.1 12 PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase; PDBTitle: crystal structure of phosphoribosyltransferase from corynebacterium2 diphtheriae 106 c3m3hA_ not modelled 36.7 24 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.75 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase from bacillus anthracis str. 'ames3 ancestor' 107 c1o57A_ not modelled 36.1 18 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 108 c2przB_ not modelled 35.8 9 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase 1; PDBTitle: s. cerevisiae orotate phosphoribosyltransferase complexed2 with omp 109 d1bd3a_ not modelled 35.3 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 110 d1y0ba1 not modelled 35.0 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 111 c3ib7A_ not modelled 34.6 20 PDB header:hydrolase Chain: A: PDB Molecule:icc protein; PDBTitle: crystal structure of full length rv0805 112 c3n2lA_ not modelled 31.9 22 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 2.1 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase (pyre) from vibrio cholerae o1 biovar eltor3 str. n16961 113 d1dj3a_ not modelled 30.8 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 114 d1dj2a_ not modelled 30.6 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 115 d1uf3a_ not modelled 28.5 13 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like 116 c1ecjB_ not modelled 27.7 24 PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer 117 d1qb7a_ not modelled 26.8 26 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 118 d1vdma1 not modelled 26.4 29 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 119 c1gph1_ not modelled 25.6 21 PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis 120 d1yfza1 not modelled 22.4 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)

Binding site prediction

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If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0