Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP24181
DateThu Jan 5 11:40:58 GMT 2012
Unique Job ID44c9a2357485fc67

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1oy8A_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
Confidence and coverage
Confidence:100.0% Coverage: 97%
1004 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT
Secondary structure 
SS confidence 
Disorder  ??
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ
Secondary structure 
SS confidence 
Disorder 
?????
????
????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA
Secondary structure 
SS confidence 
Disorder 
?
?
??????
?
??
?
???
?
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF
Secondary structure 
SS confidence 
Disorder 
?
????????
???????????
??
??
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL
Secondary structure 
SS confidence 
Disorder 
?
???
???
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL
Secondary structure 
SS confidence 
Disorder 
????
?
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY
Secondary structure 
SS confidence 
Disorder 
????????????
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN
Secondary structure 
SS confidence 
Disorder 
???
??
?
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG
Secondary structure 
SS confidence 
Disorder 
????????????
?????
????
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL
Secondary structure 
SS confidence 
Disorder  ?
???????????????
?
???
?
??????
Disorder confidence 
 
   .........730.........740.........750.........760.........770.........780
Sequence  EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM
Secondary structure 
SS confidence 
Disorder  ?
?
?
??
Disorder confidence 
 
   .........790.........800.........810.........820.........830.........840
Sequence  LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM
Secondary structure 
SS confidence 
Disorder  ??
?
?
?
??
?
??????
???
??????
Disorder confidence 
 
   .........850.........860.........870.........880.........890.........900
Sequence  ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........910.........920.........930.........940.........950.........960
Sequence  MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........970.........980.........990.........1000.........1010.........1020
Sequence  EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........1030....
Sequence  VPVFFVVIRRCFKG
Secondary structure 
SS confidence 
Disorder 
???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1oy8 chain A

3D model

Region: 7 - 1033
Aligned: 1004
Modelled: 1027
Confidence: 100.0%
Identity: 78%
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump

Phyre2

PDB 3k07 chain A

3D model

Region: 1 - 1029
Aligned: 1000
Modelled: 1009
Confidence: 100.0%
Identity: 21%
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa

Phyre2

PDB 3aqp chain B

3D model

Region: 86 - 1031
Aligned: 675
Modelled: 715
Confidence: 100.0%
Identity: 17%
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus

Phyre2

PDB 1iwg chain A domain 8

3D model

Region: 836 - 1033
Aligned: 198
Modelled: 198
Confidence: 100.0%
Identity: 73%
Fold: Multidrug efflux transporter AcrB transmembrane domain
Superfamily: Multidrug efflux transporter AcrB transmembrane domain
Family: Multidrug efflux transporter AcrB transmembrane domain

Phyre2

PDB 1iwg chain A domain 7

3D model

Region: 304 - 498
Aligned: 195
Modelled: 195
Confidence: 100.0%
Identity: 82%
Fold: Multidrug efflux transporter AcrB transmembrane domain
Superfamily: Multidrug efflux transporter AcrB transmembrane domain
Family: Multidrug efflux transporter AcrB transmembrane domain

Phyre2

PDB 1iwg chain A domain 1

3D model

Region: 38 - 134
Aligned: 97
Modelled: 97
Confidence: 99.9%
Identity: 88%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 1iwg chain A domain 2

3D model

Region: 232 - 330
Aligned: 98
Modelled: 99
Confidence: 99.7%
Identity: 49%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 1iwg chain A domain 5

3D model

Region: 182 - 273
Aligned: 92
Modelled: 92
Confidence: 99.7%
Identity: 68%
Fold: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains

Phyre2

PDB 1iwg chain A domain 6

3D model

Region: 724 - 811
Aligned: 88
Modelled: 88
Confidence: 99.2%
Identity: 67%
Fold: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family: Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains

Phyre2

PDB 1iwg chain A domain 3

3D model

Region: 566 - 672
Aligned: 107
Modelled: 107
Confidence: 98.9%
Identity: 65%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 1iwg chain A domain 4

3D model

Region: 673 - 858
Aligned: 97
Modelled: 98
Confidence: 98.0%
Identity: 85%
Fold: Ferredoxin-like
Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Phyre2

PDB 2rop chain A

3D model

Region: 62 - 209
Aligned: 119
Modelled: 148
Confidence: 96.3%
Identity: 12%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of domains 3 and 4 of human atp7b

Phyre2

PDB 2ew9 chain A

3D model

Region: 62 - 209
Aligned: 121
Modelled: 148
Confidence: 95.8%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of apowln5-6

Phyre2

PDB 1s6u chain A

3D model

Region: 159 - 222
Aligned: 59
Modelled: 64
Confidence: 91.3%
Identity: 15%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 2qif chain A domain 1

3D model

Region: 159 - 215
Aligned: 52
Modelled: 57
Confidence: 91.3%
Identity: 21%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 2aw0 chain A

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 91.0%
Identity: 17%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 2kkh chain A

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 90.3%
Identity: 15%
PDB header:metal transport
Chain: A: PDB Molecule:putative heavy metal transporter;
PDBTitle: structure of the zinc binding domain of the atpase hma4

Phyre2

PDB 2rml chain A

3D model

Region: 62 - 214
Aligned: 118
Modelled: 130
Confidence: 90.2%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting p-type atpase copa;
PDBTitle: solution structure of the n-terminal soluble domains of2 bacillus subtilis copa

Phyre2

PDB 1p6t chain A domain 2

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 89.4%
Identity: 13%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2

PDB 1p6t chain A domain 1

3D model

Region: 159 - 209
Aligned: 46
Modelled: 51
Confidence: 89.4%
Identity: 17%
Fold: Ferredoxin-like
Superfamily: HMA, heavy metal-associated domain
Family: HMA, heavy metal-associated domain

Phyre2
1
c1oy8A_
2
c3k07A_
3
c3aqpB_
4
d1iwga8
5
d1iwga7
6
d1iwga1
7
d1iwga2
8
d1iwga5
9
d1iwga6
10
d1iwga3
11
d1iwga4
12
c2ropA_
13
c2ew9A_
14
d1s6ua_
15
d2qifa1
16
d2aw0a_
17
c2kkhA_
18
c2rmlA_
19
d1p6ta2
20
d1p6ta1
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1oy8A_
100.0 78 PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
2c3k07A_
100.0 21 PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
3c3aqpB_
100.0 17 PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
4d1iwga8
100.0 73 Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
5d1iwga7
100.0 82 Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
6d1iwga1
99.9 88 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
7d1iwga2
99.7 49 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
8d1iwga5
99.7 68 Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
9d1iwga6
99.2 67 Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
10d1iwga3
98.9 65 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
11d1iwga4
98.0 85 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
12c2ropA_
96.3 12 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of domains 3 and 4 of human atp7b
13c2ew9A_
95.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 2;
PDBTitle: solution structure of apowln5-6
14d1s6ua_
91.3 15 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
15d2qifa1
91.3 21 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
16d2aw0a_
91.0 17 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
17c2kkhA_
90.3 15 PDB header:metal transport
Chain: A: PDB Molecule:putative heavy metal transporter;
PDBTitle: structure of the zinc binding domain of the atpase hma4
18c2rmlA_
90.2 14 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting p-type atpase copa;
PDBTitle: solution structure of the n-terminal soluble domains of2 bacillus subtilis copa
19d1p6ta2
89.4 13 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
20d1p6ta1
89.4 17 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
21c3dxsX_
not modelled 89.1 17 PDB header:hydrolase
Chain: X: PDB Molecule:copper-transporting atpase ran1;
PDBTitle: crystal structure of a copper binding domain from hma7, a p-2 type atpase
22d1cpza_
not modelled 89.1 11 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
23d1kvja_
not modelled 88.5 20 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
24c2ga7A_
not modelled 88.4 22 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the copper(i) form of the third metal-2 binding domain of atp7a protein (menkes disease protein)
25d1q8la_
not modelled 88.1 12 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
26c2l3mA_
not modelled 88.0 21 PDB header:metal binding protein
Chain: A: PDB Molecule:copper-ion-binding protein;
PDBTitle: solution structure of the putative copper-ion-binding protein from2 bacillus anthracis str. ames
27c2ldiA_
not modelled 87.7 19 PDB header:hydrolase
Chain: A: PDB Molecule:zinc-transporting atpase;
PDBTitle: nmr solution structure of ziaan sub mutant
28c1yjrA_
not modelled 87.4 16 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the apo form of the sixth soluble2 domain a69p mutant of menkes protein
29c2ofhX_
not modelled 87.1 15 PDB header:hydrolase, membrane protein
Chain: X: PDB Molecule:zinc-transporting atpase;
PDBTitle: solution structure of the n-terminal domain of the zinc(ii) atpase2 ziaa in its apo form
30d1afia_
not modelled 86.9 20 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
31c1yg0A_
not modelled 86.1 12 PDB header:metal transport
Chain: A: PDB Molecule:cop associated protein;
PDBTitle: solution structure of apo-copp from helicobacter pylori
32c2kt2A_
not modelled 86.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:mercuric reductase;
PDBTitle: structure of nmera, the n-terminal hma domain of tn501 mercuric2 reductase
33d1osda_
not modelled 85.8 18 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
34c1y3kA_
not modelled 83.8 10 PDB header:hydrolase
Chain: A: PDB Molecule:copper-transporting atpase 1;
PDBTitle: solution structure of the apo form of the fifth domain of2 menkes protein
35c2k2pA_
not modelled 77.7 9 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein atu1203;
PDBTitle: solution nmr structure of protein atu1203 from agrobacterium2 tumefaciens. northeast structural genomics consortium (nesg) target3 att10, ontario center for structural proteomics target atc1183
36d1qupa2
not modelled 77.3 19 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
37d2ggpb1
not modelled 76.4 15 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
38c1jk9D_
not modelled 73.7 19 PDB header:oxidoreductase
Chain: D: PDB Molecule:copper chaperone for superoxide dismutase;
PDBTitle: heterodimer between h48f-ysod1 and yccs
39d1mwza_
not modelled 73.6 27 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
40d1sb6a_
not modelled 73.5 13 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
41c2gcfA_
not modelled 72.5 18 PDB header:hydrolase
Chain: A: PDB Molecule:cation-transporting atpase pacs;
PDBTitle: solution structure of the n-terminal domain of the coppper(i) atpase2 pacs in its apo form
42d1cc8a_
not modelled 70.0 13 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
43c2rogA_
not modelled 68.6 14 PDB header:metal binding protein
Chain: A: PDB Molecule:heavy metal binding protein;
PDBTitle: solution structure of thermus thermophilus hb8 ttha17182 protein in living e. coli cells
44c2aj1A_
not modelled 68.1 13 PDB header:hydrolase
Chain: A: PDB Molecule:probable cadmium-transporting atpase;
PDBTitle: solution structure of apocada
45c2crlA_
not modelled 66.8 21 PDB header:chaperone
Chain: A: PDB Molecule:copper chaperone for superoxide dismutase;
PDBTitle: the apo form of hma domain of copper chaperone for2 superoxide dismutase
46c3j09A_
not modelled 65.9 15 PDB header:hydrolase, metal transport
Chain: A: PDB Molecule:copper-exporting p-type atpase a;
PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa
47c1qupA_
not modelled 65.6 19 PDB header:chaperone
Chain: A: PDB Molecule:superoxide dismutase 1 copper chaperone;
PDBTitle: crystal structure of the copper chaperone for superoxide2 dismutase
48c2yvxD_
not modelled 61.9 12 PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
49d2cu6a1
not modelled 55.8 25 Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:PaaD-like
50d1uwda_
not modelled 53.9 14 Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:PaaD-like
51c1yj7A_
not modelled 49.8 16 PDB header:protein transport
Chain: A: PDB Molecule:escj;
PDBTitle: crystal structure of enteropathogenic e.coli (epec) type iii secretion2 system protein escj
52c2kyzA_
not modelled 39.9 13 PDB header:metal binding protein
Chain: A: PDB Molecule:heavy metal binding protein;
PDBTitle: nmr structure of heavy metal binding protein tm0320 from thermotoga2 maritima
53d2vv5a2
not modelled 38.3 14 Fold:Ferredoxin-like
Superfamily:Mechanosensitive channel protein MscS (YggB), C-terminal domain
Family:Mechanosensitive channel protein MscS (YggB), C-terminal domain
54c2yy3B_
not modelled 32.3 12 PDB header:translation
Chain: B: PDB Molecule:elongation factor 1-beta;
PDBTitle: crystal structure of translation elongation factor ef-1 beta from2 pyrococcus horikoshii
55c3c6fD_
not modelled 29.7 8 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:yetf protein;
PDBTitle: crystal structure of protein bsu07140 from bacillus subtilis
56c1ciiA_
not modelled 26.4 17 PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
57c1vs3B_
not modelled 25.0 21 PDB header:isomerase
Chain: B: PDB Molecule:trna pseudouridine synthase a;
PDBTitle: crystal structure of the trna pseudouridine synthase trua from thermus2 thermophilus hb8
58c3lnoA_
not modelled 23.9 15 PDB header:unknown function
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of domain of unknown function duf59 from2 bacillus anthracis
59c3fryB_
not modelled 21.1 15 PDB header:hydrolase
Chain: B: PDB Molecule:probable copper-exporting p-type atpase a;
PDBTitle: crystal structure of the copa c-terminal metal binding domain
60d2nwwa1
not modelled 20.9 7 Fold:Proton glutamate symport protein
Superfamily:Proton glutamate symport protein
Family:Proton glutamate symport protein
61c2k9yB_
not modelled 19.6 21 PDB header:transferase
Chain: B: PDB Molecule:ephrin type-a receptor 2;
PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0
62c2k9yA_
not modelled 19.6 21 PDB header:transferase
Chain: A: PDB Molecule:ephrin type-a receptor 2;
PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0
63c2mltA_
not modelled 18.0 23 PDB header:toxin (hemolytic polypeptide)
Chain: A: PDB Molecule:melittin;
PDBTitle: melittin
64c2mltB_
not modelled 18.0 23 PDB header:toxin (hemolytic polypeptide)
Chain: B: PDB Molecule:melittin;
PDBTitle: melittin
65c2hdiA_
not modelled 17.9 35 PDB header:protein transport,antimicrobial protein
Chain: A: PDB Molecule:colicin i receptor;
PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia.
66d1fe0a_
not modelled 16.6 19 Fold:Ferredoxin-like
Superfamily:HMA, heavy metal-associated domain
Family:HMA, heavy metal-associated domain
67c1bh1A_
not modelled 15.6 23 PDB header:toxin
Chain: A: PDB Molecule:melittin;
PDBTitle: structural studies of d-pro melittin, nmr, 20 structures
68d1jb0i_
not modelled 12.7 19 Fold:Single transmembrane helix
Superfamily:Subunit VIII of photosystem I reaction centre, PsaI
Family:Subunit VIII of photosystem I reaction centre, PsaI
69c1a87A_
not modelled 12.7 11 PDB header:bacteriocin
Chain: A: PDB Molecule:colicin n;
PDBTitle: colicin n
70d1a87a_
not modelled 12.7 11 Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
71c3lkxB_
not modelled 12.5 19 PDB header:chaperone
Chain: B: PDB Molecule:nascent polypeptide-associated complex subunit alpha;
PDBTitle: human nac dimerization domain
72d2gufa1
not modelled 12.0 30 Fold:Transmembrane beta-barrels
Superfamily:Porins
Family:Ligand-gated protein channel
73d2yvxa3
not modelled 12.0 9 Fold:MgtE membrane domain-like
Superfamily:MgtE membrane domain-like
Family:MgtE membrane domain-like
74d1f7ua3
not modelled 11.9 11 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Family:Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
75c2bbjB_
not modelled 11.0 11 PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter
76d1qmga1
not modelled 10.9 22 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
77d2b3ya2
not modelled 10.9 48 Fold:Aconitase iron-sulfur domain
Superfamily:Aconitase iron-sulfur domain
Family:Aconitase iron-sulfur domain
78c1f7uA_
not modelled 10.8 11 PDB header:ligase/rna
Chain: A: PDB Molecule:arginyl-trna synthetase;
PDBTitle: crystal structure of the arginyl-trna synthetase complexed with the2 trna(arg) and l-arg
79c2k1hA_
not modelled 10.7 9 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein ser13;
PDBTitle: solution nmr structure of ser13 from staphylococcus epidermidis.2 northeast structural genomics consortium target ser13
80d1xhja_
not modelled 10.6 13 Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:NifU C-terminal domain-like
81c2ki0A_
not modelled 10.6 13 PDB header:de novo protein
Chain: A: PDB Molecule:ds119;
PDBTitle: nmr structure of a de novo designed beta alpha beta
82c3ibwA_
not modelled 10.4 29 PDB header:transferase
Chain: A: PDB Molecule:gtp pyrophosphokinase;
PDBTitle: crystal structure of the act domain from gtp2 pyrophosphokinase of chlorobium tepidum. northeast3 structural genomics consortium target ctr148a
83d1ydxa2
not modelled 10.2 15 Fold:DNA methylase specificity domain
Superfamily:DNA methylase specificity domain
Family:Type I restriction modification DNA specificity domain
84c2e2xA_
not modelled 10.0 11 PDB header:signaling protein
Chain: A: PDB Molecule:neurofibromin;
PDBTitle: sec14 homology module of neurofibromin in complex with2 phosphatitylethanolamine
85c3g74B_
not modelled 9.9 33 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:protein of unknown function;
PDBTitle: crystal structure of a functionally unknown protein from eubacterium2 ventriosum atcc 27560
86c3gdzA_
not modelled 9.8 18 PDB header:ligase
Chain: A: PDB Molecule:arginyl-trna synthetase;
PDBTitle: crystal structure of arginyl-trna synthetase from klebsiella2 pneumoniae subsp. pneumoniae
87d2ffma1
not modelled 9.6 5 Fold:Hypothetical protein SAV1430
Superfamily:Hypothetical protein SAV1430
Family:Hypothetical protein SAV1430
88c3qlbA_
not modelled 9.6 20 PDB header:metal transport
Chain: A: PDB Molecule:enantio-pyochelin receptor;
PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin
89d1s7ba_
not modelled 9.6 16 Fold:Multidrug resistance efflux transporter EmrE
Superfamily:Multidrug resistance efflux transporter EmrE
Family:Multidrug resistance efflux transporter EmrE
90d2phcb2
not modelled 9.5 17 Fold:DCoH-like
Superfamily:PH0987 N-terminal domain-like
Family:PH0987 N-terminal domain-like
91c3g7sA_
not modelled 9.3 11 PDB header:ligase
Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1);
PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus
92d1ciia1
not modelled 9.2 15 Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
93c3iplB_
not modelled 8.9 10 PDB header:ligase
Chain: B: PDB Molecule:2-succinylbenzoate--coa ligase;
PDBTitle: crystal structure of o-succinylbenzoic acid-coa ligase from2 staphylococcus aureus subsp. aureus mu50
94d1cz5a1
not modelled 8.7 22 Fold:Double psi beta-barrel
Superfamily:ADC-like
Family:Cdc48 N-terminal domain-like
95d2cfxa2
not modelled 8.7 7 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
96c2jnvA_
not modelled 8.6 11 PDB header:metal transport
Chain: A: PDB Molecule:nifu-like protein 1, chloroplast;
PDBTitle: solution structure of c-terminal domain of nifu-like2 protein from oryza sativa
97d2cyya2
not modelled 8.2 4 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
98c2y9jt_
not modelled 8.2 16 PDB header:protein transport
Chain: T: PDB Molecule:protein prgh;
PDBTitle: three-dimensional model of salmonella's needle complex at2 subnanometer resolution
99d1dd5a_
not modelled 8.1 12 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:Ribosome recycling factor, RRF
Family:Ribosome recycling factor, RRF

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0