Email l.a.kelley@imperial.ac.uk Description P0A9X4 Date Thu Jan 5 11:11:37 GMT 2012 Unique Job ID 307825ae17c7bc1c

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1jcgA_ 100.0 54 PDB header:structural protein Chain: A: PDB Molecule:rod shape-determining protein mreb; PDBTitle: mreb from thermotoga maritima, amppnp 2 c2v7yA_ 100.0 26 PDB header:chaperone Chain: A: PDB Molecule:chaperone protein dnak; PDBTitle: crystal structure of the molecular chaperone dnak from2 geobacillus kaustophilus hta426 in post-atp hydrolysis3 state 3 c3d2fC_ 100.0 19 PDB header:chaperone Chain: C: PDB Molecule:heat shock protein homolog sse1; PDBTitle: crystal structure of a complex of sse1p and hsp70 4 c2khoA_ 100.0 21 PDB header:chaperone Chain: A: PDB Molecule:heat shock protein 70; PDBTitle: nmr-rdc / xray structure of e. coli hsp70 (dnak) chaperone2 (1-605) complexed with adp and substrate 5 c1dkgD_ 100.0 24 PDB header:complex (hsp24/hsp70) Chain: D: PDB Molecule:molecular chaperone dnak; PDBTitle: crystal structure of the nucleotide exchange factor grpe2 bound to the atpase domain of the molecular chaperone dnak 6 c3iucC_ 100.0 23 PDB header:chaperone Chain: C: PDB Molecule:heat shock 70kda protein 5 (glucose-regulated PDBTitle: crystal structure of the human 70kda heat shock protein 52 (bip/grp78) atpase domain in complex with adp 7 c2v7zA_ 100.0 24 PDB header:chaperone Chain: A: PDB Molecule:heat shock cognate 71 kda protein; PDBTitle: crystal structure of the 70-kda heat shock cognate protein2 from rattus norvegicus in post-atp hydrolysis state 8 c1hpmA_ 100.0 22 PDB header:hydrolase (acting on acid anhydrides) Chain: A: PDB Molecule:44k atpase fragment (n-terminal) of 7o kd heat- PDBTitle: how potassium affects the activity of the molecular2 chaperone hsc70. ii. potassium binds specifically in the3 atpase active site 9 c1o1f4_ 100.0 15 PDB header:contractile protein Chain: 4: PDB Molecule:skeletal muscle actin; PDBTitle: molecular models of averaged rigor crossbridges from2 tomograms of insect flight muscle 10 c2p9lA_ 100.0 18 PDB header:structural protein Chain: A: PDB Molecule:actin-like protein 3; PDBTitle: crystal structure of bovine arp2/3 complex 11 c3dwlB_ 100.0 18 PDB header:structural protein Chain: B: PDB Molecule:actin-related protein 3; PDBTitle: crystal structure of fission yeast arp2/3 complex lacking the arp22 subunit 12 c3h1qB_ 100.0 26 PDB header:structural protein Chain: B: PDB Molecule:ethanolamine utilization protein eutj; PDBTitle: crystal structure of ethanolamine utilization protein eutj from2 carboxydothermus hydrogenoformans 13 c3qb0C_ 100.0 19 PDB header:structural protein Chain: C: PDB Molecule:actin-related protein 4; PDBTitle: crystal structure of actin-related protein arp4 from s. cerevisiae2 complexed with atp 14 c1e4gT_ 100.0 19 PDB header:bacterial cell division Chain: T: PDB Molecule:cell division protein ftsa; PDBTitle: ftsa (atp-bound form) from thermotoga maritima 15 d1jcea2 100.0 53 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 16 c2d0oA_ 100.0 21 PDB header:chaperone Chain: A: PDB Molecule:diol dehydratase-reactivating factor large PDBTitle: strcuture of diol dehydratase-reactivating factor complexed2 with adp and mg2+ 17 c2fsnB_ 100.0 19 PDB header:structural protein Chain: B: PDB Molecule:hypothetical protein ta0583; PDBTitle: crystal structure of ta0583, an archaeal actin homolog, complex with2 adp 18 c1mwmA_ 100.0 12 PDB header:structural protein Chain: A: PDB Molecule:parm; PDBTitle: parm from plasmid r1 adp form 19 d1bupa2 100.0 18 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 20 d1dkgd2 100.0 18 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 21 d2e8aa2 not modelled 99.9 18 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 22 c2ychA_ not modelled 99.9 23 PDB header:cell cycle Chain: A: PDB Molecule:competence protein pilm; PDBTitle: pilm-piln type iv pilus biogenesis complex 23 c3js6A_ not modelled 99.9 19 PDB header:unknown function Chain: A: PDB Molecule:uncharacterized parm protein; PDBTitle: crystal structure of apo psk41 parm protein 24 c2p9kB_ not modelled 99.9 20 PDB header:structural protein Chain: B: PDB Molecule:actin-like protein 2; PDBTitle: crystal structure of bovine arp2/3 complex co-crystallized2 with atp and crosslinked with glutaraldehyde 25 d1e4ft2 not modelled 99.9 23 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 26 d1jcea1 not modelled 99.9 53 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 27 d2hf3a2 not modelled 99.9 17 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 28 d1nm1a2 not modelled 99.9 19 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 29 d2fxua2 not modelled 99.9 17 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 30 d1k8ka2 not modelled 99.8 18 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 31 d1yaga2 not modelled 99.8 17 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 32 d2zgya2 not modelled 99.8 14 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 33 d2e8aa1 not modelled 99.7 29 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 34 d1bupa1 not modelled 99.7 27 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 35 d1dkgd1 not modelled 99.7 29 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 36 d2fsja1 not modelled 99.7 21 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Ta0583-like 37 d1huxa_ not modelled 99.6 17 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like 38 d1k8kb1 not modelled 99.6 19 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 39 d1k8ka1 not modelled 99.4 18 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 40 d1yaga1 not modelled 99.3 15 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 41 d1c0fa1 not modelled 99.2 16 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 42 d2fxua1 not modelled 99.2 15 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 43 d2hf3a1 not modelled 99.2 17 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 44 d2ewsa1 not modelled 99.1 14 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Fumble-like 45 c2e2pA_ not modelled 98.9 10 PDB header:transferase Chain: A: PDB Molecule:hexokinase; PDBTitle: crystal structure of sulfolobus tokodaii hexokinase in2 complex with adp 46 c2aa4B_ not modelled 98.4 17 PDB header:transferase Chain: B: PDB Molecule:putative n-acetylmannosamine kinase; PDBTitle: crystal structure of escherichia coli putative n-2 acetylmannosamine kinase, new york structural genomics3 consortium 47 c1nbwA_ not modelled 98.4 20 PDB header:hydrolase Chain: A: PDB Molecule:glycerol dehydratase reactivase alpha subunit; PDBTitle: glycerol dehydratase reactivase 48 c3gg4B_ not modelled 98.3 10 PDB header:transferase Chain: B: PDB Molecule:glycerol kinase; PDBTitle: the crystal structure of glycerol kinase from yersinia2 pseudotuberculosis 49 c3ifrB_ not modelled 98.3 15 PDB header:transferase Chain: B: PDB Molecule:carbohydrate kinase, fggy; PDBTitle: the crystal structure of xylulose kinase from rhodospirillum rubrum 50 c3hz6A_ not modelled 98.3 19 PDB header:transferase Chain: A: PDB Molecule:xylulokinase; PDBTitle: crystal structure of xylulokinase from chromobacterium violaceum 51 d2d0oa3 not modelled 98.3 21 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ATPase domain of dehydratase reactivase alpha subunit 52 d2p3ra2 not modelled 98.2 16 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Glycerol kinase 53 c2ivoC_ not modelled 98.2 15 PDB header:hydrolase Chain: C: PDB Molecule:up1; PDBTitle: structure of up1 protein 54 c2nlxA_ not modelled 98.2 18 PDB header:transferase Chain: A: PDB Molecule:xylulose kinase; PDBTitle: crystal structure of the apo e. coli xylulose kinase 55 d1nbwa3 not modelled 98.2 22 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ATPase domain of dehydratase reactivase alpha subunit 56 c2zf5O_ not modelled 98.1 11 PDB header:transferase Chain: O: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of highly thermostable glycerol kinase from a2 hyperthermophilic archaeon 57 c2dpnB_ not modelled 98.1 20 PDB header:transferase Chain: B: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of the glycerol kinase from thermus2 thermophilus hb8 58 c1t6dB_ not modelled 98.1 16 PDB header:hydrolase Chain: B: PDB Molecule:exopolyphosphatase; PDBTitle: miras phasing of the aquifex aeolicus ppx/gppa phosphatase: crystal2 structure of the type ii variant 59 c3flcX_ not modelled 98.1 16 PDB header:transferase Chain: X: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of the his-tagged h232r mutant of glycerol kinase2 from enterococcus casseliflavus with glycerol 60 c1xupO_ not modelled 98.0 15 PDB header:transferase Chain: O: PDB Molecule:glycerol kinase; PDBTitle: enterococcus casseliflavus glycerol kinase complexed with glycerol 61 c2d4wA_ not modelled 98.0 16 PDB header:transferase Chain: A: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of glycerol kinase from cellulomonas sp.2 nt3060 62 c3g25B_ not modelled 98.0 12 PDB header:transferase Chain: B: PDB Molecule:glycerol kinase; PDBTitle: 1.9 angstrom crystal structure of glycerol kinase (glpk) from2 staphylococcus aureus in complex with glycerol. 63 d1r59o2 not modelled 98.0 16 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Glycerol kinase 64 c3hi0B_ not modelled 98.0 18 PDB header:hydrolase Chain: B: PDB Molecule:putative exopolyphosphatase; PDBTitle: crystal structure of putative exopolyphosphatase (17739545) from2 agrobacterium tumefaciens str. c58 (dupont) at 2.30 a resolution 65 c3gbtA_ not modelled 98.0 14 PDB header:transferase Chain: A: PDB Molecule:gluconate kinase; PDBTitle: crystal structure of gluconate kinase from lactobacillus acidophilus 66 c3jvpA_ not modelled 97.9 14 PDB header:transferase Chain: A: PDB Molecule:ribulokinase; PDBTitle: crystal structure of ribulokinase from bacillus halodurans 67 c2cgkB_ not modelled 97.9 18 PDB header:transferase Chain: B: PDB Molecule:l-rhamnulose kinase; PDBTitle: crystal structure of l-rhamnulose kinase from escherichia2 coli in an open uncomplexed conformation. 68 c1glbG_ not modelled 97.9 19 PDB header:phosphotransferase Chain: G: PDB Molecule:glycerol kinase; PDBTitle: structure of the regulatory complex of escherichia coli iiiglc with2 glycerol kinase 69 c2floA_ not modelled 97.9 16 PDB header:hydrolase Chain: A: PDB Molecule:exopolyphosphatase; PDBTitle: crystal structure of exopolyphosphatase (ppx) from e. coli o157:h7 70 c3i8bA_ not modelled 97.9 23 PDB header:transferase Chain: A: PDB Molecule:xylulose kinase; PDBTitle: the crystal structure of xylulose kinase from2 bifidobacterium adolescentis 71 c2ap1A_ not modelled 97.9 16 PDB header:transferase Chain: A: PDB Molecule:putative regulator protein; PDBTitle: crystal structure of the putative regulatory protein 72 c1z05A_ not modelled 97.9 16 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, rok family; PDBTitle: crystal structure of the rok family transcriptional regulator, homolog2 of e.coli mlc protein. 73 c2w40C_ not modelled 97.8 9 PDB header:transferase Chain: C: PDB Molecule:glycerol kinase, putative; PDBTitle: crystal structure of plasmodium falciparum glycerol kinase2 with bound glycerol 74 c3cetA_ not modelled 97.8 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved archaeal protein; PDBTitle: crystal structure of the pantheonate kinase-like protein2 q6m145 at the resolution 1.8 a. northeast structural3 genomics consortium target mrr63 75 c3htvA_ not modelled 97.8 13 PDB header:transferase Chain: A: PDB Molecule:d-allose kinase; PDBTitle: crystal structure of d-allose kinase (np_418508.1) from escherichia2 coli k12 at 1.95 a resolution 76 c3ezwD_ not modelled 97.8 17 PDB header:transferase Chain: D: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of a hyperactive escherichia coli glycerol kinase2 mutant gly230 --> asp obtained using microfluidic crystallization3 devices 77 c3cqyA_ not modelled 97.8 16 PDB header:transferase Chain: A: PDB Molecule:anhydro-n-acetylmuramic acid kinase; PDBTitle: crystal structure of a functionally unknown protein (so_1313) from2 shewanella oneidensis mr-1 78 c3vgkB_ not modelled 97.7 16 PDB header:transferase Chain: B: PDB Molecule:glucokinase; PDBTitle: crystal structure of a rok family glucokinase from streptomyces2 griseus 79 c3mdqA_ not modelled 97.7 20 PDB header:hydrolase Chain: A: PDB Molecule:exopolyphosphatase; PDBTitle: crystal structure of an exopolyphosphatase (chu_0316) from cytophaga2 hutchinsonii atcc 33406 at 1.50 a resolution 80 c1z6rC_ not modelled 97.6 12 PDB header:transcription Chain: C: PDB Molecule:mlc protein; PDBTitle: crystal structure of mlc from escherichia coli 81 c2qm1D_ not modelled 97.6 16 PDB header:transferase Chain: D: PDB Molecule:glucokinase; PDBTitle: crystal structure of glucokinase from enterococcus faecalis 82 c2ch5D_ not modelled 97.5 9 PDB header:transferase Chain: D: PDB Molecule:nagk protein; PDBTitle: crystal structure of human n-acetylglucosamine kinase in2 complex with n-acetylglucosamine 83 c3eo3B_ not modelled 97.5 15 PDB header:isomerase, transferase Chain: B: PDB Molecule:bifunctional udp-n-acetylglucosamine 2-epimerase/n- PDBTitle: crystal structure of the n-acetylmannosamine kinase domain of human2 gne protein 84 c2h3gX_ not modelled 97.5 21 PDB header:biosynthetic protein Chain: X: PDB Molecule:biosynthetic protein; PDBTitle: structure of the type iii pantothenate kinase (coax) from bacillus2 anthracis 85 c3enoB_ not modelled 97.3 16 PDB header:hydrolase/unknown function Chain: B: PDB Molecule:putative o-sialoglycoprotein endopeptidase; PDBTitle: crystal structure of pyrococcus furiosus pcc1 in complex2 with thermoplasma acidophilum kae1 86 c3cerD_ not modelled 97.2 18 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:possible exopolyphosphatase-like protein; PDBTitle: crystal structure of the exopolyphosphatase-like protein2 q8g5j2. northeast structural genomics consortium target3 blr13 87 c3r8eA_ not modelled 97.2 15 PDB header:transferase Chain: A: PDB Molecule:hypothetical sugar kinase; PDBTitle: crystal structure of a hypothetical sugar kinase (chu_1875) from2 cytophaga hutchinsonii atcc 33406 at 1.65 a resolution 88 d2i7pa1 not modelled 96.8 14 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Fumble-like 89 c2hoeA_ not modelled 96.4 14 PDB header:transferase Chain: A: PDB Molecule:n-acetylglucosamine kinase; PDBTitle: crystal structure of n-acetylglucosamine kinase (tm1224) from2 thermotoga maritima at 2.46 a resolution 90 d2i7na2 not modelled 96.4 13 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Fumble-like 91 c1zc6A_ not modelled 96.3 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:probable n-acetylglucosamine kinase; PDBTitle: crystal structure of putative n-acetylglucosamine kinase from2 chromobacterium violaceum. northeast structural genomics target3 cvr23. 92 d2zgya1 not modelled 96.3 8 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 93 d2aa4a2 not modelled 96.2 11 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ROK 94 c1sazA_ not modelled 96.2 16 PDB header:transferase Chain: A: PDB Molecule:probable butyrate kinase 2; PDBTitle: membership in the askha superfamily: enzymological2 properties and crystal structure of butyrate kinase 2 from3 thermotoga maritima 95 c2f9tB_ not modelled 96.1 16 PDB header:transferase Chain: B: PDB Molecule:pantothenate kinase; PDBTitle: structure of the type iii coaa from pseudomonas aeruginosa 96 c3qbwA_ not modelled 96.0 16 PDB header:transferase Chain: A: PDB Molecule:anhydro-n-acetylmuramic acid kinase; PDBTitle: crystal structure of pseudomonas aeruginosa 1,6-anhydro-n-2 actetylmuramic acid kinase (anmk) bound to adenosine diphosphate 97 d1u6za3 not modelled 95.9 29 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Ppx/GppA phosphatase 98 d1z05a2 not modelled 95.8 9 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ROK 99 c2i7pA_ not modelled 95.8 14 PDB header:transferase Chain: A: PDB Molecule:pantothenate kinase 3; PDBTitle: crystal structure of human pank3 in complex with accoa 100 d1t6ca2 not modelled 95.8 31 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Ppx/GppA phosphatase 101 c3tsuA_ not modelled 95.7 15 PDB header:transferase Chain: A: PDB Molecule:transcriptional regulatory protein; PDBTitle: crystal structure of e. coli hypf with amp-pnp and carbamoyl phosphate 102 c2gupA_ not modelled 95.7 13 PDB header:transferase Chain: A: PDB Molecule:rok family protein; PDBTitle: structural genomics, the crystal structure of a rok family protein2 from streptococcus pneumoniae tigr4 in complex with sucrose 103 d2ap1a1 not modelled 95.7 15 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ROK 104 d2fsja2 not modelled 95.1 17 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Ta0583-like 105 c3h6eB_ not modelled 94.9 14 PDB header:transferase Chain: B: PDB Molecule:carbohydrate kinase, fggy; PDBTitle: the crystal structure of a carbohydrate kinase from novosphingobium2 aromaticivorans 106 c3smpA_ not modelled 94.8 13 PDB header:transferase Chain: A: PDB Molecule:pantothenate kinase 1; PDBTitle: monoclinic crystal structure of human pantothenate kinase 1 alpha 107 c3en9B_ not modelled 94.6 13 PDB header:hydrolase Chain: B: PDB Molecule:o-sialoglycoprotein endopeptidase/protein kinase; PDBTitle: structure of the methanococcus jannaschii kae1-bud32 fusion2 protein 108 c3bf1C_ not modelled 94.6 16 PDB header:transferase Chain: C: PDB Molecule:type iii pantothenate kinase; PDBTitle: type iii pantothenate kinase from thermotoga maritima2 complexed with pantothenate and adp 109 d2hoea2 not modelled 94.3 13 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ROK 110 d2ch5a1 not modelled 94.1 11 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like 111 d1z6ra3 not modelled 93.7 8 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ROK 112 c3aapA_ not modelled 92.8 12 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleoside triphosphate diphosphohydrolase i; PDBTitle: crystal structure of lp1ntpdase from legionella pneumophila 113 d2gupa2 not modelled 91.6 10 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ROK 114 d1xc3a2 not modelled 91.1 11 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ROK 115 d2p3ra1 not modelled 90.9 22 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Glycerol kinase 116 c3djcA_ not modelled 90.6 18 PDB header:transferase Chain: A: PDB Molecule:type iii pantothenate kinase; PDBTitle: crystal structure of pantothenate kinase from legionella pneumophila 117 d1zc6a1 not modelled 90.0 18 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like 118 c3p4iA_ not modelled 89.8 15 PDB header:transferase Chain: A: PDB Molecule:acetate kinase; PDBTitle: crystal structure of acetate kinase from mycobacterium avium 119 d1saza2 not modelled 89.3 15 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Acetokinase-like 120 c1zxoB_ not modelled 88.6 15 PDB header:unknown function Chain: B: PDB Molecule:conserved hypothetical protein q8a1p1; PDBTitle: x-ray crystal structure of protein q8a1p1 from bacteroides2 thetaiotaomicron. northeast structural genomics consortium3 target btr25.