Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	E	A	M	K	I	T	L	S	T	Q	P	A	D	A	R	W	G	E	K	A	T	Y	S	I	N	N	D	G	I	T	L	H	L	N	G	A	D	D	L	G	L	I	Q	R	A	A	R	K	I	D	G	L	G	I	K	H	V	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?				?	?	?	?	?	?	?	?							?													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	S	G	E	G	W	D	A	D	R	C	W	A	F	W	Q	G	Y	K	A	P	K	G	T	R	K	V	V	W	P	D	L	D	D	A	Q	R	Q	E	L	D	N	R	L	M	I	I	D	W	V	R	D	T	I	N	A	P	A	E	E
Secondary structure
SS confidence
Disorder																		?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	G	P	S	Q	L	A	Q	R	A	V	D	L	I	S	N	V	A	G	D	R	V	T	Y	R	I	T	K	G	E	D	L	R	E	Q	G	Y	M	G	L	H	T	V	G	R	G	S	E	R	S	P	V	L	L	A	L	D	Y	N	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	G	D	K	E	A	P	V	Y	A	C	L	V	G	K	G	I	T	F	D	S	G	G	Y	S	I	K	Q	T	A	F	M	D	S	M	K	S	D	M	G	G	A	A	T	V	T	G	A	L	A	F	A	I	T	R	G	L	N	K	R
Secondary structure
SS confidence
Disorder				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	K	L	F	L	C	C	A	D	N	L	I	S	G	N	A	F	K	L	G	D	I	I	T	Y	R	N	G	K	K	V	E	V	M	N	T	D	A	E	G	R	L	V	L	A	D	G	L	I	D	A	S	A	Q	K	P	E	M	I	I
Secondary structure
SS confidence
Disorder																?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		D	A	A	T	L	T	G	A	A	K	T	A	L	G	N	D	Y	H	A	L	F	S	F	D	D	A	L	A	G	R	L	L	A	S	A	A	Q	E	N	E	P	F	W	R	L	P	L	A	E	F	H	R	S	Q	L	P	S	N	F	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		E	L	N	N	T	G	S	A	A	Y	P	A	G	A	S	T	A	A	G	F	L	S	H	F	V	E	N	Y	Q	Q	G	W	L	H	I	D	C	S	A	T	Y	R	K	A	P	V	E	Q	W	S	A	G	A	T	G	L	G	V	R	T
Secondary structure
SS confidence
Disorder								?	?	?	?	?																																		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.
Sequence		I	A	N	L	L	T	A
Secondary structure
SS confidence
Disorder							?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3kzw chain D Region: 36 - 425 Aligned: 371 Modelled: 387 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: D: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from staphylococcus aureus2 col Phyre2 PDB 3h8g chain C Region: 66 - 426 Aligned: 351 Modelled: 361 Confidence: 100.0% Identity: 36% PDB header:hydrolase Chain: C: PDB Molecule:cytosol aminopeptidase; PDBTitle: bestatin complex structure of leucine aminopeptidase from pseudomonas2 putida Phyre2 PDB 3jru chain B Region: 39 - 426 Aligned: 365 Modelled: 388 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: B: PDB Molecule:probable cytosol aminopeptidase; PDBTitle: crystal structure of leucyl aminopeptidase (pepa) from xoo0834,2 xanthomonas oryzae pv. oryzae kacc10331 Phyre2 PDB 1lan chain A Region: 44 - 426 Aligned: 378 Modelled: 383 Confidence: 100.0% Identity: 33% PDB header:hydrolase (alpha-aminoacylpeptide) Chain: A: PDB Molecule:leucine aminopeptidase; PDBTitle: leucine aminopeptidase complex with l-leucinal Phyre2 PDB 1gyt chain G Region: 35 - 426 Aligned: 383 Modelled: 392 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: G: PDB Molecule:cytosol aminopeptidase; PDBTitle: e. coli aminopeptidase a (pepa) Phyre2 PDB 3ij3 chain A Region: 70 - 425 Aligned: 345 Modelled: 355 Confidence: 100.0% Identity: 37% PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: 1.8 angstrom resolution crystal structure of cytosol aminopeptidase2 from coxiella burnetii Phyre2 PDB 3kr5 chain E Region: 35 - 426 Aligned: 380 Modelled: 392 Confidence: 100.0% Identity: 31% PDB header:hydrolase Chain: E: PDB Molecule:m17 leucyl aminopeptidase; PDBTitle: structure of a protease 4 Phyre2 PDB 1gyt chain A domain 2 Region: 102 - 426 Aligned: 316 Modelled: 325 Confidence: 100.0% Identity: 38% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Leucine aminopeptidase, C-terminal domain Phyre2 PDB 1lam chain A domain 1 Region: 103 - 426 Aligned: 319 Modelled: 324 Confidence: 100.0% Identity: 36% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Leucine aminopeptidase, C-terminal domain Phyre2 PDB 2hc9 chain A Region: 27 - 425 Aligned: 374 Modelled: 396 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:leucine aminopeptidase 1; PDBTitle: structure of caenorhabditis elegans leucine aminopeptidase-zinc2 complex (lap1) Phyre2 PDB 3pei chain A Region: 21 - 426 Aligned: 365 Modelled: 377 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from francisella2 tularensis Phyre2 PDB 1vhe chain A domain 2 Region: 105 - 249 Aligned: 119 Modelled: 130 Confidence: 96.0% Identity: 12% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Bacterial dinuclear zinc exopeptidases Phyre2 PDB 2gre chain A domain 2 Region: 102 - 262 Aligned: 112 Modelled: 126 Confidence: 92.0% Identity: 13% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Bacterial dinuclear zinc exopeptidases Phyre2 PDB 1ylo chain A domain 2 Region: 107 - 249 Aligned: 115 Modelled: 131 Confidence: 91.5% Identity: 13% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Bacterial dinuclear zinc exopeptidases Phyre2 PDB 3rza chain A Region: 105 - 253 Aligned: 138 Modelled: 149 Confidence: 90.2% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:tripeptidase; PDBTitle: crystal structure of a tripeptidase (sav1512) from staphylococcus2 aureus subsp. aureus mu50 at 2.10 a resolution Phyre2 PDB 1vho chain A domain 2 Region: 105 - 249 Aligned: 116 Modelled: 127 Confidence: 83.9% Identity: 9% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Bacterial dinuclear zinc exopeptidases Phyre2 PDB 3ct9 chain B Region: 101 - 258 Aligned: 133 Modelled: 156 Confidence: 83.6% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:acetylornithine deacetylase; PDBTitle: crystal structure of a putative zinc peptidase (np_812461.1) from2 bacteroides thetaiotaomicron vpi-5482 at 2.31 a resolution Phyre2 PDB 2fvg chain A domain 2 Region: 109 - 244 Aligned: 108 Modelled: 122 Confidence: 81.9% Identity: 15% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Bacterial dinuclear zinc exopeptidases Phyre2 PDB 3gb0 chain A Region: 102 - 249 Aligned: 136 Modelled: 142 Confidence: 78.6% Identity: 9% PDB header:hydrolase Chain: A: PDB Molecule:peptidase t; PDBTitle: crystal structure of aminopeptidase pept (np_980509.1) from bacillus2 cereus atcc 10987 at 2.04 a resolution Phyre2 PDB 3t6m chain A Region: 105 - 249 Aligned: 124 Modelled: 132 Confidence: 78.4% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of the catalytic domain of dape protein from2 v.cholerea in the zn bound form Phyre2 1 c3kzwD_ 2 c3h8gC_ 3 c3jruB_ 4 c1lanA_ 5 c1gytG_ 6 c3ij3A_ 7 c3kr5E_ 8 d1gyta2 9 d1lama1 10 c2hc9A_ 11 c3peiA_ 12 d1vhea2 13 d2grea2 14 d1yloa2 15 c3rzaA_ 16 d1vhoa2 17 c3ct9B_ 18 d2fvga2 19 c3gb0A_ 20 c3t6mA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3kzwD_ 100.0 33 PDB header:hydrolase Chain: D: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from staphylococcus aureus2 col 2 c3h8gC_ 100.0 36 PDB header:hydrolase Chain: C: PDB Molecule:cytosol aminopeptidase; PDBTitle: bestatin complex structure of leucine aminopeptidase from pseudomonas2 putida 3 c3jruB_ 100.0 33 PDB header:hydrolase Chain: B: PDB Molecule:probable cytosol aminopeptidase; PDBTitle: crystal structure of leucyl aminopeptidase (pepa) from xoo0834,2 xanthomonas oryzae pv. oryzae kacc10331 4 c1lanA_ 100.0 33 PDB header:hydrolase (alpha-aminoacylpeptide) Chain: A: PDB Molecule:leucine aminopeptidase; PDBTitle: leucine aminopeptidase complex with l-leucinal 5 c1gytG_ 100.0 34 PDB header:hydrolase Chain: G: PDB Molecule:cytosol aminopeptidase; PDBTitle: e. coli aminopeptidase a (pepa) 6 c3ij3A_ 100.0 37 PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: 1.8 angstrom resolution crystal structure of cytosol aminopeptidase2 from coxiella burnetii 7 c3kr5E_ 100.0 31 PDB header:hydrolase Chain: E: PDB Molecule:m17 leucyl aminopeptidase; PDBTitle: structure of a protease 4 8 d1gyta2 100.0 38 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Leucine aminopeptidase, C-terminal domain 9 d1lama1 100.0 36 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Leucine aminopeptidase, C-terminal domain 10 c2hc9A_ 100.0 27 PDB header:hydrolase Chain: A: PDB Molecule:leucine aminopeptidase 1; PDBTitle: structure of caenorhabditis elegans leucine aminopeptidase-zinc2 complex (lap1) 11 c3peiA_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from francisella2 tularensis 12 d1vhea2 96.0 12 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 13 d2grea2 92.0 13 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 14 d1yloa2 91.5 13 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 15 c3rzaA_ 90.2 10 PDB header:hydrolase Chain: A: PDB Molecule:tripeptidase; PDBTitle: crystal structure of a tripeptidase (sav1512) from staphylococcus2 aureus subsp. aureus mu50 at 2.10 a resolution 16 d1vhoa2 83.9 9 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 17 c3ct9B_ 83.6 11 PDB header:hydrolase Chain: B: PDB Molecule:acetylornithine deacetylase; PDBTitle: crystal structure of a putative zinc peptidase (np_812461.1) from2 bacteroides thetaiotaomicron vpi-5482 at 2.31 a resolution 18 d2fvga2 81.9 15 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 19 c3gb0A_ 78.6 9 PDB header:hydrolase Chain: A: PDB Molecule:peptidase t; PDBTitle: crystal structure of aminopeptidase pept (np_980509.1) from bacillus2 cereus atcc 10987 at 2.04 a resolution 20 c3t6mA_ 78.4 13 PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of the catalytic domain of dape protein from2 v.cholerea in the zn bound form 21 d1vgya1 not modelled 76.4 9 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 22 d2hgaa1 not modelled 73.8 13 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:MTH1368 C-terminal domain-like 23 d1xmba1 not modelled 71.0 19 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 24 d1cg2a1 not modelled 64.3 14 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 25 c3pfoB_ not modelled 63.1 9 PDB header:hydrolase Chain: B: PDB Molecule:putative acetylornithine deacetylase; PDBTitle: crystal structure of a putative acetylornithine deacetylase (rpa2325)2 from rhodopseudomonas palustris cga009 at 1.90 a resolution 26 c1ysjB_ not modelled 61.9 13 PDB header:hydrolase Chain: B: PDB Molecule:protein yxep; PDBTitle: crystal structure of bacillus subtilis yxep protein (apc1829), a2 dinuclear metal binding peptidase from m20 family 27 c2q43A_ not modelled 60.5 14 PDB header:hydrolase Chain: A: PDB Molecule:iaa-amino acid hydrolase ilr1-like 2; PDBTitle: ensemble refinement of the protein crystal structure of iaa-aminoacid2 hydrolase from arabidopsis thaliana gene at5g56660 28 d1sota1 not modelled 58.4 19 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 29 c3i18A_ not modelled 56.1 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lmo2051 protein; PDBTitle: crystal structure of the pdz domain of the sdrc-like protein2 (lmo2051) from listeria monocytogenes, northeast structural3 genomics consortium target lmr166b 30 c1vhoA_ not modelled 54.6 8 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of a putative peptidase/endoglucanase 31 d1z2la1 not modelled 53.6 20 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 32 c2p3wB_ not modelled 52.4 30 PDB header:protein binding Chain: B: PDB Molecule:probable serine protease htra3; PDBTitle: crystal structure of the htra3 pdz domain bound to a phage-derived2 ligand (fgrwv) 33 c2qyvB_ not modelled 51.2 13 PDB header:hydrolase Chain: B: PDB Molecule:xaa-his dipeptidase; PDBTitle: crystal structure of putative xaa-his dipeptidase (yp_718209.1) from2 haemophilus somnus 129pt at 2.11 a resolution 34 c3pfeA_ not modelled 48.8 17 PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of a m20a metallo peptidase (dape, lpg0809) from2 legionella pneumophila subsp. pneumophila str. philadelphia 1 at 1.503 a resolution 35 d2z9ia1 not modelled 48.1 13 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 36 d1ky9a1 not modelled 47.4 33 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 37 c2kl1A_ not modelled 46.6 17 PDB header:protein binding Chain: A: PDB Molecule:ylbl protein; PDBTitle: solution structure of gtr34c from geobacillus thermodenitrificans.2 northeast structural genomics consortium target gtr34c 38 c2greC_ not modelled 45.2 16 PDB header:hydrolase Chain: C: PDB Molecule:deblocking aminopeptidase; PDBTitle: crystal structure of deblocking aminopeptidase from bacillus cereus 39 d1mfga_ not modelled 43.9 16 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 40 d1ky9b2 not modelled 43.9 21 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 41 c3io1B_ not modelled 42.9 13 PDB header:hydrolase Chain: B: PDB Molecule:aminobenzoyl-glutamate utilization protein; PDBTitle: crystal structure of aminobenzoyl-glutamate utilization2 protein from klebsiella pneumoniae 42 c2joaA_ not modelled 42.4 20 PDB header:protein binding Chain: A: PDB Molecule:serine protease htra1; PDBTitle: htra1 bound to an optimized peptide: nmr assignment of pdz2 domain and ligand resonances 43 d1xfoa2 not modelled 41.7 12 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 44 d1lcya1 not modelled 41.6 19 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 45 c2zplA_ not modelled 41.5 21 PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain a 46 d1ysja1 not modelled 41.4 16 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 47 c2kjpA_ not modelled 40.3 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein ylbl; PDBTitle: solution structure of protein ylbl (bsu15050) from bacillus2 subtilis, northeast structural genomics consortium target3 sr713a 48 d2h3la1 not modelled 39.4 16 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 49 c3pv4A_ not modelled 38.3 37 PDB header:hydrolase Chain: A: PDB Molecule:degq; PDBTitle: structure of legionella fallonii degq (delta-pdz2 variant) 50 c1vgyB_ not modelled 35.7 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of succinyl diaminopimelate desuccinylase 51 c3tc8A_ not modelled 34.2 13 PDB header:hydrolase Chain: A: PDB Molecule:leucine aminopeptidase; PDBTitle: crystal structure of a hypothetical zn-dependent exopeptidase2 (bdi_3547) from parabacteroides distasonis atcc 8503 at 1.06 a3 resolution 52 c1ky9A_ not modelled 34.2 32 PDB header:hydrolase Chain: A: PDB Molecule:protease do; PDBTitle: crystal structure of degp (htra) 53 c2r3yC_ not modelled 34.0 22 PDB header:hydrolase/hydrolase activator Chain: C: PDB Molecule:protease degs; PDBTitle: crystal structure of the degs protease in complex with the2 ywf activating peptide 54 c1lcyA_ not modelled 33.0 20 PDB header:hydrolase Chain: A: PDB Molecule:htra2 serine protease; PDBTitle: crystal structure of the mitochondrial serine protease htra2 55 d2i4sa1 not modelled 32.9 27 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:EpsC C-terminal domain-like 56 d2i6va1 not modelled 32.8 27 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:EpsC C-terminal domain-like 57 d1fc6a3 not modelled 31.8 27 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:Tail specific protease PDZ domain 58 c3bpuA_ not modelled 31.8 32 PDB header:transferase Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz domain- PDBTitle: crystal structure of the 3rd pdz domain of human membrane associated2 guanylate kinase, c677s and c709s double mutant 59 c3mruB_ not modelled 31.5 13 PDB header:hydrolase Chain: B: PDB Molecule:aminoacyl-histidine dipeptidase; PDBTitle: crystal structure of aminoacylhistidine dipeptidase from vibrio2 alginolyticus 60 c1vheA_ not modelled 29.6 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:aminopeptidase/glucanase homolog; PDBTitle: crystal structure of a aminopeptidase/glucanase homolog 61 c2hc8A_ not modelled 29.4 21 PDB header:transport protein Chain: A: PDB Molecule:cation-transporting atpase, p-type; PDBTitle: structure of the a. fulgidus copa a-domain 62 c1q7lA_ not modelled 28.0 6 PDB header:hydrolase Chain: A: PDB Molecule:aminoacylase-1; PDBTitle: zn-binding domain of the t347g mutant of human aminoacylase-2 i 63 d1ed7a_ not modelled 28.0 30 Fold:WW domain-like Superfamily:Carbohydrate binding domain Family:Carbohydrate binding domain 64 c2lbfA_ not modelled 26.9 28 PDB header:ribosomal protein Chain: A: PDB Molecule:60s acidic ribosomal protein p1; PDBTitle: solution structure of the dimerization domain of human ribosomal2 protein p1/p2 heterodimer 65 c3l4fD_ not modelled 26.2 20 PDB header:signaling protein/protein binding Chain: D: PDB Molecule:sh3 and multiple ankyrin repeat domains protein PDBTitle: crystal structure of betapix coiled-coil domain and shank2 pdz complex 66 c2cauA_ not modelled 25.0 23 PDB header:plant protein Chain: A: PDB Molecule:protein (canavalin); PDBTitle: canavalin from jack bean 67 c2zxeA_ not modelled 24.5 19 PDB header:hydrolase/transport protein Chain: A: PDB Molecule:na, k-atpase alpha subunit; PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state 68 c3pv5B_ not modelled 24.2 33 PDB header:hydrolase Chain: B: PDB Molecule:degq; PDBTitle: structure of legionella fallonii degq (n189g/p190g variant) 69 c3ixzA_ not modelled 23.2 22 PDB header:hydrolase Chain: A: PDB Molecule:potassium-transporting atpase alpha; PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride 70 d1sroa_ not modelled 22.8 32 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 71 c2zpmA_ not modelled 22.6 20 PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain b 72 c2fvgA_ not modelled 22.6 15 PDB header:hydrolase Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of endoglucanase (tm1049) from thermotoga maritima2 at 2.01 a resolution 73 c3stjC_ not modelled 22.5 37 PDB header:hydrolase Chain: C: PDB Molecule:protease degq; PDBTitle: crystal structure of the protease + pdz1 domain of degq from2 escherichia coli 74 c1cg2D_ not modelled 22.2 14 PDB header:metallocarboxypeptidase Chain: D: PDB Molecule:carboxypeptidase g2; PDBTitle: carboxypeptidase g2 75 c3gdsA_ not modelled 21.6 20 PDB header:hydrolase/hydrolase activator Chain: A: PDB Molecule:protease degs; PDBTitle: crystal structure of degs h198p/d320a mutant modified by dfp in2 complex with dnrdgnvyyf peptide 76 d1l1ca_ not modelled 21.1 29 Fold:GroES-like Superfamily:SacY-like RNA-binding domain Family:BglG-like antiterminator proteins 77 c3isxA_ not modelled 21.0 15 PDB header:hydrolase Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of endoglucanase (tm1050) from thermotoga2 maritima at 1.40 a resolution 78 c3shuB_ not modelled 20.9 13 PDB header:cell adhesion Chain: B: PDB Molecule:tight junction protein zo-1; PDBTitle: crystal structure of zo-1 pdz3 79 c2d90A_ not modelled 20.0 26 PDB header:protein binding Chain: A: PDB Molecule:pdz domain containing protein 1; PDBTitle: solution structure of the third pdz domain of pdz domain2 containing protein 1 80 c3khzA_ not modelled 19.8 13 PDB header:hydrolase Chain: A: PDB Molecule:putative dipeptidase sacol1801; PDBTitle: crystal structure of r350a mutant of staphylococcus aureus2 metallopeptidase (sapep/dape) in the apo-form 81 c2pokB_ not modelled 19.1 14 PDB header:hydrolase Chain: B: PDB Molecule:peptidase, m20/m25/m40 family; PDBTitle: crystal structure of a m20 family metallo peptidase from streptococcus2 pneumoniae 82 c2eguA_ not modelled 18.9 18 PDB header:transferase Chain: A: PDB Molecule:cysteine synthase; PDBTitle: crystal structure of o-acetylserine sulfhydrase from geobacillus2 kaustophilus hta426 83 c2z9iB_ not modelled 18.7 13 PDB header:hydrolase Chain: B: PDB Molecule:probable serine protease pepd; PDBTitle: crystal structure of rv0983 from mycobacterium tuberculosis-2 proteolytically active form 84 d1uepa_ not modelled 18.6 17 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 85 d2nn6i1 not modelled 18.5 33 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 86 d2fi9a1 not modelled 18.4 47 Fold:MTH938-like Superfamily:MTH938-like Family:MTH938-like 87 d1qvpa_ not modelled 17.8 39 Fold:SH3-like barrel Superfamily:C-terminal domain of transcriptional repressors Family:FeoA-like 88 c3k50A_ not modelled 17.7 19 PDB header:hydrolase Chain: A: PDB Molecule:putative s41 protease; PDBTitle: crystal structure of putative s41 protease (yp_211611.1) from2 bacteroides fragilis nctc 9343 at 2.00 a resolution 89 d2v4jc1 not modelled 17.5 43 Fold:DsrC, the gamma subunit of dissimilatory sulfite reductase Superfamily:DsrC, the gamma subunit of dissimilatory sulfite reductase Family:DsrC, the gamma subunit of dissimilatory sulfite reductase 90 c3qo6B_ not modelled 17.5 71 PDB header:photosynthesis Chain: B: PDB Molecule:protease do-like 1, chloroplastic; PDBTitle: crystal structure analysis of the plant protease deg1 91 c2es4D_ not modelled 17.3 21 PDB header:hydrolase Chain: D: PDB Molecule:lipase chaperone; PDBTitle: crystal structure of the burkholderia glumae lipase-2 specific foldase in complex with its cognate lipase 92 d2es4d1 not modelled 17.3 21 Fold:Non-globular all-alpha subunits of globular proteins Superfamily:Lipase chaperone-like Family:Lipase chaperone LifO-like 93 d1gmua1 not modelled 17.1 28 Fold:Urease metallochaperone UreE, N-terminal domain Superfamily:Urease metallochaperone UreE, N-terminal domain Family:Urease metallochaperone UreE, N-terminal domain 94 d2ba0a1 not modelled 17.0 17 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 95 c1lfwA_ not modelled 16.6 15 PDB header:hydrolase Chain: A: PDB Molecule:pepv; PDBTitle: crystal structure of pepv 96 d2plta_ not modelled 16.6 19 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Plastocyanin/azurin-like 97 c2edvA_ not modelled 16.4 16 PDB header:protein binding Chain: A: PDB Molecule:ferm and pdz domain-containing protein 1; PDBTitle: solution structure of the pdz domain from human ferm and2 pdz domain containing 1 98 c2q3gA_ not modelled 16.3 19 PDB header:structural genomics Chain: A: PDB Molecule:pdz and lim domain protein 7; PDBTitle: structure of the pdz domain of human pdlim7 bound to a c-2 terminal extension from human beta-tropomyosin 99 c2eqsA_ not modelled 16.3 14 PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent rna helicase dhx8; PDBTitle: solution structure of the s1 rna binding domain of human2 atp-dependent rna helicase dhx8

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0