Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP25552
DateThu Jan 5 11:42:09 GMT 2012
Unique Job ID2fa7a3c7c5ef7b66

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2floA_
Top template information
PDB header:hydrolase
Chain: A: PDB Molecule:exopolyphosphatase;
PDBTitle: crystal structure of exopolyphosphatase (ppx) from e. coli o157:h7
Confidence and coverage
Confidence:100.0% Coverage: 99%
487 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENALSNEAMERG
Secondary structure 
SS confidence 
Disorder  ?????
?????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  WQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQEILGCPVQVISGEEEARLI
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  YQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRNLGQE
Secondary structure 
SS confidence 
Disorder 
??
??
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  NFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLK
Secondary structure 
SS confidence 
Disorder 
???????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  QRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGML
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  HLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVAANFFDQVENEWHLEAISRDLLISACQ
Secondary structure 
SS confidence 
Disorder 
?
???
?
??
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  LHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNPVDLSSLHQQNAVP
Secondary structure 
SS confidence 
Disorder 
??
????????????
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  PRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIAQE
Secondary structure 
SS confidence 
Disorder 
?
???????
Disorder confidence 
 
   .........490....
Sequence  SQWQSYVHWPLEVH
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2flo chain A

3D model

Region: 6 - 493
Aligned: 487
Modelled: 488
Confidence: 100.0%
Identity: 38%
PDB header:hydrolase
Chain: A: PDB Molecule:exopolyphosphatase;
PDBTitle: crystal structure of exopolyphosphatase (ppx) from e. coli o157:h7

Phyre2

PDB 3hi0 chain B

3D model

Region: 2 - 493
Aligned: 467
Modelled: 481
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: B: PDB Molecule:putative exopolyphosphatase;
PDBTitle: crystal structure of putative exopolyphosphatase (17739545) from2 agrobacterium tumefaciens str. c58 (dupont) at 2.30 a resolution

Phyre2

PDB 3mdq chain A

3D model

Region: 6 - 302
Aligned: 297
Modelled: 297
Confidence: 100.0%
Identity: 24%
PDB header:hydrolase
Chain: A: PDB Molecule:exopolyphosphatase;
PDBTitle: crystal structure of an exopolyphosphatase (chu_0316) from cytophaga2 hutchinsonii atcc 33406 at 1.50 a resolution

Phyre2

PDB 3cer chain D

3D model

Region: 8 - 302
Aligned: 295
Modelled: 295
Confidence: 100.0%
Identity: 28%
PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:possible exopolyphosphatase-like protein;
PDBTitle: crystal structure of the exopolyphosphatase-like protein2 q8g5j2. northeast structural genomics consortium target3 blr13

Phyre2

PDB 1t6d chain B

3D model

Region: 6 - 300
Aligned: 289
Modelled: 293
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: B: PDB Molecule:exopolyphosphatase;
PDBTitle: miras phasing of the aquifex aeolicus ppx/gppa phosphatase: crystal2 structure of the type ii variant

Phyre2

PDB 1u6z chain A domain 1

3D model

Region: 307 - 493
Aligned: 187
Modelled: 187
Confidence: 100.0%
Identity: 29%
Fold: HD-domain/PDEase-like
Superfamily: HD-domain/PDEase-like
Family: Ppx associated domain

Phyre2

PDB 1u6z chain A domain 3

3D model

Region: 131 - 306
Aligned: 176
Modelled: 176
Confidence: 100.0%
Identity: 40%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Ppx/GppA phosphatase

Phyre2

PDB 1t6c chain A domain 2

3D model

Region: 130 - 306
Aligned: 172
Modelled: 177
Confidence: 100.0%
Identity: 22%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Ppx/GppA phosphatase

Phyre2

PDB 1u6z chain A domain 2

3D model

Region: 8 - 130
Aligned: 123
Modelled: 123
Confidence: 100.0%
Identity: 53%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Ppx/GppA phosphatase

Phyre2

PDB 1t6c chain A domain 1

3D model

Region: 4 - 129
Aligned: 126
Modelled: 126
Confidence: 100.0%
Identity: 25%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Ppx/GppA phosphatase

Phyre2

PDB 3aap chain A

3D model

Region: 7 - 282
Aligned: 271
Modelled: 276
Confidence: 99.9%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:ectonucleoside triphosphate diphosphohydrolase i;
PDBTitle: crystal structure of lp1ntpdase from legionella pneumophila

Phyre2

PDB 3zx2 chain A

3D model

Region: 6 - 282
Aligned: 272
Modelled: 277
Confidence: 99.9%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:ectonucleoside triphosphate diphosphohydrolase 1;
PDBTitle: ntpdase1 in complex with decavanadate

Phyre2

PDB 3cj9 chain A

3D model

Region: 10 - 282
Aligned: 272
Modelled: 273
Confidence: 99.7%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:ectonucleoside triphosphate diphosphohydrolase 2;
PDBTitle: structure of rattus norvegicus ntpdase2 in complex with2 calcium, amp and phosphate

Phyre2

PDB 4a5b chain A

3D model

Region: 6 - 148
Aligned: 143
Modelled: 143
Confidence: 99.3%
Identity: 28%
PDB header:hydrolase
Chain: A: PDB Molecule:nucleoside-triphosphatase 2;
PDBTitle: crystal structure of the c258s/c268s variant of toxoplasma gondii2 nucleoside triphosphate diphosphohydrolase 1 (ntpdase1)

Phyre2

PDB 3agr chain B

3D model

Region: 6 - 148
Aligned: 143
Modelled: 143
Confidence: 99.3%
Identity: 27%
PDB header:hydrolase
Chain: B: PDB Molecule:nucleoside triphosphate hydrolase;
PDBTitle: crystal structure of nucleoside triphosphate hydrolases from neospora2 caninum

Phyre2

PDB 3h1q chain B

3D model

Region: 1 - 216
Aligned: 200
Modelled: 206
Confidence: 99.3%
Identity: 13%
PDB header:structural protein
Chain: B: PDB Molecule:ethanolamine utilization protein eutj;
PDBTitle: crystal structure of ethanolamine utilization protein eutj from2 carboxydothermus hydrogenoformans

Phyre2

PDB 1e4g chain T

3D model

Region: 5 - 216
Aligned: 202
Modelled: 212
Confidence: 99.0%
Identity: 20%
PDB header:bacterial cell division
Chain: T: PDB Molecule:cell division protein ftsa;
PDBTitle: ftsa (atp-bound form) from thermotoga maritima

Phyre2

PDB 2ych chain A

3D model

Region: 10 - 216
Aligned: 198
Modelled: 207
Confidence: 98.9%
Identity: 18%
PDB header:cell cycle
Chain: A: PDB Molecule:competence protein pilm;
PDBTitle: pilm-piln type iv pilus biogenesis complex

Phyre2

PDB 3js6 chain A

3D model

Region: 4 - 224
Aligned: 221
Modelled: 221
Confidence: 98.2%
Identity: 12%
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized parm protein;
PDBTitle: crystal structure of apo psk41 parm protein

Phyre2

PDB 1mwm chain A

3D model

Region: 7 - 224
Aligned: 218
Modelled: 218
Confidence: 98.1%
Identity: 17%
PDB header:structural protein
Chain: A: PDB Molecule:parm;
PDBTitle: parm from plasmid r1 adp form

Phyre2
1
c2floA_
2
c3hi0B_
3
c3mdqA_
4
c3cerD_
5
c1t6dB_
6
d1u6za1
7
d1u6za3
8
d1t6ca2
9
d1u6za2
10
d1t6ca1
11
c3aapA_
12
c3zx2A_
13
c3cj9A_
14
c4a5bA_
15
c3agrB_
16
c3h1qB_
17
c1e4gT_
18
c2ychA_
19
c3js6A_
20
c1mwmA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2floA_
100.0 38 PDB header:hydrolase
Chain: A: PDB Molecule:exopolyphosphatase;
PDBTitle: crystal structure of exopolyphosphatase (ppx) from e. coli o157:h7
2c3hi0B_
100.0 20 PDB header:hydrolase
Chain: B: PDB Molecule:putative exopolyphosphatase;
PDBTitle: crystal structure of putative exopolyphosphatase (17739545) from2 agrobacterium tumefaciens str. c58 (dupont) at 2.30 a resolution
3c3mdqA_
100.0 24 PDB header:hydrolase
Chain: A: PDB Molecule:exopolyphosphatase;
PDBTitle: crystal structure of an exopolyphosphatase (chu_0316) from cytophaga2 hutchinsonii atcc 33406 at 1.50 a resolution
4c3cerD_
100.0 28 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:possible exopolyphosphatase-like protein;
PDBTitle: crystal structure of the exopolyphosphatase-like protein2 q8g5j2. northeast structural genomics consortium target3 blr13
5c1t6dB_
100.0 23 PDB header:hydrolase
Chain: B: PDB Molecule:exopolyphosphatase;
PDBTitle: miras phasing of the aquifex aeolicus ppx/gppa phosphatase: crystal2 structure of the type ii variant
6d1u6za1
100.0 29 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:Ppx associated domain
7d1u6za3
100.0 40 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Ppx/GppA phosphatase
8d1t6ca2
100.0 22 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Ppx/GppA phosphatase
9d1u6za2
100.0 53 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Ppx/GppA phosphatase
10d1t6ca1
100.0 25 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Ppx/GppA phosphatase
11c3aapA_
99.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:ectonucleoside triphosphate diphosphohydrolase i;
PDBTitle: crystal structure of lp1ntpdase from legionella pneumophila
12c3zx2A_
99.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:ectonucleoside triphosphate diphosphohydrolase 1;
PDBTitle: ntpdase1 in complex with decavanadate
13c3cj9A_
99.7 14 PDB header:hydrolase
Chain: A: PDB Molecule:ectonucleoside triphosphate diphosphohydrolase 2;
PDBTitle: structure of rattus norvegicus ntpdase2 in complex with2 calcium, amp and phosphate
14c4a5bA_
99.3 28 PDB header:hydrolase
Chain: A: PDB Molecule:nucleoside-triphosphatase 2;
PDBTitle: crystal structure of the c258s/c268s variant of toxoplasma gondii2 nucleoside triphosphate diphosphohydrolase 1 (ntpdase1)
15c3agrB_
99.3 27 PDB header:hydrolase
Chain: B: PDB Molecule:nucleoside triphosphate hydrolase;
PDBTitle: crystal structure of nucleoside triphosphate hydrolases from neospora2 caninum
16c3h1qB_
99.3 13 PDB header:structural protein
Chain: B: PDB Molecule:ethanolamine utilization protein eutj;
PDBTitle: crystal structure of ethanolamine utilization protein eutj from2 carboxydothermus hydrogenoformans
17c1e4gT_
99.0 20 PDB header:bacterial cell division
Chain: T: PDB Molecule:cell division protein ftsa;
PDBTitle: ftsa (atp-bound form) from thermotoga maritima
18c2ychA_
98.9 18 PDB header:cell cycle
Chain: A: PDB Molecule:competence protein pilm;
PDBTitle: pilm-piln type iv pilus biogenesis complex
19c3js6A_
98.2 12 PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized parm protein;
PDBTitle: crystal structure of apo psk41 parm protein
20c1mwmA_
98.1 17 PDB header:structural protein
Chain: A: PDB Molecule:parm;
PDBTitle: parm from plasmid r1 adp form
21c2fsnB_
not modelled 98.0 15 PDB header:structural protein
Chain: B: PDB Molecule:hypothetical protein ta0583;
PDBTitle: crystal structure of ta0583, an archaeal actin homolog, complex with2 adp
22c3dwlB_
not modelled 98.0 16 PDB header:structural protein
Chain: B: PDB Molecule:actin-related protein 3;
PDBTitle: crystal structure of fission yeast arp2/3 complex lacking the arp22 subunit
23c3d2fC_
not modelled 98.0 17 PDB header:chaperone
Chain: C: PDB Molecule:heat shock protein homolog sse1;
PDBTitle: crystal structure of a complex of sse1p and hsp70
24c2p9lA_
not modelled 97.9 13 PDB header:structural protein
Chain: A: PDB Molecule:actin-like protein 3;
PDBTitle: crystal structure of bovine arp2/3 complex
25c2o08B_
not modelled 97.9 19 PDB header:hydrolase
Chain: B: PDB Molecule:bh1327 protein;
PDBTitle: crystal structure of a putative hd superfamily hydrolase (bh1327) from2 bacillus halodurans at 1.90 a resolution
26c3gw7A_
not modelled 97.8 13 PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized protein yedj;
PDBTitle: crystal structure of a metal-dependent phosphohydrolase2 with conserved hd domain (yedj) from escherichia coli in3 complex with nickel ions. northeast structural genomics4 consortium target er63
27c1jcgA_
not modelled 97.8 17 PDB header:structural protein
Chain: A: PDB Molecule:rod shape-determining protein mreb;
PDBTitle: mreb from thermotoga maritima, amppnp
28c2v7zA_
not modelled 97.8 19 PDB header:chaperone
Chain: A: PDB Molecule:heat shock cognate 71 kda protein;
PDBTitle: crystal structure of the 70-kda heat shock cognate protein2 from rattus norvegicus in post-atp hydrolysis state
29c1o1f4_
not modelled 97.8 12 PDB header:contractile protein
Chain: 4: PDB Molecule:skeletal muscle actin;
PDBTitle: molecular models of averaged rigor crossbridges from2 tomograms of insect flight muscle
30c2d0oA_
not modelled 97.7 18 PDB header:chaperone
Chain: A: PDB Molecule:diol dehydratase-reactivating factor large
PDBTitle: strcuture of diol dehydratase-reactivating factor complexed2 with adp and mg2+
31d2pq7a1
not modelled 97.7 21 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
32d2qgsa1
not modelled 97.7 16 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
33c3iucC_
not modelled 97.7 18 PDB header:chaperone
Chain: C: PDB Molecule:heat shock 70kda protein 5 (glucose-regulated
PDBTitle: crystal structure of the human 70kda heat shock protein 52 (bip/grp78) atpase domain in complex with adp
34c2ogiA_
not modelled 97.7 13 PDB header:hydrolase
Chain: A: PDB Molecule:hypothetical protein sag1661;
PDBTitle: crystal structure of a putative metal dependent phosphohydrolase2 (sag1661) from streptococcus agalactiae serogroup v at 1.85 a3 resolution
35c3qb0C_
not modelled 97.6 18 PDB header:structural protein
Chain: C: PDB Molecule:actin-related protein 4;
PDBTitle: crystal structure of actin-related protein arp4 from s. cerevisiae2 complexed with atp
36c1dkgD_
not modelled 97.5 19 PDB header:complex (hsp24/hsp70)
Chain: D: PDB Molecule:molecular chaperone dnak;
PDBTitle: crystal structure of the nucleotide exchange factor grpe2 bound to the atpase domain of the molecular chaperone dnak
37c3ccgA_
not modelled 97.5 14 PDB header:hydrolase
Chain: A: PDB Molecule:hd superfamily hydrolase;
PDBTitle: crystal structure of predicted hd superfamily hydrolase involved in2 nad metabolism (np_347894.1) from clostridium acetobutylicum at 1.503 a resolution
38d1e4ft2
not modelled 97.4 15 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
39d3b57a1
not modelled 97.3 10 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
40c1hpmA_
not modelled 97.3 18 PDB header:hydrolase (acting on acid anhydrides)
Chain: A: PDB Molecule:44k atpase fragment (n-terminal) of 7o kd heat-
PDBTitle: how potassium affects the activity of the molecular2 chaperone hsc70. ii. potassium binds specifically in the3 atpase active site
41c2khoA_
not modelled 97.2 21 PDB header:chaperone
Chain: A: PDB Molecule:heat shock protein 70;
PDBTitle: nmr-rdc / xray structure of e. coli hsp70 (dnak) chaperone2 (1-605) complexed with adp and substrate
42d1jcea2
not modelled 97.1 23 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
43c2v7yA_
not modelled 97.1 20 PDB header:chaperone
Chain: A: PDB Molecule:chaperone protein dnak;
PDBTitle: crystal structure of the molecular chaperone dnak from2 geobacillus kaustophilus hta426 in post-atp hydrolysis3 state
44d2pjqa1
not modelled 97.0 13 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
45d2zgya2
not modelled 96.9 18 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
46d2fsja1
not modelled 96.7 17 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Ta0583-like
47d3djba1
not modelled 96.7 20 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
48d1e4ft1
not modelled 96.5 20 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
49d2heka1
not modelled 96.5 11 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
50c3u1nC_
not modelled 96.2 11 PDB header:hydrolase
Chain: C: PDB Molecule:sam domain and hd domain-containing protein 1;
PDBTitle: structure of the catalytic core of human samhd1
51c3skdA_
not modelled 96.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:putative uncharacterized protein tthb187;
PDBTitle: crystal structure of the thermus thermophilus cas3 hd domain in the2 presence of ni2+
52d3dtoa1
not modelled 96.0 10 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
53c2zf5O_
not modelled 95.6 12 PDB header:transferase
Chain: O: PDB Molecule:glycerol kinase;
PDBTitle: crystal structure of highly thermostable glycerol kinase from a2 hyperthermophilic archaeon
54d2p3ra1
not modelled 95.5 15 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Glycerol kinase
55c2q14A_
not modelled 95.4 13 PDB header:hydrolase
Chain: A: PDB Molecule:phosphohydrolase;
PDBTitle: crystal structure of phosphohydrolase (bt4208) from bacteroides2 thetaiotaomicron vpi-5482 at 2.20 a resolution
56d2o6ia1
not modelled 95.3 18 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
57c2o6iA_
not modelled 95.3 18 PDB header:hydrolase
Chain: A: PDB Molecule:hd domain protein;
PDBTitle: structure of an enterococcus faecalis hd domain phosphohydrolase
58d1bupa2
not modelled 95.3 15 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
59d2ewsa1
not modelled 95.2 17 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Fumble-like
60c2nlxA_
not modelled 95.1 13 PDB header:transferase
Chain: A: PDB Molecule:xylulose kinase;
PDBTitle: crystal structure of the apo e. coli xylulose kinase
61c3gbtA_
not modelled 95.1 9 PDB header:transferase
Chain: A: PDB Molecule:gluconate kinase;
PDBTitle: crystal structure of gluconate kinase from lactobacillus acidophilus
62c2e2pA_
not modelled 95.0 8 PDB header:transferase
Chain: A: PDB Molecule:hexokinase;
PDBTitle: crystal structure of sulfolobus tokodaii hexokinase in2 complex with adp
63c3flcX_
not modelled 94.8 15 PDB header:transferase
Chain: X: PDB Molecule:glycerol kinase;
PDBTitle: crystal structure of the his-tagged h232r mutant of glycerol kinase2 from enterococcus casseliflavus with glycerol
64c3ezwD_
not modelled 94.7 15 PDB header:transferase
Chain: D: PDB Molecule:glycerol kinase;
PDBTitle: crystal structure of a hyperactive escherichia coli glycerol kinase2 mutant gly230 --> asp obtained using microfluidic crystallization3 devices
65c2d4wA_
not modelled 94.6 15 PDB header:transferase
Chain: A: PDB Molecule:glycerol kinase;
PDBTitle: crystal structure of glycerol kinase from cellulomonas sp.2 nt3060
66c1glbG_
not modelled 94.6 15 PDB header:phosphotransferase
Chain: G: PDB Molecule:glycerol kinase;
PDBTitle: structure of the regulatory complex of escherichia coli iiiglc with2 glycerol kinase
67d1huxa_
not modelled 94.6 17 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:BadF/BadG/BcrA/BcrD-like
68c3g25B_
not modelled 94.5 16 PDB header:transferase
Chain: B: PDB Molecule:glycerol kinase;
PDBTitle: 1.9 angstrom crystal structure of glycerol kinase (glpk) from2 staphylococcus aureus in complex with glycerol.
69c3memA_
not modelled 94.5 27 PDB header:signaling protein
Chain: A: PDB Molecule:putative signal transduction protein;
PDBTitle: crystal structure of a putative signal transduction protein2 (maqu_0641) from marinobacter aquaeolei vt8 at 2.25 a resolution
70c2w40C_
not modelled 94.4 9 PDB header:transferase
Chain: C: PDB Molecule:glycerol kinase, putative;
PDBTitle: crystal structure of plasmodium falciparum glycerol kinase2 with bound glycerol
71c3ifrB_
not modelled 94.2 9 PDB header:transferase
Chain: B: PDB Molecule:carbohydrate kinase, fggy;
PDBTitle: the crystal structure of xylulose kinase from rhodospirillum rubrum
72c2dqbB_
not modelled 94.0 16 PDB header:hydrolase, dna binding protein
Chain: B: PDB Molecule:deoxyguanosinetriphosphate triphosphohydrolase, putative;
PDBTitle: crystal structure of dntp triphosphohydrolase from thermus2 thermophilus hb8, which is homologous to dgtp triphosphohydrolase
73d1dkgd2
not modelled 94.0 14 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
74d2e8aa2
not modelled 93.9 17 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
75c3jvpA_
not modelled 93.8 6 PDB header:transferase
Chain: A: PDB Molecule:ribulokinase;
PDBTitle: crystal structure of ribulokinase from bacillus halodurans
76c2dpnB_
not modelled 93.8 14 PDB header:transferase
Chain: B: PDB Molecule:glycerol kinase;
PDBTitle: crystal structure of the glycerol kinase from thermus2 thermophilus hb8
77c2hoeA_
not modelled 93.7 11 PDB header:transferase
Chain: A: PDB Molecule:n-acetylglucosamine kinase;
PDBTitle: crystal structure of n-acetylglucosamine kinase (tm1224) from2 thermotoga maritima at 2.46 a resolution
78c3m1tA_
not modelled 93.4 20 PDB header:hydrolase
Chain: A: PDB Molecule:putative phosphohydrolase;
PDBTitle: crystal structure of putative phosphohydrolase (yp_929327.1) from2 shewanella amazonensis sb2b at 1.62 a resolution
79c3hz6A_
not modelled 93.2 7 PDB header:transferase
Chain: A: PDB Molecule:xylulokinase;
PDBTitle: crystal structure of xylulokinase from chromobacterium violaceum
80c1nbwA_
not modelled 93.1 24 PDB header:hydrolase
Chain: A: PDB Molecule:glycerol dehydratase reactivase alpha subunit;
PDBTitle: glycerol dehydratase reactivase
81c3gg4B_
not modelled 92.9 16 PDB header:transferase
Chain: B: PDB Molecule:glycerol kinase;
PDBTitle: the crystal structure of glycerol kinase from yersinia2 pseudotuberculosis
82c3m5fA_
not modelled 92.3 16 PDB header:hydrolase
Chain: A: PDB Molecule:metal dependent phosphohydrolase;
PDBTitle: structure of mj0384, a cas3 protein from methanocaldococcus jannaschii
83c1z6rC_
not modelled 92.0 14 PDB header:transcription
Chain: C: PDB Molecule:mlc protein;
PDBTitle: crystal structure of mlc from escherichia coli
84c3bg2A_
not modelled 91.9 20 PDB header:hydrolase
Chain: A: PDB Molecule:dgtp triphosphohydrolase;
PDBTitle: crystal structure of deoxyguanosinetriphosphate triphosphohydrolase2 from flavobacterium sp. med217
85d1nm1a2
not modelled 91.8 13 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
86c2pgsA_
not modelled 91.5 21 PDB header:hydrolase
Chain: A: PDB Molecule:putative deoxyguanosinetriphosphate triphosphohydrolase;
PDBTitle: crystal structure of a putative deoxyguanosinetriphosphate2 triphosphohydrolase from pseudomonas syringae pv. phaseolicola 1448a
87c3hc1A_
not modelled 90.7 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized hdod domain protein;
PDBTitle: crystal structure of hdod domain protein with unknown function2 (np_953345.1) from geobacter sulfurreducens at 1.90 a resolution
88d2hf3a2
not modelled 90.7 13 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
89d1k8kb1
not modelled 90.5 15 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
90c2qm1D_
not modelled 90.4 13 PDB header:transferase
Chain: D: PDB Molecule:glucokinase;
PDBTitle: crystal structure of glucokinase from enterococcus faecalis
91d2fxua2
not modelled 90.0 15 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
92c3h6eB_
not modelled 89.9 17 PDB header:transferase
Chain: B: PDB Molecule:carbohydrate kinase, fggy;
PDBTitle: the crystal structure of a carbohydrate kinase from novosphingobium2 aromaticivorans
93c3i8bA_
not modelled 89.8 14 PDB header:transferase
Chain: A: PDB Molecule:xylulose kinase;
PDBTitle: the crystal structure of xylulose kinase from2 bifidobacterium adolescentis
94c2cgkB_
not modelled 89.4 20 PDB header:transferase
Chain: B: PDB Molecule:l-rhamnulose kinase;
PDBTitle: crystal structure of l-rhamnulose kinase from escherichia2 coli in an open uncomplexed conformation.
95d1yaga2
not modelled 88.7 13 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
96c3bfjK_
not modelled 88.5 18 PDB header:oxidoreductase
Chain: K: PDB Molecule:1,3-propanediol oxidoreductase;
PDBTitle: crystal structure analysis of 1,3-propanediol oxidoreductase
97d1vqra_
not modelled 87.8 17 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:modified HD domain
98c1xupO_
not modelled 87.6 14 PDB header:transferase
Chain: O: PDB Molecule:glycerol kinase;
PDBTitle: enterococcus casseliflavus glycerol kinase complexed with glycerol
99d1zc6a1
not modelled 87.1 9 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:BadF/BadG/BcrA/BcrD-like
100d1y2ka1
not modelled 87.0 15 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:PDEase
101c3eo3B_
not modelled 86.8 16 PDB header:isomerase, transferase
Chain: B: PDB Molecule:bifunctional udp-n-acetylglucosamine 2-epimerase/n-
PDBTitle: crystal structure of the n-acetylmannosamine kinase domain of human2 gne protein
102c3htvA_
not modelled 86.1 13 PDB header:transferase
Chain: A: PDB Molecule:d-allose kinase;
PDBTitle: crystal structure of d-allose kinase (np_418508.1) from escherichia2 coli k12 at 1.95 a resolution
103c2p9kB_
not modelled 85.7 15 PDB header:structural protein
Chain: B: PDB Molecule:actin-like protein 2;
PDBTitle: crystal structure of bovine arp2/3 complex co-crystallized2 with atp and crosslinked with glutaraldehyde
104c1ta9A_
not modelled 85.4 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol dehydrogenase;
PDBTitle: crystal structure of glycerol dehydrogenase from schizosaccharomyces2 pombe
105c2r8qA_
not modelled 85.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:class i phosphodiesterase pdeb1;
PDBTitle: structure of lmjpdeb1 in complex with ibmx
106c1z1lA_
not modelled 85.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:cgmp-dependent 3',5'-cyclic phosphodiesterase;
PDBTitle: the crystal structure of the phosphodiesterase 2a catalytic2 domain
107d1k8ka2
not modelled 85.0 10 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Actin/HSP70
108c1xozA_
not modelled 84.8 12 PDB header:hydrolase
Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase;
PDBTitle: catalytic domain of human phosphodiesterase 5a in complex2 with tadalafil
109d1tbfa_
not modelled 84.8 12 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:PDEase
110c1xotB_
not modelled 84.5 13 PDB header:hydrolase
Chain: B: PDB Molecule:camp-specific 3',5'-cyclic phosphodiesterase 4b;
PDBTitle: catalytic domain of human phosphodiesterase 4b in complex with2 vardenafil
111c1xc3A_
not modelled 84.3 16 PDB header:transferase
Chain: A: PDB Molecule:putative fructokinase;
PDBTitle: structure of a putative fructokinase from bacillus subtilis
112c3cetA_
not modelled 83.7 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved archaeal protein;
PDBTitle: crystal structure of the pantheonate kinase-like protein2 q6m145 at the resolution 1.8 a. northeast structural3 genomics consortium target mrr63
113d1r59o1
not modelled 83.5 15 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:Glycerol kinase
114c3ox4D_
not modelled 83.0 14 PDB header:oxidoreductase
Chain: D: PDB Molecule:alcohol dehydrogenase 2;
PDBTitle: structures of iron-dependent alcohol dehydrogenase 2 from zymomonas2 mobilis zm4 complexed with nad cofactor
115c3ce9A_
not modelled 82.8 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol dehydrogenase;
PDBTitle: crystal structure of glycerol dehydrogenase (np_348253.1) from2 clostridium acetobutylicum at 2.37 a resolution
116c3g3nA_
not modelled 80.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:high affinity camp-specific 3',5'-cyclic
PDBTitle: pde7a catalytic domain in complex with 3-(2,6-2 difluorophenyl)-2-(methylthio)quinazolin-4(3h)-one
117d2gupa1
not modelled 80.9 20 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:ROK
118c3bjcA_
not modelled 79.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase;
PDBTitle: crystal structure of the pde5a catalytic domain in complex2 with a novel inhibitor
119d1z05a3
not modelled 79.4 14 Fold:Ribonuclease H-like motif
Superfamily:Actin-like ATPase domain
Family:ROK
120c3ibjB_
not modelled 78.2 17 PDB header:hydrolase
Chain: B: PDB Molecule:cgmp-dependent 3',5'-cyclic phosphodiesterase;
PDBTitle: x-ray structure of pde2a

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0